- Winchester Center for Lung DiseaseFitkin Memorial Pavilion789 Howard AvenueNew Haven, CT 06519
- Yale Thoracic Oncology ProgramSmilow Cancer Hospital at Yale New Haven35 Park Street, Ste 4th Floor Multispecialty Care CenterNew Haven, CT 06511
Lynn Tanoue, MD, MBA
Biography
Lynn Tanoue, MD, MBA, is a pulmonary critical care specialist who predominantly treats patients with lung cancer. At Yale New Haven Hospital, she consults on patients with pulmonary diseases, and works as a critical care specialist in the Intensive Care Unit.
Dr. Tanoue says her most rewarding moments are always with patients, though she is also a researcher and a leader in improving care overall for people with lung disease. She has been focusing on lung cancer for the past 15 years.
Dr. Tanoue founded the Yale Cancer Center Thoracic Oncology Program (TOP) in 2004. “As a pulmonologist, I was acutely aware that my patients newly diagnosed with lung cancer—or those we were worried had lung cancer—were having to deal with very complicated care with many different tests and physicians at a time when they were emotionally and sometimes physically challenged,” she says. Her goal in establishing TOP was to center the care around patients and give them ready and easy access to the variety of specialists necessary to deliver the best care. TOP provides streamlined, multidisciplinary care with physicians specializing in pulmonary medicine, thoracic surgery, medical oncology, radiation oncology, and palliative medicine, supported by a team of nurse coordinators and social workers.
Dr. Tanoue also founded the Yale Lung Screening and Nodule Program—the lung cancer screening program in TOP—after a large national clinical trial in 2011 showed that screening with low-dose radiation CT scans can help diagnose lung cancers early and save lives. Yale’s lung screening program follows the United States Preventative Services Task Force (USPSTF) screening guidelines, which are based on findings that there are benefits to routine screening for people ages 50 to 80 who have smoked at least 20 pack-years (the number of packs a person smokes each day multiplied by the number of years he or she has smoked), and who are smoking now or who have quit within in the past 15 years.
“That is not the entire group of people at risk, but that is the group of people for whom the USPSTF, which informs Medicare, recommends screenings be done,” Dr. Tanoue says. She also hopes further research will prompt the USPSTF to update its criteria. “For now, even with the reasonably tight population recommendations, screening is saving a lot of lives,” she says.
Dr. Tanoue says she always wanted to be a doctor. “My dad was a doctor, and I can't remember a time when I didn't want to be a doctor, too,” Dr. Tanoue says. Her interest in pulmonology may have also come from her father’s experience, as he had severe pulmonary tuberculosis when he was a surgical resident, before there were good medications available to treat it. Dr. Tanoue established the Yale New Haven Hospital Tuberculosis Outreach Program in 1996. The TB outreach program has performed tuberculosis screening in more than ten thousand English-as-a-Second-Language students enrolled at the New Haven Center for Adult Education, and provides a gateway for these newcomers to health care in the United States.
Dr. Tanoue is Vice-chair for Clinical Affairs in the Department of Internal Medicine at Yale School of Medicine and, in that role, helps administrate the largest department at the medical school. She is the founder of the Yale Medical Symphony Orchestra, which is made up of members of the medical center community, including doctors, scientists, nurses, and students of the many graduate programs of the Schools of Medicine, Nursing, and Public Health, well as physicians and staff at Yale New Haven Hospital, and members of the broader Yale and New Haven community.
All these initiatives have made a difference, but Dr. Tanoue says her most rewarding moments are still in the clinic. “As an academic physician, I have an advantage in that I can wear many different hats. But most of us who became doctors really did so because of the yearning to help people, and the main thing I still really love to do is go to clinic and talk to my patients.”
Titles
- Professor of Medicine (Pulmonary)
- Vice Chair for Clinical Affairs, Internal Medicine
- Director, Lung Cancer Screening Program
Education & Training
- MBAYale University (2019)
- FellowYale University School of Medicine (1988)
- Chief ResidentYale New Haven Hospital (1986)
- ResidentYale New Haven Hospital (1985)
- MDYale University (1982)
- BAHarvard-Radcliffe College (1978)
Additional Information
- Lifetime Achievement Award: ATS Thoracic Oncology Assembly (2022)
- Connecticut Magazine Top Docs 2017: Connecticut Magazine (2021)
- Connecticut Magazine Top Docs 2018: Connecticut Magazine (2021)
- Connecticut Magazine Top Docs 2019: Connecticut Magazine (2021)
- Connecticut Magazine Top Docs 2020: Connecticut Magazine (2021)
- Connecticut Magazine Top Docs 2021: Connecticut Magazine (2021)
- Connecticut Magazine Top Docs 2016: Connecticut Magazine (2016)
- Connecticut Magazine Top Docs 2015: Connecticut Magazine (2015)
- AB of Internal Medicine, Pulmonary Disease (1988)
- AB of Internal Medicine, Internal Medicine (1985)
- American Board of Internal Medicine (2019 - Present): Chair, Pulmonary Medicine Board, American Board of Internal Medicine
- American Thoracic Society (2019 - 2021): Chair, Thoracic Oncology Assembly, American Thoracic Society
- National Comprehensive Cancer Network (2018 - Present): Member, Committee on Lung Cancer Screening
- Yale New Haven Hospital (2016 - 2018): President, Medical Staff, Yale New Haven Hospital
- Detterbeck F, Woodard G, Bader A, Dacic S, Grant M, Park H, Tanoue L. The Proposed 9th Edition TNM Classification of Lung Cancer. CHEST Journal 2024 PMID: 38885896, DOI: 10.1016/j.chest.2024.05.026.
- Bade B, Zhao J, Li F, Tanoue L, Lazowski H, Alfano C, Silvestri G, Irwin M. Trends and predictors of Quality of Life in lung cancer survivors. Lung Cancer 2024, 191: 107793. PMID: 38640687, DOI: 10.1016/j.lungcan.2024.107793.
- Kunitomo Y, Sather P, Killam J, Pisani M, Slade M, Tanoue L. Impact of structured reporting for lung cancer screening low-dose CT scan incidental findings on physician management. CHEST Journal 2024 PMID: 38346557, DOI: 10.1016/j.chest.2024.02.002.
- Udelsman B, Detterbeck F, Tanoue L, Mase V, Boffa D, Blasberg J, Dhanasopon A, Ely S, Mazzarelli L, Bader A, Woodard G. Impact of the COVID-19 Pandemic on Lung Cancer Screening Processes in a Northeast Tertiary Health Care Network. Journal Of Computer Assisted Tomography 2023, 48: 222-225. PMID: 37832536, DOI: 10.1097/rct.0000000000001549.
- Tanoue L, Evans L. Maintaining Your Certification in Pulmonary Disease and Critical Care Medicine The New ABIM Longitudinal Knowledge Assessment. CHEST Journal 2023, 163: 1020-1022. PMID: 37164574, DOI: 10.1016/j.chest.2022.12.007.
- Woodard G, Tanoue L, Detterbeck F, Boffa D, Mase V, Blasberg J, Dhanasopon A, Gosangi B, Traube L, Bader A. PP01.12 Increasing Diagnosis of Ground Glass Nodules and Semi-Solid Lung Lesions on Chest CT Scans over the Past Decade. Journal Of Thoracic Oncology 2023, 18: e15. DOI: 10.1016/j.jtho.2022.09.038.
- Detterbeck F, Kumbasar U, Li A, Rubinowitz A, Traube L, Gosangi B, Udelsman B, Bade B, Ely S, Barreto G, Tanoue L, Marom E, Rivera M. Lung cancer with air lucency: a systematic review and clinical management guide. Journal Of Thoracic Disease 2023, 0: 0-0. PMID: 36910113, PMCID: PMC9992605, DOI: 10.21037/jtd-22-1199.
- Kunitomo Y, Bade B, Gunderson CG, Akgün KM, Brackett A, Tanoue L, Bastian LA. Evidence of Racial Disparities in the Lung Cancer Screening Process: a Systematic Review and Meta-Analysis. Journal Of General Internal Medicine 2022, 37: 3731-3738. PMID: 35838866, PMCID: PMC9585128, DOI: 10.1007/s11606-022-07613-2.
- Wood DE, Kazerooni EA, Aberle D, Berman A, Brown LM, Eapen GA, Ettinger DS, Ferguson JS, Hou L, Kadaria D, Klippenstein D, Kumar R, Lackner RP, Leard LE, Lennes IT, Leung ANC, Mazzone P, Merritt RE, Midthun DE, Onaitis M, Pipavath S, Pratt C, Puri V, Raz D, Reddy C, Reid ME, Sandler KL, Sands J, Schabath MB, Studts JL, Tanoue L, Tong BC, Travis WD, Wei B, Westover K, Yang SC, McCullough B, Hughes M. NCCN Guidelines® Insights: Lung Cancer Screening, Version 1.2022. Journal Of The National Comprehensive Cancer Network : JNCCN 2022, 20: 754-764. PMID: 35830884, DOI: 10.6004/jnccn.2022.0036.
- Hunihan L, Zhao D, Lazowski H, Li M, Qian Y, Abriola L, Surovtseva YV, Muthusamy V, Tanoue LT, Rothberg B, Schalper KA, Herbst RS, Wilson FH. RASGRF1 Fusions Activate Oncogenic RAS Signaling and Confer Sensitivity to MEK Inhibition. Clinical Cancer Research 2022, 28: 3091-3103. PMID: 35247929, PMCID: PMC9288503, DOI: 10.1158/1078-0432.ccr-21-4291.
- Tanoue LT, Sather P, Cortopassi I, Dicks D, Curtis A, Michaud G, Bader A, Gange C, Detterbeck F, Killam J. Standardizing the Reporting of Incidental, Non-Lung Cancer (Category S) Findings Identified on Lung Cancer Screening Low-Dose CT Imaging. CHEST Journal 2022, 161: 1697-1706. PMID: 35032477, DOI: 10.1016/j.chest.2021.12.662.
- Tanoue LT. Women and Lung Cancer. Clinics In Chest Medicine 2021, 42: 467-482. PMID: 34353452, DOI: 10.1016/j.ccm.2021.04.007.
- Kunitomo Y, Bade B, Gunderson CG, Akgün KM, Brackett A, Cain H, Tanoue L, Bastian LA. Racial Differences in Adherence to Lung Cancer Screening Follow-up A Systematic Review and Meta-analysis. CHEST Journal 2021, 161: 266-275. PMID: 34390706, DOI: 10.1016/j.chest.2021.07.2172.
- Kunitomo Y, Bade B, Gunderson C, Akgun K, Brackett A, Tanoue L, Cain H, Bastian L. A Systematic Review of Racial Disparities in Lung Cancer Screening Adherence. 2021, a1737-a1737. DOI: 10.1164/ajrccm-conference.2021.203.1_meetingabstracts.a1737.
- Bade B, Zhao J, Li F, Tanoue L, Silvestri G, Irwin M. Changes in Quality of Life in Lung Cancer Survivors: Trend and Predictors. 2021, a4793-a4793. DOI: 10.1164/ajrccm-conference.2021.203.1_meetingabstracts.a4793.
- Bade BC, Gan G, Li F, Lu L, Tanoue L, Silvestri GA, Irwin ML. “Randomized trial of physical activity on quality of life and lung cancer biomarkers in patients with advanced stage lung cancer: a pilot study”. BMC Cancer 2021, 21: 352. PMID: 33794808, PMCID: PMC8015735, DOI: 10.1186/s12885-021-08084-0.
- Kunitomo Y, Young G, Datta R, Korn LL, Tanoue L, Gautam S. A 62-Year-Old Woman With Lung Cancer, Ulcerating Rash, and Rapidly Progressive Hypoxemia. CHEST Journal 2020, 158: e191-e196. PMID: 33036118, PMCID: PMC7533682, DOI: 10.1016/j.chest.2020.06.020.
- Tanoue LT. Lung Cancer Staging. Clinics In Chest Medicine 2020, 41: 161-174. PMID: 32402353, DOI: 10.1016/j.ccm.2020.02.006.
