Rohan Khera, MD, MS
Biography
Rohan Khera, MBBS (a medical degree awarded in several countries outside the U.S.), is a cardiologist who studies the use of data and artificial intelligence to determine the best therapies for patientswith heart issues.
His work explores the use of “digital phenotyping,” or data from devices like personal smartphones. The information found there—including data regarding activity, social interactions, and day-to-day behaviors—can be combined with information from patients’ electronic health records to determine treatment possibilities.
Often, physicians use a simple questionnaire to determine patient risk for cardiovascular issues. One of Dr. Khera’s studies suggests that using a patient’s electronic medical record can produce substantially more accurate predictions.
As leader of the Cardiovascular Data Science (CarDS) Lab, Dr. Khera heads a multidisciplinary group focused on data-driven learning in heart disease. Some of his work helps teams evaluate how accurately patients are diagnosed and treated. The group also designs new treatments and examines whether physicians follow what is considered best care.
Dr. Khera has published articles in leading medical journals, including The Journal of the American Medical Association, The BMJ, Circulation, andNature Communications.
Additionally, Dr. Khera has received numerous awards, including Young Investigator awards from the American College of Cardiology and the American Heart Association Resuscitation Science. The National Heart, Lung, and Blood Institute awarded Dr. Khera a career development grant to develop automated tools for better care for heart patients.
Titles
- Assistant Professor of Medicine (Cardiovascular Medicine) and of Biostatistics (Health Informatics)
- Clinical Director, Center for Health Informatics and Analytics, YNHH/Yale CORE
- Director, Cardiovascular Data Science Lab (CarDS)
Education & Training
- FellowshipUT Southwestern Medical Center (2020)
- MSUT Southwestern Medical Center (2019)
- Clinical ScholarUT Southwestern Medical Center (2019)
- ResidencyUniversity of Iowa Carver College of Medicine (2016)
- InternshipUniversity of Iowa Carver College of Medicine (2014)
- MDAll India Institute of Medical Sciences (2011)
Languages Spoken
- English
- हिन्दी (Hindi)
- ਪੰਜਾਬੀ (Punjabi)
Additional Information
- Fellow of the American College of Cardiology: American Heart Association (2024)
- Fellow of the American College of Cardiology: American College of Cardiology (2023)
- ACC Emerging Faculty Leadership Academy: American College of Cardiology (2023)
- Blavatnik Award: Blavatnik Family Fund (2023)
- Young Physician-Scientist Award: American Society for Clinical Investigation (ASCI) (2023)
- Clinical Scientist Development Award: Doris Duke Charitable Foundation (2022)
- Jeremiah Stamler Distinguished Young Investigator Research Award: (2021)
- Young Investigator Award: American College of Cardiology (2019)
- Young Investigator Award: American Heart Association Resuscitation Science (2018)
- Francois M. Abboud Internal Medicine Research Award: University of Iowa Carver College of Medicine (2015)
- AB of Preventive Medicine, Clinical Informatics (2024)
- American Heart Association (2024 - 2025): Member
- National Science Foundation (2024): NSF-NIH Smart Health and Biomedical Research in the Era of Artificial Intelligence and Advanced Data Science (SCH) | NSF - National Science Foundation
- UK Biobank (2024 - 2025): Expert
- AHA Scientific Sessions Late-Breaking Science Working Group (2024): Advisor
- American College of Cardiology (2024 - Present): Special Advisor for Artificial Intelligence
- JAMA (2023 - Present): Associate Editor
- Yale Task Force on Artificial Intelligence - YSM AI in Clinical Research Panel (2023 - 2024): Member
- Yale Task Force on Artificial Intelligence - YSM/YNHH AI in Clinical Practice Panel (2023 - 2024): Member
- Nature (2023 - Present): Reviewer
- Nature Medicine (2023 - Present): Reviewer
- Holste G, Oikonomou E, Mortazavi B, Coppi A, Faridi K, Miller E, Forrest J, McNamara R, Ohno-Machado L, Yuan N, Gupta A, Ouyang D, Krumholz H, Wang Z, Khera R. Severe aortic stenosis detection by deep learning applied to echocardiography. European Heart Journal 2023, 44: 4592-4604. PMID: 37611002, PMCID: PMC11004929, DOI: 10.1093/eurheartj/ehad456.
- Khera R, Dhingra L, Aminorroaya A, Li K, Zhou J, Arshad F, Blacketer C, Bowring M, Bu F, Cook M, Dorr D, Duarte-Salles T, DuVall S, Falconer T, French T, Hanchrow E, Horban S, Lau W, Li J, Liu Y, Lu Y, Man K, Matheny M, Mathioudakis N, McLemore M, Minty E, Morales D, Nagy P, Nishimura A, Ostropolets A, Pistillo A, Posada J, Pratt N, Reyes C, Ross J, Seager S, Shah N, Simon K, Wan E, Yang J, Yin C, You S, Schuemie M, Ryan P, Hripcsak G, Krumholz H, Suchard M. Multinational patterns of second line antihyperglycaemic drug initiation across cardiovascular risk groups: federated pharmacoepidemiological evaluation in LEGEND-T2DM. BMJ Medicine 2023, 2: e000651. PMID: 37829182, PMCID: PMC10565313, DOI: 10.1136/bmjmed-2023-000651.
- Khunte A, Sangha V, Oikonomou E, Dhingra L, Aminorroaya A, Mortazavi B, Coppi A, Brandt C, Krumholz H, Khera R. Detection of left ventricular systolic dysfunction from single-lead electrocardiography adapted for portable and wearable devices. Npj Digital Medicine 2023, 6: 124. PMID: 37433874, PMCID: PMC10336107, DOI: 10.1038/s41746-023-00869-w.
- Sangha V, Nargesi A, Dhingra L, Khunte A, Mortazavi B, Ribeiro A, Banina E, Adeola O, Garg N, Brandt C, Miller E, Ribeiro A, Velazquez E, Giatti L, Barreto S, Foppa M, Yuan N, Ouyang D, Krumholz H, Khera R. Detection of Left Ventricular Systolic Dysfunction From Electrocardiographic Images. Circulation 2023, 148: 765-777. PMID: 37489538, PMCID: PMC10982757, DOI: 10.1161/circulationaha.122.062646.
- Oikonomou EK, Spatz ES, Suchard MA, Khera R. Individualising intensive systolic blood pressure reduction in hypertension using computational trial phenomaps and machine learning: a post-hoc analysis of randomised clinical trials. The Lancet Digital Health 2022, 4: e796-e805. PMID: 36307193, PMCID: PMC9768739, DOI: 10.1016/s2589-7500(22)00170-4.
- Silva G, Khera R, Schwamm L, Acampa M, Adelman E, Boltze J, Broderick J, Brodtmann A, Christensen H, Dalli L, Duncan K, Elgendy I, Ergul A, Goldstein L, Hinkle J, Johansen M, Jood K, Kasner S, Levine S, Li Z, Lip G, Marsh E, Muir K, Ospel J, Pera J, Quinn T, Räty S, Ranta A, Richards L, Romero J, Willey J, Hillis A, Veerbeek J. Reviewer Experience Detecting and Judging Human Versus Artificial Intelligence Content: The Stroke Journal Essay Contest. Stroke 2024 PMID: 39224979, DOI: 10.1161/strokeaha.124.045012.
- Oikonomou E, Sangha V, Dhingra L, Aminorroaya A, Coppi A, Krumholz H, Baldassarre L, Khera R. Artificial Intelligence-Enhanced Risk Stratification of Cancer Therapeutics-Related Cardiac Dysfunction Using Electrocardiographic Images. Circulation Cardiovascular Quality And Outcomes 2024 PMID: 39221857, DOI: 10.1161/circoutcomes.124.011504.
- Khera R, Aminorroaya A, Dhingra L, Thangaraj P, Pedroso Camargos A, Bu F, Ding X, Nishimura A, Anand T, Arshad F, Blacketer C, Chai Y, Chattopadhyay S, Cook M, Dorr D, Duarte-Salles T, DuVall S, Falconer T, French T, Hanchrow E, Kaur G, Lau W, Li J, Li K, Liu Y, Lu Y, Man K, Matheny M, Mathioudakis N, McLeggon J, McLemore M, Minty E, Morales D, Nagy P, Ostropolets A, Pistillo A, Phan T, Pratt N, Reyes C, Richter L, Ross J, Ruan E, Seager S, Simon K, Viernes B, Yang J, Yin C, You S, Zhou J, Ryan P, Schuemie M, Krumholz H, Hripcsak G, Suchard M. Comparative Effectiveness of Second-Line Antihyperglycemic Agents for Cardiovascular Outcomes A Multinational, Federated Analysis of LEGEND-T2DM. Journal Of The American College Of Cardiology 2024, 84: 904-917. PMID: 39197980, DOI: 10.1016/j.jacc.2024.05.069.
- Jiang J, Thi Vy H, Charney A, Kovatch P, Reddy V, Jayaraman P, Do R, Khera R, Chugh S, Bhatt D, Vaid A, Lampert J, Nadkarni G. Multimodal fusion learning for long QT syndrome pathogenic genotypes in a racially diverse population. Npj Digital Medicine 2024, 7: 226. PMID: 39181999, PMCID: PMC11344778, DOI: 10.1038/s41746-024-01218-1.
- Zhou T, Sawano M, Arun A, Caraballo C, Michelsen T, McAlpine L, Bhattacharjee B, Lu Y, Khera R, Huang C, Warner F, Herrin J, Iwasaki A, Krumholz H. Internal tremors and vibrations in long COVID: a cross-sectional study. The American Journal Of Medicine 2024 PMID: 39069199, DOI: 10.1016/j.amjmed.2024.07.008.
- Khera R. AI-enabled diagnosis from an electrocardiogram image: the next frontier of innovation in a century-old technology. Heart 2024, 110: heartjnl-2024-324299. PMID: 39048290, PMCID: PMC11328242, DOI: 10.1136/heartjnl-2024-324299.
- Khera R, Aminorroaya A, Kennedy K, Chan P, Investigators A, Grossestreuer A, Moskowitz A, Ornato J, Churpek M, Starks M, Girotra S, Perman S. Correlation between hospital rates of survival to discharge and long-term survival for in-hospital cardiac arrest: Insights from Get With The Guidelines®-Resuscitation registry. Resuscitation 2024, 202: 110322. PMID: 39029583, PMCID: PMC11390317, DOI: 10.1016/j.resuscitation.2024.110322.
- Oikonomou E, Khera R. Designing medical artificial intelligence systems for global use: focus on interoperability, scalability, and accessibility. Hellenic Journal Of Cardiology 2024 PMID: 39025234, DOI: 10.1016/j.hjc.2024.07.003.
- Shimbo D, Shah R, Abdalla M, Agarwal R, Ahmad F, Anaya G, Attia Z, Bull S, Chang A, Commodore-Mensah Y, Ferdinand K, Kawamoto K, Khera R, Leopold J, Luo J, Makhni S, Mortazavi B, Oh Y, Savage L, Spatz E, Stergiou G, Turakhia M, Whelton P, Yancy C, Iturriaga E. Transforming Hypertension Diagnosis and Management in The Era of Artificial Intelligence: A 2023 National Heart, Lung, and Blood Institute (NHLBI) Workshop Report. Hypertension 2024 PMID: 39011653, DOI: 10.1161/hypertensionaha.124.22095.
- Oikonomou E, Khera R. Artificial intelligence-enhanced patient evaluation: bridging art and science. European Heart Journal 2024, 45: 3204-3218. PMID: 38976371, PMCID: PMC11400875, DOI: 10.1093/eurheartj/ehae415.
- Holste G, Oikonomou E, Mortazavi B, Wang Z, Khera R. Efficient deep learning-based automated diagnosis from echocardiography with contrastive self-supervised learning. Communications Medicine 2024, 4: 133. PMID: 38971887, PMCID: PMC11227494, DOI: 10.1038/s43856-024-00538-3.
- Khera R, Oikonomou E, Nadkarni G, Morley J, Wiens J, Butte A, Topol E. Transforming Cardiovascular Care With Artificial Intelligence: From Discovery to Practice JACC State-of-the-Art Review. Journal Of The American College Of Cardiology 2024, 84: 97-114. PMID: 38925729, DOI: 10.1016/j.jacc.2024.05.003.
- Arun A, Sawano M, Lu Y, Warner F, Caraballo C, Khera R, Echols M, Yancy C, Krumholz H. Excess Cardiovascular Mortality Among Black Americans 2000-2022. Journal Of The American College Of Cardiology 2024, 84: 581-588. PMID: 38901531, DOI: 10.1016/j.jacc.2024.06.004.
- Camargos A, Barreto S, Brant L, Ribeiro A, Dhingra L, Aminorroaya A, Bittencourt M, Figueiredo R, Khera R. Performance of contemporary cardiovascular risk stratification scores in Brazil: an evaluation in the ELSA-Brasil study. Open Heart 2024, 11: e002762. PMID: 38862252, PMCID: PMC11168182, DOI: 10.1136/openhrt-2024-002762.
- Oikonomou E, Holste G, Yuan N, Coppi A, McNamara R, Haynes N, Vora A, Velazquez E, Li F, Menon V, Kapadia S, Gill T, Nadkarni G, Krumholz H, Wang Z, Ouyang D, Khera R. A Multimodal Video-Based AI Biomarker for Aortic Stenosis Development and Progression. JAMA Cardiology 2024, 9: 534-544. PMID: 38581644, PMCID: PMC10999005, DOI: 10.1001/jamacardio.2024.0595.
- L’Italien G, Oikonomou E, Khera R, Potashman M, Beiner M, Maclaine G, Schmahmann J, Perlman S, Coric V. Video-Based Kinematic Analysis of Movement Quality in a Phase 3 Clinical Trial of Troriluzole in Adults with Spinocerebellar Ataxia: A Post Hoc Analysis. Neurology And Therapy 2024, 13: 1287-1301. PMID: 38814532, PMCID: PMC11263303, DOI: 10.1007/s40120-024-00625-6.
- Krumholz H, Sawano M, Bhattacharjee B, Caraballo C, Khera R, Li S, Herrin J, Coppi A, Holub J, Henriquez Y, Johnson M, Goddard T, Rocco E, Hummel A, Al Mouslmani M, Putrino D, Carr K, Carvajal-Gonzalez S, Charnas L, De Jesus M, Ziegler F, Iwasaki A. The PAX LC Trial: A Decentralized, Phase 2, Randomized, Double-blind Study of Nirmatrelvir/Ritonavir Compared with Placebo/Ritonavir for Long COVID. The American Journal Of Medicine 2024 PMID: 38735354, DOI: 10.1016/j.amjmed.2024.04.030.
- Aminorroaya A, Dhingra L, Oikonomou E, Saadatagah S, Thangaraj P, Vasisht Shankar S, Spatz E, Khera R. Development and multinational validation of an algorithmic strategy for high Lp(a) screening. Nature Cardiovascular Research 2024, 3: 558-566. PMID: 39195936, DOI: 10.1038/s44161-024-00469-1.
- Bibbins-Domingo K, Angus D, Park H, Lewis R, Khera R, Zeis J, Flanagin A, Curfman G. Introducing the JAMA Summit. JAMA 2024, 331: 1451-1451. DOI: 10.1001/jama.2024.5570.
- Vaid A, Duong S, Lampert J, Kovatch P, Freeman R, Argulian E, Croft L, Lerakis S, Goldman M, Khera R, Nadkarni G. Local large language models for privacy-preserving accelerated review of historic echocardiogram reports. Journal Of The American Medical Informatics Association 2024, 31: 2097-2102. PMID: 38687616, PMCID: PMC11339495, DOI: 10.1093/jamia/ocae085.
- Gonzalez P, Hebbe A, Hussain Y, Khera R, Banerjee S, Plomondon M, Waldo S, Pfau S, Curtis J, Shah S. Real-World Experience and Outcomes With Percutaneous Coronary Intervention for Protected Versus Unprotected Left Main Coronary Artery Disease: Insights from the Veteran Affairs Clinical Assessment Reporting and Tracking Program. The American Journal Of Cardiology 2024, 222: 39-50. PMID: 38677666, DOI: 10.1016/j.amjcard.2024.04.039.
- Beiner M, Oikonomou E, L’Italien G, Khera R, Potashman M, Schmahmann J, Perlman S, Coric V. Automated Video-based Characterization of Movement Quality in a Phase III Clinical Trial of Troriluzole in Subjects with Spinocerebellar Ataxia (P6-3.014). Neurology 2024, 102 DOI: 10.1212/wnl.0000000000205170.
- Oikonomou E, Aminorroaya A, Dhingra L, Partridge C, Velazquez E, Desai N, Krumholz H, Miller E, Khera R. Real-world evaluation of an algorithmic machine-learning-guided testing approach in stable chest pain: a multinational, multicohort study. European Heart Journal - Digital Health 2024, 5: 303-313. PMID: 38774380, PMCID: PMC11104476, DOI: 10.1093/ehjdh/ztae023.
- Jain S, Elias P, Poterucha T, Randazzo M, Lopez Jimenez F, Khera R, Perez M, Ouyang D, Pirruccello J, Salerno M, Einstein A, Avram R, Tison G, Nadkarni G, Natarajan V, Pierson E, Beecy A, Kumaraiah D, Haggerty C, Avari Silva J, Maddox T. Artificial Intelligence in Cardiovascular Care—Part 2: Applications JACC Review Topic of the Week. Journal Of The American College Of Cardiology 2024, 83: 2487-2496. PMID: 38593945, DOI: 10.1016/j.jacc.2024.03.401.
- Elias P, Jain S, Poterucha T, Randazzo M, Lopez Jimenez F, Khera R, Perez M, Ouyang D, Pirruccello J, Salerno M, Einstein A, Avram R, Tison G, Nadkarni G, Natarajan V, Pierson E, Beecy A, Kumaraiah D, Haggerty C, Avari Silva J, Maddox T. Artificial Intelligence for Cardiovascular Care—Part 1: Advances JACC Review Topic of the Week. Journal Of The American College Of Cardiology 2024, 83: 2472-2486. PMID: 38593946, DOI: 10.1016/j.jacc.2024.03.400.
- Saha A, Li S, de Lemos J, Pandey A, Bhatt D, Fonarow G, Nallamothu B, Wang T, Navar A, Peterson E, Matsouaka R, Bavry A, Das S, Grodin J, Khera R, Drazner M, Kumbhani D, Registry N. Characteristics of High-Performing Hospitals in Cardiogenic Shock Following Acute Myocardial Infarction. The American Journal Of Cardiology 2024, 221: 19-28. PMID: 38583700, DOI: 10.1016/j.amjcard.2024.04.002.
- Flanagin A, Pirracchio R, Khera R, Berkwits M, Hswen Y, Bibbins-Domingo K. Reporting Use of AI in Research and Scholarly Publication—JAMA Network Guidance. JAMA 2024, 331: 1096-1098. PMID: 38451540, DOI: 10.1001/jama.2024.3471.
- Aminorroaya A, Chan P, Kennedy K, Khera R. CORRELATION BETWEEN HOSPITAL RATES OF SURVIVAL TO DISCHARGE AND LONG-TERM SURVIVAL FOR IN-HOSPITAL CARDIAC ARREST: INSIGHTS FROM GET WITH THE GUIDELINES®RESUSCITATION. Journal Of The American College Of Cardiology 2024, 83: 2557. DOI: 10.1016/s0735-1097(24)04547-9.
- Dhingra L, Aminorroaya A, Oikonomou E, Sangha V, Khunte A, Khera R. A WEARABLE-ADAPTED ARTIFICIAL INTELLIGENCE ALGORITHM FOR HEART FAILURE PREDICTION FROM SINGLE-LEAD ELECTROCARDIOGRAMS IN A LARGE NATIONWIDE COHORT STUDY. Journal Of The American College Of Cardiology 2024, 83: 2341. DOI: 10.1016/s0735-1097(24)04331-6.
- Ahmed A, Agarwal R, Khera R, Liu Y, Sinusas A, Miller E, Feher A. A COMPARATIVE ANALYSIS OF PET, CZT SPECT, AND CONVENTIONAL SPECT IN MODERN CARDIOLOGY. Journal Of The American College Of Cardiology 2024, 83: 1365. DOI: 10.1016/s0735-1097(24)03355-2.
- Khaloo P, Wheelock K, Kapadia S, Khera R. TEMPORAL TRENDS IN ACCESS TO CARDIAC ELECTROPHYSIOLOGICAL CARE IN UNITED STATES: INSIGHT FROM US MEDICARE PHYSICIAN CLAIMS DATABASE (2013-2020). Journal Of The American College Of Cardiology 2024, 83: 29. DOI: 10.1016/s0735-1097(24)02019-9.
- Oikonomou E, Holste G, Nadkarni G, Wang Z, Khera R. CROSS-MODAL VALIDATION OF AN ARTIFICIAL INTELLIGENCE VIDEO-BASED APPROACH FOR THE AUTOMATED RISK STRATIFICATION OF AORTIC STENOSIS. Journal Of The American College Of Cardiology 2024, 83: 1418. DOI: 10.1016/s0735-1097(24)03408-9.
- Thangaraj P, Shankar S, Oikonomou E, Khera R. EVIDENCE FROM RANDOMIZED CONTROLLED TRIAL TO REAL-WORLD PATIENTS USING ELECTRONIC HEALTH RECORD-ADAPTED DIGITAL TWINS: A NOVEL APPLICATION OF GENERATIVE ARTIFICIAL INTELLIGENCE. Journal Of The American College Of Cardiology 2024, 83: 2340. DOI: 10.1016/s0735-1097(24)04330-4.
- Sangha V, Dhingra L, Aminorroaya A, Khera R. USING PHOTOS OF ELECTROCARDIOGRAMS AS A BIOMARKER FOR CARDIOVASCULAR RISK - A MULTINATIONAL ASSESSMENT OF A NOVEL ARTIFICIAL INTELLIGENCE APPROACH. Journal Of The American College Of Cardiology 2024, 83: 2443. DOI: 10.1016/s0735-1097(24)04433-4.
- Adejumo P, Dhingra L, Aminorroaya A, Khera R. A NOVEL DEEP LEARNING APPROACH FOR AUTOMATED EXTRACTION OF FUNCTIONAL STATUS AND NEW YORK HEART ASSOCIATION CLASS FOR HEART FAILURE PATIENTS DURING OUTPATIENT ENCOUNTERS. Journal Of The American College Of Cardiology 2024, 83: 313. DOI: 10.1016/s0735-1097(24)02303-9.
- Oikonomou E, Aminorroaya A, Dhingra L, Khera R. MULTINATIONAL REAL-WORLD EVALUATION OF A MACHINE LEARNING-DERIVED TOOL FOR ANATOMICAL VERSUS FUNCTIONAL TESTING IN SUSPECTED CORONARY ARTERY DISEASE. Journal Of The American College Of Cardiology 2024, 83: 1357. DOI: 10.1016/s0735-1097(24)03347-3.
- Dhingra L, Sangha V, Aminorroaya A, Camargos A, Oikonomou E, Khera R. HEART FAILURE RISK PREDICTION USING ARTIFICIAL INTELLIGENCE ON ECG PHOTOS IN LARGE CONTEMPORARY COHORT. Journal Of The American College Of Cardiology 2024, 83: 277. DOI: 10.1016/s0735-1097(24)02267-8.
- Feliciano K, Aminorroaya A, Dhingra L, Thangaraj P, Adejumo P, Khera R. WEARABLE DEVICE USE PATTERNS AMONG THOSE WITH CARDIOVASCULAR RISK IN ALL OF US RESEARCH PROGRAM: AN EVALUATION AGAINST A NATIONALLY REPRESENTATIVE DATABASE. Journal Of The American College Of Cardiology 2024, 83: 2045. DOI: 10.1016/s0735-1097(24)04035-x.
- Bansal B, Aminorroaya A, Dhingra L, Oikonomou E, Khera R. TRENDS IN KNOWLEDGE OF RISK FACTOR TARGETS AMONG PATIENTS WITH DIABETES MELLITUS IN THE UNITED STATES: A NATIONALLY REPRESENTATIVE STUDY. Journal Of The American College Of Cardiology 2024, 83: 1882. DOI: 10.1016/s0735-1097(24)03872-5.
- Khera R, Aminorroaya A, Dhingra L, Bu F, Camargos A, Falconer T, Zhou J, Dorr D, French T, Lau W, Lu Y, Blacketer C, Reyes C, Minty E, Li K, Man K, Ostropolets A, Nishimura A, Matheny M, Yang J, Ryan P, Y.F. W, Krumholz H, Hripcsak G, Suchard M. COMPARATIVE CARDIOVASCULAR EFFECTIVENESS OF ANTI-HYPERGLYCEMIC AGENTS INITIATED AS SECOND-LINE THERAPY IN TYPE 2 DIABETES: A LARGE-SCALE, MULTINATIONAL, FEDERATED TARGET TRIAL EMULATION IN THE LEGEND-T2DM STUDY. Journal Of The American College Of Cardiology 2024, 83: 1977. DOI: 10.1016/s0735-1097(24)03967-6.
- Sawano M, Khosla P, Arun A, Kaleem S, AL Mouslmani M, Caraballo C, Lu Y, Herrin J, Murugiah K, Khera R, Taylor H, Watson K, Yancy C, Krumholz H. EXCESS ISCHEMIC HEART DISEASE MORTALITY AND YEARS OF POTENTIAL LIFE LOST AMONG THE BLACK POPULATION: A TWO-DECADE ANALYSIS INCLUDING THE COVID-19 PANDEMIC. Journal Of The American College Of Cardiology 2024, 83: 1193. DOI: 10.1016/s0735-1097(24)03183-8.
- Lu Y, Arun A, Khosla P, Kaleem S, Sawano M, Herrin J, Caraballo C, Murugiah K, Khera R, Watson K, Taylor H, AL Mouslmani M, Krumholz H. HYPERTENSION EXCESS MORTALITY AND YEARS OF POTENTIAL LIFE LOST IN BLACK AMERICANS: A TWO-DECADE ANALYSIS INCLUDING THE COVID-19 PANDEMIC. Journal Of The American College Of Cardiology 2024, 83: 1675. DOI: 10.1016/s0735-1097(24)03665-9.
- Khera R. Artificial intelligence-enhanced exposomics: novel insights into cardiovascular health. European Heart Journal 2024, 45: 1550-1552. PMID: 38544282, DOI: 10.1093/eurheartj/ehae159.
- Khera R, Wiens J. Summertime for Cardiovascular AI. Circulation Cardiovascular Quality And Outcomes 2024, 17: e010404. PMID: 38502717, PMCID: PMC11117444, DOI: 10.1161/circoutcomes.123.010404.
- Oikonomou E, Khera R. Leveraging the Full Potential of Wearable Devices in Cardiomyopathies. Journal Of Cardiac Failure 2024, 30: 964-966. PMID: 38452997, DOI: 10.1016/j.cardfail.2024.02.011.
- Sangha V, Khunte A, Holste G, Mortazavi B, Wang Z, Oikonomou E, Khera R. Biometric contrastive learning for data-efficient deep learning from electrocardiographic images. Journal Of The American Medical Informatics Association 2024, 31: 855-865. PMID: 38269618, PMCID: PMC10990541, DOI: 10.1093/jamia/ocae002.
- Duong S, Vaid A, My V, Butler L, Lampert J, Pass R, Charney A, Narula J, Khera R, Sakhuja A, Greenspan H, Gelb B, Do R, Nadkarni G. Quantitative Prediction of Right Ventricular Size and Function From the ECG. Journal Of The American Heart Association 2023, 13: e031671. PMID: 38156471, PMCID: PMC10863807, DOI: 10.1161/jaha.123.031671.
- Khera R, Simon M, Ross J. Automation Bias and Assistive AI. JAMA 2023, 330: 2255-2257. PMID: 38112824, DOI: 10.1001/jama.2023.22557.
