Walter Kernan, MD
Biography
Walter Kernan, MD, is a primary care physician for adults. As a general internist, he sees patients who have a wide range of illnesses and conditions, including asthma, emphysema, hypertension, anxiety, diabetes, and chronic kidney disease. “I try to advocate for all of my patients who have any kind of physical or psychiatric symptom,” Dr. Kernan says. “They may have high blood pressure or just a mysterious shoulder pain.”
“The opportunity to blend science with the humanistic aspect of medicine attracted me to the profession,” Dr. Kernan says. “I appreciate working in a field that requires a broad knowledge about a lot of different conditions.”
During his medical training, Dr. Kernan developed a particular interest in strokes. “I noticed that patients at risk of their first stroke or who had already suffered from one received highly variable care. This meant that common risk factors, like diabetes, high blood pressure, obesity, poor nutrition, and smoking were treated differently by different doctors.” At the time, physicians were still exploring the science behind stroke to better understand risk factors, Dr. Kernan says. “A high variability among treatment approaches often indicates opportunities for quality improvement,” he says.
Throughout his career, Dr. Kernan has helped lead several clinical trials comparing different stroke treatments. More recently, he has explored the possibility that underlying metabolic diseases—such as pre-diabetes, diabetes, or obesity—in some patients could play an important role in preventing future strokes. “Previous research has shown, for example, that treating pre-diabetes can have a profound impact on future heart attacks and strokes,” Dr. Kernan says.
No matter which condition Dr. Kernan addresses, he listens to any lingering fears a patient may have. “Being ill is a scary experience,” he says. “It threatens your personhood, confidence, and hold on all that you value. So, I build my care around a patient’s values, preferences, and hopes for the future.”
“We need to start early in life to help patients lead healthy lives,” Dr. Kernan says. “The opportunities to do this will flourish in the next few years and primary care will be at the forefront of those efforts.”
Titles
- Professor Emeritus of Medicine (General Medicine)
Education & Training
- BMedSciYale University, Sciencey stuff (2024)
- FellowYale University School of Medicine (1989)
- ResidentJohns Hopkins Hospital (1987)
- MDDartmouth College (1984)
- BAHarvard College (1978)
Languages Spoken
- Català (Catalan)
- English
Additional Information
- Ruth-Marie E. Fincher, MD Service Award: Clerkship Directors in Internal Medicine (2015)
- Alvan R. Feinstein Award: Yale School of medicine (2013)
- Medical Educator Award: Society of General Internal Medicine-New England Region (1996)
- AB of Internal Medicine, Internal Medicine (1987)
- National Institutes of Neurological Disorders and Stroke (2010 - 2012): NST-1 Study Section
- Yale School of Medicine (2006 - 2009): Term Appointments & Promotions Committee
- National Institutes of Neurological Disorders and Stroke (2005 - 2009): NSD-K Study Section
- Yale School of Medicine (2000 - 2011): Part Time Faculty Appointments & Promotions Committee
- Clerkship Directors in Internal Medicine (1999 - 2017): Member
- American Heart Association (1989 - Present): Member
- Society of General Internal Medicine (1988 - Present): Member
- American College of Physicians (1984 - Present): Member
- Rivier C, Acosta J, Leasure A, Forman R, Sharma R, de Havenon A, Spatz E, Inzucchi S, Kernan W, Falcone G, Sheth K. Secondary Prevention in Patients With Stroke Versus Myocardial Infarction: Analysis of 2 National Cohorts. Journal Of The American Heart Association 2024, 13: e033322. PMID: 38639369, DOI: 10.1161/jaha.123.033322.
- Kernan W. The Primary Care Workforce Training Pipeline Has Two Ends. Journal Of General Internal Medicine 2024, 1-2. PMID: 38429483, DOI: 10.1007/s11606-024-08682-1.
- de Havenon A, Viscoli C, Kernan W, Kleindorfer D, Robinson D, Becker C, Sucharew H, Sheth K. Abstract 132: Disability and Enrollment in Secondary Stroke Prevention Trials: Evidence for a New Paradigm of Inclusion. Stroke 2024, 55 DOI: 10.1161/str.55.suppl_1.132.
- Ridha M, McCullough S, viscoli C, Kernan W, Zhang C, Kamel H, Merkler A. Abstract TMP99: Risk of Stroke Recurrence and Silent Myocardial Infarction. Stroke 2024, 55 DOI: 10.1161/str.55.suppl_1.tmp99.
- Forman R, Xin X, Kernan W, Sheth K, Lu Y. Abstract 137: Post-Stroke Blood Pressure Control and Follow Up Care in Real-World Setting. Stroke 2024, 55 DOI: 10.1161/str.55.suppl_1.137.
- Sharma R, de Havenon A, Rivier C, Payabvash S, Forman R, Krumholz H, Falcone G, Sheth K, Kernan W. Impaired mobility and MRI markers of vascular brain injury: Atherosclerosis Risk in Communities and UK Biobank studies. BMJ Neurology Open 2024, 6: e000501. PMID: 38288313, PMCID: PMC10823923, DOI: 10.1136/bmjno-2023-000501.
- Ndumele C, Neeland I, Tuttle K, Chow S, Mathew R, Khan S, Coresh J, Baker-Smith C, Carnethon M, Després J, Ho J, Joseph J, Kernan W, Khera A, Kosiborod M, Lekavich C, Lewis E, Lo K, Ozkan B, Palaniappan L, Patel S, Pencina M, Powell-Wiley T, Sperling L, Virani S, Wright J, Singh R, Elkind M, Rangaswami J, Association O. A Synopsis of the Evidence for the Science and Clinical Management of Cardiovascular-Kidney-Metabolic (CKM) Syndrome: A Scientific Statement From the American Heart Association. Circulation 2023, 148: 1636-1664. PMID: 37807920, DOI: 10.1161/cir.0000000000001186.
- Ndumele C, Rangaswami J, Chow S, Neeland I, Tuttle K, Khan S, Coresh J, Mathew R, Baker-Smith C, Carnethon M, Despres J, Ho J, Joseph J, Kernan W, Khera A, Kosiborod M, Lekavich C, Lewis E, Lo K, Ozkan B, Palaniappan L, Patel S, Pencina M, Powell-Wiley T, Sperling L, Virani S, Wright J, Singh R, Elkind M, Association O. Cardiovascular-Kidney-Metabolic Health: A Presidential Advisory From the American Heart Association. Circulation 2023, 148: 1606-1635. PMID: 37807924, DOI: 10.1161/cir.0000000000001184.
- Balasubramanian P, Kernan W, Sheth K, Ofstad A, Rosenstock J, Wanner C, Zinman B, Mattheus M, Marx N, Inzucchi S. Baseline Cardiovascular Risk Factor Control in Patients With Type 2 Diabetes and Coronary Disease Versus Stroke: Secondary Analysis of Cardiovascular Outcome Trials. Stroke 2023, 54: 2013-2021. PMID: 37449424, PMCID: PMC10358436, DOI: 10.1161/strokeaha.122.042053.
- Dearborn Tomazos J, Viscoli C, Amin H, Lovelett L, Rivera J, Gull A, Kernan W. Partial Meal Replacement for Weight Loss after Stroke: Results of a Pilot Clinical Trial. Cerebrovascular Diseases 2023, 53: 54-61. PMID: 37231793, DOI: 10.1159/000530996.
- Hassan S, Viscoli C, O’Connor P, Dugdale L, Sofair A, Fitz M, Richards B, Feiereisel K, Lee S, Ost S, Swails J, Fishman M, Kernan W. Separate But Not Equal? A Cross-Sectional Study of Segregation by Payor Mix in Academic Primary Care Clinics. Journal Of General Internal Medicine 2023, 38: 2318-2325. PMID: 36800147, PMCID: PMC10406732, DOI: 10.1007/s11606-023-08066-x.
- Sharma R, De Havenon A, Rivier C, Payabvash S, Forman R, Krumholz H, Falcone G, Sheth K, Kernan W. Abstract 131: Brain Mri Biomarkers Of Impaired Balance And Slow Walk Speed: Atherosclerosis Risk In Communities And UK Biobank Studies. Stroke 2023, 54: a131-a131. DOI: 10.1161/str.54.suppl_1.131.
- de Havenon A, Sharma R, Sarpong D, Forman R, Prabhakaran S, Spatz E, Krumholz H, Fernandes C, Roy B, Sheth K, Kernan W. Abstract TMP25: Major Adverse Brain Events: Incidence Rates Of A Novel Composite Vascular Neurologic Outcome. Stroke 2023, 54: atmp25-atmp25. DOI: 10.1161/str.54.suppl_1.tmp25.
- Kernan W, Forman R, Inzucchi S. Caring for Patients With Diabetes in Stroke Neurology. Stroke 2022, 54: 894-904. PMID: 36541212, DOI: 10.1161/strokeaha.122.038163.
- Forman R, Viscoli C, Meurer K, Sheth K, Sansing L, de Havenon A, Sharma R, Mariscal M, Kernan W. Technical Dissonance in Home Blood Pressure Monitoring After Stroke: Having the Machine, but Not Using Correctly. American Journal Of Hypertension 2022, 36: 195-200. PMID: 36520024, PMCID: PMC10016067, DOI: 10.1093/ajh/hpac129.
- Forman R, Viscoli CM, Bath PM, Furie KL, Guarino P, Inzucchi SE, Young L, Kernan WN. Central vs site outcome adjudication in the IRIS trial. Journal Of Stroke And Cerebrovascular Diseases 2022, 31: 106667. PMID: 35901589, DOI: 10.1016/j.jstrokecerebrovasdis.2022.106667.
- Dearborn-Tomazos J, viscoli C, Rivera J, Gull A, Lovelett L, Amin H, Kernan W. Abstract 156: Main Results Of The Take Off Pounds After Stroke Trial. Stroke 2022, 53: a156-a156. DOI: 10.1161/str.53.suppl_1.156.
