- Yale Rheumatology (North Haven)6 Devine StreetFl 2 Ste 2BNorth Haven, CT 06473
- Yale Medicine Rheumatology (Orchard)Orchard Medical Center at St. Raphael’s Campus330 Orchard Street, Fl 3 Ste 300New Haven, CT 06511
Vaidehi R. Chowdhary, MBBS, MD
Biography
Vaidehi Chowdhary, MD, is a rheumatologist who treats people with autoimmune diseases, including gout, vasculitis, and different types of arthritis. She has a special interest in lupus, a complex disease in which the body attacks its own tissues and organs, causing pain, fatigue, and other symptoms.
Diseases like lupus can be difficult and painful, and patients express worry about how their condition will affect their lifestyles, Dr. Chowdhary says. But researchers are introducing a growing number of treatments for lupus and other rheumatologic diseases, including new medicines that target specific pathways in the immune system that cause inflammation and pain. While many medications are slow-acting, she says it’s rewarding to work with patients through the years and see them feel better over time. “You can give more patients hope, and I think that's a very powerful thing.”
Dr. Chowdhary, who worked at the Mayo Clinic before coming to Yale, says she became a doctor because she was inspired by the combination of science and art in medicine. “The good part is that you're never far away from people. I've learned so much from my patients—lessons of courage, lessons in resilience. It’s good to know that I can be an important part of their journey to healing,” she says. “I think rheumatologists are unique in that regard, in that they'll listen to patients, knowing that this is part of the disease. So, patients feel heard, and I think that's the first step.”
In addition to caring for patients, Dr. Chowdhary is an associate professor of rheumatology at Yale School of Medicine who participates in research into better treatment for people with rheumatologic disease. She advises anyone who has a family history or is concerned about symptoms to consult a rheumatologist. “The earlier we treat these diseases, the lesser the chance of these diseases leading to life-threatening manifestations,” she says.
Titles
- Associate Professor of Medicine (Rheumatology, Allergy & Immunology)
- Clinical Chief, Rheumatology, Allergy, & Immunology
Education & Training
- FellowMayo School of Graduate Medical Education (2008)
- ResidentMayo School of Graduate Medical Education (2005)
- Post-Doctoral FellowshipMayo Graduate School of Medicine (2003)
- MDMayo Graduate School of Medicine, Department of Immunology /Post Doctoral Fellowship (2000)
- DMSanjay Gandhi Post-Graduate Institute of Medical Sciences (1998)
- MDSassoon Hospitals, Byramjee Jeejeebhoy Medical College (1994)
- MBBSByramjee Jeejeebhoy Medical College (1991)
Additional Information
- Attending of the Year: Yale Rheumatology Fellows (2020)
- Senior Research Associateship: Council of Scientific Research (2019)
- Nelson Career Development Award: Mayo Foundation (2016)
- Department of Medicine Laureate Award: Mayo Clinic (2015)
- Nelson Career Development Award: Mayo Foundation (2013)
- John M Nasseff Sr Award honoring Dr Harvinder Luthra: Rheumatology/Internal Medicine Mayo Clinic (2013)
- Outstanding Abstract: American College of Rheumatology Research Conference (2012)
- Ronald F Kinney Executive Dean for Research Career Development Award: Mayo Clinic (2011)
- REF Career Development Bridge Funding Award: American College of Rheumatology (2010)
- Special Merit award: Indian Rheumatism Association conference (2008)
- Johnson S, Bernstein E, Bolster M, Chung J, Danoff S, George M, Khanna D, Guyatt G, Mirza R, Aggarwal R, Allen A, Assassi S, Buckley L, Chami H, Corwin D, Dellaripa P, Domsic R, Doyle T, Falardeau C, Frech T, Gibbons F, Hinchcliff M, Johnson C, Kanne J, Kim J, Lim S, Matson S, McMahan Z, Merck S, Nesbitt K, Scholand M, Shapiro L, Sharkey C, Summer R, Varga J, Warrier A, Agarwal S, Antin‐Ozerkis D, Bemiss B, Chowdhary V, D'Amico J, Hallowell R, Hinze A, Injean P, Jiwrajka N, Joerns E, Lee J, Makol A, McDermott G, Natalini J, Oldham J, Saygin D, Lakin K, Singh N, Solomon J, Sparks J, Turgunbaev M, Vaseer S, Turner A, Uhl S, Ivlev I. 2023 American College of Rheumatology (ACR)/American College of Chest Physicians (CHEST) Guideline for the Treatment of Interstitial Lung Disease in People with Systemic Autoimmune Rheumatic Diseases. Arthritis Care & Research 2024, 76: 1051-1069. PMID: 38973731, DOI: 10.1002/acr.25348.
- Johnson S, Bernstein E, Bolster M, Chung J, Danoff S, George M, Khanna D, Guyatt G, Mirza R, Aggarwal R, Allen A, Assassi S, Buckley L, Chami H, Corwin D, Dellaripa P, Domsic R, Doyle T, Falardeau C, Frech T, Gibbons F, Hinchcliff M, Johnson C, Kanne J, Kim J, Lim S, Matson S, McMahan Z, Merck S, Nesbitt K, Scholand M, Shapiro L, Sharkey C, Summer R, Varga J, Warrier A, Agarwal S, Antin‐Ozerkis D, Bemiss B, Chowdhary V, D'Amico J, Hallowell R, Hinze A, Injean P, Jiwrajka N, Joerns E, Lee J, Makol A, McDermott G, Natalini J, Oldham J, Saygin D, Lakin K, Singh N, Solomon J, Sparks J, Turgunbaev M, Vaseer S, Turner A, Uhl S, Ivlev I. 2023 American College of Rheumatology (ACR)/American College of Chest Physicians (CHEST) Guideline for the Treatment of Interstitial Lung Disease in People with Systemic Autoimmune Rheumatic Diseases. Arthritis & Rheumatology 2024, 76: 1182-1200. PMID: 38978310, DOI: 10.1002/art.42861.