- Oikonomou E, Thangaraj P, Bhatt D, Ross J, Young L, Krumholz H, Suchard M, Khera R. An explainable machine learning-based phenomapping strategy for adaptive predictive enrichment in randomized clinical trials. Npj Digital Medicine 2023, 6: 217. PMID: 38001154, PMCID: PMC10673945, DOI: 10.1038/s41746-023-00963-z.
- Lu Y, Liu Y, Jastreboff A, Khera R, Ndumele C, Rodriguez F, Watson K, Krumholz H. Eligibility for Cardiovascular Risk Reduction Therapy in the United States Based on SELECT Trial Criteria: Insights From the National Health and Nutrition Examination Survey. Circulation Cardiovascular Quality And Outcomes 2023, 17: e010640. PMID: 37950677, PMCID: PMC10782930, DOI: 10.1161/circoutcomes.123.010640.
- Oikonomou E, Holste G, Mcnamara R, Velazquez E, Nadkarni G, Ouyang D, Krumholz H, Wang Z, Khera R. Predicting aortic stenosis progression using a video-based deep learning model of aortic stenosis built for single-view two-dimensional echocardiography. European Heart Journal 2023, 44: ehad655.040. DOI: 10.1093/eurheartj/ehad655.040.
- Sud M, Sivaswamy A, Austin P, Abdel-Qadir H, Anderson T, Khera R, Naimark D, Lee D, Roifman I, Thanassoulis G, Tu K, Wijeysundera H, Ko D. Validation of the European SCORE2 models in a Canadian primary care cohort. European Journal Of Preventive Cardiology 2023, 31: 668-676. PMID: 37946603, PMCID: PMC11025037, DOI: 10.1093/eurjpc/zwad352.
- Khaloo P, Wheelock K, Kapadia S, Khera R. Abstract 15725: Access to Pacemaker Implantation Amongst Medicare Beneficiaries: Travel Distance and Time to Nearest Clinician. Circulation 2023, 148: a15725-a15725. DOI: 10.1161/circ.148.suppl_1.15725.
- Nabi W, Aminorroaya A, Dhingra L, Khera R. Abstract 15485: Nationally Representative Trends of Overall Physical Activity and Its Subtypes Among US Adults With Diabetes, Hypertension, and Dyslipidemia: Findings From NHANES 2007-2020. Circulation 2023, 148: a15485-a15485. DOI: 10.1161/circ.148.suppl_1.15485.
- Pedroso A, Barreto S, Brant L, Ribeiro A, Bittencourt M, Figueiredo R, Khera R. Abstract 14328: Performance of Current Cardiovascular Risk Scores Among the Brazilian Population: Findings From the ELSA-Brasil Study. Circulation 2023, 148: a14328-a14328. DOI: 10.1161/circ.148.suppl_1.14328.
- Khunte A, Sangha V, Holste G, Dhingra L, Aminorroaya A, Wang Z, Khera R. Abstract 18776: ECG-GPT: Automated Complete Diagnosis Generation From ECG Images Using Novel Vision-Text Transformer Model. Circulation 2023, 148: a18776-a18776. DOI: 10.1161/circ.148.suppl_1.18776.
- Sangha V, Khunte A, Dhingra L, Oikonomou E, Khera R. Abstract 19045: Detection of Left Ventricular Systolic Dysfunction From PDF Outputs of ECGs Obtained on Wearable Devices. Circulation 2023, 148: a19045-a19045. DOI: 10.1161/circ.148.suppl_1.19045.
- Aminorroaya A, Dhingra L, Saadatagah S, Spatz E, Oikonomou E, Khera R. Abstract 17074: Development and Multinational Validation of a Machine Learning-Based Optimization for Efficient Screening for Elevated Lipoprotein(a). Circulation 2023, 148: a17074-a17074. DOI: 10.1161/circ.148.suppl_1.17074.
- Sangha V, Khunte A, Dhingra L, Oikonomou E, Khera R. Abstract 19135: Deep Learning Model for Detection of Conduction Disorders and Arrhythmias From PDF Outputs of Commercially Available Wearable Devices. Circulation 2023, 148: a19135-a19135. DOI: 10.1161/circ.148.suppl_1.19135.
- Khunte A, Aminorroaya A, Dhingra L, Sangha V, Oikonomou E, Sen S, Krumholz H, Kramer C, Desai M, Khera R. Abstract 17128: Detection of Hypertrophic Cardiomyopathy From Noisy Single-Lead Electrocardiography. Circulation 2023, 148: a17128-a17128. DOI: 10.1161/circ.148.suppl_1.17128.
- Kapadia S, Shen M, Hanna J, Wheelock K, Dhingra L, Khera R. Abstract 15414: Driving Distances and Durations to Nearest Transcatheter Aortic Valve Replacement Center for Medicare Beneficiaries Across Continental United States. Circulation 2023, 148: a15414-a15414. DOI: 10.1161/circ.148.suppl_1.15414.
- Dhingra L, Aminorroaya A, Oikonomou E, Sangha V, Krumholz H, Khera R. Abstract 17106: Comparing Pre- and Post- Pandemic Personal Health Monitoring Using Wearable Devices in United States Adults With or at Risk for Cardiovascular Disease: A Nationally Representative Study. Circulation 2023, 148: a17106-a17106. DOI: 10.1161/circ.148.suppl_1.17106.
- Aminorroaya A, Khunte A, Dhingra L, Sangha V, Sen S, Haynes N, Krumholz H, Khera R. Abstract 17098: Detection of Multiple Structural Heart Diseases Using a Novel Artificial Intelligence-Driven Algorithm for Noisy Real-World Single-Lead ECGs. Circulation 2023, 148: a17098-a17098. DOI: 10.1161/circ.148.suppl_1.17098.
- Dhingra L, Aminorroaya A, Khunte A, Sangha V, Sen S, Haynes N, Krumholz H, Khera R. Abstract 17094: An Ensemble Deep Learning Model to Automate Screening For Multiple Structural Heart Diseases on 12-Lead Electrocardiograms. Circulation 2023, 148: a17094-a17094. DOI: 10.1161/circ.148.suppl_1.17094.
- Dhingra L, Aminorroaya A, Khunte A, Sangha V, Oikonomou E, Sen S, Krumholz H, Kramer C, Desai M, Khera R. Abstract 17073: Evaluation of Impact of Septal Reduction Therapy on Deep Learning-Based Electrocardiographic Markers Hypertrophic Cardiomyopathy. Circulation 2023, 148: a17073-a17073. DOI: 10.1161/circ.148.suppl_1.17073.
- Nargesi A, Adejumo P, Rosand B, Dhingra L, Hengartner A, Sen S, Ahmad T, Ahmad F, Krumholz H, Khera R. Abstract 16207: Deep Learning-Based Natural Language Processing of Discharge Summaries for Automated Identification of Heart Failure With Reduced Ejection Fraction. Circulation 2023, 148: a16207-a16207. DOI: 10.1161/circ.148.suppl_1.16207.
- Oikonomou E, Thangaraj P, Bhatt D, Ross J, Young L, Krumholz H, Suchard M, Khera R. Abstract 15639: An Explainable Machine Learning-Based Phenomapping Strategy for Adaptive Predictive Enrichment in Randomized Controlled Trials of Preventive Interventions. Circulation 2023, 148: a15639-a15639. DOI: 10.1161/circ.148.suppl_1.15639.
- Sud M, Sivaswamy A, Austin P, Abdel-Qadir H, Anderson T, Khera R, Naimark D, Lee D, Roifman I, Thanassoulis G, Tu K, Wijeysundera H, Ko D. VALIDATION OF THE EUROPEAN SCORE2 MODELS IN A CANADIAN PRIMARY CARE COHORT. Canadian Journal Of Diabetes 2023, 47: s206. DOI: 10.1016/j.jcjd.2023.10.385.
- Thangaraj P, Khera R. Accelerating chest pain evaluation with machine learning. European Heart Journal Acute Cardiovascular Care 2023, 12: 753-754. PMID: 37793075, PMCID: PMC11004857, DOI: 10.1093/ehjacc/zuad117.
- Sud M, Sivaswamy A, Austin P, Abdel-Qadir H, Anderson T, Khera R, Naimark D, Lee D, Roifman I, Thanassoulis G, Tu K, Wijeysundera H, Ko D. VALIDATION OF THE EUROPEAN SCORE2 MODELS IN A CANADIAN PRIMARY CARE COHORT. Canadian Journal Of Cardiology 2023, 39: s248. DOI: 10.1016/j.cjca.2023.06.382.
- Oikonomou E, Khera R. Machine learning in precision diabetes care and cardiovascular risk prediction. Cardiovascular Diabetology 2023, 22: 259. PMID: 37749579, PMCID: PMC10521578, DOI: 10.1186/s12933-023-01985-3.
- Sandhu A, Khera R. Lifting the Veil on Advanced Heart Failure ∗. JACC Heart Failure 2023, 11: 1607-1610. PMID: 37737760, PMCID: PMC11009373, DOI: 10.1016/j.jchf.2023.07.031.
- Khera R, Butte A, Berkwits M, Hswen Y, Flanagin A, Park H, Curfman G, Bibbins-Domingo K. AI in Medicine—JAMA’s Focus on Clinical Outcomes, Patient-Centered Care, Quality, and Equity. JAMA 2023, 330: 818-820. PMID: 37566406, DOI: 10.1001/jama.2023.15481.
- Aminorroaya A, Dhingra L, Nargesi A, Oikonomou E, Krumholz H, Khera R. Use of Smart Devices to Track Cardiovascular Health Goals in the United States. JACC Advances 2023, 2: 100544. PMID: 38094515, PMCID: PMC10718569, DOI: 10.1016/j.jacadv.2023.100544.
- Dhingra L, Shen M, Mangla A, Khera R. Cardiovascular Care Innovation through Data-Driven Discoveries in the Electronic Health Record. The American Journal Of Cardiology 2023, 203: 136-148. PMID: 37499593, PMCID: PMC10865722, DOI: 10.1016/j.amjcard.2023.06.104.
- Zhang L, Khera R, Mortazavi B. Clinical Risk Prediction Models with Meta-Learning Prototypes of Patient Heterogeneity. Annual International Conference Of The IEEE Engineering In Medicine And Biology Society (EMBC) 2023, 00: 1-4. PMID: 38083199, PMCID: PMC11007255, DOI: 10.1109/embc40787.2023.10340765.
- See C, Wheelock K, Caraballo C, Khera R, Annapureddy A, Mahajan S, Lu Y, Krumholz H, Murugiah K. Patterns of Digoxin Prescribing for Medicare Beneficiaries in the United States 2013-2019. American Journal Of Medicine Open 2023, 10: 100048. PMID: 38213879, PMCID: PMC10783702, DOI: 10.1016/j.ajmo.2023.100048.
- Dhingra L, Aminorroaya A, Oikonomou E, Nargesi A, Wilson F, Krumholz H, Khera R. Use of Wearable Devices in Individuals With or at Risk for Cardiovascular Disease in the US, 2019 to 2020. JAMA Network Open 2023, 6: e2316634. PMID: 37285157, PMCID: PMC10248745, DOI: 10.1001/jamanetworkopen.2023.16634.
- Bejjani A, Khairani C, Lo Y, Jimenez D, Barco S, Mahajan S, Caraballo C, Klok E, Secemsky E, Aghayev A, Hunsaker A, Hussain M, Appah-Sampong A, Khera R, Goldhaber S, Zhou L, Monreal M, Krumholz H, Piazza G, Bikdeli B. Abstract 379: The Accuracy Of ICD-10 Discharge Diagnosis Codes For Identification Of Isolated Sub-Segmental Pulmonary Embolism: A PE-EHR+ Substudy. Arteriosclerosis Thrombosis And Vascular Biology 2023, 43 DOI: 10.1161/atvb.43.suppl_1.379.
- Sawano M, Lu Y, Caraballo C, Mahajan S, Dreyer R, Lichtman J, D'Onofrio G, Spatz E, Khera R, Onuma O, Murugiah K, Spertus J, Krumholz H. Sex Difference in Outcomes of Acute Myocardial Infarction in Young Patients. Journal Of The American College Of Cardiology 2023, 81: 1797-1806. PMID: 37137590, DOI: 10.1016/j.jacc.2023.03.383.
- Demkowicz P, Dhruva S, Spatz E, Beatty A, Ross J, Khera R. Physician responses to apple watch-detected irregular rhythm alerts. American Heart Journal 2023, 262: 29-37. PMID: 37084933, PMCID: PMC10988207, DOI: 10.1016/j.ahj.2023.04.008.
- Nargesi A, Clark C, Aminorroaya A, Chen L, Liu M, Reddy A, Amodeo S, Oikonomou E, Suchard M, McGuire D, Lin Z, Inzucchi S, Khera R. Persistence on Novel Cardioprotective Antihyperglycemic Therapies in the United States. The American Journal Of Cardiology 2023, 196: 89-98. PMID: 37012183, PMCID: PMC11007258, DOI: 10.1016/j.amjcard.2023.03.002.
- Bikdeli B, Lo Y, Khairani C, Bejjani A, Jimenez D, Barco S, Mahajan S, Caraballo C, Secemsky E, Klok F, Hunsaker A, Aghayev A, Muriel A, Wang Y, Hussain M, Appah-Sampong A, Lu Y, Lin Z, Aneja S, Khera R, Goldhaber S, Zhou L, Monreal M, Krumholz H, Piazza G. Developing Validated Tools to Identify Pulmonary Embolism in Electronic Databases: Rationale and Design of the PE-EHR+ Study. Thrombosis And Haemostasis 2023, 123: 649-662. PMID: 36809777, PMCID: PMC11200175, DOI: 10.1055/a-2039-3222.
- Khera R, Kondamudi N, Liu M, Ayers C, Spatz E, Rao S, Essien U, Powell-Wiley T, Nasir K, Das S, Capers Q, Pandey A. Lifetime healthcare expenses across demographic and cardiovascular risk groups: The application of a novel modeling strategy in a large multiethnic cohort study. American Journal Of Preventive Cardiology 2023, 14: 100493. PMID: 37397263, PMCID: PMC10314135, DOI: 10.1016/j.ajpc.2023.100493.
- Chui P, Lan Z, Freeman J, Enriquez A, Khera R, Akar J, Masoudi F, Ong E, Curtis J. Variation in hospital use of cardiac resynchronization therapy-defibrillator among eligible patients and association with clinical outcomes. Heart Rhythm 2023, 20: 1000-1008. PMID: 36963741, DOI: 10.1016/j.hrthm.2023.03.022.
- Liu Y, Herrin J, Huang C, Khera R, Dhingra L, Dong W, Mortazavi B, Krumholz H, Lu Y. Nonexercise machine learning models for maximal oxygen uptake prediction in national population surveys. Journal Of The American Medical Informatics Association 2023, 30: 943-952. PMID: 36905605, PMCID: PMC10114129, DOI: 10.1093/jamia/ocad035.
- Lu Y, Linderman G, Mahajan S, Liu Y, Huang C, Khera R, Mortazavi B, Spatz E, Krumholz H. Quantifying Blood Pressure Visit-to-Visit Variability in the Real-World Setting: A Retrospective Cohort Study. Circulation Cardiovascular Quality And Outcomes 2023, 16: e009258. PMID: 36883456, DOI: 10.1161/circoutcomes.122.009258.
- Khunte A, Sangha V, Dhingra L, Oikonomou E, Mortazavi B, Khera R. DEEP LEARNING-BASED DETECTION OF LEFT VENTRICULAR SYSTOLIC DYSFUNCTION FROM NOISY SINGLE LEAD ELECTROCARDIOGRAPHY ADAPTED FOR WEARABLE DEVICES. Journal Of The American College Of Cardiology 2023, 81: 2262. DOI: 10.1016/s0735-1097(23)02706-7.
- Khera R, Loccoh E, Nguyen A, Li D, Chase L, Warraich H. MARKUP ON COMMON GENERIC MEDICATIONS AT HOSPITALS IN THE UNITED STATES: A NATIONALLY REPRESENTATIVE EVALUATION. Journal Of The American College Of Cardiology 2023, 81: 1667. DOI: 10.1016/s0735-1097(23)02111-3.
- Oikonomou E, Suchard M, Miller E, Velazquez E, Khera R. MECHANISTIC EVALUATION OF AN AI-DRIVEN CLINICAL DECISION SUPPORT TOOL TO PERSONALIZE THE USE OF ANATOMICAL TESTING IN SUSPECTED CORONARY ARTERY DISEASE. Journal Of The American College Of Cardiology 2023, 81: 1360. DOI: 10.1016/s0735-1097(23)01804-1.
- Sangha V, Khunte A, Holste G, Mortazavi B, Wang Z, Oikonomou E, Khera R. BIOMETRIC CONTRASTIVE MODELING FOR DATA-EFFICIENT DEEP LEARNING FROM ELECTROCARDIOGRAPHIC IMAGES. Journal Of The American College Of Cardiology 2023, 81: 2403. DOI: 10.1016/s0735-1097(23)02847-4.
- Sangha V, Oikonomou E, Khunte A, Gupta K, Mortazavi B, Khera R. SMART-AS: A NOVEL ARTIFICIAL INTELLIGENCE TOOL TO DETECT SEVERE AORTIC STENOSIS FROM ELECTROCARDIOGRAPHIC IMAGES. Journal Of The American College Of Cardiology 2023, 81: 2409. DOI: 10.1016/s0735-1097(23)02853-x.
- Nargesi A, Rosand B, Hengartner A, Adejumo P, Khera R. DEEP LEARNING-BASED IDENTIFICATION OF HEART FAILURE WITH REDUCED EJECTION FRACTION IN CLINICAL DOCUMENTATION TO AUTOMATE CARE QUALITY ASSESSMENT IN HEART FAILURE. Journal Of The American College Of Cardiology 2023, 81: 2302. DOI: 10.1016/s0735-1097(23)02746-8.
- Khera R, Dhingra L, Li K, Aminorroaya A, Zhou J, Arshad F, Bu F, Dorr D, Falconer T, French T, Lau W, Lu Y, Man K, Matheny M, Minty E, Nishimura A, Ostropolets A, Seager S, Y.F. W, Yang J, Yin C, Hripcsak G, Krumholz H. MULTINATIONAL PATTERNS OF SECOND-LINE ANTI-HYPERGLYCEMIC DRUG INITIATION IN ESTABLISHED CARDIOVASCULAR DISEASE: A FEDERATED PHARMACOEPIDEMIOLOGIC EVALUATION IN LEGEND-T2DM. Journal Of The American College Of Cardiology 2023, 81: 1646. DOI: 10.1016/s0735-1097(23)02090-9.
- Sawano M, Lu Y, Caraballo C, Mahajan S, Dreyer R, Lichtman J, D'Onofrio G, Spatz E, Khera R, Onuma O, Murugiah K, Spertus J, Krumholz H. SEX DIFFERENCE IN CAUSES AND TIMING OF ONE-YEAR OUTCOMES AMONG YOUNG ACUTE MYOCARDIAL INFARCTION PATIENTS; RESULTS FROM THE VIRGO STUDY. Journal Of The American College Of Cardiology 2023, 81: 1294. DOI: 10.1016/s0735-1097(23)01738-2.
- Oikonomou E, Spatz E, Ross J, Suchard M, Krumholz H, Khera R. A MACHINE LEARNING-GUIDED APPROACH FOR ADAPTIVE TRIAL ENRICHMENT AND ACCELERATION OF CARDIOVASCULAR OUTCOME TRIALS: INSIGHTS FROM THE SPRINT AND ACCORD-BP TRIALS. Journal Of The American College Of Cardiology 2023, 81: 2314. DOI: 10.1016/s0735-1097(23)02758-4.
- Nabi W, Aminorroaya A, Khera R. Abstract P445: Patterns in Physical Activity Among Individuals With Cardiovascular Risk Factors in the United States: A Population-Based Contemporary Study From NHANES 2017- 2020. Circulation 2023, 147: ap445-ap445. DOI: 10.1161/circ.147.suppl_1.p445.
- MCCLOSKEY V, Nasir K, Khera R, Oikonomou E, Diaz R, Kenney R, Aguilar R, Gulati M, Cingolani O, Gluckman T, Blankstein R, Hernandez M, Rivera J. Abstract 60: Impact of a Multisite, Protocol-Driven, Nurse Practitioner-Led, Cardiovascular Prevention Program in a Hispanic Medicare Advantage Population at High Risk for ASCVD: Healthy Heart Program at Cano Health. Circulation 2023, 147: a60-a60. DOI: 10.1161/circ.147.suppl_1.60.
- Loccoh E, Khera R, van Meijgaard J, Marsh T, Warraich H. Hospital Adherence to the Federal Price Transparency Mandate: Results from a Nationally Representative Sample. Journal Of General Internal Medicine 2023, 38: 2424-2427. PMID: 36650327, PMCID: PMC10406987, DOI: 10.1007/s11606-023-08039-0.
- Caraballo C, Mahajan S, Murugiah K, Mortazavi B, Lu Y, Khera R, Krumholz H. Timing of Blood Draws Among Patients Hospitalized in a Large Academic Medical Center. JAMA 2023, 329: 255-257. PMID: 36648476, PMCID: PMC9856620, DOI: 10.1001/jama.2022.21509.
- Valero-Elizondo J, Javed Z, Khera R, Tano M, Dudum R, Acquah I, Hyder A, Andrieni J, Sharma G, Blaha M, Virani S, Blankstein R, Cainzos-Achirica M, Nasir K. Unfavorable social determinants of health are associated with higher burden of financial toxicity among patients with atherosclerotic cardiovascular disease in the US: findings from the National Health Interview Survey. Archives Of Public Health 2022, 80: 248. PMID: 36474300, PMCID: PMC9727868, DOI: 10.1186/s13690-022-00987-z.
- Wheelock K, Chan P, Chen L, de Lemos J, Miller P, Nallamothu B, Girotra S, Khera R. Time in therapeutic range for targeted temperature management and outcomes following out-of-hospital cardiac arrest. Resuscitation 2022, 182: 109650. PMID: 36442596, PMCID: PMC9885789, DOI: 10.1016/j.resuscitation.2022.11.016.
- Agusala V, Dale P, Khera R, Brown S, Idris A, Link M, Mody P. Variation in coronary angiography use in Out-of-Hospital cardiac arrest. Resuscitation 2022, 181: 79-85. PMID: 36332772, DOI: 10.1016/j.resuscitation.2022.10.020.
- Shen M, Nargesi A, Nasir K, Bhatt DL, Khera R. Contemporary National Patterns of Eligibility and Use of Novel Lipid‐Lowering Therapies in the United States. Journal Of The American Heart Association 2022, 11: e026075. PMID: 36102276, PMCID: PMC9683659, DOI: 10.1161/jaha.122.026075.
- Siddiqi TJ, Ahmed A, Greene SJ, Shahid I, Usman MS, Oshunbade A, Alkhouli M, Hall ME, Murad MH, Khera R, Jain V, Van Spall HGC, Khan MS. Performance of current risk stratification models for predicting mortality in patients with heart failure: a systematic review and meta-analysis. European Journal Of Preventive Cardiology 2022, 29: 2027-2048. PMID: 35919956, DOI: 10.1093/eurjpc/zwac148.
- Mori M, Mark DB, Khera R, Lin H, Jones P, Huang C, Lu Y, Geirsson A, Velazquez EJ, Spertus JA, Krumholz HM. Identifying quality of life outcome patterns to inform treatment choices in ischemic cardiomyopathy. American Heart Journal 2022, 254: 12-22. PMID: 35932911, DOI: 10.1016/j.ahj.2022.07.007.
- Hanna J, Nargesi AA, Essien UR, Sangha V, Lin Z, Krumholz HM, Khera R. County-level variation in cardioprotective antihyperglycemic prescribing among medicare beneficiaries. American Journal Of Preventive Cardiology 2022, 11: 100370. PMID: 35968531, PMCID: PMC9364091, DOI: 10.1016/j.ajpc.2022.100370.
- Ali HR, Valero-Elizondo J, Wang SY, Cainzos-Achirica M, Bhimaraj A, Khan SU, Khan MS, Mossialos E, Khera R, Nasir K. Subjective Financial Hardship due to Medical Bills Among Patients With Heart Failure in the United States: The 2014–2018 Medical Expenditure Panel Survey. Journal Of Cardiac Failure 2022, 28: 1424-1433. PMID: 35839928, DOI: 10.1016/j.cardfail.2022.06.009.
- Wang SY, Valero-Elizondo J, Cainzos-Achirica M, Desai NR, Nasir K, Khera R. Measures of Financial Hardship From Health Care Expenses Among Families With a Member With Atherosclerotic Cardiovascular Disease in the US. JAMA Health Forum 2022, 3: e221962. PMID: 35977226, PMCID: PMC9308060, DOI: 10.1001/jamahealthforum.2022.1962.
- Khera R, Schuemie MJ, Lu Y, Ostropolets A, Chen R, Hripcsak G, Ryan PB, Krumholz HM, Suchard MA. Large-scale evidence generation and evaluation across a network of databases for type 2 diabetes mellitus (LEGEND-T2DM): a protocol for a series of multinational, real-world comparative cardiovascular effectiveness and safety studies. BMJ Open 2022, 12: e057977. PMID: 35680274, PMCID: PMC9185490, DOI: 10.1136/bmjopen-2021-057977.
- Minhas AMK, Sheikh AB, Ijaz SH, Mostafa A, Nazir S, Khera R, Loccoh EC, Warraich HJ. Rural-Urban Disparities in Heart Failure and Acute Myocardial Infarction Hospitalizations. The American Journal Of Cardiology 2022, 175: 164-169. PMID: 35577603, DOI: 10.1016/j.amjcard.2022.04.014.
- Pareek M, Steele J, Asnes J, Baldassarre L, Casale L, Desai N, Elder R, Faherty E, Ferguson I, Fishman R, Ghazizadeh Z, Glick L, Hall E, Khera R, Kokkinidis D, Kwan J, O'Marr J, Schussheim A, Tuohy E, Wang Y, Spatz E, Jacoby D, Miller E. Short-Term Outcomes After Myopericarditis Related to COVID-19 Vaccination. JACC Cardiovascular Imaging 2022, 15: 2002-2005. PMID: 36357140, PMCID: PMC9094612, DOI: 10.1016/j.jcmg.2022.03.026.
- Lu Y, Li SX, Liu Y, Rodriguez F, Watson KE, Dreyer RP, Khera R, Murugiah K, D’Onofrio G, Spatz ES, Nasir K, Masoudi FA, Krumholz HM. Sex-Specific Risk Factors Associated With First Acute Myocardial Infarction in Young Adults. JAMA Network Open 2022, 5: e229953. PMID: 35503221, PMCID: PMC9066284, DOI: 10.1001/jamanetworkopen.2022.9953.
- Sheppard J, Huang C, Mortazavi B, Schulz W, Krumholz H, Khera R. Abstract 242: Assessing Variation In Data Captured By Clinical Registries And The Electronic Health Record: Clinical Phenotypes Of Patients Undergoing Cardiac Catheterization. Circulation Cardiovascular Quality And Outcomes 2022, 15 DOI: 10.1161/circoutcomes.15.suppl_1.242.
- Hendren N, Peltz M, Khera R, Koch S, Young J, Starling R, Tang W, Pandey A, Drazner M, Grodin J. Association Between Center Level Characteristics And 1-Month Post-LVAD Implant Risk Standardized Mortality Rates. Journal Of Cardiac Failure 2022, 28: s59. DOI: 10.1016/j.cardfail.2022.03.151.
- Murugiah K, Chen L, Dreyer RP, Bouras G, Safdar B, Lu Y, Spatz ES, Gupta A, Khera R, Ng VG, Bueno H, Tweet MS, Spertus JA, Hayes SN, Lansky A, Krumholz HM. Depression and Perceived Stress After Spontaneous Coronary Artery Dissection and Comparison With Other Acute Myocardial Infarction (the VIRGO Experience). The American Journal Of Cardiology 2022, 173: 33-38. PMID: 35365290, PMCID: PMC9133198, DOI: 10.1016/j.amjcard.2022.03.005.