- Kernan WN. Eating Well to Prevent Stroke. Stroke 2021, 52: 3551-3554. PMID: 34496614, DOI: 10.1161/strokeaha.121.036172.
- Kernan WN, Viera AJ, Billinger SA, Bravata DM, Stark SL, Kasner SE, Kuritzky L, Towfighi A, Arteriosclerosis T. Primary Care of Adult Patients After Stroke: A Scientific Statement From the American Heart Association/American Stroke Association. Stroke 2021, 52: e558-e571. PMID: 34261351, DOI: 10.1161/str.0000000000000382.
- Kiran A, Viscoli CM, Furie KL, Gorman M, Kernan WN. Adherence to study drug in a stroke prevention trial"?>. Journal Of Stroke And Cerebrovascular Diseases 2020, 29: 105048. PMID: 32912514, PMCID: PMC7487071, DOI: 10.1016/j.jstrokecerebrovasdis.2020.105048.
- Endres M, Kernan W. LDL (Low-Density Lipoprotein) Cholesterol Below 70. Stroke 2020, 51: 2276-2278. PMID: 32513094, DOI: 10.1161/strokeaha.120.029429.
- Dearborn JL, Viscoli CM, Young LH, Gorman MJ, Furie KL, Kernan WN. Achievement of Guideline-Recommended Weight Loss Among Patients With Ischemic Stroke and Obesity. Stroke 2019, 50: 713-717. PMID: 30786849, PMCID: PMC6391736, DOI: 10.1161/strokeaha.118.024008.
- INZUCCHI S, VISCOLI C, YOUNG L, GORMAN M, CONWIT R, SCHWARTZ G, KERNAN W. What Mediated Pioglitazone's Cardiovascular (CV) Benefit in the IRIS Trial? Diabetes 2018, 67 DOI: 10.2337/db18-17-lb.
- Kernan WN. Keeping Faith With Patients After Stroke or Transient Ischemic Attack. JAMA Neurology 2018, 75: 404-405. PMID: 29404565, DOI: 10.1001/jamaneurol.2017.4027.
- Dearborn J, Viscoli C, Kernan W. Abstract TP389: Achievement of Healthy Weight Loss Among Patients With Recent Ischemic Stroke or TIA and Obesity. Stroke 2018, 49 DOI: 10.1161/str.49.suppl_1.tp389.
- Kernan WN, Viscoli CM, Dearborn JL, Kent DM, Conwit R, Fayad P, Furie KL, Gorman M, Guarino PD, Inzucchi SE, Stuart A, Young LH. Targeting Pioglitazone Hydrochloride Therapy After Stroke or Transient Ischemic Attack According to Pretreatment Risk for Stroke or Myocardial Infarction. JAMA Neurology 2017, 74: 1319-1327. PMID: 28975241, PMCID: PMC5710663, DOI: 10.1001/jamaneurol.2017.2136.
- Yaghi S, Furie KL, Viscoli CM, Kamel H, Gorman M, Dearborn J, Young LH, Inzucchi SE, Lovejoy AM, Kasner SE, Conwit R, Kernan WN. Pioglitazone Prevents Stroke in Patients With a Recent Transient Ischemic Attack or Ischemic Stroke. Circulation 2017, 137: 455-463. PMID: 29084736, DOI: 10.1161/circulationaha.117.030458.
- Furie KL, Viscoli CM, Gorman M, Ford GA, Young LH, Inzucchi SE, Guarino PD, Lovejoy AM, Conwit R, Tanne D, Kernan WN. Effects of pioglitazone on cognitive function in patients with a recent ischaemic stroke or TIA: a report from the IRIS trial. Journal Of Neurology Neurosurgery & Psychiatry 2017, 89: 21. PMID: 28939682, DOI: 10.1136/jnnp-2017-316361.
- Epstein KA, Viscoli CM, Spence JD, Young LH, Inzucchi SE, Gorman M, Gerstenhaber B, Guarino PD, Dixit A, Furie KL, Kernan WN, Bladin C, Davis S, Wijeratne T, Levi C, Parsons M, Brodtmann A, Ng S, Archer J, Delcourt C, Winder T, Berger L, Boulanger J, Chan R, Spence J, Durocher A, Mackey A, Verreault S, Minuk J, Penn A, Shuaib A, Cote R, Selchen D, Bayer N, Sweet M, Malik S, Stotts G, Griewing B, Soda H, Weinhardt R, Berrouschot J, Stoll A, Witte O, Günther A, Bodechtel U, Schminke U, Hobohm C, Hetzel A, Lambeck J, Wartenberg K, Huttner H, Dittrich R, Nabavi D, Gröschel K, Thomalla G, Rosenkranz M, Jander S, Meisel A, Ludolph A, Althaus K, Huber R, Lorenz M, Tanne D, Merzlyak O, Bornstein N, Telman G, Lampl Y, Streifler J, Weller B, Ifergane G, Wirgin Y, Carolei A, Toni D, Stanzione P, Micieli G, Agnelli G, Caso V, Gandolfo C, Comi G, Consoli D, Rasura M, Di Lazzaro V, Dixit A, Jupp B, Shaw L, Salih I, Esisi B, Power M, Strain W, Elyas S, Manawadu D, Kalra L, O'Brien E, Warburton E, Chatterjee K, Hargroves D, Blight A, Moynihan B, Markus H, Macleod M, Broughton D, Rodgers H, Hlaing T, Muir S, Sajid M, Bath P, Price C, Sekaran L, Vahidassr D, Muir K, McIlmoyle J, Datta P, Davey R, Langhorne P, Stott D, Datta P, England T, Muhidden K, O'Connell J, Majmudar N, Schindler J, Clark W, Sethi P, Rordorf G, Kleindorfer D, Silliman S, Gorman M, Kelly M, Singleton L, Meyer B, Jackson C, Walker J, Ehtisham A, Goodpasture H, Wang D, Fayad P, Cordina S, Naritoku D, Chiu D, Lukovits T, Goddeau R, Clark‐Arbogast R, Leigh R, Wityk R, Pettigrew L, Tayal A, Jarouse J, Friday G, Sen S, Kim A, Johnston S, Elkins J, Barrett A, Leira E, Kelly A, Burgin S, Rempe D, Jacoby M, Hughes D, Majersik J, Skalabrin E, Lee J, Hsu C, Sundararajan S, Slivka A, Minagar A, Alicic R, Geraghty M, Kase C, Lansberg M, Albers G, Dietrich D, Hanna J, Gentile N, Santiago F, Katzan I, Ching M, Sawyer, Warwick T, Yilmaz E, Pedelty L, Schneck M, Coull B, Solenski N, Johnston K, Lee V, Prabhakaran S, Johnson M, Silverman I, Salgado M, Birkhahn R, Strawsburg R, Altafullah I, Cohen D, Zweifler R, Lee Kwen P, Hammer M, Vora N, Tietjen G, Albakri E, Dandapani B, Jickling G, Verro P, Roller M, Hughes R, Simpson J, Vidic T, Lash S, Sigsbee B, Rosenbaum D, Fonzetti P, Fleck J, Goldszmidt A, Alexandrov A, Halsey J, Hart R, Sattin J, Kumar S, Book D, Torbey M, Poock J, King M, Graham G, Sung G, Mirsen T, Dromerick A, Runheim A, Jackson C, Feen E, Reichwein R, Waters M, Amory C, Bernardini G, Bell R, Diamond B, Rosenbaum D, Palestrant D, Segal A, Burger K, Schwartz R, Mitsias P, Kramer J, Kramer J, Robbins D, Silver B, Easton J, Feldmann E, Rymer M, Dorssom J, Ali L, Ovbiagele B, Kirshner H. Smoking cessation and outcome after ischemic stroke or TIA. Neurology 2017, 89: 1723-1729. PMID: 28887378, PMCID: PMC5644463, DOI: 10.1212/wnl.0000000000004524.
- Young LH, Viscoli CM, Curtis JP, Inzucchi SE, Schwartz GG, Lovejoy AM, Furie KL, Gorman MJ, Conwit R, Abbott JD, Jacoby DL, Kolansky DM, Pfau SE, Ling FS, Kernan WN. Cardiac Outcomes After Ischemic Stroke or Transient Ischemic Attack. Circulation 2017, 135: 1882-1893. PMID: 28246237, PMCID: PMC5511545, DOI: 10.1161/circulationaha.116.024863.
- Viscoli CM, Inzucchi SE, Young LH, Insogna KL, Conwit R, Furie KL, Gorman M, Kelly MA, Lovejoy AM, Kernan WN, Investigators F. Pioglitazone and Risk for Bone Fracture: Safety Data From a Randomized Clinical Trial. The Journal Of Clinical Endocrinology & Metabolism 2016, 102: 914-922. PMID: 27935736, PMCID: PMC5460686, DOI: 10.1210/jc.2016-3237.
- Stuart AC, Sico JJ, Viscoli CM, Tayal AH, Inzucchi SE, Ford GA, Furie KL, Cote R, Spence JD, Tanne D, Kernan WN. Taking care of volunteers in a stroke trial: a new assisted-management strategy. Stroke And Vascular Neurology 2016, 1: 108. PMID: 28959471, PMCID: PMC5435205, DOI: 10.1136/svn-2016-000029.
- Viscoli C, Kernan W, Young L. Pioglitazone after Ischemic Stroke or Transient Ischemic Attack. New England Journal Of Medicine 2016, 375: 704. PMID: 27532845, DOI: 10.1056/nejmc1605904.
- Inzucchi SE, Viscoli CM, Young LH, Furie KL, Gorman M, Lovejoy AM, Dagogo-Jack S, Ismail-Beigi F, Korytkowski MT, Pratley RE, Schwartz GG, Kernan WN. Pioglitazone Prevents Diabetes in Patients With Insulin Resistance and Cerebrovascular Disease. Diabetes Care 2016, 39: 1684-92. PMID: 27465265, PMCID: PMC5033078, DOI: 10.2337/dc16-0798.