- Johnson S, Bernstein E, Bolster M, Chung J, Danoff S, George M, Khanna D, Guyatt G, Mirza R, Aggarwal R, Allen A, Assassi S, Buckley L, Chami H, Corwin D, Dellaripa P, Domsic R, Doyle T, Falardeau C, Frech T, Gibbons F, Hinchcliff M, Johnson C, Kanne J, Kim J, Lim S, Matson S, McMahan Z, Merck S, Nesbitt K, Scholand M, Shapiro L, Sharkey C, Summer R, Varga J, Warrier A, Agarwal S, Antin‐Ozerkis D, Bemiss B, Chowdhary V, D'Amico J, Hallowell R, Hinze A, Injean P, Jiwrajka N, Joerns E, Lee J, Makol A, McDermott G, Natalini J, Oldham J, Saygin D, Lakin K, Singh N, Solomon J, Sparks J, Turgunbaev M, Vaseer S, Turner A, Uhl S, Ivlev I. 2023 American College of Rheumatology (ACR)/American College of Chest Physicians (CHEST) Guideline for the Screening and Monitoring of Interstitial Lung Disease in People with Systemic Autoimmune Rheumatic Diseases. Arthritis Care & Research 2024, 76: 1070-1082. PMID: 38973729, DOI: 10.1002/acr.25347.
- Johnson S, Bernstein E, Bolster M, Chung J, Danoff S, George M, Khanna D, Guyatt G, Mirza R, Aggarwal R, Allen A, Assassi S, Buckley L, Chami H, Corwin D, Dellaripa P, Domsic R, Doyle T, Falardeau C, Frech T, Gibbons F, Hinchcliff M, Johnson C, Kanne J, Kim J, Lim S, Matson S, McMahan Z, Merck S, Nesbitt K, Scholand M, Shapiro L, Sharkey C, Summer R, Varga J, Warrier A, Agarwal S, Antin‐Ozerkis D, Bemiss B, Chowdhary V, D'Amico J, Hallowell R, Hinze A, Injean P, Jiwrajka N, Joerns E, Lee J, Makol A, McDermott G, Natalini J, Oldham J, Saygin D, Lakin K, Singh N, Solomon J, Sparks J, Turgunbaev M, Vaseer S, Turner A, Uhl S, Ivlev I. 2023 American College of Rheumatology (ACR)/American College of Chest Physicians (CHEST) Guideline for the Screening and Monitoring of Interstitial Lung Disease in People with Systemic Autoimmune Rheumatic Diseases. Arthritis & Rheumatology 2024, 76: 1201-1213. PMID: 38973714, DOI: 10.1002/art.42860.
- Palacios C, Chowdhary V, Hao R, Danve A, Malinis M. Is yearly interferon gamma release assay latent tuberculosis infection screening warranted among patients with rheumatological diseases on disease-modifying drugs in non-endemic settings? PLOS ONE 2024, 19: e0306337. PMID: 38959249, PMCID: PMC11221665, DOI: 10.1371/journal.pone.0306337.
- Nln I, Shum J, Ghodke-Puranik Y, Tipon R, Triese D, Amin S, Makol A, Osborn T, Chowdhary V, Thanarajasingam U, Muskardin T, Oke V, Gunnarsson I, Zickert A, Zervou M, Boumpas D, Svenungsson E, Goulielmos G, Niewold T. Regional European genetic ancestry predicts type I interferon level and risk of severe viral infection. QJM 2024, 117: 581-588. PMID: 38530799, PMCID: PMC11389909, DOI: 10.1093/qjmed/hcae052.
- Baker H, Fine R, Suter F, Allore H, Hsiao B, Chowdhary V, Lavelle E, Chen P, Hintz R, Suter L, Danve A. Implementation of a Best Practice Advisory to Improve Infection Screening Prior to New Prescriptions of Biologics and Targeted Synthetic Drugs. Arthritis Care & Research 2023 PMID: 37382043, DOI: 10.1002/acr.25181.
- Iwamoto T, Dorschner J, Jensen M, Vsetecka D, Amin S, Makol A, Ernste F, Osborn T, Moder K, Chowdhary V, Niewold T. TD-08 High type I interferon activity is associated with active class III/IV lupus nephritis in european-american lupus patients independent of anti-dsDNA antibodies. 2018, a75.2-a76. DOI: 10.1136/lupus-2018-lsm.127.
- Bugdayli K, Chowdhary V, Crowson C, Zand L, Alexander M, Cornell L. FRI0371 Clinical characteristics and outcome of isolated lupus nephritis. Annals Of The Rheumatic Diseases 2018, 77: 720. DOI: 10.1136/annrheumdis-2018-eular.6053.
- Iwamoto T, Dorschner J, Jensen M, Vsetecka D, Amin S, Makol A, Ernste F, Osborn T, Moder K, Chowdhary V, Niewold T. PS1:1 High type i interferon activity is associated with active class 3/4 lupus nephritis in european-american lupus patients independent of anti-dsdna antibodies. 2018, a32.1-a32. DOI: 10.1136/lupus-2018-abstract.50.
- Ghodke-Puranik Y, Zhongbo J, Fan W, Jensen M, Dorschner J, Vsetecka D, Amin S, Makol A, Ernste F, Osborn T, Moder K, Chowdhary V, Niewold T. 10 Single cell expression quantitative trait LOCI (EQTL) analsis of established lupus-risk loci in patient monocytes. Lupus Science & Medicine 2017, 4: a6. DOI: 10.1136/lupus-2017-000215.10.
- Jin Z, Fan W, Jensen M, Dorschner J, Vsetecka D, Amin S, Makol A, Ernste F, Osborn T, Moder K, Chowdhary V, Niewold T. GG-06 Single cell gene expression studies in lupus patient monocytes reveal novel patterns reflecting disease activity, interferon, and medical treatment. Lupus Science & Medicine 2016, 3: a30. DOI: 10.1136/lupus-2016-000179.58.
- Ungprasert P, Sagar V, Crowson C, Amin S, Makol A, Ernste F, Osborn T, Moder K, Niewold T, Maradit-Kremers H, Ramsey-Goldman R, Chowdhary V. Incidence of systemic lupus erythematosus in a population-based cohort using revised 1997 American College of Rheumatology and the 2012 Systemic Lupus International Collaborating Clinics classification criteria. Lupus 2016, 26: 240-247. PMID: 27365370, PMCID: PMC5201452, DOI: 10.1177/0961203316657434.
- Jin Z, Jensen M, Dorschner J, Vsetecka D, Amin S, Makol A, Ernste F, Osborn T, Moder K, Chowdhary V, Niewold T, Fan W. ID: 135: SINGLE CELL GENE EXPRESSION STUDIES IN LUPUS MONOCYTES REVEAL A UNIQUE ANTII-INFLAMMATORY NON-CLASSICAL MONOCYTE POPULATION ASSOCIATED WITH CLINICAL QUIESCENCE. Journal Of Investigative Medicine 2016, 64: 977. DOI: 10.1136/jim-2016-000120.138.