- Sangha V, Mortazavi BJ, Haimovich AD, Ribeiro AH, Brandt CA, Jacoby DL, Schulz WL, Krumholz HM, Ribeiro ALP, Khera R. Automated multilabel diagnosis on electrocardiographic images and signals. Nature Communications 2022, 13: 1583. PMID: 35332137, PMCID: PMC8948243, DOI: 10.1038/s41467-022-29153-3.
- Murugiah K, Chen L, Dreyer RP, Bouras G, Safdar B, Khera R, Lu Y, Spatz ES, Ng VG, Gupta A, Bueno H, Tweet MS, Spertus JA, Hayes SN, Lansky A, Krumholz HM. Health status outcomes after spontaneous coronary artery dissection and comparison with other acute myocardial infarction: The VIRGO experience. PLOS ONE 2022, 17: e0265624. PMID: 35320296, PMCID: PMC8942215, DOI: 10.1371/journal.pone.0265624.
- Khera R, Mortazavi BJ, Sangha V, Warner F, Patrick Young H, Ross JS, Shah ND, Theel ES, Jenkinson WG, Knepper C, Wang K, Peaper D, Martinello RA, Brandt CA, Lin Z, Ko AI, Krumholz HM, Pollock BD, Schulz WL. A multicenter evaluation of computable phenotyping approaches for SARS-CoV-2 infection and COVID-19 hospitalizations. Npj Digital Medicine 2022, 5: 27. PMID: 35260762, PMCID: PMC8904579, DOI: 10.1038/s41746-022-00570-4.
- Oikonomou EK, Suchard MA, McGuire DK, Khera R. Phenomapping-Derived Tool to Individualize the Effect of Canagliflozin on Cardiovascular Risk in Type 2 Diabetes. Diabetes Care 2022, 45: 965-974. PMID: 35120199, PMCID: PMC9016734, DOI: 10.2337/dc21-1765.
- Taha MB, Valero-Elizondo J, Yahya T, Caraballo C, Khera R, Patel KV, Ali HJR, Sharma G, Mossialos E, Cainzos-Achirica M, Nasir K. Cost-Related Medication Nonadherence in Adults With Diabetes in the United States: The National Health Interview Survey 2013-2018. Diabetes Care 2022, 45: 594-603. PMID: 35015860, DOI: 10.2337/dc21-1757.
- Wheelock KM, Ross JS, Murugiah K, Lin Z, Krumholz HM, Khera R. Clinician Trends in Prescribing Direct Oral Anticoagulants for US Medicare Beneficiaries. JAMA Network Open 2021, 4: e2137288. PMID: 34870678, PMCID: PMC8649845, DOI: 10.1001/jamanetworkopen.2021.37288.
- Khera R, Mortazavi BJ, Krumholz HM. Assessing Performance of Machine Learning—Reply. JAMA Cardiology 2021, 6: 1466-1466. PMID: 34586344, DOI: 10.1001/jamacardio.2021.3715.
- Sangha V, Lipska K, Lin Z, Inzucchi SE, McGuire DK, Krumholz HM, Khera R. Patterns of Prescribing Sodium-Glucose Cotransporter-2 Inhibitors for Medicare Beneficiaries in the United States. Circulation Cardiovascular Quality And Outcomes 2021, 14: e008381. PMID: 34779654, PMCID: PMC9022137, DOI: 10.1161/circoutcomes.121.008381.
- Fudim M, Zhong L, Patel KV, Khera R, Abdelmalek MF, Diehl AM, McGarrah RW, Molinger J, Moylan CA, Rao VN, Wegermann K, Neeland IJ, Halm EA, Das SR, Pandey A. Nonalcoholic Fatty Liver Disease and Risk of Heart Failure Among Medicare Beneficiaries. Journal Of The American Heart Association 2021, 10: e021654. PMID: 34755544, PMCID: PMC8751938, DOI: 10.1161/jaha.121.021654.
- Khera R. Digital Cardiovascular Epidemiology—Ushering in a New Era Through Computational Phenotyping of Cardiovascular Disease. JAMA Network Open 2021, 4: e2135561. PMID: 34807263, DOI: 10.1001/jamanetworkopen.2021.35561.
- Murugiah K, Chen L, Castro-Dominguez Y, Khera R, Krumholz HM. Scope of Practice of US Interventional Cardiologists from an Analysis of Medicare Billing Data. The American Journal Of Cardiology 2021, 160: 40-45. PMID: 34610872, DOI: 10.1016/j.amjcard.2021.08.041.
- Prasanna S, Premnath N, Angraal S, Sedhom R, Khera R, Parsons H, Hussaini S, Johnson P, Lou E, Beg M, Subbiah I, Rao P, Gupta A. Sentiment analysis of tweets on prior authorization. Journal Of Clinical Oncology 2021, 39: 322-322. DOI: 10.1200/jco.2020.39.28_suppl.322.
- Lago‐Hernandez C, Nguyen NH, Khera R, Loomba R, Asrani SK, Singh S. Financial Hardship From Medical Bills Among Adults With Chronic Liver Diseases: National Estimates From the United States. Hepatology 2021, 74: 1509-1522. PMID: 33772833, DOI: 10.1002/hep.31835.
- Mahajan S, Grandhi GR, Valero‐Elizondo J, Mszar R, Khera R, Acquah I, Yahya T, Virani SS, Blankstein R, Blaha MJ, Cainzos‐Achirica M, Nasir K. Scope and Social Determinants of Food Insecurity Among Adults With Atherosclerotic Cardiovascular Disease in the United States. Journal Of The American Heart Association 2021, 10: e020028. PMID: 34387089, PMCID: PMC8475063, DOI: 10.1161/jaha.120.020028.
- Thomas A, Valero-Elizondo J, Khera R, Warraich HJ, Reinhardt SW, Ali HJ, Nasir K, Desai NR. Forgone Medical Care Associated With Increased Health Care Costs Among the U.S. Heart Failure Population. JACC Heart Failure 2021, 9: 710-719. PMID: 34391737, DOI: 10.1016/j.jchf.2021.05.010.
- Secemsky EA, Butala N, Raja A, Khera R, Wang Y, Curtis JP, Maddox TM, Virani SS, Armstrong EJ, Shunk KA, Brindis RG, Bhatt D, Yeh RW. Comparative Outcomes of Percutaneous Coronary Intervention for ST-Segment–Elevation Myocardial Infarction Among Medicare Beneficiaries With Multivessel Coronary Artery Disease. Circulation Cardiovascular Interventions 2021, 14: e010323. PMID: 34372676, PMCID: PMC8485756, DOI: 10.1161/circinterventions.120.010323.
- Association of COVID-19 Hospitalization Volume and Case Growth at US Hospitals with Patient OutcomesKhera R, Liu Y, de Lemos JA, Das SR, Pandey A, Omar W, Kumbhani DJ, Girotra S, Yeh RW, Rutan C, Walchok J, Lin Z, Bradley SM, Velazquez EJ, Churchwell KB, Nallamothu BK, Krumholz HM, Curtis JP. Association of COVID-19 Hospitalization Volume and Case Growth at US Hospitals with Patient Outcomes. The American Journal Of Medicine 2021, 134: 1380-1388.e3. PMID: 34343515, PMCID: PMC8325555, DOI: 10.1016/j.amjmed.2021.06.034.
- Huo Z, Zhang L, Khera R, Huang S, Qian X, Wang Z, Mortazavi B. Sparse Gated Mixture-of-Experts to Separate and Interpret Patient Heterogeneity in EHR data. 2021, 00: 1-4. DOI: 10.1109/bhi50953.2021.9508549.
- Bradley SM, Emmons-Bell S, Mutharasan RK, Rodriguez F, Gupta D, Roth G, Gluckman TJ, Shah RU, Wang TY, Khera R, Peterson PN, Das S. Repeated cross-sectional analysis of hydroxychloroquine deimplementation in the AHA COVID-19 CVD Registry. Scientific Reports 2021, 11: 15097. PMID: 34302004, PMCID: PMC8302649, DOI: 10.1038/s41598-021-94203-7.
- Acquah I, Valero-Elizondo J, Javed Z, Ibrahim HN, Patel KV, Ryoo Ali HJ, Menser T, Khera R, Cainzos-Achirica M, Nasir K. Financial Hardship Among Nonelderly Adults With CKD in the United States. American Journal Of Kidney Diseases 2021, 78: 658-668. PMID: 34144103, DOI: 10.1053/j.ajkd.2021.04.011.
- Valero-Elizondo J, Chouairi F, Khera R, Grandhi GR, Saxena A, Warraich HJ, Virani SS, Desai NR, Sasangohar F, Krumholz HM, Esnaola NF, Nasir K. Atherosclerotic Cardiovascular Disease, Cancer, and Financial Toxicity Among Adults in the United States. JACC CardioOncology 2021, 3: 236-246. PMID: 34396329, PMCID: PMC8352280, DOI: 10.1016/j.jaccao.2021.02.006.
- Lago-Hernandez C, Nguyen NH, Khera R, Loomba R, Asrani SK, Singh S. Cost-Related Nonadherence to Medications Among US Adults With Chronic Liver Diseases. Mayo Clinic Proceedings 2021, 96: 2639-2650. PMID: 34120754, PMCID: PMC8492496, DOI: 10.1016/j.mayocp.2021.02.026.
- Rao A, Ranka S, Ayers C, Hendren N, Rosenblatt A, Alger HM, Rutan C, Omar W, Khera R, Gupta K, Mody P, DeFilippi C, Das SR, Hedayati SS, de Lemos JA. Association of Kidney Disease With Outcomes in COVID‐19: Results From the American Heart Association COVID‐19 Cardiovascular Disease Registry. Journal Of The American Heart Association 2021, 10: e020910. PMID: 34107743, PMCID: PMC8477855, DOI: 10.1161/jaha.121.020910.
- Khera R, Haimovich J, Hurley NC, McNamara R, Spertus JA, Desai N, Rumsfeld JS, Masoudi FA, Huang C, Normand SL, Mortazavi BJ, Krumholz HM. Use of Machine Learning Models to Predict Death After Acute Myocardial Infarction. JAMA Cardiology 2021, 6: 633-641. PMID: 33688915, PMCID: PMC7948114, DOI: 10.1001/jamacardio.2021.0122.
- Wang SY, Valero‐Elizondo J, Ali H, Pandey A, Cainzos‐Achirica M, Krumholz HM, Nasir K, Khera R. Out‐of‐pocket Annual Health Expenditures and Financial Toxicity from Healthcare Costs in Patients with Heart Failure in the United States. Journal Of The American Heart Association 2021, 10: e022164. PMID: 33998273, PMCID: PMC8483501, DOI: 10.1161/jaha.121.022164.
- Nargesi AA, Jeyashanmugaraja GP, Desai N, Lipska K, Krumholz H, Khera R. Contemporary National Patterns of Eligibility and Utilization of Novel Cardioprotective Anti‐hyperglycemic agents in Type 2 Diabetes. Journal Of The American Heart Association 2021, 10: e021084. PMID: 33998258, PMCID: PMC8403287, DOI: 10.1161/jaha.121.021084.
- Gupta A, Premnath N, Sedhom R, Beg MS, Khera R, Laheru DA, Dusetzina SB. Projected 30- day out-of-pocket costs and total spending on pancreatic enzyme replacement therapy under Medicare Part D. Pancreatology 2021, 21: 1009-1010. PMID: 34006458, DOI: 10.1016/j.pan.2021.05.002.
- Slavin SD, Khera R, Zafar SY, Nasir K, Warraich HJ. Financial burden, distress, and toxicity in cardiovascular disease. American Heart Journal 2021, 238: 75-84. PMID: 33961830, DOI: 10.1016/j.ahj.2021.04.011.
- Secemsky EA, Butala N, Raja A, Khera R, Wang Y, Curtis JP, Maddox TM, Virani SS, Armstrong EJ, Shunk KA, Brindis RG, Bhatt D, Yeh RW. Temporal Changes and Institutional Variation in Use of Percutaneous Coronary Intervention for ST-Elevation Myocardial Infarction With Multivessel Coronary Artery Disease in the United States. JAMA Cardiology 2021, 6: 574-580. PMID: 33146666, PMCID: PMC7643043, DOI: 10.1001/jamacardio.2020.5354.
- Oikonomou EK, Van Dijk D, Parise H, Suchard MA, de Lemos J, Antoniades C, Velazquez EJ, Miller EJ, Khera R. A phenomapping-derived tool to personalize the selection of anatomical vs. functional testing in evaluating chest pain (ASSIST). European Heart Journal 2021, 42: 2536-2548. PMID: 33881513, PMCID: PMC8488385, DOI: 10.1093/eurheartj/ehab223.
- Kunitomo Y, Thomas A, Chouairi F, Canavan ME, Kochar A, Khera R, Katz JN, Murphy C, Jentzer J, Ahmad T, Desai NR, Brennan J, Miller PE. Electronic health record risk score provides earlier prognostication of clinical outcomes in patients admitted to the cardiac intensive care unit. American Heart Journal 2021, 238: 85-88. PMID: 33891906, DOI: 10.1016/j.ahj.2021.04.004.
- Rosario K, Mehta A, Ayers C, Gonzalez P, Pandey A, Khera R, Kaplan R, Blaha MJ, Khera A, Blumenthal RS, Nasir K, Rodriguez CJ, Joshi PH. Performance of the Pooled Cohort Equations in Hispanic Individuals Across the United States: Insights From the Multi‐Ethnic Study of Atherosclerosis and the Dallas Heart Study. Journal Of The American Heart Association 2021, 10: e018410. PMID: 33870702, PMCID: PMC8200750, DOI: 10.1161/jaha.120.018410.
- Yang DX, Khera R, Miccio JA, Jairam V, Chang E, Yu JB, Park HS, Krumholz HM, Aneja S. Prevalence of Missing Data in the National Cancer Database and Association With Overall Survival. JAMA Network Open 2021, 4: e211793. PMID: 33755165, PMCID: PMC7988369, DOI: 10.1001/jamanetworkopen.2021.1793.
- Khera R, Clark C, Lu Y, Guo Y, Ren S, Truax B, Spatz ES, Murugiah K, Lin Z, Omer SB, Vojta D, Krumholz HM. Association of Angiotensin‐Converting Enzyme Inhibitors and Angiotensin Receptor Blockers with the Risk of Hospitalization and Death in Hypertensive Patients with Coronavirus Disease‐19. Journal Of The American Heart Association 2021, 10: e018086. PMID: 33624516, PMCID: PMC8403305, DOI: 10.1161/jaha.120.018086.
- Angraal S, Zachariah AG, Raaisa R, Khera R, Rao P, Krumholz HM, Spertus JA. Evaluation of Internet-Based Crowdsourced Fundraising to Cover Health Care Costs in the United States. JAMA Network Open 2021, 4: e2033157. PMID: 33427882, PMCID: PMC7801937, DOI: 10.1001/jamanetworkopen.2020.33157.
- Hendren NS, de Lemos JA, Ayers C, Das SR, Rao A, Carter S, Rosenblatt A, Walchok J, Omar W, Khera R, Hegde AA, Drazner MH, Neeland IJ, Grodin JL. Association of Body Mass Index and Age With Morbidity and Mortality in Patients Hospitalized With COVID-19. Circulation 2020, 143: 135-144. PMID: 33200947, DOI: 10.1161/circulationaha.120.051936.
- Mori M, Khera R. Pumping the Breaks on Health Care Costs of Cardiac Surgery by Focusing on Postacute Care Spending. Circulation Cardiovascular Quality And Outcomes 2020, 13: e007253. PMID: 33176464, DOI: 10.1161/circoutcomes.120.007253.
- Mszar R, Mahajan S, Valero-Elizondo J, Yahya T, Sharma R, Grandhi GR, Khera R, Virani SS, Lichtman J, Khan SU, Cainzos-Achirica M, Vahidy FS, Krumholz HM, Nasir K. Association Between Sociodemographic Determinants and Disparities in Stroke Symptom Awareness Among US Young Adults. Stroke 2020, 51: 3552-3561. PMID: 33100188, DOI: 10.1161/strokeaha.120.031137.
- Nguyen NH, Khera R, Dulai PS, Boland BS, Ohno-Machado L, Sandborn WJ, Singh S. National Estimates of Financial Hardship From Medical Bills and Cost-related Medication Nonadherence in Patients With Inflammatory Bowel Diseases in the United States. Inflammatory Bowel Diseases 2020, 27: 1068-1078. PMID: 33051681, PMCID: PMC8205631, DOI: 10.1093/ibd/izaa266.
- Mori M, Wang Y, Murugiah K, Khera R, Gupta A, Vallabhajosyula P, Masoudi FA, Geirsson A, Krumholz HM. Trends in Reoperative Coronary Artery Bypass Graft Surgery for Older Adults in the United States, 1998 to 2017. Journal Of The American Heart Association 2020, 9: e016980. PMID: 33045889, PMCID: PMC7763387, DOI: 10.1161/jaha.120.016980.
- Khera R, Pandey A, Ayers CR, Carnethon MR, Greenland P, Ndumele CE, Nambi V, Seliger SL, Chaves PHM, Safford MM, Cushman M, Xanthakis V, Ramachandran V, Mentz RJ, Correa A, Lloyd-Jones DM, Berry JD, de Lemos JA, Neeland IJ. Performance of the Pooled Cohort Equations to Estimate Atherosclerotic Cardiovascular Disease Risk by Body Mass Index. JAMA Network Open 2020, 3: e2023242. PMID: 33119108, PMCID: PMC7596579, DOI: 10.1001/jamanetworkopen.2020.23242.
- Khera R, Kondamudi N, Zhong L, Vaduganathan M, Parker J, Das SR, Grodin JL, Halm EA, Berry JD, Pandey A. Temporal Trends in Heart Failure Incidence Among Medicare Beneficiaries Across Risk Factor Strata, 2011 to 2016. JAMA Network Open 2020, 3: e2022190. PMID: 33095250, PMCID: PMC7584929, DOI: 10.1001/jamanetworkopen.2020.22190.
- Khera R, Secemsky EA, Wang Y, Desai NR, Krumholz HM, Maddox TM, Shunk KA, Virani SS, Bhatt DL, Curtis J, Yeh RW. Revascularization Practices and Outcomes in Patients With Multivessel Coronary Artery Disease Who Presented With Acute Myocardial Infarction and Cardiogenic Shock in the US, 2009-2018. JAMA Internal Medicine 2020, 180: 1317-1327. PMID: 32833024, PMCID: PMC9377424, DOI: 10.1001/jamainternmed.2020.3276.
- Martinez-Amezcua P, Haque W, Khera R, Kanaya AM, Sattar N, Lam CSP, Harikrishnan S, Shah SJ, Kandula NR, Jose PO, Narayan KMV, Agyemang C, Misra A, Jenum AK, Bilal U, Nasir K, Cainzos-Achirica M. The Upcoming Epidemic of Heart Failure in South Asia. Circulation Heart Failure 2020, 13: e007218. PMID: 32962410, DOI: 10.1161/circheartfailure.120.007218.
- Khera R, Valero-Elizondo J, Nasir K. Financial Toxicity in Atherosclerotic Cardiovascular Disease in the United States: Current State and Future Directions. Journal Of The American Heart Association 2020, 9: e017793. PMID: 32924728, PMCID: PMC7792407, DOI: 10.1161/jaha.120.017793.
- Murugiah K, Annapureddy AR, Khera R, Lansky A, Curtis JP. Characteristics of cardiac catheterization laboratory directors at the 2017 U.S. News & World Report top 100 U.S. cardiovascular hospitals. Catheterization And Cardiovascular Interventions 2020, 97: e624-e626. PMID: 32833350, DOI: 10.1002/ccd.29217.
- Nasir K, Khera R. Digital Phenotyping of Myocardial Dysfunction With 12-Lead ECG Tiptoeing Into the Future With Machine Learning ∗. Journal Of The American College Of Cardiology 2020, 76: 942-944. PMID: 32819468, DOI: 10.1016/j.jacc.2020.07.001.
- Financial Hardship After Traumatic Injury: Risk Factors and Drivers of Out-of-Pocket Health ExpensesO'Neill KM, Jean RA, Gross CP, Becher RD, Khera R, Elizondo JV, Nasir K. Financial Hardship After Traumatic Injury: Risk Factors and Drivers of Out-of-Pocket Health Expenses. Journal Of Surgical Research 2020, 256: 1-12. PMID: 32663705, DOI: 10.1016/j.jss.2020.05.095.
- Mori M, Khera R, Lin Z, Ross JS, Schulz W, Krumholz HM. The Promise of Big Data and Digital Solutions in Building a Cardiovascular Learning System: Opportunities and Barriers. Methodist DeBakey Cardiovascular Journal 2020, 16: 212-219. PMID: 33133357, PMCID: PMC7587314, DOI: 10.14797/mdcj-16-3-212.
- Caraballo C, Khera R, Jones PG, Decker C, Schulz W, Spertus JA, Krumholz HM. Rates and Predictors of Patient Underreporting of Hospitalizations During Follow-Up After Acute Myocardial Infarction. Circulation Cardiovascular Quality And Outcomes 2020, 13: e006231. PMID: 32552061, PMCID: PMC9465954, DOI: 10.1161/circoutcomes.119.006231.
- Nguyen NH, Khera R, Ohno-Machado L, Sandborn WJ, Singh S. Prevalence and Effects of Food Insecurity and Social Support on Financial Toxicity in and Healthcare Use by Patients With Inflammatory Bowel Diseases. Clinical Gastroenterology And Hepatology 2020, 19: 1377-1386.e5. PMID: 32526341, PMCID: PMC7987215, DOI: 10.1016/j.cgh.2020.05.056.
- Khera R, Dhingra LS, Jain S, Krumholz HM. An Evaluation of the Vulnerable Physician Workforce in the USA During the Coronavirus Disease-19 Pandemic. Journal Of General Internal Medicine 2020, 35: 3114-3116. PMID: 32495101, PMCID: PMC7269617, DOI: 10.1007/s11606-020-05854-7.
- Grandhi GR, Valero-Elizondo J, Mszar R, Brandt EJ, Annapureddy A, Khera R, Saxena A, Virani SS, Blankstein R, Desai NR, Blaha MJ, Cheema FH, Vahidy FS, Nasir K. Association of cardiovascular risk factor profile and financial hardship from medical bills among non-elderly adults in the United States. American Journal Of Preventive Cardiology 2020, 2: 100034. PMID: 34327457, PMCID: PMC8315456, DOI: 10.1016/j.ajpc.2020.100034.
- Khera R. Do or Do Not, There Is No Try. Circulation Cardiovascular Quality And Outcomes 2020, 13: e006693. PMID: 32393124, DOI: 10.1161/circoutcomes.120.006693.
- Mszar R, Grandhi GR, Valero‐Elizondo J, Caraballo C, Khera R, Desai N, Virani SS, Blankstein R, Blaha MJ, Nasir K. Cumulative Burden of Financial Hardship From Medical Bills Across the Spectrum of Diabetes Mellitus and Atherosclerotic Cardiovascular Disease Among Non‐Elderly Adults in the United States. Journal Of The American Heart Association 2020, 9: e015523. PMID: 32394783, PMCID: PMC7660844, DOI: 10.1161/jaha.119.015523.
- Khera R, Girotra S. Cerebral Embolic Protection Devices in Transcatheter Aortic Valve Replacement—Effective in Stroke Prevention? JAMA Internal Medicine 2020, 180: 785-786. PMID: 32091530, DOI: 10.1001/jamainternmed.2019.6763.
- Jain S, Khera R, Lin Z, Ross JS, Krumholz HM. Availability of Telemedicine Services Across Hospitals in the United States in 2018: A Cross-sectional Study. Annals Of Internal Medicine 2020, 173: m20-1201. PMID: 32353106, PMCID: PMC7212823, DOI: 10.7326/m20-1201.
- Caraballo C, Valero-Elizondo J, Khera R, Mahajan S, Grandhi GR, Virani SS, Mszar R, Krumholz HM, Nasir K. Burden and Consequences of Financial Hardship From Medical Bills Among Nonelderly Adults With Diabetes Mellitus in the United States. Circulation Cardiovascular Quality And Outcomes 2020, 13: e006139. PMID: 32069093, DOI: 10.1161/circoutcomes.119.006139.
- Pandey A, Keshvani N, Khera R, Lu D, Vaduganathan M, Maddox K, Das SR, Kumbhani DJ, Goyal A, Girotra S, Chan P, Fonarow GC, Matsouaka R, Wang TY, de Lemos JA. Temporal Trends in Racial Differences in 30-Day Readmission and Mortality Rates After Acute Myocardial Infarction Among Medicare Beneficiaries. JAMA Cardiology 2020, 5: 136-145. PMID: 31913411, PMCID: PMC6990949, DOI: 10.1001/jamacardio.2019.4845.
- Ko DT, Khera R, Lau G, Qiu F, Wang Y, Austin PC, Koh M, Lin Z, Lee DS, Wijeysundera HC, Krumholz HM. Readmission and Mortality After Hospitalization for Myocardial Infarction and Heart Failure. Journal Of The American College Of Cardiology 2020, 75: 736-746. PMID: 32081282, DOI: 10.1016/j.jacc.2019.12.026.
- Khera R, Wang Y, Bernheim SM, Lin Z, Krumholz HM. Post-discharge acute care and outcomes following readmission reduction initiatives: national retrospective cohort study of Medicare beneficiaries in the United States. The BMJ 2020, 368: l6831. PMID: 31941686, PMCID: PMC7190056, DOI: 10.1136/bmj.l6831.
- Mahajan S, Valero-Elizondo J, Khera R, Desai NR, Blankstein R, Blaha MJ, Virani SS, Kash BA, Zoghbi WA, Krumholz HM, Nasir K. Variation and Disparities in Awareness of Myocardial Infarction Symptoms Among Adults in the United States. JAMA Network Open 2019, 2: e1917885. PMID: 31851350, PMCID: PMC6991230, DOI: 10.1001/jamanetworkopen.2019.17885.
- Khera R, Valero-Elizondo J, Das SR, Virani SS, Kash BA, de Lemos JA, Krumholz HM, Nasir K. Cost-Related Medication Nonadherence in Adults With Atherosclerotic Cardiovascular Disease in the United States, 2013 to 2017. Circulation 2019, 140: 2067-2075. PMID: 31760784, DOI: 10.1161/circulationaha.119.041974.
- Angraal S, Mortazavi BJ, Gupta A, Khera R, Ahmad T, Desai NR, Jacoby DL, Masoudi FA, Spertus JA, Krumholz HM. Machine Learning Prediction of Mortality and Hospitalization in Heart Failure With Preserved Ejection Fraction. JACC Heart Failure 2019, 8: 12-21. PMID: 31606361, DOI: 10.1016/j.jchf.2019.06.013.
- Mahajan S, Gu J, Lu Y, Khera R, Spatz ES, Zhang M, Sun N, Zheng X, Zhao H, Lu H, Ma ZJ, Krumholz HM. Hemodynamic Phenotypes of Hypertension Based on Cardiac Output and Systemic Vascular Resistance. The American Journal Of Medicine 2019, 133: e127-e139. PMID: 31525336, DOI: 10.1016/j.amjmed.2019.08.042.
- Miller PE, Guha A, Khera R, Chouairi F, Ahmad T, Nasir K, Addison D, Desai NR. National Trends in Healthcare-Associated Infections for Five Common Cardiovascular Conditions. The American Journal Of Cardiology 2019, 124: 1140-1148. PMID: 31371062, PMCID: PMC7883647, DOI: 10.1016/j.amjcard.2019.06.029.
- Khera R, Wang Y, Nasir K, Lin Z, Krumholz HM. Evaluation of 30-Day Hospital Readmission and Mortality Rates Using Regression-Discontinuity Framework. Journal Of The American College Of Cardiology 2019, 74: 219-234. PMID: 31296295, PMCID: PMC8669780, DOI: 10.1016/j.jacc.2019.04.060.
