- Yale Center for Infectious Disease200 Orchard StreetNew Haven, CT 06511
- Yale Infectious DiseasesYale New Haven Hospital20 York StreetNew Haven, CT 06510
Merceditas Villanueva, MD
Biography
Merceditas S. Villanueva, MD, director of the Yale Medicine AIDS Care Program, is an infectious disease specialist with a clinical focus on HIV and AIDS. She cares for patients in the hospital who are sick with various infections, as well as those with complications of HIV. She also treats patients in the Nathan Smith Clinic, where she primarily treats HIV.
As a clinician, Dr. Villanueva believes in getting to know each patient as an individual. “I think that way you really make a difference in people's lives,” she says. “Sometimes we think it has to be this huge thing that you do for people. But it's the little things that you notice that will make a difference—the ability to hear them, the ability to link them to the right resources if they need it.” People living with HIV have different needs that require resources beyond strict medical care, she says. “A team approach including community-based partners is essential.”
Dr. Villanueva was drawn to the field of infectious diseases after traveling to different countries with her father, who worked for the United Nations. She saw many people who struggled with diseases that called for medical care within the context of global public health concerns. “I always felt that it would be great to make an impact in those communities,” Dr. Villanueva says. The field of HIV pulled all those interests together.
AIDS was a uniformly fatal disease when Dr. Villanueva was a medical student in the early 1980s. In the last two to three decades, increasingly better treatments have made HIV a chronic disease. “The message that we gave patients in the early days was, ‘Let's try to make your remaining days as comfortable as possible.’ But that message has totally changed. HIV is not curable, but as long as people take their medications, it’s controllable, so people living with HIV can lead, more or less, normal lives.” As such, doctors and researchers are turning their attention to people with HIV who are surviving into their 50s and 60s.
Dr. Villanueva is an associate professor of Medicine at Yale School of Medicine. Before coming to Yale, she founded the Ryan White-funded HIV clinic at Waterbury Hospital, and she now serves as the principal investigator for the New Haven Ryan White HIV Continuum, a collaboration between clinics and community organizations that promotes service coordination to improve quality of care for HIV patients, particularly those who are medically underserved. She works closely with community-based AIDS organizations and providers throughout Connecticut, and her research focuses on optimizing models of care that capitalize on partnerships between medical providers, public health professionals and community partners.
Titles
- Professor of Medicine (Infectious diseases)
- HIV / AIDS Care Program Director, Infectious Diseases
- Donaldson Firm Chief, Infectious Diseases
Education & Training
- FellowYale New Haven Hospital (1991)
- ResidentDuke University (1988)
- InternMichael Reese Hospital (1986)
- MDWashington University School of Medicine, Medicine (1985)
- BAHarvard College, Biochemistry (1981)
Languages Spoken
- English
- Español (Spanish)
- Tagalog
Additional Information
- Best Doctors in America: CT Magazine (2020)
- Best Doctors in America: CT Magazine (2019)
- Steven Huot Award for Dedication and Excellence: Yale University Internal Medicine Primary Care Residency Program (2019)
- George Thornton Award | Best Poster Clinical Research: CT Infectious Disease Society (CIDS) (2018)
- First Place Poster Presentation: Joseph Zaccagnino Safety and Quality Conference (2016)
- Yale Public Voices Fellowship: Yale Women’s Faculty Forum (2015)
- Emerging Leaders Program: Yale Medical Group (2015)
- Delegate: Mid-Career Women’s Faculty Professional Development, AAMC (2011)
- Johnson and Johnson International Health Fellowship: (2007)
- Waterbury Regional Chamber Health Care Council Leadership Award: (2007)
- AB of Internal Medicine, Internal Medicine (1988)
- Cllinicalinfo.HIV.gov (2023): Member
- International Journal STD and AIDS (2022): Reviewer
- American Journal of Tropical Medicine (2022): Reviewer
- Open Forum Infectious Disease (2022): Reviewer
- DHHS Guidelines for Opportunistic Infections Committee, Hepatitis C Subgroup (2020): Panel Member
- AAHIV Medicine, Subcommittee to Update Guidelines for Hep C Treatment in PWH (2020): Panel Member
- RISE (Resiliency and Sustainable Excellence at Yale) Subgroup, Updating New Faculty Orientation (2018 - 2022): Member
- Dean’s Faculty Advisory Council (2015 - 2022): Representative from ID/Geriatrics/Endocrine/Rheumatology/General Medicine
- Yale School of Management: Emerging Leaders Program (2015 - 2022): Member
- YNHH Medical Leadership Council (2015 - 2018): Member
- Victoria-Castro A, Arora T, Simonov M, Biswas A, Alausa J, Subair L, Gerber B, Nguyen A, Hsiao A, Hintz R, Yamamoto Y, Soufer R, Desir G, Wilson F, Villanueva M. Promoting Collaborative Scholarship During the COVID-19 Pandemic Through an Innovative COVID-19 Data Explorer and Repository at Yale School of Medicine: Development and Usability Study. JMIR Formative Research 2024, 8: e52120. PMID: 39226547, PMCID: PMC11408881, DOI: 10.2196/52120.
- Machavariani E, Miceli J, Altice F, Fanfair R, Speers S, Nichols L, Jenkins H, Villanueva M. Using Data-To-Care Strategies to Optimize the HIV Care Continuum in Connecticut: Results From a Randomized Controlled Trial. JAIDS Journal Of Acquired Immune Deficiency Syndromes 2024, 96: 40-50. PMID: 38324241, PMCID: PMC11009056, DOI: 10.1097/qai.0000000000003391.
- Simsek B, Zhang R, Morton C, Villanueva M. Lemierre syndrome with pulmonary empyema caused by Prevotella intermedia. BMJ Case Reports 2024, 17: e258158. PMID: 38490705, PMCID: PMC10946344, DOI: 10.1136/bcr-2023-258158.
- Elder H, Lang S, Villanueva M, John B, Roosevelt K, Altice F, Brady K, Gibson B, Buchelli M, DeMaria A, Randall L. Using the exploration, preparation, implementation, sustainment (EPIS) framework to assess the cooperative re-engagement controlled trial (CoRECT). Frontiers In Public Health 2023, 11: 1223149. PMID: 38106893, PMCID: PMC10722986, DOI: 10.3389/fpubh.2023.1223149.
- Wegener M, Brooks R, Nichols L, Villanueva M. 2510. Adapting the CDC HCV viral clearance cascade methodology for persons with HIV (PWH) and HCV co-infection in 5 Health Department Jurisdictions in the US. Open Forum Infectious Diseases 2023, 10: ofad500.2128. PMCID: PMC10678948, DOI: 10.1093/ofid/ofad500.2128.
- Wegener M, Brooks R, Nichols L, Villanueva M. 1483. Real-time Creation of HCV Treatment Cascades in Clinics to Improve HCV Treatment Rates Among Patients with HIV/HCV Co-infection. Open Forum Infectious Diseases 2023, 10: ofad500.1319. PMCID: PMC10677588, DOI: 10.1093/ofid/ofad500.1319.
- Harsono D, Deng Y, Chung S, Barakat L, Friedland G, Villanueva M, Yager J, Justen M, Edelman E. Prevalence and Correlates of Physical Inactivity Among Individuals with HIV During the First COVID-19 Wave: A Cross-sectional Survey. AIDS And Behavior 2023, 28: 1531-1545. PMID: 37824037, PMCID: PMC11349050, DOI: 10.1007/s10461-023-04170-5.