- Kernan W, Viscoli C, Furie K. Pioglitazone After Ischemic Stroke or Transient Ischemic Attack. Journal Of Vascular Surgery 2016, 64: 260. DOI: 10.1016/j.jvs.2016.05.060.
- Kernan WN, Viscoli CM, Furie KL, Young LH, Inzucchi SE, Gorman M, Guarino PD, Lovejoy AM, Peduzzi PN, Conwit R, Brass LM, Schwartz GG, Adams HP, Berger L, Carolei A, Clark W, Coull B, Ford GA, Kleindorfer D, O'Leary JR, Parsons MW, Ringleb P, Sen S, Spence JD, Tanne D, Wang D, Winder TR. Pioglitazone after Ischemic Stroke or Transient Ischemic Attack. New England Journal Of Medicine 2016, 374: 1321-1331. PMID: 26886418, PMCID: PMC4887756, DOI: 10.1056/nejmoa1506930.
- Pioglitazone after Ischemic Stroke or Transient Ischemic AttackNew England Journal of Medicine 2016;374:1321-1331
- Kernan WN, Elnicki DM, Hauer KE. The Selling of Primary Care 2015. Journal Of General Internal Medicine 2015, 30: 1376-1380. PMID: 26173527, PMCID: PMC4539323, DOI: 10.1007/s11606-015-3364-9.
- Sico J, Viscoli C, Tayal A, Spence D, Ford G, Kernan W. Abstract W P369: International Variability in Stroke Preventive Care. Stroke 2015, 46 DOI: 10.1161/str.46.suppl_1.wp369.
- Kernan WN, Viscoli CM, Varughese MC. Litigation Seeking Access to Data From Ongoing Clinical Trials: A Threat to Clinical Research. JAMA Internal Medicine 2014, 174: 1502-1504. PMID: 25047222, PMCID: PMC5758866, DOI: 10.1001/jamainternmed.2014.3248.
- Kernan WN, Ovbiagele B, Black HR, Bravata DM, Chimowitz MI, Ezekowitz MD, Fang MC, Fisher M, Furie KL, Heck DV, Johnston SC, Kasner SE, Kittner SJ, Mitchell PH, Rich MW, Richardson D, Schwamm LH, Wilson JA. Guidelines for the Prevention of Stroke in Patients With Stroke and Transient Ischemic Attack. Stroke 2014, 45: 2160-2236. PMID: 24788967, DOI: 10.1161/str.0000000000000024.
- Preserving Research Integrity for Participants and the Public: Successful Defense against a Subpoena to Unblind an On-Going NIH TrialJAMA Intern Med 2014;174:1-3
- Zhang Z, Peluso MJ, Gross CP, Viscoli CM, Kernan WN. Adherence reporting in randomized controlled trials. Clinical Trials 2013, 11: 195-204. PMID: 24357665, DOI: 10.1177/1740774513512565.
- Kernan WN. Use of Recruitment Networks in Randomized Trials. Stroke 2013, 44: s119-s121. PMID: 23709705, DOI: 10.1161/strokeaha.111.000694.
- Kernan WN, Inzucchi SE, Sawan C, Macko RF, Furie KL. Obesity. Stroke 2012, 44: 278-286. PMID: 23111440, DOI: 10.1161/strokeaha.111.639922.
- Kernan WN, Inzucchi SE. Metabolic Rehabilitation. Stroke 2011, 42: 3333-3335. PMID: 21998067, PMCID: PMC3226842, DOI: 10.1161/strokeaha.111.632489.
- Kernan W, Viscoli C, Brass L, Amatangelo M, Birch A, Clark W, Conwit R, Furie K, Gorman M, Pesapane B, Kleindorfer D, Lovejoy A, Osborne J, Silliman S, Zweifler R, Horwitz R. Boosting enrolment in clinical trials: validation of a regional network model. Clinical Trials 2011, 8: 645-653. PMID: 21824978, PMCID: PMC3852692, DOI: 10.1177/1740774511414925.
- Durning SJ, Elnicki DM, Cruess DF, Reddy S, Kernan WN, Harrell HE, Schwartz MD, Fagan MJ, Battistone M, Hauer KE. Almost Internists: Analysis of Students Who Considered Internal Medicine but Chose Other Fields. Academic Medicine 2011, 86: 194-200. PMID: 21169784, DOI: 10.1097/acm.0b013e3182045ee5.
- Kernan WN, Launer LJ, Goldstein LB. What Is the Future of Stroke Prevention? Stroke 2010, 41: s35-s38. PMID: 20876501, PMCID: PMC4795938, DOI: 10.1161/strokeaha.110.592022.
- Kernan WN, Viscoli CM, DeMarco D, Mendes B, Shrauger K, Schindler JL, McVeety JC, Sicklick A, Moalli D, Greco P, Bravata DM, Eisen S, Resor L, Sena K, Story D, Brass LM, Furie KL, Gutmann L, Hinnau E, Gorman M, Lovejoy AM, Inzucchi SE, Young LH, Horwitz RI. Boosting enrollment in neurology trials with Local Identification and Outreach Networks (LIONs). Neurology 2009, 72: 1345-1351. PMID: 19365056, PMCID: PMC2677492, DOI: 10.1212/wnl.0b013e3181a0fda3.
- Hauer KE, Durning SJ, Kernan WN, Fagan MJ, Mintz M, O’Sullivan P, Battistone M, DeFer T, Elnicki M, Harrell H, Reddy S, Boscardin CK, Schwartz MD. Factors Associated With Medical Students' Career Choices Regarding Internal Medicine. JAMA 2008, 300: 1154-1164. PMID: 18780844, DOI: 10.1001/jama.300.10.1154.
- Hauer KE, Fagan MJ, Kernan W, Mintz M, Durning SJ. Internal Medicine Clerkship Directors’ Perceptions About Student Interest in Internal Medicine Careers. Journal Of General Internal Medicine 2008, 23: 1101-1104. PMID: 18612752, PMCID: PMC2517945, DOI: 10.1007/s11606-008-0640-y.
- Kernan WN, Hershman W, Alper EJ, Lee MY, Viscoli CM, Perry JR, O'Connor PG. Disagreement Between Students and Preceptors Regarding the Value of Teaching Behaviors for Ambulatory Care Settings. Teaching And Learning In Medicine 2008, 20: 143-150. PMID: 18444201, DOI: 10.1080/10401330801991667.
- Kernan WN, Schindler JL. Rapid intervention for TIA: a new standard emerges. The Lancet Neurology 2007, 6: 940-941. PMID: 17928271, DOI: 10.1016/s1474-4422(07)70249-1.
- Kernan WN. Stroke after transient ischaemic attack: dealing in futures. The Lancet 2007, 369: 251-252. PMID: 17258647, DOI: 10.1016/s0140-6736(07)60121-4.
- Yaggi HK, Concato J, Kernan WN, Lichtman JH, Brass LM, Mohsenin V. Obstructive Sleep Apnea as a Risk Factor for Stroke and Death. New England Journal Of Medicine 2005, 353: 2034-2041. PMID: 16282178, DOI: 10.1056/nejmoa043104.
- Rosenbaum JR, Wells CK, Viscoli CM, Brass LM, Kernan WN, Horwitz RI. Altruism as a reason for participation in clinical trials was independently associated with adherence. Journal Of Clinical Epidemiology 2005, 58: 1109-1114. PMID: 16223653, DOI: 10.1016/j.jclinepi.2005.03.014.
- Feldmann E, Broderick JP, Kernan WN, Viscoli CM, Brass LM, Brott T, Morgenstern LB, Wilterdink JL, Horwitz RI. Major Risk Factors for Intracerebral Hemorrhage in the Young Are Modifiable. Stroke 2005, 36: 1881-1885. PMID: 16081867, DOI: 10.1161/01.str.0000177480.62341.6b.
- Bravata DM, Wells CK, Kernan WN, Concato J, Brass LM, Gulanski BI. Association between Impaired Insulin Sensitivity and Stroke. Neuroepidemiology 2005, 25: 69-74. PMID: 15947493, DOI: 10.1159/000086286.
- Bravata DM, Wells CK, Gulanski B, Kernan WN, Brass LM, Long J, Concato J. Racial Disparities in Stroke Risk Factors. Stroke 2005, 36: 1507-1511. PMID: 15961710, DOI: 10.1161/01.str.0000170991.63594.b6.
- Kernan WN, Quagliarello V, Green ML. Student faculty rounds: a peer-mediated learning activity for internal medicine clerkships. Medical Teacher 2005, 27: 140-144. PMID: 16019334, DOI: 10.1080/01421590500047047.
- Viscoli CM, Brass LM, Kernan WN, Sarrel PM, Suissa S, Horwitz RI. Estrogen therapy and risk of cognitive decline: Results from the Women's Estrogen for Stroke Trial (WEST). American Journal Of Obstetrics And Gynecology 2005, 192: 387-393. PMID: 15695976, DOI: 10.1016/j.ajog.2004.08.017.
- Kernan WN, Viscoli CM, Brass LM, Gill TM, Sarrel PM, Horwitz RI. Decline in Physical Performance Among Women With a Recent Transient Ischemic Attack or Ischemic Stroke. Stroke 2005, 36: 630-634. PMID: 15677573, DOI: 10.1161/01.str.0000155728.42847.de.
- Kernan WN, Viscoli CM, Inzucchi SE, Brass LM, Bravata DM, Shulman GI, McVeety JC. Prevalence of Abnormal Glucose Tolerance Following a Transient Ischemic Attack or Ischemic Stroke. JAMA Internal Medicine 2005, 165: 227-233. PMID: 15668371, DOI: 10.1001/archinte.165.2.227.
