first name 2024/10/16 middle name2024/10/16 last name2024/10/16, MD/PhD
Biography
Peggy Myung, MD, PhD, is a Yale Medicine dermatopathologist, or skin pathologist, whose work focuses on identifying skin cancers, infections and other skin, hair and nail diseases.
“The possibility of making new discoveries and influencing the lives of people around me is what I love about my work,” says Dr. Myung. “I don't think we ever stop wanting to learn.” Dr. Myung is part of a research program that studies the skin’s built-in methods to regenerate tissue and suppress skin cancer growth. She also studies hair follicle development and regeneration in the laboratory.
“Our long-term goal is to develop novel treatments for hair loss and to prevent and treat non-melanoma skin cancer,” she says.
Titles
- Vice Chair of Research. Associate Professor of Dermatology and of Pathology.
Education & Training
- FellowshipYale University School of Medicine (2014)
- ResidencyUniversity Hospitals Case Medical Center (2012)
- ResidencyHospital of the University of Pennsylvania (2006)
- InternshipHospital of the University of Pennsylvania (2004)
- MD/PhDUniversity of Pennsylvania (2003)
Additional Information
- AB of Dermatology, Dermatopathology (2014)
- AB of Dermatology, Dermatology (2012)
- Jiang Y, Myung P. 676 Wnt and SHH interact to determine hair follicle dermal condensate fate. Journal Of Investigative Dermatology 2024, 144: s118. DOI: 10.1016/j.jid.2024.06.692.
- Lee S, Platt S, Lim C, Ito M, Myung P. The development of hair follicles and nail. Developmental Biology 2024, 513: 3-11. PMID: 38759942, DOI: 10.1016/j.ydbio.2024.05.010.
- Ko C, Gehlhausen J, Cohen J, Jiang Y, Myung P, Croskerry P. Cognitive Bias in the Patient Encounter: Part II. Debiasing using an adaptive toolbox. Journal Of The American Academy Of Dermatology 2024 PMID: 38588820, DOI: 10.1016/j.jaad.2024.02.061.
- Qu R, Cheng X, Sefik E, Stanley III J, Landa B, Strino F, Platt S, Garritano J, Odell I, Coifman R, Flavell R, Myung P, Kluger Y. Gene trajectory inference for single-cell data by optimal transport metrics. Nature Biotechnology 2024, 1-11. PMID: 38580861, DOI: 10.1038/s41587-024-02186-3.
- Echeandia-Francis C, Nock M, Myung P, Zubek A. Rapidly progressive subungual gray-brown melanonychia. JAAD Case Reports 2024, 44: 113-115. PMID: 38414828, PMCID: PMC10897537, DOI: 10.1016/j.jdcr.2024.01.013.
- Myung P, Ito M. Solving a molecular cryptogram for the human fingerprint. Cell 2023, 186: 899-901. PMID: 36868211, DOI: 10.1016/j.cell.2023.01.032.
- Myung P, Andl T, Atit R. The origins of skin diversity: lessons from dermal fibroblasts. Development 2022, 149 PMID: 36444877, PMCID: PMC10112899, DOI: 10.1242/dev.200298.
- Atzmony L, Ugwu N, Bercovitch LG, Robinson‐Bostom L, Ko CJ, Myung P, Choate KA. Segmental basaloid follicular hamartomas derive from a post‐zygotic SMO p.L412F pathogenic variant and express hair follicle development‐related proteins in a pattern that distinguish them from basal cell carcinomas. American Journal Of Medical Genetics Part A 2022, 188: 3525-3530. PMID: 35972041, PMCID: PMC9669121, DOI: 10.1002/ajmg.a.62951.
- Jiang Y, Myung P. 703 Tracing the proliferative dynamics of dermal papilla (DP) progenitors during adult hair follicle (HF) regeneration. Journal Of Investigative Dermatology 2022, 142: s121. DOI: 10.1016/j.jid.2022.05.715.
- Strickland G, Qu R, Gupta K, Jiang Y, Dong D, Saez C, Weng P, Taketo M, Klugar Y, Myung P. 704 Decomposing a deterministic path to hair follicle dermal niche formation: The intersection of two morphogen gradients. Journal Of Investigative Dermatology 2022, 142: s122. DOI: 10.1016/j.jid.2022.05.716.
- Jiang Y, Myung P. Wound Healing Induced Hair Follicle Regeneration. Stem Cell Biology And Regenerative Medicine 2022, 72: 277-290. DOI: 10.1007/978-3-030-98331-4_13.
- Qu R, Gupta K, Dong D, Jiang Y, Landa B, Saez C, Strickland G, Levinsohn J, Weng PL, Taketo MM, Kluger Y, Myung P. Decomposing a deterministic path to mesenchymal niche formation by two intersecting morphogen gradients. Developmental Cell 2022, 57: 1053-1067.e5. PMID: 35421372, PMCID: PMC9050909, DOI: 10.1016/j.devcel.2022.03.011.
