Stephen Thung
Biography
Stephen Thung, MD, is a maternal-fetal medicine specialist and chair of Obstetrics, Gynecology, and Reproductive Sciences at Yale New Haven Health’s Bridgeport Hospital.
Growing up, Dr. Thung says he never imagined wanting to become a doctor. “I didn’t want to be in school forever. I wanted to start working and doing things right away,” he says. However, he was always drawn to sciences and by the end of college, realized that he was too much of a people person to be working with cell and tissue cultures in a laboratory.
“Still, I didn’t know what kind of doctor I wanted to be until I did my final rotation in medical school in obstetrics. There is nothing better than being on call when you are helping deliver babies and taking care of families as they go through a momentous time in their lives,” he says. “Everyone remembers their first baby, and it’s amazing to be a participant in that.”
As a maternal-fetal medicine specialist, Dr. Thung says his job is to help mothers with challenging conditions, such as diabetes, lupus, and hypertension in pregnancy and to make their pregnancies as healthy as possible.
“When I meet a patient for the first time, I let them know that I see difficult situations every day and, in most cases, what can be scary to most clinicians can be made into something a little more routine with the right team. We have the tools, experience, and resources to help them,” he says.
Dr. Thung’s particular area of expertise is endocrinological disorders in pregnancy with a specific interest in type 1 diabetes. “Treatment for type 1 diabetes has changed dramatically over the last few years with improving insulin pumps and sensor technology. But not all of this technology is aimed specifically for pregnant women, which can make care challenging,” he says. “I enjoy working with the patients and their families to figure out how we can use evidence-based medicine, and the latest technologies available to get the best euglycemic control and healthy mothers and babies.”
The best part of his job, Dr. Thung says, is working with patients. “I love developing relationships with people from all walks of life. When I am taking care of a patient, it blocks everything else out. My staff knows not to call or email or try to schedule a meeting with me on a patient day because I won’t respond,” he says.
Dr. Thung’s research interests include diabetes in pregnancy and cost utility models in medical practice. He is also vice chair of the Department of Obstetrics, Gynecology & Reproductive Sciences at Yale School of Medicine and an oral board examiner for the American Board of Obstetrics and Gynecology in both Obstetrics and Gynecology and Maternal Fetal Medicine.
Titles
- Professor of Obstetrics, Gynecology and Reproductive Sciences
- Vice Chair, Obstetrics, Gynecology & Reproductive Sciences
Education & Training
- FellowNorthwestern University Medical School, Chicago (2005)
- ResidentNew York University/Bellevue Hospital (2002)
Additional Information
- Field C, Lynch CD, Fareed N, Joseph JJ, Wu J, Thung SF, Gabbe SG, Landon MB, Grobman WA, Venkatesh KK. Association of community walkability and glycemic control among pregnant individuals with pregestational diabetes mellitus. Am J Obstet Gynecol MFM 2023, 5: 100898. PMID: 36787839, DOI: 10.1016/j.ajogmf.2023.100898.
- Li SS, Buschur E, Thung SF, Patel AV, Kirkby S. A multidisciplinary model for prenatal care for patients with cystic fibrosis in the era of highly effective modulator therapy. J Cyst Fibros 2023 PMID: 37019745, DOI: 10.1016/j.jcf.2023.03.014.
- Abdelwahab M, Frey HA, Lynch CD, Klebanoff MA, Thung SF, Costantine MM, Landon MB, Venkatesh KK. Association between Diabetes in Pregnancy and Shoulder Dystocia by Infant Birth Weight in an Era of Cesarean Delivery for Suspected Macrosomia. Am J Perinatol 2023 PMID: 36848935, DOI: 10.1055/s-0043-1764206.
- D'Amico R, Dalmacy D, Akinduro JA, Hyer M, Thung S, Mao S, Fareed N, Bose-Brill S. Patterns of Postpartum Primary Care Follow-up and Diabetes-Related Care After Diagnosis of Gestational Diabetes. JAMA Netw Open 2023, 6: e2254765. PMID: 36745454, DOI: 10.1001/jamanetworkopen.2022.54765.
- Venkatesh KK, Joseph JJ, Clark A, Gabbe SG, Landon MB, Thung SF, Yee LM, Lynch CD, Grobman WA, Walker DM. Association of community-level food insecurity and glycemic control among pregnant individuals with pregestational diabetes. Prim Care Diabetes 2023, 17: 73-78. PMID: 36379871, DOI: 10.1016/j.pcd.2022.11.002.
- Bose Brill S, May S, Lorenz AM, Spence D, Prater L, Shellhaas C, Otsubo M, Mao S, Flanigan M, Thung S, Leonard M, Jiang F, Oza-Frank R. Mother-Infant Dyad program in primary care: evidence-based postpartum care following gestational diabetes. J Matern Fetal Neonatal Med 2022, 35: 9336-9341. PMID: 35098857, DOI: 10.1080/14767058.2022.2032633.
- Venkatesh KK, Fareed N, Kiefer MK, Ware CA, Buschur E, Landon MB, Thung SF, Costantine MM, Gabbe SG, Joseph JJ. Differences in Hemoglobin A1c during Pregnancy between Non-Hispanic Black versus White Women with Prepregnancy Diabetes. Am J Perinatol 2022, 39: 1279-1287. PMID: 35253121, DOI: 10.1055/a-1788-5600.
- Brown JA, Leonard M, Clinton T, Bower JK, Gillespie SL, Fareed N, Thomas N, Prater L, Lorenz A, May S, Voisin C, Thung S, Oza-Frank R, Bose Brill S. Mothers' Perspectives on a Mother/Infant Dyad Postpartum Primary Care Program Following Gestational Diabetes Mellitus: A Qualitative Pilot Study. Sci Diabetes Self Manag Care 2022, 48: 247-257. PMID: 35658777, DOI: 10.1177/26350106221100539.
- Kiefer MK, Finneran MM, Ware CA, Fareed N, Joseph J, Thung SF, Costantine MM, Landon MB, Gabbe SG, Venkatesh KK. Association of change in haemoglobin A1c with adverse perinatal outcomes in women with pregestational diabetes. Diabet Med 2022, 39: e14822. PMID: 35261060, DOI: 10.1111/dme.14822.
- Venkatesh KK, Germann K, Joseph J, Kiefer M, Buschur E, Thung S, Costantine MM, Gabbe S, Grobman WA, Fareed N. Association Between Social Vulnerability and Achieving Glycemic Control Among Pregnant Individuals With Pregestational Diabetes. Obstet Gynecol 2022, 139: 1051-1060. PMID: 35675602, DOI: 10.1097/AOG.0000000000004727.
- Venkatesh KK, Lynch CD, Powe CE, Costantine MM, Thung SF, Gabbe SG, Grobman WA, Landon MB. Risk of Adverse Pregnancy Outcomes Among Pregnant Individuals With Gestational Diabetes by Race and Ethnicity in the United States, 2014-2020. JAMA 2022, 327: 1356-1367. PMID: 35412565, DOI: 10.1001/jama.2022.3189.
- Abdelwahab M, Lynch CD, Schneider P, Thung S, Costantine MM, O'Malley D, Landon MB, Pawlik TM, Venkatesh KK. Postoperative complications after non-obstetric surgery among pregnant patients in the National Surgical Quality Improvement Program, 2005-2012. Am J Surg 2022, 223: 364-369. PMID: 33865564, DOI: 10.1016/j.amjsurg.2021.04.002.
