Jennifer McNiff, MD
Biography
Accuracy is everything for dermatopathologist Jennifer McNiff, MD, who is the medical director of Dermatopathology at Yale Medicine. As a doctor who is highly trained in both dermatology and pathology, she runs a lab where skin samples from all over the world are sent for diagnoses. “We are trained to recognize every skin condition—from rashes to tumors,” says Dr. McNiff.
She and her team work very closely together in the lab, giving patients the benefit of more than one specialist’s expertise. “Our team of dermatopathologists reviews complex and challenging cases together daily, in a consensus conference at a multi-headed microscope,” Dr. McNiff says.
Dr. McNiff enjoys both helping patients and their treating physicians by using her experience to identify even subtle cell changes that are indicators of disease. Often the identifying features of skin diseases, including cancers, are so slight that it takes the know-how of leading experts to make the right diagnosis so that patients can receive the care they need.
“For me, it is all about the patient and the knowledge that we are positioned to help both patients and their treating physicians by generating accurate and timely diagnoses,” she says.
The past President of the American Society of Dermatopathology, Dr. McNiff is frequently invited to speak at national and international meetings.
Titles
- Professor of Dermatology and Pathology
- Director, Yale Dermatopathology Laboratory
- Section Chief, Dermatopathology
Education & Training
- FellowMedical College of Virginia, Richmond, VA (1992)
- Chief ResidentUniversity of Virginia Health Services Center, Charlottesville, VA (1991)
- ResidentUniversity of Virginia Health Services Center, Charlottesville, VA (1990)
- MDUniversity of Vermont (1986)
Additional Information
- Founder's Award: American Society of Dermatopathology (2024)
- University of Vermont Award for Academic Achievement: University of Vermont College of Medicine (2021)
- Walter R Nickel Award for Excellence in Teaching Dermatopathology: American Society of Dermatopathology (2011)
- AB of Pathology, Dermatopathology (1993)
- AB of Pathology, Anatomic & Clinical Pathology (1991)
- Yale University School of Medicine (2020): Interim Chair, Pathology
- American Society of Dermatopathology (2012 - 2016): Committee Member
- American Society of Dermatopathology (2011 - 2012): President
- International Society of Dermatopathology (2009 - 2013): Executive Committee Member
- American Society of Dermatopathology (2008 - 2013): Board of Directors
- American Society of Dermatopathology (2004 - 2009): Program Director for National Meeting 2009, in charge of all content for meeting
- Vesely M, Garritano J, Damsky W, McNiff J, Chen L. 748 PD-1H/VISTA agonism as a potential therapy for cutaneous lupus. Journal Of Investigative Dermatology 2024, 144: s131. DOI: 10.1016/j.jid.2024.06.764.
- Tang H, Laskin W, Luan Y, McNiff J, Zhan H. Adenocarcinoma of anogenital mammary gland type arising from encapsulated papillary carcinoma: A rare vulvar tumor mimicking breast carcinoma. Journal Of Cutaneous Pathology 2024, 51: 604-608. PMID: 38711196, DOI: 10.1111/cup.14639.
- Turner N, Ko C, McNiff J, Galan A. Pitfalls of PRAME Immunohistochemistry in a Large Series of Melanocytic and Nonmelanocytic Lesions With Literature Review. American Journal Of Dermatopathology 2024, 46: 21-30. PMID: 37982498, DOI: 10.1097/dad.0000000000002584.
- Johnston A, Roy S, McNiff J, Petrazzuoli M. Granulomatous secondary syphilis with pulmonary involvement. JAAD Case Reports 2023, 44: 23-26. PMID: 38292581, PMCID: PMC10824677, DOI: 10.1016/j.jdcr.2023.11.017.
- Wong J, Roy S, McNiff J, Xu M. IRF8 in Conjunction With CD123 and CD20 to Distinguish Lupus Erythematosus Panniculitis From Subcutaneous Panniculitis-like T-Cell Lymphoma. The American Journal Of Surgical Pathology 2023, 47: 1425-1431. PMID: 37767989, DOI: 10.1097/pas.0000000000002133.
