Nishant K. Mishra, MD, PhD, FRCP, FAHA
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Biography
Nishant Kumar Mishra, MBBS, PhD, MD, is a neurologist who specializes in vascular neurology and stroke. “My goal is to make a positive impact in the lives of stroke patients, not only by offering the best care, but also by advancing the field through clinical research and novel discoveries,” he says.
Dr. Mishra says he became a doctor because he wanted to be of service to people. “We deal with stroke on a daily basis, but our patients are dealing with it for the first time,” he says. Often stroke patients are figuring out how to manage cognitive issues, changes in mood, or questions about why this happened to them. “So, I try to offer them a good deal of time to get a sense of exactly what is going on with them, and then put myself in their shoes,” Dr. Mishra says. “If I wasn’t the doctor, how would I expect to be treated?”
Before he came to Yale in 2021, Dr. Mishra worked at several major stroke centers and neurology institutes around the world, and was a clinical scientist at the Food and Drug Administration. He made significant contributions to the field through his doctoral work, informing whether the exclusion criteria proposed by drug authorities for the treatment of ischemic stroke patients were meaningful and should be followed.
He also pursues clinical research that spans the breadth of stroke care, including acute intervention, prevention, and post-stroke recovery. “I’ve spent a large part of my life not only improving the outcomes of patients by optimizing their medical care, but also though research in collaborative efforts with my colleagues, and that has contributed to significant changes to the way we treat patients, which has really encouraged me to keep going,” he says.
Titles
- Assistant Professor of Neurology
- Affiliated Faculty, Yale Institute of Global Health
- Stroke Director, U.S. Department of Veterans Affairs, West Haven VA Medical Center
Education & Training
- Vascular Neurology ACGME FellowUCLA (2021)
- NIH StrokeNet FellowUCLA (Mentors: J. Saver, MD; D.S. Liebeskind, MD) (2021)
- MDThe University of The State of New York, By Conferral (2020)
- Neurology ResidentMt. Sinai Hospital, Icahn School of Medicine at Mt. Sinai (2020)
- Neurology ResidentTulane University (2018)
- InternshipTulane University (2017)
- ORISE Medical ScientistUS Food and Drug Administration (2016)
- Postdoctoral Fellow in Vascular NeurologyStanford University (Mentors: G. Albers, MD; M. Lansberg, MD) (2014)
- PhDUniversity of Glasgow, Medicine and Therapeutics (Mentor: K.R. Lees, MD, FRCP) (2012)
- Visiting ResearcherUT Houston (Mentors: J. Grotta, MD; Collaborator: TA Kent, MD; P Mandava, MD) (2011)
- Visiting ESO researcherKarolinska University (Collaborator: N. Wahlgren, MD) (2009)
- ESKAS Clinical FellowUniversity of Lausanne, CHUV (Mentors: A. Carota, MD; J.M. Annoni, MD) (2008)
- MBBSMaharashtra University of Health Sciences, Nashik, India (2005)
Languages Spoken
- English
- हिन्दी (Hindi)
Additional Information
- Fellow of Royal College of Physician: Royal College of Physician, Glasgow (2023)
- StrokeNet Fellow, 2020-2021: NIH/ UCLA (2020)
- R25 NIH award: National Institutes of Health (2020)
- Leon Levy Foundation award: Leon Levy Foundation (2020)
- Exceptional Reviewer: Annals of Internal Medicine (2019)
- Exceptional Reviewer: Annals of Internal Medicine (2017)
- ORISE award: OWH/ US FDA/ Oak Ridge Institute for Science and Education (2015)
- Jim Gatheral Scholarship, UT Houston (Mentor: Dr. J Grotta): University of Glasgow, Scotland (2011)
- Department to Department SITS-ISTR collaboration award, Karolinska University, Sweden: European Stroke Organisation (2010)
- Overseas Research Studentship Award (ORSAS), University of Glasgow, Scotland, UK: UK Secretary of State for Education and Science (ORSAS) (2009)
- United Kingdom Research and Innovation/ Medical Research Council (UKRI/MRC) (2023 - Present): Grant reviewer
- American Indian Neurologist Association (2023 - Present): Executive Committee Member; https://www.4aina.com/Board
- All India Institute of Medical Sciences, New Delhi, India (2022 - Present): External examiner of a Ph.D. in Neurology thesis; Ref: AIIMS/ExamSec/Ph.D/12-04/2022
- Association of Indian Neurologist Association (2022 - Present): Member
- American Heart Association (2022 - Present): FAHA
- Neurology (Green Journal) (2022 - Present): Editorial Board Member
- Clinical Neurology and Neurosurgery (2022 - Present): Reviewer
- Alzheimers Disease and Associated Disorders (2022 - Present): Reviewer
- BMJ Surgery, Interventions, and Health Technologies (2022 - Present): Reviewer
- International Post-Stroke Epilepsy Research Consortium (IPSERC) (2021 - Present): Convenor, IPSERC.
- Mishra NK, Engel J, Liebeskind DS, Sharma VK, Hirsch LJ, Kasner SE, French JA, Devinsky O, Friedman A, Dawson J, Quinn TJ, Selim M, de Havenon A, Yasuda CL, Cendes F, Benninger F, Zaveri HP, Burneo JG, Srivastava P, Singh M, Bhatia R, Vishnu VY, Bentes C, Ferro J, Weiss S, Sivaraju A, Kim JA, Galovic M, Gilmore EJ, Pitkänen A, Davis K, Sansing LH, Sheth KN, Paz JT, Singh A, Sheth S, Worrall BB, Grotta JC, Casillas-Espinos PM, Chen Z, Nicolo JP, Yan B, Kwan P, Consortium F. International Post Stroke Epilepsy Research Consortium (IPSERC): A consortium to accelerate discoveries in preventing epileptogenesis after stroke. Epilepsy & Behavior 2021, 127: 108502. PMID: 34968775, DOI: 10.1016/j.yebeh.2021.108502.
- Misra S, Quinn T, Falcone G, Sharma V, de Havenon A, Zhao Y, Eldem E, French J, Yasuda C, Dawson J, Liebeskind D, Kwan P, Mishra N. Impact of genetic polymorphisms on the risk of epilepsy amongst patients with acute brain injury: A systematic review. European Journal Of Neurology 2023, 30: 1791-1800. PMID: 36912749, DOI: 10.1111/ene.15777.
- Misra S, Khan E, Lam T, Mazumder R, Gururangan K, Hickman L, Goswami V, Funaro M, Eldem E, Sansing L, Sico J, Quinn T, Liebeskind D, Montaner J, Kwan P, Mishra N. Common Pathways of Epileptogenesis in Patients With Epilepsy Post–Brain Injury. Neurology 2023, 101: e2243-e2256. PMID: 37550071, PMCID: PMC10727219, DOI: 10.1212/wnl.0000000000207749.
- Mishra N, Liebeskind D. Artificial Intelligence in Stroke. 2021, 1-19. DOI: 10.1007/978-3-030-58080-3_197-1.
- Misra S, Kasner S, Dawson J, Tanaka T, Zhao Y, Zaveri H, Eldem E, Vazquez J, Silva L, Mohidat S, Hickman L, Khan E, Funaro M, Nicolo J, Mazumder R, Yasuda C, Sunnerhagen K, Ihara M, Ross J, Liebeskind D, Kwan P, Quinn T, Engel J, Mishra N. Outcomes in Patients With Poststroke Seizures. JAMA Neurology 2023, 80: 1155-1165. PMID: 37721736, PMCID: PMC10507596, DOI: 10.1001/jamaneurol.2023.3240.
- Mishra N, Kwan P, Tanaka T, Sunnerhagen K, Dawson J, Zhao Y, Misra S, Wang S, Sharma V, Mazumder R, Funaro M, Ihara M, Nicolo J, Liebeskind D, Yasuda C, Cendes F, Quinn T, Ge Z, Scalzo F, Zelano J, Kasner S, Consortium I, Mishra N, Kwan P, Friedman A, Engel J. Clinical characteristics and outcomes of patients with post-stroke epilepsy: protocol for an individual patient data meta-analysis from the International Post-stroke Epilepsy Research Repository (IPSERR). BMJ Open 2023, 13: e078684. PMID: 37968000, PMCID: PMC10660442, DOI: 10.1136/bmjopen-2023-078684.
- Misra S, Khan E, Lam T, Mazumder R, Eldem E, Gururangan K, Hickman L, Goswami V, Funaro M, Montaner J, Quinn T, Liebeskind D, Mishra N. Biomarkers as prognostic determinants of epilepsy after post-acute central nervous system insults: a systematic review and meta-analysis (P3-5.017). Neurology 2023, 100 DOI: 10.1212/wnl.0000000000203165.