- Kernan WN, Inzucchi SE. Type 2 diabetes mellitus and insulin resistance: Stroke prevention and management. Current Treatment Options In Neurology 2004, 6: 443-450. PMID: 15461922, DOI: 10.1007/s11940-004-0002-y.
- Bravata DM, Wells CK, Concato J, Kernan WN, Brass LM, Gulanski BI. Two measures of insulin sensitivity provided similar information in a U.S. population. Journal Of Clinical Epidemiology 2004, 57: 1214-1217. PMID: 15567640, DOI: 10.1016/j.jclinepi.2004.05.001.
- Kernan WN, Fagan MJ, Elnicki D, Council C. The clerkship directors in internal medicine's agenda for advancing medical student education in internal medicine. The American Journal Of Medicine 2004, 117: 713-717. PMID: 15501217, DOI: 10.1016/j.amjmed.2004.08.008.
- Kernan WN, Holmboe E, O'Connor PG. Assessing the Teaching Behaviors of Ambulatory Care Preceptors. Academic Medicine 2004, 79: 1088-1094. PMID: 15504778, DOI: 10.1097/00001888-200411000-00017.
- Kernan W. Abstracts From the Proceedings of the 2003 CDIM (Clerkship Directors of Internal Medicine) Annual Meeting. Teaching And Learning In Medicine 2004, 16: 296-300. DOI: 10.1207/s15328015tlm1603_14.
- Kernan WN. Re: Evaluation of acute candesartan cilexetil therapy in stroke survivors. Stroke 2003, 34: e237-8; author reply e237-8. PMID: 14631078, DOI: 10.1161/01.str.0000104158.59498.bc.
- Kernan W, Brass L, Viscoli C, Broderick J, Brott T, Feldmann E, Wilterdink J, Morgenstern L. Use of Ephedra-containing products and risk for hemorrhagic stroke. Neurology 2003, 61: 725. PMID: 12963785, DOI: 10.1212/wnl.61.5.724.
- Green ML, Gross CP, Kernan WN, Wong JG, Holmboe ES. Integrating Teaching Skills and Clinical Content in a Faculty Development Workshop. Journal Of General Internal Medicine 2003, 18: 468-474. PMID: 12823654, PMCID: PMC1494873, DOI: 10.1046/j.1525-1497.2003.20933.x.
- Broderick JP, Viscoli CM, Brott T, Kernan WN, Brass LM, Feldmann E, Morgenstern LB, Wilterdink JL, Horwitz RI. Major Risk Factors for Aneurysmal Subarachnoid Hemorrhage in the Young Are Modifiable. Stroke 2003, 34: 1375-1381. PMID: 12764233, DOI: 10.1161/01.str.0000074572.91827.f4.
- Kernan WN, Inzucchi SE, Viscoli CM, Brass LM, Bravata DM, Shulman GI, McVeety JC, Horwitz RI. Impaired insulin sensitivity among nondiabetic patients with a recent TIA or ischemic stroke. Neurology 2003, 60: 1447-1451. PMID: 12743229, DOI: 10.1212/01.wnl.0000063318.66140.a3.
- Kernan WN, Inzucchi SE, Viscoli CM, Brass LM, Bravata DM, Shulman GI, McVeety JC, Horwitz RI. Pioglitazone Improves Insulin Sensitivity Among Nondiabetic Patients With a Recent Transient Ischemic Attack or Ischemic Stroke. Stroke 2003, 34: 1431-1436. PMID: 12730556, DOI: 10.1161/01.str.0000071108.00234.0e.
- Corbie-Smith G, Viscoli CM, Kernan WN, Brass LM, Sarrel P, Horwitz RI. Influence of race, clinical, and other socio-demographic features on trial participation. Journal Of Clinical Epidemiology 2003, 56: 304-309. PMID: 12767406, DOI: 10.1016/s0895-4356(03)00046-5.
- Morgenstern LB, Viscoli CM, Kernan WN, Brass LM, Broderick JP, Feldmann E, Wilterdink JL, Brott T, Horwitz RI. Use of Ephedra-containing products and risk for hemorrhagic stroke. Neurology 2003, 60: 132-135. PMID: 12525737, DOI: 10.1212/01.wnl.0000042092.20411.5b.
- Kernan WN, Inzucchi SE, Viscoli CM, Brass LM, Bravata DM, Horwitz RI. Insulin resistance and risk for stroke. Neurology 2002, 59: 809-815. PMID: 12349850, DOI: 10.1212/wnl.59.6.809.
- Owens PL, Bradley EH, Horwitz SM, Viscoli CM, Kernan WN, Brass LM, Sarrel PM, Horwitz RI. Clinical assessment of function among women with a recent cerebrovascular event: a self-reported versus performance-based measure. Annals Of Internal Medicine 2002, 136: 802-11. PMID: 12044128, DOI: 10.7326/0003-4819-136-11-200206040-00008.
- Viscoli C, Brass L, Kernan W, Sarrel P, Suissa S, Horwitz R. A Clinical Trial of Estrogen-Replacement Therapy After Ischemic Stroke. Obstetrical & Gynecological Survey 2002, 57: 164-165. DOI: 10.1097/00006254-200203000-00019.
- Viscoli C, Brass L, Kernan W, Sarrel P, Suissa S, Horwitz R. A Clinical Trial of Estrogen-Replacement Therapy after Ischemic Stroke. New England Journal Of Medicine 2001, 345: 1243-1249. PMID: 11680444, DOI: 10.1056/nejmoa010534.
- Hamedani A, Wells C, Brass L, Kernan W, Viscoli C, Maraire J, Awad I, Horwitz R. A Quality-of-Life Instrument for Young Hemorrhagic Stroke Patients. Stroke 2001, 32: 687-695. PMID: 11239188, DOI: 10.1161/01.str.32.3.687.
- Kernan W, Makuch R. Response. Journal Of Clinical Epidemiology 2001, 54: 105. DOI: 10.1016/s0895-4356(00)00285-7.
- Kernan W, Viscoli C, Brass L, Broderick J, Brott T, Feldmann E, Morgenstern L, Wilterdink J, Horwitz R. Phenylpropanolamine and the Risk of Hemorrhagic Stroke. New England Journal Of Medicine 2000, 343: 1826-1832. PMID: 11117973, DOI: 10.1056/nejm200012213432501.
- Kernan W, Lee M, Stone S, Freudigman K, O’Connor P. Effective teaching for preceptors of ambulatory care: a survey of medical students. The American Journal Of Medicine 2000, 108: 499-502. PMID: 10781784, DOI: 10.1016/s0002-9343(00)00301-6.
- Kernan W, Viscoli C, Brass L, Makuch R, Sarrel P, Horwitz R. Blood Pressure Exceeding National Guidelines Among Women After Stroke. Stroke 2000, 31: 415-419. PMID: 10657415, DOI: 10.1161/01.str.31.2.415.
- Kernan W, Viscoli C, Brass L, Makuch R, Sarrel P, Roberts R, Gent M, Rothwell P, Sacco R, Liu R, Boden-Albala B, Horwitz R. The Stroke Prognosis Instrument II (SPI-II). Stroke 2000, 31: 456-462. PMID: 10657422, DOI: 10.1161/01.str.31.2.456.
- Kernan W, Viscoli C, Makuch R, Brass L, Horwitz R. Stratified Randomization for Clinical Trials. Journal Of Clinical Epidemiology 1999, 52: 19-26. PMID: 9973070, DOI: 10.1016/s0895-4356(98)00138-3.
- Kernan W, Brass L, Viscoli C, Sarrel P, Makuch R, Horwitz R. Estrogen after ischemic stroke: Clinical basis and design of The Women's Estrogen for Stroke Trial. Journal Of Stroke And Cerebrovascular Diseases 1998, 7: 85-95. PMID: 17895061, DOI: 10.1016/s1052-3057(98)80026-8.
- Kernan W, O'Connor P. Site accommodations and preceptor behaviors valued by 3rd‐year students in ambulatory internal medicine clerkships. Teaching And Learning In Medicine 1997, 9: 96-102. DOI: 10.1080/10401339709539822.
- Kernan W, Goroll A. A strategy for precepting medical students in ambulatory settings. Connecticut Medicine 1996, 60: 203-9. PMID: 8776123.
- Kernan W, Castellsague J, Perlman G, Ostfeld A. Incidence of hospitalization for digitalis toxicity among elderly Americans. The American Journal Of Medicine 1994, 96: 426-431. PMID: 8192174, DOI: 10.1016/0002-9343(94)90169-4.
- Kernan W, Horwitz R, Brass L, Viscoli C. Gender difference in prognosis after transient cerebral ischemia or minor stroke. Journal Of Stroke And Cerebrovascular Diseases 1994, 4: 148-154. PMID: 26486051, DOI: 10.1016/s1052-3057(10)80177-6.
- Kernan W, Feinstein A, Brass L. A methodological appraisal of research on prognosis after transient ischemic attacks. Stroke 1991, 22: 1108-1116. PMID: 1926253, DOI: 10.1161/01.str.22.9.1108.
- Kernan WN, Horwitz RI, Brass LM, Viscoli CM, Taylor KJ. A prognostic system for transient ischemia or minor stroke. Annals Of Internal Medicine 1991, 114: 552-7. PMID: 2001088, DOI: 10.7326/0003-4819-114-7-552.
- Burnand B, Kernan W, Feinstein A. Indexes and boundaries for “quantitative significance” in statistical decisions. Journal Of Clinical Epidemiology 1990, 43: 1273-1284. PMID: 2254764, DOI: 10.1016/0895-4356(90)90093-5.
- Brass L, Kernan W. Canadian Neurological Scale. Neurology 1989, 39: 1556-8. PMID: 2812344, DOI: 10.1212/wnl.39.11.1556.