- Feingold KR, Anawalt B, Blackman MR, Boyce A, Chrousos G, Corpas E, de Herder WW, Dhatariya K, Dungan K, Hofland J, Kalra S, Kaltsas G, Kapoor N, Koch C, Kopp P, Korbonits M, Kovacs CS, Kuohung W, Laferrère B, Levy M, McGee EA, McLachlan R, New M, Purnell J, Sahay R, Shah AS, Singer F, Sperling MA, Stratakis CA, Trence DL, Wilson DP, Cleary EM, Thung SF, Buschur EO. Pregestational Diabetes Mellitus. 2021 PMID: 34370429.
- Feingold KR, Anawalt B, Blackman MR, Boyce A, Chrousos G, Corpas E, de Herder WW, Dhatariya K, Dungan K, Hofland J, Kalra S, Kaltsas G, Kapoor N, Koch C, Kopp P, Korbonits M, Kovacs CS, Kuohung W, Laferrère B, Levy M, McGee EA, McLachlan R, New M, Purnell J, Sahay R, Shah AS, Singer F, Sperling MA, Stratakis CA, Trence DL, Wilson DP, Cleary EM, Thung SF, Buschur EO. Gestational Diabetes. 2021 PMID: 34370430.
- Gee SE, Ma'ayeh M, Cackovic H, Samuels P, Thung SF, Landon MB, Rood KM. Addition of vaginal isosorbide mononitrate for labor induction in pregnancies complicated by hypertensive diseases of pregnancy: a randomized controlled trial. Am J Obstet Gynecol MFM 2021, 3: 100343. PMID: 33652160, DOI: 10.1016/j.ajogmf.2021.100343.
- Stith BJ, Buls SM, Keim SA, Thung SF, Klebanoff MA, Landon MB, Gabbe SG, Gandhi KK, Oza-Frank R. Moms in motion: weight loss intervention for postpartum mothers after gestational diabetes: a randomized controlled trial. BMC Pregnancy Childbirth 2021, 21: 461. PMID: 34187391, DOI: 10.1186/s12884-021-03886-3.
- Boyles GP, Thung S, Gabbe SG, Landon MB, Costantine MM. Practical considerations for pregnant women with diabetes and severe acute respiratory syndrome coronavirus 2 infection. Am J Obstet Gynecol MFM 2020, 2: 100210. PMID: 32838276, DOI: 10.1016/j.ajogmf.2020.100210.
- Williams JEP, Bazan JA, Turner AN, Thung SF, Hanlon C, Pettus TR, Sánchez PJ. Reverse Sequence Syphilis Screening and Discordant Results in Pregnancy. J Pediatr 2020, 219: 263-266.e1. PMID: 32093931, DOI: 10.1016/j.jpeds.2019.11.035.
- Finneran MM, Kiefer MK, Ware CA, Buschur EO, Thung SF, Landon MB, Gabbe SG. The use of longitudinal hemoglobin A1c values to predict adverse obstetric and neonatal outcomes in pregnancies complicated by pregestational diabetes. Am J Obstet Gynecol MFM 2020, 2: 100069. PMID: 33345983, DOI: 10.1016/j.ajogmf.2019.100069.
- Finneran MM, Ware CA, Kiefer MK, Buschur EO, Foy PM, Thung SF, Landon MB, Gabbe SG. The Accuracy and Cost-Effectiveness of Selective Fetal Echocardiography for the Diagnosis of Congenital Heart Disease in Patients with Pregestational Diabetes Stratified by Hemoglobin A1c. Am J Perinatol 2019, 36: 1216-1222. PMID: 30991442, DOI: 10.1055/s-0039-1685490.
- Rood KM, Buhimschi IA, Jurcisek JA, Summerfield TL, Zhao G, Ackerman WE, Wang W, Rumpf RW, Thung SF, Bakaletz LO, Buhimschi CS. Skin Microbiota in Obese Women at Risk for Surgical Site Infection After Cesarean Delivery. Scientific Reports 2018, 8: 8756. PMID: 29884793, PMCID: PMC5993816, DOI: 10.1038/s41598-018-27134-5.
- Caughey AB, Zupancic JA, Greenberg JM, Garfield SS, Thung SF, Iams JD. Clinical and Cost Impact Analysis of a Novel Prognostic Test for Early Detection of Preterm Birth. AJP Rep 2016, 6: e407-e416. PMID: 27917307, DOI: 10.1055/s-0036-1593866.
- Rood KM, Buhimschi IA, Rodewald Millen K, Bahtiyar MO, Thung S, Summerfield T, Zhao G, Ackerman W, Shellhaas C, Samuels P, Buhimschi CS. Evidence for participation of neutrophil gelatinase‐associated lipocalin/matrix metalloproteinase‐9 (NGAL•MMP‐9) complex in the inflammatory response to infection in pregnancies complicated by preterm birth. American Journal Of Reproductive Immunology 2016, 76: 108-117. PMID: 27251223, PMCID: PMC4942349, DOI: 10.1111/aji.12523.
- Baumbusch MA, Buhimschi CS, Oliver EA, Zhao G, Thung S, Rood K, Buhimschi IA. High Mobility Group-Box 1 (HMGB1) levels are increased in amniotic fluid of women with intra-amniotic inflammation-determined preterm birth, and the source may be the damaged fetal membranes. Cytokine 2016, 81: 82-7. PMID: 26954343, PMCID: PMC4803598, DOI: 10.1016/j.cyto.2016.02.013.
- Werner EF, Hamel MS, Orzechowski K, Berghella V, Thung SF. Cost-effectiveness of transvaginal ultrasound cervical length screening in singletons without a prior preterm birth: an update. Am J Obstet Gynecol 2015, 213: 554.e1-6. PMID: 26071914, DOI: 10.1016/j.ajog.2015.06.020.
- Dulay AT, Buhimschi IA, Zhao G, Bahtiyar MO, Thung SF, Cackovic M, Buhimschi CS. Compartmentalization of acute phase reactants Interleukin-6, C-Reactive Protein and Procalcitonin as biomarkers of intra-amniotic infection and chorioamnionitis. Cytokine 2015, 76: 236-243. PMID: 25957466, PMCID: PMC4824401, DOI: 10.1016/j.cyto.2015.04.014.
- Kunkle CM, Hallock JL, Hu X, Blomquist J, Thung SF, Werner EF. Cost utility analysis of urethral bulking agents versus midurethral sling in stress urinary incontinence. Female Pelvic Med Reconstr Surg 2015, 21: 154-9. PMID: 25730435, DOI: 10.1097/SPV.0000000000000173.
- Washington CI, Jamshidi R, Thung SF, Nayeri UA, Caughey AB, Werner EF. Timing of postpartum intrauterine device placement: a cost-effectiveness analysis. Fertil Steril 2015, 103: 131-7. PMID: 25439838, DOI: 10.1016/j.fertnstert.2014.09.032.
- Pettker CM, Thung SF, Lipkind HS, Illuzzi JL, Buhimschi CS, Raab CA, Copel JA, Lockwood CJ, Funai EF. A comprehensive obstetric patient safety program reduces liability claims and payments. American Journal Of Obstetrics And Gynecology 2014, 211: 319-325. PMID: 24925798, DOI: 10.1016/j.ajog.2014.04.038.
- Schuster KM, Jenq GY, Thung SF, Hersh DC, Nunes J, Silverman DG, Horwitz LI. Electronic handoff instruments: a truly multidisciplinary tool? Journal Of The American Medical Informatics Association 2014, 21: e352-e357. PMID: 24553477, PMCID: PMC4173175, DOI: 10.1136/amiajnl-2013-002361.
- Cordero L, Thung S, Landon MB, Nankervis CA. Breast-feeding initiation in women with pregestational diabetes mellitus. Clin Pediatr (Phila) 2014, 53: 18-25. PMID: 23884968, DOI: 10.1177/0009922813496455.