- Jin S, Guerrero-Juarez CF, Zhang L, Chang I, Ramos R, Kuan CH, Myung P, Plikus MV, Nie Q. Inference and analysis of cell-cell communication using CellChat. Nature Communications 2021, 12: 1088. PMID: 33597522, PMCID: PMC7889871, DOI: 10.1038/s41467-021-21246-9.
- Chugh R, Proctor DD, Little A, Myung P, Cowper S, Imaeda S, Pashankar DS, Al-Bawardy B. Cutaneous Vasculitis After Ustekinumab Induction in Crohn’s Disease. Inflammatory Bowel Diseases 2020, 27: e30-e31. PMID: 33179735, DOI: 10.1093/ibd/izaa285.
- Gehlhausen JR, Myung P, Zubek A. Pink plaques on the face of an adolescent male. International Journal Of Dermatology 2020, 60: e217-e218. PMID: 33084046, DOI: 10.1111/ijd.15265.
- Panse G, Subtil A, McNiff JM, Glusac EJ, Ko CJ, Galan A, Myung P, Xu ML. Cutaneous Involvement in Plasma Cell Myeloma. American Journal Of Clinical Pathology 2020, 155: 106-116. PMID: 32885235, DOI: 10.1093/ajcp/aqaa122.
- Sun Q, Katehis I, Lee W, Mohri Y, Takeo M, Lim C, Xu X, Myung P, Atit R, Taketo M, Moubarak R, Schober M, Osman I, Gay D, Saur D, Nishimura E, Ito M. 664 Oncogenic melanocyte stem cells, driven by regenerative niche signals, give rise to heterogeneous melanoma resembling human melanoma. Journal Of Investigative Dermatology 2020, 140: s90. DOI: 10.1016/j.jid.2020.03.676.
- Olamiju B, Myung P, Grant M, Leventhal JS. Tender subcubcutaneous plaques in a patient with acute myeloid leukemia. International Journal Of Dermatology 2020, 60: 311-313. PMID: 32424815, DOI: 10.1111/ijd.14943.
- Eldirany SA, Myung P, Bunick CG. Ixekizumab-induced alopecia areata. JAAD Case Reports 2019, 6: 51-53. PMID: 31909139, PMCID: PMC6938813, DOI: 10.1016/j.jdcr.2019.10.012.
- Sun Q, Lee W, Mohri Y, Takeo M, Lim CH, Xu X, Myung P, Atit RP, Taketo MM, Moubarak RS, Schober M, Osman I, Gay DL, Saur D, Nishimura EK, Ito M. A novel mouse model demonstrates that oncogenic melanocyte stem cells engender melanoma resembling human disease. Nature Communications 2019, 10: 5023. PMID: 31685822, PMCID: PMC6828673, DOI: 10.1038/s41467-019-12733-1.
- Levinsohn J, Myung P. Putting Cell Competition under the Microscope. Developmental Cell 2019, 49: 823-824. PMID: 31211989, DOI: 10.1016/j.devcel.2019.05.040.
- Lim C, Sun Q, Ratti K, Lee S, Zheng Y, Takeo M, Lee W, Rabbani P, Plikus M, Cain J, Wang D, Watkins N, Millar S, Taketo M, Myung P, Cotsarelis G, Ito M. 942 Hedgehog stimulates hair follicle neogenesis by creating inductive dermis during murine skin wound healing. Journal Of Investigative Dermatology 2019, 139: s163. DOI: 10.1016/j.jid.2019.03.1018.
- Roy SF, Dong D, Myung P, McNiff JM. Multinucleate cell angiohistiocytoma: A clinicopathologic study of 62 cases and proposed diagnostic criteria. Journal Of Cutaneous Pathology 2019, 46: 563-569. PMID: 30927287, DOI: 10.1111/cup.13463.
- Gupta K, Levinsohn J, Linderman G, Chen D, Sun TY, Dong D, Taketo MM, Bosenberg M, Kluger Y, Choate K, Myung P. Single-Cell Analysis Reveals a Hair Follicle Dermal Niche Molecular Differentiation Trajectory that Begins Prior to Morphogenesis. Developmental Cell 2018, 48: 17-31.e6. PMID: 30595533, PMCID: PMC6361530, DOI: 10.1016/j.devcel.2018.11.032.
- Lim CH, Sun Q, Ratti K, Lee SH, Zheng Y, Takeo M, Lee W, Rabbani P, Plikus MV, Cain JE, Wang DH, Watkins DN, Millar S, Taketo MM, Myung P, Cotsarelis G, Ito M. Hedgehog stimulates hair follicle neogenesis by creating inductive dermis during murine skin wound healing. Nature Communications 2018, 9: 4903. PMID: 30464171, PMCID: PMC6249328, DOI: 10.1038/s41467-018-07142-9.