Biography
Walter Kernan, MD, is a primary care physician for adults. As a general internist, he sees patients who have a wide range of illnesses and conditions, including asthma, emphysema, hypertension, anxiety, diabetes, and chronic kidney disease. “I try to advocate for all of my patients who have any kind of physical or psychiatric symptom,” Dr. Kernan says. “They may have high blood pressure or just a mysterious shoulder pain.”
“The opportunity to blend science with the humanistic aspect of medicine attracted me to the profession,” Dr. Kernan says. “I appreciate working in a field that requires a broad knowledge about a lot of different conditions.”
During his medical training, Dr. Kernan developed a particular interest in strokes. “I noticed that patients at risk of their first stroke or who had already suffered from one received highly variable care. This meant that common risk factors, like diabetes, high blood pressure, obesity, poor nutrition, and smoking were treated differently by different doctors.” At the time, physicians were still exploring the science behind stroke to better understand risk factors, Dr. Kernan says. “A high variability among treatment approaches often indicates opportunities for quality improvement,” he says.
Throughout his career, Dr. Kernan has helped lead several clinical trials comparing different stroke treatments. More recently, he has explored the possibility that underlying metabolic diseases—such as pre-diabetes, diabetes, or obesity—in some patients could play an important role in preventing future strokes. “Previous research has shown, for example, that treating pre-diabetes can have a profound impact on future heart attacks and strokes,” Dr. Kernan says.
No matter which condition Dr. Kernan addresses, he listens to any lingering fears a patient may have. “Being ill is a scary experience,” he says. “It threatens your personhood, confidence, and hold on all that you value. So, I build my care around a patient’s values, preferences, and hopes for the future.”
“We need to start early in life to help patients lead healthy lives,” Dr. Kernan says. “The opportunities to do this will flourish in the next few years and primary care will be at the forefront of those efforts.”
Titles
- Professor Emeritus of Medicine (General Medicine)
Education & Training
- BMedSciYale University, Sciencey stuff (2024)
- FellowYale University School of Medicine (1989)
- ResidentJohns Hopkins Hospital (1987)
- MDDartmouth College (1984)
- BAHarvard College (1978)
Languages Spoken
- Català (Catalan)
- English
Additional Information
- Ruth-Marie E. Fincher, MD Service Award: Clerkship Directors in Internal Medicine (2015)
- Alvan R. Feinstein Award: Yale School of medicine (2013)
- Medical Educator Award: Society of General Internal Medicine-New England Region (1996)
- AB of Internal Medicine, Internal Medicine (1987)
- National Institutes of Neurological Disorders and Stroke (2010 - 2012): NST-1 Study Section
- Yale School of Medicine (2006 - 2009): Term Appointments & Promotions Committee
- National Institutes of Neurological Disorders and Stroke (2005 - 2009): NSD-K Study Section
- Yale School of Medicine (2000 - 2011): Part Time Faculty Appointments & Promotions Committee
- Clerkship Directors in Internal Medicine (1999 - 2017): Member
- American Heart Association (1989 - Present): Member
- Society of General Internal Medicine (1988 - Present): Member
- American College of Physicians (1984 - Present): Member
- Rivier C, Acosta J, Leasure A, Forman R, Sharma R, de Havenon A, Spatz E, Inzucchi S, Kernan W, Falcone G, Sheth K. Secondary Prevention in Patients With Stroke Versus Myocardial Infarction: Analysis of 2 National Cohorts. Journal Of The American Heart Association 2024, 13: e033322. PMID: 38639369, DOI: 10.1161/jaha.123.033322.
- Kernan W. The Primary Care Workforce Training Pipeline Has Two Ends. Journal Of General Internal Medicine 2024, 1-2. PMID: 38429483, DOI: 10.1007/s11606-024-08682-1.
- de Havenon A, Viscoli C, Kernan W, Kleindorfer D, Robinson D, Becker C, Sucharew H, Sheth K. Abstract 132: Disability and Enrollment in Secondary Stroke Prevention Trials: Evidence for a New Paradigm of Inclusion. Stroke 2024, 55 DOI: 10.1161/str.55.suppl_1.132.
- Ridha M, McCullough S, viscoli C, Kernan W, Zhang C, Kamel H, Merkler A. Abstract TMP99: Risk of Stroke Recurrence and Silent Myocardial Infarction. Stroke 2024, 55 DOI: 10.1161/str.55.suppl_1.tmp99.
- Forman R, Xin X, Kernan W, Sheth K, Lu Y. Abstract 137: Post-Stroke Blood Pressure Control and Follow Up Care in Real-World Setting. Stroke 2024, 55 DOI: 10.1161/str.55.suppl_1.137.
- Sharma R, de Havenon A, Rivier C, Payabvash S, Forman R, Krumholz H, Falcone G, Sheth K, Kernan W. Impaired mobility and MRI markers of vascular brain injury: Atherosclerosis Risk in Communities and UK Biobank studies. BMJ Neurology Open 2024, 6: e000501. PMID: 38288313, PMCID: PMC10823923, DOI: 10.1136/bmjno-2023-000501.
- Ndumele C, Neeland I, Tuttle K, Chow S, Mathew R, Khan S, Coresh J, Baker-Smith C, Carnethon M, Després J, Ho J, Joseph J, Kernan W, Khera A, Kosiborod M, Lekavich C, Lewis E, Lo K, Ozkan B, Palaniappan L, Patel S, Pencina M, Powell-Wiley T, Sperling L, Virani S, Wright J, Singh R, Elkind M, Rangaswami J, Association O. A Synopsis of the Evidence for the Science and Clinical Management of Cardiovascular-Kidney-Metabolic (CKM) Syndrome: A Scientific Statement From the American Heart Association. Circulation 2023, 148: 1636-1664. PMID: 37807920, DOI: 10.1161/cir.0000000000001186.
- Ndumele C, Rangaswami J, Chow S, Neeland I, Tuttle K, Khan S, Coresh J, Mathew R, Baker-Smith C, Carnethon M, Despres J, Ho J, Joseph J, Kernan W, Khera A, Kosiborod M, Lekavich C, Lewis E, Lo K, Ozkan B, Palaniappan L, Patel S, Pencina M, Powell-Wiley T, Sperling L, Virani S, Wright J, Singh R, Elkind M, Association O. Cardiovascular-Kidney-Metabolic Health: A Presidential Advisory From the American Heart Association. Circulation 2023, 148: 1606-1635. PMID: 37807924, DOI: 10.1161/cir.0000000000001184.
- Balasubramanian P, Kernan W, Sheth K, Ofstad A, Rosenstock J, Wanner C, Zinman B, Mattheus M, Marx N, Inzucchi S. Baseline Cardiovascular Risk Factor Control in Patients With Type 2 Diabetes and Coronary Disease Versus Stroke: Secondary Analysis of Cardiovascular Outcome Trials. Stroke 2023, 54: 2013-2021. PMID: 37449424, PMCID: PMC10358436, DOI: 10.1161/strokeaha.122.042053.
- Dearborn Tomazos J, Viscoli C, Amin H, Lovelett L, Rivera J, Gull A, Kernan W. Partial Meal Replacement for Weight Loss after Stroke: Results of a Pilot Clinical Trial. Cerebrovascular Diseases 2023, 53: 54-61. PMID: 37231793, DOI: 10.1159/000530996.
- Hassan S, Viscoli C, O’Connor P, Dugdale L, Sofair A, Fitz M, Richards B, Feiereisel K, Lee S, Ost S, Swails J, Fishman M, Kernan W. Separate But Not Equal? A Cross-Sectional Study of Segregation by Payor Mix in Academic Primary Care Clinics. Journal Of General Internal Medicine 2023, 38: 2318-2325. PMID: 36800147, PMCID: PMC10406732, DOI: 10.1007/s11606-023-08066-x.
- Sharma R, De Havenon A, Rivier C, Payabvash S, Forman R, Krumholz H, Falcone G, Sheth K, Kernan W. Abstract 131: Brain Mri Biomarkers Of Impaired Balance And Slow Walk Speed: Atherosclerosis Risk In Communities And UK Biobank Studies. Stroke 2023, 54: a131-a131. DOI: 10.1161/str.54.suppl_1.131.
- de Havenon A, Sharma R, Sarpong D, Forman R, Prabhakaran S, Spatz E, Krumholz H, Fernandes C, Roy B, Sheth K, Kernan W. Abstract TMP25: Major Adverse Brain Events: Incidence Rates Of A Novel Composite Vascular Neurologic Outcome. Stroke 2023, 54: atmp25-atmp25. DOI: 10.1161/str.54.suppl_1.tmp25.
- Kernan W, Forman R, Inzucchi S. Caring for Patients With Diabetes in Stroke Neurology. Stroke 2022, 54: 894-904. PMID: 36541212, DOI: 10.1161/strokeaha.122.038163.
- Forman R, Viscoli C, Meurer K, Sheth K, Sansing L, de Havenon A, Sharma R, Mariscal M, Kernan W. Technical Dissonance in Home Blood Pressure Monitoring After Stroke: Having the Machine, but Not Using Correctly. American Journal Of Hypertension 2022, 36: 195-200. PMID: 36520024, PMCID: PMC10016067, DOI: 10.1093/ajh/hpac129.
- Forman R, Viscoli CM, Bath PM, Furie KL, Guarino P, Inzucchi SE, Young L, Kernan WN. Central vs site outcome adjudication in the IRIS trial. Journal Of Stroke And Cerebrovascular Diseases 2022, 31: 106667. PMID: 35901589, DOI: 10.1016/j.jstrokecerebrovasdis.2022.106667.
- Dearborn-Tomazos J, viscoli C, Rivera J, Gull A, Lovelett L, Amin H, Kernan W. Abstract 156: Main Results Of The Take Off Pounds After Stroke Trial. Stroke 2022, 53: a156-a156. DOI: 10.1161/str.53.suppl_1.156.