- Thung SF, Landon MB. Fetal surveillance and timing of delivery in pregnancy complicated by diabetes mellitus. Clin Obstet Gynecol 2013, 56: 837-43. PMID: 24071732, DOI: 10.1097/GRF.0b013e3182a9e504.
- Werner EF, Savitz DA, Janevic TM, Ehsanipoor RM, Thung SF, Funai EF, Lipkind HS. Mode of Delivery and Neonatal Outcomes in Preterm, Small-for-Gestational-Age Newborns. Obstetrics And Gynecology 2012, 120: 560-564. PMID: 22914464, PMCID: PMC3739844, DOI: 10.1097/aog.0b013e318265b16c.
- Zuckerwise LC, Werner EF, Pettker CM, McMahon-Brown EK, Thung SF, Han CS. Pregestational Diabetes With Extreme Insulin Resistance. Obstetrics And Gynecology 2012, 120: 439-442. PMID: 22825259, DOI: 10.1097/aog.0b013e31824fd27d.
- Werner E, Han C, Burd I, Lipkind H, Copel J, Bahtiyar M, Thung S. Evaluating the cost‐effectiveness of prenatal surgery for myelomeningocele: a decision analysis. Ultrasound In Obstetrics And Gynecology 2012, 40: 158-164. PMID: 22511529, DOI: 10.1002/uog.11176.
- Nayeri UA, Werner EF, Han CS, Pettker CM, Funai EF, Thung SF. Antenatal lamivudine to reduce perinatal hepatitis B transmission: a cost-effectiveness analysis. American Journal Of Obstetrics And Gynecology 2012, 207: 231.e1-231.e7. PMID: 22939730, DOI: 10.1016/j.ajog.2012.06.001.
- Horwitz LI, Schuster KM, Thung SF, Hersh DC, Fisher RL, Shah N, Cushing W, Nunes J, Silverman DG, Jenq GY. An institution-wide handoff task force to standardise and improve physician handoffs. BMJ Quality & Safety 2012, 21: 863. PMID: 22626740, PMCID: PMC3463404, DOI: 10.1136/bmjqs-2011-000658.
- Werner EF, Pettker CM, Zuckerwise L, Reel M, Funai EF, Henderson J, Thung SF. Screening for Gestational Diabetes Mellitus: Are the Criteria Proposed by the International Association of the Diabetes and Pregnancy Study Groups Cost-Effective? Diabetes Care 2012, 35: 529-535. PMID: 22266735, PMCID: PMC3322683, DOI: 10.2337/dc11-1643.
- Chen HW, Bercik RS, Werner EF, Thung SF. Cost-Effectiveness of Percutaneous Tibial Nerve Stimulation Versus Extended Release Tolterodine for Overactive Bladder. Journal Of Urology 2011, 187: 178-184. PMID: 22100006, DOI: 10.1016/j.juro.2011.09.052.
- Buhimschi CS, Bhandari V, Dulay AT, Nayeri UA, Abdel-Razeq SS, Pettker CM, Thung S, Zhao G, Han YW, Bizzarro M, Buhimschi IA. Proteomics Mapping of Cord Blood Identifies Haptoglobin “Switch-On” Pattern as Biomarker of Early-Onset Neonatal Sepsis in Preterm Newborns. PLOS ONE 2011, 6: e26111. PMID: 22028810, PMCID: PMC3189953, DOI: 10.1371/journal.pone.0026111.
- Buhimschi CS, Buhimschi IA, Wehrum MJ, Molaskey-Jones S, Sfakianaki AK, Pettker CM, Thung S, Campbell KH, Dulay AT, Funai EF, Bahtiyar MO. Ultrasonographic Evaluation of Myometrial Thickness and Prediction of a Successful External Cephalic Version. Obstetrics And Gynecology 2011, 118: 913-920. PMID: 21934456, DOI: 10.1097/aog.0b013e31822e63fe.
- Werner EF, Han CS, Pettker CM, Buhimschi CS, Copel JA, Funai EF, Thung SF. Universal cervical‐length screening to prevent preterm birth: a cost‐effectiveness analysis. Ultrasound In Obstetrics And Gynecology 2011, 38: 32-37. PMID: 21157771, DOI: 10.1002/uog.8911.
- Lee SY, Buhimschi IA, Dulay AT, Ali UA, Zhao G, Abdel-Razeq SS, Bahtiyar MO, Thung SF, Funai EF, Buhimschi CS. IL-6 Trans-Signaling System in Intra-Amniotic Inflammation, Preterm Birth, and Preterm Premature Rupture of the Membranes. The Journal Of Immunology 2011, 186: 3226-3236. PMID: 21282511, PMCID: PMC3800180, DOI: 10.4049/jimmunol.1003587.
- Pettker CM, Thung SF, Raab CA, Donohue KP, Copel JA, Lockwood CJ, Funai EF. A comprehensive obstetrics patient safety program improves safety climate and culture. American Journal Of Obstetrics And Gynecology 2011, 204: 216.e1-216.e6. PMID: 21376160, DOI: 10.1016/j.ajog.2010.11.004.
- Wehrum MJ, Buhimschi IA, Salafia C, Thung S, Bahtiyar MO, Werner EF, Campbell KH, Laky C, Sfakianaki AK, Zhao G, Funai EF, Buhimschi CS. Accreta complicating complete placenta previa is characterized by reduced systemic levels of vascular endothelial growth factor and by epithelial-to-mesenchymal transition of the invasive trophoblast. American Journal Of Obstetrics And Gynecology 2011, 204: 411.e1-411.e11. PMID: 21316642, PMCID: PMC3136625, DOI: 10.1016/j.ajog.2010.12.027.
- Abdel-Razeq SS, Buhimschi IA, Bahtiyar MO, Rosenberg VA, Dulay AT, Han CS, Werner EF, Thung S, Buhimschi CS. Interpretation of Amniotic Fluid White Blood Cell Count in “Bloody Tap” Amniocenteses in Women With Symptoms of Preterm Labor. Obstetrics And Gynecology 2010, 116: 344-354. PMID: 20664395, PMCID: PMC4142228, DOI: 10.1097/aog.0b013e3181e8fec6.
- Buhimschi CS, Bhandari V, Dulay AT, Thung S, Razeq SS, Rosenberg V, Han CS, Ali UA, Zambrano E, Zhao G, Funai EF, Buhimschi IA. Amniotic fluid angiopoietin-1, angiopoietin-2, and soluble receptor tunica interna endothelial cell kinase-2 levels and regulation in normal pregnancy and intraamniotic inflammation-induced preterm birth. The Journal Of Clinical Endocrinology And Metabolism 2010, 95: 3428-36. PMID: 20410222, PMCID: PMC2928907, DOI: 10.1210/jc.2009-2829.
- Azpurua H, Norwitz ER, Campbell KH, Funai EF, Pettker CM, Kleine M, Bahtiyar MO, Malkus H, Copel JA, Thung SF. Acceleration/ejection time ratio in the fetal pulmonary artery predicts fetal lung maturity. American Journal Of Obstetrics And Gynecology 2010, 203: 40.e1-40.e8. PMID: 20417479, DOI: 10.1016/j.ajog.2010.01.075.
- Bulun SE, Cheng YH, Pavone ME, Xue Q, Attar E, Trukhacheva E, Tokunaga H, Utsunomiya H, Yin P, Luo X, Lin Z, Imir G, Thung S, Su EJ, Kim JJ. Estrogen receptor-beta, estrogen receptor-alpha, and progesterone resistance in endometriosis. Semin Reprod Med 2010, 28: 36-43. PMID: 20104427, DOI: 10.1055/s-0029-1242991.