- Kunitomo Y, Sather P, Killam J, Pisani M, Slade M, Tanoue L. The Impact of Structured Reporting of Incidental (Category S) Findings Identified on Lung Cancer Screening LDCTs on Management by Primary Care Providers. 2020, a6463-a6463. DOI: 10.1164/ajrccm-conference.2020.201.1_meetingabstracts.a6463.
- Mazzone PJ, Gould MK, Arenberg DA, Chen AC, Choi HK, Detterbeck FC, Farjah F, Fong KM, Iaccarino JM, Janes SM, Kanne JP, Kazerooni EA, MacMahon H, Naidich DP, Powell CA, Raoof S, Rivera MP, Tanner NT, Tanoue LK, Tremblay A, Vachani A, White CS, Wiener RS, Silvestri GA. Management of Lung Nodules and Lung Cancer Screening During the COVID-19 Pandemic CHEST Expert Panel Report. CHEST Journal 2020, 158: 406-415. PMID: 32335067, PMCID: PMC7177089, DOI: 10.1016/j.chest.2020.04.020.
- Mazzone PJ, Gould MK, Arenberg DA, Chen AC, Choi HK, Detterbeck FC, Farjah F, Fong KM, Iaccarino JM, Janes SM, Kanne JP, Kazerooni EA, MacMahon H, Naidich DP, Powell CA, Raoof S, Rivera MP, Tanner NT, Tanoue LK, Tremblay A, Vachani A, White CS, Wiener RS, Silvestri GA. Management of Lung Nodules and Lung Cancer Screening During the COVID-19 Pandemic CHEST Expert Panel Report. Journal Of The American College Of Radiology 2020, 17: 845-854. PMID: 32485147, PMCID: PMC7177099, DOI: 10.1016/j.jacr.2020.04.024.
- Mazzone PJ, Gould MK, Arenberg DA, Chen AC, Choi HK, Detterbeck FC, Farjah F, Fong KM, Iaccarino JM, Janes SM, Kanne JP, Kazerooni EA, MacMahon H, Naidich DP, Powell CA, Raoof S, Rivera MP, Tanner NT, Tanoue LK, Tremblay A, Vachani A, White CS, Wiener RS, Silvestri GA. Management of Lung Nodules and Lung Cancer Screening During the COVID-19 Pandemic: CHEST Expert Panel Report. Radiology Imaging Cancer 2020, 2: e204013. PMID: 33778716, PMCID: PMC7233408, DOI: 10.1148/rycan.2020204013.
- Bade B, Foley F, Tanoue L. Lessons for Precision Medicine from Lung Cancer. Respiratory Medicine 2020, 201-223. DOI: 10.1007/978-3-030-31507-8_14.
- Burks AC, Gould MK, Silvestri G, Yarmus LB, Sears CR, Arenberg DA, Gonzalez AV, Slatore CG, Tanner NT, Vachani A, Nana-Sinkam P, Fuster MM, Wahidi MM, Tanoue LT, Rivera MP. Safely and Effectively Evaluating Computed Tomography–detected Lung Lesions. Much Work to Be Done. Annals Of The American Thoracic Society 2019, 16: 1360-1362. PMID: 31437410, DOI: 10.1513/annalsats.201905-389ps.
- Godfrey M, Sather P, Tanoue L, Pisani M. Prevalence and 12-Month Downstream Costs of Incidental Findings in a Single-Center Lung Cancer Screening Program. 2019, a4474-a4474. DOI: 10.1164/ajrccm-conference.2019.199.1_meetingabstracts.a4474.
- Thomson CC, Riekert KA, Bates CK, Jena AB, Borok Z, McCallister JW, Schnapp LM, Lama VN, Kraft M, Davis SD, Finn P, Carson SS, Beck JM, Powell CA, Tanoue LT, Kaminski N, Dixon AE. Addressing Gender Inequality in Our Disciplines: Report from the Association of Pulmonary, Critical Care, and Sleep Division Chiefs. Annals Of The American Thoracic Society 2018, 15: 1382-1390. PMID: 30153425, DOI: 10.1513/annalsats.201804-252ar.
- Ye Q, Wu J, Lu Y, Naganawa M, Gallezot JD, Ma T, Liu Y, Tanoue L, Detterbeck F, Blasberg J, Chen MK, Casey M, Carson RE, Liu C. Improved discrimination between benign and malignant LDCT screening-detected lung nodules with dynamic over static 18F-FDG PET as a function of injected dose. Physics In Medicine And Biology 2018, 63: 175015. PMID: 30095083, PMCID: PMC6158045, DOI: 10.1088/1361-6560/aad97f.
- Rivera MP, Tanner NT, Silvestri GA, Detterbeck FC, Tammemägi MC, Young RP, Slatore CG, Caverly TJ, Boyd CM, Braithwaite D, Fathi JT, Gould MK, Iaccarino JM, Malkoski SP, Mazzone PJ, Tanoue LT, Schoenborn NL, Zulueta JJ, Wiener RS. Incorporating Coexisting Chronic Illness into Decisions about Patient Selection for Lung Cancer Screening. An Official American Thoracic Society Research Statement. American Journal Of Respiratory And Critical Care Medicine 2018, 198: e3-e13. PMID: 30004250, DOI: 10.1164/rccm.201805-0986st.
- Detterbeck F, Tanoue L. Chapter 16 Reflections on the Present and Future State of Lung Cancer Research and Management. 2018, 243-249. DOI: 10.1016/b978-0-323-48565-4.00016-3.
- Rothberg B, Das R, Jackson L, Lazowski H, Bai Y, O'Neill D, Roberts S, Rothberg J, Herbst R, Kim A, Boffa D, Rimm D, Detterbeck F, Tanoue L. P1.05-017 The Prognostic Impact of EGFR, KRAS and TP53 Somatic Mutations in Curatively Resected Early-Stage Lung Adenocarcinomas Topic: Translational Research and Biomarkers. Journal Of Thoracic Oncology 2017, 12: s623-s624. DOI: 10.1016/j.jtho.2016.11.801.
- Detterbeck FC, Boffa DJ, Kim AW, Tanoue LT. The Eighth Edition Lung Cancer Stage Classification. CHEST Journal 2016, 151: 193-203. PMID: 27780786, DOI: 10.1016/j.chest.2016.10.010.
- Erb CT, Su KW, Soulos PR, Tanoue LT, Gross CP. Surveillance Practice Patterns after Curative Intent Therapy for Stage I Non-Small-Cell Lung Cancer in the Medicare Population. Lung Cancer 2016, 99: 200-207. PMID: 27565940, PMCID: PMC5003420, DOI: 10.1016/j.lungcan.2016.07.017.
- Tanoue LT. Lung cancer screening. Current Opinion In Pulmonary Medicine 2016, 22: 327-335. PMID: 27159896, DOI: 10.1097/mcp.0000000000000287.
- Detterbeck FC, Marom EM, Arenberg DA, Franklin WA, Nicholson AG, Travis WD, Girard N, Mazzone PJ, Donington JS, Tanoue LT, Rusch VW, Asamura H, Rami-Porta R, Committee I, Goldstraw P, Rami-Porta R, Asamura H, Ball D, Beer D, Beyruti R, Bolejack V, Chansky K, Crowley J, Detterbeck F, Eberhardt W, Edwards J, Galateau-Sallé F, Giroux D, Gleeson F, Groome P, Huang J, Kennedy C, Kim J, Kim Y, Kingsbury L, Kondo H, Krasnik M, Kubota K, Lerut A, Lyons G, Marino M, Marom E, van Meerbeeck J, Mitchell A, Nakano T, Nicholson A, Nowak A, Peake M, Rice T, Rosenzweig K, Ruffini E, Rusch V, Saijo N, Van Schil P, Sculier J, Shemanski L, Stratton K, Suzuki K, Tachimori Y, Thomas C, Travis W, Tsao M, Turrisi A, Vansteenkiste J, Watanabe H, Wu Y, Boards A, Baas P, Erasmus J, Hasegawa S, Inai K, Kernstine K, Kindler H, Krug L, Nackaerts K, Pass H, Rice D, Falkson C, Filosso P, Giaccone G, Kondo K, Lucchi M, Okumura M, Blackstone E, Workgroup M, Flieder D, Godoy M, Goo J, Goodman L, Jett J, de Leyn P, Marchevsky A, MacMahon H, Naidich D, Okada M, Perlman M, Powell C, van Schil P, Warth A. The IASLC Lung Cancer Staging Project: Background Data and Proposals for the Application of TNM Staging Rules to Lung Cancer Presenting as Multiple Nodules with Ground Glass or Lepidic Features or a Pneumonic Type of Involvement in the Forthcoming Eighth Edition of the TNM Classification. Journal Of Thoracic Oncology 2016, 11: 666-680. PMID: 26940527, DOI: 10.1016/j.jtho.2015.12.113.
- Detterbeck FC, Bolejack V, Arenberg DA, Crowley J, Donington JS, Franklin WA, Girard N, Marom EM, Mazzone PJ, Nicholson AG, Rusch VW, Tanoue LT, Travis WD, Asamura H, Rami-Porta R, Committee I, Goldstraw P, Rami-Porta R, Asamura H, Ball D, Beer D, Beyruti R, Bolejack V, Chansky K, Crowley J, Detterbeck F, Eberhardt W, Edwards J, Galateau-Sallé F, Giroux D, Gleeson F, Groome P, Huang J, Kennedy C, Kim J, Kim Y, Kingsbury L, Kondo H, Krasnik M, Kubota K, Lerut A, Lyons G, Marino M, Marom E, van Meerbeeck J, Mitchell A, Nakano T, Nicholson A, Nowak A, Peake M, Rice T, Rosenzweig K, Ruffini E, Rusch V, Saijo N, Van Schil P, Sculier J, Shemanski L, Stratton K, Suzuki K, Tachimori Y, Thomas C, Travis W, Tsao M, Turrisi A, Vansteenkiste J, Watanabe H, Wu Y, Boards A, Baas P, Erasmus J, Hasegawa S, Inai K, Kernstine K, Kindler H, Krug L, Nackaerts K, Pass H, Rice D, Falkson C, Filosso P, Giaccone G, Kondo K, Lucchi M, Okumura M, Blackstone E, Workgroup M, Flieder D, Godoy M, Goo J, Goodman L, Jett J, de Leyn P, Marchevsky A, MacMahon H, Naidich D, Okada M, Perlman M, Powell C, van Schil P, Warth A, Institutions P, Cavaco F, Barrera E, Arca J, Lamelas I, Obrer A, Jorge R, Ball D, Bascom G, Orozco A, Castro M, Blum M, Chimondeguy D, Cvijanovic V, Defranchi S, de Olaiz Navarro B, Campuzano I, Vidueira I, Araujo E, García F, Fong K, Corral G, González S, Gilart J, Arangüena L, Barajas S, Girard P, Goksel T, Budiño M, Casaurrán G, Blanco J, Hernández J, Rodríguez H, Collantes J, Heras M, Elena J, Jakobsen E, Kostas S, Atance P, Ares A, Liao M, Losanovscky M, Lyons G, Magaroles R, De Esteban Júlvez L, Gorospe M, McCaughan B, Kennedy C, Íñiguez R, Sorribes L, Gozalo S, de Arriba C, Delgado M, Alarcón J, Cuesta J, Park J, Pass H, Fernández M, Rosenberg M, Ruffini E, Rusch V, de Cos Escuín J, Vinuesa A, Mitjans M, Strand T, Subotic D, Swisher S, Terra R, Thomas C, Tournoy K, Van Schil P, Velasquez M, Wu Y, Yokoi K. The IASLC Lung Cancer Staging Project: Background Data and Proposals for the Classification of Lung Cancer with Separate Tumor Nodules in the Forthcoming Eighth Edition of the TNM Classification for Lung Cancer. Journal Of Thoracic Oncology 2016, 11: 681-692. PMID: 26940530, DOI: 10.1016/j.jtho.2015.12.114.
