- Yale Dermatology BranfordYale Dermatology - Branford322 East Main Street, Ste Suite 2GBranford, CT 06405
Matthew Vesely, MD, PhD
Biography
Matthew Vesely, MD, is a dermatologist who treats psoriasis, eczema, and other autoimmune skin disorders. Dr. Vesely also sees patients with chronic skin diseases, including discoid lupus erythematosus (DLE) and hidradenitis suppurativa (HS).
“Seeing patients who have been suffering from inflammatory skin diseases for years finally get relief with the help of a targeted therapy is very rewarding,” he says.
Dr. Vesely says he enjoys working with patients and their families to find the best approach to treat a skin disorder. “I always explain that even if the first set of therapies are ineffective, we won't stop until we find the most effective treatment plan,” he says.
Dr. Vesely says he chose his specialty after learning that a large number of skin diseases caused by an overactive immune system lack FDA-approved treatments. In his research, Dr. Vesely investigates emerging new therapies that could potentially help his patients.
“Being able to research the same diseases I treat is extremely gratifying and motivating,” Dr. Vesely says.
Titles
- Assistant Professor of Dermatology
Education & Training
- ResidentYale School of Medicine (Dermatology) (2014-2017) (2017)
- InternBarnes Jewish Hospital (St. Louis) (2013-2014) (2014)
- PhDWashington University School of Medicine, St. Louis, Immunology (2013)
- MDWashington University School of Medicine (2013)
- BSCreighton University, Biology, Theology, History (2003)
Additional Information
- Dermatology Fellows Award: Melanoma Research Alliance (2019)
- Physician-Scientist Career Development Award: Dermatology Foundation (2019)
- YCCI Research Scholar Award: Yale Center for Clinical Investigation (2019)
- Dermatologist Investigator Research Fellowship: Dermatology Foundation (2017)
- Mentorship Award: Medical Dermatology Society (2017)
- AB of Dermatology, Dermatology (2017)
- Lupus Research Alliance (2022 - Present): Grant Reviewer
- International Dermatology Outcome Measures (IDEOM) (2021 - Present): Member
- National Psoriasis Foundation (2020 - Present): Member
- Rheumatological Dermatology Society (2020 - Present): Member
- Society for Immunotherapy of Cancer (SITC) (2020 - Present): Member
- American Academy of Dermatology (2018 - Present): Fellow
- Society of Investigative Dermatology (2018 - 2020): Board Member
- Society for Investigative Dermatology (2018 - 2020): Board Member
- New England Dermatological Society (NEDS) (2017 - Present): Member
- Society for Investigative Dermatology (2014 - Present): Member
- Vesely M, Kidacki M, Gaule P, Gupta S, Chan N, Han X, Yeung J, Chen L. Immune Inhibitory Molecule PD-1 Homolog (VISTA) Colocalizes with CD11b Myeloid Cells in Melanoma and Is Associated with Poor Outcomes. Journal Of Investigative Dermatology 2023, 144: 106-115.e4. PMID: 37562584, DOI: 10.1016/j.jid.2023.07.008.
- Vesely MD, Zhang T, Chen L. Resistance Mechanisms to Anti-PD Cancer Immunotherapy. Annual Review Of Immunology 2022, 40: 45-74. PMID: 35471840, DOI: 10.1146/annurev-immunol-070621-030155.
- Zheng L, Han X, Yao S, Zhu Y, Klement J, Wu S, Ji L, Zhu G, Cheng X, Tobiasova Z, Yu W, Huang B, Vesely MD, Wang J, Zhang J, Quinlan E, Chen L. The CD8α–PILRα interaction maintains CD8+ T cell quiescence. Science 2022, 376: 996-1001. PMID: 35617401, DOI: 10.1126/science.aaz8658.
- Lozano AX, Chaudhuri AA, Nene A, Bacchiocchi A, Earland N, Vesely MD, Usmani A, Turner BE, Steen CB, Luca BA, Badri T, Gulati GS, Vahid MR, Khameneh F, Harris PK, Chen DY, Dhodapkar K, Sznol M, Halaban R, Newman AM. T cell characteristics associated with toxicity to immune checkpoint blockade in patients with melanoma. Nature Medicine 2022, 28: 353-362. PMID: 35027754, PMCID: PMC8866214, DOI: 10.1038/s41591-021-01623-z.
- Han X, Vesely MD, Yang W, Sanmamed MF, Badri T, Alawa J, López-Giráldez F, Gaule P, Lee SW, Zhang JP, Nie X, Nassar A, Boto A, Flies DB, Zheng L, Kim TK, Moeckel GW, McNiff JM, Chen L. PD-1H (VISTA)–mediated suppression of autoimmunity in systemic and cutaneous lupus erythematosus. Science Translational Medicine 2019, 11 PMID: 31826980, DOI: 10.1126/scitranslmed.aax1159.
- Little AJ, Vesely MD. Cutaneous Lupus Erythematosus: Current and Future Pathogenesis-Directed Therapies. The Yale Journal Of Biology And Medicine 2020, 93: 81-95. PMID: 32226339, PMCID: PMC7087060.