- Agusala V, Khera R, Cheeran D, Mody P, Reddy PP, Link MS. Diagnostic and prognostic utility of cardiac troponin in post-cardiac arrest care. Resuscitation 2019, 141: 69-72. PMID: 31201884, DOI: 10.1016/j.resuscitation.2019.06.004.
- Hong JC, Yang GK, Delarmente BA, Khera R, Price J, Faulds J, Chen JC. Cost-minimization study of the percutaneous approach to endovascular aortic aneurysm repair. Journal Of Vascular Surgery 2019, 71: 444-449. PMID: 31176637, DOI: 10.1016/j.jvs.2019.03.040.
- Mody P, Kulkarni N, Khera R, Link MS. Targeted temperature management for cardiac arrest. Progress In Cardiovascular Diseases 2019, 62: 272-278. PMID: 31078561, DOI: 10.1016/j.pcad.2019.05.007.
- Nasir K, Khera R. Financial Toxicity of Acute Cardiovascular Disease in India. JAMA Network Open 2019, 2: e193839. PMID: 31099855, DOI: 10.1001/jamanetworkopen.2019.3839.
- Khera R, Tang Y, Girotra S, Nadkarni VM, Link MS, Raymond TT, Guerguerian AM, Berg RA, Chan PS, Investigators F. Pulselessness After Initiation of Cardiopulmonary Resuscitation for Bradycardia in Hospitalized Children. Circulation 2019, 140: 370-378. PMID: 31006260, PMCID: PMC6663562, DOI: 10.1161/circulationaha.118.039048.
- DeZorzi C, Boyle B, Qazi A, Luthra K, Khera R, Chan PS, Girotra S. Administrative Billing Codes for Identifying Patients With Cardiac Arrest. Journal Of The American College Of Cardiology 2019, 73: 1598-1600. PMID: 30922482, PMCID: PMC6625314, DOI: 10.1016/j.jacc.2019.01.030.
- Angraal S, Gupta A, Khera R, Nasir K, Desai NR. Association of access to exercise opportunities and cardiovascular mortality. American Heart Journal 2019, 212: 152-156. PMID: 31051426, DOI: 10.1016/j.ahj.2019.02.010.
- Ball S, Brown TJ, Das A, Khera R, Khanna S, Gupta A. Effect of Neutropenic Diet on Infection Rates in Cancer Patients With Neutropenia. American Journal Of Clinical Oncology 2019, 42: 270-274. PMID: 30628912, DOI: 10.1097/coc.0000000000000514.
- Khera R, Tang Y, Link MS, Krumholz HM, Girotra S, Chan PS. Association Between Hospital Recognition for Resuscitation Guideline Adherence and Rates of Survival for In-Hospital Cardiac Arrest. Circulation Cardiovascular Quality And Outcomes 2019, 12: e005429. PMID: 30871337, PMCID: PMC6592630, DOI: 10.1161/circoutcomes.118.005429.
- Okunrintemi V, Khera R, Spatz ES, Salami JA, Valero-Elizondo J, Warraich HJ, Virani SS, Blankstein R, Blaha MJ, Pawlik TM, Dharmarajan K, Krumholz HM, Nasir K. Association of Income Disparities with Patient-Reported Healthcare Experience. Journal Of General Internal Medicine 2019, 34: 884-892. PMID: 30783877, PMCID: PMC6544715, DOI: 10.1007/s11606-019-04848-4.
- Valero-Elizondo J, Khera R, Saxena A, Grandhi GR, Virani SS, Butler J, Samad Z, Desai NR, Krumholz HM, Nasir K. Financial Hardship From Medical Bills Among Nonelderly U.S. Adults With Atherosclerotic Cardiovascular Disease. Journal Of The American College Of Cardiology 2019, 73: 727-732. PMID: 30765039, DOI: 10.1016/j.jacc.2018.12.004.
- Huo X, Khera R, Zhang L, Herrin J, Bai X, Wang Q, Lu Y, Nasir K, Hu S, Li J, Li X, Zheng X, Masoudi FA, Spertus JA, Krumholz HM, Jiang L. Education level and outcomes after acute myocardial infarction in China. Heart 2019, 105: 946. PMID: 30661037, PMCID: PMC6582708, DOI: 10.1136/heartjnl-2018-313752.
- Khera R, Krumholz HM. Effects of the Hospital Readmissions Reduction Program. Circulation Cardiovascular Quality And Outcomes 2018, 11: e005083. PMID: 30562071, DOI: 10.1161/circoutcomes.118.005083.
- Khera R, Pandey A, Link MS, Sulistio MS. Managing Implantable Cardioverter-Defibrillators at End-of-Life: Practical Challenges and Care Considerations. The American Journal Of The Medical Sciences 2018, 357: 143-150. PMID: 30665495, DOI: 10.1016/j.amjms.2018.11.016.
- Salami J, Saxena A, Warraich H, Khera R, Okunrintemi V, Valero-Elizondo J, Blaha M, Blankstein R, Virani S, Veledar E, Krumholz H, Nasir K. Abstract 16990: Impact of 2013 ACC/AHA Cholesterol Management Guidelines on Statins Use Among Nationally Representative Adult Populations in United States: Medical Expenditure Panel Survey (2010-2015). Circulation 2018, 138 DOI: 10.1161/circ.138.suppl_1.16990.
- Khera R, Humbert A, Leroux B, Nichol G, Kudenchuk P, Scales D, Baker A, Austin M, Newgard CD, Radecki R, Vilke GM, Sawyer KN, Sopko G, Idris AH, Wang H, Chan PS, Kurz MC. Hospital Variation in the Utilization and Implementation of Targeted Temperature Management in Out-of-Hospital Cardiac Arrest. Circulation Cardiovascular Quality And Outcomes 2018, 11: e004829. PMID: 30571336, DOI: 10.1161/circoutcomes.118.004829.
- Annapureddy A, Valero-Elizondo J, Khera R, Grandhi GR, Spatz ES, Dreyer RP, Desai NR, Krumholz HM, Nasir K. Association Between Financial Burden, Quality of Life, and Mental Health Among Those With Atherosclerotic Cardiovascular Disease in the United States. Circulation Cardiovascular Quality And Outcomes 2018, 11: e005180. PMID: 30571331, DOI: 10.1161/circoutcomes.118.005180.
- Mody P, Brown SP, Kudenchuk PJ, Chan PS, Khera R, Ayers C, Pandey A, Kern K, de Lemos JA, Link MS, Idris AH. Intraosseous versus intravenous access in patients with out-of-hospital cardiac arrest: Insights from the resuscitation outcomes consortium continuous chest compression trial. Resuscitation 2018, 134: 69-75. PMID: 30391366, DOI: 10.1016/j.resuscitation.2018.10.031.
- Khera R, CarlLee S, Blevins A, Schweizer M, Girotra S. Early coronary angiography and survival after out-of-hospital cardiac arrest: a systematic review and meta-analysis. Open Heart 2018, 5: e000809. PMID: 30402255, PMCID: PMC6203043, DOI: 10.1136/openhrt-2018-000809.
- Jain S, Khera R, Mortensen EM, Weissler JC. Readmissions of adults within three age groups following hospitalization for pneumonia: Analysis from the Nationwide Readmissions Database. PLOS ONE 2018, 13: e0203375. PMID: 30212485, PMCID: PMC6136736, DOI: 10.1371/journal.pone.0203375.
- Angraal S, Khera R, Zhou S, Wang Y, Lin Z, Dharmarajan K, Desai NR, Bernheim SM, Drye EE, Nasir K, Horwitz LI, Krumholz HM. Trends in 30-Day Readmission Rates for Medicare and Non-Medicare Patients in the Era of the Affordable Care Act. The American Journal Of Medicine 2018, 131: 1324-1331.e14. PMID: 30016636, PMCID: PMC6380174, DOI: 10.1016/j.amjmed.2018.06.013.
- Khera R, Dharmarajan K, Wang Y, Lin Z, Bernheim SM, Wang Y, Normand ST, Krumholz HM. Association of the Hospital Readmissions Reduction Program With Mortality During and After Hospitalization for Acute Myocardial Infarction, Heart Failure, and Pneumonia. JAMA Network Open 2018, 1: e182777. PMID: 30646181, PMCID: PMC6324473, DOI: 10.1001/jamanetworkopen.2018.2777.
- Rubens M, Saxena A, Ramamoorthy V, Das S, Khera R, Hong J, Armaignac D, Veledar E, Nasir K, Gidel L. Increasing Sepsis Rates in the United States: Results From National Inpatient Sample, 2005 to 2014. Journal Of Intensive Care Medicine 2018, 35: 858-868. PMID: 30175649, DOI: 10.1177/0885066618794136.
- Kumar N, Khera R, Fonarow GC, Bhatt DL. Comparison of Outcomes of Transfemoral Versus Transapical Approach for Transcatheter Aortic Valve Implantation. The American Journal Of Cardiology 2018, 122: 1520-1526. PMID: 30190074, DOI: 10.1016/j.amjcard.2018.07.025.
- Khera R, Valero-Elizondo J, Okunrintemi V, Saxena A, Das SR, de Lemos JA, Krumholz HM, Nasir K. Association of Out-of-Pocket Annual Health Expenditures With Financial Hardship in Low-Income Adults With Atherosclerotic Cardiovascular Disease in the United States. JAMA Cardiology 2018, 3: 729-738. PMID: 29971325, PMCID: PMC6143078, DOI: 10.1001/jamacardio.2018.1813.
- Angraal S, Khera R, Wang Y, Lu Y, Jean R, Dreyer RP, Geirsson A, Desai NR, Krumholz HM. Sex and Race Differences in the Utilization and Outcomes of Coronary Artery Bypass Grafting Among Medicare Beneficiaries, 1999–2014. Journal Of The American Heart Association 2018, 7: e009014. PMID: 30005557, PMCID: PMC6064835, DOI: 10.1161/jaha.118.009014.
- Khera R, Lu Y, Lu J, Saxena A, Nasir K, Jiang L, Krumholz HM. Impact of 2017 ACC/AHA guidelines on prevalence of hypertension and eligibility for antihypertensive treatment in United States and China: nationally representative cross sectional study. The BMJ 2018, 362: k2357. PMID: 29997129, PMCID: PMC6039831, DOI: 10.1136/bmj.k2357.
- Khera R, Dorsey KB, Krumholz HM. Transition to the ICD-10 in the United States: An Emerging Data Chasm. JAMA 2018, 320: 133-134. PMID: 29868861, DOI: 10.1001/jama.2018.6823.
- Khera R, Dharmarajan K, Krumholz HM. Rising Mortality in Patients With Heart Failure in the United States Facts Versus Fiction. JACC Heart Failure 2018, 6: 610-612. PMID: 29914774, DOI: 10.1016/j.jchf.2018.02.011.
- Trends in Use and Expenditures of Brand-name Atorvastatin After Introduction of Generic AtorvastatinWarraich HJ, Salami JA, Khera R, Valero-Elizondo J, Okunrintemi V, Nasir K. Trends in Use and Expenditures of Brand-name Atorvastatin After Introduction of Generic Atorvastatin. JAMA Internal Medicine 2018, 178: 719-721. PMID: 29525818, PMCID: PMC5885171, DOI: 10.1001/jamainternmed.2018.0990.
- Wang S, Khera R, Das SR, Vigen R, Wang T, Luo X, Lu R, Zhan X, Xiao G, Vongpatanasin W, Xie Y. Usefulness of a Simple Algorithm to Identify Hypertensive Patients Who Benefit from Intensive Blood Pressure Lowering. The American Journal Of Cardiology 2018, 122: 248-254. PMID: 29880288, DOI: 10.1016/j.amjcard.2018.03.361.
- Khera R, Horwitz LI, Lin Z, Krumholz HM. Publicly Reported Readmission Measures and the Hospital Readmissions Reduction Program: A False Equivalence? Annals Of Internal Medicine 2018, 168: 670-671. PMID: 29582081, PMCID: PMC8325174, DOI: 10.7326/m18-0536.
- Warraich H, Salami J, Khera R, Okunrintemi V, Nasir K. EXCESS NATIONAL US EXPENDITURES ASSOCIATED WITH LIPITOR USE AFTER INTRODUCTION OF GENERIC ATORVASTATIN: INSIGHTS FROM THE MEDICAL EXPENDITURES PANEL SURVEY, 2012-2014. Journal Of The American College Of Cardiology 2018, 71: a1764. DOI: 10.1016/s0735-1097(18)32305-2.
- Nguyen NH, Khera R, Ohno-Machado L, Sandborn WJ, Singh S. Annual Burden and Costs of Hospitalization for High-Need, High-Cost Patients With Chronic Gastrointestinal and Liver Diseases. Clinical Gastroenterology And Hepatology 2018, 16: 1284-1292.e30. PMID: 29474966, PMCID: PMC6056327, DOI: 10.1016/j.cgh.2018.02.015.
- Pandey A, Khera R, Park B, Haykowsky M, Borlaug BA, Lewis GD, Kitzman DW, Butler J, Berry JD. Relative Impairments in Hemodynamic Exercise Reserve Parameters in Heart Failure With Preserved Ejection Fraction A Study-Level Pooled Analysis. JACC Heart Failure 2018, 6: 117-126. PMID: 29413366, PMCID: PMC8135913, DOI: 10.1016/j.jchf.2017.10.014.
- Rubens M, Saxena A, Ramamoorthy V, Khera R, Hong J, Veledar E, Nasir K. Trends in Diabetes-Related Preventable Hospitalizations in the U.S., 2005–2014. Diabetes Care 2018, 41: dc171942. PMID: 29378777, DOI: 10.2337/dc17-1942.
- Khera R, Pandey A, Chandar AK, Murad MH, Prokop LJ, Neeland IJ, Berry JD, Camilleri M, Singh S. Effects of Weight-Loss Medications on Cardiometabolic Risk Profiles: A Systematic Review and Network Meta-analysis. Gastroenterology 2018, 154: 1309-1319.e7. PMID: 29305933, PMCID: PMC5880739, DOI: 10.1053/j.gastro.2017.12.024.
- Valero-Elizondo J, Hong JC, Spatz ES, Salami JA, Desai NR, Rana JS, Khera R, Virani SS, Blankstein R, Blaha MJ, Nasir K. Persistent socioeconomic disparities in cardiovascular risk factors and health in the United States: Medical Expenditure Panel Survey 2002–2013. Atherosclerosis 2017, 269: 301-305. PMID: 29254694, DOI: 10.1016/j.atherosclerosis.2017.12.014.
- Arrieta A, Hong JC, Khera R, Virani SS, Krumholz HM, Nasir K. Updated Cost-effectiveness Assessments of PCSK9 Inhibitors From the Perspectives of the Health System and Private Payers: Insights Derived From the FOURIER Trial. JAMA Cardiology 2017, 2: 1369-1374. PMID: 29049467, PMCID: PMC5814995, DOI: 10.1001/jamacardio.2017.3655.
- Khera R, Pandey A, Koshy T, Ayers C, Nallamothu BK, Das SR, Drazner MH, Jessen ME, Kirtane AJ, Gardner TJ, de Lemos JA, Bhatt DL, Kumbhani DJ. Role of Hospital Volumes in Identifying Low-Performing and High-Performing Aortic and Mitral Valve Surgical Centers in the United States. JAMA Cardiology 2017, 2: 1322-1331. PMID: 29117319, PMCID: PMC5815001, DOI: 10.1001/jamacardio.2017.4003.
- Khera R, Pandey A. The heart failure readmission quagmire: taking a deep dive to find solutions. European Journal Of Heart Failure 2017, 20: 315-316. PMID: 29193571, DOI: 10.1002/ejhf.1082.
- Khera R, Angraal S, Couch T, Welsh JW, Nallamothu BK, Girotra S, Chan PS, Krumholz HM. Adherence to Methodological Standards in Research Using the National Inpatient Sample. JAMA 2017, 318: 2011-2018. PMID: 29183077, PMCID: PMC5742631, DOI: 10.1001/jama.2017.17653.
- Khera R, Hong JC, Saxena A, Arrieta A, Virani SS, Blankstein R, de Lemos JA, Krumholz HM, Nasir K. Burden of Catastrophic Health Expenditures for Acute Myocardial Infarction and Stroke Among Uninsured in the United States. Circulation 2017, 137: 408-410. PMID: 29133601, PMCID: PMC5780190, DOI: 10.1161/circulationaha.117.030128.
- Khera R, Spertus JA, Starks MA, Tang Y, Bradley SM, Girotra S, Chan PS. Administrative Codes for Capturing In-Hospital Cardiac Arrest. JAMA Cardiology 2017, 2: 1275-1277. PMID: 28877294, PMCID: PMC5736791, DOI: 10.1001/jamacardio.2017.2904.
- Khera R, Pandey A, Ayers CR, Agusala V, Pruitt SL, Halm EA, Drazner MH, Das SR, de Lemos JA, Berry JD. Contemporary Epidemiology of Heart Failure in Fee-For-Service Medicare Beneficiaries Across Healthcare Settings. Circulation Heart Failure 2017, 10: e004402. PMID: 29129828, PMCID: PMC6057614, DOI: 10.1161/circheartfailure.117.004402.
- Kumar N, Khera R, Garg N, Echouffo-Tcheugui JB, Venkatraman A, Pandey A, Bhatt DL. Comparison of Outcomes of Transcatheter Versus Surgical Aortic Valve Replacement in Patients With Chronic Kidney Disease. The American Journal Of Cardiology 2017, 121: 343-348. PMID: 29268936, DOI: 10.1016/j.amjcard.2017.10.029.
- Cheeran D, Khan S, Khera R, Bhatt A, Garg S, Grodin JL, Morlend R, Araj FG, Amin AA, Thibodeau JT, Das S, Drazner MH, Mammen PPA. Predictors of Death in Adults With Duchenne Muscular Dystrophy–Associated Cardiomyopathy. Journal Of The American Heart Association 2017, 6: e006340. PMID: 29042427, PMCID: PMC5721845, DOI: 10.1161/jaha.117.006340.
- Khera R, Jain S, Pandey A, Agusala V, Kumbhani DJ, Das SR, Berry JD, de Lemos JA, Girotra S. Comparison of Readmission Rates After Acute Myocardial Infarction in 3 Patient Age Groups (18 to 44, 45 to 64, and ≥65 Years) in the United States. The American Journal Of Cardiology 2017, 120: 1761-1767. PMID: 28865892, PMCID: PMC5825232, DOI: 10.1016/j.amjcard.2017.07.081.
- Khera R, Krumholz HM. With Great Power Comes Great Responsibility. Circulation Cardiovascular Quality And Outcomes 2017, 10: e003846. PMID: 28705865, PMCID: PMC5728376, DOI: 10.1161/circoutcomes.117.003846.
- Khera R, Kumbhani DJ. Editorial Commentary: Deconstructing the dogma: Its time to untangle and reassess acute myocardial infarction care. Trends In Cardiovascular Medicine 2017, 27: 492-493. PMID: 28760376, DOI: 10.1016/j.tcm.2017.06.010.
- Dulai PS, Singh S, Marquez E, Khera R, Prokop LJ, Limburg PJ, Gupta S, Murad MH. Chemoprevention of colorectal cancer in individuals with previous colorectal neoplasia: systematic review and network meta-analysis. The BMJ 2016, 355: i6188. PMID: 27919915, PMCID: PMC5137632, DOI: 10.1136/bmj.i6188.
- Khera R, Chan PS, Donnino M, Girotra S. Hospital Variation in Time to Epinephrine for Nonshockable In-Hospital Cardiac Arrest. Circulation 2016, 134: 2105-2114. PMID: 27908910, PMCID: PMC5173427, DOI: 10.1161/circulationaha.116.025459.
- Khera R, Pandey A, Kumar N, Singh R, Bano S, Golwala H, Kumbhani DJ, Girotra S, Fonarow GC. Variation in Hospital Use and Outcomes Associated With Pulmonary Artery Catheterization in Heart Failure in the United States. Circulation Heart Failure 2016, 9: e003226. PMID: 27780836, PMCID: PMC5123800, DOI: 10.1161/circheartfailure.116.003226.
- Jain S, Khera R, Girotra S, Badesch D, Wang Z, Murad MH, Blevins A, Schmidt GA, Singh S, Gerke AK. Comparative Effectiveness of Pharmacologic Interventions for Pulmonary Arterial Hypertension A Systematic Review and Network Meta-Analysis. CHEST Journal 2016, 151: 90-105. PMID: 27615023, PMCID: PMC5310124, DOI: 10.1016/j.chest.2016.08.1461.
- Singh S, Khera R, Murad MH, Loomba R. Reply. Hepatology 2016, 64: 694-694. PMID: 26690078, DOI: 10.1002/hep.28412.
- Kumar N, Khera R, Garg N. Atrial fibrillation associated hospitalizations in patients with end-stage renal disease in the United States, 2003–2012. Heart Rhythm 2016, 13: 2027-2033. PMID: 27374238, DOI: 10.1016/j.hrthm.2016.06.031.
- Khera R, Murad MH, Chandar AK, Dulai PS, Wang Z, Prokop LJ, Loomba R, Camilleri M, Singh S. Association of Pharmacological Treatments for Obesity With Weight Loss and Adverse Events: A Systematic Review and Meta-analysis. JAMA 2016, 315: 2424-2434. PMID: 27299618, PMCID: PMC5617638, DOI: 10.1001/jama.2016.7602.
- Kumar N, Khera R, Pandey A, Garg N. Racial Differences in Outcomes after Acute Ischemic Stroke Hospitalization in the United States. Journal Of Stroke And Cerebrovascular Diseases 2016, 25: 1970-1977. PMID: 27212273, DOI: 10.1016/j.jstrokecerebrovasdis.2016.03.049.
- Khera R, Girotra S. Response to “the Use of Mechanical Support Devices in Percutaneous Coronary Interventions: the Controversy?”. The American Journal Of Cardiology 2016, 120: e5. PMID: 27269587, DOI: 10.1016/j.amjcard.2016.05.001.
- Khera R, Girotra S. Mechanical Circulatory Support and Rationale for Future Research—Reply. JAMA Internal Medicine 2016, 176: 714-715. PMID: 27136338, DOI: 10.1001/jamainternmed.2016.0810.
- Kumar N, Venkatraman A, Pandey A, Khera R, Garg N. Weekend hospitalizations for acute aortic dissection have a higher risk of in-hospital mortality compared to weekday hospitalizations. International Journal Of Cardiology 2016, 214: 448-450. PMID: 27093682, DOI: 10.1016/j.ijcard.2016.03.187.
- Khera R, Girotra S. Response to “Higher mortality among males in takotsubo cardiomyopathy”. American Heart Journal 2016, 176: e3. PMID: 27264234, DOI: 10.1016/j.ahj.2016.03.010.
- Pandey A, Khera R, Kumar N, Golwala H, Girotra S, Fonarow GC. Use of Pulmonary Artery Catheterization in US Patients With Heart Failure, 2001-2012. JAMA Internal Medicine 2016, 176: 1-4. PMID: 26618346, PMCID: PMC4780342, DOI: 10.1001/jamainternmed.2015.6190.
- Jain S, Khera R, Suneja M, Gehlbach B, Kuperman E, Lopez F. Role of D-dimer Assays in the Diagnostic Evaluation of Pulmonary Embolism. The American Journal Of The Medical Sciences 2015, 350: 501-507. PMID: 25719981, DOI: 10.1097/maj.0000000000000405.
- Khera R, Light-McGroary K, Zahr F, Horwitz PA, Girotra S. Trends in hospitalization for takotsubo cardiomyopathy in the United States. American Heart Journal 2015, 172: 53-63. PMID: 26856216, PMCID: PMC4748175, DOI: 10.1016/j.ahj.2015.10.022.
- Singh S, Khera R, Allen AM, Murad MH, Loomba R. Comparative effectiveness of pharmacological interventions for nonalcoholic steatohepatitis: A systematic review and network meta‐analysis. Hepatology 2015, 62: 1417-1432. PMID: 26189925, DOI: 10.1002/hep.27999.
- Khera R, Cram P, Vaughan-Sarrazin M, Horwitz PA, Girotra S. Use of Mechanical Circulatory Support in Percutaneous Coronary Intervention in the United States. The American Journal Of Cardiology 2015, 117: 10-16. PMID: 26547292, PMCID: PMC4690753, DOI: 10.1016/j.amjcard.2015.10.005.
- Steyers CM, Khera R, Bhave P. Pacemaker Dependency after Cardiac Surgery: A Systematic Review of Current Evidence. PLOS ONE 2015, 10: e0140340. PMID: 26470027, PMCID: PMC4607414, DOI: 10.1371/journal.pone.0140340.
- Jain S, Khera R. Herpes zoster ophthalmicus complicated by encephalitis. Canadian Medical Association Journal 2015, 188: cmaj.150342. PMID: 26350907, PMCID: PMC4771550, DOI: 10.1503/cmaj.150342.
- Khera R, Cram P, Girotra S. Letter by Khera et al Regarding Article, “Impact of Annual Operator and Institutional Volume on Percutaneous Coronary Intervention Outcomes. Circulation 2015, 132: e35. PMID: 26240269, PMCID: PMC4617823, DOI: 10.1161/circulationaha.114.013342.
- Thirugnanasambandam N, Khera R, Wang H, Kukke SN, Hallett M. Distinct interneuronal networks influence excitability of the surround during movement initiation. Journal Of Neurophysiology 2015, 114: 1102-1108. PMID: 26041828, PMCID: PMC4588516, DOI: 10.1152/jn.00791.2014.
- Khera R, Cram P, Lu X, Vyas A, Gerke A, Rosenthal GE, Horwitz PA, Girotra S. Trends in the Use of Percutaneous Ventricular Assist Devices: Analysis of National Inpatient Sample Data, 2007 Through 2012. JAMA Internal Medicine 2015, 175: 941-950. PMID: 25822170, PMCID: PMC4780323, DOI: 10.1001/jamainternmed.2014.7856.
- Khera R, Vaughan-Sarrazin M, Rosenthal GE, Girotra S. Racial Disparities in Outcomes After Cardiac Surgery: the Role of Hospital Quality. Current Cardiology Reports 2015, 17: 29. PMID: 25894800, PMCID: PMC4780328, DOI: 10.1007/s11886-015-0587-7.
- Jain S, Khera R, Corrales–Medina V, Townsend RR, Chirinos JA. “Inflammation and arterial stiffness in humans”. Atherosclerosis 2014, 237: 381-390. PMID: 25463062, DOI: 10.1016/j.atherosclerosis.2014.09.011.
- Khera R, Jain S, Lodha R, Ramakrishnan S. Gender bias in child care and child health: global patterns. Archives Of Disease In Childhood 2013, 99: 369. PMID: 24344176, DOI: 10.1136/archdischild-2013-303889.
- Das N, Biswas B, Khera R. Membrane-Bound Complement Regulatory Proteins as Biomarkers and Potential Therapeutic Targets for SLE. Advances In Experimental Medicine And Biology 2012, 735: 55-81. PMID: 23402019, DOI: 10.1007/978-1-4614-4118-2_4.
- Ramakrishnan S, Khera R, Jain S, Saxena A, Kailash S, Karthikeyan G, Kothari SS, Juneja R, Bhargava B, Kalaivani M, Mehta M, Bahl VK, Airan B. Gender differences in the utilisation of surgery for congenital heart disease in India. Heart 2011, 97: 1920. PMID: 21653217, DOI: 10.1136/hrt.2011.224410.
- Khera R, Jain S, Kumar L, Thulkar S, Vijayraghwan M, Dawar R. Diffuse large B-cell lymphoma: experience from a tertiary care center in north India. Medical Oncology 2009, 27: 310-318. PMID: 19350421, DOI: 10.1007/s12032-009-9211-2.
- Khera R, Das N. Complement Receptor 1: Disease associations and therapeutic implications. Molecular Immunology 2008, 46: 761-772. PMID: 19004497, PMCID: PMC7125513, DOI: 10.1016/j.molimm.2008.09.026.