- Misra S, Vazquez J, Eldem E, Silva L, Mohidat S, Hickman L, Khan E, Funaro M, Yasuda C, Liebeskind D, Kasner S, Mishra N. Mortality and functional outcomes in patients with post-stroke epileptic seizures: a systematic review and meta-analysis (S45.006). Neurology 2023, 100 DOI: 10.1212/wnl.0000000000203419.
- Eldem E, Misra S, Quinn T, Driskell L, Perez A, Carrion C, Constable T, Schindler J, Zhao Y, Sico J, Hinman J, Allore H, Kiran S, Abutalebi J, Annoni J, Mishra N. Impact of Bilingualism on the Cognitive Outcomes in Stroke Survivors: A Systematic Review (P4-12.005). Neurology 2023, 100 DOI: 10.1212/wnl.0000000000203584.
- Fakhra S, Sattar Y, Patel N, Aziz S, Titus A, Almas T, Aamir M, Sulaiman S, Mishra N, Elgendy I, Raina S, Jagadeesan V, Daggubati R, Alraies M. Comparison of Sex-Based In-Hospital Procedural Outcomes and Hospital Readmission Frequency After Patent Foramen Ovale Occluder Device Placement: A Propensity Matched National Cohort. Current Problems In Cardiology 2023, 48: 101662. PMID: 36868331, DOI: 10.1016/j.cpcardiol.2023.101662.
- Misra S, Quinn T, Falcone G, Sharma V, De Havenon A, Zhao Y, Eldem E, Yasuda C, Dawson J, Liebeskind D, Kwan P, Mishra N. Abstract TP229: Impact Of Genetic Polymorphisms On The Risk Of Epilepsy Amongst Patients With Acute Brain Injury: A Systematic Review. Stroke 2023, 54: atp229-atp229. DOI: 10.1161/str.54.suppl_1.tp229.
- Tanaka T, Ihara M, Fukuma K, Mishra N, Koepp M, Guekht A, Ikeda A. Pathophysiology, Diagnosis, Prognosis, and Prevention of Poststroke Epilepsy. Neurology 2024, 102: e209450. PMID: 38759128, PMCID: PMC11175639, DOI: 10.1212/wnl.0000000000209450.
- Mishra N. Implications for driving based on the risk of seizures after ischaemic stroke. Journal Of Neurology Neurosurgery & Psychiatry 2024, 95: 794-794. PMID: 38749673, DOI: 10.1136/jnnp-2024-333772.
- Schneider D, Honda T, Feldmann E, de Havenon A, Romano J, Nogueira R, Prabhakaran S, Mishra N, Beaman C, Hinman J, Commichau C, Callas P, Kaneko N, Morales J, Patel S, Sharma L, Kim S, Taatjes‐Sommer H, Liebeskind D. Platelet FcγRIIa Expression in Ischemic Stroke: A Marker of Increased Platelet Reactivity. Stroke Vascular And Interventional Neurology 2022, 2 DOI: 10.1161/svin.121.000201.
- Mishra N, Liebeskind D. Artificial Intelligence in Stroke. 2022, 1733-1751. DOI: 10.1007/978-3-030-64573-1_197.
- Platelet FcγRIIa Expression in Ischemic Stroke: A Marker of Increased Platelet ReactivityPlatelet FcγRIIa Expression in Ischemic Stroke: A Marker of Increased Platelet Reactivity. J Schneider, Tristan Honda, Edward Feldmann, Adam de Havenon, Jose G Romano, Raul G Nogueira, Shyam Prabhakaran, Nishant K Mishra, Charles B Beaman, Jason Hinman, Christopher S Commichau, Peter Callas, Naoki Kaneko, Jose M Morales, Smit D Patel, Latisha K Sharma, Song Julia Kim, Heidi S Taatjes‐Sommer, David S Liebeskind (2022) Stroke: Vascular and Interventional Neurology. 2022; https://doi.org/10.1161/SVIN.121.000201
- Mishra NK, Leigh R, Campbell BCV. Editorial: Intracranial Bleeding After Reperfusion Therapy in Acute Ischemic Stroke. Frontiers In Neurology 2021, 12: 745993. PMID: 34531820, PMCID: PMC8438163, DOI: 10.3389/fneur.2021.745993.
- Mishra, N. K., Leigh, R., Campbell, B., eds. (2021). Intracranial Bleeding After Reperfusion Therapy in Acute Ischemic Stroke. Lausanne: Frontiers Media SA. doi: 10.3389/978-2-88971-508-4
- Mishra NK, Leigh R and Campbell BCV (2021) Editorial: Intracranial Bleeding After Reperfusion Therapy in Acute Ischemic Stroke. Front. Neurol. 12:745993. doi: 10.3389/fneur.2021.745993
- Mishra N.K., Liebeskind D.S. (2020) Artificial Intelligence in Stroke. In: Lidströmer N., Ashrafian H. (eds) Artificial Intelligence in Medicine. Springer, Cham. https://doi.org/10.1007/978-3-030-58080-3_197-1
- Reperfusion therapy for acute ischaemic stroke. Frontiers in Neurology. 2020 Edited by Nishant K. Mishra, MD; Bruce Campbell, MD.
- Mishra NK, Campbell BCV. Editorial: Reperfusion Therapy for Acute Ischemic Stroke. Frontiers In Neurology 2019, 10: 1139. PMID: 31736855, PMCID: PMC6828965, DOI: 10.3389/fneur.2019.01139.
- Zusterzeel R, Mishra NK, Beydoun H, Laschinger J, Wu C, Dong LM, Lin JA, Marinac-Dabic D, Strauss DG, Caños DA. Sex-Specific Outcomes After Transcatheter Aortic Valve Replacement: FDA Patient-Level Meta-Analysis of Premarket Clinical Trials. Journal Of Women's Health 2018, 27: 808-814. PMID: 29741978, DOI: 10.1089/jwh.2017.6760.
- Tsai JP, Mlynash M, Christensen S, Kemp S, Kim S, Mishra NK, Federau C, Nogueira RG, Jovin TG, Devlin TG, Akhtar N, Yavagal DR, Bammer R, Straka M, Zaharchuk G, Marks MP, Albers GW, Lansberg MG. Time From Imaging to Endovascular Reperfusion Predicts Outcome in Acute Stroke. Stroke 2018, 49: 952-957. PMID: 29581341, PMCID: PMC5875452, DOI: 10.1161/strokeaha.117.018858.
- Tsai J, Mlynash M, Christensen S, Kemp S, Kim S, Mishra N, Federau C, Nogueira R, Jovin T, Devlin T, Akhtar N, Yavagal D, Bammer R, Straka M, Zaharchuk G, Marks M, Lansberg M, Albers G. Abstract 81: Time From Imaging to Endovascular Reperfusion Predicts Outcome in Acute Stroke. Stroke 2018, 49 DOI: 10.1161/str.49.suppl_1.81.
- Lansberg MG, Christensen S, Kemp S, Mlynash M, Mishra N, Federau C, Tsai JP, Kim S, Nogueria RG, Jovin T, Devlin TG, Akhtar N, Yavagal DR, Haussen D, Dehkharghani S, Bammer R, Straka M, Zaharchuk G, Marks MP, Albers GW, Investigators F. Computed tomographic perfusion to Predict Response to Recanalization in ischemic stroke. Annals Of Neurology 2017, 81: 849-856. PMID: 28486789, PMCID: PMC5521988, DOI: 10.1002/ana.24953.
- Beydoun HA, Beydoun MA, Mishra NK, Rostant OS, Zonderman AB, Eid SM. Comorbid Parkinson's disease, falls and fractures in the 2010 National Emergency Department Sample. Parkinsonism & Related Disorders 2016, 35: 30-35. PMID: 27887896, PMCID: PMC5663222, DOI: 10.1016/j.parkreldis.2016.11.005.
- Kasasbeh AS, Christensen S, Straka M, Mishra N, Mlynash M, Bammer R, Albers GW, Lansberg MG. Optimal Computed Tomographic Perfusion Scan Duration for Assessment of Acute Stroke Lesion Volumes. Stroke 2016, 47: 2966-2971. PMID: 27895299, PMCID: PMC5134896, DOI: 10.1161/strokeaha.116.014177.
- Federau C, Christensen S, Mlynash M, Tsai J, Kim S, Zaharchuk G, Inoue M, Straka M, Mishra NK, Kemp S, Lansberg MG, Albers GW. Comparison of stroke volume evolution on diffusion-weighted imaging and fluid-attenuated inversion recovery following endovascular thrombectomy. International Journal Of Stroke 2016, 12: 510-518. PMID: 27811306, DOI: 10.1177/1747493016677985.