- Gubin MM, Vesely MD. Cancer Immunoediting in the Era of Immuno-oncology. Clinical Cancer Research 2022, 28: 3917-3928. PMID: 35594163, PMCID: PMC9481657, DOI: 10.1158/1078-0432.ccr-21-1804.
- Vesely M, Martinez-Morilla S, Gehlhausen JR, McNiff JM, Whang PG, Rimm D, Ko CJ. Not all well-differentiated cutaneous squamous cell carcinomas are equal: Tumors with disparate biologic behavior have differences in protein expression via digital spatial profiling. Journal Of The American Academy Of Dermatology 2022, 87: 695-698. PMID: 35398219, DOI: 10.1016/j.jaad.2022.03.057.
- Park J, Park E, Damsky W, Vesely M. Pembrolizumab-induced lichenoid dermatitis treated with dupilumab. JAAD Case Reports 2023, 37: 13-15. PMID: 37332364, PMCID: PMC10275729, DOI: 10.1016/j.jdcr.2023.05.004.
- Park JJ, Little AJ, Vesely MD. Treatment of cutaneous lupus with topical ruxolitinib cream. JAAD Case Reports 2022, 28: 133-135. PMID: 36159722, PMCID: PMC9494033, DOI: 10.1016/j.jdcr.2022.08.038.
- Little A, Chen P, Vesely M, Khan R, Fiedler J, Garritano J, Islam F, McNiff J, Craft J. HIF-1 regulates pathogenic cytotoxic T cells in lupus skin disease. JCI Insight 2023, 8: e166076. PMID: 37526979, PMCID: PMC10543720, DOI: 10.1172/jci.insight.166076.
- Kidacki M, Cho C, Lopez-Giraldez F, Jaiswal A, Breidbart R, Damsky W, Vesely M, Chen L. 812 VISTA immune checkpoint is dysregulated in hidradenitis suppurativa. Journal Of Investigative Dermatology 2024, 144: s141. DOI: 10.1016/j.jid.2024.06.828.
- Vesely M, Garritano J, Damsky W, McNiff J, Chen L. 748 PD-1H/VISTA agonism as a potential therapy for cutaneous lupus. Journal Of Investigative Dermatology 2024, 144: s131. DOI: 10.1016/j.jid.2024.06.764.
- Singh K, Breidbart R, Jaiswal A, Damsky W, Choate K, Vesely M. Intravenous immunoglobulin-induced eczematous dermatitis treated with dupilumab. JAAD Case Reports 2024, 49: 102-105. PMID: 38952857, PMCID: PMC11214983, DOI: 10.1016/j.jdcr.2024.05.002.
- Zhang T, Yu W, Cheng X, Yeung J, Ahumada V, Norris P, Pearson M, Yang X, van Deursen W, Halcovich C, Nassar A, Vesely M, Zhang Y, Zhang J, Ji L, Flies D, Liu L, Langermann S, LaRochelle W, Humphrey R, Zhao D, Zhang Q, Zhang J, Gu R, Schalper K, Sanmamed M, Chen L. Up-regulated PLA2G10 in cancer impairs T cell infiltration to dampen immunity. Science Immunology 2024, 9: eadh2334. PMID: 38669316, DOI: 10.1126/sciimmunol.adh2334.
- Garritano J, Kidacki M, Cho C, Lopez-Giraldez F, Damsky W, Chen L, Vesely M. 207 Spatial proteomic and transcriptomic profiling of lichen planus reveals a unique inflammatory architecture. Journal Of Investigative Dermatology 2023, 143: s367. DOI: 10.1016/j.jid.2023.09.215.
- Noelle R, Lines J, Lewis L, Martell R, Guillaudeux T, Lee S, Mahoney K, Vesely M, Boyd-Kirkup J, Nambiar D, Scott A. Clinical and research updates on the VISTA immune checkpoint: immuno-oncology themes and highlights. Frontiers In Oncology 2023, 13: 1225081. PMID: 37795437, PMCID: PMC10547146, DOI: 10.3389/fonc.2023.1225081.
- Olamiju B, Leventhal J, Vesely M. Crusted Scabies Presenting as Erythroderma in a Patient With Iatrogenic Immunosuppression for Treatment of Granulomatosis With Polyangiitis. Cutis 2023, 111: e44-e47. PMID: 37406327, DOI: 10.12788/cutis.0794.
- Fan R, Johnston MS, Gowen MF, Damsky W, Odell I, Clune J, Vesely MD. Amelanotic melanoma in a patient with Hermansky-Pudlak syndrome. JAAD Case Reports 2022, 27: 61-63. PMID: 35990226, PMCID: PMC9388864, DOI: 10.1016/j.jdcr.2022.06.035.
- Peterson DM, Damsky WE, Vesely MD. Fever, Hypotension, and a Worsening Necrotic Wound. JAMA 2022, 327: 1496-1497. PMID: 35311923, DOI: 10.1001/jama.2022.2806.
- Peterson DM, Damsky WE, Vesely MD. Treatment of lichen sclerosus and hypertrophic scars with dupilumab. JAAD Case Reports 2022, 23: 76-78. PMID: 35445148, PMCID: PMC9014314, DOI: 10.1016/j.jdcr.2022.03.002.