- Ko CJ, Myung P, Leffell DJ, Bourdon JC. Cutaneous immunohistochemical staining pattern of p53β isoforms. Journal Of Clinical Pathology 2018, 71: 1120. PMID: 30305316, DOI: 10.1136/jclinpath-2018-205098.
- Sun Q, Lee W, Takeo M, Lim C, Xu X, Moubarak R, Myung P, Taketo M, Osman I, Nishimura E, Ito M. 1379 Cell of origin contributes to the melanoma diversity. Journal Of Investigative Dermatology 2018, 138: s234. DOI: 10.1016/j.jid.2018.03.1396.
- Sun Q, Rabbani P, Takeo M, Lee SH, Lim CH, Noel ES, Taketo MM, Myung P, Millar S, Ito M. Dissecting Wnt Signaling for Melanocyte Regulation during Wound Healing. Journal Of Investigative Dermatology 2018, 138: 1591-1600. PMID: 29428355, PMCID: PMC6019608, DOI: 10.1016/j.jid.2018.01.030.
- Hamburg-Shields E, Myung P, Cowper S. Cutaneous Fibrosis and Normal Wound Healing. 2017, 577-600. DOI: 10.1007/978-3-319-29785-9_32.
- Neckman JP, Kim J, Mathur M, Myung P, Girardi M. Diverse cutaneous manifestations of Erdheim-Chester disease in a woman with a history of Langerhans cell histiocytosis. JAAD Case Reports 2016, 2: 128-131. PMID: 27051852, PMCID: PMC4810280, DOI: 10.1016/j.jdcr.2015.10.010.
- Xin T, Greco V, Myung P. Hardwiring Stem Cell Communication through Tissue Structure. Cell 2016, 164: 1212-1225. PMID: 26967287, PMCID: PMC4805424, DOI: 10.1016/j.cell.2016.02.041.
- Myung P, Greco V. Stem Cells Show Parental Control. Cell 2015, 162: 476-477. PMID: 26232219, DOI: 10.1016/j.cell.2015.06.030.
- Mesa KR, Rompolas P, Zito G, Myung P, Sun TY, Brown S, Gonzalez DG, Blagoev KB, Haberman AM, Greco V. Niche-induced cell death and epithelial phagocytosis regulate hair follicle stem cell pool. Nature 2015, 522: 94-97. PMID: 25849774, PMCID: PMC4457634, DOI: 10.1038/nature14306.
- Deschene ER, Myung P, Rompolas P, Zito G, Sun TY, Taketo MM, Saotome I, Greco V. β-Catenin Activation Regulates Tissue Growth Non–Cell Autonomously in the Hair Stem Cell Niche. Science 2014, 343: 1353-1356. PMID: 24653033, PMCID: PMC4096864, DOI: 10.1126/science.1248373.
- Myung PS, Takeo M, Ito M, Atit RP. Epithelial Wnt Ligand Secretion Is Required for Adult Hair Follicle Growth and Regeneration. Journal Of Investigative Dermatology 2012, 133: 31-41. PMID: 22810306, PMCID: PMC3479363, DOI: 10.1038/jid.2012.230.
- Myung P, Ito M. Dissecting the bulge in hair regeneration. Journal Of Clinical Investigation 2012, 122: 448-454. PMID: 22293183, PMCID: PMC3266778, DOI: 10.1172/jci57414.
- Rabbani P, Takeo M, Chou W, Myung P, Bosenberg M, Chin L, Taketo MM, Ito M. Coordinated Activation of Wnt in Epithelial and Melanocyte Stem Cells Initiates Pigmented Hair Regeneration. Cell 2011, 145: 941-955. PMID: 21663796, PMCID: PMC3962257, DOI: 10.1016/j.cell.2011.05.004.
- Myung P, Andl T, Ito M. Defining the hair follicle stem cell (Part II). Journal Of Cutaneous Pathology 2009, 36: 1134-1137. PMID: 19712246, DOI: 10.1111/j.1600-0560.2009.01412.x.
- Myung P, Andl T, Ito M. Defining the hair follicle stem cell (Part I). Journal Of Cutaneous Pathology 2009, 36: 1031-1034. PMID: 19674210, DOI: 10.1111/j.1600-0560.2009.01396.x.
- Myung PS, Kundu M, Abboud SK. Eosinophilic Granuloma Manifesting as Painless Cervical Lymphadenopathy in a Patient Positive for Human Immunodeficiency Virus 1. JAMA Otolaryngology - Head & Neck Surgery 2008, 134: 203-205. PMID: 18283165, DOI: 10.1001/archoto.2007.14.
- Singer AL, Bunnell SC, Obstfeld AE, Jordan MS, Wu JN, Myung PS, Samelson LE, Koretzky GA. Roles of the Proline-rich Domain in SLP-76 Subcellular Localization and T Cell Function* [boxs]. Journal Of Biological Chemistry 2004, 279: 15481-15490. PMID: 14722089, DOI: 10.1074/jbc.m313339200.