- Cereda CW, Christensen S, Campbell B, Mishra NK, Mlynash M, Levi C, Straka M, Wintermark M, Bammer R, Albers GW, Parsons MW, Lansberg MG. A benchmarking tool to evaluate computer tomography perfusion infarct core predictions against a DWI standard. Cerebrovascular And Brain Metabolism Reviews 2016, 36: 1780-1789. PMID: 26661203, PMCID: PMC5076783, DOI: 10.1177/0271678x15610586.
- Marks M, Christensen S, Tsai J, Mlynash M, Kemp S, Mishra N, Federau C, Kim S, Haussen D, Dehkharghani S, Devlin T, Yavagal D, Akhtar N, Jovin T, Nogueira R, Bammer R, Straka M, Zaharchuk G, Albers G, Lansberg M. Abstract WP34: Associations Between CTP Ischemic Core Volume, ASPECTS Scores and Clinical Outcomes After Endovascular Reperfusion. Stroke 2016, 47 DOI: 10.1161/str.47.suppl_1.wp34.
- Christensen S, Tsai J, Kemp S, Mishra N, Kim S, Mlynash M, Federau C, Bammer R, Frankel M, Dehkharghani S, Devlin T, Yavagal D, Straka M, Zaharchuk G, Akhtar N, Haussen D, Marks M, Jovin T, Nogueira R, Albers G, Lansberg M. Abstract WMP17: Severe CT Perfusion Bolus Delays Predict Infarct Growth Despite Reperfusion. Stroke 2016, 47 DOI: 10.1161/str.47.suppl_1.wmp17.
- Kim S, Christensen S, Mlynash M, Tsai J, Federau C, Kemp S, Mishra N, Frankel M, Dehkharghani S, Devlin T, Yavagal D, Akhtar N, Tudor J, Nogueira R, Bammer R, Straka M, Zaharchuk G, Albers G, Marks M, Lansberg M. Abstract WMP11: Arterial Occlusive Lesion Location Does Not Impact Functional Outcome in Patients with Endovascular Reperfusion. Stroke 2016, 47 DOI: 10.1161/str.47.suppl_1.wmp11.
- Tsai J, Mlynash M, Christensen S, Kemp S, Mishra N, Federau C, Kim S, Frankel M, Dehkharghani S, Devlin T, Yavagal D, Akhtar N, Jovin T, Nogueira R, Bammer R, Straka M, Zaharchuk G, Albers G, Marks M, Lansberg M. Abstract 6: Patient Selection is a Better Predictor of Good Outcome Than Time to Reperfusion in Acute Ischemic Stroke. Stroke 2016, 47 DOI: 10.1161/str.47.suppl_1.6.
- Mlynash M, Christensen S, Kemp S, Mishra N, Federau C, Tsai J, Kim S, Frankel M, Dehkharghani S, Devlin T, Yavagal D, Akhtar N, Jovin T, Nogueira R, Bammer R, Straka M, Zaharchuk G, Albers G, Marks M, Lansberg M. Abstract 158: The Malignant CTP Imaging Profile Predicts Worse Functional Outcomes. Stroke 2016, 47 DOI: 10.1161/str.47.suppl_1.158.
- Kasasbeh A, Christensen S, Straka M, Mishra N, Bammer R, Albers G, Lansberg M. Abstract TP38: Impact of CT Perfusion Scan Duration on Lesion Volume. Stroke 2016, 47 DOI: 10.1161/str.47.suppl_1.tp38.
- Lansberg M, Christensen S, Kemp S, Mlynash M, Mishra N, Federau C, Tsai J, Kim S, Haussen D, Dehkharghani S, Devlin T, Yavagal D, Akhtar N, Jovin T, Nogueira R, Bammer R, Straka M, Zaharchuk G, Marks M, Albers G. Abstract 57: Main Results of the CTP to Predict Response to Recanalization in Ischemic Stroke Project (CRISP). Stroke 2016, 47 DOI: 10.1161/str.47.suppl_1.57.
- Jusufovic M, Mishra NK, Lansberg MG, Bath PM, Berge E, Sandset EC. Blood Pressure Management in Acute Stroke. Current Hypertension Reviews 2016, 12: 121-6. PMID: 26931471, DOI: 10.2174/1573402112666160302102711.
- McGovern A, Pendlebury ST, Mishra NK, Fan Y, Quinn TJ. Test Accuracy of Informant-Based Cognitive Screening Tests for Diagnosis of Dementia and Multidomain Cognitive Impairment in Stroke. Stroke 2015, 47: 329-335. PMID: 26683423, DOI: 10.1161/strokeaha.115.011218.
- Lansberg MG, Cereda CW, Mlynash M, Mishra NK, Inoue M, Kemp S, Christensen S, Straka M, Zaharchuk G, Marks MP, Bammer R, Albers GW, Saver J, Fayad P, Howard G, Tomsick. T, Jovin T, Wechsler L, DeCesare S, Thai D, Sherr A, Wilder M, Tricot A, Lutsep H, McDaneld L, Larsen D, Czartoski T, Keogh B, Malik A, Brown A, Bernstein R, Muskovich K, Chang C, Stern T, Warach S, Davis L, Fazekas F, Seifert-Held T. Response to endovascular reperfusion is not time-dependent in patients with salvageable tissue. Neurology 2015, 85: 708-714. PMID: 26224727, PMCID: PMC4553034, DOI: 10.1212/wnl.0000000000001853.
- Mishra NK, Christensen S, Wouters A, Campbell BC, Straka M, Mlynash M, Kemp S, Cereda CW, Bammer R, Marks MP, Albers GW, Lansberg MG. Reperfusion of Very Low Cerebral Blood Volume Lesion Predicts Parenchymal Hematoma After Endovascular Therapy. Stroke 2015, 46: 1245-1249. PMID: 25828235, PMCID: PMC4414872, DOI: 10.1161/strokeaha.114.008171.
- Cereda C, Christensen S, Campbell B, Mishra N, Levi C, Mlynash M, Straka M, Bammer R, Albers G, Parson M, Lansberg M. Abstract W P49: Optimizing Ct Perfusion for Prediction of Ischemic Core in Acute Stroke With an Open-source Benchmarking Tool to Standardize Stroke Imaging Research. Stroke 2015, 46 DOI: 10.1161/str.46.suppl_1.wp49.
- Inoue M, Mlynash M, Cerada C, Mishra N, Christensen S, Straka M, Kemp S, Ichikawa H, Bammer R, Lansberg M, Albers G. Abstract W P48: Flair Vessel Hyper-intensities Could Predict Target Mismatch Signs in Acute Stroke Patients. Stroke 2015, 46 DOI: 10.1161/str.46.suppl_1.wp48.
- Lansberg MG, Mishra NK, Christensen S, Campbell B. Chapter: Perfusion profiles for favorable and unfavorable outcome. Book: MR & CT Perfusion Imaging: Clinical Applications and Theoretical Principles. Editor: Roland Bammer Publisher: Wolters Kluwer (2015)
- Mishra NK, Albers GW, Christensen S, Marks M, Hamilton S, Straka M, Liggins JT, Kemp S, Mlynash M, Bammer R, Lansberg MG. Comparison of Magnetic Resonance Imaging Mismatch Criteria to Select Patients for Endovascular Stroke Therapy. Stroke 2014, 45: 1369-1374. PMID: 24699054, PMCID: PMC4007191, DOI: 10.1161/strokeaha.114.004772.
- Mishra N, Christensen S, Straka M, Mlynash M, Kemp S, Bammer R, Marks M, Albers G, Lansberg M. Abstract T P46: Absence of a Very Low Cerebral Blood Volume (VLCBV) Lesion Identifies Patients Who Are Unlikely to Have Hemorrhagic Transformation After Delayed Endovascular Reperfusion. Stroke 2014, 45 DOI: 10.1161/str.45.suppl_1.tp46.
- Christensen S, Mishra N, Straka M, Fleischmann D, Bammer R, Zaharchuck G, Parsons M, Levi C, Albers G, Landsberg M. Abstract W P28: Precision of Tmax and CBF Lesion Volume Estimates in CT Perfusion Imaging. Stroke 2014, 45 DOI: 10.1161/str.45.suppl_1.wp28.
- Lansberg M, Lemmens R, Christensen S, Mishra N, Albers G. Abstract W P20: A Model to Calculate the Expected Treatment Effect in Acute Endovascular Stroke Trials. Stroke 2014, 45 DOI: 10.1161/str.45.suppl_1.wp20.
- Liggins JT, Yoo AJ, Mishra NK, Wheeler HM, Straka M, Leslie‐Mazwi T, Chaudhry ZA, Kemp S, Mlynash M, Bammer R, Albers GW, Lansberg MG, Investigators D. J. T. P. Liggins et al. International Journal Of Stroke 2013, 10: 705-709. PMID: 24207136, PMCID: PMC4048330, DOI: 10.1111/ijs.12207.