- Bulun SE, Cheng YH, Pavone ME, Yin P, Imir G, Utsunomiya H, Thung S, Xue Q, Marsh EE, Tokunaga H, Ishikawa H, Kurita T, Su EJ. 17Beta-hydroxysteroid dehydrogenase-2 deficiency and progesterone resistance in endometriosis. Semin Reprod Med 2010, 28: 44-50. PMID: 20108182, DOI: 10.1055/s-0029-1242992.
- Thung SF, Norwitz ER. Postpartum care: we can and should do better. Am J Obstet Gynecol 2010, 202: 1-4. PMID: 20096251, DOI: 10.1016/j.ajog.2009.08.028.
- Pettker CM, Thung SF, Dulay A, Han C, Ali U. Discussion: ‘Predicting neonatal acidemia by computer analysis’ by Costa et al. American Journal Of Obstetrics And Gynecology 2009, 201: e1-e4. PMID: 19879389, DOI: 10.1016/j.ajog.2009.08.014.
- Richter CE, Saber S, Thung SF. Eclampsia complicated by abdominal compartment syndrome. Am J Perinatol 2009, 26: 751-3. PMID: 19444766, DOI: 10.1055/s-0029-1223289.
- Carlson A, Thung SF, Norwitz ER. H1N1 Influenza in Pregnancy: What All Obstetric Care Providers Ought to Know. Rev Obstet Gynecol 2009, 2: 139-45. PMID: 19826571.
- Thung SF, Funai EF, Grobman WA. The cost-effectiveness of universal screening in pregnancy for subclinical hypothyroidism. American Journal Of Obstetrics And Gynecology 2009, 200: 267.e1-7. PMID: 19114278, DOI: 10.1016/j.ajog.2008.10.035.
- Pettker CM, Thung SF, Norwitz ER, Buhimschi CS, Raab CA, Copel JA, Kuczynski E, Lockwood CJ, Funai EF. Impact of a comprehensive patient safety strategy on obstetric adverse events. American Journal Of Obstetrics And Gynecology 2009, 200: 492.e1-492.e8. PMID: 19249729, DOI: 10.1016/j.ajog.2009.01.022.
- Buhimschi IA, Zhao G, Rosenberg VA, Abdel-Razeq S, Thung S, Buhimschi CS. Multidimensional Proteomics Analysis of Amniotic Fluid to Provide Insight into the Mechanisms of Idiopathic Preterm Birth. PLOS ONE 2008, 3: e2049. PMID: 18431506, PMCID: PMC2315798, DOI: 10.1371/journal.pone.0002049.
- Utsunomiya H, Cheng YH, Lin Z, Reierstad S, Yin P, Attar E, Xue Q, Imir G, Thung S, Trukhacheva E, Suzuki T, Sasano H, Kim JJ, Yaegashi N, Bulun SE. Upstream stimulatory factor-2 regulates steroidogenic factor-1 expression in endometriosis. Mol Endocrinol 2008, 22: 904-14. PMID: 18165439, DOI: 10.1210/me.2006-0302.
- Dulay AT, Buhimschi IA, Zhao G, Luo G, Abdel-Razeq S, Cackovic M, Rosenberg VA, Pettker CM, Thung SF, Bahtiyar MO, Bhandari V, Buhimschi CS. Nucleated red blood cells are a direct response to mediators of inflammation in newborns with early-onset neonatal sepsis. American Journal Of Obstetrics And Gynecology 2008, 198: 426.e1-426.e9. PMID: 18395034, PMCID: PMC4023236, DOI: 10.1016/j.ajog.2008.01.040.
- Buhimschi C, Rosenberg V, Dulay A, Thung S, Sfakianaki A, Bahtiyar M, Buhimschi I. Multidimensional System Biology: Genetic Markers and Proteomic Biomarkers of Adverse Pregnancy Outcome in Preterm Birth. American Journal Of Perinatology 2008, 25: 175-187. PMID: 18425720, DOI: 10.1055/s-2008-1061497.
- Buhimschi IA, Zambrano E, Pettker CM, Bahtiyar MO, Paidas M, Rosenberg VA, Thung S, Salafia CM, Buhimschi CS. Using Proteomic Analysis of the Human Amniotic Fluid to Identify Histologic Chorioamnionitis. Obstetrics And Gynecology 2008, 111: 403-412. PMID: 18238979, DOI: 10.1097/aog.0b013e31816102aa.
- Yin P, Lin Z, Cheng YH, Marsh EE, Utsunomiya H, Ishikawa H, Xue Q, Reierstad S, Innes J, Thung S, Kim JJ, Xu E, Bulun SE. Progesterone receptor regulates Bcl-2 gene expression through direct binding to its promoter region in uterine leiomyoma cells. J Clin Endocrinol Metab 2007, 92: 4459-66. PMID: 17785366, DOI: 10.1210/jc.2007-0725.
- Bulun SE, Chen D, Lu M, Zhao H, Cheng Y, Demura M, Yilmaz B, Martin R, Utsunomiya H, Thung S, Su E, Marsh E, Hakim A, Yin P, Ishikawa H, Amin S, Imir G, Gurates B, Attar E, Reierstad S, Innes J, Lin Z. Aromatase excess in cancers of breast, endometrium and ovary. J Steroid Biochem Mol Biol 2007, 106: 81-96. PMID: 17590327, DOI: 10.1016/j.jsbmb.2007.05.027.
- Buhimschi CS, Buhimschi IA, Abdel-Razeq S, Rosenberg VA, Thung SF, Zhao G, Wang E, Bhandari V. Proteomic Biomarkers of Intra-amniotic Inflammation: Relationship with Funisitis and Early-onset Sepsis in the Premature Neonate. Pediatric Research 2007, 61: 318-324. PMID: 17314690, DOI: 10.1203/01.pdr.0000252439.48564.37.
- Buhimschi IA, Zhao G, Pettker CM, Bahtiyar MO, Magloire LK, Thung S, Fairchild T, Buhimschi CS. The receptor for advanced glycation end products (RAGE) system in women with intraamniotic infection and inflammation. American Journal Of Obstetrics And Gynecology 2007, 196: 181.e1-181.e13. PMID: 17306673, DOI: 10.1016/j.ajog.2006.09.001.
- Thung SF, Grobman WA. The cost effectiveness of empiric intravenous immunoglobulin for the antepartum treatment of fetal and neonatal alloimmune thrombocytopenia. Am J Obstet Gynecol 2005, 193: 1094-9. PMID: 16157118, DOI: 10.1016/j.ajog.2005.05.048.
- Bulun SE, Lin Z, Imir G, Amin S, Demura M, Yilmaz B, Martin R, Utsunomiya H, Thung S, Gurates B, Tamura M, Langoi D, Deb S. Regulation of aromatase expression in estrogen-responsive breast and uterine disease: from bench to treatment. Pharmacol Rev 2005, 57: 359-83. PMID: 16109840, DOI: 10.1124/pr.57.3.6.
- Bulun SE, Imir G, Utsunomiya H, Thung S, Gurates B, Tamura M, Lin Z. Aromatase in endometriosis and uterine leiomyomata. J Steroid Biochem Mol Biol 2005, 95: 57-62. PMID: 16024248, DOI: 10.1016/j.jsbmb.2005.04.012.
- Thung SF, Grobman WA. The cost-effectiveness of routine antenatal screening for maternal herpes simplex virus-1 and -2 antibodies. Am J Obstet Gynecol 2005, 192: 483-8. PMID: 15695991, DOI: 10.1016/j.ajog.2004.09.134.