- Detterbeck FC, Nicholson AG, Franklin WA, Marom EM, Travis WD, Girard N, Arenberg DA, Bolejack V, Donington JS, Mazzone PJ, Tanoue LT, Rusch VW, Crowley J, Asamura H, Rami-Porta R, Committee I, Goldstraw P, Rami-Porta R, Asamura H, Ball D, Beer D, Beyruti R, Bolejack V, Chansky K, Crowley J, Detterbeck F, Eberhardt W, Edwards J, Galateau-Sallé F, Giroux D, Gleeson F, Groome P, Huang J, Kennedy C, Kim J, Kim Y, Kingsbury L, Kondo H, Krasnik M, Kubota K, Lerut A, Lyons G, Marino M, Marom E, van Meerbeeck J, Mitchell A, Nakano T, Nicholson A, Nowak A, Peake M, Rice T, Rosenzweig K, Ruffini E, Rusch V, Saijo N, Van Schil P, Sculier J, Shemanski L, Stratton K, Suzuki K, Tachimori Y, Thomas C, Travis W, Tsao M, Turrisi A, Vansteenkiste J, Watanabe H, Wu Y, Boards A, Baas P, Erasmus J, Hasegawa S, Inai K, Kernstine K, Kindler H, Krug L, Nackaerts K, Pass H, Rice D, Falkson C, Filosso P, Giaccone G, Kondo K, Lucchi M, Okumura M, Blackstone E, Workgroup M, Flieder D, Godoy M, Goo J, Goodman L, Jett J, de Leyn P, Marchevsky A, MacMahon H, Naidich D, Okada M, Perlman M, Powell C, van Schil P, Warth A, Institutions P, Cavaco F, Barrera E, Arca J, Lamelas I, Obrer A, Jorge R, Ball D, Bascom G, Orozco A, Castro M, Blum M, Chimondeguy D, Cvijanovic V, Defranchi S, de Olaiz Navarro B, Campuzano I, Vidueira I, Araujo E, García F, Fong K, Corral G, González S, Gilart J, Arangüena L, Barajas S, Girard P, Goksel T, Budiño M, Casaurrán G, Blanco J, Hernández J, Rodríguez H, Collantes J, Heras M, Elena J, Jakobsen E, Kostas S, Atance P, Ares A, Liao M, Losanovscky M, Lyons G, Magaroles R, De Esteban Júlvez L, Gorospe M, McCaughan B, Kennedy C, Íñiguez R, Sorribes L, Gozalo S, de Arriba C, Delgado M, Alarcón J, Cuesta J, Park J, Pass H, Fernández M, Rosenberg M, Ruffini E, Rusch V, de Cos Escuín J, Vinuesa A, Mitjans M, Strand T, Subotic D, Swisher S, Terra R, Thomas C, Tournoy K, Van Schil P, Velasquez M, Wu Y, Yokoi K. The IASLC Lung Cancer Staging Project: Summary of Proposals for Revisions of the Classification of Lung Cancers with Multiple Pulmonary Sites of Involvement in the Forthcoming Eighth Edition of the TNM Classification. Journal Of Thoracic Oncology 2016, 11: 639-650. PMID: 26940528, DOI: 10.1016/j.jtho.2016.01.024.
- Detterbeck FC, Franklin WA, Nicholson AG, Girard N, Arenberg DA, Travis WD, Mazzone PJ, Marom EM, Donington JS, Tanoue LT, Rusch VW, Asamura H, Rami-Porta R, Committee I, Goldstraw P, Rami-Porta R, Asamura H, Ball D, Beer D, Beyruti R, Bolejack V, Chansky K, Crowley J, Detterbeck F, Eberhardt W, Edwards J, Galateau-Sallé F, Giroux D, Gleeson F, Groome P, Huang J, Kennedy C, Kim J, Kim Y, Kingsbury L, Kondo H, Krasnik M, Kubota K, Lerut A, Lyons G, Marino M, Marom E, van Meerbeeck J, Mitchell A, Nakano T, Nicholson A, Nowak A, Peake M, Rice T, Rosenzweig K, Ruffini E, Rusch V, Saijo N, Van Schil P, Sculier J, Shemanski L, Stratton K, Suzuki K, Tachimori Y, Thomas C, Travis W, Tsao M, Turrisi A, Vansteenkiste J, Watanabe H, Wu Y, Boards A, Baas P, Erasmus J, Hasegawa S, Inai K, Kernstine K, Kindler H, Krug L, Nackaerts K, Pass H, Rice D, Falkson C, Filosso P, Giaccone G, Kondo K, Lucchi M, Okumura M, Blackstone E, Workgroup M, Flieder D, Godoy M, Goo J, Goodman L, Jett J, de Leyn P, Marchevsky A, MacMahon H, Naidich D, Okada M, Perlman M, Powell C, van Schil P, Warth A. The IASLC Lung Cancer Staging Project: Background Data and Proposed Criteria to Distinguish Separate Primary Lung Cancers from Metastatic Foci in Patients with Two Lung Tumors in the Forthcoming Eighth Edition of the TNM Classification for Lung Cancer. Journal Of Thoracic Oncology 2016, 11: 651-665. PMID: 26944304, DOI: 10.1016/j.jtho.2016.01.025.
- Tanoue LT, Tanner NT, Gould MK, Silvestri GA. Reply: Lung Cancer Screening: The Balance between Harm and Benefit. American Journal Of Respiratory And Critical Care Medicine 2015, 191: 1209-1210. PMID: 25978579, DOI: 10.1164/rccm.201503-0526le.
- Cai S, Qin L, Tanoue L, Hu A, Jia X, Luo H, Chen Y, Chen P, Peng H. Effects of One-Hour Training Course and Spirometry on the Ability of Physicians to Diagnose and Treat Chronic Obstructive Pulmonary Disease. PLOS ONE 2015, 10: e0117348. PMID: 25706774, PMCID: PMC4338104, DOI: 10.1371/journal.pone.0117348.
- Tanoue LT, Tanner NT, Gould MK, Silvestri GA. Lung Cancer Screening. American Journal Of Respiratory And Critical Care Medicine 2015, 191: 19-33. PMID: 25369325, DOI: 10.1164/rccm.201410-1777ci.
- Reid AE, Tanoue L, Detterbeck F, Michaud GC, McCorkle R. The Role of the Advanced Practitioner in a Comprehensive Lung Cancer Screening and Pulmonary Nodule Program. Journal Of The Advanced Practitioner In Oncology 2014, 5: 440-446. PMID: 26328217, PMCID: PMC4530114, DOI: 10.6004/jadpro.2014.5.6.4.
- Erb C, Soulos P, Tanoue L, Gross C. Surveillance Practice Patterns After Curative Intent Therapy for Stage I Non-small Cell Lung Cancer in the Medicare Population. CHEST Journal 2014, 146: 607a. DOI: 10.1378/chest.1992085.
- Reid A, Detterbeck F, Michaud G, Guillod P, Tanoue L. Physicians' Assessment of Lung Cancer Risk and the Influence of Prediction Models on Decisions Relating to Lung Screening. CHEST Journal 2013, 144: 648a-648b. DOI: 10.1378/chest.1662734.
- Detterbeck FC, Postmus PE, Tanoue LT. The Stage Classification of Lung Cancer Diagnosis and Management of Lung Cancer, 3rd ed: American College of Chest Physicians Evidence-Based Clinical Practice Guidelines. CHEST Journal 2013, 143: e191s-e210s. PMID: 23649438, DOI: 10.1378/chest.12-2354.
- Ost DE, Yeung SC, Tanoue LT, Gould MK. Clinical and Organizational Factors in the Initial Evaluation of Patients With Lung Cancer Diagnosis and Management of Lung Cancer, 3rd ed: American College of Chest Physicians Evidence-Based Clinical Practice Guidelines. CHEST Journal 2013, 143: e121s-e141s. PMID: 23649435, PMCID: PMC4694609, DOI: 10.1378/chest.12-2352.
- Silvestri GA, Gonzalez AV, Jantz MA, Margolis ML, Gould MK, Tanoue LT, Harris LJ, Detterbeck FC. Methods for Staging Non-small Cell Lung Cancer Diagnosis and Management of Lung Cancer, 3rd ed: American College of Chest Physicians Evidence-Based Clinical Practice Guidelines. CHEST Journal 2013, 143: e211s-e250s. PMID: 23649440, DOI: 10.1378/chest.12-2355.
- Detterbeck F, Tanoue L, Reid A. National comprehensive cancer network. Journal Of The National Comprehensive Cancer Network 2013, 11: 365-6. PMID: 23584338, DOI: 10.6004/jnccn.2013.0050.
- Vest MT, Herrin J, Soulos PR, Decker RH, Tanoue L, Michaud G, Kim AW, Detterbeck F, Morgensztern D, Gross CP. Use of New Treatment Modalities for Non-small Cell Lung Cancer Care in the Medicare Population. CHEST Journal 2013, 143: 429-435. PMID: 23187634, PMCID: PMC3566996, DOI: 10.1378/chest.12-1149.
- Cai S, Liu F, Hu A, Chen P, Tanoue L. Effect Of Short-Term Education And Spirometry On The Diagnosis Of Chronic Obstructive Pulmonary Disease In 2nd Level Hospitals In Hunan, China. 2012, a3711-a3711. DOI: 10.1164/ajrccm-conference.2012.185.1_meetingabstracts.a3711.
- Vest MT, Tanoue L, Soulos PR, Kim AW, Detterbeck F, Morgensztern D, Gross CP. Thoroughness of Mediastinal Staging in Stage IIIA Non-small Cell Lung Cancer. Journal Of Thoracic Oncology 2012, 7: 188-195. PMID: 22134069, PMCID: PMC3253367, DOI: 10.1097/jto.0b013e318236ecbb.
- Tanoue L, Matthay R. Preface. Clinics In Chest Medicine 2011, 32: xiii-xiv. DOI: 10.1016/j.ccm.2011.08.016.
- Dela Cruz CS, Tanoue LT, Matthay RA. Lung Cancer: Epidemiology, Etiology, and Prevention. Clinics In Chest Medicine 2011, 32: 605-644. PMID: 22054876, PMCID: PMC3864624, DOI: 10.1016/j.ccm.2011.09.001.
- Gettinger S, Tanoue L. Lung Cancer in Older Patients. Respiratory Medicine 2011, 89-109. DOI: 10.1007/978-1-60761-727-3_5.
- Anagnostou VK, Dimou AT, Botsis T, Killiam EJ, Gustavson MD, Homer RJ, Boffa D, Zolota V, Dougenis D, Tanoue L, Gettinger SN, Detterbeck FC, Syrigos KN, Bepler G, Rimm DL. Molecular classification of nonsmall cell lung cancer using a 4‐protein quantitative assay. Cancer 2011, 118: 1607-1618. PMID: 22009766, DOI: 10.1002/cncr.26450.
- Vest M, Tanoue L, Soulos P, Kim A, Gross C. Adoption Of Invasive Clinical Staging Techniques In Stage IIIA Non-Small Cell Lung Cancer Lags Adoption Of Positron Emission Tomography. 2011, a5380-a5380. DOI: 10.1164/ajrccm-conference.2011.183.1_meetingabstracts.a5380.
- Lung CancerTanoue, LT. Lung Cancer. In Yearbook of Pulmonary Medicine 2011. JA Barker, Ed. Elsevier Mosby, Philadelphia. 2011, pp 61-106.
- Lung Cancer in Older Patients.Gettinger S. and Tanoue, LT. Lung Cancer in Older Patients. In Aging and Lung Diseases, M. Pisani Ed, Springer, New York, 2011, pp 89-110.
- Boffa DJ, Detterbeck FC, Smith EJ, Rami-Porta R, Crowley J, Zelterman D, Tanoue L, Kim AW, Goldstraw P. Should the 7th Edition of the Lung Cancer Stage Classification System Change Treatment Algorithms in Non-small Cell Lung Cancer? Journal Of Thoracic Oncology 2010, 5: 1779-1783. PMID: 20975377, DOI: 10.1097/jto.0b013e3181ee80c7.