- Brooks R, Wegener M, Speers S, Nichols L, Sideleau R, Valeriano T, Buchelli M, Villanueva M. Creating a Longitudinal HCV Care Cascade for Persons With HIV/HCV Coinfection in Selected HIV Clinics Using Data to Care Methods. Health Promotion Practice 2023, 24: 1039-1049. PMID: 37439600, DOI: 10.1177/15248399231169792.
- Villanueva M. Future Directions for HIV/HCV Care: Lessons Learned From Local Evaluation Projects in Texas and Connecticut and Implications for Practice and Health Promotion. Health Promotion Practice 2023, 24: 1050-1054. PMID: 37439561, DOI: 10.1177/15248399231169919.
- Zhao A, Wegener M, Brooks R, Mininberg L, Helou E, Maughan A, Villanueva M. Characterizing Persons With HIV/HCV Coinfection Who Remain Untreated for Hepatitis C at Four HIV Clinics in Connecticut (CT): Role of Multiple Overlapping Barriers at the Individual and Clinic System Levels. Health Promotion Practice 2023, 24: 1029-1038. PMID: 37439687, DOI: 10.1177/15248399231169793.
- DiDomizio E, Chandra D, Nichols L, Villanueva M, Altice F. Challenges to Achieving HCV Micro-Elimination in People With HIV in the United States: Provider Perspectives and the Role of Implicit Bias. Health Promotion Practice 2023, 24: 998-1008. PMID: 37440258, DOI: 10.1177/15248399231169928.
- Brooks R, Wegener M, Freeman B, Fowles C, Madden L, Tetrault J, Nichols L, Altice F, Villanueva M. Improving HIV and HCV Testing in Substance Use Disorder Programs (SUDs) That Provide Medications for Opiate Use Disorder (MOUD): Role of Addressing Barriers and Implementing Universal and Site-Specific Approaches. Health Promotion Practice 2023, 24: 1018-1028. PMID: 37439759, DOI: 10.1177/15248399231169791.
- Hao R, Brooks R, Zelenev A, Spinner G, Barakat L, Villanueva M. Expanded or Risk Factor-Based Annual Screening for Hepatitis C Virus (HCV) Among Persons With HIV: Which Is the Best Approach? Health Promotion Practice 2023, 24: 1009-1017. PMID: 37439817, DOI: 10.1177/15248399231169794.
- O'Shea J, Fanfair R, Williams T, Khalil G, Brady K, DeMaria A, Villanueva M, Randall L, Jenkins H, Altice F, Camp N, Lucas C, Buchelli M, Samandari T, Weidle P. The Cooperative Re-Engagement Controlled Trial (CoRECT): Durable Viral Suppression Assessment. JAIDS Journal Of Acquired Immune Deficiency Syndromes 2023, 93: 134-142. PMID: 36812382, PMCID: PMC10962216, DOI: 10.1097/qai.0000000000003178.
- Wegener M, Brooks R, Speers S, Nichols L, Villanueva M. Implementing a Surveillance-Based Approach to Create a Statewide Viral Clearance Cascade for Hepatitis C Among People With HIV and HCV Coinfection in Connecticut. Public Health Reports 2023, 139: 208-217. PMID: 37232422, PMCID: PMC10851907, DOI: 10.1177/00333549231172173.
- Shrestha R, Fanfair R, Randall L, Lucas C, Nichols L, Camp N, Brady K, Jenkins H, Altice F, DeMaria A, Villanueva M, Weidle P. Costs and cost‐effectiveness of a collaborative data‐to‐care intervention for HIV treatment and care in the United States. Journal Of The International AIDS Society 2023, 26: e26040. PMID: 36682053, PMCID: PMC9867888, DOI: 10.1002/jia2.26040.
- Carson H, Wang K, Paek H, Hoffman P, Arakaki A, Gonzalez-Colaso R, Barakat L, Villanueva M, Womack J. Equity and use of telehealth modalities among people living with HIV during the COVID-19 pandemic. Digital Health 2023, 9: 20552076231218840. PMID: 38107977, PMCID: PMC10722925, DOI: 10.1177/20552076231218840.
- Sims K, Wegener M, Nichols L, Villanueva M. Using Learning Experience Design (LXD) to Promote Decreasing Stigma in Creating a Video Series about Syringe Services Programs (SSP). Journal Of Applied Instructional Design 2023 DOI: 10.59668/515.12966.
- Implementing a Surveillance-Based Approach to Create a Statewide Viral Clearance Cascade for Hepatitis C Among People with HIV and HCV Coinfection in ConnecticutWegener M, Brooks R, Speers S, Nichols L, Villanueva M
- The Cooperative Re-Engagement Controlled Trial (CoRECT): Durable Viral Suppression AssessmentO’Shea J, Neblett Fanfair R, Williams T, Khalil G, Brady K, DeMaria A, Villanueva M, Randall L, Jenkins H, Altice F, Camp N, Lucas C, Buchelli M, Samandari T, Weidle P
- Shrestha RK, Neblett Fanfair R, Randall L, Lucas C, Nichols L, Camp N, Brady K, Jenkins H, Altice F, Villanueva M, Demaria A
- Harsono D, Deng Y, Chung S, Barakat LA, Friedland G, Meyer JP, Porter E, Villanueva M, Wolf MS, Yager JE, Edelman EJ. Correction to: Experiences with Telemedicine for HIV Care During the COVID-19 Pandemic: A Mixed-Methods Study. AIDS And Behavior 2022, 27: 2054-2054. PMID: 36318433, PMCID: PMC9628372, DOI: 10.1007/s10461-022-03907-y.
- Brothers S, DiDomizio E, Nichols L, Brooks R, Villanueva M. Perceptions Towards HCV Treatment with Direct Acting Antivirals (DAAs): A Qualitative Analysis with Persons with HIV/HCV Co-infection Who Delay or Refuse Treatment. AIDS And Behavior 2022, 27: 119-133. PMID: 35776253, PMCID: PMC9663279, DOI: 10.1007/s10461-022-03749-8.
- Villanueva M, Miceli J, Speers S, Nichols L, Carroll C, Jenkins H, Altice F. Advancing data to care strategies for persons with HIV using an innovative reconciliation process. PLOS ONE 2022, 17: e0267903. PMID: 35511958, PMCID: PMC9071117, DOI: 10.1371/journal.pone.0267903.
- Zhao A, Rizk C, Zhao X, Esu A, Deng Y, Barakat L, Villanueva M. Longitudinal Improvements in Viral Suppression for Persons With New HIV Diagnosis Receiving Care in the Ryan White Program: A 10-Year Experience in New Haven, CT (2009–2018). Open Forum Infectious Diseases 2022, 9: ofac196. PMID: 35794946, PMCID: PMC9251657, DOI: 10.1093/ofid/ofac196.
- Tucker M, Sheikh AM, Villanueva MS. Rapidly enlarging pulmonary mass due to immune reconstitution inflammatory syndrome (IRIS) in an immunocompetent host with pulmonary Cryptococcus neoformans. BMJ Case Reports 2022, 15: e247495. PMID: 35351746, PMCID: PMC8966528, DOI: 10.1136/bcr-2021-247495.