- Ungprasert P, Chowdhary V, Davis M, Makol A. Autoimmune myelofibrosis with pancytopenia as a presenting manifestation of systemic lupus erythematosus responsive to mycophenolate mofetil. Lupus 2015, 25: 427-430. PMID: 26537421, DOI: 10.1177/0961203315615221.
- Jin Z, Fan W, Jensen M, Dorschner J, Vsetecka D, Amin S, Makol A, Ernste F, Osborn T, Moder K, Chowdhary V, Niewold T. ID: 209 Single cell interferon signatures in lupus patient monocytes reveal a differential impact of interferon signaling between monocyte subtypes. Cytokine 2015, 76: 102-103. DOI: 10.1016/j.cyto.2015.08.213.
- Jin Z, Fan W, Jensen M, Dorschner J, Vsetecka D, Amin S, Makol A, Ernste F, Osborn T, Moder K, Chowdhary V, Niewold T. THU0022 Single Cell Interferon Signatures in Lupus Patient Monocytes Reveal a Differential Impact of Interferon Signaling Between Monocyte Subtypes. Annals Of The Rheumatic Diseases 2015, 74: 200. DOI: 10.1136/annrheumdis-2015-eular.5326.
- Sagar V, Crowson C, Amin S, Makol A, Ernste F, Osborn T, Moder K, Niewold T, Maradit-Kremers H, Chowdhary V. THU0372 Incidence of Systemic Lupus Erythematosus (SLE) in a Population Based Cohort Using 1982, Revised 1997 ACR and 2012 SLICC Criteria. Annals Of The Rheumatic Diseases 2015, 74: 330. DOI: 10.1136/annrheumdis-2015-eular.4180.
- Singh A, Crowson C, Davis M, Maradit-Kremers H, Matteson E, Chowdhary V. THU0329 Risk of Cancer is not Increased in Patients with Cutaneous Lupus Erythematosus: A Population-Based Study. Annals Of The Rheumatic Diseases 2015, 74: 314. DOI: 10.1136/annrheumdis-2015-eular.4320.
- Singh A, Crowson C, Davis M, Maradit-Kremers H, Matteson E, Chowdhary V. AB0539 Risk of Cardiovascular Events in Patients with Cutaneous Lupus Erythematosus: A Population-Based Study. Annals Of The Rheumatic Diseases 2015, 74: 1080. DOI: 10.1136/annrheumdis-2015-eular.4318.
- Jarukitsopa S, Hoganson DD, Crowson CS, Sokumbi O, Davis MD, Michet CJ, Matteson EL, Maradit Kremers H, Chowdhary VR. Epidemiology of Systemic Lupus Erythematosus and Cutaneous Lupus Erythematosus in a Predominantly White Population in the United States. Arthritis Care & Research 2015, 67: 817-828. PMID: 25369985, PMCID: PMC4418944, DOI: 10.1002/acr.22502.
- Chung J, Greenwood-Quaintance K, Karau MJ, Tilahun A, Khaleghi SR, Chowdhary VR, David CS, Patel R, Rajagopalan G. Superantigens produced by catheter-associated Staphylococcus aureus elicit systemic inflammatory disease in the absence of bacteremia. Journal Of Leukocyte Biology 2015, 98: 271-281. PMID: 25979434, PMCID: PMC4501677, DOI: 10.1189/jlb.4a1214-577rr.
- Niewold T, Jensen M, Dorschner J, Vsetecka D, Amin S, Makol A, Ernste F, Osborn T, Moder K, Chowdhary V, Jin Z. Single cell gene expression in lupus patient monocytes reveals a differential impact of interferon signaling between monocyte subtypes (TECH2P.920). The Journal Of Immunology 2015, 194: 206.30-206.30. DOI: 10.4049/jimmunol.194.supp.206.30.
- Synovial Infiltration in Human T Lymphotropic Virus Type I–Associated Adult T Cell Leukemia/LymphomaKoster MJ, McPhail ED, Chowdhary VR. Synovial Infiltration in Human T Lymphotropic Virus Type I–Associated Adult T Cell Leukemia/Lymphoma. Arthritis & Rheumatology 2015, 67: 945-945. PMID: 25604902, DOI: 10.1002/art.39038.
- Singh AG, Chowdhary VR. Pregnancy‐related issues in women with systemic lupus erythematosus. International Journal Of Rheumatic Diseases 2014, 18: 172-181. PMID: 25545844, DOI: 10.1111/1756-185x.12524.
- Flanagan EP, Chowdhary VR, McCarthy JT, Smyrk TC, Chari ST, Kumar N. IgG4‐related (neurologic) disease: diagnostic challenges, clinical clues and expanding spectrum. International Journal Of Rheumatic Diseases 2014, 18: 807-809. PMID: 25307728, DOI: 10.1111/1756-185x.12465.
- Tilahun AY, Chowdhary VR, David CS, Rajagopalan G. Systemic Inflammatory Response Elicited by Superantigen Destabilizes T Regulatory Cells, Rendering Them Ineffective during Toxic Shock Syndrome. The Journal Of Immunology 2014, 193: 2919-2930. PMID: 25092888, PMCID: PMC4157092, DOI: 10.4049/jimmunol.1400980.
- Chowdhary V, Crowson C, Maradit-Kremers H, Davis M. SAT0100 Incidence of Systemic Lupus Erythematosus and Cutaneous Lupus Erythematosuis in A Population Based Cohort from 1993-2005. Annals Of The Rheumatic Diseases 2014, 73: 626. DOI: 10.1136/annrheumdis-2014-eular.1183.
- Rajagopalan G, Tilahun A, Chowdhary V. Chronic activation with a staphylococcal superantigen drives the expansion of CD4, CD8 double negative T cells and promotes multiorgan inflammation mimicking systemic lupus erythematosus in HLA class II transgenic mice. (HUM7P.306). The Journal Of Immunology 2014, 192: 184.15-184.15. DOI: 10.4049/jimmunol.192.supp.184.15.