Biography
Rohan Khera, MBBS (a medical degree awarded in several countries outside the U.S.), is a cardiologist who studies the use of data and artificial intelligence to determine the best therapies for patientswith heart issues.
His work explores the use of “digital phenotyping,” or data from devices like personal smartphones. The information found there—including data regarding activity, social interactions, and day-to-day behaviors—can be combined with information from patients’ electronic health records to determine treatment possibilities.
Often, physicians use a simple questionnaire to determine patient risk for cardiovascular issues. One of Dr. Khera’s studies suggests that using a patient’s electronic medical record can produce substantially more accurate predictions.
As leader of the Cardiovascular Data Science (CarDS) Lab, Dr. Khera heads a multidisciplinary group focused on data-driven learning in heart disease. Some of his work helps teams evaluate how accurately patients are diagnosed and treated. The group also designs new treatments and examines whether physicians follow what is considered best care.
Dr. Khera has published articles in leading medical journals, including The Journal of the American Medical Association, The BMJ, Circulation, andNature Communications.
Additionally, Dr. Khera has received numerous awards, including Young Investigator awards from the American College of Cardiology and the American Heart Association Resuscitation Science. The National Heart, Lung, and Blood Institute awarded Dr. Khera a career development grant to develop automated tools for better care for heart patients.
Titles
- Assistant Professor of Medicine (Cardiovascular Medicine) and of Biostatistics (Health Informatics)
- Clinical Director, Center for Health Informatics and Analytics, YNHH/Yale CORE
- Director, Cardiovascular Data Science Lab (CarDS)
Education & Training
- FellowshipUT Southwestern Medical Center (2020)
- MSUT Southwestern Medical Center (2019)
- Clinical ScholarUT Southwestern Medical Center (2019)
- ResidencyUniversity of Iowa Carver College of Medicine (2016)
- InternshipUniversity of Iowa Carver College of Medicine (2014)
- MDAll India Institute of Medical Sciences (2011)
Languages Spoken
- English
- हिन्दी (Hindi)
- ਪੰਜਾਬੀ (Punjabi)
Additional Information
- Fellow of the American College of Cardiology: American Heart Association (2024)
- Fellow of the American College of Cardiology: American College of Cardiology (2023)
- ACC Emerging Faculty Leadership Academy: American College of Cardiology (2023)
- Blavatnik Award: Blavatnik Family Fund (2023)
- Young Physician-Scientist Award: American Society for Clinical Investigation (ASCI) (2023)
- Clinical Scientist Development Award: Doris Duke Charitable Foundation (2022)
- Jeremiah Stamler Distinguished Young Investigator Research Award: (2021)
- Young Investigator Award: American College of Cardiology (2019)
- Young Investigator Award: American Heart Association Resuscitation Science (2018)
- Francois M. Abboud Internal Medicine Research Award: University of Iowa Carver College of Medicine (2015)
- AB of Preventive Medicine, Clinical Informatics (2024)
- American Heart Association (2024 - 2025): Member
- National Science Foundation (2024): NSF-NIH Smart Health and Biomedical Research in the Era of Artificial Intelligence and Advanced Data Science (SCH) | NSF - National Science Foundation
- UK Biobank (2024 - 2025): Expert
- AHA Scientific Sessions Late-Breaking Science Working Group (2024): Advisor
- American College of Cardiology (2024 - Present): Special Advisor for Artificial Intelligence
- JAMA (2023 - Present): Associate Editor
- Yale Task Force on Artificial Intelligence - YSM AI in Clinical Research Panel (2023 - 2024): Member
- Yale Task Force on Artificial Intelligence - YSM/YNHH AI in Clinical Practice Panel (2023 - 2024): Member
- Nature (2023 - Present): Reviewer
- Nature Medicine (2023 - Present): Reviewer
- Holste G, Oikonomou E, Mortazavi B, Coppi A, Faridi K, Miller E, Forrest J, McNamara R, Ohno-Machado L, Yuan N, Gupta A, Ouyang D, Krumholz H, Wang Z, Khera R. Severe aortic stenosis detection by deep learning applied to echocardiography. European Heart Journal 2023, 44: 4592-4604. PMID: 37611002, PMCID: PMC11004929, DOI: 10.1093/eurheartj/ehad456.
- Khera R, Dhingra L, Aminorroaya A, Li K, Zhou J, Arshad F, Blacketer C, Bowring M, Bu F, Cook M, Dorr D, Duarte-Salles T, DuVall S, Falconer T, French T, Hanchrow E, Horban S, Lau W, Li J, Liu Y, Lu Y, Man K, Matheny M, Mathioudakis N, McLemore M, Minty E, Morales D, Nagy P, Nishimura A, Ostropolets A, Pistillo A, Posada J, Pratt N, Reyes C, Ross J, Seager S, Shah N, Simon K, Wan E, Yang J, Yin C, You S, Schuemie M, Ryan P, Hripcsak G, Krumholz H, Suchard M. Multinational patterns of second line antihyperglycaemic drug initiation across cardiovascular risk groups: federated pharmacoepidemiological evaluation in LEGEND-T2DM. BMJ Medicine 2023, 2: e000651. PMID: 37829182, PMCID: PMC10565313, DOI: 10.1136/bmjmed-2023-000651.
- Khunte A, Sangha V, Oikonomou E, Dhingra L, Aminorroaya A, Mortazavi B, Coppi A, Brandt C, Krumholz H, Khera R. Detection of left ventricular systolic dysfunction from single-lead electrocardiography adapted for portable and wearable devices. Npj Digital Medicine 2023, 6: 124. PMID: 37433874, PMCID: PMC10336107, DOI: 10.1038/s41746-023-00869-w.
- Sangha V, Nargesi A, Dhingra L, Khunte A, Mortazavi B, Ribeiro A, Banina E, Adeola O, Garg N, Brandt C, Miller E, Ribeiro A, Velazquez E, Giatti L, Barreto S, Foppa M, Yuan N, Ouyang D, Krumholz H, Khera R. Detection of Left Ventricular Systolic Dysfunction From Electrocardiographic Images. Circulation 2023, 148: 765-777. PMID: 37489538, PMCID: PMC10982757, DOI: 10.1161/circulationaha.122.062646.
- Oikonomou EK, Spatz ES, Suchard MA, Khera R. Individualising intensive systolic blood pressure reduction in hypertension using computational trial phenomaps and machine learning: a post-hoc analysis of randomised clinical trials. The Lancet Digital Health 2022, 4: e796-e805. PMID: 36307193, PMCID: PMC9768739, DOI: 10.1016/s2589-7500(22)00170-4.
- Silva G, Khera R, Schwamm L, Acampa M, Adelman E, Boltze J, Broderick J, Brodtmann A, Christensen H, Dalli L, Duncan K, Elgendy I, Ergul A, Goldstein L, Hinkle J, Johansen M, Jood K, Kasner S, Levine S, Li Z, Lip G, Marsh E, Muir K, Ospel J, Pera J, Quinn T, Räty S, Ranta A, Richards L, Romero J, Willey J, Hillis A, Veerbeek J. Reviewer Experience Detecting and Judging Human Versus Artificial Intelligence Content: The Stroke Journal Essay Contest. Stroke 2024 PMID: 39224979, DOI: 10.1161/strokeaha.124.045012.
- Oikonomou E, Sangha V, Dhingra L, Aminorroaya A, Coppi A, Krumholz H, Baldassarre L, Khera R. Artificial Intelligence-Enhanced Risk Stratification of Cancer Therapeutics-Related Cardiac Dysfunction Using Electrocardiographic Images. Circulation Cardiovascular Quality And Outcomes 2024 PMID: 39221857, DOI: 10.1161/circoutcomes.124.011504.
- Khera R, Aminorroaya A, Dhingra L, Thangaraj P, Pedroso Camargos A, Bu F, Ding X, Nishimura A, Anand T, Arshad F, Blacketer C, Chai Y, Chattopadhyay S, Cook M, Dorr D, Duarte-Salles T, DuVall S, Falconer T, French T, Hanchrow E, Kaur G, Lau W, Li J, Li K, Liu Y, Lu Y, Man K, Matheny M, Mathioudakis N, McLeggon J, McLemore M, Minty E, Morales D, Nagy P, Ostropolets A, Pistillo A, Phan T, Pratt N, Reyes C, Richter L, Ross J, Ruan E, Seager S, Simon K, Viernes B, Yang J, Yin C, You S, Zhou J, Ryan P, Schuemie M, Krumholz H, Hripcsak G, Suchard M. Comparative Effectiveness of Second-Line Antihyperglycemic Agents for Cardiovascular Outcomes A Multinational, Federated Analysis of LEGEND-T2DM. Journal Of The American College Of Cardiology 2024, 84: 904-917. PMID: 39197980, DOI: 10.1016/j.jacc.2024.05.069.
- Jiang J, Thi Vy H, Charney A, Kovatch P, Reddy V, Jayaraman P, Do R, Khera R, Chugh S, Bhatt D, Vaid A, Lampert J, Nadkarni G. Multimodal fusion learning for long QT syndrome pathogenic genotypes in a racially diverse population. Npj Digital Medicine 2024, 7: 226. PMID: 39181999, PMCID: PMC11344778, DOI: 10.1038/s41746-024-01218-1.
- Zhou T, Sawano M, Arun A, Caraballo C, Michelsen T, McAlpine L, Bhattacharjee B, Lu Y, Khera R, Huang C, Warner F, Herrin J, Iwasaki A, Krumholz H. Internal tremors and vibrations in long COVID: a cross-sectional study. The American Journal Of Medicine 2024 PMID: 39069199, DOI: 10.1016/j.amjmed.2024.07.008.
- Khera R. AI-enabled diagnosis from an electrocardiogram image: the next frontier of innovation in a century-old technology. Heart 2024, 110: heartjnl-2024-324299. PMID: 39048290, PMCID: PMC11328242, DOI: 10.1136/heartjnl-2024-324299.
- Khera R, Aminorroaya A, Kennedy K, Chan P, Investigators A, Grossestreuer A, Moskowitz A, Ornato J, Churpek M, Starks M, Girotra S, Perman S. Correlation between hospital rates of survival to discharge and long-term survival for in-hospital cardiac arrest: Insights from Get With The Guidelines®-Resuscitation registry. Resuscitation 2024, 202: 110322. PMID: 39029583, PMCID: PMC11390317, DOI: 10.1016/j.resuscitation.2024.110322.
- Oikonomou E, Khera R. Designing medical artificial intelligence systems for global use: focus on interoperability, scalability, and accessibility. Hellenic Journal Of Cardiology 2024 PMID: 39025234, DOI: 10.1016/j.hjc.2024.07.003.
- Shimbo D, Shah R, Abdalla M, Agarwal R, Ahmad F, Anaya G, Attia Z, Bull S, Chang A, Commodore-Mensah Y, Ferdinand K, Kawamoto K, Khera R, Leopold J, Luo J, Makhni S, Mortazavi B, Oh Y, Savage L, Spatz E, Stergiou G, Turakhia M, Whelton P, Yancy C, Iturriaga E. Transforming Hypertension Diagnosis and Management in The Era of Artificial Intelligence: A 2023 National Heart, Lung, and Blood Institute (NHLBI) Workshop Report. Hypertension 2024 PMID: 39011653, DOI: 10.1161/hypertensionaha.124.22095.
- Oikonomou E, Khera R. Artificial intelligence-enhanced patient evaluation: bridging art and science. European Heart Journal 2024, 45: 3204-3218. PMID: 38976371, PMCID: PMC11400875, DOI: 10.1093/eurheartj/ehae415.
- Holste G, Oikonomou E, Mortazavi B, Wang Z, Khera R. Efficient deep learning-based automated diagnosis from echocardiography with contrastive self-supervised learning. Communications Medicine 2024, 4: 133. PMID: 38971887, PMCID: PMC11227494, DOI: 10.1038/s43856-024-00538-3.
- Khera R, Oikonomou E, Nadkarni G, Morley J, Wiens J, Butte A, Topol E. Transforming Cardiovascular Care With Artificial Intelligence: From Discovery to Practice JACC State-of-the-Art Review. Journal Of The American College Of Cardiology 2024, 84: 97-114. PMID: 38925729, DOI: 10.1016/j.jacc.2024.05.003.
- Arun A, Sawano M, Lu Y, Warner F, Caraballo C, Khera R, Echols M, Yancy C, Krumholz H. Excess Cardiovascular Mortality Among Black Americans 2000-2022. Journal Of The American College Of Cardiology 2024, 84: 581-588. PMID: 38901531, DOI: 10.1016/j.jacc.2024.06.004.
- Camargos A, Barreto S, Brant L, Ribeiro A, Dhingra L, Aminorroaya A, Bittencourt M, Figueiredo R, Khera R. Performance of contemporary cardiovascular risk stratification scores in Brazil: an evaluation in the ELSA-Brasil study. Open Heart 2024, 11: e002762. PMID: 38862252, PMCID: PMC11168182, DOI: 10.1136/openhrt-2024-002762.
- Oikonomou E, Holste G, Yuan N, Coppi A, McNamara R, Haynes N, Vora A, Velazquez E, Li F, Menon V, Kapadia S, Gill T, Nadkarni G, Krumholz H, Wang Z, Ouyang D, Khera R. A Multimodal Video-Based AI Biomarker for Aortic Stenosis Development and Progression. JAMA Cardiology 2024, 9: 534-544. PMID: 38581644, PMCID: PMC10999005, DOI: 10.1001/jamacardio.2024.0595.
- L’Italien G, Oikonomou E, Khera R, Potashman M, Beiner M, Maclaine G, Schmahmann J, Perlman S, Coric V. Video-Based Kinematic Analysis of Movement Quality in a Phase 3 Clinical Trial of Troriluzole in Adults with Spinocerebellar Ataxia: A Post Hoc Analysis. Neurology And Therapy 2024, 13: 1287-1301. PMID: 38814532, PMCID: PMC11263303, DOI: 10.1007/s40120-024-00625-6.
- Krumholz H, Sawano M, Bhattacharjee B, Caraballo C, Khera R, Li S, Herrin J, Coppi A, Holub J, Henriquez Y, Johnson M, Goddard T, Rocco E, Hummel A, Al Mouslmani M, Putrino D, Carr K, Carvajal-Gonzalez S, Charnas L, De Jesus M, Ziegler F, Iwasaki A. The PAX LC Trial: A Decentralized, Phase 2, Randomized, Double-blind Study of Nirmatrelvir/Ritonavir Compared with Placebo/Ritonavir for Long COVID. The American Journal Of Medicine 2024 PMID: 38735354, DOI: 10.1016/j.amjmed.2024.04.030.
- Aminorroaya A, Dhingra L, Oikonomou E, Saadatagah S, Thangaraj P, Vasisht Shankar S, Spatz E, Khera R. Development and multinational validation of an algorithmic strategy for high Lp(a) screening. Nature Cardiovascular Research 2024, 3: 558-566. PMID: 39195936, DOI: 10.1038/s44161-024-00469-1.
- Bibbins-Domingo K, Angus D, Park H, Lewis R, Khera R, Zeis J, Flanagin A, Curfman G. Introducing the JAMA Summit. JAMA 2024, 331: 1451-1451. DOI: 10.1001/jama.2024.5570.
- Vaid A, Duong S, Lampert J, Kovatch P, Freeman R, Argulian E, Croft L, Lerakis S, Goldman M, Khera R, Nadkarni G. Local large language models for privacy-preserving accelerated review of historic echocardiogram reports. Journal Of The American Medical Informatics Association 2024, 31: 2097-2102. PMID: 38687616, PMCID: PMC11339495, DOI: 10.1093/jamia/ocae085.
- Gonzalez P, Hebbe A, Hussain Y, Khera R, Banerjee S, Plomondon M, Waldo S, Pfau S, Curtis J, Shah S. Real-World Experience and Outcomes With Percutaneous Coronary Intervention for Protected Versus Unprotected Left Main Coronary Artery Disease: Insights from the Veteran Affairs Clinical Assessment Reporting and Tracking Program. The American Journal Of Cardiology 2024, 222: 39-50. PMID: 38677666, DOI: 10.1016/j.amjcard.2024.04.039.
- Beiner M, Oikonomou E, L’Italien G, Khera R, Potashman M, Schmahmann J, Perlman S, Coric V. Automated Video-based Characterization of Movement Quality in a Phase III Clinical Trial of Troriluzole in Subjects with Spinocerebellar Ataxia (P6-3.014). Neurology 2024, 102 DOI: 10.1212/wnl.0000000000205170.
- Oikonomou E, Aminorroaya A, Dhingra L, Partridge C, Velazquez E, Desai N, Krumholz H, Miller E, Khera R. Real-world evaluation of an algorithmic machine-learning-guided testing approach in stable chest pain: a multinational, multicohort study. European Heart Journal - Digital Health 2024, 5: 303-313. PMID: 38774380, PMCID: PMC11104476, DOI: 10.1093/ehjdh/ztae023.
- Jain S, Elias P, Poterucha T, Randazzo M, Lopez Jimenez F, Khera R, Perez M, Ouyang D, Pirruccello J, Salerno M, Einstein A, Avram R, Tison G, Nadkarni G, Natarajan V, Pierson E, Beecy A, Kumaraiah D, Haggerty C, Avari Silva J, Maddox T. Artificial Intelligence in Cardiovascular Care—Part 2: Applications JACC Review Topic of the Week. Journal Of The American College Of Cardiology 2024, 83: 2487-2496. PMID: 38593945, DOI: 10.1016/j.jacc.2024.03.401.
- Elias P, Jain S, Poterucha T, Randazzo M, Lopez Jimenez F, Khera R, Perez M, Ouyang D, Pirruccello J, Salerno M, Einstein A, Avram R, Tison G, Nadkarni G, Natarajan V, Pierson E, Beecy A, Kumaraiah D, Haggerty C, Avari Silva J, Maddox T. Artificial Intelligence for Cardiovascular Care—Part 1: Advances JACC Review Topic of the Week. Journal Of The American College Of Cardiology 2024, 83: 2472-2486. PMID: 38593946, DOI: 10.1016/j.jacc.2024.03.400.
- Saha A, Li S, de Lemos J, Pandey A, Bhatt D, Fonarow G, Nallamothu B, Wang T, Navar A, Peterson E, Matsouaka R, Bavry A, Das S, Grodin J, Khera R, Drazner M, Kumbhani D, Registry N. Characteristics of High-Performing Hospitals in Cardiogenic Shock Following Acute Myocardial Infarction. The American Journal Of Cardiology 2024, 221: 19-28. PMID: 38583700, DOI: 10.1016/j.amjcard.2024.04.002.
- Flanagin A, Pirracchio R, Khera R, Berkwits M, Hswen Y, Bibbins-Domingo K. Reporting Use of AI in Research and Scholarly Publication—JAMA Network Guidance. JAMA 2024, 331: 1096-1098. PMID: 38451540, DOI: 10.1001/jama.2024.3471.
- Aminorroaya A, Chan P, Kennedy K, Khera R. CORRELATION BETWEEN HOSPITAL RATES OF SURVIVAL TO DISCHARGE AND LONG-TERM SURVIVAL FOR IN-HOSPITAL CARDIAC ARREST: INSIGHTS FROM GET WITH THE GUIDELINES®RESUSCITATION. Journal Of The American College Of Cardiology 2024, 83: 2557. DOI: 10.1016/s0735-1097(24)04547-9.
- Dhingra L, Aminorroaya A, Oikonomou E, Sangha V, Khunte A, Khera R. A WEARABLE-ADAPTED ARTIFICIAL INTELLIGENCE ALGORITHM FOR HEART FAILURE PREDICTION FROM SINGLE-LEAD ELECTROCARDIOGRAMS IN A LARGE NATIONWIDE COHORT STUDY. Journal Of The American College Of Cardiology 2024, 83: 2341. DOI: 10.1016/s0735-1097(24)04331-6.
- Ahmed A, Agarwal R, Khera R, Liu Y, Sinusas A, Miller E, Feher A. A COMPARATIVE ANALYSIS OF PET, CZT SPECT, AND CONVENTIONAL SPECT IN MODERN CARDIOLOGY. Journal Of The American College Of Cardiology 2024, 83: 1365. DOI: 10.1016/s0735-1097(24)03355-2.
- Khaloo P, Wheelock K, Kapadia S, Khera R. TEMPORAL TRENDS IN ACCESS TO CARDIAC ELECTROPHYSIOLOGICAL CARE IN UNITED STATES: INSIGHT FROM US MEDICARE PHYSICIAN CLAIMS DATABASE (2013-2020). Journal Of The American College Of Cardiology 2024, 83: 29. DOI: 10.1016/s0735-1097(24)02019-9.
- Oikonomou E, Holste G, Nadkarni G, Wang Z, Khera R. CROSS-MODAL VALIDATION OF AN ARTIFICIAL INTELLIGENCE VIDEO-BASED APPROACH FOR THE AUTOMATED RISK STRATIFICATION OF AORTIC STENOSIS. Journal Of The American College Of Cardiology 2024, 83: 1418. DOI: 10.1016/s0735-1097(24)03408-9.
- Thangaraj P, Shankar S, Oikonomou E, Khera R. EVIDENCE FROM RANDOMIZED CONTROLLED TRIAL TO REAL-WORLD PATIENTS USING ELECTRONIC HEALTH RECORD-ADAPTED DIGITAL TWINS: A NOVEL APPLICATION OF GENERATIVE ARTIFICIAL INTELLIGENCE. Journal Of The American College Of Cardiology 2024, 83: 2340. DOI: 10.1016/s0735-1097(24)04330-4.
- Sangha V, Dhingra L, Aminorroaya A, Khera R. USING PHOTOS OF ELECTROCARDIOGRAMS AS A BIOMARKER FOR CARDIOVASCULAR RISK - A MULTINATIONAL ASSESSMENT OF A NOVEL ARTIFICIAL INTELLIGENCE APPROACH. Journal Of The American College Of Cardiology 2024, 83: 2443. DOI: 10.1016/s0735-1097(24)04433-4.
- Adejumo P, Dhingra L, Aminorroaya A, Khera R. A NOVEL DEEP LEARNING APPROACH FOR AUTOMATED EXTRACTION OF FUNCTIONAL STATUS AND NEW YORK HEART ASSOCIATION CLASS FOR HEART FAILURE PATIENTS DURING OUTPATIENT ENCOUNTERS. Journal Of The American College Of Cardiology 2024, 83: 313. DOI: 10.1016/s0735-1097(24)02303-9.
- Oikonomou E, Aminorroaya A, Dhingra L, Khera R. MULTINATIONAL REAL-WORLD EVALUATION OF A MACHINE LEARNING-DERIVED TOOL FOR ANATOMICAL VERSUS FUNCTIONAL TESTING IN SUSPECTED CORONARY ARTERY DISEASE. Journal Of The American College Of Cardiology 2024, 83: 1357. DOI: 10.1016/s0735-1097(24)03347-3.
- Dhingra L, Sangha V, Aminorroaya A, Camargos A, Oikonomou E, Khera R. HEART FAILURE RISK PREDICTION USING ARTIFICIAL INTELLIGENCE ON ECG PHOTOS IN LARGE CONTEMPORARY COHORT. Journal Of The American College Of Cardiology 2024, 83: 277. DOI: 10.1016/s0735-1097(24)02267-8.
- Feliciano K, Aminorroaya A, Dhingra L, Thangaraj P, Adejumo P, Khera R. WEARABLE DEVICE USE PATTERNS AMONG THOSE WITH CARDIOVASCULAR RISK IN ALL OF US RESEARCH PROGRAM: AN EVALUATION AGAINST A NATIONALLY REPRESENTATIVE DATABASE. Journal Of The American College Of Cardiology 2024, 83: 2045. DOI: 10.1016/s0735-1097(24)04035-x.
- Bansal B, Aminorroaya A, Dhingra L, Oikonomou E, Khera R. TRENDS IN KNOWLEDGE OF RISK FACTOR TARGETS AMONG PATIENTS WITH DIABETES MELLITUS IN THE UNITED STATES: A NATIONALLY REPRESENTATIVE STUDY. Journal Of The American College Of Cardiology 2024, 83: 1882. DOI: 10.1016/s0735-1097(24)03872-5.
- Khera R, Aminorroaya A, Dhingra L, Bu F, Camargos A, Falconer T, Zhou J, Dorr D, French T, Lau W, Lu Y, Blacketer C, Reyes C, Minty E, Li K, Man K, Ostropolets A, Nishimura A, Matheny M, Yang J, Ryan P, Y.F. W, Krumholz H, Hripcsak G, Suchard M. COMPARATIVE CARDIOVASCULAR EFFECTIVENESS OF ANTI-HYPERGLYCEMIC AGENTS INITIATED AS SECOND-LINE THERAPY IN TYPE 2 DIABETES: A LARGE-SCALE, MULTINATIONAL, FEDERATED TARGET TRIAL EMULATION IN THE LEGEND-T2DM STUDY. Journal Of The American College Of Cardiology 2024, 83: 1977. DOI: 10.1016/s0735-1097(24)03967-6.
- Sawano M, Khosla P, Arun A, Kaleem S, AL Mouslmani M, Caraballo C, Lu Y, Herrin J, Murugiah K, Khera R, Taylor H, Watson K, Yancy C, Krumholz H. EXCESS ISCHEMIC HEART DISEASE MORTALITY AND YEARS OF POTENTIAL LIFE LOST AMONG THE BLACK POPULATION: A TWO-DECADE ANALYSIS INCLUDING THE COVID-19 PANDEMIC. Journal Of The American College Of Cardiology 2024, 83: 1193. DOI: 10.1016/s0735-1097(24)03183-8.
- Lu Y, Arun A, Khosla P, Kaleem S, Sawano M, Herrin J, Caraballo C, Murugiah K, Khera R, Watson K, Taylor H, AL Mouslmani M, Krumholz H. HYPERTENSION EXCESS MORTALITY AND YEARS OF POTENTIAL LIFE LOST IN BLACK AMERICANS: A TWO-DECADE ANALYSIS INCLUDING THE COVID-19 PANDEMIC. Journal Of The American College Of Cardiology 2024, 83: 1675. DOI: 10.1016/s0735-1097(24)03665-9.
- Khera R. Artificial intelligence-enhanced exposomics: novel insights into cardiovascular health. European Heart Journal 2024, 45: 1550-1552. PMID: 38544282, DOI: 10.1093/eurheartj/ehae159.
- Khera R, Wiens J. Summertime for Cardiovascular AI. Circulation Cardiovascular Quality And Outcomes 2024, 17: e010404. PMID: 38502717, PMCID: PMC11117444, DOI: 10.1161/circoutcomes.123.010404.
- Oikonomou E, Khera R. Leveraging the Full Potential of Wearable Devices in Cardiomyopathies. Journal Of Cardiac Failure 2024, 30: 964-966. PMID: 38452997, DOI: 10.1016/j.cardfail.2024.02.011.
- Sangha V, Khunte A, Holste G, Mortazavi B, Wang Z, Oikonomou E, Khera R. Biometric contrastive learning for data-efficient deep learning from electrocardiographic images. Journal Of The American Medical Informatics Association 2024, 31: 855-865. PMID: 38269618, PMCID: PMC10990541, DOI: 10.1093/jamia/ocae002.
- Duong S, Vaid A, My V, Butler L, Lampert J, Pass R, Charney A, Narula J, Khera R, Sakhuja A, Greenspan H, Gelb B, Do R, Nadkarni G. Quantitative Prediction of Right Ventricular Size and Function From the ECG. Journal Of The American Heart Association 2023, 13: e031671. PMID: 38156471, PMCID: PMC10863807, DOI: 10.1161/jaha.123.031671.
- Khera R, Simon M, Ross J. Automation Bias and Assistive AI. JAMA 2023, 330: 2255-2257. PMID: 38112824, DOI: 10.1001/jama.2023.22557.