- Nichols KE, Haines K, Myung PS, Newbrough S, Myers E, Jumaa H, Shedlock DJ, Shen H, Koretzky GA. Macrophage activation and Fcγ receptor-mediated signaling do not require expression of the SLP-76 and SLP-65 adaptors. Journal Of Leukocyte Biology 2003, 75: 541-552. PMID: 14694181, DOI: 10.1189/jlb.0703312.
- Singer A, Bunnell S, Obstfeld A, Jordan M, Wu J, Myung P, Samelson L, Koretzky G. Inhibition of T cell activation through interruption of adaptor protein associations. Journal Of Surgical Research 2003, 114: 271. DOI: 10.1016/j.jss.2003.08.227.
- Singer A, Jordan M, Judd B, Myung P, Newbrough S, Nichols K, Olenchock B, Peterson E, Wu J, Zhong X, Koretzky G. Signaling Via the T Cell Receptor. Science Signaling 2003, 2003 DOI: 10.1126/stke.2003.194.cm7.
- Judd BA, Myung PS, Obergfell A, Myers EE, Cheng AM, Watson SP, Pear WS, Allman D, Shattil SJ, Koretzky GA. Differential Requirement for LAT and SLP-76 in GPVI versus T Cell Receptor Signaling. Journal Of Experimental Medicine 2002, 195: 705-717. PMID: 11901197, PMCID: PMC2193740, DOI: 10.1084/jem.20011583.
- Myung P, Derimanov G, Jordan M, Punt J, Liu Q, Judd B, Meyers E, Sigmund C, Freedman B, Koretzky G. Differential Requirement for SLP-76 Domains in T Cell Development and Function. Immunity 2001, 15: 1011-1026. PMID: 11754821, DOI: 10.1016/s1074-7613(01)00253-9.
- Koretzky G, Myung P. Positive and negative regulation of t-cell activation by adaptor proteins. Nature Reviews Immunology 2001, 1: 95-107. PMID: 11905825, DOI: 10.1038/35100523.
- Peterson E, Woods M, Dmowski S, Derimanov G, Jordan M, Wu J, Myung P, Liu Q, Pribila J, Freedman B, Shimizu Y, Koretzky G. Coupling of the TCR to Integrin Activation by SLAP-130/Fyb. Science 2001, 293: 2263-2265. PMID: 11567141, DOI: 10.1126/science.1063486.
- Allman D, Karnell F, Punt J, Bakkour S, Xu L, Myung P, Koretzky G, Pui J, Aster J, Pear W. Separation of Notch1 Promoted Lineage Commitment and Expansion/Transformation in Developing T Cells. Journal Of Experimental Medicine 2001, 194: 99-106. PMID: 11435476, PMCID: PMC2193437, DOI: 10.1084/jem.194.1.99.
- Izon D, Punt J, Xu L, Karnell F, Allman D, Myung P, Boerth N, Pui J, Koretzky G, Pear W. Notch1 Regulates Maturation of CD4+ and CD8+ Thymocytes by Modulating TCR Signal Strength. Immunity 2001, 14: 253-264. PMID: 11290335, DOI: 10.1016/s1074-7613(01)00107-8.
- Judd B, Myung P, Leng L, Obergfell A, Pear W, Shattil S, Koretzky G. Hematopoietic reconstitution of SLP-76 corrects hemostasis and platelet signaling through αIIbβ3 and collagen receptors. Proceedings Of The National Academy Of Sciences Of The United States Of America 2000, 97: 12056-12061. PMID: 11050236, PMCID: PMC17293, DOI: 10.1073/pnas.97.22.12056.
- Myung P, Boerthe N, Koretzky G. Adapter proteins in lymphocyte antigen-receptor signaling. Current Opinion In Immunology 2000, 12: 256-266. PMID: 10781404, DOI: 10.1016/s0952-7915(00)00085-6.
- Myung PS, Clements JL, White DW, Malik ZA, Cowdery JS, Allen LH, Harty JT, Kusner DJ, Koretzky GA. In vitro and in vivo macrophage function can occur independently of SLP-76. International Immunology 2000, 12: 887-897. PMID: 10837416, DOI: 10.1093/intimm/12.6.887.
- Cowdery J, Boerth N, Norian L, Myung P, Koretzky G. Differential regulation of the IL-12 p40 promoter and of p40 secretion by CpG DNA and lipopolysaccharide. The Journal Of Immunology 1999, 162: 6770-5. PMID: 10352297, DOI: 10.4049/jimmunol.162.11.6770.
- Sun P, Enslen H, Myung PS, Maurer RA. Differential activation of CREB by Ca2+/calmodulin-dependent protein kinases type II and type IV involves phosphorylation of a site that negatively regulates activity. Genes & Development 1994, 8: 2527-39. PMID: 7958915, DOI: 10.1101/gad.8.21.2527.