Biography
Stephen Thung, MD, is a maternal-fetal medicine specialist and chair of Obstetrics, Gynecology, and Reproductive Sciences at Yale New Haven Health’s Bridgeport Hospital.
Growing up, Dr. Thung says he never imagined wanting to become a doctor. “I didn’t want to be in school forever. I wanted to start working and doing things right away,” he says. However, he was always drawn to sciences and by the end of college, realized that he was too much of a people person to be working with cell and tissue cultures in a laboratory.
“Still, I didn’t know what kind of doctor I wanted to be until I did my final rotation in medical school in obstetrics. There is nothing better than being on call when you are helping deliver babies and taking care of families as they go through a momentous time in their lives,” he says. “Everyone remembers their first baby, and it’s amazing to be a participant in that.”
As a maternal-fetal medicine specialist, Dr. Thung says his job is to help mothers with challenging conditions, such as diabetes, lupus, and hypertension in pregnancy and to make their pregnancies as healthy as possible.
“When I meet a patient for the first time, I let them know that I see difficult situations every day and, in most cases, what can be scary to most clinicians can be made into something a little more routine with the right team. We have the tools, experience, and resources to help them,” he says.
Dr. Thung’s particular area of expertise is endocrinological disorders in pregnancy with a specific interest in type 1 diabetes. “Treatment for type 1 diabetes has changed dramatically over the last few years with improving insulin pumps and sensor technology. But not all of this technology is aimed specifically for pregnant women, which can make care challenging,” he says. “I enjoy working with the patients and their families to figure out how we can use evidence-based medicine, and the latest technologies available to get the best euglycemic control and healthy mothers and babies.”
The best part of his job, Dr. Thung says, is working with patients. “I love developing relationships with people from all walks of life. When I am taking care of a patient, it blocks everything else out. My staff knows not to call or email or try to schedule a meeting with me on a patient day because I won’t respond,” he says.
Dr. Thung’s research interests include diabetes in pregnancy and cost utility models in medical practice. He is also vice chair of the Department of Obstetrics, Gynecology & Reproductive Sciences at Yale School of Medicine and an oral board examiner for the American Board of Obstetrics and Gynecology in both Obstetrics and Gynecology and Maternal Fetal Medicine.
Titles
- Professor of Obstetrics, Gynecology and Reproductive Sciences
- Vice Chair, Obstetrics, Gynecology & Reproductive Sciences
Education & Training
- FellowNorthwestern University Medical School, Chicago (2005)
- ResidentNew York University/Bellevue Hospital (2002)
Additional Information
- Field C, Lynch CD, Fareed N, Joseph JJ, Wu J, Thung SF, Gabbe SG, Landon MB, Grobman WA, Venkatesh KK. Association of community walkability and glycemic control among pregnant individuals with pregestational diabetes mellitus. Am J Obstet Gynecol MFM 2023, 5: 100898. PMID: 36787839, DOI: 10.1016/j.ajogmf.2023.100898.
- Li SS, Buschur E, Thung SF, Patel AV, Kirkby S. A multidisciplinary model for prenatal care for patients with cystic fibrosis in the era of highly effective modulator therapy. J Cyst Fibros 2023 PMID: 37019745, DOI: 10.1016/j.jcf.2023.03.014.
- Abdelwahab M, Frey HA, Lynch CD, Klebanoff MA, Thung SF, Costantine MM, Landon MB, Venkatesh KK. Association between Diabetes in Pregnancy and Shoulder Dystocia by Infant Birth Weight in an Era of Cesarean Delivery for Suspected Macrosomia. Am J Perinatol 2023 PMID: 36848935, DOI: 10.1055/s-0043-1764206.
- D'Amico R, Dalmacy D, Akinduro JA, Hyer M, Thung S, Mao S, Fareed N, Bose-Brill S. Patterns of Postpartum Primary Care Follow-up and Diabetes-Related Care After Diagnosis of Gestational Diabetes. JAMA Netw Open 2023, 6: e2254765. PMID: 36745454, DOI: 10.1001/jamanetworkopen.2022.54765.
- Venkatesh KK, Joseph JJ, Clark A, Gabbe SG, Landon MB, Thung SF, Yee LM, Lynch CD, Grobman WA, Walker DM. Association of community-level food insecurity and glycemic control among pregnant individuals with pregestational diabetes. Prim Care Diabetes 2023, 17: 73-78. PMID: 36379871, DOI: 10.1016/j.pcd.2022.11.002.
- Bose Brill S, May S, Lorenz AM, Spence D, Prater L, Shellhaas C, Otsubo M, Mao S, Flanigan M, Thung S, Leonard M, Jiang F, Oza-Frank R. Mother-Infant Dyad program in primary care: evidence-based postpartum care following gestational diabetes. J Matern Fetal Neonatal Med 2022, 35: 9336-9341. PMID: 35098857, DOI: 10.1080/14767058.2022.2032633.
- Venkatesh KK, Fareed N, Kiefer MK, Ware CA, Buschur E, Landon MB, Thung SF, Costantine MM, Gabbe SG, Joseph JJ. Differences in Hemoglobin A1c during Pregnancy between Non-Hispanic Black versus White Women with Prepregnancy Diabetes. Am J Perinatol 2022, 39: 1279-1287. PMID: 35253121, DOI: 10.1055/a-1788-5600.
- Brown JA, Leonard M, Clinton T, Bower JK, Gillespie SL, Fareed N, Thomas N, Prater L, Lorenz A, May S, Voisin C, Thung S, Oza-Frank R, Bose Brill S. Mothers' Perspectives on a Mother/Infant Dyad Postpartum Primary Care Program Following Gestational Diabetes Mellitus: A Qualitative Pilot Study. Sci Diabetes Self Manag Care 2022, 48: 247-257. PMID: 35658777, DOI: 10.1177/26350106221100539.
- Kiefer MK, Finneran MM, Ware CA, Fareed N, Joseph J, Thung SF, Costantine MM, Landon MB, Gabbe SG, Venkatesh KK. Association of change in haemoglobin A1c with adverse perinatal outcomes in women with pregestational diabetes. Diabet Med 2022, 39: e14822. PMID: 35261060, DOI: 10.1111/dme.14822.
- Venkatesh KK, Germann K, Joseph J, Kiefer M, Buschur E, Thung S, Costantine MM, Gabbe S, Grobman WA, Fareed N. Association Between Social Vulnerability and Achieving Glycemic Control Among Pregnant Individuals With Pregestational Diabetes. Obstet Gynecol 2022, 139: 1051-1060. PMID: 35675602, DOI: 10.1097/AOG.0000000000004727.
- Venkatesh KK, Lynch CD, Powe CE, Costantine MM, Thung SF, Gabbe SG, Grobman WA, Landon MB. Risk of Adverse Pregnancy Outcomes Among Pregnant Individuals With Gestational Diabetes by Race and Ethnicity in the United States, 2014-2020. JAMA 2022, 327: 1356-1367. PMID: 35412565, DOI: 10.1001/jama.2022.3189.
- Abdelwahab M, Lynch CD, Schneider P, Thung S, Costantine MM, O'Malley D, Landon MB, Pawlik TM, Venkatesh KK. Postoperative complications after non-obstetric surgery among pregnant patients in the National Surgical Quality Improvement Program, 2005-2012. Am J Surg 2022, 223: 364-369. PMID: 33865564, DOI: 10.1016/j.amjsurg.2021.04.002.