- Chowdhary VR, Crowson CS, Bhagra AS, Warrington KJ, Vrtiska TJ. CT angiographic imaging characteristics of thoracic idiopathic aortitis. Journal Of Cardiovascular Computed Tomography 2013, 7: 297-302. PMID: 24268116, DOI: 10.1016/j.jcct.2013.08.009.
- LUDVIGSSON JF, RUBIO-TAPIA A, CHOWDHARY V, MURRAY JA, SIMARD JF. Dr. Ludvigsson, et al reply. The Journal Of Rheumatology 2013, 40: 1619-1619. PMID: 24137770, DOI: 10.3899/jrheum.130623.
- Chowdhary V, Crowson C, Warrington K, Vrtiska T. AB0777 Computed tomodensitometric (CT) angiographic imaging characteristics of idiopathic aortitis: A case control study. Annals Of The Rheumatic Diseases 2013, 71: 683. DOI: 10.1136/annrheumdis-2012-eular.777.
- Krause ML, Boland JM, Maleszewski JJ, Gilbertson JR, Chowdhary VR. An unusual cause of diffuse pulmonary infiltrates. Arthritis Care & Research 2013, 65: 487-490. PMID: 23002027, DOI: 10.1002/acr.21860.
- Chauhan K, Hart P, Chowdhary V. Immunoglobulin G4 (IgG4) Related Disease. 2012, 73-88. DOI: 10.1007/978-1-4614-5088-7_5.
- Chowdhary VR, Tilahun AY, Clark CR, Grande JP, Rajagopalan G. Chronic Exposure to Staphylococcal Superantigen Elicits a Systemic Inflammatory Disease Mimicking Lupus. The Journal Of Immunology 2012, 189: 2054-2062. PMID: 22798666, PMCID: PMC3462343, DOI: 10.4049/jimmunol.1201097.
- Ludvigsson JF, Rubio-Tapia A, Chowdhary V, Murray JA, Simard JF. Increased Risk of Systemic Lupus Erythematosus in 29,000 Patients with Biopsy-verified Celiac Disease. The Journal Of Rheumatology 2012, 39: 1964-1970. PMID: 22859356, PMCID: PMC3463642, DOI: 10.3899/jrheum.120493.
- Makol A, Watt KD, Chowdhary VR. Autoimmune Hepatitis: A Review of Current Diagnosis and Treatment. Hepatitis Research And Treatment 2011, 2011: 390916. PMID: 21760995, PMCID: PMC3132488, DOI: 10.1155/2011/390916.
- Liang KP, Chowdhary VR, Michet CJ, Miller DV, Sundt TM, Connolly HM, Crowson CS, Matteson EL, Warrington KJ. Noninfectious Ascending Aortitis: A Case Series of 64 Patients. The Journal Of Rheumatology 2009, 36: 2290-2297. PMID: 19648309, DOI: 10.3899/jrheum.090081.
- Chowdhary VR, Crowson CS, Liang KP, Michet CJ, Miller DV, Warrington KJ, Matteson EL. Cardiovascular risk factors and acute-phase response in idiopathic ascending aortitis: a case control study. Arthritis Research & Therapy 2009, 11: r29. PMID: 19250534, PMCID: PMC2688264, DOI: 10.1186/ar2633.
- Chowdhary VR, Crowson CS, Poterucha JJ, Moder KG. Liver Involvement in Systemic Lupus Erythematosus: Case Review of 40 Patients. The Journal Of Rheumatology 2008, 35: 2159-2164. PMID: 18793002, DOI: 10.3899/jrheum.080336.
- Chowdhary V, Kallmes DF, Fulgham J, Meyer F, Matteson EL. Recurrent spells and bilateral internal carotid artery stenosis in a diabetic male: A test of patien‐ce(‐ts). Arthritis & Rheumatism 2007, 57: 1098-1101. PMID: 17665478, DOI: 10.1002/art.22905.
- Chowdhary V, Grande J, Luthra H, David C. Characterization of haemorrhagic pulmonary capillaritis: another manifestation of Pristane-induced lupus. Rheumatology 2007, 46: 1405-1410. PMID: 17576695, DOI: 10.1093/rheumatology/kem117.
- Xue A, Chapoval SP, Finn ES, Chowdhary VR, Marietta EV, Gaffey TA, Pursifull AC, David CS. HLA-DQ8 is a predisposing molecule for detergent enzyme subtilisin BPN′-induced hypersensitivity. Clinical Immunology 2005, 117: 302-315. PMID: 16185928, DOI: 10.1016/j.clim.2005.08.003.
- Finn E, Chapoval S, Xue A, Chowdhary V, Marietta E, Gaffey T, Pursifull A, David C. HLA Class II transgenic mice as models to study the allergenicity of bacterial protease Y217L BPN'. Journal Of Allergy And Clinical Immunology 2004, 113: s141. DOI: 10.1016/j.jaci.2003.12.506.
- Chowdhary V, Wakhlu A, Agarwal A, Misra R. Outcome in juvenile dermatomyositis. Indian Pediatrics 2002, 39: 931-5. PMID: 12428038.
- Paisansinsup T, Deshmukh US, Chowdhary VR, Luthra HS, Fu SM, David CS. HLA Class II Influences the Immune Response and Antibody Diversification to Ro60/Sjögren’s Syndrome-A: Heightened Antibody Responses and Epitope Spreading in Mice Expressing HLA-DR molecules. The Journal Of Immunology 2002, 168: 5876-5884. PMID: 12023392, DOI: 10.4049/jimmunol.168.11.5876.
- Chowdhary V, Aggarwal A, Misra R. Multifocal Tubercular Dactylitis in an Adult. JCR Journal Of Clinical Rheumatology 2002, 8: 35-37. PMID: 17039198, DOI: 10.1097/00124743-200202000-00008.
- Chowdhary V, Nityanand S, Prasad K, Pandey R, Dabadghao S. Sweet's syndrome and Pneumocystis carinii pneumonia: two sequelae of low‐dose cytosine arabinoside therapy in a patient with acute myeloid leukemia. European Journal Of Haematology 2000, 65: 72-73. PMID: 10914942, DOI: 10.1034/j.1600-0609.2000.9c177.x.