Biography
Peggy Myung, MD, PhD, is a Yale Medicine dermatopathologist, or skin pathologist, whose work focuses on identifying skin cancers, infections and other skin, hair and nail diseases.
“The possibility of making new discoveries and influencing the lives of people around me is what I love about my work,” says Dr. Myung. “I don't think we ever stop wanting to learn.” Dr. Myung is part of a research program that studies the skin’s built-in methods to regenerate tissue and suppress skin cancer growth. She also studies hair follicle development and regeneration in the laboratory.
“Our long-term goal is to develop novel treatments for hair loss and to prevent and treat non-melanoma skin cancer,” she says.
Titles
- Vice Chair of Research. Associate Professor of Dermatology and of Pathology.
Education & Training
- FellowshipYale University School of Medicine (2014)
- ResidencyUniversity Hospitals Case Medical Center (2012)
- ResidencyHospital of the University of Pennsylvania (2006)
- InternshipHospital of the University of Pennsylvania (2004)
- MD/PhDUniversity of Pennsylvania (2003)
Additional Information
- AB of Dermatology, Dermatopathology (2014)
- AB of Dermatology, Dermatology (2012)
- Jiang Y, Myung P. 676 Wnt and SHH interact to determine hair follicle dermal condensate fate. Journal Of Investigative Dermatology 2024, 144: s118. DOI: 10.1016/j.jid.2024.06.692.
- Lee S, Platt S, Lim C, Ito M, Myung P. The development of hair follicles and nail. Developmental Biology 2024, 513: 3-11. PMID: 38759942, DOI: 10.1016/j.ydbio.2024.05.010.
- Ko C, Gehlhausen J, Cohen J, Jiang Y, Myung P, Croskerry P. Cognitive Bias in the Patient Encounter: Part II. Debiasing using an adaptive toolbox. Journal Of The American Academy Of Dermatology 2024 PMID: 38588820, DOI: 10.1016/j.jaad.2024.02.061.
- Qu R, Cheng X, Sefik E, Stanley III J, Landa B, Strino F, Platt S, Garritano J, Odell I, Coifman R, Flavell R, Myung P, Kluger Y. Gene trajectory inference for single-cell data by optimal transport metrics. Nature Biotechnology 2024, 1-11. PMID: 38580861, DOI: 10.1038/s41587-024-02186-3.
- Echeandia-Francis C, Nock M, Myung P, Zubek A. Rapidly progressive subungual gray-brown melanonychia. JAAD Case Reports 2024, 44: 113-115. PMID: 38414828, PMCID: PMC10897537, DOI: 10.1016/j.jdcr.2024.01.013.
- Myung P, Ito M. Solving a molecular cryptogram for the human fingerprint. Cell 2023, 186: 899-901. PMID: 36868211, DOI: 10.1016/j.cell.2023.01.032.
- Myung P, Andl T, Atit R. The origins of skin diversity: lessons from dermal fibroblasts. Development 2022, 149 PMID: 36444877, PMCID: PMC10112899, DOI: 10.1242/dev.200298.
- Atzmony L, Ugwu N, Bercovitch LG, Robinson‐Bostom L, Ko CJ, Myung P, Choate KA. Segmental basaloid follicular hamartomas derive from a post‐zygotic SMO p.L412F pathogenic variant and express hair follicle development‐related proteins in a pattern that distinguish them from basal cell carcinomas. American Journal Of Medical Genetics Part A 2022, 188: 3525-3530. PMID: 35972041, PMCID: PMC9669121, DOI: 10.1002/ajmg.a.62951.
- Jiang Y, Myung P. 703 Tracing the proliferative dynamics of dermal papilla (DP) progenitors during adult hair follicle (HF) regeneration. Journal Of Investigative Dermatology 2022, 142: s121. DOI: 10.1016/j.jid.2022.05.715.
- Strickland G, Qu R, Gupta K, Jiang Y, Dong D, Saez C, Weng P, Taketo M, Klugar Y, Myung P. 704 Decomposing a deterministic path to hair follicle dermal niche formation: The intersection of two morphogen gradients. Journal Of Investigative Dermatology 2022, 142: s122. DOI: 10.1016/j.jid.2022.05.716.
- Jiang Y, Myung P. Wound Healing Induced Hair Follicle Regeneration. Stem Cell Biology And Regenerative Medicine 2022, 72: 277-290. DOI: 10.1007/978-3-030-98331-4_13.
- Qu R, Gupta K, Dong D, Jiang Y, Landa B, Saez C, Strickland G, Levinsohn J, Weng PL, Taketo MM, Kluger Y, Myung P. Decomposing a deterministic path to mesenchymal niche formation by two intersecting morphogen gradients. Developmental Cell 2022, 57: 1053-1067.e5. PMID: 35421372, PMCID: PMC9050909, DOI: 10.1016/j.devcel.2022.03.011.