- Little A, Chen P, Vesely M, Khan R, Fiedler J, Garritano J, Islam F, McNiff J, Craft J. HIF-1 regulates pathogenic cytotoxic T cells in lupus skin disease. JCI Insight 2023, 8: e166076. PMID: 37526979, PMCID: PMC10543720, DOI: 10.1172/jci.insight.166076.
- Tang H, McNiff J, Glusac E, Ko C. PRAME‐negativity in sclerosing nevi with pseudomelanomatous features supports classification as an indolent lesion. Journal Of Cutaneous Pathology 2023, 50: 1001-1005. PMID: 37565491, DOI: 10.1111/cup.14505.
- Seli D, Ellis K, Goldust M, Shah K, Hu R, Zhou J, McNiff J, Choate K. Association of Somatic ATP2A2 Damaging Variants With Grover Disease. JAMA Dermatology 2023, 159: 745-749. PMID: 37195706, PMCID: PMC10193258, DOI: 10.1001/jamadermatol.2023.1139.
- Tang H, Panse G, Braddock D, Perincheri S, Xu M, McNiff J. IRF8 may be a useful marker for blastic plasmacytoid dendritic cell neoplasm, especially with weak CD123 expression. Journal Of Cutaneous Pathology 2023, 50: 595-600. PMID: 37082914, DOI: 10.1111/cup.14439.
- Roy S, Panse G, McNiff J. PRAME immunohistochemistry can distinguish melanocytic pseudonests of lichenoid reactions from melanoma in situ. Journal Of Cutaneous Pathology 2023, 50: 450-454. PMID: 36789669, DOI: 10.1111/cup.14407.
- Choi R, Bhullar S, McNiff J, Persico J, Leventhal J. A rare case of viral-associated trichodysplasia spinulosa in a patient with chronic lymphocytic leukemia. International Journal Of Women's Dermatology 2023, 9: e069. PMID: 36846188, PMCID: PMC9949812, DOI: 10.1097/jw9.0000000000000069.
- Sacirbegovic F, Günther M, Greco A, Zhao D, Wang X, Zhou M, Rosenberger S, Oberbarnscheidt M, Held W, McNiff J, Jain D, Höfer T, Shlomchik W. Graft-versus-host disease is locally maintained in target tissues by resident progenitor-like T cells. Immunity 2023, 56: 369-385.e6. PMID: 36720219, PMCID: PMC10182785, DOI: 10.1016/j.immuni.2023.01.003.
- Tsang M, McNiff J. Interface change in early mycosis fungoides: A potential mimicker of benign dermatoses. Journal Of Cutaneous Pathology 2022, 50: 266-274. PMID: 36444501, DOI: 10.1111/cup.14369.
- Roy S, Sarhan J, Liu X, Murphy M, Bunick C, Choate K, Damsky W, McNiff J. Inguinal patch in mpox (monkeypox) virus infection and eccrine syringometaplasia: report of two cases with in situ hybridization and electron microscopy findings. British Journal Of Dermatology 2022, 188: 574-576. PMID: 36763786, DOI: 10.1093/bjd/ljac146.
- A case of eosinophilic dermatosis of hematologic malignancy with tissue-based Th2 cytokine profilingXu S, Singh K, McNiff J, Damsky W, Gehlhausen J. A case of eosinophilic dermatosis of hematologic malignancy with tissue-based Th2 cytokine profiling. JAAD Case Reports 2022, 30: 5-7. PMID: 36345409, PMCID: PMC9636011, DOI: 10.1016/j.jdcr.2022.09.020.
- Choi R, Garritano J, Laird M, Johnston M, Tkachenko E, Damsky W, Little AJ, McNiff J, Girardi M, Nelson CA. Treatment of toxic epidermal necrolysis and concurrent COVID-19-associated hyperinflammatory syndrome with systemic corticosteroids and etanercept. JAAD Case Reports 2022, 29: 139-141. PMID: 36160836, PMCID: PMC9485430, DOI: 10.1016/j.jdcr.2022.09.009.