- Yale Rheumatology (North Haven)6 Devine StreetFl 2 Ste 2BNorth Haven, CT 06473
- Yale Medicine Rheumatology (Orchard)Orchard Medical Center at St. Raphael’s Campus330 Orchard Street, Fl 3 Ste 300New Haven, CT 06511
Biography
Vaidehi Chowdhary, MD, is a rheumatologist who treats people with autoimmune diseases, including gout, vasculitis, and different types of arthritis. She has a special interest in lupus, a complex disease in which the body attacks its own tissues and organs, causing pain, fatigue, and other symptoms.
Diseases like lupus can be difficult and painful, and patients express worry about how their condition will affect their lifestyles, Dr. Chowdhary says. But researchers are introducing a growing number of treatments for lupus and other rheumatologic diseases, including new medicines that target specific pathways in the immune system that cause inflammation and pain. While many medications are slow-acting, she says it’s rewarding to work with patients through the years and see them feel better over time. “You can give more patients hope, and I think that's a very powerful thing.”
Dr. Chowdhary, who worked at the Mayo Clinic before coming to Yale, says she became a doctor because she was inspired by the combination of science and art in medicine. “The good part is that you're never far away from people. I've learned so much from my patients—lessons of courage, lessons in resilience. It’s good to know that I can be an important part of their journey to healing,” she says. “I think rheumatologists are unique in that regard, in that they'll listen to patients, knowing that this is part of the disease. So, patients feel heard, and I think that's the first step.”
In addition to caring for patients, Dr. Chowdhary is an associate professor of rheumatology at Yale School of Medicine who participates in research into better treatment for people with rheumatologic disease. She advises anyone who has a family history or is concerned about symptoms to consult a rheumatologist. “The earlier we treat these diseases, the lesser the chance of these diseases leading to life-threatening manifestations,” she says.
Titles
- Associate Professor of Medicine (Rheumatology, Allergy & Immunology)
- Clinical Chief, Rheumatology, Allergy, & Immunology
Education & Training
- FellowMayo School of Graduate Medical Education (2008)
- ResidentMayo School of Graduate Medical Education (2005)
- Post-Doctoral FellowshipMayo Graduate School of Medicine (2003)
- MDMayo Graduate School of Medicine, Department of Immunology /Post Doctoral Fellowship (2000)
- DMSanjay Gandhi Post-Graduate Institute of Medical Sciences (1998)
- MDSassoon Hospitals, Byramjee Jeejeebhoy Medical College (1994)
- MBBSByramjee Jeejeebhoy Medical College (1991)
Additional Information
- Attending of the Year: Yale Rheumatology Fellows (2020)
- Senior Research Associateship: Council of Scientific Research (2019)
- Nelson Career Development Award: Mayo Foundation (2016)
- Department of Medicine Laureate Award: Mayo Clinic (2015)
- Nelson Career Development Award: Mayo Foundation (2013)
- John M Nasseff Sr Award honoring Dr Harvinder Luthra: Rheumatology/Internal Medicine Mayo Clinic (2013)
- Outstanding Abstract: American College of Rheumatology Research Conference (2012)
- Ronald F Kinney Executive Dean for Research Career Development Award: Mayo Clinic (2011)
- REF Career Development Bridge Funding Award: American College of Rheumatology (2010)
- Special Merit award: Indian Rheumatism Association conference (2008)
- Johnson S, Bernstein E, Bolster M, Chung J, Danoff S, George M, Khanna D, Guyatt G, Mirza R, Aggarwal R, Allen A, Assassi S, Buckley L, Chami H, Corwin D, Dellaripa P, Domsic R, Doyle T, Falardeau C, Frech T, Gibbons F, Hinchcliff M, Johnson C, Kanne J, Kim J, Lim S, Matson S, McMahan Z, Merck S, Nesbitt K, Scholand M, Shapiro L, Sharkey C, Summer R, Varga J, Warrier A, Agarwal S, Antin‐Ozerkis D, Bemiss B, Chowdhary V, D'Amico J, Hallowell R, Hinze A, Injean P, Jiwrajka N, Joerns E, Lee J, Makol A, McDermott G, Natalini J, Oldham J, Saygin D, Lakin K, Singh N, Solomon J, Sparks J, Turgunbaev M, Vaseer S, Turner A, Uhl S, Ivlev I. 2023 American College of Rheumatology (ACR)/American College of Chest Physicians (CHEST) Guideline for the Treatment of Interstitial Lung Disease in People with Systemic Autoimmune Rheumatic Diseases. Arthritis Care & Research 2024, 76: 1051-1069. PMID: 38973731, DOI: 10.1002/acr.25348.
- Johnson S, Bernstein E, Bolster M, Chung J, Danoff S, George M, Khanna D, Guyatt G, Mirza R, Aggarwal R, Allen A, Assassi S, Buckley L, Chami H, Corwin D, Dellaripa P, Domsic R, Doyle T, Falardeau C, Frech T, Gibbons F, Hinchcliff M, Johnson C, Kanne J, Kim J, Lim S, Matson S, McMahan Z, Merck S, Nesbitt K, Scholand M, Shapiro L, Sharkey C, Summer R, Varga J, Warrier A, Agarwal S, Antin‐Ozerkis D, Bemiss B, Chowdhary V, D'Amico J, Hallowell R, Hinze A, Injean P, Jiwrajka N, Joerns E, Lee J, Makol A, McDermott G, Natalini J, Oldham J, Saygin D, Lakin K, Singh N, Solomon J, Sparks J, Turgunbaev M, Vaseer S, Turner A, Uhl S, Ivlev I. 2023 American College of Rheumatology (ACR)/American College of Chest Physicians (CHEST) Guideline for the Treatment of Interstitial Lung Disease in People with Systemic Autoimmune Rheumatic Diseases. Arthritis & Rheumatology 2024, 76: 1182-1200. PMID: 38978310, DOI: 10.1002/art.42861.
- Johnson S, Bernstein E, Bolster M, Chung J, Danoff S, George M, Khanna D, Guyatt G, Mirza R, Aggarwal R, Allen A, Assassi S, Buckley L, Chami H, Corwin D, Dellaripa P, Domsic R, Doyle T, Falardeau C, Frech T, Gibbons F, Hinchcliff M, Johnson C, Kanne J, Kim J, Lim S, Matson S, McMahan Z, Merck S, Nesbitt K, Scholand M, Shapiro L, Sharkey C, Summer R, Varga J, Warrier A, Agarwal S, Antin‐Ozerkis D, Bemiss B, Chowdhary V, D'Amico J, Hallowell R, Hinze A, Injean P, Jiwrajka N, Joerns E, Lee J, Makol A, McDermott G, Natalini J, Oldham J, Saygin D, Lakin K, Singh N, Solomon J, Sparks J, Turgunbaev M, Vaseer S, Turner A, Uhl S, Ivlev I. 2023 American College of Rheumatology (ACR)/American College of Chest Physicians (CHEST) Guideline for the Screening and Monitoring of Interstitial Lung Disease in People with Systemic Autoimmune Rheumatic Diseases. Arthritis Care & Research 2024, 76: 1070-1082. PMID: 38973729, DOI: 10.1002/acr.25347.