- Jin S, Guerrero-Juarez CF, Zhang L, Chang I, Ramos R, Kuan CH, Myung P, Plikus MV, Nie Q. Inference and analysis of cell-cell communication using CellChat. Nature Communications 2021, 12: 1088. PMID: 33597522, PMCID: PMC7889871, DOI: 10.1038/s41467-021-21246-9.
- Chugh R, Proctor DD, Little A, Myung P, Cowper S, Imaeda S, Pashankar DS, Al-Bawardy B. Cutaneous Vasculitis After Ustekinumab Induction in Crohn’s Disease. Inflammatory Bowel Diseases 2020, 27: e30-e31. PMID: 33179735, DOI: 10.1093/ibd/izaa285.
- Gehlhausen JR, Myung P, Zubek A. Pink plaques on the face of an adolescent male. International Journal Of Dermatology 2020, 60: e217-e218. PMID: 33084046, DOI: 10.1111/ijd.15265.
- Panse G, Subtil A, McNiff JM, Glusac EJ, Ko CJ, Galan A, Myung P, Xu ML. Cutaneous Involvement in Plasma Cell Myeloma. American Journal Of Clinical Pathology 2020, 155: 106-116. PMID: 32885235, DOI: 10.1093/ajcp/aqaa122.
- Sun Q, Katehis I, Lee W, Mohri Y, Takeo M, Lim C, Xu X, Myung P, Atit R, Taketo M, Moubarak R, Schober M, Osman I, Gay D, Saur D, Nishimura E, Ito M. 664 Oncogenic melanocyte stem cells, driven by regenerative niche signals, give rise to heterogeneous melanoma resembling human melanoma. Journal Of Investigative Dermatology 2020, 140: s90. DOI: 10.1016/j.jid.2020.03.676.
- Olamiju B, Myung P, Grant M, Leventhal JS. Tender subcubcutaneous plaques in a patient with acute myeloid leukemia. International Journal Of Dermatology 2020, 60: 311-313. PMID: 32424815, DOI: 10.1111/ijd.14943.
- Eldirany SA, Myung P, Bunick CG. Ixekizumab-induced alopecia areata. JAAD Case Reports 2019, 6: 51-53. PMID: 31909139, PMCID: PMC6938813, DOI: 10.1016/j.jdcr.2019.10.012.
- Sun Q, Lee W, Mohri Y, Takeo M, Lim CH, Xu X, Myung P, Atit RP, Taketo MM, Moubarak RS, Schober M, Osman I, Gay DL, Saur D, Nishimura EK, Ito M. A novel mouse model demonstrates that oncogenic melanocyte stem cells engender melanoma resembling human disease. Nature Communications 2019, 10: 5023. PMID: 31685822, PMCID: PMC6828673, DOI: 10.1038/s41467-019-12733-1.
- Levinsohn J, Myung P. Putting Cell Competition under the Microscope. Developmental Cell 2019, 49: 823-824. PMID: 31211989, DOI: 10.1016/j.devcel.2019.05.040.
- Lim C, Sun Q, Ratti K, Lee S, Zheng Y, Takeo M, Lee W, Rabbani P, Plikus M, Cain J, Wang D, Watkins N, Millar S, Taketo M, Myung P, Cotsarelis G, Ito M. 942 Hedgehog stimulates hair follicle neogenesis by creating inductive dermis during murine skin wound healing. Journal Of Investigative Dermatology 2019, 139: s163. DOI: 10.1016/j.jid.2019.03.1018.
- Roy SF, Dong D, Myung P, McNiff JM. Multinucleate cell angiohistiocytoma: A clinicopathologic study of 62 cases and proposed diagnostic criteria. Journal Of Cutaneous Pathology 2019, 46: 563-569. PMID: 30927287, DOI: 10.1111/cup.13463.
- Gupta K, Levinsohn J, Linderman G, Chen D, Sun TY, Dong D, Taketo MM, Bosenberg M, Kluger Y, Choate K, Myung P. Single-Cell Analysis Reveals a Hair Follicle Dermal Niche Molecular Differentiation Trajectory that Begins Prior to Morphogenesis. Developmental Cell 2018, 48: 17-31.e6. PMID: 30595533, PMCID: PMC6361530, DOI: 10.1016/j.devcel.2018.11.032.
- Lim CH, Sun Q, Ratti K, Lee SH, Zheng Y, Takeo M, Lee W, Rabbani P, Plikus MV, Cain JE, Wang DH, Watkins DN, Millar S, Taketo MM, Myung P, Cotsarelis G, Ito M. Hedgehog stimulates hair follicle neogenesis by creating inductive dermis during murine skin wound healing. Nature Communications 2018, 9: 4903. PMID: 30464171, PMCID: PMC6249328, DOI: 10.1038/s41467-018-07142-9.