- Sims K, Brooks R, Nichols L, Wegener M, Villanueva M. Methadone Referrals Demystified. Advances In Medical Education, Research, And Ethics 2022, 217-237. DOI: 10.4018/978-1-7998-9490-2.ch010.
- Harsono D, Deng Y, Chung S, Barakat LA, Friedland G, Meyer JP, Porter E, Villanueva M, Wolf MS, Yager JE, Edelman EJ. Experiences with Telemedicine for HIV Care During the COVID-19 Pandemic: A Mixed-Methods Study. AIDS And Behavior 2022, 26: 2099-2111. PMID: 35064390, PMCID: PMC8782707, DOI: 10.1007/s10461-021-03556-7.
- https://medicine.yale.edu/intmed/hivtraining/donaldson/curriculum/
- Sims, K. M., Brooks, R., Nichols, L., Wegener, M. D., & Villanueva, M. S. (2022). Methadone Referrals Demystified: A Client's Journey Into Methadone Treatment – Social Constructivism and the Use of Video-Based Content in Medical Provider Education. In S. Tamim (Ed.), Instructional Design Exemplars in eHealth and mHealth Education Interventions (pp. 217-237). IGI Global. https://doi.org/10.4018/978-1-7998-9490-2.ch010
- Sivakumar A, Madden L, DiDomizio E, Eller A, Villanueva M, Altice FL. Treatment of Hepatitis C virus among people who inject drugs at a syringe service program during the COVID-19 response: The potential role of telehealth, medications for opioid use disorder and minimal demands on patients. International Journal Of Drug Policy 2021, 101: 103570. PMID: 34954493, PMCID: PMC8685180, DOI: 10.1016/j.drugpo.2021.103570.
- Virata M, Villanueva M, Miceli J. 843. Targeted HIV Testing for Patients Hospitalized for COVID-19. Open Forum Infectious Diseases 2021, 8: 512-512. PMCID: PMC8643876, DOI: 10.1093/ofid/ofab466.1038.
- Virata MD, Shenoi SV, Ladines-Lim J, Villanueva MS, Barakat LA. Cumulative burden of non-communicable diseases predicts COVID hospitalization among people with HIV: A one-year retrospective cohort study. PLOS ONE 2021, 16: e0260251. PMID: 34851963, PMCID: PMC8635326, DOI: 10.1371/journal.pone.0260251.
- Fanfair R, Khalil G, Williams T, Brady K, DeMaria A, Villanueva M, Randall L, Jenkins H, Altice F, Camp N, Lucas C, Buchelli M, Samandari T, Weidle P. The Cooperative Re-Engagement Controlled trial (CoRECT): A randomised trial to assess a collaborative data to care model to improve HIV care continuum outcomes. The Lancet Regional Health - Americas 2021, 3: 100057. PMID: 36777404, PMCID: PMC9903939, DOI: 10.1016/j.lana.2021.100057.
- Werbel WA, Brown DM, Kusemiju OT, Doby BL, Seaman SM, Redd AD, Eby Y, Fernandez RE, Desai NM, Miller J, Bismut GA, Kirby CS, Schmidt HA, Clarke WA, Seisa M, Petropoulos CJ, Quinn TC, Florman SS, Huprikar S, Rana MM, Friedman-Moraco RJ, Mehta AK, Stock PG, Price JC, Stosor V, Mehta SG, Gilbert AJ, Elias N, Morris MI, Mehta SA, Small CB, Haidar G, Malinis M, Husson JS, Pereira MR, Gupta G, Hand J, Kirchner VA, Agarwal A, Aslam S, Blumberg EA, Wolfe CR, Myer K, Wood RP, Neidlinger N, Strell S, Shuck M, Wilkins H, Wadsworth M, Motter JD, Odim J, Segev DL, Durand CM, Tobian AAR, Piquant D, Link K, Hemmersbach-Miller M, Pearson T, Turgeon N, Lyon G, Kitchens W, Huckaby J, Lasseter A, Elbein R, Roberson A, Ferry E, Klock E, Cochran W, Morrison M, Rasmussen S, Bollinger J, Sugarman J, Smith A, Thomas M, Coakley M, Timpone J, Stucke A, Haydel B, Dieter R, Klein E, Neumann H, Gallon L, Goudy L, Callegari M, Marrazzo I, Jackson T, Pruett T, Farnsworth M, Locke J, Mompoint-Williams D, Basinger K, Mekeel K, Nguyen P, Kwan J, Srisengfa T, Chin-Hong P, Rogers R, Simkins J, Munoz C, Dunn T, Sawinski D, Silveira F, Hughes K, Pakstis D, Nagy J, Baldecchi M, Muthukumar T, Eddie M, Robb K, Salsgiver E, Witting B, Azar M, Villanueva M, Formica R, Tomlin R. National Landscape of Human Immunodeficiency Virus–Positive Deceased Organ Donors in the United States. Clinical Infectious Diseases 2021, 74: 2010-2019. PMID: 34453519, PMCID: PMC9187316, DOI: 10.1093/cid/ciab743.
- McPadden J, Warner F, Young HP, Hurley NC, Pulk RA, Singh A, Durant TJS, Gong G, Desai N, Haimovich A, Taylor RA, Gunel M, Dela Cruz CS, Farhadian SF, Siner J, Villanueva M, Churchwell K, Hsiao A, Torre CJ, Velazquez EJ, Herbst RS, Iwasaki A, Ko AI, Mortazavi BJ, Krumholz HM, Schulz WL. Clinical characteristics and outcomes for 7,995 patients with SARS-CoV-2 infection. PLOS ONE 2021, 16: e0243291. PMID: 33788846, PMCID: PMC8011821, DOI: 10.1371/journal.pone.0243291.
- Arora T, Simonov M, Alausa J, Subair L, Gerber B, Nguyen A, Hsiao A, Hintz R, Yamamoto Y, Soufer R, Desir G, Wilson F, Villanueva M. The Yale department of Medicine COVID-19 Data Explorer and repository (DOM-CCovX): An innovative approach to promoting collaborative scholarship during a pandemic. medRxiv, Aug 26, 2021
- Neblett Fanfair, Robyn, Khalil, George,, Williams,Tiffany, Brady, Kathleen , DeMaria, Alfred, Villanueva, Merceditas, Randall, Liisa M, Jenkins, Heidi, Altice, Frederick L., Camp, Nasima, Lucas, Crystal, Buchelli, Marianne, Samandari, Taraz, Weidle, Paul J. The Cooperative Re-engagement Controlled Trial: A Randomized Trial to Assess a Collaborative Data to Care Model to Improve HIV Care Continuum Outcomes. The Lancet Regional Health-Americas, August 28,2021.
- Virata M, Villanueva M, Shenoi S, Ladines-Lim J, Aoun-Barakat L. 543. SARS-CoV-2 Viral Dynamics For Symptomatic People Living with HIV Requiring Hospitalization For COVID-19. Open Forum Infectious Diseases 2020, 7: s338-s338. PMCID: PMC7777445, DOI: 10.1093/ofid/ofaa439.737.