- Johnson S, Bernstein E, Bolster M, Chung J, Danoff S, George M, Khanna D, Guyatt G, Mirza R, Aggarwal R, Allen A, Assassi S, Buckley L, Chami H, Corwin D, Dellaripa P, Domsic R, Doyle T, Falardeau C, Frech T, Gibbons F, Hinchcliff M, Johnson C, Kanne J, Kim J, Lim S, Matson S, McMahan Z, Merck S, Nesbitt K, Scholand M, Shapiro L, Sharkey C, Summer R, Varga J, Warrier A, Agarwal S, Antin‐Ozerkis D, Bemiss B, Chowdhary V, D'Amico J, Hallowell R, Hinze A, Injean P, Jiwrajka N, Joerns E, Lee J, Makol A, McDermott G, Natalini J, Oldham J, Saygin D, Lakin K, Singh N, Solomon J, Sparks J, Turgunbaev M, Vaseer S, Turner A, Uhl S, Ivlev I. 2023 American College of Rheumatology (ACR)/American College of Chest Physicians (CHEST) Guideline for the Screening and Monitoring of Interstitial Lung Disease in People with Systemic Autoimmune Rheumatic Diseases. Arthritis & Rheumatology 2024, 76: 1201-1213. PMID: 38973714, DOI: 10.1002/art.42860.
- Palacios C, Chowdhary V, Hao R, Danve A, Malinis M. Is yearly interferon gamma release assay latent tuberculosis infection screening warranted among patients with rheumatological diseases on disease-modifying drugs in non-endemic settings? PLOS ONE 2024, 19: e0306337. PMID: 38959249, PMCID: PMC11221665, DOI: 10.1371/journal.pone.0306337.
- Nln I, Shum J, Ghodke-Puranik Y, Tipon R, Triese D, Amin S, Makol A, Osborn T, Chowdhary V, Thanarajasingam U, Muskardin T, Oke V, Gunnarsson I, Zickert A, Zervou M, Boumpas D, Svenungsson E, Goulielmos G, Niewold T. Regional European genetic ancestry predicts type I interferon level and risk of severe viral infection. QJM 2024, 117: 581-588. PMID: 38530799, PMCID: PMC11389909, DOI: 10.1093/qjmed/hcae052.
- Baker H, Fine R, Suter F, Allore H, Hsiao B, Chowdhary V, Lavelle E, Chen P, Hintz R, Suter L, Danve A. Implementation of a Best Practice Advisory to Improve Infection Screening Prior to New Prescriptions of Biologics and Targeted Synthetic Drugs. Arthritis Care & Research 2023 PMID: 37382043, DOI: 10.1002/acr.25181.
- Iwamoto T, Dorschner J, Jensen M, Vsetecka D, Amin S, Makol A, Ernste F, Osborn T, Moder K, Chowdhary V, Niewold T. TD-08 High type I interferon activity is associated with active class III/IV lupus nephritis in european-american lupus patients independent of anti-dsDNA antibodies. 2018, a75.2-a76. DOI: 10.1136/lupus-2018-lsm.127.
- Bugdayli K, Chowdhary V, Crowson C, Zand L, Alexander M, Cornell L. FRI0371 Clinical characteristics and outcome of isolated lupus nephritis. Annals Of The Rheumatic Diseases 2018, 77: 720. DOI: 10.1136/annrheumdis-2018-eular.6053.
- Iwamoto T, Dorschner J, Jensen M, Vsetecka D, Amin S, Makol A, Ernste F, Osborn T, Moder K, Chowdhary V, Niewold T. PS1:1 High type i interferon activity is associated with active class 3/4 lupus nephritis in european-american lupus patients independent of anti-dsdna antibodies. 2018, a32.1-a32. DOI: 10.1136/lupus-2018-abstract.50.
- Ghodke-Puranik Y, Zhongbo J, Fan W, Jensen M, Dorschner J, Vsetecka D, Amin S, Makol A, Ernste F, Osborn T, Moder K, Chowdhary V, Niewold T. 10 Single cell expression quantitative trait LOCI (EQTL) analsis of established lupus-risk loci in patient monocytes. Lupus Science & Medicine 2017, 4: a6. DOI: 10.1136/lupus-2017-000215.10.
- Jin Z, Fan W, Jensen M, Dorschner J, Vsetecka D, Amin S, Makol A, Ernste F, Osborn T, Moder K, Chowdhary V, Niewold T. GG-06 Single cell gene expression studies in lupus patient monocytes reveal novel patterns reflecting disease activity, interferon, and medical treatment. Lupus Science & Medicine 2016, 3: a30. DOI: 10.1136/lupus-2016-000179.58.
- Ungprasert P, Sagar V, Crowson C, Amin S, Makol A, Ernste F, Osborn T, Moder K, Niewold T, Maradit-Kremers H, Ramsey-Goldman R, Chowdhary V. Incidence of systemic lupus erythematosus in a population-based cohort using revised 1997 American College of Rheumatology and the 2012 Systemic Lupus International Collaborating Clinics classification criteria. Lupus 2016, 26: 240-247. PMID: 27365370, PMCID: PMC5201452, DOI: 10.1177/0961203316657434.
- Jin Z, Jensen M, Dorschner J, Vsetecka D, Amin S, Makol A, Ernste F, Osborn T, Moder K, Chowdhary V, Niewold T, Fan W. ID: 135: SINGLE CELL GENE EXPRESSION STUDIES IN LUPUS MONOCYTES REVEAL A UNIQUE ANTII-INFLAMMATORY NON-CLASSICAL MONOCYTE POPULATION ASSOCIATED WITH CLINICAL QUIESCENCE. Journal Of Investigative Medicine 2016, 64: 977. DOI: 10.1136/jim-2016-000120.138.