- Murphy MJ, Damsky W, Vesely MD. A pruritic psoriatic plaque develops at the donor site of an autologous skin graft: Koebner phenomenon. The Lancet 2021, 398: 1836. PMID: 34774145, DOI: 10.1016/s0140-6736(21)02332-1.
- Wang A, Fogel AL, Murphy MJ, Panse G, McGeary MK, McNiff JM, Bosenberg M, Vesely MD, Cohen JM, Ko CJ, King BA, Damsky W. Cytokine RNA In Situ Hybridization Permits Individualized Molecular Phenotyping in Biopsies of Psoriasis and Atopic Dermatitis. JID Innovations 2021, 1: 100021. PMID: 34909719, PMCID: PMC8659380, DOI: 10.1016/j.xjidi.2021.100021.
- Yeung J, Yaghoobi V, Miyagishima D, Vesely MD, Zhang T, Badri T, Nassar A, Han X, Sanmamed MF, Youngblood M, Peyre M, Kalamarides M, Rimm DL, Gunel M, Chen L. Targeting the CSF1/CSF1R axis is a potential treatment strategy for malignant meningiomas. Neuro-Oncology 2021, 23: 1922-1935. PMID: 33914067, PMCID: PMC8563319, DOI: 10.1093/neuonc/noab075.
- Zhou A, Damsky W, Girardi M, Foss FM, Vesely MD. Necrotic papulonodules on the legs. JAAD Case Reports 2021, 11: 10-12. PMID: 33898676, PMCID: PMC8056172, DOI: 10.1016/j.jdcr.2021.03.012.
- A Burned-Out CD8+ T-cell Subset Expands in the Tumor Microenvironment and Curbs Cancer ImmunotherapySanmamed MF, Nie X, Desai SS, Villaroel-Espindola F, Badri T, Zhao D, Kim AW, Ji L, Zhang T, Quinlan E, Cheng X, Han X, Vesely MD, Nassar AF, Sun J, Zhang Y, Kim TK, Wang J, Melero I, Herbst RS, Schalper KA, Chen L. A Burned-Out CD8+ T-cell Subset Expands in the Tumor Microenvironment and Curbs Cancer Immunotherapy. Cancer Discovery 2021, 11: 1700-1715. PMID: 33658301, PMCID: PMC9421941, DOI: 10.1158/2159-8290.cd-20-0962.
- Peterson DM, Vesely MD. Remission of severe atopic dermatitis with dupilumab and rescue tofacitinib therapy. JAAD Case Reports 2021, 10: 4-7. PMID: 33728367, PMCID: PMC7935686, DOI: 10.1016/j.jdcr.2021.01.020.
- Yeung J, Yaghoobi V, Aung TN, Vesely MD, Zhang T, Gaule P, Gunel M, Rimm DL, Chen L. Spatially Resolved and Quantitative Analysis of the Immunological Landscape in Human Meningiomas. Journal Of Neuropathology & Experimental Neurology 2021, 80: 150-159. PMID: 33393633, DOI: 10.1093/jnen/nlaa152.
- Murphy MJ, Cohen JM, Vesely MD, Damsky W. Paradoxical eruptions to targeted therapies in dermatology: A systematic review and analysis. Journal Of The American Academy Of Dermatology 2020, 86: 1080-1091. PMID: 33307146, DOI: 10.1016/j.jaad.2020.12.010.
- Zubek AE, Vesely MD. Onychodystrophy associated with dupilumab therapy for atopic dermatitis. JAAD Case Reports 2020, 7: 20-22. PMID: 33318995, PMCID: PMC7727284, DOI: 10.1016/j.jdcr.2020.10.024.
- Vesely MD, Perkins SH. Caution in the time of rashes and COVID-19. Journal Of The American Academy Of Dermatology 2020, 83: e321-e322. PMID: 32682026, PMCID: PMC7362801, DOI: 10.1016/j.jaad.2020.07.026.
- Ramseier JY, Cowper SE, Leventhal JS, Vesely MD. A rapidly growing, exophytic nodule on the chest. JAAD Case Reports 2020, 6: 417-419. PMID: 32382633, PMCID: PMC7200183, DOI: 10.1016/j.jdcr.2020.02.038.
- Yeung JT, Vesely MD, Miyagishima DF. In silico analysis of the immunological landscape of pituitary adenomas. Journal Of Neuro-Oncology 2020, 147: 595-598. PMID: 32236778, PMCID: PMC7261241, DOI: 10.1007/s11060-020-03476-x.
- Vesely MD. Getting Under the Skin: Targeting Cutaneous Autoimmune Disease. The Yale Journal Of Biology And Medicine 2020, 93: 197-206. PMID: 32226348, PMCID: PMC7087062.
- Peterson DM, Vesely MD. Successful treatment of alopecia totalis with ruxolitinib in a preadolescent patient. JAAD Case Reports 2020, 6: 257-259. PMID: 32258291, PMCID: PMC7109366, DOI: 10.1016/j.jdcr.2020.02.007.
- Vesely MD, Olamiju BA, Leventhal JS. Tense Bullae and Pruritus. American Family Physician 2020, 101: 305-306. PMID: 32109022, PMCID: PMC7255498.