- Anagnostou V, Botsis T, Killiam E, Zolota V, Dougenis D, Tanoue L, Detterbeck F, Syrigos K, Bepler G, Rimm D. Molecular classification of non-small cell lung cancer using a four protein quantitative assay. Journal Of Clinical Oncology 2010, 28: 10528-10528. DOI: 10.1200/jco.2010.28.15_suppl.10528.
- Anagnostou VK, Lowery FJ, Zolota V, Tzelepi V, Gopinath A, Liceaga C, Panagopoulos N, Frangia K, Tanoue L, Boffa D, Gettinger S, Detterbeck F, Homer RJ, Dougenis D, Rimm DL, Syrigos KN. High expression of BCL-2 predicts favorable outcome in non-small cell lung cancer patients with non squamous histology. BMC Cancer 2010, 10: 186. PMID: 20459695, PMCID: PMC2875218, DOI: 10.1186/1471-2407-10-186.
- Detterbeck FC, Boffa DJ, Tanoue LT, Wilson LD. Details and Difficulties Regarding the New Lung Cancer Staging System. CHEST Journal 2010, 137: 1172-1180. PMID: 20442118, DOI: 10.1378/chest.09-2626.
- Anagnostou V, Kolokytha P, Dimou A, Killiam E, Zolota V, Dougenis D, Frangia K, Tanoue L, Detterbeck F, Syrigos K, Bepler G, Rimm D. Abstract 4643: A novel 3-biomarker quantitative protein assay predicts survival in stage I lung squamous cell carcinomas. Cancer Research 2010, 70: 4643-4643. DOI: 10.1158/1538-7445.am10-4643.
- Lung CancerTanoue. LT. Lung Cancer. In Breathing in America: Diseases, Progress, and Hope. Ed. De Schraufnagel. American Thoracic Society 2010, pp. 109-120.
- DETTERBECK FC, TANOUE LT, BOFFA DJ, 杨 永, 李 志. Anatomy, Biology and Concepts, Pertaining to Lung Cancer Stage Classifcation. Chinese Journal Of Lung Cancer 2010, 13: 1-8. PMID: 20672696, PMCID: PMC6136057, DOI: 10.3779/j.issn.1009-3419.2010.01.01.
- Detterbeck FC, Boffa DJ, Tanoue LT. The New Lung Cancer Staging System. CHEST Journal 2009, 136: 260-271. PMID: 19584208, DOI: 10.1378/chest.08-0978.
- Anagnostou VK, Bepler G, Syrigos KN, Tanoue L, Gettinger S, Homer RJ, Boffa D, Detterbeck F, Rimm DL. High Expression of Mammalian Target of Rapamycin Is Associated with Better Outcome for Patients with Early Stage Lung Adenocarcinoma. Clinical Cancer Research 2009, 15: 4157-4164. PMID: 19509151, DOI: 10.1158/1078-0432.ccr-09-0099.
- Anagnostou V, Lowery F, Syrigos K, Frangia K, Zolota V, Panagopoulos N, Dougenis D, Tanoue L, Detterbeck F, Homer R, Rimm D. Association of expression of bcl-2 with outcome in non-small cell lung cancer. Journal Of Clinical Oncology 2009, 27: e22039-e22039. DOI: 10.1200/jco.2009.27.15_suppl.e22039.
- Detterbeck FC, Tanoue LT, Boffa DJ. Anatomy, Biology and Concepts, Pertaining to Lung Cancer Stage Classification. Journal Of Thoracic Oncology 2009, 4: 437-443. PMID: 19333070, DOI: 10.1097/jto.0b013e31819852ed.
- Tanoue LT, Detterbeck FC. New TNM classification for non-small-cell lung cancer. Expert Review Of Anticancer Therapy 2009, 9: 413-423. PMID: 19374596, DOI: 10.1586/era.09.11.
- Pulmonary Problems in Lung Cancer SurvivorsMiller K and Tanoue LT. Pulmonary Problems in Lung Cancer Survivors. In Medical and Psychosocial Care of the Cancer Survivor. KD Miller, Ed. Jones and Bartlett Publishers, Sudbury, MA. 2009, pp 299-312.
- Lung Cancer: Epidemiology and Carcinogenesis.Dela Cruz C, Tanoue LT, and Matthay RT. Lung Cancer: Epidemiology and Carcinogenesis. In General Thoracic Surgery, Seventh Edition; Shields TW, Locicero J III, Reed CD, and Feins RH, and Rusch VW, Eds. Lippincott, Williams & Wilkins, Philadelphia. 2009, pp 1281-1298.
- Silvestri G, Tanoue L. Lung Cancer: Evolving Concepts. Seminars In Respiratory And Critical Care Medicine 2008, 29: 221-222. PMID: 18506659, DOI: 10.1055/s-2008-1076741.
- Tanoue LT. Staging of Non-Small Cell Lung Cancer. Seminars In Respiratory And Critical Care Medicine 2008, 29: 248-260. PMID: 18506663, DOI: 10.1055/s-2008-1076745.
- Tanoue L. Introduction. Yearbook Of Pulmonary Disease 2008, 2008: 99-101. DOI: 10.1016/s8756-3452(08)70592-9.
- Tanoue LT, Gettinger S. Treatment of Lung Cancer in Older Patients. Clinics In Chest Medicine 2007, 28: 735-749. PMID: 17967291, DOI: 10.1016/j.ccm.2007.08.003.
- Kapoor JR, Monteiro B, Tanoue L, Siegel MD. Massive Intravascular Hemolysis and a Rapidly Fatal Outcome. CHEST Journal 2007, 132: 2016-2019. PMID: 18079238, DOI: 10.1378/chest.07-0853.
- Silvestri GA, Gould MK, Margolis ML, Tanoue LT, McCrory D, Toloza E, Detterbeck F. Noninvasive Staging of Non-small Cell Lung Cancer ACCP Evidenced-Based Clinical Practice Guidelines (2nd Edition). CHEST Journal 2007, 132: 178s-201s. PMID: 17873168, DOI: 10.1378/chest.07-1360.
- Tanoue L. Introduction. Yearbook Of Pulmonary Disease 2007, 2007: 99-101. DOI: 10.1016/s8756-3452(08)70344-x.
- Decker RH, Tanoue LT, Colasanto JM, Detterbeck FC, Wilson LD. Evaluation and definitive management of medically inoperable early stage non-small-cell lung cancer. Part 2: newer treatment modalities. Oncology 2006, 20: 899-905; discussion 905-8, 913. PMID: 16922260.
- Decker RH, Tanoue LT, Colasanto JM, Detterbeck FC, Wilson LD. Evaluation and definitive management of medically inoperable early-stage non-small-cell lung cancer. Part 1: Assessment and conventional radiotherapy. Oncology 2006, 20: 727-36. PMID: 16841796.
- Friedman LN, Nash ER, Bryant J, Henry S, Shi J, D'Amato J, Khaled GH, Russi MB, O'Connor PG, Edberg SC, Pisani MA, Cain HC, Tanoue L, Weissman DN. High Rate of Negative Results of Tuberculin and QuantiFERON Tests Among Individuals With a History of Positive Skin Test Results. Infection Control And Hospital Epidemiology 2006, 27: 436-441. PMID: 16671022, DOI: 10.1086/503690.
- Noble PW, Tanoue L, Homer R. Case Study Review. CHEST Journal 2005, 128: 540s-546s. PMID: 16304245, DOI: 10.1378/chest.128.5_suppl_1.540s.
- Cabot R, Harris N, McNeely W, Shepard J, Ebeling S, Ellender S, Peters C, Tanoue L, Mark E. Case 1-2003 — A 43-Year-Old Man with Fever and Night Sweats. New England Journal Of Medicine 2003, 348: 151-161. PMID: 12519926, DOI: 10.1056/nejmcpc020026.
- Silvestri GA, Tanoue LT, Margolis ML, Barker J, Detterbeck F. The Noninvasive Staging of Non-small Cell Lung Cancer* The Guidelines. CHEST Journal 2003, 123: 147s-156s. PMID: 12527574, DOI: 10.1378/chest.123.1_suppl.147s.
- Tanoue LT. Pulmonary Hypertension in the Collagen Vascular Diseases. Seminars In Respiratory And Critical Care Medicine 2003, 24: 287-296. PMID: 16088549, DOI: 10.1055/s-2003-41089.
- Tanoue LT, Ponn RB. Therapy for stage I and stage II non-small cell lung cancer. Clinics In Chest Medicine 2002, 23: 173-190. PMID: 11901910, DOI: 10.1016/s0272-5231(03)00067-4.
- Tanoue LT. CIGARETTE SMOKING AND WOMEN'S RESPIRATORY HEALTH. Clinics In Chest Medicine 2000, 21: 47-65. PMID: 10763089, DOI: 10.1016/s0272-5231(05)70007-1.
- Tanoue L. Preoperative Evaluation of the High-Risk Surgical Patient for Lung Cancer Resection. Seminars In Respiratory And Critical Care Medicine 2000, Volume 21: 421-432. PMID: 16088753, DOI: 10.1055/s-2000-9404.
- Salloum E, Tanoue L, Wackers F, Zelterman D, Hu G, Cooper D. Assessment of Cardiac and Pulmonary Function in Adult Patients with Hodgkin's Disease Treated with ABVD or MOPP/ABVD Plus Adjuvant Low-Dose Mediastinal Irradiation. Cancer Investigation 1999, 17: 171-180. PMID: 10099655, DOI: 10.3109/07357909909021418.
- Tanoue L. PULMONARY MANIFESTATIONS OF RHEUMATOID ARTHRITIS. Clinics In Chest Medicine 1998, 19: 667-685. PMID: 9917959, DOI: 10.1016/s0272-5231(05)70109-x.
- Quin JA, Letsou GV, Tanoue LT, Matthay RA, Higgins RS, Baldwin JC. Use of neodymium yttrium aluminum garnet laser in long-term palliation of airway obstruction. Connecticut Medicine 1995, 59: 407-12. PMID: 7545564.
- Redlich C, Van Bennekum A, Wirth J, Blaner W, Carter D, Tanoue L, Holm C, Cullen M. Vitamin A Chemoprevention of Lung Cancer. Advances In Experimental Medicine And Biology 1995, 375: 17-29. PMID: 7645426, DOI: 10.1007/978-1-4899-0949-7_2.
- Tanoue L. Lung transplantation. Lung 1992, 170: 187-200. PMID: 1522739, DOI: 10.1007/bf00174116.
- Tanoue L. Pulmonary involvement in collagen vascular disease. Journal Of Thoracic Imaging 1992, 7: 62. PMID: 1578527, DOI: 10.1097/00005382-199203000-00008.
- Tanoue LT, Aronson PS, Bia MJ. The effect of diuretics on extrarenal potassium tolerance. The Yale Journal Of Biology And Medicine 1982, 55: 421-8. PMID: 7183021, PMCID: PMC2596565.
- Pulmonary Toxicity Associated With Chemotherapeutic Agents.Tanoue LT and McArdle J. Pulmonary Toxicity Associated With Chemotherapeutic Agents. In Fishman’s Textbook of Pulmonary Disorders and Diseases, 3rd Edition, A.P.Fishman, Ed., McGraw Hill, Inc., New York, pp 1067-1102.
- Lung Cancer: Clinical Evaluation and StagingTanoue, LT. “Lung Cancer: Clinical Evaluation and Staging”, in Comprehensive Respiratory Medicine, Ed. SG Spiro SG and G Silvestri, Mosby, London, in press.
- Winchester Center for Lung DiseaseFitkin Memorial Pavilion789 Howard AvenueNew Haven, CT 06519
- Yale Thoracic Oncology ProgramSmilow Cancer Hospital at Yale New Haven35 Park Street, Ste 4th Floor Multispecialty Care CenterNew Haven, CT 06511
Biography
Lynn Tanoue, MD, MBA, is a pulmonary critical care specialist who predominantly treats patients with lung cancer. At Yale New Haven Hospital, she consults on patients with pulmonary diseases, and works as a critical care specialist in the Intensive Care Unit.