- Feingold KR, Anawalt B, Blackman MR, Boyce A, Chrousos G, Corpas E, de Herder WW, Dhatariya K, Dungan K, Hofland J, Kalra S, Kaltsas G, Kapoor N, Koch C, Kopp P, Korbonits M, Kovacs CS, Kuohung W, Laferrère B, Levy M, McGee EA, McLachlan R, New M, Purnell J, Sahay R, Shah AS, Singer F, Sperling MA, Stratakis CA, Trence DL, Wilson DP, Cleary EM, Thung SF, Buschur EO. Pregestational Diabetes Mellitus. 2021 PMID: 34370429.
- Feingold KR, Anawalt B, Blackman MR, Boyce A, Chrousos G, Corpas E, de Herder WW, Dhatariya K, Dungan K, Hofland J, Kalra S, Kaltsas G, Kapoor N, Koch C, Kopp P, Korbonits M, Kovacs CS, Kuohung W, Laferrère B, Levy M, McGee EA, McLachlan R, New M, Purnell J, Sahay R, Shah AS, Singer F, Sperling MA, Stratakis CA, Trence DL, Wilson DP, Cleary EM, Thung SF, Buschur EO. Gestational Diabetes. 2021 PMID: 34370430.
- Gee SE, Ma'ayeh M, Cackovic H, Samuels P, Thung SF, Landon MB, Rood KM. Addition of vaginal isosorbide mononitrate for labor induction in pregnancies complicated by hypertensive diseases of pregnancy: a randomized controlled trial. Am J Obstet Gynecol MFM 2021, 3: 100343. PMID: 33652160, DOI: 10.1016/j.ajogmf.2021.100343.
- Stith BJ, Buls SM, Keim SA, Thung SF, Klebanoff MA, Landon MB, Gabbe SG, Gandhi KK, Oza-Frank R. Moms in motion: weight loss intervention for postpartum mothers after gestational diabetes: a randomized controlled trial. BMC Pregnancy Childbirth 2021, 21: 461. PMID: 34187391, DOI: 10.1186/s12884-021-03886-3.
- Boyles GP, Thung S, Gabbe SG, Landon MB, Costantine MM. Practical considerations for pregnant women with diabetes and severe acute respiratory syndrome coronavirus 2 infection. Am J Obstet Gynecol MFM 2020, 2: 100210. PMID: 32838276, DOI: 10.1016/j.ajogmf.2020.100210.
- Williams JEP, Bazan JA, Turner AN, Thung SF, Hanlon C, Pettus TR, Sánchez PJ. Reverse Sequence Syphilis Screening and Discordant Results in Pregnancy. J Pediatr 2020, 219: 263-266.e1. PMID: 32093931, DOI: 10.1016/j.jpeds.2019.11.035.
- Finneran MM, Kiefer MK, Ware CA, Buschur EO, Thung SF, Landon MB, Gabbe SG. The use of longitudinal hemoglobin A1c values to predict adverse obstetric and neonatal outcomes in pregnancies complicated by pregestational diabetes. Am J Obstet Gynecol MFM 2020, 2: 100069. PMID: 33345983, DOI: 10.1016/j.ajogmf.2019.100069.
- Finneran MM, Ware CA, Kiefer MK, Buschur EO, Foy PM, Thung SF, Landon MB, Gabbe SG. The Accuracy and Cost-Effectiveness of Selective Fetal Echocardiography for the Diagnosis of Congenital Heart Disease in Patients with Pregestational Diabetes Stratified by Hemoglobin A1c. Am J Perinatol 2019, 36: 1216-1222. PMID: 30991442, DOI: 10.1055/s-0039-1685490.
- Rood KM, Buhimschi IA, Jurcisek JA, Summerfield TL, Zhao G, Ackerman WE, Wang W, Rumpf RW, Thung SF, Bakaletz LO, Buhimschi CS. Skin Microbiota in Obese Women at Risk for Surgical Site Infection After Cesarean Delivery. Scientific Reports 2018, 8: 8756. PMID: 29884793, PMCID: PMC5993816, DOI: 10.1038/s41598-018-27134-5.
- Caughey AB, Zupancic JA, Greenberg JM, Garfield SS, Thung SF, Iams JD. Clinical and Cost Impact Analysis of a Novel Prognostic Test for Early Detection of Preterm Birth. AJP Rep 2016, 6: e407-e416. PMID: 27917307, DOI: 10.1055/s-0036-1593866.
- Rood KM, Buhimschi IA, Rodewald Millen K, Bahtiyar MO, Thung S, Summerfield T, Zhao G, Ackerman W, Shellhaas C, Samuels P, Buhimschi CS. Evidence for participation of neutrophil gelatinase‐associated lipocalin/matrix metalloproteinase‐9 (NGAL•MMP‐9) complex in the inflammatory response to infection in pregnancies complicated by preterm birth. American Journal Of Reproductive Immunology 2016, 76: 108-117. PMID: 27251223, PMCID: PMC4942349, DOI: 10.1111/aji.12523.
- Baumbusch MA, Buhimschi CS, Oliver EA, Zhao G, Thung S, Rood K, Buhimschi IA. High Mobility Group-Box 1 (HMGB1) levels are increased in amniotic fluid of women with intra-amniotic inflammation-determined preterm birth, and the source may be the damaged fetal membranes. Cytokine 2016, 81: 82-7. PMID: 26954343, PMCID: PMC4803598, DOI: 10.1016/j.cyto.2016.02.013.
- Werner EF, Hamel MS, Orzechowski K, Berghella V, Thung SF. Cost-effectiveness of transvaginal ultrasound cervical length screening in singletons without a prior preterm birth: an update. Am J Obstet Gynecol 2015, 213: 554.e1-6. PMID: 26071914, DOI: 10.1016/j.ajog.2015.06.020.
- Dulay AT, Buhimschi IA, Zhao G, Bahtiyar MO, Thung SF, Cackovic M, Buhimschi CS. Compartmentalization of acute phase reactants Interleukin-6, C-Reactive Protein and Procalcitonin as biomarkers of intra-amniotic infection and chorioamnionitis. Cytokine 2015, 76: 236-243. PMID: 25957466, PMCID: PMC4824401, DOI: 10.1016/j.cyto.2015.04.014.
- Kunkle CM, Hallock JL, Hu X, Blomquist J, Thung SF, Werner EF. Cost utility analysis of urethral bulking agents versus midurethral sling in stress urinary incontinence. Female Pelvic Med Reconstr Surg 2015, 21: 154-9. PMID: 25730435, DOI: 10.1097/SPV.0000000000000173.
- Washington CI, Jamshidi R, Thung SF, Nayeri UA, Caughey AB, Werner EF. Timing of postpartum intrauterine device placement: a cost-effectiveness analysis. Fertil Steril 2015, 103: 131-7. PMID: 25439838, DOI: 10.1016/j.fertnstert.2014.09.032.
- Pettker CM, Thung SF, Lipkind HS, Illuzzi JL, Buhimschi CS, Raab CA, Copel JA, Lockwood CJ, Funai EF. A comprehensive obstetric patient safety program reduces liability claims and payments. American Journal Of Obstetrics And Gynecology 2014, 211: 319-325. PMID: 24925798, DOI: 10.1016/j.ajog.2014.04.038.
- Schuster KM, Jenq GY, Thung SF, Hersh DC, Nunes J, Silverman DG, Horwitz LI. Electronic handoff instruments: a truly multidisciplinary tool? Journal Of The American Medical Informatics Association 2014, 21: e352-e357. PMID: 24553477, PMCID: PMC4173175, DOI: 10.1136/amiajnl-2013-002361.
- Cordero L, Thung S, Landon MB, Nankervis CA. Breast-feeding initiation in women with pregestational diabetes mellitus. Clin Pediatr (Phila) 2014, 53: 18-25. PMID: 23884968, DOI: 10.1177/0009922813496455.