- Oikonomou E, Thangaraj P, Bhatt D, Ross J, Young L, Krumholz H, Suchard M, Khera R. An explainable machine learning-based phenomapping strategy for adaptive predictive enrichment in randomized clinical trials. Npj Digital Medicine 2023, 6: 217. PMID: 38001154, PMCID: PMC10673945, DOI: 10.1038/s41746-023-00963-z.
- Lu Y, Liu Y, Jastreboff A, Khera R, Ndumele C, Rodriguez F, Watson K, Krumholz H. Eligibility for Cardiovascular Risk Reduction Therapy in the United States Based on SELECT Trial Criteria: Insights From the National Health and Nutrition Examination Survey. Circulation Cardiovascular Quality And Outcomes 2023, 17: e010640. PMID: 37950677, PMCID: PMC10782930, DOI: 10.1161/circoutcomes.123.010640.
- Oikonomou E, Holste G, Mcnamara R, Velazquez E, Nadkarni G, Ouyang D, Krumholz H, Wang Z, Khera R. Predicting aortic stenosis progression using a video-based deep learning model of aortic stenosis built for single-view two-dimensional echocardiography. European Heart Journal 2023, 44: ehad655.040. DOI: 10.1093/eurheartj/ehad655.040.
- Sud M, Sivaswamy A, Austin P, Abdel-Qadir H, Anderson T, Khera R, Naimark D, Lee D, Roifman I, Thanassoulis G, Tu K, Wijeysundera H, Ko D. Validation of the European SCORE2 models in a Canadian primary care cohort. European Journal Of Preventive Cardiology 2023, 31: 668-676. PMID: 37946603, PMCID: PMC11025037, DOI: 10.1093/eurjpc/zwad352.
- Khaloo P, Wheelock K, Kapadia S, Khera R. Abstract 15725: Access to Pacemaker Implantation Amongst Medicare Beneficiaries: Travel Distance and Time to Nearest Clinician. Circulation 2023, 148: a15725-a15725. DOI: 10.1161/circ.148.suppl_1.15725.
- Nabi W, Aminorroaya A, Dhingra L, Khera R. Abstract 15485: Nationally Representative Trends of Overall Physical Activity and Its Subtypes Among US Adults With Diabetes, Hypertension, and Dyslipidemia: Findings From NHANES 2007-2020. Circulation 2023, 148: a15485-a15485. DOI: 10.1161/circ.148.suppl_1.15485.
- Pedroso A, Barreto S, Brant L, Ribeiro A, Bittencourt M, Figueiredo R, Khera R. Abstract 14328: Performance of Current Cardiovascular Risk Scores Among the Brazilian Population: Findings From the ELSA-Brasil Study. Circulation 2023, 148: a14328-a14328. DOI: 10.1161/circ.148.suppl_1.14328.
- Khunte A, Sangha V, Holste G, Dhingra L, Aminorroaya A, Wang Z, Khera R. Abstract 18776: ECG-GPT: Automated Complete Diagnosis Generation From ECG Images Using Novel Vision-Text Transformer Model. Circulation 2023, 148: a18776-a18776. DOI: 10.1161/circ.148.suppl_1.18776.
- Sangha V, Khunte A, Dhingra L, Oikonomou E, Khera R. Abstract 19045: Detection of Left Ventricular Systolic Dysfunction From PDF Outputs of ECGs Obtained on Wearable Devices. Circulation 2023, 148: a19045-a19045. DOI: 10.1161/circ.148.suppl_1.19045.
- Aminorroaya A, Dhingra L, Saadatagah S, Spatz E, Oikonomou E, Khera R. Abstract 17074: Development and Multinational Validation of a Machine Learning-Based Optimization for Efficient Screening for Elevated Lipoprotein(a). Circulation 2023, 148: a17074-a17074. DOI: 10.1161/circ.148.suppl_1.17074.
- Sangha V, Khunte A, Dhingra L, Oikonomou E, Khera R. Abstract 19135: Deep Learning Model for Detection of Conduction Disorders and Arrhythmias From PDF Outputs of Commercially Available Wearable Devices. Circulation 2023, 148: a19135-a19135. DOI: 10.1161/circ.148.suppl_1.19135.
- Khunte A, Aminorroaya A, Dhingra L, Sangha V, Oikonomou E, Sen S, Krumholz H, Kramer C, Desai M, Khera R. Abstract 17128: Detection of Hypertrophic Cardiomyopathy From Noisy Single-Lead Electrocardiography. Circulation 2023, 148: a17128-a17128. DOI: 10.1161/circ.148.suppl_1.17128.
- Kapadia S, Shen M, Hanna J, Wheelock K, Dhingra L, Khera R. Abstract 15414: Driving Distances and Durations to Nearest Transcatheter Aortic Valve Replacement Center for Medicare Beneficiaries Across Continental United States. Circulation 2023, 148: a15414-a15414. DOI: 10.1161/circ.148.suppl_1.15414.
- Dhingra L, Aminorroaya A, Oikonomou E, Sangha V, Krumholz H, Khera R. Abstract 17106: Comparing Pre- and Post- Pandemic Personal Health Monitoring Using Wearable Devices in United States Adults With or at Risk for Cardiovascular Disease: A Nationally Representative Study. Circulation 2023, 148: a17106-a17106. DOI: 10.1161/circ.148.suppl_1.17106.
- Aminorroaya A, Khunte A, Dhingra L, Sangha V, Sen S, Haynes N, Krumholz H, Khera R. Abstract 17098: Detection of Multiple Structural Heart Diseases Using a Novel Artificial Intelligence-Driven Algorithm for Noisy Real-World Single-Lead ECGs. Circulation 2023, 148: a17098-a17098. DOI: 10.1161/circ.148.suppl_1.17098.
- Dhingra L, Aminorroaya A, Khunte A, Sangha V, Sen S, Haynes N, Krumholz H, Khera R. Abstract 17094: An Ensemble Deep Learning Model to Automate Screening For Multiple Structural Heart Diseases on 12-Lead Electrocardiograms. Circulation 2023, 148: a17094-a17094. DOI: 10.1161/circ.148.suppl_1.17094.
- Dhingra L, Aminorroaya A, Khunte A, Sangha V, Oikonomou E, Sen S, Krumholz H, Kramer C, Desai M, Khera R. Abstract 17073: Evaluation of Impact of Septal Reduction Therapy on Deep Learning-Based Electrocardiographic Markers Hypertrophic Cardiomyopathy. Circulation 2023, 148: a17073-a17073. DOI: 10.1161/circ.148.suppl_1.17073.
- Nargesi A, Adejumo P, Rosand B, Dhingra L, Hengartner A, Sen S, Ahmad T, Ahmad F, Krumholz H, Khera R. Abstract 16207: Deep Learning-Based Natural Language Processing of Discharge Summaries for Automated Identification of Heart Failure With Reduced Ejection Fraction. Circulation 2023, 148: a16207-a16207. DOI: 10.1161/circ.148.suppl_1.16207.
- Oikonomou E, Thangaraj P, Bhatt D, Ross J, Young L, Krumholz H, Suchard M, Khera R. Abstract 15639: An Explainable Machine Learning-Based Phenomapping Strategy for Adaptive Predictive Enrichment in Randomized Controlled Trials of Preventive Interventions. Circulation 2023, 148: a15639-a15639. DOI: 10.1161/circ.148.suppl_1.15639.
- Sud M, Sivaswamy A, Austin P, Abdel-Qadir H, Anderson T, Khera R, Naimark D, Lee D, Roifman I, Thanassoulis G, Tu K, Wijeysundera H, Ko D. VALIDATION OF THE EUROPEAN SCORE2 MODELS IN A CANADIAN PRIMARY CARE COHORT. Canadian Journal Of Diabetes 2023, 47: s206. DOI: 10.1016/j.jcjd.2023.10.385.
- Thangaraj P, Khera R. Accelerating chest pain evaluation with machine learning. European Heart Journal Acute Cardiovascular Care 2023, 12: 753-754. PMID: 37793075, PMCID: PMC11004857, DOI: 10.1093/ehjacc/zuad117.
- Sud M, Sivaswamy A, Austin P, Abdel-Qadir H, Anderson T, Khera R, Naimark D, Lee D, Roifman I, Thanassoulis G, Tu K, Wijeysundera H, Ko D. VALIDATION OF THE EUROPEAN SCORE2 MODELS IN A CANADIAN PRIMARY CARE COHORT. Canadian Journal Of Cardiology 2023, 39: s248. DOI: 10.1016/j.cjca.2023.06.382.
- Oikonomou E, Khera R. Machine learning in precision diabetes care and cardiovascular risk prediction. Cardiovascular Diabetology 2023, 22: 259. PMID: 37749579, PMCID: PMC10521578, DOI: 10.1186/s12933-023-01985-3.
- Sandhu A, Khera R. Lifting the Veil on Advanced Heart Failure ∗. JACC Heart Failure 2023, 11: 1607-1610. PMID: 37737760, PMCID: PMC11009373, DOI: 10.1016/j.jchf.2023.07.031.
- Khera R, Butte A, Berkwits M, Hswen Y, Flanagin A, Park H, Curfman G, Bibbins-Domingo K. AI in Medicine—JAMA’s Focus on Clinical Outcomes, Patient-Centered Care, Quality, and Equity. JAMA 2023, 330: 818-820. PMID: 37566406, DOI: 10.1001/jama.2023.15481.
- Aminorroaya A, Dhingra L, Nargesi A, Oikonomou E, Krumholz H, Khera R. Use of Smart Devices to Track Cardiovascular Health Goals in the United States. JACC Advances 2023, 2: 100544. PMID: 38094515, PMCID: PMC10718569, DOI: 10.1016/j.jacadv.2023.100544.
- Dhingra L, Shen M, Mangla A, Khera R. Cardiovascular Care Innovation through Data-Driven Discoveries in the Electronic Health Record. The American Journal Of Cardiology 2023, 203: 136-148. PMID: 37499593, PMCID: PMC10865722, DOI: 10.1016/j.amjcard.2023.06.104.
- Zhang L, Khera R, Mortazavi B. Clinical Risk Prediction Models with Meta-Learning Prototypes of Patient Heterogeneity. Annual International Conference Of The IEEE Engineering In Medicine And Biology Society (EMBC) 2023, 00: 1-4. PMID: 38083199, PMCID: PMC11007255, DOI: 10.1109/embc40787.2023.10340765.
- See C, Wheelock K, Caraballo C, Khera R, Annapureddy A, Mahajan S, Lu Y, Krumholz H, Murugiah K. Patterns of Digoxin Prescribing for Medicare Beneficiaries in the United States 2013-2019. American Journal Of Medicine Open 2023, 10: 100048. PMID: 38213879, PMCID: PMC10783702, DOI: 10.1016/j.ajmo.2023.100048.
- Dhingra L, Aminorroaya A, Oikonomou E, Nargesi A, Wilson F, Krumholz H, Khera R. Use of Wearable Devices in Individuals With or at Risk for Cardiovascular Disease in the US, 2019 to 2020. JAMA Network Open 2023, 6: e2316634. PMID: 37285157, PMCID: PMC10248745, DOI: 10.1001/jamanetworkopen.2023.16634.
- Bejjani A, Khairani C, Lo Y, Jimenez D, Barco S, Mahajan S, Caraballo C, Klok E, Secemsky E, Aghayev A, Hunsaker A, Hussain M, Appah-Sampong A, Khera R, Goldhaber S, Zhou L, Monreal M, Krumholz H, Piazza G, Bikdeli B. Abstract 379: The Accuracy Of ICD-10 Discharge Diagnosis Codes For Identification Of Isolated Sub-Segmental Pulmonary Embolism: A PE-EHR+ Substudy. Arteriosclerosis Thrombosis And Vascular Biology 2023, 43 DOI: 10.1161/atvb.43.suppl_1.379.
- Sawano M, Lu Y, Caraballo C, Mahajan S, Dreyer R, Lichtman J, D'Onofrio G, Spatz E, Khera R, Onuma O, Murugiah K, Spertus J, Krumholz H. Sex Difference in Outcomes of Acute Myocardial Infarction in Young Patients. Journal Of The American College Of Cardiology 2023, 81: 1797-1806. PMID: 37137590, DOI: 10.1016/j.jacc.2023.03.383.
- Demkowicz P, Dhruva S, Spatz E, Beatty A, Ross J, Khera R. Physician responses to apple watch-detected irregular rhythm alerts. American Heart Journal 2023, 262: 29-37. PMID: 37084933, PMCID: PMC10988207, DOI: 10.1016/j.ahj.2023.04.008.
- Nargesi A, Clark C, Aminorroaya A, Chen L, Liu M, Reddy A, Amodeo S, Oikonomou E, Suchard M, McGuire D, Lin Z, Inzucchi S, Khera R. Persistence on Novel Cardioprotective Antihyperglycemic Therapies in the United States. The American Journal Of Cardiology 2023, 196: 89-98. PMID: 37012183, PMCID: PMC11007258, DOI: 10.1016/j.amjcard.2023.03.002.
- Bikdeli B, Lo Y, Khairani C, Bejjani A, Jimenez D, Barco S, Mahajan S, Caraballo C, Secemsky E, Klok F, Hunsaker A, Aghayev A, Muriel A, Wang Y, Hussain M, Appah-Sampong A, Lu Y, Lin Z, Aneja S, Khera R, Goldhaber S, Zhou L, Monreal M, Krumholz H, Piazza G. Developing Validated Tools to Identify Pulmonary Embolism in Electronic Databases: Rationale and Design of the PE-EHR+ Study. Thrombosis And Haemostasis 2023, 123: 649-662. PMID: 36809777, PMCID: PMC11200175, DOI: 10.1055/a-2039-3222.
- Khera R, Kondamudi N, Liu M, Ayers C, Spatz E, Rao S, Essien U, Powell-Wiley T, Nasir K, Das S, Capers Q, Pandey A. Lifetime healthcare expenses across demographic and cardiovascular risk groups: The application of a novel modeling strategy in a large multiethnic cohort study. American Journal Of Preventive Cardiology 2023, 14: 100493. PMID: 37397263, PMCID: PMC10314135, DOI: 10.1016/j.ajpc.2023.100493.
- Chui P, Lan Z, Freeman J, Enriquez A, Khera R, Akar J, Masoudi F, Ong E, Curtis J. Variation in hospital use of cardiac resynchronization therapy-defibrillator among eligible patients and association with clinical outcomes. Heart Rhythm 2023, 20: 1000-1008. PMID: 36963741, DOI: 10.1016/j.hrthm.2023.03.022.
- Liu Y, Herrin J, Huang C, Khera R, Dhingra L, Dong W, Mortazavi B, Krumholz H, Lu Y. Nonexercise machine learning models for maximal oxygen uptake prediction in national population surveys. Journal Of The American Medical Informatics Association 2023, 30: 943-952. PMID: 36905605, PMCID: PMC10114129, DOI: 10.1093/jamia/ocad035.
- Lu Y, Linderman G, Mahajan S, Liu Y, Huang C, Khera R, Mortazavi B, Spatz E, Krumholz H. Quantifying Blood Pressure Visit-to-Visit Variability in the Real-World Setting: A Retrospective Cohort Study. Circulation Cardiovascular Quality And Outcomes 2023, 16: e009258. PMID: 36883456, DOI: 10.1161/circoutcomes.122.009258.
- Khunte A, Sangha V, Dhingra L, Oikonomou E, Mortazavi B, Khera R. DEEP LEARNING-BASED DETECTION OF LEFT VENTRICULAR SYSTOLIC DYSFUNCTION FROM NOISY SINGLE LEAD ELECTROCARDIOGRAPHY ADAPTED FOR WEARABLE DEVICES. Journal Of The American College Of Cardiology 2023, 81: 2262. DOI: 10.1016/s0735-1097(23)02706-7.
- Khera R, Loccoh E, Nguyen A, Li D, Chase L, Warraich H. MARKUP ON COMMON GENERIC MEDICATIONS AT HOSPITALS IN THE UNITED STATES: A NATIONALLY REPRESENTATIVE EVALUATION. Journal Of The American College Of Cardiology 2023, 81: 1667. DOI: 10.1016/s0735-1097(23)02111-3.
- Oikonomou E, Suchard M, Miller E, Velazquez E, Khera R. MECHANISTIC EVALUATION OF AN AI-DRIVEN CLINICAL DECISION SUPPORT TOOL TO PERSONALIZE THE USE OF ANATOMICAL TESTING IN SUSPECTED CORONARY ARTERY DISEASE. Journal Of The American College Of Cardiology 2023, 81: 1360. DOI: 10.1016/s0735-1097(23)01804-1.
- Sangha V, Khunte A, Holste G, Mortazavi B, Wang Z, Oikonomou E, Khera R. BIOMETRIC CONTRASTIVE MODELING FOR DATA-EFFICIENT DEEP LEARNING FROM ELECTROCARDIOGRAPHIC IMAGES. Journal Of The American College Of Cardiology 2023, 81: 2403. DOI: 10.1016/s0735-1097(23)02847-4.
- Sangha V, Oikonomou E, Khunte A, Gupta K, Mortazavi B, Khera R. SMART-AS: A NOVEL ARTIFICIAL INTELLIGENCE TOOL TO DETECT SEVERE AORTIC STENOSIS FROM ELECTROCARDIOGRAPHIC IMAGES. Journal Of The American College Of Cardiology 2023, 81: 2409. DOI: 10.1016/s0735-1097(23)02853-x.
- Nargesi A, Rosand B, Hengartner A, Adejumo P, Khera R. DEEP LEARNING-BASED IDENTIFICATION OF HEART FAILURE WITH REDUCED EJECTION FRACTION IN CLINICAL DOCUMENTATION TO AUTOMATE CARE QUALITY ASSESSMENT IN HEART FAILURE. Journal Of The American College Of Cardiology 2023, 81: 2302. DOI: 10.1016/s0735-1097(23)02746-8.
- Khera R, Dhingra L, Li K, Aminorroaya A, Zhou J, Arshad F, Bu F, Dorr D, Falconer T, French T, Lau W, Lu Y, Man K, Matheny M, Minty E, Nishimura A, Ostropolets A, Seager S, Y.F. W, Yang J, Yin C, Hripcsak G, Krumholz H. MULTINATIONAL PATTERNS OF SECOND-LINE ANTI-HYPERGLYCEMIC DRUG INITIATION IN ESTABLISHED CARDIOVASCULAR DISEASE: A FEDERATED PHARMACOEPIDEMIOLOGIC EVALUATION IN LEGEND-T2DM. Journal Of The American College Of Cardiology 2023, 81: 1646. DOI: 10.1016/s0735-1097(23)02090-9.
- Sawano M, Lu Y, Caraballo C, Mahajan S, Dreyer R, Lichtman J, D'Onofrio G, Spatz E, Khera R, Onuma O, Murugiah K, Spertus J, Krumholz H. SEX DIFFERENCE IN CAUSES AND TIMING OF ONE-YEAR OUTCOMES AMONG YOUNG ACUTE MYOCARDIAL INFARCTION PATIENTS; RESULTS FROM THE VIRGO STUDY. Journal Of The American College Of Cardiology 2023, 81: 1294. DOI: 10.1016/s0735-1097(23)01738-2.
- Oikonomou E, Spatz E, Ross J, Suchard M, Krumholz H, Khera R. A MACHINE LEARNING-GUIDED APPROACH FOR ADAPTIVE TRIAL ENRICHMENT AND ACCELERATION OF CARDIOVASCULAR OUTCOME TRIALS: INSIGHTS FROM THE SPRINT AND ACCORD-BP TRIALS. Journal Of The American College Of Cardiology 2023, 81: 2314. DOI: 10.1016/s0735-1097(23)02758-4.
- Nabi W, Aminorroaya A, Khera R. Abstract P445: Patterns in Physical Activity Among Individuals With Cardiovascular Risk Factors in the United States: A Population-Based Contemporary Study From NHANES 2017- 2020. Circulation 2023, 147: ap445-ap445. DOI: 10.1161/circ.147.suppl_1.p445.
- MCCLOSKEY V, Nasir K, Khera R, Oikonomou E, Diaz R, Kenney R, Aguilar R, Gulati M, Cingolani O, Gluckman T, Blankstein R, Hernandez M, Rivera J. Abstract 60: Impact of a Multisite, Protocol-Driven, Nurse Practitioner-Led, Cardiovascular Prevention Program in a Hispanic Medicare Advantage Population at High Risk for ASCVD: Healthy Heart Program at Cano Health. Circulation 2023, 147: a60-a60. DOI: 10.1161/circ.147.suppl_1.60.
- Loccoh E, Khera R, van Meijgaard J, Marsh T, Warraich H. Hospital Adherence to the Federal Price Transparency Mandate: Results from a Nationally Representative Sample. Journal Of General Internal Medicine 2023, 38: 2424-2427. PMID: 36650327, PMCID: PMC10406987, DOI: 10.1007/s11606-023-08039-0.
- Caraballo C, Mahajan S, Murugiah K, Mortazavi B, Lu Y, Khera R, Krumholz H. Timing of Blood Draws Among Patients Hospitalized in a Large Academic Medical Center. JAMA 2023, 329: 255-257. PMID: 36648476, PMCID: PMC9856620, DOI: 10.1001/jama.2022.21509.
- Valero-Elizondo J, Javed Z, Khera R, Tano M, Dudum R, Acquah I, Hyder A, Andrieni J, Sharma G, Blaha M, Virani S, Blankstein R, Cainzos-Achirica M, Nasir K. Unfavorable social determinants of health are associated with higher burden of financial toxicity among patients with atherosclerotic cardiovascular disease in the US: findings from the National Health Interview Survey. Archives Of Public Health 2022, 80: 248. PMID: 36474300, PMCID: PMC9727868, DOI: 10.1186/s13690-022-00987-z.
- Wheelock K, Chan P, Chen L, de Lemos J, Miller P, Nallamothu B, Girotra S, Khera R. Time in therapeutic range for targeted temperature management and outcomes following out-of-hospital cardiac arrest. Resuscitation 2022, 182: 109650. PMID: 36442596, PMCID: PMC9885789, DOI: 10.1016/j.resuscitation.2022.11.016.
- Agusala V, Dale P, Khera R, Brown S, Idris A, Link M, Mody P. Variation in coronary angiography use in Out-of-Hospital cardiac arrest. Resuscitation 2022, 181: 79-85. PMID: 36332772, DOI: 10.1016/j.resuscitation.2022.10.020.
- Shen M, Nargesi A, Nasir K, Bhatt DL, Khera R. Contemporary National Patterns of Eligibility and Use of Novel Lipid‐Lowering Therapies in the United States. Journal Of The American Heart Association 2022, 11: e026075. PMID: 36102276, PMCID: PMC9683659, DOI: 10.1161/jaha.122.026075.
- Siddiqi TJ, Ahmed A, Greene SJ, Shahid I, Usman MS, Oshunbade A, Alkhouli M, Hall ME, Murad MH, Khera R, Jain V, Van Spall HGC, Khan MS. Performance of current risk stratification models for predicting mortality in patients with heart failure: a systematic review and meta-analysis. European Journal Of Preventive Cardiology 2022, 29: 2027-2048. PMID: 35919956, DOI: 10.1093/eurjpc/zwac148.
- Mori M, Mark DB, Khera R, Lin H, Jones P, Huang C, Lu Y, Geirsson A, Velazquez EJ, Spertus JA, Krumholz HM. Identifying quality of life outcome patterns to inform treatment choices in ischemic cardiomyopathy. American Heart Journal 2022, 254: 12-22. PMID: 35932911, DOI: 10.1016/j.ahj.2022.07.007.
- Hanna J, Nargesi AA, Essien UR, Sangha V, Lin Z, Krumholz HM, Khera R. County-level variation in cardioprotective antihyperglycemic prescribing among medicare beneficiaries. American Journal Of Preventive Cardiology 2022, 11: 100370. PMID: 35968531, PMCID: PMC9364091, DOI: 10.1016/j.ajpc.2022.100370.
- Ali HR, Valero-Elizondo J, Wang SY, Cainzos-Achirica M, Bhimaraj A, Khan SU, Khan MS, Mossialos E, Khera R, Nasir K. Subjective Financial Hardship due to Medical Bills Among Patients With Heart Failure in the United States: The 2014–2018 Medical Expenditure Panel Survey. Journal Of Cardiac Failure 2022, 28: 1424-1433. PMID: 35839928, DOI: 10.1016/j.cardfail.2022.06.009.
- Wang SY, Valero-Elizondo J, Cainzos-Achirica M, Desai NR, Nasir K, Khera R. Measures of Financial Hardship From Health Care Expenses Among Families With a Member With Atherosclerotic Cardiovascular Disease in the US. JAMA Health Forum 2022, 3: e221962. PMID: 35977226, PMCID: PMC9308060, DOI: 10.1001/jamahealthforum.2022.1962.
- Khera R, Schuemie MJ, Lu Y, Ostropolets A, Chen R, Hripcsak G, Ryan PB, Krumholz HM, Suchard MA. Large-scale evidence generation and evaluation across a network of databases for type 2 diabetes mellitus (LEGEND-T2DM): a protocol for a series of multinational, real-world comparative cardiovascular effectiveness and safety studies. BMJ Open 2022, 12: e057977. PMID: 35680274, PMCID: PMC9185490, DOI: 10.1136/bmjopen-2021-057977.
- Minhas AMK, Sheikh AB, Ijaz SH, Mostafa A, Nazir S, Khera R, Loccoh EC, Warraich HJ. Rural-Urban Disparities in Heart Failure and Acute Myocardial Infarction Hospitalizations. The American Journal Of Cardiology 2022, 175: 164-169. PMID: 35577603, DOI: 10.1016/j.amjcard.2022.04.014.
- Pareek M, Steele J, Asnes J, Baldassarre L, Casale L, Desai N, Elder R, Faherty E, Ferguson I, Fishman R, Ghazizadeh Z, Glick L, Hall E, Khera R, Kokkinidis D, Kwan J, O'Marr J, Schussheim A, Tuohy E, Wang Y, Spatz E, Jacoby D, Miller E. Short-Term Outcomes After Myopericarditis Related to COVID-19 Vaccination. JACC Cardiovascular Imaging 2022, 15: 2002-2005. PMID: 36357140, PMCID: PMC9094612, DOI: 10.1016/j.jcmg.2022.03.026.
- Lu Y, Li SX, Liu Y, Rodriguez F, Watson KE, Dreyer RP, Khera R, Murugiah K, D’Onofrio G, Spatz ES, Nasir K, Masoudi FA, Krumholz HM. Sex-Specific Risk Factors Associated With First Acute Myocardial Infarction in Young Adults. JAMA Network Open 2022, 5: e229953. PMID: 35503221, PMCID: PMC9066284, DOI: 10.1001/jamanetworkopen.2022.9953.
- Sheppard J, Huang C, Mortazavi B, Schulz W, Krumholz H, Khera R. Abstract 242: Assessing Variation In Data Captured By Clinical Registries And The Electronic Health Record: Clinical Phenotypes Of Patients Undergoing Cardiac Catheterization. Circulation Cardiovascular Quality And Outcomes 2022, 15 DOI: 10.1161/circoutcomes.15.suppl_1.242.
- Hendren N, Peltz M, Khera R, Koch S, Young J, Starling R, Tang W, Pandey A, Drazner M, Grodin J. Association Between Center Level Characteristics And 1-Month Post-LVAD Implant Risk Standardized Mortality Rates. Journal Of Cardiac Failure 2022, 28: s59. DOI: 10.1016/j.cardfail.2022.03.151.
- Murugiah K, Chen L, Dreyer RP, Bouras G, Safdar B, Lu Y, Spatz ES, Gupta A, Khera R, Ng VG, Bueno H, Tweet MS, Spertus JA, Hayes SN, Lansky A, Krumholz HM. Depression and Perceived Stress After Spontaneous Coronary Artery Dissection and Comparison With Other Acute Myocardial Infarction (the VIRGO Experience). The American Journal Of Cardiology 2022, 173: 33-38. PMID: 35365290, PMCID: PMC9133198, DOI: 10.1016/j.amjcard.2022.03.005.