- Ko CJ, Myung P, Leffell DJ, Bourdon JC. Cutaneous immunohistochemical staining pattern of p53β isoforms. Journal Of Clinical Pathology 2018, 71: 1120. PMID: 30305316, DOI: 10.1136/jclinpath-2018-205098.
- Sun Q, Lee W, Takeo M, Lim C, Xu X, Moubarak R, Myung P, Taketo M, Osman I, Nishimura E, Ito M. 1379 Cell of origin contributes to the melanoma diversity. Journal Of Investigative Dermatology 2018, 138: s234. DOI: 10.1016/j.jid.2018.03.1396.
- Sun Q, Rabbani P, Takeo M, Lee SH, Lim CH, Noel ES, Taketo MM, Myung P, Millar S, Ito M. Dissecting Wnt Signaling for Melanocyte Regulation during Wound Healing. Journal Of Investigative Dermatology 2018, 138: 1591-1600. PMID: 29428355, PMCID: PMC6019608, DOI: 10.1016/j.jid.2018.01.030.
- Hamburg-Shields E, Myung P, Cowper S. Cutaneous Fibrosis and Normal Wound Healing. 2017, 577-600. DOI: 10.1007/978-3-319-29785-9_32.
- Neckman JP, Kim J, Mathur M, Myung P, Girardi M. Diverse cutaneous manifestations of Erdheim-Chester disease in a woman with a history of Langerhans cell histiocytosis. JAAD Case Reports 2016, 2: 128-131. PMID: 27051852, PMCID: PMC4810280, DOI: 10.1016/j.jdcr.2015.10.010.
- Xin T, Greco V, Myung P. Hardwiring Stem Cell Communication through Tissue Structure. Cell 2016, 164: 1212-1225. PMID: 26967287, PMCID: PMC4805424, DOI: 10.1016/j.cell.2016.02.041.
- Myung P, Greco V. Stem Cells Show Parental Control. Cell 2015, 162: 476-477. PMID: 26232219, DOI: 10.1016/j.cell.2015.06.030.
- Mesa KR, Rompolas P, Zito G, Myung P, Sun TY, Brown S, Gonzalez DG, Blagoev KB, Haberman AM, Greco V. Niche-induced cell death and epithelial phagocytosis regulate hair follicle stem cell pool. Nature 2015, 522: 94-97. PMID: 25849774, PMCID: PMC4457634, DOI: 10.1038/nature14306.
- Deschene ER, Myung P, Rompolas P, Zito G, Sun TY, Taketo MM, Saotome I, Greco V. β-Catenin Activation Regulates Tissue Growth Non–Cell Autonomously in the Hair Stem Cell Niche. Science 2014, 343: 1353-1356. PMID: 24653033, PMCID: PMC4096864, DOI: 10.1126/science.1248373.
- Myung PS, Takeo M, Ito M, Atit RP. Epithelial Wnt Ligand Secretion Is Required for Adult Hair Follicle Growth and Regeneration. Journal Of Investigative Dermatology 2012, 133: 31-41. PMID: 22810306, PMCID: PMC3479363, DOI: 10.1038/jid.2012.230.
- Myung P, Ito M. Dissecting the bulge in hair regeneration. Journal Of Clinical Investigation 2012, 122: 448-454. PMID: 22293183, PMCID: PMC3266778, DOI: 10.1172/jci57414.
- Rabbani P, Takeo M, Chou W, Myung P, Bosenberg M, Chin L, Taketo MM, Ito M. Coordinated Activation of Wnt in Epithelial and Melanocyte Stem Cells Initiates Pigmented Hair Regeneration. Cell 2011, 145: 941-955. PMID: 21663796, PMCID: PMC3962257, DOI: 10.1016/j.cell.2011.05.004.
- Myung P, Andl T, Ito M. Defining the hair follicle stem cell (Part II). Journal Of Cutaneous Pathology 2009, 36: 1134-1137. PMID: 19712246, DOI: 10.1111/j.1600-0560.2009.01412.x.
- Myung P, Andl T, Ito M. Defining the hair follicle stem cell (Part I). Journal Of Cutaneous Pathology 2009, 36: 1031-1034. PMID: 19674210, DOI: 10.1111/j.1600-0560.2009.01396.x.
- Myung PS, Kundu M, Abboud SK. Eosinophilic Granuloma Manifesting as Painless Cervical Lymphadenopathy in a Patient Positive for Human Immunodeficiency Virus 1. JAMA Otolaryngology - Head & Neck Surgery 2008, 134: 203-205. PMID: 18283165, DOI: 10.1001/archoto.2007.14.
- Singer AL, Bunnell SC, Obstfeld AE, Jordan MS, Wu JN, Myung PS, Samelson LE, Koretzky GA. Roles of the Proline-rich Domain in SLP-76 Subcellular Localization and T Cell Function* [boxs]. Journal Of Biological Chemistry 2004, 279: 15481-15490. PMID: 14722089, DOI: 10.1074/jbc.m313339200.