- Vesely MD, Chen L. Normalization Cancer Immunotherapy for Melanoma. Journal Of Investigative Dermatology 2020, 140: 1134-1142. PMID: 32092349, PMCID: PMC7247948, DOI: 10.1016/j.jid.2020.02.005.
- Damsky WE, Vesely MD, Lee AI, Choi J, Meyer AC, Chen M, Ahmad T, King B. Drug-induced hypersensitivity syndrome with myocardial involvement treated with tofacitinib. JAAD Case Reports 2019, 5: 1018-1026. PMID: 31763425, PMCID: PMC6864390, DOI: 10.1016/j.jdcr.2019.07.004.
- Genetic Autoinflammatory DisordersPediatric Dermatology and Dermatopathology
- Han X, Vesely MD. Chapter One Stimulating T Cells Against Cancer With Agonist Immunostimulatory Monoclonal Antibodies. International Review Of Cytology 2018, 342: 1-25. PMID: 30635089, PMCID: PMC6487201, DOI: 10.1016/bs.ircmb.2018.07.003.
- Vesely MD, Imaeda S, King BA. Tofacitinib citrate for the treatment of refractory, severe chronic actinic dermatitis. JAAD Case Reports 2016, 3: 4-6. PMID: 28050588, PMCID: PMC5192094, DOI: 10.1016/j.jdcr.2016.09.008.
- Vesely MD. A Serendipitous Retreat into Research Techniques Made Simple. Journal Of Investigative Dermatology 2016, 136: e123. PMID: 27884294, PMCID: PMC7232641, DOI: 10.1016/j.jid.2016.10.009.
- Damsky WE, Leventhal JS, Khalil D, Vesely MD, Craiglow BG, Milstone LM, Choate KA. Recurrent Coxsackievirus Infection in a Patient with Lamellar Ichthyosis. Pediatric Dermatology 2016, 33: e140-e142. PMID: 26821985, PMCID: PMC7226923, DOI: 10.1111/pde.12769.
- Gubin MM, Zhang X, Schuster H, Caron E, Ward JP, Noguchi T, Ivanova Y, Hundal J, Arthur CD, Krebber WJ, Mulder GE, Toebes M, Vesely MD, Lam SS, Korman AJ, Allison JP, Freeman GJ, Sharpe AH, Pearce EL, Schumacher TN, Aebersold R, Rammensee HG, Melief CJ, Mardis ER, Gillanders WE, Artyomov MN, Schreiber RD. Checkpoint blockade cancer immunotherapy targets tumour-specific mutant antigens. Nature 2014, 515: 577-581. PMID: 25428507, PMCID: PMC4279952, DOI: 10.1038/nature13988.
- Vesely MD, Schreiber RD. Cancer immunoediting: antigens, mechanisms, and implications to cancer immunotherapy. Annals Of The New York Academy Of Sciences 2013, 1284: 1-5. PMID: 23651186, PMCID: PMC3648872, DOI: 10.1111/nyas.12105.
- Teng MW, Vesely MD, Duret H, McLaughlin N, Towne JE, Schreiber RD, Smyth MJ. Opposing Roles for IL-23 and IL-12 in Maintaining Occult Cancer in an Equilibrium State. Cancer Research 2012, 72: 3987-3996. PMID: 22869585, PMCID: PMC4384890, DOI: 10.1158/0008-5472.can-12-1337.
- Matsushita H, Vesely MD, Koboldt DC, Rickert CG, Uppaluri R, Magrini VJ, Arthur CD, White JM, Chen YS, Shea LK, Hundal J, Wendl MC, Demeter R, Wylie T, Allison JP, Smyth MJ, Old LJ, Mardis ER, Schreiber RD. Cancer exome analysis reveals a T-cell-dependent mechanism of cancer immunoediting. Nature 2012, 482: 400-404. PMID: 22318521, PMCID: PMC3874809, DOI: 10.1038/nature10755.
- Vesely MD, Kershaw MH, Schreiber RD, Smyth MJ. Natural Innate and Adaptive Immunity to Cancer. Annual Review Of Immunology 2011, 29: 235-271. PMID: 21219185, DOI: 10.1146/annurev-immunol-031210-101324.
- Swann JB, Vesely MD, Silva A, Sharkey J, Akira S, Schreiber RD, Smyth MJ. Demonstration of inflammation-induced cancer and cancer immunoediting during primary tumorigenesis. Proceedings Of The National Academy Of Sciences Of The United States Of America 2008, 105: 652-656. PMID: 18178624, PMCID: PMC2206591, DOI: 10.1073/pnas.0708594105.
- Vesely M, Gower W, Perez-Lamboy G, Overton R, Graddy L, Vesely D. Evidence for an Atrial Natriuretic Peptide–-Like Gene in Plants. Experimental Biology And Medicine 2001, 226: 61-65. PMID: 11368240, DOI: 10.1177/153537020122600109.
- Vesely M, Vesely D. Environmental Upregulation of the Atrial Natriuretic Peptide Gene in the Living Fossil,Limulus polyphemus. Biochemical And Biophysical Research Communications 1999, 254: 751-756. PMID: 9920813, DOI: 10.1006/bbrc.1998.9990.