- Sangha V, Mortazavi BJ, Haimovich AD, Ribeiro AH, Brandt CA, Jacoby DL, Schulz WL, Krumholz HM, Ribeiro ALP, Khera R. Automated multilabel diagnosis on electrocardiographic images and signals. Nature Communications 2022, 13: 1583. PMID: 35332137, PMCID: PMC8948243, DOI: 10.1038/s41467-022-29153-3.
- Murugiah K, Chen L, Dreyer RP, Bouras G, Safdar B, Khera R, Lu Y, Spatz ES, Ng VG, Gupta A, Bueno H, Tweet MS, Spertus JA, Hayes SN, Lansky A, Krumholz HM. Health status outcomes after spontaneous coronary artery dissection and comparison with other acute myocardial infarction: The VIRGO experience. PLOS ONE 2022, 17: e0265624. PMID: 35320296, PMCID: PMC8942215, DOI: 10.1371/journal.pone.0265624.
- Khera R, Mortazavi BJ, Sangha V, Warner F, Patrick Young H, Ross JS, Shah ND, Theel ES, Jenkinson WG, Knepper C, Wang K, Peaper D, Martinello RA, Brandt CA, Lin Z, Ko AI, Krumholz HM, Pollock BD, Schulz WL. A multicenter evaluation of computable phenotyping approaches for SARS-CoV-2 infection and COVID-19 hospitalizations. Npj Digital Medicine 2022, 5: 27. PMID: 35260762, PMCID: PMC8904579, DOI: 10.1038/s41746-022-00570-4.
- Oikonomou EK, Suchard MA, McGuire DK, Khera R. Phenomapping-Derived Tool to Individualize the Effect of Canagliflozin on Cardiovascular Risk in Type 2 Diabetes. Diabetes Care 2022, 45: 965-974. PMID: 35120199, PMCID: PMC9016734, DOI: 10.2337/dc21-1765.
- Taha MB, Valero-Elizondo J, Yahya T, Caraballo C, Khera R, Patel KV, Ali HJR, Sharma G, Mossialos E, Cainzos-Achirica M, Nasir K. Cost-Related Medication Nonadherence in Adults With Diabetes in the United States: The National Health Interview Survey 2013-2018. Diabetes Care 2022, 45: 594-603. PMID: 35015860, DOI: 10.2337/dc21-1757.
- Wheelock KM, Ross JS, Murugiah K, Lin Z, Krumholz HM, Khera R. Clinician Trends in Prescribing Direct Oral Anticoagulants for US Medicare Beneficiaries. JAMA Network Open 2021, 4: e2137288. PMID: 34870678, PMCID: PMC8649845, DOI: 10.1001/jamanetworkopen.2021.37288.
- Khera R, Mortazavi BJ, Krumholz HM. Assessing Performance of Machine Learning—Reply. JAMA Cardiology 2021, 6: 1466-1466. PMID: 34586344, DOI: 10.1001/jamacardio.2021.3715.
- Sangha V, Lipska K, Lin Z, Inzucchi SE, McGuire DK, Krumholz HM, Khera R. Patterns of Prescribing Sodium-Glucose Cotransporter-2 Inhibitors for Medicare Beneficiaries in the United States. Circulation Cardiovascular Quality And Outcomes 2021, 14: e008381. PMID: 34779654, PMCID: PMC9022137, DOI: 10.1161/circoutcomes.121.008381.
- Fudim M, Zhong L, Patel KV, Khera R, Abdelmalek MF, Diehl AM, McGarrah RW, Molinger J, Moylan CA, Rao VN, Wegermann K, Neeland IJ, Halm EA, Das SR, Pandey A. Nonalcoholic Fatty Liver Disease and Risk of Heart Failure Among Medicare Beneficiaries. Journal Of The American Heart Association 2021, 10: e021654. PMID: 34755544, PMCID: PMC8751938, DOI: 10.1161/jaha.121.021654.
- Khera R. Digital Cardiovascular Epidemiology—Ushering in a New Era Through Computational Phenotyping of Cardiovascular Disease. JAMA Network Open 2021, 4: e2135561. PMID: 34807263, DOI: 10.1001/jamanetworkopen.2021.35561.
- Murugiah K, Chen L, Castro-Dominguez Y, Khera R, Krumholz HM. Scope of Practice of US Interventional Cardiologists from an Analysis of Medicare Billing Data. The American Journal Of Cardiology 2021, 160: 40-45. PMID: 34610872, DOI: 10.1016/j.amjcard.2021.08.041.
- Prasanna S, Premnath N, Angraal S, Sedhom R, Khera R, Parsons H, Hussaini S, Johnson P, Lou E, Beg M, Subbiah I, Rao P, Gupta A. Sentiment analysis of tweets on prior authorization. Journal Of Clinical Oncology 2021, 39: 322-322. DOI: 10.1200/jco.2020.39.28_suppl.322.
- Lago‐Hernandez C, Nguyen NH, Khera R, Loomba R, Asrani SK, Singh S. Financial Hardship From Medical Bills Among Adults With Chronic Liver Diseases: National Estimates From the United States. Hepatology 2021, 74: 1509-1522. PMID: 33772833, DOI: 10.1002/hep.31835.
- Mahajan S, Grandhi GR, Valero‐Elizondo J, Mszar R, Khera R, Acquah I, Yahya T, Virani SS, Blankstein R, Blaha MJ, Cainzos‐Achirica M, Nasir K. Scope and Social Determinants of Food Insecurity Among Adults With Atherosclerotic Cardiovascular Disease in the United States. Journal Of The American Heart Association 2021, 10: e020028. PMID: 34387089, PMCID: PMC8475063, DOI: 10.1161/jaha.120.020028.
- Thomas A, Valero-Elizondo J, Khera R, Warraich HJ, Reinhardt SW, Ali HJ, Nasir K, Desai NR. Forgone Medical Care Associated With Increased Health Care Costs Among the U.S. Heart Failure Population. JACC Heart Failure 2021, 9: 710-719. PMID: 34391737, DOI: 10.1016/j.jchf.2021.05.010.
- Secemsky EA, Butala N, Raja A, Khera R, Wang Y, Curtis JP, Maddox TM, Virani SS, Armstrong EJ, Shunk KA, Brindis RG, Bhatt D, Yeh RW. Comparative Outcomes of Percutaneous Coronary Intervention for ST-Segment–Elevation Myocardial Infarction Among Medicare Beneficiaries With Multivessel Coronary Artery Disease. Circulation Cardiovascular Interventions 2021, 14: e010323. PMID: 34372676, PMCID: PMC8485756, DOI: 10.1161/circinterventions.120.010323.
- Association of COVID-19 Hospitalization Volume and Case Growth at US Hospitals with Patient OutcomesKhera R, Liu Y, de Lemos JA, Das SR, Pandey A, Omar W, Kumbhani DJ, Girotra S, Yeh RW, Rutan C, Walchok J, Lin Z, Bradley SM, Velazquez EJ, Churchwell KB, Nallamothu BK, Krumholz HM, Curtis JP. Association of COVID-19 Hospitalization Volume and Case Growth at US Hospitals with Patient Outcomes. The American Journal Of Medicine 2021, 134: 1380-1388.e3. PMID: 34343515, PMCID: PMC8325555, DOI: 10.1016/j.amjmed.2021.06.034.
- Huo Z, Zhang L, Khera R, Huang S, Qian X, Wang Z, Mortazavi B. Sparse Gated Mixture-of-Experts to Separate and Interpret Patient Heterogeneity in EHR data. 2021, 00: 1-4. DOI: 10.1109/bhi50953.2021.9508549.
- Bradley SM, Emmons-Bell S, Mutharasan RK, Rodriguez F, Gupta D, Roth G, Gluckman TJ, Shah RU, Wang TY, Khera R, Peterson PN, Das S. Repeated cross-sectional analysis of hydroxychloroquine deimplementation in the AHA COVID-19 CVD Registry. Scientific Reports 2021, 11: 15097. PMID: 34302004, PMCID: PMC8302649, DOI: 10.1038/s41598-021-94203-7.
- Acquah I, Valero-Elizondo J, Javed Z, Ibrahim HN, Patel KV, Ryoo Ali HJ, Menser T, Khera R, Cainzos-Achirica M, Nasir K. Financial Hardship Among Nonelderly Adults With CKD in the United States. American Journal Of Kidney Diseases 2021, 78: 658-668. PMID: 34144103, DOI: 10.1053/j.ajkd.2021.04.011.
- Valero-Elizondo J, Chouairi F, Khera R, Grandhi GR, Saxena A, Warraich HJ, Virani SS, Desai NR, Sasangohar F, Krumholz HM, Esnaola NF, Nasir K. Atherosclerotic Cardiovascular Disease, Cancer, and Financial Toxicity Among Adults in the United States. JACC CardioOncology 2021, 3: 236-246. PMID: 34396329, PMCID: PMC8352280, DOI: 10.1016/j.jaccao.2021.02.006.
- Lago-Hernandez C, Nguyen NH, Khera R, Loomba R, Asrani SK, Singh S. Cost-Related Nonadherence to Medications Among US Adults With Chronic Liver Diseases. Mayo Clinic Proceedings 2021, 96: 2639-2650. PMID: 34120754, PMCID: PMC8492496, DOI: 10.1016/j.mayocp.2021.02.026.
- Rao A, Ranka S, Ayers C, Hendren N, Rosenblatt A, Alger HM, Rutan C, Omar W, Khera R, Gupta K, Mody P, DeFilippi C, Das SR, Hedayati SS, de Lemos JA. Association of Kidney Disease With Outcomes in COVID‐19: Results From the American Heart Association COVID‐19 Cardiovascular Disease Registry. Journal Of The American Heart Association 2021, 10: e020910. PMID: 34107743, PMCID: PMC8477855, DOI: 10.1161/jaha.121.020910.
- Khera R, Haimovich J, Hurley NC, McNamara R, Spertus JA, Desai N, Rumsfeld JS, Masoudi FA, Huang C, Normand SL, Mortazavi BJ, Krumholz HM. Use of Machine Learning Models to Predict Death After Acute Myocardial Infarction. JAMA Cardiology 2021, 6: 633-641. PMID: 33688915, PMCID: PMC7948114, DOI: 10.1001/jamacardio.2021.0122.
- Wang SY, Valero‐Elizondo J, Ali H, Pandey A, Cainzos‐Achirica M, Krumholz HM, Nasir K, Khera R. Out‐of‐pocket Annual Health Expenditures and Financial Toxicity from Healthcare Costs in Patients with Heart Failure in the United States. Journal Of The American Heart Association 2021, 10: e022164. PMID: 33998273, PMCID: PMC8483501, DOI: 10.1161/jaha.121.022164.
- Nargesi AA, Jeyashanmugaraja GP, Desai N, Lipska K, Krumholz H, Khera R. Contemporary National Patterns of Eligibility and Utilization of Novel Cardioprotective Anti‐hyperglycemic agents in Type 2 Diabetes. Journal Of The American Heart Association 2021, 10: e021084. PMID: 33998258, PMCID: PMC8403287, DOI: 10.1161/jaha.121.021084.
- Gupta A, Premnath N, Sedhom R, Beg MS, Khera R, Laheru DA, Dusetzina SB. Projected 30- day out-of-pocket costs and total spending on pancreatic enzyme replacement therapy under Medicare Part D. Pancreatology 2021, 21: 1009-1010. PMID: 34006458, DOI: 10.1016/j.pan.2021.05.002.
- Slavin SD, Khera R, Zafar SY, Nasir K, Warraich HJ. Financial burden, distress, and toxicity in cardiovascular disease. American Heart Journal 2021, 238: 75-84. PMID: 33961830, DOI: 10.1016/j.ahj.2021.04.011.
- Secemsky EA, Butala N, Raja A, Khera R, Wang Y, Curtis JP, Maddox TM, Virani SS, Armstrong EJ, Shunk KA, Brindis RG, Bhatt D, Yeh RW. Temporal Changes and Institutional Variation in Use of Percutaneous Coronary Intervention for ST-Elevation Myocardial Infarction With Multivessel Coronary Artery Disease in the United States. JAMA Cardiology 2021, 6: 574-580. PMID: 33146666, PMCID: PMC7643043, DOI: 10.1001/jamacardio.2020.5354.
- Oikonomou EK, Van Dijk D, Parise H, Suchard MA, de Lemos J, Antoniades C, Velazquez EJ, Miller EJ, Khera R. A phenomapping-derived tool to personalize the selection of anatomical vs. functional testing in evaluating chest pain (ASSIST). European Heart Journal 2021, 42: 2536-2548. PMID: 33881513, PMCID: PMC8488385, DOI: 10.1093/eurheartj/ehab223.
- Kunitomo Y, Thomas A, Chouairi F, Canavan ME, Kochar A, Khera R, Katz JN, Murphy C, Jentzer J, Ahmad T, Desai NR, Brennan J, Miller PE. Electronic health record risk score provides earlier prognostication of clinical outcomes in patients admitted to the cardiac intensive care unit. American Heart Journal 2021, 238: 85-88. PMID: 33891906, DOI: 10.1016/j.ahj.2021.04.004.
- Rosario K, Mehta A, Ayers C, Gonzalez P, Pandey A, Khera R, Kaplan R, Blaha MJ, Khera A, Blumenthal RS, Nasir K, Rodriguez CJ, Joshi PH. Performance of the Pooled Cohort Equations in Hispanic Individuals Across the United States: Insights From the Multi‐Ethnic Study of Atherosclerosis and the Dallas Heart Study. Journal Of The American Heart Association 2021, 10: e018410. PMID: 33870702, PMCID: PMC8200750, DOI: 10.1161/jaha.120.018410.
- Yang DX, Khera R, Miccio JA, Jairam V, Chang E, Yu JB, Park HS, Krumholz HM, Aneja S. Prevalence of Missing Data in the National Cancer Database and Association With Overall Survival. JAMA Network Open 2021, 4: e211793. PMID: 33755165, PMCID: PMC7988369, DOI: 10.1001/jamanetworkopen.2021.1793.
- Khera R, Clark C, Lu Y, Guo Y, Ren S, Truax B, Spatz ES, Murugiah K, Lin Z, Omer SB, Vojta D, Krumholz HM. Association of Angiotensin‐Converting Enzyme Inhibitors and Angiotensin Receptor Blockers with the Risk of Hospitalization and Death in Hypertensive Patients with Coronavirus Disease‐19. Journal Of The American Heart Association 2021, 10: e018086. PMID: 33624516, PMCID: PMC8403305, DOI: 10.1161/jaha.120.018086.
- Angraal S, Zachariah AG, Raaisa R, Khera R, Rao P, Krumholz HM, Spertus JA. Evaluation of Internet-Based Crowdsourced Fundraising to Cover Health Care Costs in the United States. JAMA Network Open 2021, 4: e2033157. PMID: 33427882, PMCID: PMC7801937, DOI: 10.1001/jamanetworkopen.2020.33157.
- Hendren NS, de Lemos JA, Ayers C, Das SR, Rao A, Carter S, Rosenblatt A, Walchok J, Omar W, Khera R, Hegde AA, Drazner MH, Neeland IJ, Grodin JL. Association of Body Mass Index and Age With Morbidity and Mortality in Patients Hospitalized With COVID-19. Circulation 2020, 143: 135-144. PMID: 33200947, DOI: 10.1161/circulationaha.120.051936.
- Mori M, Khera R. Pumping the Breaks on Health Care Costs of Cardiac Surgery by Focusing on Postacute Care Spending. Circulation Cardiovascular Quality And Outcomes 2020, 13: e007253. PMID: 33176464, DOI: 10.1161/circoutcomes.120.007253.
- Mszar R, Mahajan S, Valero-Elizondo J, Yahya T, Sharma R, Grandhi GR, Khera R, Virani SS, Lichtman J, Khan SU, Cainzos-Achirica M, Vahidy FS, Krumholz HM, Nasir K. Association Between Sociodemographic Determinants and Disparities in Stroke Symptom Awareness Among US Young Adults. Stroke 2020, 51: 3552-3561. PMID: 33100188, DOI: 10.1161/strokeaha.120.031137.
- Nguyen NH, Khera R, Dulai PS, Boland BS, Ohno-Machado L, Sandborn WJ, Singh S. National Estimates of Financial Hardship From Medical Bills and Cost-related Medication Nonadherence in Patients With Inflammatory Bowel Diseases in the United States. Inflammatory Bowel Diseases 2020, 27: 1068-1078. PMID: 33051681, PMCID: PMC8205631, DOI: 10.1093/ibd/izaa266.
- Mori M, Wang Y, Murugiah K, Khera R, Gupta A, Vallabhajosyula P, Masoudi FA, Geirsson A, Krumholz HM. Trends in Reoperative Coronary Artery Bypass Graft Surgery for Older Adults in the United States, 1998 to 2017. Journal Of The American Heart Association 2020, 9: e016980. PMID: 33045889, PMCID: PMC7763387, DOI: 10.1161/jaha.120.016980.
- Khera R, Pandey A, Ayers CR, Carnethon MR, Greenland P, Ndumele CE, Nambi V, Seliger SL, Chaves PHM, Safford MM, Cushman M, Xanthakis V, Ramachandran V, Mentz RJ, Correa A, Lloyd-Jones DM, Berry JD, de Lemos JA, Neeland IJ. Performance of the Pooled Cohort Equations to Estimate Atherosclerotic Cardiovascular Disease Risk by Body Mass Index. JAMA Network Open 2020, 3: e2023242. PMID: 33119108, PMCID: PMC7596579, DOI: 10.1001/jamanetworkopen.2020.23242.
- Khera R, Kondamudi N, Zhong L, Vaduganathan M, Parker J, Das SR, Grodin JL, Halm EA, Berry JD, Pandey A. Temporal Trends in Heart Failure Incidence Among Medicare Beneficiaries Across Risk Factor Strata, 2011 to 2016. JAMA Network Open 2020, 3: e2022190. PMID: 33095250, PMCID: PMC7584929, DOI: 10.1001/jamanetworkopen.2020.22190.
- Khera R, Secemsky EA, Wang Y, Desai NR, Krumholz HM, Maddox TM, Shunk KA, Virani SS, Bhatt DL, Curtis J, Yeh RW. Revascularization Practices and Outcomes in Patients With Multivessel Coronary Artery Disease Who Presented With Acute Myocardial Infarction and Cardiogenic Shock in the US, 2009-2018. JAMA Internal Medicine 2020, 180: 1317-1327. PMID: 32833024, PMCID: PMC9377424, DOI: 10.1001/jamainternmed.2020.3276.
- Martinez-Amezcua P, Haque W, Khera R, Kanaya AM, Sattar N, Lam CSP, Harikrishnan S, Shah SJ, Kandula NR, Jose PO, Narayan KMV, Agyemang C, Misra A, Jenum AK, Bilal U, Nasir K, Cainzos-Achirica M. The Upcoming Epidemic of Heart Failure in South Asia. Circulation Heart Failure 2020, 13: e007218. PMID: 32962410, DOI: 10.1161/circheartfailure.120.007218.
- Khera R, Valero-Elizondo J, Nasir K. Financial Toxicity in Atherosclerotic Cardiovascular Disease in the United States: Current State and Future Directions. Journal Of The American Heart Association 2020, 9: e017793. PMID: 32924728, PMCID: PMC7792407, DOI: 10.1161/jaha.120.017793.
- Murugiah K, Annapureddy AR, Khera R, Lansky A, Curtis JP. Characteristics of cardiac catheterization laboratory directors at the 2017 U.S. News & World Report top 100 U.S. cardiovascular hospitals. Catheterization And Cardiovascular Interventions 2020, 97: e624-e626. PMID: 32833350, DOI: 10.1002/ccd.29217.
- Nasir K, Khera R. Digital Phenotyping of Myocardial Dysfunction With 12-Lead ECG Tiptoeing Into the Future With Machine Learning ∗. Journal Of The American College Of Cardiology 2020, 76: 942-944. PMID: 32819468, DOI: 10.1016/j.jacc.2020.07.001.
- Financial Hardship After Traumatic Injury: Risk Factors and Drivers of Out-of-Pocket Health ExpensesO'Neill KM, Jean RA, Gross CP, Becher RD, Khera R, Elizondo JV, Nasir K. Financial Hardship After Traumatic Injury: Risk Factors and Drivers of Out-of-Pocket Health Expenses. Journal Of Surgical Research 2020, 256: 1-12. PMID: 32663705, DOI: 10.1016/j.jss.2020.05.095.
- Mori M, Khera R, Lin Z, Ross JS, Schulz W, Krumholz HM. The Promise of Big Data and Digital Solutions in Building a Cardiovascular Learning System: Opportunities and Barriers. Methodist DeBakey Cardiovascular Journal 2020, 16: 212-219. PMID: 33133357, PMCID: PMC7587314, DOI: 10.14797/mdcj-16-3-212.
- Caraballo C, Khera R, Jones PG, Decker C, Schulz W, Spertus JA, Krumholz HM. Rates and Predictors of Patient Underreporting of Hospitalizations During Follow-Up After Acute Myocardial Infarction. Circulation Cardiovascular Quality And Outcomes 2020, 13: e006231. PMID: 32552061, PMCID: PMC9465954, DOI: 10.1161/circoutcomes.119.006231.
- Nguyen NH, Khera R, Ohno-Machado L, Sandborn WJ, Singh S. Prevalence and Effects of Food Insecurity and Social Support on Financial Toxicity in and Healthcare Use by Patients With Inflammatory Bowel Diseases. Clinical Gastroenterology And Hepatology 2020, 19: 1377-1386.e5. PMID: 32526341, PMCID: PMC7987215, DOI: 10.1016/j.cgh.2020.05.056.
- Khera R, Dhingra LS, Jain S, Krumholz HM. An Evaluation of the Vulnerable Physician Workforce in the USA During the Coronavirus Disease-19 Pandemic. Journal Of General Internal Medicine 2020, 35: 3114-3116. PMID: 32495101, PMCID: PMC7269617, DOI: 10.1007/s11606-020-05854-7.
- Grandhi GR, Valero-Elizondo J, Mszar R, Brandt EJ, Annapureddy A, Khera R, Saxena A, Virani SS, Blankstein R, Desai NR, Blaha MJ, Cheema FH, Vahidy FS, Nasir K. Association of cardiovascular risk factor profile and financial hardship from medical bills among non-elderly adults in the United States. American Journal Of Preventive Cardiology 2020, 2: 100034. PMID: 34327457, PMCID: PMC8315456, DOI: 10.1016/j.ajpc.2020.100034.
- Khera R. Do or Do Not, There Is No Try. Circulation Cardiovascular Quality And Outcomes 2020, 13: e006693. PMID: 32393124, DOI: 10.1161/circoutcomes.120.006693.
- Mszar R, Grandhi GR, Valero‐Elizondo J, Caraballo C, Khera R, Desai N, Virani SS, Blankstein R, Blaha MJ, Nasir K. Cumulative Burden of Financial Hardship From Medical Bills Across the Spectrum of Diabetes Mellitus and Atherosclerotic Cardiovascular Disease Among Non‐Elderly Adults in the United States. Journal Of The American Heart Association 2020, 9: e015523. PMID: 32394783, PMCID: PMC7660844, DOI: 10.1161/jaha.119.015523.
- Khera R, Girotra S. Cerebral Embolic Protection Devices in Transcatheter Aortic Valve Replacement—Effective in Stroke Prevention? JAMA Internal Medicine 2020, 180: 785-786. PMID: 32091530, DOI: 10.1001/jamainternmed.2019.6763.
- Jain S, Khera R, Lin Z, Ross JS, Krumholz HM. Availability of Telemedicine Services Across Hospitals in the United States in 2018: A Cross-sectional Study. Annals Of Internal Medicine 2020, 173: m20-1201. PMID: 32353106, PMCID: PMC7212823, DOI: 10.7326/m20-1201.
- Caraballo C, Valero-Elizondo J, Khera R, Mahajan S, Grandhi GR, Virani SS, Mszar R, Krumholz HM, Nasir K. Burden and Consequences of Financial Hardship From Medical Bills Among Nonelderly Adults With Diabetes Mellitus in the United States. Circulation Cardiovascular Quality And Outcomes 2020, 13: e006139. PMID: 32069093, DOI: 10.1161/circoutcomes.119.006139.
- Pandey A, Keshvani N, Khera R, Lu D, Vaduganathan M, Maddox K, Das SR, Kumbhani DJ, Goyal A, Girotra S, Chan P, Fonarow GC, Matsouaka R, Wang TY, de Lemos JA. Temporal Trends in Racial Differences in 30-Day Readmission and Mortality Rates After Acute Myocardial Infarction Among Medicare Beneficiaries. JAMA Cardiology 2020, 5: 136-145. PMID: 31913411, PMCID: PMC6990949, DOI: 10.1001/jamacardio.2019.4845.
- Ko DT, Khera R, Lau G, Qiu F, Wang Y, Austin PC, Koh M, Lin Z, Lee DS, Wijeysundera HC, Krumholz HM. Readmission and Mortality After Hospitalization for Myocardial Infarction and Heart Failure. Journal Of The American College Of Cardiology 2020, 75: 736-746. PMID: 32081282, DOI: 10.1016/j.jacc.2019.12.026.
- Khera R, Wang Y, Bernheim SM, Lin Z, Krumholz HM. Post-discharge acute care and outcomes following readmission reduction initiatives: national retrospective cohort study of Medicare beneficiaries in the United States. The BMJ 2020, 368: l6831. PMID: 31941686, PMCID: PMC7190056, DOI: 10.1136/bmj.l6831.
- Mahajan S, Valero-Elizondo J, Khera R, Desai NR, Blankstein R, Blaha MJ, Virani SS, Kash BA, Zoghbi WA, Krumholz HM, Nasir K. Variation and Disparities in Awareness of Myocardial Infarction Symptoms Among Adults in the United States. JAMA Network Open 2019, 2: e1917885. PMID: 31851350, PMCID: PMC6991230, DOI: 10.1001/jamanetworkopen.2019.17885.
- Khera R, Valero-Elizondo J, Das SR, Virani SS, Kash BA, de Lemos JA, Krumholz HM, Nasir K. Cost-Related Medication Nonadherence in Adults With Atherosclerotic Cardiovascular Disease in the United States, 2013 to 2017. Circulation 2019, 140: 2067-2075. PMID: 31760784, DOI: 10.1161/circulationaha.119.041974.
- Angraal S, Mortazavi BJ, Gupta A, Khera R, Ahmad T, Desai NR, Jacoby DL, Masoudi FA, Spertus JA, Krumholz HM. Machine Learning Prediction of Mortality and Hospitalization in Heart Failure With Preserved Ejection Fraction. JACC Heart Failure 2019, 8: 12-21. PMID: 31606361, DOI: 10.1016/j.jchf.2019.06.013.
- Mahajan S, Gu J, Lu Y, Khera R, Spatz ES, Zhang M, Sun N, Zheng X, Zhao H, Lu H, Ma ZJ, Krumholz HM. Hemodynamic Phenotypes of Hypertension Based on Cardiac Output and Systemic Vascular Resistance. The American Journal Of Medicine 2019, 133: e127-e139. PMID: 31525336, DOI: 10.1016/j.amjmed.2019.08.042.
- Miller PE, Guha A, Khera R, Chouairi F, Ahmad T, Nasir K, Addison D, Desai NR. National Trends in Healthcare-Associated Infections for Five Common Cardiovascular Conditions. The American Journal Of Cardiology 2019, 124: 1140-1148. PMID: 31371062, PMCID: PMC7883647, DOI: 10.1016/j.amjcard.2019.06.029.
- Khera R, Wang Y, Nasir K, Lin Z, Krumholz HM. Evaluation of 30-Day Hospital Readmission and Mortality Rates Using Regression-Discontinuity Framework. Journal Of The American College Of Cardiology 2019, 74: 219-234. PMID: 31296295, PMCID: PMC8669780, DOI: 10.1016/j.jacc.2019.04.060.