- Nichols KE, Haines K, Myung PS, Newbrough S, Myers E, Jumaa H, Shedlock DJ, Shen H, Koretzky GA. Macrophage activation and Fcγ receptor-mediated signaling do not require expression of the SLP-76 and SLP-65 adaptors. Journal Of Leukocyte Biology 2003, 75: 541-552. PMID: 14694181, DOI: 10.1189/jlb.0703312.
- Singer A, Bunnell S, Obstfeld A, Jordan M, Wu J, Myung P, Samelson L, Koretzky G. Inhibition of T cell activation through interruption of adaptor protein associations. Journal Of Surgical Research 2003, 114: 271. DOI: 10.1016/j.jss.2003.08.227.
- Singer A, Jordan M, Judd B, Myung P, Newbrough S, Nichols K, Olenchock B, Peterson E, Wu J, Zhong X, Koretzky G. Signaling Via the T Cell Receptor. Science Signaling 2003, 2003 DOI: 10.1126/stke.2003.194.cm7.
- Judd BA, Myung PS, Obergfell A, Myers EE, Cheng AM, Watson SP, Pear WS, Allman D, Shattil SJ, Koretzky GA. Differential Requirement for LAT and SLP-76 in GPVI versus T Cell Receptor Signaling. Journal Of Experimental Medicine 2002, 195: 705-717. PMID: 11901197, PMCID: PMC2193740, DOI: 10.1084/jem.20011583.
- Myung P, Derimanov G, Jordan M, Punt J, Liu Q, Judd B, Meyers E, Sigmund C, Freedman B, Koretzky G. Differential Requirement for SLP-76 Domains in T Cell Development and Function. Immunity 2001, 15: 1011-1026. PMID: 11754821, DOI: 10.1016/s1074-7613(01)00253-9.
- Koretzky G, Myung P. Positive and negative regulation of t-cell activation by adaptor proteins. Nature Reviews Immunology 2001, 1: 95-107. PMID: 11905825, DOI: 10.1038/35100523.
- Peterson E, Woods M, Dmowski S, Derimanov G, Jordan M, Wu J, Myung P, Liu Q, Pribila J, Freedman B, Shimizu Y, Koretzky G. Coupling of the TCR to Integrin Activation by SLAP-130/Fyb. Science 2001, 293: 2263-2265. PMID: 11567141, DOI: 10.1126/science.1063486.
- Allman D, Karnell F, Punt J, Bakkour S, Xu L, Myung P, Koretzky G, Pui J, Aster J, Pear W. Separation of Notch1 Promoted Lineage Commitment and Expansion/Transformation in Developing T Cells. Journal Of Experimental Medicine 2001, 194: 99-106. PMID: 11435476, PMCID: PMC2193437, DOI: 10.1084/jem.194.1.99.
- Izon D, Punt J, Xu L, Karnell F, Allman D, Myung P, Boerth N, Pui J, Koretzky G, Pear W. Notch1 Regulates Maturation of CD4+ and CD8+ Thymocytes by Modulating TCR Signal Strength. Immunity 2001, 14: 253-264. PMID: 11290335, DOI: 10.1016/s1074-7613(01)00107-8.
- Judd B, Myung P, Leng L, Obergfell A, Pear W, Shattil S, Koretzky G. Hematopoietic reconstitution of SLP-76 corrects hemostasis and platelet signaling through αIIbβ3 and collagen receptors. Proceedings Of The National Academy Of Sciences Of The United States Of America 2000, 97: 12056-12061. PMID: 11050236, PMCID: PMC17293, DOI: 10.1073/pnas.97.22.12056.
- Myung P, Boerthe N, Koretzky G. Adapter proteins in lymphocyte antigen-receptor signaling. Current Opinion In Immunology 2000, 12: 256-266. PMID: 10781404, DOI: 10.1016/s0952-7915(00)00085-6.
- Myung PS, Clements JL, White DW, Malik ZA, Cowdery JS, Allen LH, Harty JT, Kusner DJ, Koretzky GA. In vitro and in vivo macrophage function can occur independently of SLP-76. International Immunology 2000, 12: 887-897. PMID: 10837416, DOI: 10.1093/intimm/12.6.887.
- Cowdery J, Boerth N, Norian L, Myung P, Koretzky G. Differential regulation of the IL-12 p40 promoter and of p40 secretion by CpG DNA and lipopolysaccharide. The Journal Of Immunology 1999, 162: 6770-5. PMID: 10352297, DOI: 10.4049/jimmunol.162.11.6770.
- Sun P, Enslen H, Myung PS, Maurer RA. Differential activation of CREB by Ca2+/calmodulin-dependent protein kinases type II and type IV involves phosphorylation of a site that negatively regulates activity. Genes & Development 1994, 8: 2527-39. PMID: 7958915, DOI: 10.1101/gad.8.21.2527.