- Yale Dermatology BranfordYale Dermatology - Branford322 East Main Street, Ste Suite 2GBranford, CT 06405
Biography
Matthew Vesely, MD, is a dermatologist who treats psoriasis, eczema, and other autoimmune skin disorders. Dr. Vesely also sees patients with chronic skin diseases, including discoid lupus erythematosus (DLE) and hidradenitis suppurativa (HS).
“Seeing patients who have been suffering from inflammatory skin diseases for years finally get relief with the help of a targeted therapy is very rewarding,” he says.
Dr. Vesely says he enjoys working with patients and their families to find the best approach to treat a skin disorder. “I always explain that even if the first set of therapies are ineffective, we won't stop until we find the most effective treatment plan,” he says.
Dr. Vesely says he chose his specialty after learning that a large number of skin diseases caused by an overactive immune system lack FDA-approved treatments. In his research, Dr. Vesely investigates emerging new therapies that could potentially help his patients.
“Being able to research the same diseases I treat is extremely gratifying and motivating,” Dr. Vesely says.
Titles
- Assistant Professor of Dermatology
Education & Training
- ResidentYale School of Medicine (Dermatology) (2014-2017) (2017)
- InternBarnes Jewish Hospital (St. Louis) (2013-2014) (2014)
- PhDWashington University School of Medicine, St. Louis, Immunology (2013)
- MDWashington University School of Medicine (2013)
- BSCreighton University, Biology, Theology, History (2003)
Additional Information
- Dermatology Fellows Award: Melanoma Research Alliance (2019)
- Physician-Scientist Career Development Award: Dermatology Foundation (2019)
- YCCI Research Scholar Award: Yale Center for Clinical Investigation (2019)
- Dermatologist Investigator Research Fellowship: Dermatology Foundation (2017)
- Mentorship Award: Medical Dermatology Society (2017)
- AB of Dermatology, Dermatology (2017)
- Lupus Research Alliance (2022 - Present): Grant Reviewer
- International Dermatology Outcome Measures (IDEOM) (2021 - Present): Member
- National Psoriasis Foundation (2020 - Present): Member
- Rheumatological Dermatology Society (2020 - Present): Member
- Society for Immunotherapy of Cancer (SITC) (2020 - Present): Member
- American Academy of Dermatology (2018 - Present): Fellow
- Society of Investigative Dermatology (2018 - 2020): Board Member
- Society for Investigative Dermatology (2018 - 2020): Board Member
- New England Dermatological Society (NEDS) (2017 - Present): Member
- Society for Investigative Dermatology (2014 - Present): Member
- Vesely M, Kidacki M, Gaule P, Gupta S, Chan N, Han X, Yeung J, Chen L. Immune Inhibitory Molecule PD-1 Homolog (VISTA) Colocalizes with CD11b Myeloid Cells in Melanoma and Is Associated with Poor Outcomes. Journal Of Investigative Dermatology 2023, 144: 106-115.e4. PMID: 37562584, DOI: 10.1016/j.jid.2023.07.008.
- Vesely MD, Zhang T, Chen L. Resistance Mechanisms to Anti-PD Cancer Immunotherapy. Annual Review Of Immunology 2022, 40: 45-74. PMID: 35471840, DOI: 10.1146/annurev-immunol-070621-030155.
- Zheng L, Han X, Yao S, Zhu Y, Klement J, Wu S, Ji L, Zhu G, Cheng X, Tobiasova Z, Yu W, Huang B, Vesely MD, Wang J, Zhang J, Quinlan E, Chen L. The CD8α–PILRα interaction maintains CD8+ T cell quiescence. Science 2022, 376: 996-1001. PMID: 35617401, DOI: 10.1126/science.aaz8658.
- Lozano AX, Chaudhuri AA, Nene A, Bacchiocchi A, Earland N, Vesely MD, Usmani A, Turner BE, Steen CB, Luca BA, Badri T, Gulati GS, Vahid MR, Khameneh F, Harris PK, Chen DY, Dhodapkar K, Sznol M, Halaban R, Newman AM. T cell characteristics associated with toxicity to immune checkpoint blockade in patients with melanoma. Nature Medicine 2022, 28: 353-362. PMID: 35027754, PMCID: PMC8866214, DOI: 10.1038/s41591-021-01623-z.
- Han X, Vesely MD, Yang W, Sanmamed MF, Badri T, Alawa J, López-Giráldez F, Gaule P, Lee SW, Zhang JP, Nie X, Nassar A, Boto A, Flies DB, Zheng L, Kim TK, Moeckel GW, McNiff JM, Chen L. PD-1H (VISTA)–mediated suppression of autoimmunity in systemic and cutaneous lupus erythematosus. Science Translational Medicine 2019, 11 PMID: 31826980, DOI: 10.1126/scitranslmed.aax1159.
- Little AJ, Vesely MD. Cutaneous Lupus Erythematosus: Current and Future Pathogenesis-Directed Therapies. The Yale Journal Of Biology And Medicine 2020, 93: 81-95. PMID: 32226339, PMCID: PMC7087060.
- Gubin MM, Vesely MD. Cancer Immunoediting in the Era of Immuno-oncology. Clinical Cancer Research 2022, 28: 3917-3928. PMID: 35594163, PMCID: PMC9481657, DOI: 10.1158/1078-0432.ccr-21-1804.