- Kernan WN. Eating Well to Prevent Stroke. Stroke 2021, 52: 3551-3554. PMID: 34496614, DOI: 10.1161/strokeaha.121.036172.
- Kernan WN, Viera AJ, Billinger SA, Bravata DM, Stark SL, Kasner SE, Kuritzky L, Towfighi A, Arteriosclerosis T. Primary Care of Adult Patients After Stroke: A Scientific Statement From the American Heart Association/American Stroke Association. Stroke 2021, 52: e558-e571. PMID: 34261351, DOI: 10.1161/str.0000000000000382.
- Kiran A, Viscoli CM, Furie KL, Gorman M, Kernan WN. Adherence to study drug in a stroke prevention trial"?>. Journal Of Stroke And Cerebrovascular Diseases 2020, 29: 105048. PMID: 32912514, PMCID: PMC7487071, DOI: 10.1016/j.jstrokecerebrovasdis.2020.105048.
- Endres M, Kernan W. LDL (Low-Density Lipoprotein) Cholesterol Below 70. Stroke 2020, 51: 2276-2278. PMID: 32513094, DOI: 10.1161/strokeaha.120.029429.
- Dearborn JL, Viscoli CM, Young LH, Gorman MJ, Furie KL, Kernan WN. Achievement of Guideline-Recommended Weight Loss Among Patients With Ischemic Stroke and Obesity. Stroke 2019, 50: 713-717. PMID: 30786849, PMCID: PMC6391736, DOI: 10.1161/strokeaha.118.024008.
- INZUCCHI S, VISCOLI C, YOUNG L, GORMAN M, CONWIT R, SCHWARTZ G, KERNAN W. What Mediated Pioglitazone's Cardiovascular (CV) Benefit in the IRIS Trial? Diabetes 2018, 67 DOI: 10.2337/db18-17-lb.
- Kernan WN. Keeping Faith With Patients After Stroke or Transient Ischemic Attack. JAMA Neurology 2018, 75: 404-405. PMID: 29404565, DOI: 10.1001/jamaneurol.2017.4027.
- Dearborn J, Viscoli C, Kernan W. Abstract TP389: Achievement of Healthy Weight Loss Among Patients With Recent Ischemic Stroke or TIA and Obesity. Stroke 2018, 49 DOI: 10.1161/str.49.suppl_1.tp389.
- Kernan WN, Viscoli CM, Dearborn JL, Kent DM, Conwit R, Fayad P, Furie KL, Gorman M, Guarino PD, Inzucchi SE, Stuart A, Young LH. Targeting Pioglitazone Hydrochloride Therapy After Stroke or Transient Ischemic Attack According to Pretreatment Risk for Stroke or Myocardial Infarction. JAMA Neurology 2017, 74: 1319-1327. PMID: 28975241, PMCID: PMC5710663, DOI: 10.1001/jamaneurol.2017.2136.
- Yaghi S, Furie KL, Viscoli CM, Kamel H, Gorman M, Dearborn J, Young LH, Inzucchi SE, Lovejoy AM, Kasner SE, Conwit R, Kernan WN. Pioglitazone Prevents Stroke in Patients With a Recent Transient Ischemic Attack or Ischemic Stroke. Circulation 2017, 137: 455-463. PMID: 29084736, DOI: 10.1161/circulationaha.117.030458.
- Furie KL, Viscoli CM, Gorman M, Ford GA, Young LH, Inzucchi SE, Guarino PD, Lovejoy AM, Conwit R, Tanne D, Kernan WN. Effects of pioglitazone on cognitive function in patients with a recent ischaemic stroke or TIA: a report from the IRIS trial. Journal Of Neurology Neurosurgery & Psychiatry 2017, 89: 21. PMID: 28939682, DOI: 10.1136/jnnp-2017-316361.
- Epstein KA, Viscoli CM, Spence JD, Young LH, Inzucchi SE, Gorman M, Gerstenhaber B, Guarino PD, Dixit A, Furie KL, Kernan WN, Bladin C, Davis S, Wijeratne T, Levi C, Parsons M, Brodtmann A, Ng S, Archer J, Delcourt C, Winder T, Berger L, Boulanger J, Chan R, Spence J, Durocher A, Mackey A, Verreault S, Minuk J, Penn A, Shuaib A, Cote R, Selchen D, Bayer N, Sweet M, Malik S, Stotts G, Griewing B, Soda H, Weinhardt R, Berrouschot J, Stoll A, Witte O, Günther A, Bodechtel U, Schminke U, Hobohm C, Hetzel A, Lambeck J, Wartenberg K, Huttner H, Dittrich R, Nabavi D, Gröschel K, Thomalla G, Rosenkranz M, Jander S, Meisel A, Ludolph A, Althaus K, Huber R, Lorenz M, Tanne D, Merzlyak O, Bornstein N, Telman G, Lampl Y, Streifler J, Weller B, Ifergane G, Wirgin Y, Carolei A, Toni D, Stanzione P, Micieli G, Agnelli G, Caso V, Gandolfo C, Comi G, Consoli D, Rasura M, Di Lazzaro V, Dixit A, Jupp B, Shaw L, Salih I, Esisi B, Power M, Strain W, Elyas S, Manawadu D, Kalra L, O'Brien E, Warburton E, Chatterjee K, Hargroves D, Blight A, Moynihan B, Markus H, Macleod M, Broughton D, Rodgers H, Hlaing T, Muir S, Sajid M, Bath P, Price C, Sekaran L, Vahidassr D, Muir K, McIlmoyle J, Datta P, Davey R, Langhorne P, Stott D, Datta P, England T, Muhidden K, O'Connell J, Majmudar N, Schindler J, Clark W, Sethi P, Rordorf G, Kleindorfer D, Silliman S, Gorman M, Kelly M, Singleton L, Meyer B, Jackson C, Walker J, Ehtisham A, Goodpasture H, Wang D, Fayad P, Cordina S, Naritoku D, Chiu D, Lukovits T, Goddeau R, Clark‐Arbogast R, Leigh R, Wityk R, Pettigrew L, Tayal A, Jarouse J, Friday G, Sen S, Kim A, Johnston S, Elkins J, Barrett A, Leira E, Kelly A, Burgin S, Rempe D, Jacoby M, Hughes D, Majersik J, Skalabrin E, Lee J, Hsu C, Sundararajan S, Slivka A, Minagar A, Alicic R, Geraghty M, Kase C, Lansberg M, Albers G, Dietrich D, Hanna J, Gentile N, Santiago F, Katzan I, Ching M, Sawyer, Warwick T, Yilmaz E, Pedelty L, Schneck M, Coull B, Solenski N, Johnston K, Lee V, Prabhakaran S, Johnson M, Silverman I, Salgado M, Birkhahn R, Strawsburg R, Altafullah I, Cohen D, Zweifler R, Lee Kwen P, Hammer M, Vora N, Tietjen G, Albakri E, Dandapani B, Jickling G, Verro P, Roller M, Hughes R, Simpson J, Vidic T, Lash S, Sigsbee B, Rosenbaum D, Fonzetti P, Fleck J, Goldszmidt A, Alexandrov A, Halsey J, Hart R, Sattin J, Kumar S, Book D, Torbey M, Poock J, King M, Graham G, Sung G, Mirsen T, Dromerick A, Runheim A, Jackson C, Feen E, Reichwein R, Waters M, Amory C, Bernardini G, Bell R, Diamond B, Rosenbaum D, Palestrant D, Segal A, Burger K, Schwartz R, Mitsias P, Kramer J, Kramer J, Robbins D, Silver B, Easton J, Feldmann E, Rymer M, Dorssom J, Ali L, Ovbiagele B, Kirshner H. Smoking cessation and outcome after ischemic stroke or TIA. Neurology 2017, 89: 1723-1729. PMID: 28887378, PMCID: PMC5644463, DOI: 10.1212/wnl.0000000000004524.
- Young LH, Viscoli CM, Curtis JP, Inzucchi SE, Schwartz GG, Lovejoy AM, Furie KL, Gorman MJ, Conwit R, Abbott JD, Jacoby DL, Kolansky DM, Pfau SE, Ling FS, Kernan WN. Cardiac Outcomes After Ischemic Stroke or Transient Ischemic Attack. Circulation 2017, 135: 1882-1893. PMID: 28246237, PMCID: PMC5511545, DOI: 10.1161/circulationaha.116.024863.
- Viscoli CM, Inzucchi SE, Young LH, Insogna KL, Conwit R, Furie KL, Gorman M, Kelly MA, Lovejoy AM, Kernan WN, Investigators F. Pioglitazone and Risk for Bone Fracture: Safety Data From a Randomized Clinical Trial. The Journal Of Clinical Endocrinology & Metabolism 2016, 102: 914-922. PMID: 27935736, PMCID: PMC5460686, DOI: 10.1210/jc.2016-3237.
- Stuart AC, Sico JJ, Viscoli CM, Tayal AH, Inzucchi SE, Ford GA, Furie KL, Cote R, Spence JD, Tanne D, Kernan WN. Taking care of volunteers in a stroke trial: a new assisted-management strategy. Stroke And Vascular Neurology 2016, 1: 108. PMID: 28959471, PMCID: PMC5435205, DOI: 10.1136/svn-2016-000029.
- Viscoli C, Kernan W, Young L. Pioglitazone after Ischemic Stroke or Transient Ischemic Attack. New England Journal Of Medicine 2016, 375: 704. PMID: 27532845, DOI: 10.1056/nejmc1605904.
- Inzucchi SE, Viscoli CM, Young LH, Furie KL, Gorman M, Lovejoy AM, Dagogo-Jack S, Ismail-Beigi F, Korytkowski MT, Pratley RE, Schwartz GG, Kernan WN. Pioglitazone Prevents Diabetes in Patients With Insulin Resistance and Cerebrovascular Disease. Diabetes Care 2016, 39: 1684-92. PMID: 27465265, PMCID: PMC5033078, DOI: 10.2337/dc16-0798.