- Vesely M, Martinez-Morilla S, Gehlhausen JR, McNiff JM, Whang PG, Rimm D, Ko CJ. Not all well-differentiated cutaneous squamous cell carcinomas are equal: Tumors with disparate biologic behavior have differences in protein expression via digital spatial profiling. Journal Of The American Academy Of Dermatology 2022, 87: 695-698. PMID: 35398219, DOI: 10.1016/j.jaad.2022.03.057.
- Belzer A, McNiff JM, Leventhal JS. Skin eruption involving bilateral breasts following radiation therapy for invasive ductal carcinoma of the left breast. International Journal Of Women's Dermatology 2022, 8: e016. PMID: 35619675, PMCID: PMC9112382, DOI: 10.1097/jw9.0000000000000016.
- Choi R, Ring N, McNiff JM, Wilson LD, Martin K, Leventhal J. Treatment of multifocal cutaneous Rosai-Dorfman disease with radiotherapy. JAAD Case Reports 2022, 23: 106-108. PMID: 35495976, PMCID: PMC9039858, DOI: 10.1016/j.jdcr.2022.03.027.
- Dehner CA, Ruff WE, Greiling T, Pereira MS, Redanz S, McNiff J, Girardi M, Kriegel MA. Malignant T Cell Activation by a Bacillus Species Isolated from Cutaneous T-Cell Lymphoma Lesions. JID Innovations 2021, 2: 100084. PMID: 35199089, PMCID: PMC8844718, DOI: 10.1016/j.xjidi.2021.100084.
- Kim SR, McNiff JM, Ko CJ. Clustered intraepidermal lymphocytes and Langerhans cell microgranulomas are consistently observed in hyperkeratotic palmoplantar eczema compared with palmoplantar psoriasis and mycosis fungoides palmaris et plantaris. Journal Of The American Academy Of Dermatology 2021, 87: 884-886. PMID: 34883152, DOI: 10.1016/j.jaad.2021.11.057.
- Xie CB, Ring N, Damsky W, McNiff JM, Olino K, Odell I. Squamous cell carcinoma arising in long-standing necrobiosis lipoidica treated with radical resection and split-thickness skin graft. JAAD Case Reports 2021, 19: 90-93. PMID: 35024397, PMCID: PMC8724883, DOI: 10.1016/j.jdcr.2021.11.005.
- Li P, Panse G, Singh S, Krivda SJ, McNiff JM. Cutaneous involvement by plasma cell myeloma with aberrant CD4 expression. Journal Of Cutaneous Pathology 2021, 49: 921-924. PMID: 36222211, DOI: 10.1111/cup.14141.
- Wang JX, Yu SH, Hall RR, McNiff J, Leffell DJ, Kibbi N. Verrucous candidiasis of the lip: A harbinger of squamous cell carcinoma. JAAD Case Reports 2021, 16: 168-170. PMID: 34646926, PMCID: PMC8498090, DOI: 10.1016/j.jdcr.2021.08.015.
- Li P, Barbieri A, Walther Z, McNiff J, Panse G. Epidermotropic metastasis of squamous cell carcinoma of the tonsil: A case report with molecular confirmation. Journal Of Cutaneous Pathology 2021, 48: 1514-1519. PMID: 34302376, DOI: 10.1111/cup.14108.
- Leasure A, Cowper S, McNiff J, Cohen J. Generalized eczematous reactions to the Pfizer‐BioNTech COVID‐19 vaccine. Journal Of The European Academy Of Dermatology And Venereology 2021, 35: e716-e717. PMID: 34236729, PMCID: PMC8447468, DOI: 10.1111/jdv.17494.
- Mendoza H, Goodwin J, Gehlhausen J, Odell I, McNiff J, Gnanapandithan K. New bullous lesions in a 72-year-old woman. Cleveland Clinic Journal Of Medicine 2021, 88: 319-324. PMID: 34078615, DOI: 10.3949/ccjm.88a.20180.