- Vesely M, Martinez-Morilla S, Gehlhausen JR, McNiff JM, Whang PG, Rimm D, Ko CJ. Not all well-differentiated cutaneous squamous cell carcinomas are equal: Tumors with disparate biologic behavior have differences in protein expression via digital spatial profiling. Journal Of The American Academy Of Dermatology 2022, 87: 695-698. PMID: 35398219, DOI: 10.1016/j.jaad.2022.03.057.
- Park J, Park E, Damsky W, Vesely M. Pembrolizumab-induced lichenoid dermatitis treated with dupilumab. JAAD Case Reports 2023, 37: 13-15. PMID: 37332364, PMCID: PMC10275729, DOI: 10.1016/j.jdcr.2023.05.004.
- Park JJ, Little AJ, Vesely MD. Treatment of cutaneous lupus with topical ruxolitinib cream. JAAD Case Reports 2022, 28: 133-135. PMID: 36159722, PMCID: PMC9494033, DOI: 10.1016/j.jdcr.2022.08.038.
- Little A, Chen P, Vesely M, Khan R, Fiedler J, Garritano J, Islam F, McNiff J, Craft J. HIF-1 regulates pathogenic cytotoxic T cells in lupus skin disease. JCI Insight 2023, 8: e166076. PMID: 37526979, PMCID: PMC10543720, DOI: 10.1172/jci.insight.166076.
- Kidacki M, Cho C, Lopez-Giraldez F, Jaiswal A, Breidbart R, Damsky W, Vesely M, Chen L. 812 VISTA immune checkpoint is dysregulated in hidradenitis suppurativa. Journal Of Investigative Dermatology 2024, 144: s141. DOI: 10.1016/j.jid.2024.06.828.
- Vesely M, Garritano J, Damsky W, McNiff J, Chen L. 748 PD-1H/VISTA agonism as a potential therapy for cutaneous lupus. Journal Of Investigative Dermatology 2024, 144: s131. DOI: 10.1016/j.jid.2024.06.764.
- Singh K, Breidbart R, Jaiswal A, Damsky W, Choate K, Vesely M. Intravenous immunoglobulin-induced eczematous dermatitis treated with dupilumab. JAAD Case Reports 2024, 49: 102-105. PMID: 38952857, PMCID: PMC11214983, DOI: 10.1016/j.jdcr.2024.05.002.
- Zhang T, Yu W, Cheng X, Yeung J, Ahumada V, Norris P, Pearson M, Yang X, van Deursen W, Halcovich C, Nassar A, Vesely M, Zhang Y, Zhang J, Ji L, Flies D, Liu L, Langermann S, LaRochelle W, Humphrey R, Zhao D, Zhang Q, Zhang J, Gu R, Schalper K, Sanmamed M, Chen L. Up-regulated PLA2G10 in cancer impairs T cell infiltration to dampen immunity. Science Immunology 2024, 9: eadh2334. PMID: 38669316, DOI: 10.1126/sciimmunol.adh2334.
- Garritano J, Kidacki M, Cho C, Lopez-Giraldez F, Damsky W, Chen L, Vesely M. 207 Spatial proteomic and transcriptomic profiling of lichen planus reveals a unique inflammatory architecture. Journal Of Investigative Dermatology 2023, 143: s367. DOI: 10.1016/j.jid.2023.09.215.
- Noelle R, Lines J, Lewis L, Martell R, Guillaudeux T, Lee S, Mahoney K, Vesely M, Boyd-Kirkup J, Nambiar D, Scott A. Clinical and research updates on the VISTA immune checkpoint: immuno-oncology themes and highlights. Frontiers In Oncology 2023, 13: 1225081. PMID: 37795437, PMCID: PMC10547146, DOI: 10.3389/fonc.2023.1225081.
- Olamiju B, Leventhal J, Vesely M. Crusted Scabies Presenting as Erythroderma in a Patient With Iatrogenic Immunosuppression for Treatment of Granulomatosis With Polyangiitis. Cutis 2023, 111: e44-e47. PMID: 37406327, DOI: 10.12788/cutis.0794.
- Fan R, Johnston MS, Gowen MF, Damsky W, Odell I, Clune J, Vesely MD. Amelanotic melanoma in a patient with Hermansky-Pudlak syndrome. JAAD Case Reports 2022, 27: 61-63. PMID: 35990226, PMCID: PMC9388864, DOI: 10.1016/j.jdcr.2022.06.035.
- Peterson DM, Damsky WE, Vesely MD. Fever, Hypotension, and a Worsening Necrotic Wound. JAMA 2022, 327: 1496-1497. PMID: 35311923, DOI: 10.1001/jama.2022.2806.
- Peterson DM, Damsky WE, Vesely MD. Treatment of lichen sclerosus and hypertrophic scars with dupilumab. JAAD Case Reports 2022, 23: 76-78. PMID: 35445148, PMCID: PMC9014314, DOI: 10.1016/j.jdcr.2022.03.002.
- Murphy MJ, Damsky W, Vesely MD. A pruritic psoriatic plaque develops at the donor site of an autologous skin graft: Koebner phenomenon. The Lancet 2021, 398: 1836. PMID: 34774145, DOI: 10.1016/s0140-6736(21)02332-1.