- Mishra NK, Mandava P, Chen C, Grotta J, Lees KR, Kent TA, collaboration V. Influence of racial differences on outcomes after thrombolytic therapy in acute ischemic stroke. International Journal Of Stroke 2013, 9: 613-617. PMID: 24148895, DOI: 10.1111/ijs.12162.
- Mishra NK, Chan BP, Teoh H, Meng C, Lees KR, Chen C, Sharma VK, collaboration F. Postthrombolysis outcomes in acute ischemic stroke patients of Asian race‐ethnicity. International Journal Of Stroke 2013, 8: 95-99. PMID: 23490069, DOI: 10.1111/ijs.12012.
- Frank B, Grotta JC, Alexandrov AV, Bluhmki E, Lyden P, Meretoja A, Mishra NK, Shuaib A, Wahlgren NG, Weimar C, Lees KR. Thrombolysis in Stroke Despite Contraindications or Warnings? Stroke 2013, 44: 727-733. PMID: 23391774, DOI: 10.1161/strokeaha.112.674622.
- Frank B, Grotta J, Alexandrov A, Bluhmki E, Lyden P, Meretoja A, Mishra N, Shuaib A, Wahlgren N, Weimar C, Lees K. Abstract WP70: Do Stroke Patients benefit from Thrombolysis despite Contraindications or Warnings? Stroke 2013, 44 DOI: 10.1161/str.44.suppl_1.awp70.
- Mishra N, Albers G, Lees K. Abstract WP390: Stroke Severity Threshold For Acute Stroke Trials. Stroke 2013, 44 DOI: 10.1161/str.44.suppl_1.awp390.
- Liggins J, Mishra N, Wheeler H, Inoue M, Straka M, Kemp S, Mlynash M, Bammer R, Albers G. Abstract WMP11: The Association between Endovascular Reperfusion and Favorable Clinical Response Is Similar in Older and Younger Stroke Patients. Stroke 2013, 44 DOI: 10.1161/str.44.suppl_1.awmp11.
- Liggins J, Mishra N, Wheeler H, Straka M, Kemp S, Mlynash M, Bammer R, Albers G, Lansberg M. Abstract WP22: A Scoring System Based on Age and DWI Volume Predicts Poor Functional Outcome Following Endovascular Treatment for Acute Ischemic Stroke. Stroke 2013, 44 DOI: 10.1161/str.44.suppl_1.awp22.
- Wheeler H, Mlynash M, Inoue M, Tipirneni A, Liggins J, Mishra N, Zaharchuk G, Straka M, Kemp S, Bammer R, Lansberg M, Albers G. Abstract 180: The Growth Rate of Early DWI Lesions is Highly Variable and Associated with Penumbral Salvage and Clinical Outcomes Following Endovascular Reperfusion. Stroke 2013, 44 DOI: 10.1161/str.44.suppl_1.a180.
- Mishra N, Albers G, Marks M, Liggins J, Hamilton S, Straka M, Kemp S, Mlynash M, Bammer R, Lansberg M. Abstract 179: Patient Selection for Endovascular Stroke Therapy: Can MRA substitute for PWI? Stroke 2013, 44 DOI: 10.1161/str.44.suppl_1.a179.
- Morgan TC, Dawson J, Spengler D, Lees KR, Aldrich C, Mishra NK, Lane K, Quinn TJ, Diener-West M, Weir CJ, Higgins P, Rafferty M, Kinsley K, Ziai W, Awad I, Walters MR, Hanley D. The Modified Graeb Score. Stroke 2013, 44: 635-641. PMID: 23370203, PMCID: PMC6800016, DOI: 10.1161/strokeaha.112.670653.
- Nishant K. Mishra. Use of thrombolytic therapy beyond current recommendations for acute ischaemic stroke; PhD Thesis; University of Glasgow, Scotland, UK
- Mishra NK, Ahmed N, Davalos A, Iversen HK, Melo T, Soinne L, Wahlgren N, Lees KR. Thrombolysis outcomes in acute ischemic stroke patients with prior stroke and diabetes mellitus. Neurology 2011, 77: 1866-1872. PMID: 22094479, DOI: 10.1212/wnl.0b013e318238ee42.
- Mishra NK, Russmann H, Granziera C, Maeder P, Annoni JM. Mutism and Amnesia following High-Voltage Electrical Injury: Psychogenic Symptomatology Triggered by Organic Dysfunction? European Neurology 2011, 66: 229-234. PMID: 21952143, DOI: 10.1159/000330953.
- Lees JS, Mishra NK, Saini M, Lyden PD, Shuaib A. Low Body Temperature Does Not Compromise the Treatment Effect of Alteplase. Stroke 2011, 42: 2618-2621. PMID: 21757664, DOI: 10.1161/strokeaha.110.611210.
- Mishra NK, Shuaib A, Lyden P, Diener HC, Grotta J, Davis S, Davalos A, Ashwood T, Wasiewski W, Lees KR. Home Time Is Extended in Patients With Ischemic Stroke Who Receive Thrombolytic Therapy. Stroke 2011, 42: 1046-1050. PMID: 21350199, DOI: 10.1161/strokeaha.110.601302.
- Lees K, Mishra N. Authors’ reply. The BMJ 2011, 342: d312. DOI: 10.1136/bmj.d312.
- Mishra NK, Ahmed N, Andersen G, Egido JA, Lindsberg PJ, Ringleb PA, Wahlgren NG, Lees KR. Thrombolysis in very elderly people: controlled comparison of SITS International Stroke Thrombolysis Registry and Virtual International Stroke Trials Archive. The BMJ 2010, 341: c6046. PMID: 21098614, PMCID: PMC2990864, DOI: 10.1136/bmj.c6046.
- Mishra NK, Diener HC, Lyden PD, Bluhmki E, Lees KR. Influence of Age on Outcome From Thrombolysis in Acute Stroke. Stroke 2010, 41: 2840-2848. PMID: 21030710, DOI: 10.1161/strokeaha.110.586206.
- Mishra NK, Lyden P, Grotta JC, Lees KR. Thrombolysis Is Associated With Consistent Functional Improvement Across Baseline Stroke Severity. Stroke 2010, 41: 2612-2617. PMID: 20947852, DOI: 10.1161/strokeaha.110.589317.
- Mishra NK, Davis SM, Kaste M, Lees KR, . Comparison of Outcomes Following Thrombolytic Therapy Among Patients With Prior Stroke and Diabetes in the Virtual International Stroke Trials Archive (VISTA). Diabetes Care 2010, 33: 2531-2537. PMID: 20843977, PMCID: PMC2992183, DOI: 10.2337/dc10-1125.
- Mishra NK, Khadilkar SV. Stroke program for India. Annals Of Indian Academy Of Neurology 2010, 13: 28-32. PMID: 20436743, PMCID: PMC2859584, DOI: 10.4103/0972-2327.61273.
- Mishra NK, Albers GW, Davis SM, Donnan GA, Furlan AJ, Hacke W, Lees KR. Mismatch-Based Delayed Thrombolysis. Stroke 2009, 41: e25-e33. PMID: 19926836, DOI: 10.1161/strokeaha.109.566869.
- Mishra NK, Rossetti AO, Ménétrey A, Carota A. Recurrent Wernicke's Aphasia: Migraine and Not Stroke! Headache The Journal Of Head And Face Pain 2008, 49: 765-768. PMID: 19456883, DOI: 10.1111/j.1526-4610.2008.01255.x.
- Mishra NK, Hastak S. Poststroke Hallucination Delusion Syndrome. Journal Of Neuropsychiatry 2008, 20: 116-116. PMID: 18305304, DOI: 10.1176/jnp.2008.20.1.116.
- Carota A, Mishra N, Allaoua M, Ghika J. A Squint of Brain: A Capgras Syndrome Variant. Journal Of Neuropsychiatry 2008, 20: 109-110. PMID: 18305297, DOI: 10.1176/jnp.2008.20.1.109.
- Mishra NK, Cereda C, Carota A. Lifetime Basilar Migraine: A Pontine Syndrome? Headache The Journal Of Head And Face Pain 2007, 48: 476-478. PMID: 18081824, DOI: 10.1111/j.1526-4610.2007.01001.x.
- Dalal PM, Mishra NK, Bhattacharjee M, Bhat P. Antithrombotic agents in cerebral ischaemia. The Journal Of The Association Of Physicians Of India 2006, 54: 555-61. PMID: 17089906.
- Mishra NK, Patel H, Hastak SM. Comprehensive stroke care: an overview. Journal Of Association Of Physicians Of India 2006, 54: 36-41. PMID: 16649738.
- Hastak SM, Gorawara PS, Mishra NK. Abulia: no will, no way. Journal Of Association Of Physicians Of India 2005, 53: 814-8. PMID: 16334629.