- Price CC, Altice FL, Shyr Y, Koff A, Pischel L, Goshua G, Azar MM, Mcmanus D, Chen SC, Gleeson SE, Britto CJ, Azmy V, Kaman K, Gaston DC, Davis M, Burrello T, Harris Z, Villanueva MS, Aoun-Barakat L, Kang I, Seropian S, Chupp G, Bucala R, Kaminski N, Lee AI, LoRusso PM, Topal JE, Dela Cruz C, Malinis M. Tocilizumab Treatment for Cytokine Release Syndrome in Hospitalized Patients With Coronavirus Disease 2019 Survival and Clinical Outcomes. CHEST Journal 2020, 158: 1397-1408. PMID: 32553536, PMCID: PMC7831876, DOI: 10.1016/j.chest.2020.06.006.
- Edelman EJ, Aoun-Barakat L, Villanueva M, Friedland G. Confronting Another Pandemic: Lessons from HIV can Inform Our COVID-19 Response. AIDS And Behavior 2020, 24: 1977-1979. PMID: 32399798, PMCID: PMC7215127, DOI: 10.1007/s10461-020-02908-z.
- Adamson PC, Miceli J, Shiferaw B, Villanueva MS, Canterino JE. A Colocalized Hepatitis C Virus Clinic in a Primary Care Practice Improves Linkage to Care in a High Prevalence Population. The American Journal Of Medicine 2020, 133: 705-712. PMID: 31987799, DOI: 10.1016/j.amjmed.2019.12.028.
- https://aetcct.org
- https://aetcct.org/connquer-hepc/
- Neblett Fanfair R, Shrestha RK, Randall L, Lucas C, Nichols L, Camp NM, Brady K, Jenkins H, Altice F, Villanueva M, DeMaria A. Implementing Data to Care-What Are the Costs for the Health Department? JAIDS Journal Of Acquired Immune Deficiency Syndromes 2019, 82 Suppl 1: s57-s61. PMID: 31425397, DOI: 10.1097/qai.0000000000001968.
- Rizk C, Miceli J, Shiferaw B, Malinis M, Barakat L, Ogbuagu O, Villanueva M. Implementing a Comprehensive Hepatitis C Virus (HCV) Clinic Within a Human Immunodeficiency Virus Clinic: A Model of Care for HCV Microelimination. Open Forum Infectious Diseases 2019, 6: ofz361. PMID: 31412130, PMCID: PMC6785669, DOI: 10.1093/ofid/ofz361.
- Oldfield B, Muñoz N, McGovern M, Funaro M, Villanueva M, Tetrault J, Edelman E. Integration of care for HIV and opioid use disorder. AIDS 2019, Publish Ahead of Print: &na;. PMID: 30882491, PMCID: PMC6588508, DOI: 10.1097/qad.0000000000002125.
- Oldfield BJ, Muñoz N, Boshnack N, Leavitt R, McGovern MP, Villanueva M, Tetrault JM, Edelman E. “No more falling through the cracks”: A qualitative study to inform measurement of integration of care of HIV and opioid use disorder. Journal Of Substance Use And Addiction Treatment 2018, 97: 28-40. PMID: 30577897, DOI: 10.1016/j.jsat.2018.11.007.
- Haque L, Villanueva M, Russo A, Yuan Y, Lee EJ, Topal J, Podoltsev N. A rare case of visceral leishmaniasis in an immunocompetent traveler returning to the United States from Europe. PLOS Neglected Tropical Diseases 2018, 12: e0006727. PMID: 30286207, PMCID: PMC6171829, DOI: 10.1371/journal.pntd.0006727.
- Robledo-Gil T, Harada K, Ikuta I, Villanueva M. Paradoxical Reaction in a Patient with Co-Occurring Tuberculous Meningitis and Pott’s Disease. American Journal Of Case Reports 2018, 19: 699-704. PMID: 29907737, PMCID: PMC6034555, DOI: 10.12659/ajcr.909194.
- Bandaranayake TD, Ogbuagu OE, Mahajan A, Vortmeyer AO, Villanueva MS. Fatal cryptococcal meningitis in an AIDS patient complicated with immune reconstitution syndrome refractory to prolonged amphotericin B treatment. International Journal Of STD & AIDS 2018, 29: 1250-1254. PMID: 29749873, DOI: 10.1177/0956462418773219.
- Ogbuagu O, Hao R, Virata M, Villanueva M, Malinis M. Efficacy of an 8-week course of sofosbuvir and ledipasvir for the treatment of HCV infection in selected HIV-infected patients. F1000Research 2017, 6: 620. DOI: 10.12688/f1000research.11397.1.
- Villanueva MS and Friedland G. Responding to an Ever-Changing Epidemic: The History of HIV/AIDS Care in New Haven. CT Medicine 2017; 81(4): 237-40
- Azar MM, Malinis MF, Moss J, Formica RN, Villanueva MS. Integrase strand transferase inhibitors: the preferred antiretroviral regimen in HIV-positive renal transplantation. International Journal Of STD & AIDS 2016, 28: 447-458. PMID: 27193421, DOI: 10.1177/0956462416651528.
- Yamahiro A, Lau KH, Peaper DR, Villanueva M. Meningitis Caused by Candida Dubliniensis in a Patient with Cirrhosis: A Case Report and Review of the Literature. Mycopathologia 2016, 181: 589-593. PMID: 27038312, DOI: 10.1007/s11046-016-0006-7.
- Trends in Tuberculosis Cases at a Connecticut Hospital, 2005–2014Yuh T, Ogbuagu O, Villanueva M, Shenoi S. Trends in tuberculosis cases at a Connecticut Hospital 2005-2014. Open Forum Infectious Diseases 2015; (2) suppl 1), December 2015, 566 https://doi.org/10.1093/ofid/ofv133.440
- Pamer EG, Sijts AJ, Villanueva MS, Busch DH, Vijh S. MHC class I antigen processing of Listeria monocytogenes proteins: implications for dominant and subdominant CTL responses. Immunological Reviews 1997, 158: 129-36. PMID: 9314081, DOI: 10.1111/j.1600-065x.1997.tb00999.x.
- Sijts AJ, Villanueva MS, Pamer EG. CTL epitope generation is tightly linked to cellular proteolysis of a Listeria monocytogenes antigen. Journal Of Immunology (Baltimore, Md. : 1950) 1996, 156: 1497-503. PMID: 8568253.
- Villanueva MS, Sijts AJ, Pamer EG. Listeriolysin is processed efficiently into an MHC class I-associated epitope in Listeria monocytogenes-infected cells. Journal Of Immunology (Baltimore, Md. : 1950) 1995, 155: 5227-33. PMID: 7594534.
- Villanueva MS, Beckers CJ, Pamer EG. Infection with Listeria monocytogenes impairs sialic acid addition to host cell glycoproteins. The Journal Of Experimental Medicine 1994, 180: 2137-45. PMID: 7964488, PMCID: PMC2191782, DOI: 10.1084/jem.180.6.2137.
- Villanueva MS, Fischer P, Feen K, Pamer EG. Efficiency of MHC class I antigen processing: a quantitative analysis. Immunity 1994, 1: 479-89. PMID: 7534616, DOI: 10.1016/1074-7613(94)90090-6.