- Wang A, Fogel AL, Murphy MJ, Panse G, McGeary MK, McNiff JM, Bosenberg M, Vesely MD, Cohen JM, Ko CJ, King BA, Damsky W. Cytokine RNA In Situ Hybridization Permits Individualized Molecular Phenotyping in Biopsies of Psoriasis and Atopic Dermatitis. JID Innovations 2021, 1: 100021. PMID: 34909719, PMCID: PMC8659380, DOI: 10.1016/j.xjidi.2021.100021.
- Yeung J, Yaghoobi V, Miyagishima D, Vesely MD, Zhang T, Badri T, Nassar A, Han X, Sanmamed MF, Youngblood M, Peyre M, Kalamarides M, Rimm DL, Gunel M, Chen L. Targeting the CSF1/CSF1R axis is a potential treatment strategy for malignant meningiomas. Neuro-Oncology 2021, 23: 1922-1935. PMID: 33914067, PMCID: PMC8563319, DOI: 10.1093/neuonc/noab075.
- Zhou A, Damsky W, Girardi M, Foss FM, Vesely MD. Necrotic papulonodules on the legs. JAAD Case Reports 2021, 11: 10-12. PMID: 33898676, PMCID: PMC8056172, DOI: 10.1016/j.jdcr.2021.03.012.
- A Burned-Out CD8+ T-cell Subset Expands in the Tumor Microenvironment and Curbs Cancer ImmunotherapySanmamed MF, Nie X, Desai SS, Villaroel-Espindola F, Badri T, Zhao D, Kim AW, Ji L, Zhang T, Quinlan E, Cheng X, Han X, Vesely MD, Nassar AF, Sun J, Zhang Y, Kim TK, Wang J, Melero I, Herbst RS, Schalper KA, Chen L. A Burned-Out CD8+ T-cell Subset Expands in the Tumor Microenvironment and Curbs Cancer Immunotherapy. Cancer Discovery 2021, 11: 1700-1715. PMID: 33658301, PMCID: PMC9421941, DOI: 10.1158/2159-8290.cd-20-0962.
- Peterson DM, Vesely MD. Remission of severe atopic dermatitis with dupilumab and rescue tofacitinib therapy. JAAD Case Reports 2021, 10: 4-7. PMID: 33728367, PMCID: PMC7935686, DOI: 10.1016/j.jdcr.2021.01.020.
- Yeung J, Yaghoobi V, Aung TN, Vesely MD, Zhang T, Gaule P, Gunel M, Rimm DL, Chen L. Spatially Resolved and Quantitative Analysis of the Immunological Landscape in Human Meningiomas. Journal Of Neuropathology & Experimental Neurology 2021, 80: 150-159. PMID: 33393633, DOI: 10.1093/jnen/nlaa152.
- Murphy MJ, Cohen JM, Vesely MD, Damsky W. Paradoxical eruptions to targeted therapies in dermatology: A systematic review and analysis. Journal Of The American Academy Of Dermatology 2020, 86: 1080-1091. PMID: 33307146, DOI: 10.1016/j.jaad.2020.12.010.
- Zubek AE, Vesely MD. Onychodystrophy associated with dupilumab therapy for atopic dermatitis. JAAD Case Reports 2020, 7: 20-22. PMID: 33318995, PMCID: PMC7727284, DOI: 10.1016/j.jdcr.2020.10.024.
- Vesely MD, Perkins SH. Caution in the time of rashes and COVID-19. Journal Of The American Academy Of Dermatology 2020, 83: e321-e322. PMID: 32682026, PMCID: PMC7362801, DOI: 10.1016/j.jaad.2020.07.026.
- Ramseier JY, Cowper SE, Leventhal JS, Vesely MD. A rapidly growing, exophytic nodule on the chest. JAAD Case Reports 2020, 6: 417-419. PMID: 32382633, PMCID: PMC7200183, DOI: 10.1016/j.jdcr.2020.02.038.
- Yeung JT, Vesely MD, Miyagishima DF. In silico analysis of the immunological landscape of pituitary adenomas. Journal Of Neuro-Oncology 2020, 147: 595-598. PMID: 32236778, PMCID: PMC7261241, DOI: 10.1007/s11060-020-03476-x.
- Vesely MD. Getting Under the Skin: Targeting Cutaneous Autoimmune Disease. The Yale Journal Of Biology And Medicine 2020, 93: 197-206. PMID: 32226348, PMCID: PMC7087062.
- Peterson DM, Vesely MD. Successful treatment of alopecia totalis with ruxolitinib in a preadolescent patient. JAAD Case Reports 2020, 6: 257-259. PMID: 32258291, PMCID: PMC7109366, DOI: 10.1016/j.jdcr.2020.02.007.
- Vesely MD, Olamiju BA, Leventhal JS. Tense Bullae and Pruritus. American Family Physician 2020, 101: 305-306. PMID: 32109022, PMCID: PMC7255498.
- Vesely MD, Chen L. Normalization Cancer Immunotherapy for Melanoma. Journal Of Investigative Dermatology 2020, 140: 1134-1142. PMID: 32092349, PMCID: PMC7247948, DOI: 10.1016/j.jid.2020.02.005.