- Thung SF, Landon MB. Fetal surveillance and timing of delivery in pregnancy complicated by diabetes mellitus. Clin Obstet Gynecol 2013, 56: 837-43. PMID: 24071732, DOI: 10.1097/GRF.0b013e3182a9e504.
- Werner EF, Savitz DA, Janevic TM, Ehsanipoor RM, Thung SF, Funai EF, Lipkind HS. Mode of Delivery and Neonatal Outcomes in Preterm, Small-for-Gestational-Age Newborns. Obstetrics And Gynecology 2012, 120: 560-564. PMID: 22914464, PMCID: PMC3739844, DOI: 10.1097/aog.0b013e318265b16c.
- Zuckerwise LC, Werner EF, Pettker CM, McMahon-Brown EK, Thung SF, Han CS. Pregestational Diabetes With Extreme Insulin Resistance. Obstetrics And Gynecology 2012, 120: 439-442. PMID: 22825259, DOI: 10.1097/aog.0b013e31824fd27d.
- Werner E, Han C, Burd I, Lipkind H, Copel J, Bahtiyar M, Thung S. Evaluating the cost‐effectiveness of prenatal surgery for myelomeningocele: a decision analysis. Ultrasound In Obstetrics And Gynecology 2012, 40: 158-164. PMID: 22511529, DOI: 10.1002/uog.11176.
- Nayeri UA, Werner EF, Han CS, Pettker CM, Funai EF, Thung SF. Antenatal lamivudine to reduce perinatal hepatitis B transmission: a cost-effectiveness analysis. American Journal Of Obstetrics And Gynecology 2012, 207: 231.e1-231.e7. PMID: 22939730, DOI: 10.1016/j.ajog.2012.06.001.
- Horwitz LI, Schuster KM, Thung SF, Hersh DC, Fisher RL, Shah N, Cushing W, Nunes J, Silverman DG, Jenq GY. An institution-wide handoff task force to standardise and improve physician handoffs. BMJ Quality & Safety 2012, 21: 863. PMID: 22626740, PMCID: PMC3463404, DOI: 10.1136/bmjqs-2011-000658.
- Werner EF, Pettker CM, Zuckerwise L, Reel M, Funai EF, Henderson J, Thung SF. Screening for Gestational Diabetes Mellitus: Are the Criteria Proposed by the International Association of the Diabetes and Pregnancy Study Groups Cost-Effective? Diabetes Care 2012, 35: 529-535. PMID: 22266735, PMCID: PMC3322683, DOI: 10.2337/dc11-1643.
- Chen HW, Bercik RS, Werner EF, Thung SF. Cost-Effectiveness of Percutaneous Tibial Nerve Stimulation Versus Extended Release Tolterodine for Overactive Bladder. Journal Of Urology 2011, 187: 178-184. PMID: 22100006, DOI: 10.1016/j.juro.2011.09.052.
- Buhimschi CS, Bhandari V, Dulay AT, Nayeri UA, Abdel-Razeq SS, Pettker CM, Thung S, Zhao G, Han YW, Bizzarro M, Buhimschi IA. Proteomics Mapping of Cord Blood Identifies Haptoglobin “Switch-On” Pattern as Biomarker of Early-Onset Neonatal Sepsis in Preterm Newborns. PLOS ONE 2011, 6: e26111. PMID: 22028810, PMCID: PMC3189953, DOI: 10.1371/journal.pone.0026111.
- Buhimschi CS, Buhimschi IA, Wehrum MJ, Molaskey-Jones S, Sfakianaki AK, Pettker CM, Thung S, Campbell KH, Dulay AT, Funai EF, Bahtiyar MO. Ultrasonographic Evaluation of Myometrial Thickness and Prediction of a Successful External Cephalic Version. Obstetrics And Gynecology 2011, 118: 913-920. PMID: 21934456, DOI: 10.1097/aog.0b013e31822e63fe.
- Werner EF, Han CS, Pettker CM, Buhimschi CS, Copel JA, Funai EF, Thung SF. Universal cervical‐length screening to prevent preterm birth: a cost‐effectiveness analysis. Ultrasound In Obstetrics And Gynecology 2011, 38: 32-37. PMID: 21157771, DOI: 10.1002/uog.8911.
- Lee SY, Buhimschi IA, Dulay AT, Ali UA, Zhao G, Abdel-Razeq SS, Bahtiyar MO, Thung SF, Funai EF, Buhimschi CS. IL-6 Trans-Signaling System in Intra-Amniotic Inflammation, Preterm Birth, and Preterm Premature Rupture of the Membranes. The Journal Of Immunology 2011, 186: 3226-3236. PMID: 21282511, PMCID: PMC3800180, DOI: 10.4049/jimmunol.1003587.
- Pettker CM, Thung SF, Raab CA, Donohue KP, Copel JA, Lockwood CJ, Funai EF. A comprehensive obstetrics patient safety program improves safety climate and culture. American Journal Of Obstetrics And Gynecology 2011, 204: 216.e1-216.e6. PMID: 21376160, DOI: 10.1016/j.ajog.2010.11.004.
- Wehrum MJ, Buhimschi IA, Salafia C, Thung S, Bahtiyar MO, Werner EF, Campbell KH, Laky C, Sfakianaki AK, Zhao G, Funai EF, Buhimschi CS. Accreta complicating complete placenta previa is characterized by reduced systemic levels of vascular endothelial growth factor and by epithelial-to-mesenchymal transition of the invasive trophoblast. American Journal Of Obstetrics And Gynecology 2011, 204: 411.e1-411.e11. PMID: 21316642, PMCID: PMC3136625, DOI: 10.1016/j.ajog.2010.12.027.
- Abdel-Razeq SS, Buhimschi IA, Bahtiyar MO, Rosenberg VA, Dulay AT, Han CS, Werner EF, Thung S, Buhimschi CS. Interpretation of Amniotic Fluid White Blood Cell Count in “Bloody Tap” Amniocenteses in Women With Symptoms of Preterm Labor. Obstetrics And Gynecology 2010, 116: 344-354. PMID: 20664395, PMCID: PMC4142228, DOI: 10.1097/aog.0b013e3181e8fec6.
- Buhimschi CS, Bhandari V, Dulay AT, Thung S, Razeq SS, Rosenberg V, Han CS, Ali UA, Zambrano E, Zhao G, Funai EF, Buhimschi IA. Amniotic fluid angiopoietin-1, angiopoietin-2, and soluble receptor tunica interna endothelial cell kinase-2 levels and regulation in normal pregnancy and intraamniotic inflammation-induced preterm birth. The Journal Of Clinical Endocrinology And Metabolism 2010, 95: 3428-36. PMID: 20410222, PMCID: PMC2928907, DOI: 10.1210/jc.2009-2829.
- Azpurua H, Norwitz ER, Campbell KH, Funai EF, Pettker CM, Kleine M, Bahtiyar MO, Malkus H, Copel JA, Thung SF. Acceleration/ejection time ratio in the fetal pulmonary artery predicts fetal lung maturity. American Journal Of Obstetrics And Gynecology 2010, 203: 40.e1-40.e8. PMID: 20417479, DOI: 10.1016/j.ajog.2010.01.075.
- Bulun SE, Cheng YH, Pavone ME, Xue Q, Attar E, Trukhacheva E, Tokunaga H, Utsunomiya H, Yin P, Luo X, Lin Z, Imir G, Thung S, Su EJ, Kim JJ. Estrogen receptor-beta, estrogen receptor-alpha, and progesterone resistance in endometriosis. Semin Reprod Med 2010, 28: 36-43. PMID: 20104427, DOI: 10.1055/s-0029-1242991.