- Ungprasert P, Chowdhary V, Davis M, Makol A. Autoimmune myelofibrosis with pancytopenia as a presenting manifestation of systemic lupus erythematosus responsive to mycophenolate mofetil. Lupus 2015, 25: 427-430. PMID: 26537421, DOI: 10.1177/0961203315615221.
- Jin Z, Fan W, Jensen M, Dorschner J, Vsetecka D, Amin S, Makol A, Ernste F, Osborn T, Moder K, Chowdhary V, Niewold T. ID: 209 Single cell interferon signatures in lupus patient monocytes reveal a differential impact of interferon signaling between monocyte subtypes. Cytokine 2015, 76: 102-103. DOI: 10.1016/j.cyto.2015.08.213.
- Jin Z, Fan W, Jensen M, Dorschner J, Vsetecka D, Amin S, Makol A, Ernste F, Osborn T, Moder K, Chowdhary V, Niewold T. THU0022 Single Cell Interferon Signatures in Lupus Patient Monocytes Reveal a Differential Impact of Interferon Signaling Between Monocyte Subtypes. Annals Of The Rheumatic Diseases 2015, 74: 200. DOI: 10.1136/annrheumdis-2015-eular.5326.
- Sagar V, Crowson C, Amin S, Makol A, Ernste F, Osborn T, Moder K, Niewold T, Maradit-Kremers H, Chowdhary V. THU0372 Incidence of Systemic Lupus Erythematosus (SLE) in a Population Based Cohort Using 1982, Revised 1997 ACR and 2012 SLICC Criteria. Annals Of The Rheumatic Diseases 2015, 74: 330. DOI: 10.1136/annrheumdis-2015-eular.4180.
- Singh A, Crowson C, Davis M, Maradit-Kremers H, Matteson E, Chowdhary V. THU0329 Risk of Cancer is not Increased in Patients with Cutaneous Lupus Erythematosus: A Population-Based Study. Annals Of The Rheumatic Diseases 2015, 74: 314. DOI: 10.1136/annrheumdis-2015-eular.4320.
- Singh A, Crowson C, Davis M, Maradit-Kremers H, Matteson E, Chowdhary V. AB0539 Risk of Cardiovascular Events in Patients with Cutaneous Lupus Erythematosus: A Population-Based Study. Annals Of The Rheumatic Diseases 2015, 74: 1080. DOI: 10.1136/annrheumdis-2015-eular.4318.
- Jarukitsopa S, Hoganson DD, Crowson CS, Sokumbi O, Davis MD, Michet CJ, Matteson EL, Maradit Kremers H, Chowdhary VR. Epidemiology of Systemic Lupus Erythematosus and Cutaneous Lupus Erythematosus in a Predominantly White Population in the United States. Arthritis Care & Research 2015, 67: 817-828. PMID: 25369985, PMCID: PMC4418944, DOI: 10.1002/acr.22502.
- Chung J, Greenwood-Quaintance K, Karau MJ, Tilahun A, Khaleghi SR, Chowdhary VR, David CS, Patel R, Rajagopalan G. Superantigens produced by catheter-associated Staphylococcus aureus elicit systemic inflammatory disease in the absence of bacteremia. Journal Of Leukocyte Biology 2015, 98: 271-281. PMID: 25979434, PMCID: PMC4501677, DOI: 10.1189/jlb.4a1214-577rr.
- Niewold T, Jensen M, Dorschner J, Vsetecka D, Amin S, Makol A, Ernste F, Osborn T, Moder K, Chowdhary V, Jin Z. Single cell gene expression in lupus patient monocytes reveals a differential impact of interferon signaling between monocyte subtypes (TECH2P.920). The Journal Of Immunology 2015, 194: 206.30-206.30. DOI: 10.4049/jimmunol.194.supp.206.30.
- Synovial Infiltration in Human T Lymphotropic Virus Type I–Associated Adult T Cell Leukemia/LymphomaKoster MJ, McPhail ED, Chowdhary VR. Synovial Infiltration in Human T Lymphotropic Virus Type I–Associated Adult T Cell Leukemia/Lymphoma. Arthritis & Rheumatology 2015, 67: 945-945. PMID: 25604902, DOI: 10.1002/art.39038.
- Singh AG, Chowdhary VR. Pregnancy‐related issues in women with systemic lupus erythematosus. International Journal Of Rheumatic Diseases 2014, 18: 172-181. PMID: 25545844, DOI: 10.1111/1756-185x.12524.
- Flanagan EP, Chowdhary VR, McCarthy JT, Smyrk TC, Chari ST, Kumar N. IgG4‐related (neurologic) disease: diagnostic challenges, clinical clues and expanding spectrum. International Journal Of Rheumatic Diseases 2014, 18: 807-809. PMID: 25307728, DOI: 10.1111/1756-185x.12465.
- Tilahun AY, Chowdhary VR, David CS, Rajagopalan G. Systemic Inflammatory Response Elicited by Superantigen Destabilizes T Regulatory Cells, Rendering Them Ineffective during Toxic Shock Syndrome. The Journal Of Immunology 2014, 193: 2919-2930. PMID: 25092888, PMCID: PMC4157092, DOI: 10.4049/jimmunol.1400980.
- Chowdhary V, Crowson C, Maradit-Kremers H, Davis M. SAT0100 Incidence of Systemic Lupus Erythematosus and Cutaneous Lupus Erythematosuis in A Population Based Cohort from 1993-2005. Annals Of The Rheumatic Diseases 2014, 73: 626. DOI: 10.1136/annrheumdis-2014-eular.1183.
- Rajagopalan G, Tilahun A, Chowdhary V. Chronic activation with a staphylococcal superantigen drives the expansion of CD4, CD8 double negative T cells and promotes multiorgan inflammation mimicking systemic lupus erythematosus in HLA class II transgenic mice. (HUM7P.306). The Journal Of Immunology 2014, 192: 184.15-184.15. DOI: 10.4049/jimmunol.192.supp.184.15.
- Chowdhary VR, Crowson CS, Bhagra AS, Warrington KJ, Vrtiska TJ. CT angiographic imaging characteristics of thoracic idiopathic aortitis. Journal Of Cardiovascular Computed Tomography 2013, 7: 297-302. PMID: 24268116, DOI: 10.1016/j.jcct.2013.08.009.