- Yale Center for Infectious Disease200 Orchard StreetNew Haven, CT 06511
- Yale Infectious DiseasesYale New Haven Hospital20 York StreetNew Haven, CT 06510
Biography
Merceditas S. Villanueva, MD, director of the Yale Medicine AIDS Care Program, is an infectious disease specialist with a clinical focus on HIV and AIDS. She cares for patients in the hospital who are sick with various infections, as well as those with complications of HIV. She also treats patients in the Nathan Smith Clinic, where she primarily treats HIV.
As a clinician, Dr. Villanueva believes in getting to know each patient as an individual. “I think that way you really make a difference in people's lives,” she says. “Sometimes we think it has to be this huge thing that you do for people. But it's the little things that you notice that will make a difference—the ability to hear them, the ability to link them to the right resources if they need it.” People living with HIV have different needs that require resources beyond strict medical care, she says. “A team approach including community-based partners is essential.”
Dr. Villanueva was drawn to the field of infectious diseases after traveling to different countries with her father, who worked for the United Nations. She saw many people who struggled with diseases that called for medical care within the context of global public health concerns. “I always felt that it would be great to make an impact in those communities,” Dr. Villanueva says. The field of HIV pulled all those interests together.
AIDS was a uniformly fatal disease when Dr. Villanueva was a medical student in the early 1980s. In the last two to three decades, increasingly better treatments have made HIV a chronic disease. “The message that we gave patients in the early days was, ‘Let's try to make your remaining days as comfortable as possible.’ But that message has totally changed. HIV is not curable, but as long as people take their medications, it’s controllable, so people living with HIV can lead, more or less, normal lives.” As such, doctors and researchers are turning their attention to people with HIV who are surviving into their 50s and 60s.
Dr. Villanueva is an associate professor of Medicine at Yale School of Medicine. Before coming to Yale, she founded the Ryan White-funded HIV clinic at Waterbury Hospital, and she now serves as the principal investigator for the New Haven Ryan White HIV Continuum, a collaboration between clinics and community organizations that promotes service coordination to improve quality of care for HIV patients, particularly those who are medically underserved. She works closely with community-based AIDS organizations and providers throughout Connecticut, and her research focuses on optimizing models of care that capitalize on partnerships between medical providers, public health professionals and community partners.
Titles
- Professor of Medicine (Infectious diseases)
- HIV / AIDS Care Program Director, Infectious Diseases
- Donaldson Firm Chief, Infectious Diseases
Education & Training
- FellowYale New Haven Hospital (1991)
- ResidentDuke University (1988)
- InternMichael Reese Hospital (1986)
- MDWashington University School of Medicine, Medicine (1985)
- BAHarvard College, Biochemistry (1981)
Languages Spoken
- English
- Español (Spanish)
- Tagalog
Additional Information
- Best Doctors in America: CT Magazine (2020)
- Best Doctors in America: CT Magazine (2019)
- Steven Huot Award for Dedication and Excellence: Yale University Internal Medicine Primary Care Residency Program (2019)
- George Thornton Award | Best Poster Clinical Research: CT Infectious Disease Society (CIDS) (2018)
- First Place Poster Presentation: Joseph Zaccagnino Safety and Quality Conference (2016)
- Yale Public Voices Fellowship: Yale Women’s Faculty Forum (2015)
- Emerging Leaders Program: Yale Medical Group (2015)
- Delegate: Mid-Career Women’s Faculty Professional Development, AAMC (2011)
- Johnson and Johnson International Health Fellowship: (2007)
- Waterbury Regional Chamber Health Care Council Leadership Award: (2007)
- AB of Internal Medicine, Internal Medicine (1988)
- Cllinicalinfo.HIV.gov (2023): Member
- International Journal STD and AIDS (2022): Reviewer
- American Journal of Tropical Medicine (2022): Reviewer
- Open Forum Infectious Disease (2022): Reviewer
- DHHS Guidelines for Opportunistic Infections Committee, Hepatitis C Subgroup (2020): Panel Member
- AAHIV Medicine, Subcommittee to Update Guidelines for Hep C Treatment in PWH (2020): Panel Member
- RISE (Resiliency and Sustainable Excellence at Yale) Subgroup, Updating New Faculty Orientation (2018 - 2022): Member
- Dean’s Faculty Advisory Council (2015 - 2022): Representative from ID/Geriatrics/Endocrine/Rheumatology/General Medicine
- Yale School of Management: Emerging Leaders Program (2015 - 2022): Member
- YNHH Medical Leadership Council (2015 - 2018): Member
- Victoria-Castro A, Arora T, Simonov M, Biswas A, Alausa J, Subair L, Gerber B, Nguyen A, Hsiao A, Hintz R, Yamamoto Y, Soufer R, Desir G, Wilson F, Villanueva M. Promoting Collaborative Scholarship During the COVID-19 Pandemic Through an Innovative COVID-19 Data Explorer and Repository at Yale School of Medicine: Development and Usability Study. JMIR Formative Research 2024, 8: e52120. PMID: 39226547, PMCID: PMC11408881, DOI: 10.2196/52120.
- Machavariani E, Miceli J, Altice F, Fanfair R, Speers S, Nichols L, Jenkins H, Villanueva M. Using Data-To-Care Strategies to Optimize the HIV Care Continuum in Connecticut: Results From a Randomized Controlled Trial. JAIDS Journal Of Acquired Immune Deficiency Syndromes 2024, 96: 40-50. PMID: 38324241, PMCID: PMC11009056, DOI: 10.1097/qai.0000000000003391.
- Simsek B, Zhang R, Morton C, Villanueva M. Lemierre syndrome with pulmonary empyema caused by Prevotella intermedia. BMJ Case Reports 2024, 17: e258158. PMID: 38490705, PMCID: PMC10946344, DOI: 10.1136/bcr-2023-258158.
- Elder H, Lang S, Villanueva M, John B, Roosevelt K, Altice F, Brady K, Gibson B, Buchelli M, DeMaria A, Randall L. Using the exploration, preparation, implementation, sustainment (EPIS) framework to assess the cooperative re-engagement controlled trial (CoRECT). Frontiers In Public Health 2023, 11: 1223149. PMID: 38106893, PMCID: PMC10722986, DOI: 10.3389/fpubh.2023.1223149.
- Wegener M, Brooks R, Nichols L, Villanueva M. 2510. Adapting the CDC HCV viral clearance cascade methodology for persons with HIV (PWH) and HCV co-infection in 5 Health Department Jurisdictions in the US. Open Forum Infectious Diseases 2023, 10: ofad500.2128. PMCID: PMC10678948, DOI: 10.1093/ofid/ofad500.2128.
- Wegener M, Brooks R, Nichols L, Villanueva M. 1483. Real-time Creation of HCV Treatment Cascades in Clinics to Improve HCV Treatment Rates Among Patients with HIV/HCV Co-infection. Open Forum Infectious Diseases 2023, 10: ofad500.1319. PMCID: PMC10677588, DOI: 10.1093/ofid/ofad500.1319.
- Harsono D, Deng Y, Chung S, Barakat L, Friedland G, Villanueva M, Yager J, Justen M, Edelman E. Prevalence and Correlates of Physical Inactivity Among Individuals with HIV During the First COVID-19 Wave: A Cross-sectional Survey. AIDS And Behavior 2023, 28: 1531-1545. PMID: 37824037, PMCID: PMC11349050, DOI: 10.1007/s10461-023-04170-5.