Dr. Tanoue says her most rewarding moments are always with patients, though she is also a researcher and a leader in improving care overall for people with lung disease. She has been focusing on lung cancer for the past 15 years.
Dr. Tanoue founded the Yale Cancer Center Thoracic Oncology Program (TOP) in 2004. “As a pulmonologist, I was acutely aware that my patients newly diagnosed with lung cancer—or those we were worried had lung cancer—were having to deal with very complicated care with many different tests and physicians at a time when they were emotionally and sometimes physically challenged,” she says. Her goal in establishing TOP was to center the care around patients and give them ready and easy access to the variety of specialists necessary to deliver the best care. TOP provides streamlined, multidisciplinary care with physicians specializing in pulmonary medicine, thoracic surgery, medical oncology, radiation oncology, and palliative medicine, supported by a team of nurse coordinators and social workers.
Dr. Tanoue also founded the Yale Lung Screening and Nodule Program—the lung cancer screening program in TOP—after a large national clinical trial in 2011 showed that screening with low-dose radiation CT scans can help diagnose lung cancers early and save lives. Yale’s lung screening program follows the United States Preventative Services Task Force (USPSTF) screening guidelines, which are based on findings that there are benefits to routine screening for people ages 50 to 80 who have smoked at least 20 pack-years (the number of packs a person smokes each day multiplied by the number of years he or she has smoked), and who are smoking now or who have quit within in the past 15 years.
“That is not the entire group of people at risk, but that is the group of people for whom the USPSTF, which informs Medicare, recommends screenings be done,” Dr. Tanoue says. She also hopes further research will prompt the USPSTF to update its criteria. “For now, even with the reasonably tight population recommendations, screening is saving a lot of lives,” she says.
Dr. Tanoue says she always wanted to be a doctor. “My dad was a doctor, and I can't remember a time when I didn't want to be a doctor, too,” Dr. Tanoue says. Her interest in pulmonology may have also come from her father’s experience, as he had severe pulmonary tuberculosis when he was a surgical resident, before there were good medications available to treat it. Dr. Tanoue established the Yale New Haven Hospital Tuberculosis Outreach Program in 1996. The TB outreach program has performed tuberculosis screening in more than ten thousand English-as-a-Second-Language students enrolled at the New Haven Center for Adult Education, and provides a gateway for these newcomers to health care in the United States.
Dr. Tanoue is Vice-chair for Clinical Affairs in the Department of Internal Medicine at Yale School of Medicine and, in that role, helps administrate the largest department at the medical school. She is the founder of the Yale Medical Symphony Orchestra, which is made up of members of the medical center community, including doctors, scientists, nurses, and students of the many graduate programs of the Schools of Medicine, Nursing, and Public Health, well as physicians and staff at Yale New Haven Hospital, and members of the broader Yale and New Haven community.
All these initiatives have made a difference, but Dr. Tanoue says her most rewarding moments are still in the clinic. “As an academic physician, I have an advantage in that I can wear many different hats. But most of us who became doctors really did so because of the yearning to help people, and the main thing I still really love to do is go to clinic and talk to my patients.”
Titles
- Professor of Medicine (Pulmonary)
- Vice Chair for Clinical Affairs, Internal Medicine
- Director, Lung Cancer Screening Program
Education & Training
- MBAYale University (2019)
- FellowYale University School of Medicine (1988)
- Chief ResidentYale New Haven Hospital (1986)
- ResidentYale New Haven Hospital (1985)
- MDYale University (1982)
- BAHarvard-Radcliffe College (1978)
Additional Information
- Lifetime Achievement Award: ATS Thoracic Oncology Assembly (2022)
- Connecticut Magazine Top Docs 2017: Connecticut Magazine (2021)
- Connecticut Magazine Top Docs 2018: Connecticut Magazine (2021)
- Connecticut Magazine Top Docs 2019: Connecticut Magazine (2021)
- Connecticut Magazine Top Docs 2020: Connecticut Magazine (2021)
- Connecticut Magazine Top Docs 2021: Connecticut Magazine (2021)
- Connecticut Magazine Top Docs 2016: Connecticut Magazine (2016)
- Connecticut Magazine Top Docs 2015: Connecticut Magazine (2015)
- AB of Internal Medicine, Pulmonary Disease (1988)
- AB of Internal Medicine, Internal Medicine (1985)
- American Board of Internal Medicine (2019 - Present): Chair, Pulmonary Medicine Board, American Board of Internal Medicine
- American Thoracic Society (2019 - 2021): Chair, Thoracic Oncology Assembly, American Thoracic Society
- National Comprehensive Cancer Network (2018 - Present): Member, Committee on Lung Cancer Screening
- Yale New Haven Hospital (2016 - 2018): President, Medical Staff, Yale New Haven Hospital
- Detterbeck F, Woodard G, Bader A, Dacic S, Grant M, Park H, Tanoue L. The Proposed 9th Edition TNM Classification of Lung Cancer. CHEST Journal 2024 PMID: 38885896, DOI: 10.1016/j.chest.2024.05.026.
- Bade B, Zhao J, Li F, Tanoue L, Lazowski H, Alfano C, Silvestri G, Irwin M. Trends and predictors of Quality of Life in lung cancer survivors. Lung Cancer 2024, 191: 107793. PMID: 38640687, DOI: 10.1016/j.lungcan.2024.107793.
- Kunitomo Y, Sather P, Killam J, Pisani M, Slade M, Tanoue L. Impact of structured reporting for lung cancer screening low-dose CT scan incidental findings on physician management. CHEST Journal 2024 PMID: 38346557, DOI: 10.1016/j.chest.2024.02.002.
- Udelsman B, Detterbeck F, Tanoue L, Mase V, Boffa D, Blasberg J, Dhanasopon A, Ely S, Mazzarelli L, Bader A, Woodard G. Impact of the COVID-19 Pandemic on Lung Cancer Screening Processes in a Northeast Tertiary Health Care Network. Journal Of Computer Assisted Tomography 2023, 48: 222-225. PMID: 37832536, DOI: 10.1097/rct.0000000000001549.
- Tanoue L, Evans L. Maintaining Your Certification in Pulmonary Disease and Critical Care Medicine The New ABIM Longitudinal Knowledge Assessment. CHEST Journal 2023, 163: 1020-1022. PMID: 37164574, DOI: 10.1016/j.chest.2022.12.007.
- Woodard G, Tanoue L, Detterbeck F, Boffa D, Mase V, Blasberg J, Dhanasopon A, Gosangi B, Traube L, Bader A. PP01.12 Increasing Diagnosis of Ground Glass Nodules and Semi-Solid Lung Lesions on Chest CT Scans over the Past Decade. Journal Of Thoracic Oncology 2023, 18: e15. DOI: 10.1016/j.jtho.2022.09.038.
- Detterbeck F, Kumbasar U, Li A, Rubinowitz A, Traube L, Gosangi B, Udelsman B, Bade B, Ely S, Barreto G, Tanoue L, Marom E, Rivera M. Lung cancer with air lucency: a systematic review and clinical management guide. Journal Of Thoracic Disease 2023, 0: 0-0. PMID: 36910113, PMCID: PMC9992605, DOI: 10.21037/jtd-22-1199.
- Kunitomo Y, Bade B, Gunderson CG, Akgün KM, Brackett A, Tanoue L, Bastian LA. Evidence of Racial Disparities in the Lung Cancer Screening Process: a Systematic Review and Meta-Analysis. Journal Of General Internal Medicine 2022, 37: 3731-3738. PMID: 35838866, PMCID: PMC9585128, DOI: 10.1007/s11606-022-07613-2.
- Wood DE, Kazerooni EA, Aberle D, Berman A, Brown LM, Eapen GA, Ettinger DS, Ferguson JS, Hou L, Kadaria D, Klippenstein D, Kumar R, Lackner RP, Leard LE, Lennes IT, Leung ANC, Mazzone P, Merritt RE, Midthun DE, Onaitis M, Pipavath S, Pratt C, Puri V, Raz D, Reddy C, Reid ME, Sandler KL, Sands J, Schabath MB, Studts JL, Tanoue L, Tong BC, Travis WD, Wei B, Westover K, Yang SC, McCullough B, Hughes M. NCCN Guidelines® Insights: Lung Cancer Screening, Version 1.2022. Journal Of The National Comprehensive Cancer Network : JNCCN 2022, 20: 754-764. PMID: 35830884, DOI: 10.6004/jnccn.2022.0036.
- Hunihan L, Zhao D, Lazowski H, Li M, Qian Y, Abriola L, Surovtseva YV, Muthusamy V, Tanoue LT, Rothberg B, Schalper KA, Herbst RS, Wilson FH. RASGRF1 Fusions Activate Oncogenic RAS Signaling and Confer Sensitivity to MEK Inhibition. Clinical Cancer Research 2022, 28: 3091-3103. PMID: 35247929, PMCID: PMC9288503, DOI: 10.1158/1078-0432.ccr-21-4291.
- Tanoue LT, Sather P, Cortopassi I, Dicks D, Curtis A, Michaud G, Bader A, Gange C, Detterbeck F, Killam J. Standardizing the Reporting of Incidental, Non-Lung Cancer (Category S) Findings Identified on Lung Cancer Screening Low-Dose CT Imaging. CHEST Journal 2022, 161: 1697-1706. PMID: 35032477, DOI: 10.1016/j.chest.2021.12.662.
- Tanoue LT. Women and Lung Cancer. Clinics In Chest Medicine 2021, 42: 467-482. PMID: 34353452, DOI: 10.1016/j.ccm.2021.04.007.
- Kunitomo Y, Bade B, Gunderson CG, Akgün KM, Brackett A, Cain H, Tanoue L, Bastian LA. Racial Differences in Adherence to Lung Cancer Screening Follow-up A Systematic Review and Meta-analysis. CHEST Journal 2021, 161: 266-275. PMID: 34390706, DOI: 10.1016/j.chest.2021.07.2172.
- Kunitomo Y, Bade B, Gunderson C, Akgun K, Brackett A, Tanoue L, Cain H, Bastian L. A Systematic Review of Racial Disparities in Lung Cancer Screening Adherence. 2021, a1737-a1737. DOI: 10.1164/ajrccm-conference.2021.203.1_meetingabstracts.a1737.
- Bade B, Zhao J, Li F, Tanoue L, Silvestri G, Irwin M. Changes in Quality of Life in Lung Cancer Survivors: Trend and Predictors. 2021, a4793-a4793. DOI: 10.1164/ajrccm-conference.2021.203.1_meetingabstracts.a4793.
- Bade BC, Gan G, Li F, Lu L, Tanoue L, Silvestri GA, Irwin ML. “Randomized trial of physical activity on quality of life and lung cancer biomarkers in patients with advanced stage lung cancer: a pilot study”. BMC Cancer 2021, 21: 352. PMID: 33794808, PMCID: PMC8015735, DOI: 10.1186/s12885-021-08084-0.
- Kunitomo Y, Young G, Datta R, Korn LL, Tanoue L, Gautam S. A 62-Year-Old Woman With Lung Cancer, Ulcerating Rash, and Rapidly Progressive Hypoxemia. CHEST Journal 2020, 158: e191-e196. PMID: 33036118, PMCID: PMC7533682, DOI: 10.1016/j.chest.2020.06.020.
- Tanoue LT. Lung Cancer Staging. Clinics In Chest Medicine 2020, 41: 161-174. PMID: 32402353, DOI: 10.1016/j.ccm.2020.02.006.
- Kunitomo Y, Sather P, Killam J, Pisani M, Slade M, Tanoue L. The Impact of Structured Reporting of Incidental (Category S) Findings Identified on Lung Cancer Screening LDCTs on Management by Primary Care Providers. 2020, a6463-a6463. DOI: 10.1164/ajrccm-conference.2020.201.1_meetingabstracts.a6463.