- LUDVIGSSON JF, RUBIO-TAPIA A, CHOWDHARY V, MURRAY JA, SIMARD JF. Dr. Ludvigsson, et al reply. The Journal Of Rheumatology 2013, 40: 1619-1619. PMID: 24137770, DOI: 10.3899/jrheum.130623.
- Chowdhary V, Crowson C, Warrington K, Vrtiska T. AB0777 Computed tomodensitometric (CT) angiographic imaging characteristics of idiopathic aortitis: A case control study. Annals Of The Rheumatic Diseases 2013, 71: 683. DOI: 10.1136/annrheumdis-2012-eular.777.
- Krause ML, Boland JM, Maleszewski JJ, Gilbertson JR, Chowdhary VR. An unusual cause of diffuse pulmonary infiltrates. Arthritis Care & Research 2013, 65: 487-490. PMID: 23002027, DOI: 10.1002/acr.21860.
- Chauhan K, Hart P, Chowdhary V. Immunoglobulin G4 (IgG4) Related Disease. 2012, 73-88. DOI: 10.1007/978-1-4614-5088-7_5.
- Chowdhary VR, Tilahun AY, Clark CR, Grande JP, Rajagopalan G. Chronic Exposure to Staphylococcal Superantigen Elicits a Systemic Inflammatory Disease Mimicking Lupus. The Journal Of Immunology 2012, 189: 2054-2062. PMID: 22798666, PMCID: PMC3462343, DOI: 10.4049/jimmunol.1201097.
- Ludvigsson JF, Rubio-Tapia A, Chowdhary V, Murray JA, Simard JF. Increased Risk of Systemic Lupus Erythematosus in 29,000 Patients with Biopsy-verified Celiac Disease. The Journal Of Rheumatology 2012, 39: 1964-1970. PMID: 22859356, PMCID: PMC3463642, DOI: 10.3899/jrheum.120493.
- Makol A, Watt KD, Chowdhary VR. Autoimmune Hepatitis: A Review of Current Diagnosis and Treatment. Hepatitis Research And Treatment 2011, 2011: 390916. PMID: 21760995, PMCID: PMC3132488, DOI: 10.1155/2011/390916.
- Liang KP, Chowdhary VR, Michet CJ, Miller DV, Sundt TM, Connolly HM, Crowson CS, Matteson EL, Warrington KJ. Noninfectious Ascending Aortitis: A Case Series of 64 Patients. The Journal Of Rheumatology 2009, 36: 2290-2297. PMID: 19648309, DOI: 10.3899/jrheum.090081.
- Chowdhary VR, Crowson CS, Liang KP, Michet CJ, Miller DV, Warrington KJ, Matteson EL. Cardiovascular risk factors and acute-phase response in idiopathic ascending aortitis: a case control study. Arthritis Research & Therapy 2009, 11: r29. PMID: 19250534, PMCID: PMC2688264, DOI: 10.1186/ar2633.
- Chowdhary VR, Crowson CS, Poterucha JJ, Moder KG. Liver Involvement in Systemic Lupus Erythematosus: Case Review of 40 Patients. The Journal Of Rheumatology 2008, 35: 2159-2164. PMID: 18793002, DOI: 10.3899/jrheum.080336.
- Chowdhary V, Kallmes DF, Fulgham J, Meyer F, Matteson EL. Recurrent spells and bilateral internal carotid artery stenosis in a diabetic male: A test of patien‐ce(‐ts). Arthritis & Rheumatism 2007, 57: 1098-1101. PMID: 17665478, DOI: 10.1002/art.22905.
- Chowdhary V, Grande J, Luthra H, David C. Characterization of haemorrhagic pulmonary capillaritis: another manifestation of Pristane-induced lupus. Rheumatology 2007, 46: 1405-1410. PMID: 17576695, DOI: 10.1093/rheumatology/kem117.
- Xue A, Chapoval SP, Finn ES, Chowdhary VR, Marietta EV, Gaffey TA, Pursifull AC, David CS. HLA-DQ8 is a predisposing molecule for detergent enzyme subtilisin BPN′-induced hypersensitivity. Clinical Immunology 2005, 117: 302-315. PMID: 16185928, DOI: 10.1016/j.clim.2005.08.003.
- Finn E, Chapoval S, Xue A, Chowdhary V, Marietta E, Gaffey T, Pursifull A, David C. HLA Class II transgenic mice as models to study the allergenicity of bacterial protease Y217L BPN'. Journal Of Allergy And Clinical Immunology 2004, 113: s141. DOI: 10.1016/j.jaci.2003.12.506.
- Chowdhary V, Wakhlu A, Agarwal A, Misra R. Outcome in juvenile dermatomyositis. Indian Pediatrics 2002, 39: 931-5. PMID: 12428038.
- Paisansinsup T, Deshmukh US, Chowdhary VR, Luthra HS, Fu SM, David CS. HLA Class II Influences the Immune Response and Antibody Diversification to Ro60/Sjögren’s Syndrome-A: Heightened Antibody Responses and Epitope Spreading in Mice Expressing HLA-DR molecules. The Journal Of Immunology 2002, 168: 5876-5884. PMID: 12023392, DOI: 10.4049/jimmunol.168.11.5876.
- Chowdhary V, Aggarwal A, Misra R. Multifocal Tubercular Dactylitis in an Adult. JCR Journal Of Clinical Rheumatology 2002, 8: 35-37. PMID: 17039198, DOI: 10.1097/00124743-200202000-00008.
- Chowdhary V, Nityanand S, Prasad K, Pandey R, Dabadghao S. Sweet's syndrome and Pneumocystis carinii pneumonia: two sequelae of low‐dose cytosine arabinoside therapy in a patient with acute myeloid leukemia. European Journal Of Haematology 2000, 65: 72-73. PMID: 10914942, DOI: 10.1034/j.1600-0609.2000.9c177.x.
- Yale Rheumatology (North Haven)6 Devine StreetFl 2 Ste 2BNorth Haven, CT 06473
- Yale Medicine Rheumatology (Orchard)Orchard Medical Center at St. Raphael’s Campus330 Orchard Street, Fl 3 Ste 300New Haven, CT 06511
- Yale Rheumatology (North Haven)6 Devine StreetFl 2 Ste 2BNorth Haven, CT 06473
- Yale Medicine Rheumatology (Orchard)Orchard Medical Center at St. Raphael’s Campus330 Orchard Street, Fl 3 Ste 300New Haven, CT 06511