- Brooks R, Wegener M, Speers S, Nichols L, Sideleau R, Valeriano T, Buchelli M, Villanueva M. Creating a Longitudinal HCV Care Cascade for Persons With HIV/HCV Coinfection in Selected HIV Clinics Using Data to Care Methods. Health Promotion Practice 2023, 24: 1039-1049. PMID: 37439600, DOI: 10.1177/15248399231169792.
- Villanueva M. Future Directions for HIV/HCV Care: Lessons Learned From Local Evaluation Projects in Texas and Connecticut and Implications for Practice and Health Promotion. Health Promotion Practice 2023, 24: 1050-1054. PMID: 37439561, DOI: 10.1177/15248399231169919.
- Zhao A, Wegener M, Brooks R, Mininberg L, Helou E, Maughan A, Villanueva M. Characterizing Persons With HIV/HCV Coinfection Who Remain Untreated for Hepatitis C at Four HIV Clinics in Connecticut (CT): Role of Multiple Overlapping Barriers at the Individual and Clinic System Levels. Health Promotion Practice 2023, 24: 1029-1038. PMID: 37439687, DOI: 10.1177/15248399231169793.
- DiDomizio E, Chandra D, Nichols L, Villanueva M, Altice F. Challenges to Achieving HCV Micro-Elimination in People With HIV in the United States: Provider Perspectives and the Role of Implicit Bias. Health Promotion Practice 2023, 24: 998-1008. PMID: 37440258, DOI: 10.1177/15248399231169928.
- Brooks R, Wegener M, Freeman B, Fowles C, Madden L, Tetrault J, Nichols L, Altice F, Villanueva M. Improving HIV and HCV Testing in Substance Use Disorder Programs (SUDs) That Provide Medications for Opiate Use Disorder (MOUD): Role of Addressing Barriers and Implementing Universal and Site-Specific Approaches. Health Promotion Practice 2023, 24: 1018-1028. PMID: 37439759, DOI: 10.1177/15248399231169791.
- Hao R, Brooks R, Zelenev A, Spinner G, Barakat L, Villanueva M. Expanded or Risk Factor-Based Annual Screening for Hepatitis C Virus (HCV) Among Persons With HIV: Which Is the Best Approach? Health Promotion Practice 2023, 24: 1009-1017. PMID: 37439817, DOI: 10.1177/15248399231169794.
- O'Shea J, Fanfair R, Williams T, Khalil G, Brady K, DeMaria A, Villanueva M, Randall L, Jenkins H, Altice F, Camp N, Lucas C, Buchelli M, Samandari T, Weidle P. The Cooperative Re-Engagement Controlled Trial (CoRECT): Durable Viral Suppression Assessment. JAIDS Journal Of Acquired Immune Deficiency Syndromes 2023, 93: 134-142. PMID: 36812382, PMCID: PMC10962216, DOI: 10.1097/qai.0000000000003178.
- Wegener M, Brooks R, Speers S, Nichols L, Villanueva M. Implementing a Surveillance-Based Approach to Create a Statewide Viral Clearance Cascade for Hepatitis C Among People With HIV and HCV Coinfection in Connecticut. Public Health Reports 2023, 139: 208-217. PMID: 37232422, PMCID: PMC10851907, DOI: 10.1177/00333549231172173.
- Shrestha R, Fanfair R, Randall L, Lucas C, Nichols L, Camp N, Brady K, Jenkins H, Altice F, DeMaria A, Villanueva M, Weidle P. Costs and cost‐effectiveness of a collaborative data‐to‐care intervention for HIV treatment and care in the United States. Journal Of The International AIDS Society 2023, 26: e26040. PMID: 36682053, PMCID: PMC9867888, DOI: 10.1002/jia2.26040.
- Carson H, Wang K, Paek H, Hoffman P, Arakaki A, Gonzalez-Colaso R, Barakat L, Villanueva M, Womack J. Equity and use of telehealth modalities among people living with HIV during the COVID-19 pandemic. Digital Health 2023, 9: 20552076231218840. PMID: 38107977, PMCID: PMC10722925, DOI: 10.1177/20552076231218840.
- Sims K, Wegener M, Nichols L, Villanueva M. Using Learning Experience Design (LXD) to Promote Decreasing Stigma in Creating a Video Series about Syringe Services Programs (SSP). Journal Of Applied Instructional Design 2023 DOI: 10.59668/515.12966.
- Implementing a Surveillance-Based Approach to Create a Statewide Viral Clearance Cascade for Hepatitis C Among People with HIV and HCV Coinfection in ConnecticutWegener M, Brooks R, Speers S, Nichols L, Villanueva M
- The Cooperative Re-Engagement Controlled Trial (CoRECT): Durable Viral Suppression AssessmentO’Shea J, Neblett Fanfair R, Williams T, Khalil G, Brady K, DeMaria A, Villanueva M, Randall L, Jenkins H, Altice F, Camp N, Lucas C, Buchelli M, Samandari T, Weidle P
- Shrestha RK, Neblett Fanfair R, Randall L, Lucas C, Nichols L, Camp N, Brady K, Jenkins H, Altice F, Villanueva M, Demaria A
- Harsono D, Deng Y, Chung S, Barakat LA, Friedland G, Meyer JP, Porter E, Villanueva M, Wolf MS, Yager JE, Edelman EJ. Correction to: Experiences with Telemedicine for HIV Care During the COVID-19 Pandemic: A Mixed-Methods Study. AIDS And Behavior 2022, 27: 2054-2054. PMID: 36318433, PMCID: PMC9628372, DOI: 10.1007/s10461-022-03907-y.
- Brothers S, DiDomizio E, Nichols L, Brooks R, Villanueva M. Perceptions Towards HCV Treatment with Direct Acting Antivirals (DAAs): A Qualitative Analysis with Persons with HIV/HCV Co-infection Who Delay or Refuse Treatment. AIDS And Behavior 2022, 27: 119-133. PMID: 35776253, PMCID: PMC9663279, DOI: 10.1007/s10461-022-03749-8.
- Villanueva M, Miceli J, Speers S, Nichols L, Carroll C, Jenkins H, Altice F. Advancing data to care strategies for persons with HIV using an innovative reconciliation process. PLOS ONE 2022, 17: e0267903. PMID: 35511958, PMCID: PMC9071117, DOI: 10.1371/journal.pone.0267903.
- Zhao A, Rizk C, Zhao X, Esu A, Deng Y, Barakat L, Villanueva M. Longitudinal Improvements in Viral Suppression for Persons With New HIV Diagnosis Receiving Care in the Ryan White Program: A 10-Year Experience in New Haven, CT (2009–2018). Open Forum Infectious Diseases 2022, 9: ofac196. PMID: 35794946, PMCID: PMC9251657, DOI: 10.1093/ofid/ofac196.
- Tucker M, Sheikh AM, Villanueva MS. Rapidly enlarging pulmonary mass due to immune reconstitution inflammatory syndrome (IRIS) in an immunocompetent host with pulmonary Cryptococcus neoformans. BMJ Case Reports 2022, 15: e247495. PMID: 35351746, PMCID: PMC8966528, DOI: 10.1136/bcr-2021-247495.