- Agusala V, Khera R, Cheeran D, Mody P, Reddy PP, Link MS. Diagnostic and prognostic utility of cardiac troponin in post-cardiac arrest care. Resuscitation 2019, 141: 69-72. PMID: 31201884, DOI: 10.1016/j.resuscitation.2019.06.004.
- Hong JC, Yang GK, Delarmente BA, Khera R, Price J, Faulds J, Chen JC. Cost-minimization study of the percutaneous approach to endovascular aortic aneurysm repair. Journal Of Vascular Surgery 2019, 71: 444-449. PMID: 31176637, DOI: 10.1016/j.jvs.2019.03.040.
- Mody P, Kulkarni N, Khera R, Link MS. Targeted temperature management for cardiac arrest. Progress In Cardiovascular Diseases 2019, 62: 272-278. PMID: 31078561, DOI: 10.1016/j.pcad.2019.05.007.
- Nasir K, Khera R. Financial Toxicity of Acute Cardiovascular Disease in India. JAMA Network Open 2019, 2: e193839. PMID: 31099855, DOI: 10.1001/jamanetworkopen.2019.3839.
- Khera R, Tang Y, Girotra S, Nadkarni VM, Link MS, Raymond TT, Guerguerian AM, Berg RA, Chan PS, Investigators F. Pulselessness After Initiation of Cardiopulmonary Resuscitation for Bradycardia in Hospitalized Children. Circulation 2019, 140: 370-378. PMID: 31006260, PMCID: PMC6663562, DOI: 10.1161/circulationaha.118.039048.
- DeZorzi C, Boyle B, Qazi A, Luthra K, Khera R, Chan PS, Girotra S. Administrative Billing Codes for Identifying Patients With Cardiac Arrest. Journal Of The American College Of Cardiology 2019, 73: 1598-1600. PMID: 30922482, PMCID: PMC6625314, DOI: 10.1016/j.jacc.2019.01.030.
- Angraal S, Gupta A, Khera R, Nasir K, Desai NR. Association of access to exercise opportunities and cardiovascular mortality. American Heart Journal 2019, 212: 152-156. PMID: 31051426, DOI: 10.1016/j.ahj.2019.02.010.
- Ball S, Brown TJ, Das A, Khera R, Khanna S, Gupta A. Effect of Neutropenic Diet on Infection Rates in Cancer Patients With Neutropenia. American Journal Of Clinical Oncology 2019, 42: 270-274. PMID: 30628912, DOI: 10.1097/coc.0000000000000514.
- Khera R, Tang Y, Link MS, Krumholz HM, Girotra S, Chan PS. Association Between Hospital Recognition for Resuscitation Guideline Adherence and Rates of Survival for In-Hospital Cardiac Arrest. Circulation Cardiovascular Quality And Outcomes 2019, 12: e005429. PMID: 30871337, PMCID: PMC6592630, DOI: 10.1161/circoutcomes.118.005429.
- Okunrintemi V, Khera R, Spatz ES, Salami JA, Valero-Elizondo J, Warraich HJ, Virani SS, Blankstein R, Blaha MJ, Pawlik TM, Dharmarajan K, Krumholz HM, Nasir K. Association of Income Disparities with Patient-Reported Healthcare Experience. Journal Of General Internal Medicine 2019, 34: 884-892. PMID: 30783877, PMCID: PMC6544715, DOI: 10.1007/s11606-019-04848-4.
- Valero-Elizondo J, Khera R, Saxena A, Grandhi GR, Virani SS, Butler J, Samad Z, Desai NR, Krumholz HM, Nasir K. Financial Hardship From Medical Bills Among Nonelderly U.S. Adults With Atherosclerotic Cardiovascular Disease. Journal Of The American College Of Cardiology 2019, 73: 727-732. PMID: 30765039, DOI: 10.1016/j.jacc.2018.12.004.
- Huo X, Khera R, Zhang L, Herrin J, Bai X, Wang Q, Lu Y, Nasir K, Hu S, Li J, Li X, Zheng X, Masoudi FA, Spertus JA, Krumholz HM, Jiang L. Education level and outcomes after acute myocardial infarction in China. Heart 2019, 105: 946. PMID: 30661037, PMCID: PMC6582708, DOI: 10.1136/heartjnl-2018-313752.
- Khera R, Krumholz HM. Effects of the Hospital Readmissions Reduction Program. Circulation Cardiovascular Quality And Outcomes 2018, 11: e005083. PMID: 30562071, DOI: 10.1161/circoutcomes.118.005083.
- Khera R, Pandey A, Link MS, Sulistio MS. Managing Implantable Cardioverter-Defibrillators at End-of-Life: Practical Challenges and Care Considerations. The American Journal Of The Medical Sciences 2018, 357: 143-150. PMID: 30665495, DOI: 10.1016/j.amjms.2018.11.016.
- Salami J, Saxena A, Warraich H, Khera R, Okunrintemi V, Valero-Elizondo J, Blaha M, Blankstein R, Virani S, Veledar E, Krumholz H, Nasir K. Abstract 16990: Impact of 2013 ACC/AHA Cholesterol Management Guidelines on Statins Use Among Nationally Representative Adult Populations in United States: Medical Expenditure Panel Survey (2010-2015). Circulation 2018, 138 DOI: 10.1161/circ.138.suppl_1.16990.
- Khera R, Humbert A, Leroux B, Nichol G, Kudenchuk P, Scales D, Baker A, Austin M, Newgard CD, Radecki R, Vilke GM, Sawyer KN, Sopko G, Idris AH, Wang H, Chan PS, Kurz MC. Hospital Variation in the Utilization and Implementation of Targeted Temperature Management in Out-of-Hospital Cardiac Arrest. Circulation Cardiovascular Quality And Outcomes 2018, 11: e004829. PMID: 30571336, DOI: 10.1161/circoutcomes.118.004829.
- Annapureddy A, Valero-Elizondo J, Khera R, Grandhi GR, Spatz ES, Dreyer RP, Desai NR, Krumholz HM, Nasir K. Association Between Financial Burden, Quality of Life, and Mental Health Among Those With Atherosclerotic Cardiovascular Disease in the United States. Circulation Cardiovascular Quality And Outcomes 2018, 11: e005180. PMID: 30571331, DOI: 10.1161/circoutcomes.118.005180.
- Mody P, Brown SP, Kudenchuk PJ, Chan PS, Khera R, Ayers C, Pandey A, Kern K, de Lemos JA, Link MS, Idris AH. Intraosseous versus intravenous access in patients with out-of-hospital cardiac arrest: Insights from the resuscitation outcomes consortium continuous chest compression trial. Resuscitation 2018, 134: 69-75. PMID: 30391366, DOI: 10.1016/j.resuscitation.2018.10.031.
- Khera R, CarlLee S, Blevins A, Schweizer M, Girotra S. Early coronary angiography and survival after out-of-hospital cardiac arrest: a systematic review and meta-analysis. Open Heart 2018, 5: e000809. PMID: 30402255, PMCID: PMC6203043, DOI: 10.1136/openhrt-2018-000809.
- Jain S, Khera R, Mortensen EM, Weissler JC. Readmissions of adults within three age groups following hospitalization for pneumonia: Analysis from the Nationwide Readmissions Database. PLOS ONE 2018, 13: e0203375. PMID: 30212485, PMCID: PMC6136736, DOI: 10.1371/journal.pone.0203375.
- Angraal S, Khera R, Zhou S, Wang Y, Lin Z, Dharmarajan K, Desai NR, Bernheim SM, Drye EE, Nasir K, Horwitz LI, Krumholz HM. Trends in 30-Day Readmission Rates for Medicare and Non-Medicare Patients in the Era of the Affordable Care Act. The American Journal Of Medicine 2018, 131: 1324-1331.e14. PMID: 30016636, PMCID: PMC6380174, DOI: 10.1016/j.amjmed.2018.06.013.
- Khera R, Dharmarajan K, Wang Y, Lin Z, Bernheim SM, Wang Y, Normand ST, Krumholz HM. Association of the Hospital Readmissions Reduction Program With Mortality During and After Hospitalization for Acute Myocardial Infarction, Heart Failure, and Pneumonia. JAMA Network Open 2018, 1: e182777. PMID: 30646181, PMCID: PMC6324473, DOI: 10.1001/jamanetworkopen.2018.2777.
- Rubens M, Saxena A, Ramamoorthy V, Das S, Khera R, Hong J, Armaignac D, Veledar E, Nasir K, Gidel L. Increasing Sepsis Rates in the United States: Results From National Inpatient Sample, 2005 to 2014. Journal Of Intensive Care Medicine 2018, 35: 858-868. PMID: 30175649, DOI: 10.1177/0885066618794136.
- Kumar N, Khera R, Fonarow GC, Bhatt DL. Comparison of Outcomes of Transfemoral Versus Transapical Approach for Transcatheter Aortic Valve Implantation. The American Journal Of Cardiology 2018, 122: 1520-1526. PMID: 30190074, DOI: 10.1016/j.amjcard.2018.07.025.
- Khera R, Valero-Elizondo J, Okunrintemi V, Saxena A, Das SR, de Lemos JA, Krumholz HM, Nasir K. Association of Out-of-Pocket Annual Health Expenditures With Financial Hardship in Low-Income Adults With Atherosclerotic Cardiovascular Disease in the United States. JAMA Cardiology 2018, 3: 729-738. PMID: 29971325, PMCID: PMC6143078, DOI: 10.1001/jamacardio.2018.1813.
- Angraal S, Khera R, Wang Y, Lu Y, Jean R, Dreyer RP, Geirsson A, Desai NR, Krumholz HM. Sex and Race Differences in the Utilization and Outcomes of Coronary Artery Bypass Grafting Among Medicare Beneficiaries, 1999–2014. Journal Of The American Heart Association 2018, 7: e009014. PMID: 30005557, PMCID: PMC6064835, DOI: 10.1161/jaha.118.009014.
- Khera R, Lu Y, Lu J, Saxena A, Nasir K, Jiang L, Krumholz HM. Impact of 2017 ACC/AHA guidelines on prevalence of hypertension and eligibility for antihypertensive treatment in United States and China: nationally representative cross sectional study. The BMJ 2018, 362: k2357. PMID: 29997129, PMCID: PMC6039831, DOI: 10.1136/bmj.k2357.
- Khera R, Dorsey KB, Krumholz HM. Transition to the ICD-10 in the United States: An Emerging Data Chasm. JAMA 2018, 320: 133-134. PMID: 29868861, DOI: 10.1001/jama.2018.6823.
- Khera R, Dharmarajan K, Krumholz HM. Rising Mortality in Patients With Heart Failure in the United States Facts Versus Fiction. JACC Heart Failure 2018, 6: 610-612. PMID: 29914774, DOI: 10.1016/j.jchf.2018.02.011.
- Trends in Use and Expenditures of Brand-name Atorvastatin After Introduction of Generic AtorvastatinWarraich HJ, Salami JA, Khera R, Valero-Elizondo J, Okunrintemi V, Nasir K. Trends in Use and Expenditures of Brand-name Atorvastatin After Introduction of Generic Atorvastatin. JAMA Internal Medicine 2018, 178: 719-721. PMID: 29525818, PMCID: PMC5885171, DOI: 10.1001/jamainternmed.2018.0990.
- Wang S, Khera R, Das SR, Vigen R, Wang T, Luo X, Lu R, Zhan X, Xiao G, Vongpatanasin W, Xie Y. Usefulness of a Simple Algorithm to Identify Hypertensive Patients Who Benefit from Intensive Blood Pressure Lowering. The American Journal Of Cardiology 2018, 122: 248-254. PMID: 29880288, DOI: 10.1016/j.amjcard.2018.03.361.
- Khera R, Horwitz LI, Lin Z, Krumholz HM. Publicly Reported Readmission Measures and the Hospital Readmissions Reduction Program: A False Equivalence? Annals Of Internal Medicine 2018, 168: 670-671. PMID: 29582081, PMCID: PMC8325174, DOI: 10.7326/m18-0536.
- Warraich H, Salami J, Khera R, Okunrintemi V, Nasir K. EXCESS NATIONAL US EXPENDITURES ASSOCIATED WITH LIPITOR USE AFTER INTRODUCTION OF GENERIC ATORVASTATIN: INSIGHTS FROM THE MEDICAL EXPENDITURES PANEL SURVEY, 2012-2014. Journal Of The American College Of Cardiology 2018, 71: a1764. DOI: 10.1016/s0735-1097(18)32305-2.
- Nguyen NH, Khera R, Ohno-Machado L, Sandborn WJ, Singh S. Annual Burden and Costs of Hospitalization for High-Need, High-Cost Patients With Chronic Gastrointestinal and Liver Diseases. Clinical Gastroenterology And Hepatology 2018, 16: 1284-1292.e30. PMID: 29474966, PMCID: PMC6056327, DOI: 10.1016/j.cgh.2018.02.015.
- Pandey A, Khera R, Park B, Haykowsky M, Borlaug BA, Lewis GD, Kitzman DW, Butler J, Berry JD. Relative Impairments in Hemodynamic Exercise Reserve Parameters in Heart Failure With Preserved Ejection Fraction A Study-Level Pooled Analysis. JACC Heart Failure 2018, 6: 117-126. PMID: 29413366, PMCID: PMC8135913, DOI: 10.1016/j.jchf.2017.10.014.
- Rubens M, Saxena A, Ramamoorthy V, Khera R, Hong J, Veledar E, Nasir K. Trends in Diabetes-Related Preventable Hospitalizations in the U.S., 2005–2014. Diabetes Care 2018, 41: dc171942. PMID: 29378777, DOI: 10.2337/dc17-1942.
- Khera R, Pandey A, Chandar AK, Murad MH, Prokop LJ, Neeland IJ, Berry JD, Camilleri M, Singh S. Effects of Weight-Loss Medications on Cardiometabolic Risk Profiles: A Systematic Review and Network Meta-analysis. Gastroenterology 2018, 154: 1309-1319.e7. PMID: 29305933, PMCID: PMC5880739, DOI: 10.1053/j.gastro.2017.12.024.
- Valero-Elizondo J, Hong JC, Spatz ES, Salami JA, Desai NR, Rana JS, Khera R, Virani SS, Blankstein R, Blaha MJ, Nasir K. Persistent socioeconomic disparities in cardiovascular risk factors and health in the United States: Medical Expenditure Panel Survey 2002–2013. Atherosclerosis 2017, 269: 301-305. PMID: 29254694, DOI: 10.1016/j.atherosclerosis.2017.12.014.
- Arrieta A, Hong JC, Khera R, Virani SS, Krumholz HM, Nasir K. Updated Cost-effectiveness Assessments of PCSK9 Inhibitors From the Perspectives of the Health System and Private Payers: Insights Derived From the FOURIER Trial. JAMA Cardiology 2017, 2: 1369-1374. PMID: 29049467, PMCID: PMC5814995, DOI: 10.1001/jamacardio.2017.3655.
- Khera R, Pandey A, Koshy T, Ayers C, Nallamothu BK, Das SR, Drazner MH, Jessen ME, Kirtane AJ, Gardner TJ, de Lemos JA, Bhatt DL, Kumbhani DJ. Role of Hospital Volumes in Identifying Low-Performing and High-Performing Aortic and Mitral Valve Surgical Centers in the United States. JAMA Cardiology 2017, 2: 1322-1331. PMID: 29117319, PMCID: PMC5815001, DOI: 10.1001/jamacardio.2017.4003.
- Khera R, Pandey A. The heart failure readmission quagmire: taking a deep dive to find solutions. European Journal Of Heart Failure 2017, 20: 315-316. PMID: 29193571, DOI: 10.1002/ejhf.1082.
- Khera R, Angraal S, Couch T, Welsh JW, Nallamothu BK, Girotra S, Chan PS, Krumholz HM. Adherence to Methodological Standards in Research Using the National Inpatient Sample. JAMA 2017, 318: 2011-2018. PMID: 29183077, PMCID: PMC5742631, DOI: 10.1001/jama.2017.17653.
- Khera R, Hong JC, Saxena A, Arrieta A, Virani SS, Blankstein R, de Lemos JA, Krumholz HM, Nasir K. Burden of Catastrophic Health Expenditures for Acute Myocardial Infarction and Stroke Among Uninsured in the United States. Circulation 2017, 137: 408-410. PMID: 29133601, PMCID: PMC5780190, DOI: 10.1161/circulationaha.117.030128.
- Khera R, Spertus JA, Starks MA, Tang Y, Bradley SM, Girotra S, Chan PS. Administrative Codes for Capturing In-Hospital Cardiac Arrest. JAMA Cardiology 2017, 2: 1275-1277. PMID: 28877294, PMCID: PMC5736791, DOI: 10.1001/jamacardio.2017.2904.
- Khera R, Pandey A, Ayers CR, Agusala V, Pruitt SL, Halm EA, Drazner MH, Das SR, de Lemos JA, Berry JD. Contemporary Epidemiology of Heart Failure in Fee-For-Service Medicare Beneficiaries Across Healthcare Settings. Circulation Heart Failure 2017, 10: e004402. PMID: 29129828, PMCID: PMC6057614, DOI: 10.1161/circheartfailure.117.004402.
- Kumar N, Khera R, Garg N, Echouffo-Tcheugui JB, Venkatraman A, Pandey A, Bhatt DL. Comparison of Outcomes of Transcatheter Versus Surgical Aortic Valve Replacement in Patients With Chronic Kidney Disease. The American Journal Of Cardiology 2017, 121: 343-348. PMID: 29268936, DOI: 10.1016/j.amjcard.2017.10.029.
- Cheeran D, Khan S, Khera R, Bhatt A, Garg S, Grodin JL, Morlend R, Araj FG, Amin AA, Thibodeau JT, Das S, Drazner MH, Mammen PPA. Predictors of Death in Adults With Duchenne Muscular Dystrophy–Associated Cardiomyopathy. Journal Of The American Heart Association 2017, 6: e006340. PMID: 29042427, PMCID: PMC5721845, DOI: 10.1161/jaha.117.006340.
- Khera R, Jain S, Pandey A, Agusala V, Kumbhani DJ, Das SR, Berry JD, de Lemos JA, Girotra S. Comparison of Readmission Rates After Acute Myocardial Infarction in 3 Patient Age Groups (18 to 44, 45 to 64, and ≥65 Years) in the United States. The American Journal Of Cardiology 2017, 120: 1761-1767. PMID: 28865892, PMCID: PMC5825232, DOI: 10.1016/j.amjcard.2017.07.081.
- Khera R, Krumholz HM. With Great Power Comes Great Responsibility. Circulation Cardiovascular Quality And Outcomes 2017, 10: e003846. PMID: 28705865, PMCID: PMC5728376, DOI: 10.1161/circoutcomes.117.003846.
- Khera R, Kumbhani DJ. Editorial Commentary: Deconstructing the dogma: Its time to untangle and reassess acute myocardial infarction care. Trends In Cardiovascular Medicine 2017, 27: 492-493. PMID: 28760376, DOI: 10.1016/j.tcm.2017.06.010.
- Dulai PS, Singh S, Marquez E, Khera R, Prokop LJ, Limburg PJ, Gupta S, Murad MH. Chemoprevention of colorectal cancer in individuals with previous colorectal neoplasia: systematic review and network meta-analysis. The BMJ 2016, 355: i6188. PMID: 27919915, PMCID: PMC5137632, DOI: 10.1136/bmj.i6188.
- Khera R, Chan PS, Donnino M, Girotra S. Hospital Variation in Time to Epinephrine for Nonshockable In-Hospital Cardiac Arrest. Circulation 2016, 134: 2105-2114. PMID: 27908910, PMCID: PMC5173427, DOI: 10.1161/circulationaha.116.025459.
- Khera R, Pandey A, Kumar N, Singh R, Bano S, Golwala H, Kumbhani DJ, Girotra S, Fonarow GC. Variation in Hospital Use and Outcomes Associated With Pulmonary Artery Catheterization in Heart Failure in the United States. Circulation Heart Failure 2016, 9: e003226. PMID: 27780836, PMCID: PMC5123800, DOI: 10.1161/circheartfailure.116.003226.
- Jain S, Khera R, Girotra S, Badesch D, Wang Z, Murad MH, Blevins A, Schmidt GA, Singh S, Gerke AK. Comparative Effectiveness of Pharmacologic Interventions for Pulmonary Arterial Hypertension A Systematic Review and Network Meta-Analysis. CHEST Journal 2016, 151: 90-105. PMID: 27615023, PMCID: PMC5310124, DOI: 10.1016/j.chest.2016.08.1461.
- Singh S, Khera R, Murad MH, Loomba R. Reply. Hepatology 2016, 64: 694-694. PMID: 26690078, DOI: 10.1002/hep.28412.
- Kumar N, Khera R, Garg N. Atrial fibrillation associated hospitalizations in patients with end-stage renal disease in the United States, 2003–2012. Heart Rhythm 2016, 13: 2027-2033. PMID: 27374238, DOI: 10.1016/j.hrthm.2016.06.031.
- Khera R, Murad MH, Chandar AK, Dulai PS, Wang Z, Prokop LJ, Loomba R, Camilleri M, Singh S. Association of Pharmacological Treatments for Obesity With Weight Loss and Adverse Events: A Systematic Review and Meta-analysis. JAMA 2016, 315: 2424-2434. PMID: 27299618, PMCID: PMC5617638, DOI: 10.1001/jama.2016.7602.
- Kumar N, Khera R, Pandey A, Garg N. Racial Differences in Outcomes after Acute Ischemic Stroke Hospitalization in the United States. Journal Of Stroke And Cerebrovascular Diseases 2016, 25: 1970-1977. PMID: 27212273, DOI: 10.1016/j.jstrokecerebrovasdis.2016.03.049.
- Khera R, Girotra S. Response to “the Use of Mechanical Support Devices in Percutaneous Coronary Interventions: the Controversy?”. The American Journal Of Cardiology 2016, 120: e5. PMID: 27269587, DOI: 10.1016/j.amjcard.2016.05.001.
- Khera R, Girotra S. Mechanical Circulatory Support and Rationale for Future Research—Reply. JAMA Internal Medicine 2016, 176: 714-715. PMID: 27136338, DOI: 10.1001/jamainternmed.2016.0810.
- Kumar N, Venkatraman A, Pandey A, Khera R, Garg N. Weekend hospitalizations for acute aortic dissection have a higher risk of in-hospital mortality compared to weekday hospitalizations. International Journal Of Cardiology 2016, 214: 448-450. PMID: 27093682, DOI: 10.1016/j.ijcard.2016.03.187.
- Khera R, Girotra S. Response to “Higher mortality among males in takotsubo cardiomyopathy”. American Heart Journal 2016, 176: e3. PMID: 27264234, DOI: 10.1016/j.ahj.2016.03.010.
- Pandey A, Khera R, Kumar N, Golwala H, Girotra S, Fonarow GC. Use of Pulmonary Artery Catheterization in US Patients With Heart Failure, 2001-2012. JAMA Internal Medicine 2016, 176: 1-4. PMID: 26618346, PMCID: PMC4780342, DOI: 10.1001/jamainternmed.2015.6190.
- Jain S, Khera R, Suneja M, Gehlbach B, Kuperman E, Lopez F. Role of D-dimer Assays in the Diagnostic Evaluation of Pulmonary Embolism. The American Journal Of The Medical Sciences 2015, 350: 501-507. PMID: 25719981, DOI: 10.1097/maj.0000000000000405.
- Khera R, Light-McGroary K, Zahr F, Horwitz PA, Girotra S. Trends in hospitalization for takotsubo cardiomyopathy in the United States. American Heart Journal 2015, 172: 53-63. PMID: 26856216, PMCID: PMC4748175, DOI: 10.1016/j.ahj.2015.10.022.
- Singh S, Khera R, Allen AM, Murad MH, Loomba R. Comparative effectiveness of pharmacological interventions for nonalcoholic steatohepatitis: A systematic review and network meta‐analysis. Hepatology 2015, 62: 1417-1432. PMID: 26189925, DOI: 10.1002/hep.27999.
- Khera R, Cram P, Vaughan-Sarrazin M, Horwitz PA, Girotra S. Use of Mechanical Circulatory Support in Percutaneous Coronary Intervention in the United States. The American Journal Of Cardiology 2015, 117: 10-16. PMID: 26547292, PMCID: PMC4690753, DOI: 10.1016/j.amjcard.2015.10.005.
- Steyers CM, Khera R, Bhave P. Pacemaker Dependency after Cardiac Surgery: A Systematic Review of Current Evidence. PLOS ONE 2015, 10: e0140340. PMID: 26470027, PMCID: PMC4607414, DOI: 10.1371/journal.pone.0140340.
- Jain S, Khera R. Herpes zoster ophthalmicus complicated by encephalitis. Canadian Medical Association Journal 2015, 188: cmaj.150342. PMID: 26350907, PMCID: PMC4771550, DOI: 10.1503/cmaj.150342.
- Khera R, Cram P, Girotra S. Letter by Khera et al Regarding Article, “Impact of Annual Operator and Institutional Volume on Percutaneous Coronary Intervention Outcomes. Circulation 2015, 132: e35. PMID: 26240269, PMCID: PMC4617823, DOI: 10.1161/circulationaha.114.013342.
- Thirugnanasambandam N, Khera R, Wang H, Kukke SN, Hallett M. Distinct interneuronal networks influence excitability of the surround during movement initiation. Journal Of Neurophysiology 2015, 114: 1102-1108. PMID: 26041828, PMCID: PMC4588516, DOI: 10.1152/jn.00791.2014.
- Khera R, Cram P, Lu X, Vyas A, Gerke A, Rosenthal GE, Horwitz PA, Girotra S. Trends in the Use of Percutaneous Ventricular Assist Devices: Analysis of National Inpatient Sample Data, 2007 Through 2012. JAMA Internal Medicine 2015, 175: 941-950. PMID: 25822170, PMCID: PMC4780323, DOI: 10.1001/jamainternmed.2014.7856.
- Khera R, Vaughan-Sarrazin M, Rosenthal GE, Girotra S. Racial Disparities in Outcomes After Cardiac Surgery: the Role of Hospital Quality. Current Cardiology Reports 2015, 17: 29. PMID: 25894800, PMCID: PMC4780328, DOI: 10.1007/s11886-015-0587-7.
- Jain S, Khera R, Corrales–Medina V, Townsend RR, Chirinos JA. “Inflammation and arterial stiffness in humans”. Atherosclerosis 2014, 237: 381-390. PMID: 25463062, DOI: 10.1016/j.atherosclerosis.2014.09.011.
- Khera R, Jain S, Lodha R, Ramakrishnan S. Gender bias in child care and child health: global patterns. Archives Of Disease In Childhood 2013, 99: 369. PMID: 24344176, DOI: 10.1136/archdischild-2013-303889.
- Das N, Biswas B, Khera R. Membrane-Bound Complement Regulatory Proteins as Biomarkers and Potential Therapeutic Targets for SLE. Advances In Experimental Medicine And Biology 2012, 735: 55-81. PMID: 23402019, DOI: 10.1007/978-1-4614-4118-2_4.
- Ramakrishnan S, Khera R, Jain S, Saxena A, Kailash S, Karthikeyan G, Kothari SS, Juneja R, Bhargava B, Kalaivani M, Mehta M, Bahl VK, Airan B. Gender differences in the utilisation of surgery for congenital heart disease in India. Heart 2011, 97: 1920. PMID: 21653217, DOI: 10.1136/hrt.2011.224410.
- Khera R, Jain S, Kumar L, Thulkar S, Vijayraghwan M, Dawar R. Diffuse large B-cell lymphoma: experience from a tertiary care center in north India. Medical Oncology 2009, 27: 310-318. PMID: 19350421, DOI: 10.1007/s12032-009-9211-2.
- Khera R, Das N. Complement Receptor 1: Disease associations and therapeutic implications. Molecular Immunology 2008, 46: 761-772. PMID: 19004497, PMCID: PMC7125513, DOI: 10.1016/j.molimm.2008.09.026.