Biography
Nishant Kumar Mishra, MBBS, PhD, MD, is a neurologist who specializes in vascular neurology and stroke. “My goal is to make a positive impact in the lives of stroke patients, not only by offering the best care, but also by advancing the field through clinical research and novel discoveries,” he says.
Dr. Mishra says he became a doctor because he wanted to be of service to people. “We deal with stroke on a daily basis, but our patients are dealing with it for the first time,” he says. Often stroke patients are figuring out how to manage cognitive issues, changes in mood, or questions about why this happened to them. “So, I try to offer them a good deal of time to get a sense of exactly what is going on with them, and then put myself in their shoes,” Dr. Mishra says. “If I wasn’t the doctor, how would I expect to be treated?”
Before he came to Yale in 2021, Dr. Mishra worked at several major stroke centers and neurology institutes around the world, and was a clinical scientist at the Food and Drug Administration. He made significant contributions to the field through his doctoral work, informing whether the exclusion criteria proposed by drug authorities for the treatment of ischemic stroke patients were meaningful and should be followed.
He also pursues clinical research that spans the breadth of stroke care, including acute intervention, prevention, and post-stroke recovery. “I’ve spent a large part of my life not only improving the outcomes of patients by optimizing their medical care, but also though research in collaborative efforts with my colleagues, and that has contributed to significant changes to the way we treat patients, which has really encouraged me to keep going,” he says.
Titles
- Assistant Professor of Neurology
- Affiliated Faculty, Yale Institute of Global Health
- Stroke Director, U.S. Department of Veterans Affairs, West Haven VA Medical Center
Education & Training
- Vascular Neurology ACGME FellowUCLA (2021)
- NIH StrokeNet FellowUCLA (Mentors: J. Saver, MD; D.S. Liebeskind, MD) (2021)
- MDThe University of The State of New York, By Conferral (2020)
- Neurology ResidentMt. Sinai Hospital, Icahn School of Medicine at Mt. Sinai (2020)
- Neurology ResidentTulane University (2018)
- InternshipTulane University (2017)
- ORISE Medical ScientistUS Food and Drug Administration (2016)
- Postdoctoral Fellow in Vascular NeurologyStanford University (Mentors: G. Albers, MD; M. Lansberg, MD) (2014)
- PhDUniversity of Glasgow, Medicine and Therapeutics (Mentor: K.R. Lees, MD, FRCP) (2012)
- Visiting ResearcherUT Houston (Mentors: J. Grotta, MD; Collaborator: TA Kent, MD; P Mandava, MD) (2011)
- Visiting ESO researcherKarolinska University (Collaborator: N. Wahlgren, MD) (2009)
- ESKAS Clinical FellowUniversity of Lausanne, CHUV (Mentors: A. Carota, MD; J.M. Annoni, MD) (2008)
- MBBSMaharashtra University of Health Sciences, Nashik, India (2005)
Languages Spoken
- English
- हिन्दी (Hindi)
Additional Information
- Fellow of Royal College of Physician: Royal College of Physician, Glasgow (2023)
- StrokeNet Fellow, 2020-2021: NIH/ UCLA (2020)
- R25 NIH award: National Institutes of Health (2020)
- Leon Levy Foundation award: Leon Levy Foundation (2020)
- Exceptional Reviewer: Annals of Internal Medicine (2019)
- Exceptional Reviewer: Annals of Internal Medicine (2017)
- ORISE award: OWH/ US FDA/ Oak Ridge Institute for Science and Education (2015)
- Jim Gatheral Scholarship, UT Houston (Mentor: Dr. J Grotta): University of Glasgow, Scotland (2011)
- Department to Department SITS-ISTR collaboration award, Karolinska University, Sweden: European Stroke Organisation (2010)
- Overseas Research Studentship Award (ORSAS), University of Glasgow, Scotland, UK: UK Secretary of State for Education and Science (ORSAS) (2009)
- United Kingdom Research and Innovation/ Medical Research Council (UKRI/MRC) (2023 - Present): Grant reviewer
- American Indian Neurologist Association (2023 - Present): Executive Committee Member; https://www.4aina.com/Board
- All India Institute of Medical Sciences, New Delhi, India (2022 - Present): External examiner of a Ph.D. in Neurology thesis; Ref: AIIMS/ExamSec/Ph.D/12-04/2022
- Association of Indian Neurologist Association (2022 - Present): Member
- American Heart Association (2022 - Present): FAHA
- Neurology (Green Journal) (2022 - Present): Editorial Board Member
- Clinical Neurology and Neurosurgery (2022 - Present): Reviewer
- Alzheimers Disease and Associated Disorders (2022 - Present): Reviewer
- BMJ Surgery, Interventions, and Health Technologies (2022 - Present): Reviewer
- International Post-Stroke Epilepsy Research Consortium (IPSERC) (2021 - Present): Convenor, IPSERC.
- Mishra NK, Engel J, Liebeskind DS, Sharma VK, Hirsch LJ, Kasner SE, French JA, Devinsky O, Friedman A, Dawson J, Quinn TJ, Selim M, de Havenon A, Yasuda CL, Cendes F, Benninger F, Zaveri HP, Burneo JG, Srivastava P, Singh M, Bhatia R, Vishnu VY, Bentes C, Ferro J, Weiss S, Sivaraju A, Kim JA, Galovic M, Gilmore EJ, Pitkänen A, Davis K, Sansing LH, Sheth KN, Paz JT, Singh A, Sheth S, Worrall BB, Grotta JC, Casillas-Espinos PM, Chen Z, Nicolo JP, Yan B, Kwan P, Consortium F. International Post Stroke Epilepsy Research Consortium (IPSERC): A consortium to accelerate discoveries in preventing epileptogenesis after stroke. Epilepsy & Behavior 2021, 127: 108502. PMID: 34968775, DOI: 10.1016/j.yebeh.2021.108502.
- Misra S, Quinn T, Falcone G, Sharma V, de Havenon A, Zhao Y, Eldem E, French J, Yasuda C, Dawson J, Liebeskind D, Kwan P, Mishra N. Impact of genetic polymorphisms on the risk of epilepsy amongst patients with acute brain injury: A systematic review. European Journal Of Neurology 2023, 30: 1791-1800. PMID: 36912749, DOI: 10.1111/ene.15777.
- Misra S, Khan E, Lam T, Mazumder R, Gururangan K, Hickman L, Goswami V, Funaro M, Eldem E, Sansing L, Sico J, Quinn T, Liebeskind D, Montaner J, Kwan P, Mishra N. Common Pathways of Epileptogenesis in Patients With Epilepsy Post–Brain Injury. Neurology 2023, 101: e2243-e2256. PMID: 37550071, PMCID: PMC10727219, DOI: 10.1212/wnl.0000000000207749.
- Mishra N, Liebeskind D. Artificial Intelligence in Stroke. 2021, 1-19. DOI: 10.1007/978-3-030-58080-3_197-1.
- Misra S, Kasner S, Dawson J, Tanaka T, Zhao Y, Zaveri H, Eldem E, Vazquez J, Silva L, Mohidat S, Hickman L, Khan E, Funaro M, Nicolo J, Mazumder R, Yasuda C, Sunnerhagen K, Ihara M, Ross J, Liebeskind D, Kwan P, Quinn T, Engel J, Mishra N. Outcomes in Patients With Poststroke Seizures. JAMA Neurology 2023, 80: 1155-1165. PMID: 37721736, PMCID: PMC10507596, DOI: 10.1001/jamaneurol.2023.3240.
- Mishra N, Kwan P, Tanaka T, Sunnerhagen K, Dawson J, Zhao Y, Misra S, Wang S, Sharma V, Mazumder R, Funaro M, Ihara M, Nicolo J, Liebeskind D, Yasuda C, Cendes F, Quinn T, Ge Z, Scalzo F, Zelano J, Kasner S, Consortium I, Mishra N, Kwan P, Friedman A, Engel J. Clinical characteristics and outcomes of patients with post-stroke epilepsy: protocol for an individual patient data meta-analysis from the International Post-stroke Epilepsy Research Repository (IPSERR). BMJ Open 2023, 13: e078684. PMID: 37968000, PMCID: PMC10660442, DOI: 10.1136/bmjopen-2023-078684.
- Misra S, Khan E, Lam T, Mazumder R, Eldem E, Gururangan K, Hickman L, Goswami V, Funaro M, Montaner J, Quinn T, Liebeskind D, Mishra N. Biomarkers as prognostic determinants of epilepsy after post-acute central nervous system insults: a systematic review and meta-analysis (P3-5.017). Neurology 2023, 100 DOI: 10.1212/wnl.0000000000203165.