- Bulun SE, Cheng YH, Pavone ME, Yin P, Imir G, Utsunomiya H, Thung S, Xue Q, Marsh EE, Tokunaga H, Ishikawa H, Kurita T, Su EJ. 17Beta-hydroxysteroid dehydrogenase-2 deficiency and progesterone resistance in endometriosis. Semin Reprod Med 2010, 28: 44-50. PMID: 20108182, DOI: 10.1055/s-0029-1242992.
- Thung SF, Norwitz ER. Postpartum care: we can and should do better. Am J Obstet Gynecol 2010, 202: 1-4. PMID: 20096251, DOI: 10.1016/j.ajog.2009.08.028.
- Pettker CM, Thung SF, Dulay A, Han C, Ali U. Discussion: ‘Predicting neonatal acidemia by computer analysis’ by Costa et al. American Journal Of Obstetrics And Gynecology 2009, 201: e1-e4. PMID: 19879389, DOI: 10.1016/j.ajog.2009.08.014.
- Richter CE, Saber S, Thung SF. Eclampsia complicated by abdominal compartment syndrome. Am J Perinatol 2009, 26: 751-3. PMID: 19444766, DOI: 10.1055/s-0029-1223289.
- Carlson A, Thung SF, Norwitz ER. H1N1 Influenza in Pregnancy: What All Obstetric Care Providers Ought to Know. Rev Obstet Gynecol 2009, 2: 139-45. PMID: 19826571.
- Thung SF, Funai EF, Grobman WA. The cost-effectiveness of universal screening in pregnancy for subclinical hypothyroidism. American Journal Of Obstetrics And Gynecology 2009, 200: 267.e1-7. PMID: 19114278, DOI: 10.1016/j.ajog.2008.10.035.
- Pettker CM, Thung SF, Norwitz ER, Buhimschi CS, Raab CA, Copel JA, Kuczynski E, Lockwood CJ, Funai EF. Impact of a comprehensive patient safety strategy on obstetric adverse events. American Journal Of Obstetrics And Gynecology 2009, 200: 492.e1-492.e8. PMID: 19249729, DOI: 10.1016/j.ajog.2009.01.022.
- Buhimschi IA, Zhao G, Rosenberg VA, Abdel-Razeq S, Thung S, Buhimschi CS. Multidimensional Proteomics Analysis of Amniotic Fluid to Provide Insight into the Mechanisms of Idiopathic Preterm Birth. PLOS ONE 2008, 3: e2049. PMID: 18431506, PMCID: PMC2315798, DOI: 10.1371/journal.pone.0002049.
- Utsunomiya H, Cheng YH, Lin Z, Reierstad S, Yin P, Attar E, Xue Q, Imir G, Thung S, Trukhacheva E, Suzuki T, Sasano H, Kim JJ, Yaegashi N, Bulun SE. Upstream stimulatory factor-2 regulates steroidogenic factor-1 expression in endometriosis. Mol Endocrinol 2008, 22: 904-14. PMID: 18165439, DOI: 10.1210/me.2006-0302.
- Dulay AT, Buhimschi IA, Zhao G, Luo G, Abdel-Razeq S, Cackovic M, Rosenberg VA, Pettker CM, Thung SF, Bahtiyar MO, Bhandari V, Buhimschi CS. Nucleated red blood cells are a direct response to mediators of inflammation in newborns with early-onset neonatal sepsis. American Journal Of Obstetrics And Gynecology 2008, 198: 426.e1-426.e9. PMID: 18395034, PMCID: PMC4023236, DOI: 10.1016/j.ajog.2008.01.040.
- Buhimschi C, Rosenberg V, Dulay A, Thung S, Sfakianaki A, Bahtiyar M, Buhimschi I. Multidimensional System Biology: Genetic Markers and Proteomic Biomarkers of Adverse Pregnancy Outcome in Preterm Birth. American Journal Of Perinatology 2008, 25: 175-187. PMID: 18425720, DOI: 10.1055/s-2008-1061497.
- Buhimschi IA, Zambrano E, Pettker CM, Bahtiyar MO, Paidas M, Rosenberg VA, Thung S, Salafia CM, Buhimschi CS. Using Proteomic Analysis of the Human Amniotic Fluid to Identify Histologic Chorioamnionitis. Obstetrics And Gynecology 2008, 111: 403-412. PMID: 18238979, DOI: 10.1097/aog.0b013e31816102aa.
- Yin P, Lin Z, Cheng YH, Marsh EE, Utsunomiya H, Ishikawa H, Xue Q, Reierstad S, Innes J, Thung S, Kim JJ, Xu E, Bulun SE. Progesterone receptor regulates Bcl-2 gene expression through direct binding to its promoter region in uterine leiomyoma cells. J Clin Endocrinol Metab 2007, 92: 4459-66. PMID: 17785366, DOI: 10.1210/jc.2007-0725.
- Bulun SE, Chen D, Lu M, Zhao H, Cheng Y, Demura M, Yilmaz B, Martin R, Utsunomiya H, Thung S, Su E, Marsh E, Hakim A, Yin P, Ishikawa H, Amin S, Imir G, Gurates B, Attar E, Reierstad S, Innes J, Lin Z. Aromatase excess in cancers of breast, endometrium and ovary. J Steroid Biochem Mol Biol 2007, 106: 81-96. PMID: 17590327, DOI: 10.1016/j.jsbmb.2007.05.027.
- Buhimschi CS, Buhimschi IA, Abdel-Razeq S, Rosenberg VA, Thung SF, Zhao G, Wang E, Bhandari V. Proteomic Biomarkers of Intra-amniotic Inflammation: Relationship with Funisitis and Early-onset Sepsis in the Premature Neonate. Pediatric Research 2007, 61: 318-324. PMID: 17314690, DOI: 10.1203/01.pdr.0000252439.48564.37.
- Buhimschi IA, Zhao G, Pettker CM, Bahtiyar MO, Magloire LK, Thung S, Fairchild T, Buhimschi CS. The receptor for advanced glycation end products (RAGE) system in women with intraamniotic infection and inflammation. American Journal Of Obstetrics And Gynecology 2007, 196: 181.e1-181.e13. PMID: 17306673, DOI: 10.1016/j.ajog.2006.09.001.
- Thung SF, Grobman WA. The cost effectiveness of empiric intravenous immunoglobulin for the antepartum treatment of fetal and neonatal alloimmune thrombocytopenia. Am J Obstet Gynecol 2005, 193: 1094-9. PMID: 16157118, DOI: 10.1016/j.ajog.2005.05.048.
- Bulun SE, Lin Z, Imir G, Amin S, Demura M, Yilmaz B, Martin R, Utsunomiya H, Thung S, Gurates B, Tamura M, Langoi D, Deb S. Regulation of aromatase expression in estrogen-responsive breast and uterine disease: from bench to treatment. Pharmacol Rev 2005, 57: 359-83. PMID: 16109840, DOI: 10.1124/pr.57.3.6.
- Bulun SE, Imir G, Utsunomiya H, Thung S, Gurates B, Tamura M, Lin Z. Aromatase in endometriosis and uterine leiomyomata. J Steroid Biochem Mol Biol 2005, 95: 57-62. PMID: 16024248, DOI: 10.1016/j.jsbmb.2005.04.012.
- Thung SF, Grobman WA. The cost-effectiveness of routine antenatal screening for maternal herpes simplex virus-1 and -2 antibodies. Am J Obstet Gynecol 2005, 192: 483-8. PMID: 15695991, DOI: 10.1016/j.ajog.2004.09.134.