- Sims K, Brooks R, Nichols L, Wegener M, Villanueva M. Methadone Referrals Demystified. Advances In Medical Education, Research, And Ethics 2022, 217-237. DOI: 10.4018/978-1-7998-9490-2.ch010.
- Harsono D, Deng Y, Chung S, Barakat LA, Friedland G, Meyer JP, Porter E, Villanueva M, Wolf MS, Yager JE, Edelman EJ. Experiences with Telemedicine for HIV Care During the COVID-19 Pandemic: A Mixed-Methods Study. AIDS And Behavior 2022, 26: 2099-2111. PMID: 35064390, PMCID: PMC8782707, DOI: 10.1007/s10461-021-03556-7.
- https://medicine.yale.edu/intmed/hivtraining/donaldson/curriculum/
- Sims, K. M., Brooks, R., Nichols, L., Wegener, M. D., & Villanueva, M. S. (2022). Methadone Referrals Demystified: A Client's Journey Into Methadone Treatment – Social Constructivism and the Use of Video-Based Content in Medical Provider Education. In S. Tamim (Ed.), Instructional Design Exemplars in eHealth and mHealth Education Interventions (pp. 217-237). IGI Global. https://doi.org/10.4018/978-1-7998-9490-2.ch010
- Sivakumar A, Madden L, DiDomizio E, Eller A, Villanueva M, Altice FL. Treatment of Hepatitis C virus among people who inject drugs at a syringe service program during the COVID-19 response: The potential role of telehealth, medications for opioid use disorder and minimal demands on patients. International Journal Of Drug Policy 2021, 101: 103570. PMID: 34954493, PMCID: PMC8685180, DOI: 10.1016/j.drugpo.2021.103570.
- Virata M, Villanueva M, Miceli J. 843. Targeted HIV Testing for Patients Hospitalized for COVID-19. Open Forum Infectious Diseases 2021, 8: 512-512. PMCID: PMC8643876, DOI: 10.1093/ofid/ofab466.1038.
- Virata MD, Shenoi SV, Ladines-Lim J, Villanueva MS, Barakat LA. Cumulative burden of non-communicable diseases predicts COVID hospitalization among people with HIV: A one-year retrospective cohort study. PLOS ONE 2021, 16: e0260251. PMID: 34851963, PMCID: PMC8635326, DOI: 10.1371/journal.pone.0260251.
- Fanfair R, Khalil G, Williams T, Brady K, DeMaria A, Villanueva M, Randall L, Jenkins H, Altice F, Camp N, Lucas C, Buchelli M, Samandari T, Weidle P. The Cooperative Re-Engagement Controlled trial (CoRECT): A randomised trial to assess a collaborative data to care model to improve HIV care continuum outcomes. The Lancet Regional Health - Americas 2021, 3: 100057. PMID: 36777404, PMCID: PMC9903939, DOI: 10.1016/j.lana.2021.100057.
- Werbel WA, Brown DM, Kusemiju OT, Doby BL, Seaman SM, Redd AD, Eby Y, Fernandez RE, Desai NM, Miller J, Bismut GA, Kirby CS, Schmidt HA, Clarke WA, Seisa M, Petropoulos CJ, Quinn TC, Florman SS, Huprikar S, Rana MM, Friedman-Moraco RJ, Mehta AK, Stock PG, Price JC, Stosor V, Mehta SG, Gilbert AJ, Elias N, Morris MI, Mehta SA, Small CB, Haidar G, Malinis M, Husson JS, Pereira MR, Gupta G, Hand J, Kirchner VA, Agarwal A, Aslam S, Blumberg EA, Wolfe CR, Myer K, Wood RP, Neidlinger N, Strell S, Shuck M, Wilkins H, Wadsworth M, Motter JD, Odim J, Segev DL, Durand CM, Tobian AAR, Piquant D, Link K, Hemmersbach-Miller M, Pearson T, Turgeon N, Lyon G, Kitchens W, Huckaby J, Lasseter A, Elbein R, Roberson A, Ferry E, Klock E, Cochran W, Morrison M, Rasmussen S, Bollinger J, Sugarman J, Smith A, Thomas M, Coakley M, Timpone J, Stucke A, Haydel B, Dieter R, Klein E, Neumann H, Gallon L, Goudy L, Callegari M, Marrazzo I, Jackson T, Pruett T, Farnsworth M, Locke J, Mompoint-Williams D, Basinger K, Mekeel K, Nguyen P, Kwan J, Srisengfa T, Chin-Hong P, Rogers R, Simkins J, Munoz C, Dunn T, Sawinski D, Silveira F, Hughes K, Pakstis D, Nagy J, Baldecchi M, Muthukumar T, Eddie M, Robb K, Salsgiver E, Witting B, Azar M, Villanueva M, Formica R, Tomlin R. National Landscape of Human Immunodeficiency Virus–Positive Deceased Organ Donors in the United States. Clinical Infectious Diseases 2021, 74: 2010-2019. PMID: 34453519, PMCID: PMC9187316, DOI: 10.1093/cid/ciab743.
- McPadden J, Warner F, Young HP, Hurley NC, Pulk RA, Singh A, Durant TJS, Gong G, Desai N, Haimovich A, Taylor RA, Gunel M, Dela Cruz CS, Farhadian SF, Siner J, Villanueva M, Churchwell K, Hsiao A, Torre CJ, Velazquez EJ, Herbst RS, Iwasaki A, Ko AI, Mortazavi BJ, Krumholz HM, Schulz WL. Clinical characteristics and outcomes for 7,995 patients with SARS-CoV-2 infection. PLOS ONE 2021, 16: e0243291. PMID: 33788846, PMCID: PMC8011821, DOI: 10.1371/journal.pone.0243291.
- Arora T, Simonov M, Alausa J, Subair L, Gerber B, Nguyen A, Hsiao A, Hintz R, Yamamoto Y, Soufer R, Desir G, Wilson F, Villanueva M. The Yale department of Medicine COVID-19 Data Explorer and repository (DOM-CCovX): An innovative approach to promoting collaborative scholarship during a pandemic. medRxiv, Aug 26, 2021
- Neblett Fanfair, Robyn, Khalil, George,, Williams,Tiffany, Brady, Kathleen , DeMaria, Alfred, Villanueva, Merceditas, Randall, Liisa M, Jenkins, Heidi, Altice, Frederick L., Camp, Nasima, Lucas, Crystal, Buchelli, Marianne, Samandari, Taraz, Weidle, Paul J. The Cooperative Re-engagement Controlled Trial: A Randomized Trial to Assess a Collaborative Data to Care Model to Improve HIV Care Continuum Outcomes. The Lancet Regional Health-Americas, August 28,2021.
- Virata M, Villanueva M, Shenoi S, Ladines-Lim J, Aoun-Barakat L. 543. SARS-CoV-2 Viral Dynamics For Symptomatic People Living with HIV Requiring Hospitalization For COVID-19. Open Forum Infectious Diseases 2020, 7: s338-s338. PMCID: PMC7777445, DOI: 10.1093/ofid/ofaa439.737.