- Misra S, Vazquez J, Eldem E, Silva L, Mohidat S, Hickman L, Khan E, Funaro M, Yasuda C, Liebeskind D, Kasner S, Mishra N. Mortality and functional outcomes in patients with post-stroke epileptic seizures: a systematic review and meta-analysis (S45.006). Neurology 2023, 100 DOI: 10.1212/wnl.0000000000203419.
- Eldem E, Misra S, Quinn T, Driskell L, Perez A, Carrion C, Constable T, Schindler J, Zhao Y, Sico J, Hinman J, Allore H, Kiran S, Abutalebi J, Annoni J, Mishra N. Impact of Bilingualism on the Cognitive Outcomes in Stroke Survivors: A Systematic Review (P4-12.005). Neurology 2023, 100 DOI: 10.1212/wnl.0000000000203584.
- Fakhra S, Sattar Y, Patel N, Aziz S, Titus A, Almas T, Aamir M, Sulaiman S, Mishra N, Elgendy I, Raina S, Jagadeesan V, Daggubati R, Alraies M. Comparison of Sex-Based In-Hospital Procedural Outcomes and Hospital Readmission Frequency After Patent Foramen Ovale Occluder Device Placement: A Propensity Matched National Cohort. Current Problems In Cardiology 2023, 48: 101662. PMID: 36868331, DOI: 10.1016/j.cpcardiol.2023.101662.
- Misra S, Quinn T, Falcone G, Sharma V, De Havenon A, Zhao Y, Eldem E, Yasuda C, Dawson J, Liebeskind D, Kwan P, Mishra N. Abstract TP229: Impact Of Genetic Polymorphisms On The Risk Of Epilepsy Amongst Patients With Acute Brain Injury: A Systematic Review. Stroke 2023, 54: atp229-atp229. DOI: 10.1161/str.54.suppl_1.tp229.
- Tanaka T, Ihara M, Fukuma K, Mishra N, Koepp M, Guekht A, Ikeda A. Pathophysiology, Diagnosis, Prognosis, and Prevention of Poststroke Epilepsy. Neurology 2024, 102: e209450. PMID: 38759128, PMCID: PMC11175639, DOI: 10.1212/wnl.0000000000209450.
- Mishra N. Implications for driving based on the risk of seizures after ischaemic stroke. Journal Of Neurology Neurosurgery & Psychiatry 2024, 95: 794-794. PMID: 38749673, DOI: 10.1136/jnnp-2024-333772.
- Schneider D, Honda T, Feldmann E, de Havenon A, Romano J, Nogueira R, Prabhakaran S, Mishra N, Beaman C, Hinman J, Commichau C, Callas P, Kaneko N, Morales J, Patel S, Sharma L, Kim S, Taatjes‐Sommer H, Liebeskind D. Platelet FcγRIIa Expression in Ischemic Stroke: A Marker of Increased Platelet Reactivity. Stroke Vascular And Interventional Neurology 2022, 2 DOI: 10.1161/svin.121.000201.
- Mishra N, Liebeskind D. Artificial Intelligence in Stroke. 2022, 1733-1751. DOI: 10.1007/978-3-030-64573-1_197.
- Platelet FcγRIIa Expression in Ischemic Stroke: A Marker of Increased Platelet ReactivityPlatelet FcγRIIa Expression in Ischemic Stroke: A Marker of Increased Platelet Reactivity. J Schneider, Tristan Honda, Edward Feldmann, Adam de Havenon, Jose G Romano, Raul G Nogueira, Shyam Prabhakaran, Nishant K Mishra, Charles B Beaman, Jason Hinman, Christopher S Commichau, Peter Callas, Naoki Kaneko, Jose M Morales, Smit D Patel, Latisha K Sharma, Song Julia Kim, Heidi S Taatjes‐Sommer, David S Liebeskind (2022) Stroke: Vascular and Interventional Neurology. 2022; https://doi.org/10.1161/SVIN.121.000201
- Mishra NK, Leigh R, Campbell BCV. Editorial: Intracranial Bleeding After Reperfusion Therapy in Acute Ischemic Stroke. Frontiers In Neurology 2021, 12: 745993. PMID: 34531820, PMCID: PMC8438163, DOI: 10.3389/fneur.2021.745993.
- Mishra, N. K., Leigh, R., Campbell, B., eds. (2021). Intracranial Bleeding After Reperfusion Therapy in Acute Ischemic Stroke. Lausanne: Frontiers Media SA. doi: 10.3389/978-2-88971-508-4
- Mishra NK, Leigh R and Campbell BCV (2021) Editorial: Intracranial Bleeding After Reperfusion Therapy in Acute Ischemic Stroke. Front. Neurol. 12:745993. doi: 10.3389/fneur.2021.745993
- Mishra N.K., Liebeskind D.S. (2020) Artificial Intelligence in Stroke. In: Lidströmer N., Ashrafian H. (eds) Artificial Intelligence in Medicine. Springer, Cham. https://doi.org/10.1007/978-3-030-58080-3_197-1
- Reperfusion therapy for acute ischaemic stroke. Frontiers in Neurology. 2020 Edited by Nishant K. Mishra, MD; Bruce Campbell, MD.
- Mishra NK, Campbell BCV. Editorial: Reperfusion Therapy for Acute Ischemic Stroke. Frontiers In Neurology 2019, 10: 1139. PMID: 31736855, PMCID: PMC6828965, DOI: 10.3389/fneur.2019.01139.
- Zusterzeel R, Mishra NK, Beydoun H, Laschinger J, Wu C, Dong LM, Lin JA, Marinac-Dabic D, Strauss DG, Caños DA. Sex-Specific Outcomes After Transcatheter Aortic Valve Replacement: FDA Patient-Level Meta-Analysis of Premarket Clinical Trials. Journal Of Women's Health 2018, 27: 808-814. PMID: 29741978, DOI: 10.1089/jwh.2017.6760.
- Tsai JP, Mlynash M, Christensen S, Kemp S, Kim S, Mishra NK, Federau C, Nogueira RG, Jovin TG, Devlin TG, Akhtar N, Yavagal DR, Bammer R, Straka M, Zaharchuk G, Marks MP, Albers GW, Lansberg MG. Time From Imaging to Endovascular Reperfusion Predicts Outcome in Acute Stroke. Stroke 2018, 49: 952-957. PMID: 29581341, PMCID: PMC5875452, DOI: 10.1161/strokeaha.117.018858.
- Tsai J, Mlynash M, Christensen S, Kemp S, Kim S, Mishra N, Federau C, Nogueira R, Jovin T, Devlin T, Akhtar N, Yavagal D, Bammer R, Straka M, Zaharchuk G, Marks M, Lansberg M, Albers G. Abstract 81: Time From Imaging to Endovascular Reperfusion Predicts Outcome in Acute Stroke. Stroke 2018, 49 DOI: 10.1161/str.49.suppl_1.81.
- Lansberg MG, Christensen S, Kemp S, Mlynash M, Mishra N, Federau C, Tsai JP, Kim S, Nogueria RG, Jovin T, Devlin TG, Akhtar N, Yavagal DR, Haussen D, Dehkharghani S, Bammer R, Straka M, Zaharchuk G, Marks MP, Albers GW, Investigators F. Computed tomographic perfusion to Predict Response to Recanalization in ischemic stroke. Annals Of Neurology 2017, 81: 849-856. PMID: 28486789, PMCID: PMC5521988, DOI: 10.1002/ana.24953.
- Beydoun HA, Beydoun MA, Mishra NK, Rostant OS, Zonderman AB, Eid SM. Comorbid Parkinson's disease, falls and fractures in the 2010 National Emergency Department Sample. Parkinsonism & Related Disorders 2016, 35: 30-35. PMID: 27887896, PMCID: PMC5663222, DOI: 10.1016/j.parkreldis.2016.11.005.
- Kasasbeh AS, Christensen S, Straka M, Mishra N, Mlynash M, Bammer R, Albers GW, Lansberg MG. Optimal Computed Tomographic Perfusion Scan Duration for Assessment of Acute Stroke Lesion Volumes. Stroke 2016, 47: 2966-2971. PMID: 27895299, PMCID: PMC5134896, DOI: 10.1161/strokeaha.116.014177.
- Federau C, Christensen S, Mlynash M, Tsai J, Kim S, Zaharchuk G, Inoue M, Straka M, Mishra NK, Kemp S, Lansberg MG, Albers GW. Comparison of stroke volume evolution on diffusion-weighted imaging and fluid-attenuated inversion recovery following endovascular thrombectomy. International Journal Of Stroke 2016, 12: 510-518. PMID: 27811306, DOI: 10.1177/1747493016677985.