- Kernan W, Viscoli C, Furie K. Pioglitazone After Ischemic Stroke or Transient Ischemic Attack. Journal Of Vascular Surgery 2016, 64: 260. DOI: 10.1016/j.jvs.2016.05.060.
- Kernan WN, Viscoli CM, Furie KL, Young LH, Inzucchi SE, Gorman M, Guarino PD, Lovejoy AM, Peduzzi PN, Conwit R, Brass LM, Schwartz GG, Adams HP, Berger L, Carolei A, Clark W, Coull B, Ford GA, Kleindorfer D, O'Leary JR, Parsons MW, Ringleb P, Sen S, Spence JD, Tanne D, Wang D, Winder TR. Pioglitazone after Ischemic Stroke or Transient Ischemic Attack. New England Journal Of Medicine 2016, 374: 1321-1331. PMID: 26886418, PMCID: PMC4887756, DOI: 10.1056/nejmoa1506930.
- Pioglitazone after Ischemic Stroke or Transient Ischemic AttackNew England Journal of Medicine 2016;374:1321-1331
- Kernan WN, Elnicki DM, Hauer KE. The Selling of Primary Care 2015. Journal Of General Internal Medicine 2015, 30: 1376-1380. PMID: 26173527, PMCID: PMC4539323, DOI: 10.1007/s11606-015-3364-9.
- Sico J, Viscoli C, Tayal A, Spence D, Ford G, Kernan W. Abstract W P369: International Variability in Stroke Preventive Care. Stroke 2015, 46 DOI: 10.1161/str.46.suppl_1.wp369.
- Kernan WN, Viscoli CM, Varughese MC. Litigation Seeking Access to Data From Ongoing Clinical Trials: A Threat to Clinical Research. JAMA Internal Medicine 2014, 174: 1502-1504. PMID: 25047222, PMCID: PMC5758866, DOI: 10.1001/jamainternmed.2014.3248.
- Kernan WN, Ovbiagele B, Black HR, Bravata DM, Chimowitz MI, Ezekowitz MD, Fang MC, Fisher M, Furie KL, Heck DV, Johnston SC, Kasner SE, Kittner SJ, Mitchell PH, Rich MW, Richardson D, Schwamm LH, Wilson JA. Guidelines for the Prevention of Stroke in Patients With Stroke and Transient Ischemic Attack. Stroke 2014, 45: 2160-2236. PMID: 24788967, DOI: 10.1161/str.0000000000000024.
- Preserving Research Integrity for Participants and the Public: Successful Defense against a Subpoena to Unblind an On-Going NIH TrialJAMA Intern Med 2014;174:1-3
- Zhang Z, Peluso MJ, Gross CP, Viscoli CM, Kernan WN. Adherence reporting in randomized controlled trials. Clinical Trials 2013, 11: 195-204. PMID: 24357665, DOI: 10.1177/1740774513512565.
- Kernan WN. Use of Recruitment Networks in Randomized Trials. Stroke 2013, 44: s119-s121. PMID: 23709705, DOI: 10.1161/strokeaha.111.000694.
- Kernan WN, Inzucchi SE, Sawan C, Macko RF, Furie KL. Obesity. Stroke 2012, 44: 278-286. PMID: 23111440, DOI: 10.1161/strokeaha.111.639922.
- Kernan WN, Inzucchi SE. Metabolic Rehabilitation. Stroke 2011, 42: 3333-3335. PMID: 21998067, PMCID: PMC3226842, DOI: 10.1161/strokeaha.111.632489.
- Kernan W, Viscoli C, Brass L, Amatangelo M, Birch A, Clark W, Conwit R, Furie K, Gorman M, Pesapane B, Kleindorfer D, Lovejoy A, Osborne J, Silliman S, Zweifler R, Horwitz R. Boosting enrolment in clinical trials: validation of a regional network model. Clinical Trials 2011, 8: 645-653. PMID: 21824978, PMCID: PMC3852692, DOI: 10.1177/1740774511414925.
- Durning SJ, Elnicki DM, Cruess DF, Reddy S, Kernan WN, Harrell HE, Schwartz MD, Fagan MJ, Battistone M, Hauer KE. Almost Internists: Analysis of Students Who Considered Internal Medicine but Chose Other Fields. Academic Medicine 2011, 86: 194-200. PMID: 21169784, DOI: 10.1097/acm.0b013e3182045ee5.
- Kernan WN, Launer LJ, Goldstein LB. What Is the Future of Stroke Prevention? Stroke 2010, 41: s35-s38. PMID: 20876501, PMCID: PMC4795938, DOI: 10.1161/strokeaha.110.592022.
- Kernan WN, Viscoli CM, DeMarco D, Mendes B, Shrauger K, Schindler JL, McVeety JC, Sicklick A, Moalli D, Greco P, Bravata DM, Eisen S, Resor L, Sena K, Story D, Brass LM, Furie KL, Gutmann L, Hinnau E, Gorman M, Lovejoy AM, Inzucchi SE, Young LH, Horwitz RI. Boosting enrollment in neurology trials with Local Identification and Outreach Networks (LIONs). Neurology 2009, 72: 1345-1351. PMID: 19365056, PMCID: PMC2677492, DOI: 10.1212/wnl.0b013e3181a0fda3.
- Hauer KE, Durning SJ, Kernan WN, Fagan MJ, Mintz M, O’Sullivan P, Battistone M, DeFer T, Elnicki M, Harrell H, Reddy S, Boscardin CK, Schwartz MD. Factors Associated With Medical Students' Career Choices Regarding Internal Medicine. JAMA 2008, 300: 1154-1164. PMID: 18780844, DOI: 10.1001/jama.300.10.1154.
- Hauer KE, Fagan MJ, Kernan W, Mintz M, Durning SJ. Internal Medicine Clerkship Directors’ Perceptions About Student Interest in Internal Medicine Careers. Journal Of General Internal Medicine 2008, 23: 1101-1104. PMID: 18612752, PMCID: PMC2517945, DOI: 10.1007/s11606-008-0640-y.
- Kernan WN, Hershman W, Alper EJ, Lee MY, Viscoli CM, Perry JR, O'Connor PG. Disagreement Between Students and Preceptors Regarding the Value of Teaching Behaviors for Ambulatory Care Settings. Teaching And Learning In Medicine 2008, 20: 143-150. PMID: 18444201, DOI: 10.1080/10401330801991667.
- Kernan WN, Schindler JL. Rapid intervention for TIA: a new standard emerges. The Lancet Neurology 2007, 6: 940-941. PMID: 17928271, DOI: 10.1016/s1474-4422(07)70249-1.
- Kernan WN. Stroke after transient ischaemic attack: dealing in futures. The Lancet 2007, 369: 251-252. PMID: 17258647, DOI: 10.1016/s0140-6736(07)60121-4.
- Yaggi HK, Concato J, Kernan WN, Lichtman JH, Brass LM, Mohsenin V. Obstructive Sleep Apnea as a Risk Factor for Stroke and Death. New England Journal Of Medicine 2005, 353: 2034-2041. PMID: 16282178, DOI: 10.1056/nejmoa043104.
- Rosenbaum JR, Wells CK, Viscoli CM, Brass LM, Kernan WN, Horwitz RI. Altruism as a reason for participation in clinical trials was independently associated with adherence. Journal Of Clinical Epidemiology 2005, 58: 1109-1114. PMID: 16223653, DOI: 10.1016/j.jclinepi.2005.03.014.
- Feldmann E, Broderick JP, Kernan WN, Viscoli CM, Brass LM, Brott T, Morgenstern LB, Wilterdink JL, Horwitz RI. Major Risk Factors for Intracerebral Hemorrhage in the Young Are Modifiable. Stroke 2005, 36: 1881-1885. PMID: 16081867, DOI: 10.1161/01.str.0000177480.62341.6b.
- Bravata DM, Wells CK, Kernan WN, Concato J, Brass LM, Gulanski BI. Association between Impaired Insulin Sensitivity and Stroke. Neuroepidemiology 2005, 25: 69-74. PMID: 15947493, DOI: 10.1159/000086286.
- Bravata DM, Wells CK, Gulanski B, Kernan WN, Brass LM, Long J, Concato J. Racial Disparities in Stroke Risk Factors. Stroke 2005, 36: 1507-1511. PMID: 15961710, DOI: 10.1161/01.str.0000170991.63594.b6.
- Kernan WN, Quagliarello V, Green ML. Student faculty rounds: a peer-mediated learning activity for internal medicine clerkships. Medical Teacher 2005, 27: 140-144. PMID: 16019334, DOI: 10.1080/01421590500047047.
- Viscoli CM, Brass LM, Kernan WN, Sarrel PM, Suissa S, Horwitz RI. Estrogen therapy and risk of cognitive decline: Results from the Women's Estrogen for Stroke Trial (WEST). American Journal Of Obstetrics And Gynecology 2005, 192: 387-393. PMID: 15695976, DOI: 10.1016/j.ajog.2004.08.017.
- Kernan WN, Viscoli CM, Brass LM, Gill TM, Sarrel PM, Horwitz RI. Decline in Physical Performance Among Women With a Recent Transient Ischemic Attack or Ischemic Stroke. Stroke 2005, 36: 630-634. PMID: 15677573, DOI: 10.1161/01.str.0000155728.42847.de.
- Kernan WN, Viscoli CM, Inzucchi SE, Brass LM, Bravata DM, Shulman GI, McVeety JC. Prevalence of Abnormal Glucose Tolerance Following a Transient Ischemic Attack or Ischemic Stroke. JAMA Internal Medicine 2005, 165: 227-233. PMID: 15668371, DOI: 10.1001/archinte.165.2.227.