- Mazzone PJ, Gould MK, Arenberg DA, Chen AC, Choi HK, Detterbeck FC, Farjah F, Fong KM, Iaccarino JM, Janes SM, Kanne JP, Kazerooni EA, MacMahon H, Naidich DP, Powell CA, Raoof S, Rivera MP, Tanner NT, Tanoue LK, Tremblay A, Vachani A, White CS, Wiener RS, Silvestri GA. Management of Lung Nodules and Lung Cancer Screening During the COVID-19 Pandemic CHEST Expert Panel Report. CHEST Journal 2020, 158: 406-415. PMID: 32335067, PMCID: PMC7177089, DOI: 10.1016/j.chest.2020.04.020.
- Mazzone PJ, Gould MK, Arenberg DA, Chen AC, Choi HK, Detterbeck FC, Farjah F, Fong KM, Iaccarino JM, Janes SM, Kanne JP, Kazerooni EA, MacMahon H, Naidich DP, Powell CA, Raoof S, Rivera MP, Tanner NT, Tanoue LK, Tremblay A, Vachani A, White CS, Wiener RS, Silvestri GA. Management of Lung Nodules and Lung Cancer Screening During the COVID-19 Pandemic CHEST Expert Panel Report. Journal Of The American College Of Radiology 2020, 17: 845-854. PMID: 32485147, PMCID: PMC7177099, DOI: 10.1016/j.jacr.2020.04.024.
- Mazzone PJ, Gould MK, Arenberg DA, Chen AC, Choi HK, Detterbeck FC, Farjah F, Fong KM, Iaccarino JM, Janes SM, Kanne JP, Kazerooni EA, MacMahon H, Naidich DP, Powell CA, Raoof S, Rivera MP, Tanner NT, Tanoue LK, Tremblay A, Vachani A, White CS, Wiener RS, Silvestri GA. Management of Lung Nodules and Lung Cancer Screening During the COVID-19 Pandemic: CHEST Expert Panel Report. Radiology Imaging Cancer 2020, 2: e204013. PMID: 33778716, PMCID: PMC7233408, DOI: 10.1148/rycan.2020204013.
- Bade B, Foley F, Tanoue L. Lessons for Precision Medicine from Lung Cancer. Respiratory Medicine 2020, 201-223. DOI: 10.1007/978-3-030-31507-8_14.
- Burks AC, Gould MK, Silvestri G, Yarmus LB, Sears CR, Arenberg DA, Gonzalez AV, Slatore CG, Tanner NT, Vachani A, Nana-Sinkam P, Fuster MM, Wahidi MM, Tanoue LT, Rivera MP. Safely and Effectively Evaluating Computed Tomography–detected Lung Lesions. Much Work to Be Done. Annals Of The American Thoracic Society 2019, 16: 1360-1362. PMID: 31437410, DOI: 10.1513/annalsats.201905-389ps.
- Godfrey M, Sather P, Tanoue L, Pisani M. Prevalence and 12-Month Downstream Costs of Incidental Findings in a Single-Center Lung Cancer Screening Program. 2019, a4474-a4474. DOI: 10.1164/ajrccm-conference.2019.199.1_meetingabstracts.a4474.
- Thomson CC, Riekert KA, Bates CK, Jena AB, Borok Z, McCallister JW, Schnapp LM, Lama VN, Kraft M, Davis SD, Finn P, Carson SS, Beck JM, Powell CA, Tanoue LT, Kaminski N, Dixon AE. Addressing Gender Inequality in Our Disciplines: Report from the Association of Pulmonary, Critical Care, and Sleep Division Chiefs. Annals Of The American Thoracic Society 2018, 15: 1382-1390. PMID: 30153425, DOI: 10.1513/annalsats.201804-252ar.
- Ye Q, Wu J, Lu Y, Naganawa M, Gallezot JD, Ma T, Liu Y, Tanoue L, Detterbeck F, Blasberg J, Chen MK, Casey M, Carson RE, Liu C. Improved discrimination between benign and malignant LDCT screening-detected lung nodules with dynamic over static 18F-FDG PET as a function of injected dose. Physics In Medicine And Biology 2018, 63: 175015. PMID: 30095083, PMCID: PMC6158045, DOI: 10.1088/1361-6560/aad97f.
- Rivera MP, Tanner NT, Silvestri GA, Detterbeck FC, Tammemägi MC, Young RP, Slatore CG, Caverly TJ, Boyd CM, Braithwaite D, Fathi JT, Gould MK, Iaccarino JM, Malkoski SP, Mazzone PJ, Tanoue LT, Schoenborn NL, Zulueta JJ, Wiener RS. Incorporating Coexisting Chronic Illness into Decisions about Patient Selection for Lung Cancer Screening. An Official American Thoracic Society Research Statement. American Journal Of Respiratory And Critical Care Medicine 2018, 198: e3-e13. PMID: 30004250, DOI: 10.1164/rccm.201805-0986st.
- Detterbeck F, Tanoue L. Chapter 16 Reflections on the Present and Future State of Lung Cancer Research and Management. 2018, 243-249. DOI: 10.1016/b978-0-323-48565-4.00016-3.
- Rothberg B, Das R, Jackson L, Lazowski H, Bai Y, O'Neill D, Roberts S, Rothberg J, Herbst R, Kim A, Boffa D, Rimm D, Detterbeck F, Tanoue L. P1.05-017 The Prognostic Impact of EGFR, KRAS and TP53 Somatic Mutations in Curatively Resected Early-Stage Lung Adenocarcinomas Topic: Translational Research and Biomarkers. Journal Of Thoracic Oncology 2017, 12: s623-s624. DOI: 10.1016/j.jtho.2016.11.801.
- Detterbeck FC, Boffa DJ, Kim AW, Tanoue LT. The Eighth Edition Lung Cancer Stage Classification. CHEST Journal 2016, 151: 193-203. PMID: 27780786, DOI: 10.1016/j.chest.2016.10.010.
- Erb CT, Su KW, Soulos PR, Tanoue LT, Gross CP. Surveillance Practice Patterns after Curative Intent Therapy for Stage I Non-Small-Cell Lung Cancer in the Medicare Population. Lung Cancer 2016, 99: 200-207. PMID: 27565940, PMCID: PMC5003420, DOI: 10.1016/j.lungcan.2016.07.017.
- Tanoue LT. Lung cancer screening. Current Opinion In Pulmonary Medicine 2016, 22: 327-335. PMID: 27159896, DOI: 10.1097/mcp.0000000000000287.
- Detterbeck FC, Marom EM, Arenberg DA, Franklin WA, Nicholson AG, Travis WD, Girard N, Mazzone PJ, Donington JS, Tanoue LT, Rusch VW, Asamura H, Rami-Porta R, Committee I, Goldstraw P, Rami-Porta R, Asamura H, Ball D, Beer D, Beyruti R, Bolejack V, Chansky K, Crowley J, Detterbeck F, Eberhardt W, Edwards J, Galateau-Sallé F, Giroux D, Gleeson F, Groome P, Huang J, Kennedy C, Kim J, Kim Y, Kingsbury L, Kondo H, Krasnik M, Kubota K, Lerut A, Lyons G, Marino M, Marom E, van Meerbeeck J, Mitchell A, Nakano T, Nicholson A, Nowak A, Peake M, Rice T, Rosenzweig K, Ruffini E, Rusch V, Saijo N, Van Schil P, Sculier J, Shemanski L, Stratton K, Suzuki K, Tachimori Y, Thomas C, Travis W, Tsao M, Turrisi A, Vansteenkiste J, Watanabe H, Wu Y, Boards A, Baas P, Erasmus J, Hasegawa S, Inai K, Kernstine K, Kindler H, Krug L, Nackaerts K, Pass H, Rice D, Falkson C, Filosso P, Giaccone G, Kondo K, Lucchi M, Okumura M, Blackstone E, Workgroup M, Flieder D, Godoy M, Goo J, Goodman L, Jett J, de Leyn P, Marchevsky A, MacMahon H, Naidich D, Okada M, Perlman M, Powell C, van Schil P, Warth A. The IASLC Lung Cancer Staging Project: Background Data and Proposals for the Application of TNM Staging Rules to Lung Cancer Presenting as Multiple Nodules with Ground Glass or Lepidic Features or a Pneumonic Type of Involvement in the Forthcoming Eighth Edition of the TNM Classification. Journal Of Thoracic Oncology 2016, 11: 666-680. PMID: 26940527, DOI: 10.1016/j.jtho.2015.12.113.
- Detterbeck FC, Bolejack V, Arenberg DA, Crowley J, Donington JS, Franklin WA, Girard N, Marom EM, Mazzone PJ, Nicholson AG, Rusch VW, Tanoue LT, Travis WD, Asamura H, Rami-Porta R, Committee I, Goldstraw P, Rami-Porta R, Asamura H, Ball D, Beer D, Beyruti R, Bolejack V, Chansky K, Crowley J, Detterbeck F, Eberhardt W, Edwards J, Galateau-Sallé F, Giroux D, Gleeson F, Groome P, Huang J, Kennedy C, Kim J, Kim Y, Kingsbury L, Kondo H, Krasnik M, Kubota K, Lerut A, Lyons G, Marino M, Marom E, van Meerbeeck J, Mitchell A, Nakano T, Nicholson A, Nowak A, Peake M, Rice T, Rosenzweig K, Ruffini E, Rusch V, Saijo N, Van Schil P, Sculier J, Shemanski L, Stratton K, Suzuki K, Tachimori Y, Thomas C, Travis W, Tsao M, Turrisi A, Vansteenkiste J, Watanabe H, Wu Y, Boards A, Baas P, Erasmus J, Hasegawa S, Inai K, Kernstine K, Kindler H, Krug L, Nackaerts K, Pass H, Rice D, Falkson C, Filosso P, Giaccone G, Kondo K, Lucchi M, Okumura M, Blackstone E, Workgroup M, Flieder D, Godoy M, Goo J, Goodman L, Jett J, de Leyn P, Marchevsky A, MacMahon H, Naidich D, Okada M, Perlman M, Powell C, van Schil P, Warth A, Institutions P, Cavaco F, Barrera E, Arca J, Lamelas I, Obrer A, Jorge R, Ball D, Bascom G, Orozco A, Castro M, Blum M, Chimondeguy D, Cvijanovic V, Defranchi S, de Olaiz Navarro B, Campuzano I, Vidueira I, Araujo E, García F, Fong K, Corral G, González S, Gilart J, Arangüena L, Barajas S, Girard P, Goksel T, Budiño M, Casaurrán G, Blanco J, Hernández J, Rodríguez H, Collantes J, Heras M, Elena J, Jakobsen E, Kostas S, Atance P, Ares A, Liao M, Losanovscky M, Lyons G, Magaroles R, De Esteban Júlvez L, Gorospe M, McCaughan B, Kennedy C, Íñiguez R, Sorribes L, Gozalo S, de Arriba C, Delgado M, Alarcón J, Cuesta J, Park J, Pass H, Fernández M, Rosenberg M, Ruffini E, Rusch V, de Cos Escuín J, Vinuesa A, Mitjans M, Strand T, Subotic D, Swisher S, Terra R, Thomas C, Tournoy K, Van Schil P, Velasquez M, Wu Y, Yokoi K. The IASLC Lung Cancer Staging Project: Background Data and Proposals for the Classification of Lung Cancer with Separate Tumor Nodules in the Forthcoming Eighth Edition of the TNM Classification for Lung Cancer. Journal Of Thoracic Oncology 2016, 11: 681-692. PMID: 26940530, DOI: 10.1016/j.jtho.2015.12.114.