- Cereda CW, Christensen S, Campbell B, Mishra NK, Mlynash M, Levi C, Straka M, Wintermark M, Bammer R, Albers GW, Parsons MW, Lansberg MG. A benchmarking tool to evaluate computer tomography perfusion infarct core predictions against a DWI standard. Cerebrovascular And Brain Metabolism Reviews 2016, 36: 1780-1789. PMID: 26661203, PMCID: PMC5076783, DOI: 10.1177/0271678x15610586.
- Marks M, Christensen S, Tsai J, Mlynash M, Kemp S, Mishra N, Federau C, Kim S, Haussen D, Dehkharghani S, Devlin T, Yavagal D, Akhtar N, Jovin T, Nogueira R, Bammer R, Straka M, Zaharchuk G, Albers G, Lansberg M. Abstract WP34: Associations Between CTP Ischemic Core Volume, ASPECTS Scores and Clinical Outcomes After Endovascular Reperfusion. Stroke 2016, 47 DOI: 10.1161/str.47.suppl_1.wp34.
- Christensen S, Tsai J, Kemp S, Mishra N, Kim S, Mlynash M, Federau C, Bammer R, Frankel M, Dehkharghani S, Devlin T, Yavagal D, Straka M, Zaharchuk G, Akhtar N, Haussen D, Marks M, Jovin T, Nogueira R, Albers G, Lansberg M. Abstract WMP17: Severe CT Perfusion Bolus Delays Predict Infarct Growth Despite Reperfusion. Stroke 2016, 47 DOI: 10.1161/str.47.suppl_1.wmp17.
- Kim S, Christensen S, Mlynash M, Tsai J, Federau C, Kemp S, Mishra N, Frankel M, Dehkharghani S, Devlin T, Yavagal D, Akhtar N, Tudor J, Nogueira R, Bammer R, Straka M, Zaharchuk G, Albers G, Marks M, Lansberg M. Abstract WMP11: Arterial Occlusive Lesion Location Does Not Impact Functional Outcome in Patients with Endovascular Reperfusion. Stroke 2016, 47 DOI: 10.1161/str.47.suppl_1.wmp11.
- Tsai J, Mlynash M, Christensen S, Kemp S, Mishra N, Federau C, Kim S, Frankel M, Dehkharghani S, Devlin T, Yavagal D, Akhtar N, Jovin T, Nogueira R, Bammer R, Straka M, Zaharchuk G, Albers G, Marks M, Lansberg M. Abstract 6: Patient Selection is a Better Predictor of Good Outcome Than Time to Reperfusion in Acute Ischemic Stroke. Stroke 2016, 47 DOI: 10.1161/str.47.suppl_1.6.
- Mlynash M, Christensen S, Kemp S, Mishra N, Federau C, Tsai J, Kim S, Frankel M, Dehkharghani S, Devlin T, Yavagal D, Akhtar N, Jovin T, Nogueira R, Bammer R, Straka M, Zaharchuk G, Albers G, Marks M, Lansberg M. Abstract 158: The Malignant CTP Imaging Profile Predicts Worse Functional Outcomes. Stroke 2016, 47 DOI: 10.1161/str.47.suppl_1.158.
- Kasasbeh A, Christensen S, Straka M, Mishra N, Bammer R, Albers G, Lansberg M. Abstract TP38: Impact of CT Perfusion Scan Duration on Lesion Volume. Stroke 2016, 47 DOI: 10.1161/str.47.suppl_1.tp38.
- Lansberg M, Christensen S, Kemp S, Mlynash M, Mishra N, Federau C, Tsai J, Kim S, Haussen D, Dehkharghani S, Devlin T, Yavagal D, Akhtar N, Jovin T, Nogueira R, Bammer R, Straka M, Zaharchuk G, Marks M, Albers G. Abstract 57: Main Results of the CTP to Predict Response to Recanalization in Ischemic Stroke Project (CRISP). Stroke 2016, 47 DOI: 10.1161/str.47.suppl_1.57.
- Jusufovic M, Mishra NK, Lansberg MG, Bath PM, Berge E, Sandset EC. Blood Pressure Management in Acute Stroke. Current Hypertension Reviews 2016, 12: 121-6. PMID: 26931471, DOI: 10.2174/1573402112666160302102711.
- McGovern A, Pendlebury ST, Mishra NK, Fan Y, Quinn TJ. Test Accuracy of Informant-Based Cognitive Screening Tests for Diagnosis of Dementia and Multidomain Cognitive Impairment in Stroke. Stroke 2015, 47: 329-335. PMID: 26683423, DOI: 10.1161/strokeaha.115.011218.
- Lansberg MG, Cereda CW, Mlynash M, Mishra NK, Inoue M, Kemp S, Christensen S, Straka M, Zaharchuk G, Marks MP, Bammer R, Albers GW, Saver J, Fayad P, Howard G, Tomsick. T, Jovin T, Wechsler L, DeCesare S, Thai D, Sherr A, Wilder M, Tricot A, Lutsep H, McDaneld L, Larsen D, Czartoski T, Keogh B, Malik A, Brown A, Bernstein R, Muskovich K, Chang C, Stern T, Warach S, Davis L, Fazekas F, Seifert-Held T. Response to endovascular reperfusion is not time-dependent in patients with salvageable tissue. Neurology 2015, 85: 708-714. PMID: 26224727, PMCID: PMC4553034, DOI: 10.1212/wnl.0000000000001853.
- Mishra NK, Christensen S, Wouters A, Campbell BC, Straka M, Mlynash M, Kemp S, Cereda CW, Bammer R, Marks MP, Albers GW, Lansberg MG. Reperfusion of Very Low Cerebral Blood Volume Lesion Predicts Parenchymal Hematoma After Endovascular Therapy. Stroke 2015, 46: 1245-1249. PMID: 25828235, PMCID: PMC4414872, DOI: 10.1161/strokeaha.114.008171.
- Cereda C, Christensen S, Campbell B, Mishra N, Levi C, Mlynash M, Straka M, Bammer R, Albers G, Parson M, Lansberg M. Abstract W P49: Optimizing Ct Perfusion for Prediction of Ischemic Core in Acute Stroke With an Open-source Benchmarking Tool to Standardize Stroke Imaging Research. Stroke 2015, 46 DOI: 10.1161/str.46.suppl_1.wp49.
- Inoue M, Mlynash M, Cerada C, Mishra N, Christensen S, Straka M, Kemp S, Ichikawa H, Bammer R, Lansberg M, Albers G. Abstract W P48: Flair Vessel Hyper-intensities Could Predict Target Mismatch Signs in Acute Stroke Patients. Stroke 2015, 46 DOI: 10.1161/str.46.suppl_1.wp48.
- Lansberg MG, Mishra NK, Christensen S, Campbell B. Chapter: Perfusion profiles for favorable and unfavorable outcome. Book: MR & CT Perfusion Imaging: Clinical Applications and Theoretical Principles. Editor: Roland Bammer Publisher: Wolters Kluwer (2015)
- Mishra NK, Albers GW, Christensen S, Marks M, Hamilton S, Straka M, Liggins JT, Kemp S, Mlynash M, Bammer R, Lansberg MG. Comparison of Magnetic Resonance Imaging Mismatch Criteria to Select Patients for Endovascular Stroke Therapy. Stroke 2014, 45: 1369-1374. PMID: 24699054, PMCID: PMC4007191, DOI: 10.1161/strokeaha.114.004772.
- Mishra N, Christensen S, Straka M, Mlynash M, Kemp S, Bammer R, Marks M, Albers G, Lansberg M. Abstract T P46: Absence of a Very Low Cerebral Blood Volume (VLCBV) Lesion Identifies Patients Who Are Unlikely to Have Hemorrhagic Transformation After Delayed Endovascular Reperfusion. Stroke 2014, 45 DOI: 10.1161/str.45.suppl_1.tp46.
- Christensen S, Mishra N, Straka M, Fleischmann D, Bammer R, Zaharchuck G, Parsons M, Levi C, Albers G, Landsberg M. Abstract W P28: Precision of Tmax and CBF Lesion Volume Estimates in CT Perfusion Imaging. Stroke 2014, 45 DOI: 10.1161/str.45.suppl_1.wp28.
- Lansberg M, Lemmens R, Christensen S, Mishra N, Albers G. Abstract W P20: A Model to Calculate the Expected Treatment Effect in Acute Endovascular Stroke Trials. Stroke 2014, 45 DOI: 10.1161/str.45.suppl_1.wp20.
- Liggins JT, Yoo AJ, Mishra NK, Wheeler HM, Straka M, Leslie‐Mazwi T, Chaudhry ZA, Kemp S, Mlynash M, Bammer R, Albers GW, Lansberg MG, Investigators D. J. T. P. Liggins et al. International Journal Of Stroke 2013, 10: 705-709. PMID: 24207136, PMCID: PMC4048330, DOI: 10.1111/ijs.12207.