- Price CC, Altice FL, Shyr Y, Koff A, Pischel L, Goshua G, Azar MM, Mcmanus D, Chen SC, Gleeson SE, Britto CJ, Azmy V, Kaman K, Gaston DC, Davis M, Burrello T, Harris Z, Villanueva MS, Aoun-Barakat L, Kang I, Seropian S, Chupp G, Bucala R, Kaminski N, Lee AI, LoRusso PM, Topal JE, Dela Cruz C, Malinis M. Tocilizumab Treatment for Cytokine Release Syndrome in Hospitalized Patients With Coronavirus Disease 2019 Survival and Clinical Outcomes. CHEST Journal 2020, 158: 1397-1408. PMID: 32553536, PMCID: PMC7831876, DOI: 10.1016/j.chest.2020.06.006.
- Edelman EJ, Aoun-Barakat L, Villanueva M, Friedland G. Confronting Another Pandemic: Lessons from HIV can Inform Our COVID-19 Response. AIDS And Behavior 2020, 24: 1977-1979. PMID: 32399798, PMCID: PMC7215127, DOI: 10.1007/s10461-020-02908-z.
- Adamson PC, Miceli J, Shiferaw B, Villanueva MS, Canterino JE. A Colocalized Hepatitis C Virus Clinic in a Primary Care Practice Improves Linkage to Care in a High Prevalence Population. The American Journal Of Medicine 2020, 133: 705-712. PMID: 31987799, DOI: 10.1016/j.amjmed.2019.12.028.
- https://aetcct.org
- https://aetcct.org/connquer-hepc/
- Neblett Fanfair R, Shrestha RK, Randall L, Lucas C, Nichols L, Camp NM, Brady K, Jenkins H, Altice F, Villanueva M, DeMaria A. Implementing Data to Care-What Are the Costs for the Health Department? JAIDS Journal Of Acquired Immune Deficiency Syndromes 2019, 82 Suppl 1: s57-s61. PMID: 31425397, DOI: 10.1097/qai.0000000000001968.
- Rizk C, Miceli J, Shiferaw B, Malinis M, Barakat L, Ogbuagu O, Villanueva M. Implementing a Comprehensive Hepatitis C Virus (HCV) Clinic Within a Human Immunodeficiency Virus Clinic: A Model of Care for HCV Microelimination. Open Forum Infectious Diseases 2019, 6: ofz361. PMID: 31412130, PMCID: PMC6785669, DOI: 10.1093/ofid/ofz361.
- Oldfield B, Muñoz N, McGovern M, Funaro M, Villanueva M, Tetrault J, Edelman E. Integration of care for HIV and opioid use disorder. AIDS 2019, Publish Ahead of Print: &na;. PMID: 30882491, PMCID: PMC6588508, DOI: 10.1097/qad.0000000000002125.
- Oldfield BJ, Muñoz N, Boshnack N, Leavitt R, McGovern MP, Villanueva M, Tetrault JM, Edelman E. “No more falling through the cracks”: A qualitative study to inform measurement of integration of care of HIV and opioid use disorder. Journal Of Substance Use And Addiction Treatment 2018, 97: 28-40. PMID: 30577897, DOI: 10.1016/j.jsat.2018.11.007.
- Haque L, Villanueva M, Russo A, Yuan Y, Lee EJ, Topal J, Podoltsev N. A rare case of visceral leishmaniasis in an immunocompetent traveler returning to the United States from Europe. PLOS Neglected Tropical Diseases 2018, 12: e0006727. PMID: 30286207, PMCID: PMC6171829, DOI: 10.1371/journal.pntd.0006727.
- Robledo-Gil T, Harada K, Ikuta I, Villanueva M. Paradoxical Reaction in a Patient with Co-Occurring Tuberculous Meningitis and Pott’s Disease. American Journal Of Case Reports 2018, 19: 699-704. PMID: 29907737, PMCID: PMC6034555, DOI: 10.12659/ajcr.909194.
- Bandaranayake TD, Ogbuagu OE, Mahajan A, Vortmeyer AO, Villanueva MS. Fatal cryptococcal meningitis in an AIDS patient complicated with immune reconstitution syndrome refractory to prolonged amphotericin B treatment. International Journal Of STD & AIDS 2018, 29: 1250-1254. PMID: 29749873, DOI: 10.1177/0956462418773219.
- Ogbuagu O, Hao R, Virata M, Villanueva M, Malinis M. Efficacy of an 8-week course of sofosbuvir and ledipasvir for the treatment of HCV infection in selected HIV-infected patients. F1000Research 2017, 6: 620. DOI: 10.12688/f1000research.11397.1.
- Villanueva MS and Friedland G. Responding to an Ever-Changing Epidemic: The History of HIV/AIDS Care in New Haven. CT Medicine 2017; 81(4): 237-40
- Azar MM, Malinis MF, Moss J, Formica RN, Villanueva MS. Integrase strand transferase inhibitors: the preferred antiretroviral regimen in HIV-positive renal transplantation. International Journal Of STD & AIDS 2016, 28: 447-458. PMID: 27193421, DOI: 10.1177/0956462416651528.
- Yamahiro A, Lau KH, Peaper DR, Villanueva M. Meningitis Caused by Candida Dubliniensis in a Patient with Cirrhosis: A Case Report and Review of the Literature. Mycopathologia 2016, 181: 589-593. PMID: 27038312, DOI: 10.1007/s11046-016-0006-7.
- Trends in Tuberculosis Cases at a Connecticut Hospital, 2005–2014Yuh T, Ogbuagu O, Villanueva M, Shenoi S. Trends in tuberculosis cases at a Connecticut Hospital 2005-2014. Open Forum Infectious Diseases 2015; (2) suppl 1), December 2015, 566 https://doi.org/10.1093/ofid/ofv133.440
- Pamer EG, Sijts AJ, Villanueva MS, Busch DH, Vijh S. MHC class I antigen processing of Listeria monocytogenes proteins: implications for dominant and subdominant CTL responses. Immunological Reviews 1997, 158: 129-36. PMID: 9314081, DOI: 10.1111/j.1600-065x.1997.tb00999.x.
- Sijts AJ, Villanueva MS, Pamer EG. CTL epitope generation is tightly linked to cellular proteolysis of a Listeria monocytogenes antigen. Journal Of Immunology (Baltimore, Md. : 1950) 1996, 156: 1497-503. PMID: 8568253.
- Villanueva MS, Sijts AJ, Pamer EG. Listeriolysin is processed efficiently into an MHC class I-associated epitope in Listeria monocytogenes-infected cells. Journal Of Immunology (Baltimore, Md. : 1950) 1995, 155: 5227-33. PMID: 7594534.
- Villanueva MS, Beckers CJ, Pamer EG. Infection with Listeria monocytogenes impairs sialic acid addition to host cell glycoproteins. The Journal Of Experimental Medicine 1994, 180: 2137-45. PMID: 7964488, PMCID: PMC2191782, DOI: 10.1084/jem.180.6.2137.
- Villanueva MS, Fischer P, Feen K, Pamer EG. Efficiency of MHC class I antigen processing: a quantitative analysis. Immunity 1994, 1: 479-89. PMID: 7534616, DOI: 10.1016/1074-7613(94)90090-6.
- Yale Center for Infectious Disease200 Orchard StreetNew Haven, CT 06511
- Yale Infectious DiseasesYale New Haven Hospital20 York StreetNew Haven, CT 06510
- Yale Center for Infectious Disease200 Orchard StreetNew Haven, CT 06511
- Yale Infectious DiseasesYale New Haven Hospital20 York StreetNew Haven, CT 06510