- Damsky WE, Vesely MD, Lee AI, Choi J, Meyer AC, Chen M, Ahmad T, King B. Drug-induced hypersensitivity syndrome with myocardial involvement treated with tofacitinib. JAAD Case Reports 2019, 5: 1018-1026. PMID: 31763425, PMCID: PMC6864390, DOI: 10.1016/j.jdcr.2019.07.004.
- Genetic Autoinflammatory DisordersPediatric Dermatology and Dermatopathology
- Han X, Vesely MD. Chapter One Stimulating T Cells Against Cancer With Agonist Immunostimulatory Monoclonal Antibodies. International Review Of Cytology 2018, 342: 1-25. PMID: 30635089, PMCID: PMC6487201, DOI: 10.1016/bs.ircmb.2018.07.003.
- Vesely MD, Imaeda S, King BA. Tofacitinib citrate for the treatment of refractory, severe chronic actinic dermatitis. JAAD Case Reports 2016, 3: 4-6. PMID: 28050588, PMCID: PMC5192094, DOI: 10.1016/j.jdcr.2016.09.008.
- Vesely MD. A Serendipitous Retreat into Research Techniques Made Simple. Journal Of Investigative Dermatology 2016, 136: e123. PMID: 27884294, PMCID: PMC7232641, DOI: 10.1016/j.jid.2016.10.009.
- Damsky WE, Leventhal JS, Khalil D, Vesely MD, Craiglow BG, Milstone LM, Choate KA. Recurrent Coxsackievirus Infection in a Patient with Lamellar Ichthyosis. Pediatric Dermatology 2016, 33: e140-e142. PMID: 26821985, PMCID: PMC7226923, DOI: 10.1111/pde.12769.
- Gubin MM, Zhang X, Schuster H, Caron E, Ward JP, Noguchi T, Ivanova Y, Hundal J, Arthur CD, Krebber WJ, Mulder GE, Toebes M, Vesely MD, Lam SS, Korman AJ, Allison JP, Freeman GJ, Sharpe AH, Pearce EL, Schumacher TN, Aebersold R, Rammensee HG, Melief CJ, Mardis ER, Gillanders WE, Artyomov MN, Schreiber RD. Checkpoint blockade cancer immunotherapy targets tumour-specific mutant antigens. Nature 2014, 515: 577-581. PMID: 25428507, PMCID: PMC4279952, DOI: 10.1038/nature13988.
- Vesely MD, Schreiber RD. Cancer immunoediting: antigens, mechanisms, and implications to cancer immunotherapy. Annals Of The New York Academy Of Sciences 2013, 1284: 1-5. PMID: 23651186, PMCID: PMC3648872, DOI: 10.1111/nyas.12105.
- Teng MW, Vesely MD, Duret H, McLaughlin N, Towne JE, Schreiber RD, Smyth MJ. Opposing Roles for IL-23 and IL-12 in Maintaining Occult Cancer in an Equilibrium State. Cancer Research 2012, 72: 3987-3996. PMID: 22869585, PMCID: PMC4384890, DOI: 10.1158/0008-5472.can-12-1337.
- Matsushita H, Vesely MD, Koboldt DC, Rickert CG, Uppaluri R, Magrini VJ, Arthur CD, White JM, Chen YS, Shea LK, Hundal J, Wendl MC, Demeter R, Wylie T, Allison JP, Smyth MJ, Old LJ, Mardis ER, Schreiber RD. Cancer exome analysis reveals a T-cell-dependent mechanism of cancer immunoediting. Nature 2012, 482: 400-404. PMID: 22318521, PMCID: PMC3874809, DOI: 10.1038/nature10755.
- Vesely MD, Kershaw MH, Schreiber RD, Smyth MJ. Natural Innate and Adaptive Immunity to Cancer. Annual Review Of Immunology 2011, 29: 235-271. PMID: 21219185, DOI: 10.1146/annurev-immunol-031210-101324.
- Swann JB, Vesely MD, Silva A, Sharkey J, Akira S, Schreiber RD, Smyth MJ. Demonstration of inflammation-induced cancer and cancer immunoediting during primary tumorigenesis. Proceedings Of The National Academy Of Sciences Of The United States Of America 2008, 105: 652-656. PMID: 18178624, PMCID: PMC2206591, DOI: 10.1073/pnas.0708594105.
- Vesely M, Gower W, Perez-Lamboy G, Overton R, Graddy L, Vesely D. Evidence for an Atrial Natriuretic Peptide–-Like Gene in Plants. Experimental Biology And Medicine 2001, 226: 61-65. PMID: 11368240, DOI: 10.1177/153537020122600109.
- Vesely M, Vesely D. Environmental Upregulation of the Atrial Natriuretic Peptide Gene in the Living Fossil,Limulus polyphemus. Biochemical And Biophysical Research Communications 1999, 254: 751-756. PMID: 9920813, DOI: 10.1006/bbrc.1998.9990.
- Yale Dermatology BranfordYale Dermatology - Branford322 East Main Street, Ste Suite 2GBranford, CT 06405
- Yale Dermatology BranfordYale Dermatology - Branford322 East Main Street, Ste Suite 2GBranford, CT 06405