- Detterbeck FC, Nicholson AG, Franklin WA, Marom EM, Travis WD, Girard N, Arenberg DA, Bolejack V, Donington JS, Mazzone PJ, Tanoue LT, Rusch VW, Crowley J, Asamura H, Rami-Porta R, Committee I, Goldstraw P, Rami-Porta R, Asamura H, Ball D, Beer D, Beyruti R, Bolejack V, Chansky K, Crowley J, Detterbeck F, Eberhardt W, Edwards J, Galateau-Sallé F, Giroux D, Gleeson F, Groome P, Huang J, Kennedy C, Kim J, Kim Y, Kingsbury L, Kondo H, Krasnik M, Kubota K, Lerut A, Lyons G, Marino M, Marom E, van Meerbeeck J, Mitchell A, Nakano T, Nicholson A, Nowak A, Peake M, Rice T, Rosenzweig K, Ruffini E, Rusch V, Saijo N, Van Schil P, Sculier J, Shemanski L, Stratton K, Suzuki K, Tachimori Y, Thomas C, Travis W, Tsao M, Turrisi A, Vansteenkiste J, Watanabe H, Wu Y, Boards A, Baas P, Erasmus J, Hasegawa S, Inai K, Kernstine K, Kindler H, Krug L, Nackaerts K, Pass H, Rice D, Falkson C, Filosso P, Giaccone G, Kondo K, Lucchi M, Okumura M, Blackstone E, Workgroup M, Flieder D, Godoy M, Goo J, Goodman L, Jett J, de Leyn P, Marchevsky A, MacMahon H, Naidich D, Okada M, Perlman M, Powell C, van Schil P, Warth A, Institutions P, Cavaco F, Barrera E, Arca J, Lamelas I, Obrer A, Jorge R, Ball D, Bascom G, Orozco A, Castro M, Blum M, Chimondeguy D, Cvijanovic V, Defranchi S, de Olaiz Navarro B, Campuzano I, Vidueira I, Araujo E, García F, Fong K, Corral G, González S, Gilart J, Arangüena L, Barajas S, Girard P, Goksel T, Budiño M, Casaurrán G, Blanco J, Hernández J, Rodríguez H, Collantes J, Heras M, Elena J, Jakobsen E, Kostas S, Atance P, Ares A, Liao M, Losanovscky M, Lyons G, Magaroles R, De Esteban Júlvez L, Gorospe M, McCaughan B, Kennedy C, Íñiguez R, Sorribes L, Gozalo S, de Arriba C, Delgado M, Alarcón J, Cuesta J, Park J, Pass H, Fernández M, Rosenberg M, Ruffini E, Rusch V, de Cos Escuín J, Vinuesa A, Mitjans M, Strand T, Subotic D, Swisher S, Terra R, Thomas C, Tournoy K, Van Schil P, Velasquez M, Wu Y, Yokoi K. The IASLC Lung Cancer Staging Project: Summary of Proposals for Revisions of the Classification of Lung Cancers with Multiple Pulmonary Sites of Involvement in the Forthcoming Eighth Edition of the TNM Classification. Journal Of Thoracic Oncology 2016, 11: 639-650. PMID: 26940528, DOI: 10.1016/j.jtho.2016.01.024.
- Detterbeck FC, Franklin WA, Nicholson AG, Girard N, Arenberg DA, Travis WD, Mazzone PJ, Marom EM, Donington JS, Tanoue LT, Rusch VW, Asamura H, Rami-Porta R, Committee I, Goldstraw P, Rami-Porta R, Asamura H, Ball D, Beer D, Beyruti R, Bolejack V, Chansky K, Crowley J, Detterbeck F, Eberhardt W, Edwards J, Galateau-Sallé F, Giroux D, Gleeson F, Groome P, Huang J, Kennedy C, Kim J, Kim Y, Kingsbury L, Kondo H, Krasnik M, Kubota K, Lerut A, Lyons G, Marino M, Marom E, van Meerbeeck J, Mitchell A, Nakano T, Nicholson A, Nowak A, Peake M, Rice T, Rosenzweig K, Ruffini E, Rusch V, Saijo N, Van Schil P, Sculier J, Shemanski L, Stratton K, Suzuki K, Tachimori Y, Thomas C, Travis W, Tsao M, Turrisi A, Vansteenkiste J, Watanabe H, Wu Y, Boards A, Baas P, Erasmus J, Hasegawa S, Inai K, Kernstine K, Kindler H, Krug L, Nackaerts K, Pass H, Rice D, Falkson C, Filosso P, Giaccone G, Kondo K, Lucchi M, Okumura M, Blackstone E, Workgroup M, Flieder D, Godoy M, Goo J, Goodman L, Jett J, de Leyn P, Marchevsky A, MacMahon H, Naidich D, Okada M, Perlman M, Powell C, van Schil P, Warth A. The IASLC Lung Cancer Staging Project: Background Data and Proposed Criteria to Distinguish Separate Primary Lung Cancers from Metastatic Foci in Patients with Two Lung Tumors in the Forthcoming Eighth Edition of the TNM Classification for Lung Cancer. Journal Of Thoracic Oncology 2016, 11: 651-665. PMID: 26944304, DOI: 10.1016/j.jtho.2016.01.025.
- Tanoue LT, Tanner NT, Gould MK, Silvestri GA. Reply: Lung Cancer Screening: The Balance between Harm and Benefit. American Journal Of Respiratory And Critical Care Medicine 2015, 191: 1209-1210. PMID: 25978579, DOI: 10.1164/rccm.201503-0526le.
- Cai S, Qin L, Tanoue L, Hu A, Jia X, Luo H, Chen Y, Chen P, Peng H. Effects of One-Hour Training Course and Spirometry on the Ability of Physicians to Diagnose and Treat Chronic Obstructive Pulmonary Disease. PLOS ONE 2015, 10: e0117348. PMID: 25706774, PMCID: PMC4338104, DOI: 10.1371/journal.pone.0117348.
- Tanoue LT, Tanner NT, Gould MK, Silvestri GA. Lung Cancer Screening. American Journal Of Respiratory And Critical Care Medicine 2015, 191: 19-33. PMID: 25369325, DOI: 10.1164/rccm.201410-1777ci.
- Reid AE, Tanoue L, Detterbeck F, Michaud GC, McCorkle R. The Role of the Advanced Practitioner in a Comprehensive Lung Cancer Screening and Pulmonary Nodule Program. Journal Of The Advanced Practitioner In Oncology 2014, 5: 440-446. PMID: 26328217, PMCID: PMC4530114, DOI: 10.6004/jadpro.2014.5.6.4.
- Erb C, Soulos P, Tanoue L, Gross C. Surveillance Practice Patterns After Curative Intent Therapy for Stage I Non-small Cell Lung Cancer in the Medicare Population. CHEST Journal 2014, 146: 607a. DOI: 10.1378/chest.1992085.
- Reid A, Detterbeck F, Michaud G, Guillod P, Tanoue L. Physicians' Assessment of Lung Cancer Risk and the Influence of Prediction Models on Decisions Relating to Lung Screening. CHEST Journal 2013, 144: 648a-648b. DOI: 10.1378/chest.1662734.
- Detterbeck FC, Postmus PE, Tanoue LT. The Stage Classification of Lung Cancer Diagnosis and Management of Lung Cancer, 3rd ed: American College of Chest Physicians Evidence-Based Clinical Practice Guidelines. CHEST Journal 2013, 143: e191s-e210s. PMID: 23649438, DOI: 10.1378/chest.12-2354.
- Ost DE, Yeung SC, Tanoue LT, Gould MK. Clinical and Organizational Factors in the Initial Evaluation of Patients With Lung Cancer Diagnosis and Management of Lung Cancer, 3rd ed: American College of Chest Physicians Evidence-Based Clinical Practice Guidelines. CHEST Journal 2013, 143: e121s-e141s. PMID: 23649435, PMCID: PMC4694609, DOI: 10.1378/chest.12-2352.
- Silvestri GA, Gonzalez AV, Jantz MA, Margolis ML, Gould MK, Tanoue LT, Harris LJ, Detterbeck FC. Methods for Staging Non-small Cell Lung Cancer Diagnosis and Management of Lung Cancer, 3rd ed: American College of Chest Physicians Evidence-Based Clinical Practice Guidelines. CHEST Journal 2013, 143: e211s-e250s. PMID: 23649440, DOI: 10.1378/chest.12-2355.
- Detterbeck F, Tanoue L, Reid A. National comprehensive cancer network. Journal Of The National Comprehensive Cancer Network 2013, 11: 365-6. PMID: 23584338, DOI: 10.6004/jnccn.2013.0050.
- Vest MT, Herrin J, Soulos PR, Decker RH, Tanoue L, Michaud G, Kim AW, Detterbeck F, Morgensztern D, Gross CP. Use of New Treatment Modalities for Non-small Cell Lung Cancer Care in the Medicare Population. CHEST Journal 2013, 143: 429-435. PMID: 23187634, PMCID: PMC3566996, DOI: 10.1378/chest.12-1149.
- Cai S, Liu F, Hu A, Chen P, Tanoue L. Effect Of Short-Term Education And Spirometry On The Diagnosis Of Chronic Obstructive Pulmonary Disease In 2nd Level Hospitals In Hunan, China. 2012, a3711-a3711. DOI: 10.1164/ajrccm-conference.2012.185.1_meetingabstracts.a3711.
- Vest MT, Tanoue L, Soulos PR, Kim AW, Detterbeck F, Morgensztern D, Gross CP. Thoroughness of Mediastinal Staging in Stage IIIA Non-small Cell Lung Cancer. Journal Of Thoracic Oncology 2012, 7: 188-195. PMID: 22134069, PMCID: PMC3253367, DOI: 10.1097/jto.0b013e318236ecbb.
- Tanoue L, Matthay R. Preface. Clinics In Chest Medicine 2011, 32: xiii-xiv. DOI: 10.1016/j.ccm.2011.08.016.
- Dela Cruz CS, Tanoue LT, Matthay RA. Lung Cancer: Epidemiology, Etiology, and Prevention. Clinics In Chest Medicine 2011, 32: 605-644. PMID: 22054876, PMCID: PMC3864624, DOI: 10.1016/j.ccm.2011.09.001.
- Gettinger S, Tanoue L. Lung Cancer in Older Patients. Respiratory Medicine 2011, 89-109. DOI: 10.1007/978-1-60761-727-3_5.
- Anagnostou VK, Dimou AT, Botsis T, Killiam EJ, Gustavson MD, Homer RJ, Boffa D, Zolota V, Dougenis D, Tanoue L, Gettinger SN, Detterbeck FC, Syrigos KN, Bepler G, Rimm DL. Molecular classification of nonsmall cell lung cancer using a 4‐protein quantitative assay. Cancer 2011, 118: 1607-1618. PMID: 22009766, DOI: 10.1002/cncr.26450.
- Vest M, Tanoue L, Soulos P, Kim A, Gross C. Adoption Of Invasive Clinical Staging Techniques In Stage IIIA Non-Small Cell Lung Cancer Lags Adoption Of Positron Emission Tomography. 2011, a5380-a5380. DOI: 10.1164/ajrccm-conference.2011.183.1_meetingabstracts.a5380.
- Lung CancerTanoue, LT. Lung Cancer. In Yearbook of Pulmonary Medicine 2011. JA Barker, Ed. Elsevier Mosby, Philadelphia. 2011, pp 61-106.
- Lung Cancer in Older Patients.Gettinger S. and Tanoue, LT. Lung Cancer in Older Patients. In Aging and Lung Diseases, M. Pisani Ed, Springer, New York, 2011, pp 89-110.
- Boffa DJ, Detterbeck FC, Smith EJ, Rami-Porta R, Crowley J, Zelterman D, Tanoue L, Kim AW, Goldstraw P. Should the 7th Edition of the Lung Cancer Stage Classification System Change Treatment Algorithms in Non-small Cell Lung Cancer? Journal Of Thoracic Oncology 2010, 5: 1779-1783. PMID: 20975377, DOI: 10.1097/jto.0b013e3181ee80c7.