- Mishra NK, Mandava P, Chen C, Grotta J, Lees KR, Kent TA, collaboration V. Influence of racial differences on outcomes after thrombolytic therapy in acute ischemic stroke. International Journal Of Stroke 2013, 9: 613-617. PMID: 24148895, DOI: 10.1111/ijs.12162.
- Mishra NK, Chan BP, Teoh H, Meng C, Lees KR, Chen C, Sharma VK, collaboration F. Postthrombolysis outcomes in acute ischemic stroke patients of Asian race‐ethnicity. International Journal Of Stroke 2013, 8: 95-99. PMID: 23490069, DOI: 10.1111/ijs.12012.
- Frank B, Grotta JC, Alexandrov AV, Bluhmki E, Lyden P, Meretoja A, Mishra NK, Shuaib A, Wahlgren NG, Weimar C, Lees KR. Thrombolysis in Stroke Despite Contraindications or Warnings? Stroke 2013, 44: 727-733. PMID: 23391774, DOI: 10.1161/strokeaha.112.674622.
- Frank B, Grotta J, Alexandrov A, Bluhmki E, Lyden P, Meretoja A, Mishra N, Shuaib A, Wahlgren N, Weimar C, Lees K. Abstract WP70: Do Stroke Patients benefit from Thrombolysis despite Contraindications or Warnings? Stroke 2013, 44 DOI: 10.1161/str.44.suppl_1.awp70.
- Mishra N, Albers G, Lees K. Abstract WP390: Stroke Severity Threshold For Acute Stroke Trials. Stroke 2013, 44 DOI: 10.1161/str.44.suppl_1.awp390.
- Liggins J, Mishra N, Wheeler H, Inoue M, Straka M, Kemp S, Mlynash M, Bammer R, Albers G. Abstract WMP11: The Association between Endovascular Reperfusion and Favorable Clinical Response Is Similar in Older and Younger Stroke Patients. Stroke 2013, 44 DOI: 10.1161/str.44.suppl_1.awmp11.
- Liggins J, Mishra N, Wheeler H, Straka M, Kemp S, Mlynash M, Bammer R, Albers G, Lansberg M. Abstract WP22: A Scoring System Based on Age and DWI Volume Predicts Poor Functional Outcome Following Endovascular Treatment for Acute Ischemic Stroke. Stroke 2013, 44 DOI: 10.1161/str.44.suppl_1.awp22.
- Wheeler H, Mlynash M, Inoue M, Tipirneni A, Liggins J, Mishra N, Zaharchuk G, Straka M, Kemp S, Bammer R, Lansberg M, Albers G. Abstract 180: The Growth Rate of Early DWI Lesions is Highly Variable and Associated with Penumbral Salvage and Clinical Outcomes Following Endovascular Reperfusion. Stroke 2013, 44 DOI: 10.1161/str.44.suppl_1.a180.
- Mishra N, Albers G, Marks M, Liggins J, Hamilton S, Straka M, Kemp S, Mlynash M, Bammer R, Lansberg M. Abstract 179: Patient Selection for Endovascular Stroke Therapy: Can MRA substitute for PWI? Stroke 2013, 44 DOI: 10.1161/str.44.suppl_1.a179.
- Morgan TC, Dawson J, Spengler D, Lees KR, Aldrich C, Mishra NK, Lane K, Quinn TJ, Diener-West M, Weir CJ, Higgins P, Rafferty M, Kinsley K, Ziai W, Awad I, Walters MR, Hanley D. The Modified Graeb Score. Stroke 2013, 44: 635-641. PMID: 23370203, PMCID: PMC6800016, DOI: 10.1161/strokeaha.112.670653.
- Nishant K. Mishra. Use of thrombolytic therapy beyond current recommendations for acute ischaemic stroke; PhD Thesis; University of Glasgow, Scotland, UK
- Mishra NK, Ahmed N, Davalos A, Iversen HK, Melo T, Soinne L, Wahlgren N, Lees KR. Thrombolysis outcomes in acute ischemic stroke patients with prior stroke and diabetes mellitus. Neurology 2011, 77: 1866-1872. PMID: 22094479, DOI: 10.1212/wnl.0b013e318238ee42.
- Mishra NK, Russmann H, Granziera C, Maeder P, Annoni JM. Mutism and Amnesia following High-Voltage Electrical Injury: Psychogenic Symptomatology Triggered by Organic Dysfunction? European Neurology 2011, 66: 229-234. PMID: 21952143, DOI: 10.1159/000330953.
- Lees JS, Mishra NK, Saini M, Lyden PD, Shuaib A. Low Body Temperature Does Not Compromise the Treatment Effect of Alteplase. Stroke 2011, 42: 2618-2621. PMID: 21757664, DOI: 10.1161/strokeaha.110.611210.
- Mishra NK, Shuaib A, Lyden P, Diener HC, Grotta J, Davis S, Davalos A, Ashwood T, Wasiewski W, Lees KR. Home Time Is Extended in Patients With Ischemic Stroke Who Receive Thrombolytic Therapy. Stroke 2011, 42: 1046-1050. PMID: 21350199, DOI: 10.1161/strokeaha.110.601302.
- Lees K, Mishra N. Authors’ reply. The BMJ 2011, 342: d312. DOI: 10.1136/bmj.d312.
- Mishra NK, Ahmed N, Andersen G, Egido JA, Lindsberg PJ, Ringleb PA, Wahlgren NG, Lees KR. Thrombolysis in very elderly people: controlled comparison of SITS International Stroke Thrombolysis Registry and Virtual International Stroke Trials Archive. The BMJ 2010, 341: c6046. PMID: 21098614, PMCID: PMC2990864, DOI: 10.1136/bmj.c6046.
- Mishra NK, Diener HC, Lyden PD, Bluhmki E, Lees KR. Influence of Age on Outcome From Thrombolysis in Acute Stroke. Stroke 2010, 41: 2840-2848. PMID: 21030710, DOI: 10.1161/strokeaha.110.586206.
- Mishra NK, Lyden P, Grotta JC, Lees KR. Thrombolysis Is Associated With Consistent Functional Improvement Across Baseline Stroke Severity. Stroke 2010, 41: 2612-2617. PMID: 20947852, DOI: 10.1161/strokeaha.110.589317.
- Mishra NK, Davis SM, Kaste M, Lees KR, . Comparison of Outcomes Following Thrombolytic Therapy Among Patients With Prior Stroke and Diabetes in the Virtual International Stroke Trials Archive (VISTA). Diabetes Care 2010, 33: 2531-2537. PMID: 20843977, PMCID: PMC2992183, DOI: 10.2337/dc10-1125.
- Mishra NK, Khadilkar SV. Stroke program for India. Annals Of Indian Academy Of Neurology 2010, 13: 28-32. PMID: 20436743, PMCID: PMC2859584, DOI: 10.4103/0972-2327.61273.
- Mishra NK, Albers GW, Davis SM, Donnan GA, Furlan AJ, Hacke W, Lees KR. Mismatch-Based Delayed Thrombolysis. Stroke 2009, 41: e25-e33. PMID: 19926836, DOI: 10.1161/strokeaha.109.566869.
- Mishra NK, Rossetti AO, Ménétrey A, Carota A. Recurrent Wernicke's Aphasia: Migraine and Not Stroke! Headache The Journal Of Head And Face Pain 2008, 49: 765-768. PMID: 19456883, DOI: 10.1111/j.1526-4610.2008.01255.x.
- Mishra NK, Hastak S. Poststroke Hallucination Delusion Syndrome. Journal Of Neuropsychiatry 2008, 20: 116-116. PMID: 18305304, DOI: 10.1176/jnp.2008.20.1.116.
- Carota A, Mishra N, Allaoua M, Ghika J. A Squint of Brain: A Capgras Syndrome Variant. Journal Of Neuropsychiatry 2008, 20: 109-110. PMID: 18305297, DOI: 10.1176/jnp.2008.20.1.109.
- Mishra NK, Cereda C, Carota A. Lifetime Basilar Migraine: A Pontine Syndrome? Headache The Journal Of Head And Face Pain 2007, 48: 476-478. PMID: 18081824, DOI: 10.1111/j.1526-4610.2007.01001.x.
- Dalal PM, Mishra NK, Bhattacharjee M, Bhat P. Antithrombotic agents in cerebral ischaemia. The Journal Of The Association Of Physicians Of India 2006, 54: 555-61. PMID: 17089906.
- Mishra NK, Patel H, Hastak SM. Comprehensive stroke care: an overview. Journal Of Association Of Physicians Of India 2006, 54: 36-41. PMID: 16649738.
- Hastak SM, Gorawara PS, Mishra NK. Abulia: no will, no way. Journal Of Association Of Physicians Of India 2005, 53: 814-8. PMID: 16334629.