- Kernan WN, Inzucchi SE. Type 2 diabetes mellitus and insulin resistance: Stroke prevention and management. Current Treatment Options In Neurology 2004, 6: 443-450. PMID: 15461922, DOI: 10.1007/s11940-004-0002-y.
- Bravata DM, Wells CK, Concato J, Kernan WN, Brass LM, Gulanski BI. Two measures of insulin sensitivity provided similar information in a U.S. population. Journal Of Clinical Epidemiology 2004, 57: 1214-1217. PMID: 15567640, DOI: 10.1016/j.jclinepi.2004.05.001.
- Kernan WN, Fagan MJ, Elnicki D, Council C. The clerkship directors in internal medicine's agenda for advancing medical student education in internal medicine. The American Journal Of Medicine 2004, 117: 713-717. PMID: 15501217, DOI: 10.1016/j.amjmed.2004.08.008.
- Kernan WN, Holmboe E, O'Connor PG. Assessing the Teaching Behaviors of Ambulatory Care Preceptors. Academic Medicine 2004, 79: 1088-1094. PMID: 15504778, DOI: 10.1097/00001888-200411000-00017.
- Kernan W. Abstracts From the Proceedings of the 2003 CDIM (Clerkship Directors of Internal Medicine) Annual Meeting. Teaching And Learning In Medicine 2004, 16: 296-300. DOI: 10.1207/s15328015tlm1603_14.
- Kernan WN. Re: Evaluation of acute candesartan cilexetil therapy in stroke survivors. Stroke 2003, 34: e237-8; author reply e237-8. PMID: 14631078, DOI: 10.1161/01.str.0000104158.59498.bc.
- Kernan W, Brass L, Viscoli C, Broderick J, Brott T, Feldmann E, Wilterdink J, Morgenstern L. Use of Ephedra-containing products and risk for hemorrhagic stroke. Neurology 2003, 61: 725. PMID: 12963785, DOI: 10.1212/wnl.61.5.724.
- Green ML, Gross CP, Kernan WN, Wong JG, Holmboe ES. Integrating Teaching Skills and Clinical Content in a Faculty Development Workshop. Journal Of General Internal Medicine 2003, 18: 468-474. PMID: 12823654, PMCID: PMC1494873, DOI: 10.1046/j.1525-1497.2003.20933.x.
- Broderick JP, Viscoli CM, Brott T, Kernan WN, Brass LM, Feldmann E, Morgenstern LB, Wilterdink JL, Horwitz RI. Major Risk Factors for Aneurysmal Subarachnoid Hemorrhage in the Young Are Modifiable. Stroke 2003, 34: 1375-1381. PMID: 12764233, DOI: 10.1161/01.str.0000074572.91827.f4.
- Kernan WN, Inzucchi SE, Viscoli CM, Brass LM, Bravata DM, Shulman GI, McVeety JC, Horwitz RI. Impaired insulin sensitivity among nondiabetic patients with a recent TIA or ischemic stroke. Neurology 2003, 60: 1447-1451. PMID: 12743229, DOI: 10.1212/01.wnl.0000063318.66140.a3.
- Kernan WN, Inzucchi SE, Viscoli CM, Brass LM, Bravata DM, Shulman GI, McVeety JC, Horwitz RI. Pioglitazone Improves Insulin Sensitivity Among Nondiabetic Patients With a Recent Transient Ischemic Attack or Ischemic Stroke. Stroke 2003, 34: 1431-1436. PMID: 12730556, DOI: 10.1161/01.str.0000071108.00234.0e.
- Corbie-Smith G, Viscoli CM, Kernan WN, Brass LM, Sarrel P, Horwitz RI. Influence of race, clinical, and other socio-demographic features on trial participation. Journal Of Clinical Epidemiology 2003, 56: 304-309. PMID: 12767406, DOI: 10.1016/s0895-4356(03)00046-5.
- Morgenstern LB, Viscoli CM, Kernan WN, Brass LM, Broderick JP, Feldmann E, Wilterdink JL, Brott T, Horwitz RI. Use of Ephedra-containing products and risk for hemorrhagic stroke. Neurology 2003, 60: 132-135. PMID: 12525737, DOI: 10.1212/01.wnl.0000042092.20411.5b.
- Kernan WN, Inzucchi SE, Viscoli CM, Brass LM, Bravata DM, Horwitz RI. Insulin resistance and risk for stroke. Neurology 2002, 59: 809-815. PMID: 12349850, DOI: 10.1212/wnl.59.6.809.
- Owens PL, Bradley EH, Horwitz SM, Viscoli CM, Kernan WN, Brass LM, Sarrel PM, Horwitz RI. Clinical assessment of function among women with a recent cerebrovascular event: a self-reported versus performance-based measure. Annals Of Internal Medicine 2002, 136: 802-11. PMID: 12044128, DOI: 10.7326/0003-4819-136-11-200206040-00008.
- Viscoli C, Brass L, Kernan W, Sarrel P, Suissa S, Horwitz R. A Clinical Trial of Estrogen-Replacement Therapy After Ischemic Stroke. Obstetrical & Gynecological Survey 2002, 57: 164-165. DOI: 10.1097/00006254-200203000-00019.
- Viscoli C, Brass L, Kernan W, Sarrel P, Suissa S, Horwitz R. A Clinical Trial of Estrogen-Replacement Therapy after Ischemic Stroke. New England Journal Of Medicine 2001, 345: 1243-1249. PMID: 11680444, DOI: 10.1056/nejmoa010534.
- Hamedani A, Wells C, Brass L, Kernan W, Viscoli C, Maraire J, Awad I, Horwitz R. A Quality-of-Life Instrument for Young Hemorrhagic Stroke Patients. Stroke 2001, 32: 687-695. PMID: 11239188, DOI: 10.1161/01.str.32.3.687.
- Kernan W, Makuch R. Response. Journal Of Clinical Epidemiology 2001, 54: 105. DOI: 10.1016/s0895-4356(00)00285-7.
- Kernan W, Viscoli C, Brass L, Broderick J, Brott T, Feldmann E, Morgenstern L, Wilterdink J, Horwitz R. Phenylpropanolamine and the Risk of Hemorrhagic Stroke. New England Journal Of Medicine 2000, 343: 1826-1832. PMID: 11117973, DOI: 10.1056/nejm200012213432501.
- Kernan W, Lee M, Stone S, Freudigman K, O’Connor P. Effective teaching for preceptors of ambulatory care: a survey of medical students. The American Journal Of Medicine 2000, 108: 499-502. PMID: 10781784, DOI: 10.1016/s0002-9343(00)00301-6.
- Kernan W, Viscoli C, Brass L, Makuch R, Sarrel P, Horwitz R. Blood Pressure Exceeding National Guidelines Among Women After Stroke. Stroke 2000, 31: 415-419. PMID: 10657415, DOI: 10.1161/01.str.31.2.415.
- Kernan W, Viscoli C, Brass L, Makuch R, Sarrel P, Roberts R, Gent M, Rothwell P, Sacco R, Liu R, Boden-Albala B, Horwitz R. The Stroke Prognosis Instrument II (SPI-II). Stroke 2000, 31: 456-462. PMID: 10657422, DOI: 10.1161/01.str.31.2.456.
- Kernan W, Viscoli C, Makuch R, Brass L, Horwitz R. Stratified Randomization for Clinical Trials. Journal Of Clinical Epidemiology 1999, 52: 19-26. PMID: 9973070, DOI: 10.1016/s0895-4356(98)00138-3.
- Kernan W, Brass L, Viscoli C, Sarrel P, Makuch R, Horwitz R. Estrogen after ischemic stroke: Clinical basis and design of The Women's Estrogen for Stroke Trial. Journal Of Stroke And Cerebrovascular Diseases 1998, 7: 85-95. PMID: 17895061, DOI: 10.1016/s1052-3057(98)80026-8.
- Kernan W, O'Connor P. Site accommodations and preceptor behaviors valued by 3rd‐year students in ambulatory internal medicine clerkships. Teaching And Learning In Medicine 1997, 9: 96-102. DOI: 10.1080/10401339709539822.
- Kernan W, Goroll A. A strategy for precepting medical students in ambulatory settings. Connecticut Medicine 1996, 60: 203-9. PMID: 8776123.
- Kernan W, Castellsague J, Perlman G, Ostfeld A. Incidence of hospitalization for digitalis toxicity among elderly Americans. The American Journal Of Medicine 1994, 96: 426-431. PMID: 8192174, DOI: 10.1016/0002-9343(94)90169-4.
- Kernan W, Horwitz R, Brass L, Viscoli C. Gender difference in prognosis after transient cerebral ischemia or minor stroke. Journal Of Stroke And Cerebrovascular Diseases 1994, 4: 148-154. PMID: 26486051, DOI: 10.1016/s1052-3057(10)80177-6.
- Kernan W, Feinstein A, Brass L. A methodological appraisal of research on prognosis after transient ischemic attacks. Stroke 1991, 22: 1108-1116. PMID: 1926253, DOI: 10.1161/01.str.22.9.1108.
- Kernan WN, Horwitz RI, Brass LM, Viscoli CM, Taylor KJ. A prognostic system for transient ischemia or minor stroke. Annals Of Internal Medicine 1991, 114: 552-7. PMID: 2001088, DOI: 10.7326/0003-4819-114-7-552.
- Burnand B, Kernan W, Feinstein A. Indexes and boundaries for “quantitative significance” in statistical decisions. Journal Of Clinical Epidemiology 1990, 43: 1273-1284. PMID: 2254764, DOI: 10.1016/0895-4356(90)90093-5.
- Brass L, Kernan W. Canadian Neurological Scale. Neurology 1989, 39: 1556-8. PMID: 2812344, DOI: 10.1212/wnl.39.11.1556.