Genetic and molecular studies of developmental neuropsychiatric disorders
- Study HIC#:0301024156
- Last Updated:04/19/2024
The purpose of this study is to identify the genetic factors that cause Tourette Syndrome and tics using a family-based approach. This will greatly contribute to our understanding of Tourette Syndrome and may help develop new therapies in the future. This study requires the collection of biological samples and completion of a questionnaire from a child and both biological parents, can be done in-person or remotely, and participation will be compensated with a $100 Amazon gift card. A more detailed description of the study may be found at tourettegenes.org.
- GenderBoth
Contact Us
For more information about this study, including how to volunteer, contact:
Adam Lombroso
- Phone Number: 1-203-677-0842
Help Us Discover!
You can help our team find trials you might be eligible for by creating a volunteer profile in MyChart. To get started, create a volunteer profile, or contact helpusdiscover@yale.edu, or call +18779788343 for more information.
Trial Purpose and Description
The aims of this study are:
1. To elucidate comprehensive clinical phenotypes of subjects with developmental neuropsychiatric disorders associated with cognitive and behavioral impairment. a. In subjects with disorders including autism and autism spectrum disorders, obsessive compulsive disorders, anxiety disorders, personality disorders, and Tourette syndrome and/or related disorders such as chronic vocal or motor tics, and Attention Deficit Hyperactivity Disorder (ADHD).
2. To identify and localize genes that produce susceptibility to these disorders. a. To determine functional and expression patterns of these genes b. To examine the transmission of specific phenotypes
Eligibility Criteria
Subjects who have the diagnosis of a pervasive developmental neuropsychiatric disorders including autism and autism spectrum disorders, obsessive compulsive disorders, anxiety disorders, personality disorders, and Tourette syndrome and/or related disorders such as chronic vocal or motor tics, obsessive-compulsive symptoms such as Trichotillomania (hair pulling) and Attention Deficit Hyperactivity Disorder (ADHD) will be included.
Relatives of affected subjects will also be included
Principal Investigator
- Score: 1