- Anagnostou V, Botsis T, Killiam E, Zolota V, Dougenis D, Tanoue L, Detterbeck F, Syrigos K, Bepler G, Rimm D. Molecular classification of non-small cell lung cancer using a four protein quantitative assay. Journal Of Clinical Oncology 2010, 28: 10528-10528. DOI: 10.1200/jco.2010.28.15_suppl.10528.
- Anagnostou VK, Lowery FJ, Zolota V, Tzelepi V, Gopinath A, Liceaga C, Panagopoulos N, Frangia K, Tanoue L, Boffa D, Gettinger S, Detterbeck F, Homer RJ, Dougenis D, Rimm DL, Syrigos KN. High expression of BCL-2 predicts favorable outcome in non-small cell lung cancer patients with non squamous histology. BMC Cancer 2010, 10: 186. PMID: 20459695, PMCID: PMC2875218, DOI: 10.1186/1471-2407-10-186.
- Detterbeck FC, Boffa DJ, Tanoue LT, Wilson LD. Details and Difficulties Regarding the New Lung Cancer Staging System. CHEST Journal 2010, 137: 1172-1180. PMID: 20442118, DOI: 10.1378/chest.09-2626.
- Anagnostou V, Kolokytha P, Dimou A, Killiam E, Zolota V, Dougenis D, Frangia K, Tanoue L, Detterbeck F, Syrigos K, Bepler G, Rimm D. Abstract 4643: A novel 3-biomarker quantitative protein assay predicts survival in stage I lung squamous cell carcinomas. Cancer Research 2010, 70: 4643-4643. DOI: 10.1158/1538-7445.am10-4643.
- Lung CancerTanoue. LT. Lung Cancer. In Breathing in America: Diseases, Progress, and Hope. Ed. De Schraufnagel. American Thoracic Society 2010, pp. 109-120.
- DETTERBECK FC, TANOUE LT, BOFFA DJ, 杨 永, 李 志. Anatomy, Biology and Concepts, Pertaining to Lung Cancer Stage Classifcation. Chinese Journal Of Lung Cancer 2010, 13: 1-8. PMID: 20672696, PMCID: PMC6136057, DOI: 10.3779/j.issn.1009-3419.2010.01.01.
- Detterbeck FC, Boffa DJ, Tanoue LT. The New Lung Cancer Staging System. CHEST Journal 2009, 136: 260-271. PMID: 19584208, DOI: 10.1378/chest.08-0978.
- Anagnostou VK, Bepler G, Syrigos KN, Tanoue L, Gettinger S, Homer RJ, Boffa D, Detterbeck F, Rimm DL. High Expression of Mammalian Target of Rapamycin Is Associated with Better Outcome for Patients with Early Stage Lung Adenocarcinoma. Clinical Cancer Research 2009, 15: 4157-4164. PMID: 19509151, DOI: 10.1158/1078-0432.ccr-09-0099.
- Anagnostou V, Lowery F, Syrigos K, Frangia K, Zolota V, Panagopoulos N, Dougenis D, Tanoue L, Detterbeck F, Homer R, Rimm D. Association of expression of bcl-2 with outcome in non-small cell lung cancer. Journal Of Clinical Oncology 2009, 27: e22039-e22039. DOI: 10.1200/jco.2009.27.15_suppl.e22039.
- Detterbeck FC, Tanoue LT, Boffa DJ. Anatomy, Biology and Concepts, Pertaining to Lung Cancer Stage Classification. Journal Of Thoracic Oncology 2009, 4: 437-443. PMID: 19333070, DOI: 10.1097/jto.0b013e31819852ed.
- Tanoue LT, Detterbeck FC. New TNM classification for non-small-cell lung cancer. Expert Review Of Anticancer Therapy 2009, 9: 413-423. PMID: 19374596, DOI: 10.1586/era.09.11.
- Pulmonary Problems in Lung Cancer SurvivorsMiller K and Tanoue LT. Pulmonary Problems in Lung Cancer Survivors. In Medical and Psychosocial Care of the Cancer Survivor. KD Miller, Ed. Jones and Bartlett Publishers, Sudbury, MA. 2009, pp 299-312.
- Lung Cancer: Epidemiology and Carcinogenesis.Dela Cruz C, Tanoue LT, and Matthay RT. Lung Cancer: Epidemiology and Carcinogenesis. In General Thoracic Surgery, Seventh Edition; Shields TW, Locicero J III, Reed CD, and Feins RH, and Rusch VW, Eds. Lippincott, Williams & Wilkins, Philadelphia. 2009, pp 1281-1298.
- Silvestri G, Tanoue L. Lung Cancer: Evolving Concepts. Seminars In Respiratory And Critical Care Medicine 2008, 29: 221-222. PMID: 18506659, DOI: 10.1055/s-2008-1076741.
- Tanoue LT. Staging of Non-Small Cell Lung Cancer. Seminars In Respiratory And Critical Care Medicine 2008, 29: 248-260. PMID: 18506663, DOI: 10.1055/s-2008-1076745.
- Tanoue L. Introduction. Yearbook Of Pulmonary Disease 2008, 2008: 99-101. DOI: 10.1016/s8756-3452(08)70592-9.
- Tanoue LT, Gettinger S. Treatment of Lung Cancer in Older Patients. Clinics In Chest Medicine 2007, 28: 735-749. PMID: 17967291, DOI: 10.1016/j.ccm.2007.08.003.
- Kapoor JR, Monteiro B, Tanoue L, Siegel MD. Massive Intravascular Hemolysis and a Rapidly Fatal Outcome. CHEST Journal 2007, 132: 2016-2019. PMID: 18079238, DOI: 10.1378/chest.07-0853.
- Silvestri GA, Gould MK, Margolis ML, Tanoue LT, McCrory D, Toloza E, Detterbeck F. Noninvasive Staging of Non-small Cell Lung Cancer ACCP Evidenced-Based Clinical Practice Guidelines (2nd Edition). CHEST Journal 2007, 132: 178s-201s. PMID: 17873168, DOI: 10.1378/chest.07-1360.
- Tanoue L. Introduction. Yearbook Of Pulmonary Disease 2007, 2007: 99-101. DOI: 10.1016/s8756-3452(08)70344-x.
- Decker RH, Tanoue LT, Colasanto JM, Detterbeck FC, Wilson LD. Evaluation and definitive management of medically inoperable early stage non-small-cell lung cancer. Part 2: newer treatment modalities. Oncology 2006, 20: 899-905; discussion 905-8, 913. PMID: 16922260.
- Decker RH, Tanoue LT, Colasanto JM, Detterbeck FC, Wilson LD. Evaluation and definitive management of medically inoperable early-stage non-small-cell lung cancer. Part 1: Assessment and conventional radiotherapy. Oncology 2006, 20: 727-36. PMID: 16841796.
- Friedman LN, Nash ER, Bryant J, Henry S, Shi J, D'Amato J, Khaled GH, Russi MB, O'Connor PG, Edberg SC, Pisani MA, Cain HC, Tanoue L, Weissman DN. High Rate of Negative Results of Tuberculin and QuantiFERON Tests Among Individuals With a History of Positive Skin Test Results. Infection Control And Hospital Epidemiology 2006, 27: 436-441. PMID: 16671022, DOI: 10.1086/503690.
- Noble PW, Tanoue L, Homer R. Case Study Review. CHEST Journal 2005, 128: 540s-546s. PMID: 16304245, DOI: 10.1378/chest.128.5_suppl_1.540s.
- Cabot R, Harris N, McNeely W, Shepard J, Ebeling S, Ellender S, Peters C, Tanoue L, Mark E. Case 1-2003 — A 43-Year-Old Man with Fever and Night Sweats. New England Journal Of Medicine 2003, 348: 151-161. PMID: 12519926, DOI: 10.1056/nejmcpc020026.
- Silvestri GA, Tanoue LT, Margolis ML, Barker J, Detterbeck F. The Noninvasive Staging of Non-small Cell Lung Cancer* The Guidelines. CHEST Journal 2003, 123: 147s-156s. PMID: 12527574, DOI: 10.1378/chest.123.1_suppl.147s.
- Tanoue LT. Pulmonary Hypertension in the Collagen Vascular Diseases. Seminars In Respiratory And Critical Care Medicine 2003, 24: 287-296. PMID: 16088549, DOI: 10.1055/s-2003-41089.
- Tanoue LT, Ponn RB. Therapy for stage I and stage II non-small cell lung cancer. Clinics In Chest Medicine 2002, 23: 173-190. PMID: 11901910, DOI: 10.1016/s0272-5231(03)00067-4.
- Tanoue LT. CIGARETTE SMOKING AND WOMEN'S RESPIRATORY HEALTH. Clinics In Chest Medicine 2000, 21: 47-65. PMID: 10763089, DOI: 10.1016/s0272-5231(05)70007-1.
- Tanoue L. Preoperative Evaluation of the High-Risk Surgical Patient for Lung Cancer Resection. Seminars In Respiratory And Critical Care Medicine 2000, Volume 21: 421-432. PMID: 16088753, DOI: 10.1055/s-2000-9404.
- Salloum E, Tanoue L, Wackers F, Zelterman D, Hu G, Cooper D. Assessment of Cardiac and Pulmonary Function in Adult Patients with Hodgkin's Disease Treated with ABVD or MOPP/ABVD Plus Adjuvant Low-Dose Mediastinal Irradiation. Cancer Investigation 1999, 17: 171-180. PMID: 10099655, DOI: 10.3109/07357909909021418.
- Tanoue L. PULMONARY MANIFESTATIONS OF RHEUMATOID ARTHRITIS. Clinics In Chest Medicine 1998, 19: 667-685. PMID: 9917959, DOI: 10.1016/s0272-5231(05)70109-x.
- Quin JA, Letsou GV, Tanoue LT, Matthay RA, Higgins RS, Baldwin JC. Use of neodymium yttrium aluminum garnet laser in long-term palliation of airway obstruction. Connecticut Medicine 1995, 59: 407-12. PMID: 7545564.
- Redlich C, Van Bennekum A, Wirth J, Blaner W, Carter D, Tanoue L, Holm C, Cullen M. Vitamin A Chemoprevention of Lung Cancer. Advances In Experimental Medicine And Biology 1995, 375: 17-29. PMID: 7645426, DOI: 10.1007/978-1-4899-0949-7_2.
- Tanoue L. Lung transplantation. Lung 1992, 170: 187-200. PMID: 1522739, DOI: 10.1007/bf00174116.
- Tanoue L. Pulmonary involvement in collagen vascular disease. Journal Of Thoracic Imaging 1992, 7: 62. PMID: 1578527, DOI: 10.1097/00005382-199203000-00008.
- Tanoue LT, Aronson PS, Bia MJ. The effect of diuretics on extrarenal potassium tolerance. The Yale Journal Of Biology And Medicine 1982, 55: 421-8. PMID: 7183021, PMCID: PMC2596565.
- Pulmonary Toxicity Associated With Chemotherapeutic Agents.Tanoue LT and McArdle J. Pulmonary Toxicity Associated With Chemotherapeutic Agents. In Fishman’s Textbook of Pulmonary Disorders and Diseases, 3rd Edition, A.P.Fishman, Ed., McGraw Hill, Inc., New York, pp 1067-1102.
- Lung Cancer: Clinical Evaluation and StagingTanoue, LT. “Lung Cancer: Clinical Evaluation and Staging”, in Comprehensive Respiratory Medicine, Ed. SG Spiro SG and G Silvestri, Mosby, London, in press.
- Winchester Center for Lung DiseaseFitkin Memorial Pavilion789 Howard AvenueNew Haven, CT 06519
- Yale Thoracic Oncology ProgramSmilow Cancer Hospital at Yale New Haven35 Park Street, Ste 4th Floor Multispecialty Care CenterNew Haven, CT 06511
- Winchester Center for Lung DiseaseFitkin Memorial Pavilion789 Howard AvenueNew Haven, CT 06519
- Yale Thoracic Oncology ProgramSmilow Cancer Hospital at Yale New Haven35 Park Street, Ste 4th Floor Multispecialty Care CenterNew Haven, CT 06511