- Wang A, Fogel AL, Murphy MJ, Panse G, McGeary MK, McNiff JM, Bosenberg M, Vesely MD, Cohen JM, Ko CJ, King BA, Damsky W. Cytokine RNA In Situ Hybridization Permits Individualized Molecular Phenotyping in Biopsies of Psoriasis and Atopic Dermatitis. JID Innovations 2021, 1: 100021. PMID: 34909719, PMCID: PMC8659380, DOI: 10.1016/j.xjidi.2021.100021.
- Ko CJ, Gehlhausen JR, McNiff JM. Leukocytoclastic Vasculitis and Microvascular Occlusion Key Concepts for the Working Pathologist. Surgical Pathology Clinics 2021, 14: 309-325. PMID: 34023108, DOI: 10.1016/j.path.2021.01.006.
- Wang MZ, McNiff JM, McCalmont TH, LeBoit PE. Desmoplastic Trichoepithelioma With Pseudocarcinomatous Hyperplasia: A Folliculosebaceous Neoplasm in Young Persons. American Journal Of Dermatopathology 2021, 43: 788-793. PMID: 33899770, DOI: 10.1097/dad.0000000000001922.
- Totonchy MB, McNiff JM, Suozzi KC, Leffell DJ, Christensen SR. A Histopathologic Scoring System for Perineural Invasion Correlates With Adverse Outcomes in Patients With Cutaneous Squamous Cell Carcinoma. Dermatologic Surgery 2021, 47: 445-451. PMID: 33795563, DOI: 10.1097/dss.0000000000002923.
- Panse G, McNiff JM. Lichenoid dermatoses with pseudomelanocytic nests vs inflamed melanoma in situ: A comparative study. Journal Of Cutaneous Pathology 2021, 48: 745-749. PMID: 33350494, DOI: 10.1111/cup.13945.
- Singh K, Wang A, Heald P, McNiff JM, Suozzi K, King B, Leventhal J, Damsky W. Treatment of angiolupoid sarcoidosis with tofacitinib ointment 2% and pulsed dye laser therapy. JAAD Case Reports 2020, 7: 122-124. PMID: 33426249, PMCID: PMC7777455, DOI: 10.1016/j.jdcr.2020.11.016.
- Ko CJ, Harigopal M, Gehlhausen JR, Bosenberg M, McNiff JM, Damsky W. Discordant anti‐SARS‐CoV‐2 spike protein and RNA staining in cutaneous perniotic lesions suggests endothelial deposition of cleaved spike protein. Journal Of Cutaneous Pathology 2020, 48: 47-52. PMID: 32895985, DOI: 10.1111/cup.13866.
- Ko CJ, Harigopal M, Damsky W, Gehlhausen JR, Bosenberg M, Patrignelli R, McNiff JM. Perniosis during the COVID‐19 pandemic: Negative anti‐SARS‐CoV‐2 immunohistochemistry in six patients and comparison to perniosis before the emergence of SARS‐CoV‐2. Journal Of Cutaneous Pathology 2020, 47: 997-1002. PMID: 32745281, PMCID: PMC7436569, DOI: 10.1111/cup.13830.
- Panse G, Subtil A, McNiff JM, Glusac EJ, Ko CJ, Galan A, Myung P, Xu ML. Cutaneous Involvement in Plasma Cell Myeloma. American Journal Of Clinical Pathology 2020, 155: 106-116. PMID: 32885235, DOI: 10.1093/ajcp/aqaa122.
- Roy SF, McNiff JM. Epidermolytic Acanthoma: Findings of a Large Retrospective Study. International Journal Of Gynecological Pathology 2020, 40: e4-e4. PMID: 33290356, DOI: 10.1097/pgp.0000000000000672.
- Roy SF, Ko CJ, Moeckel GW, Mcniff JM. Hypergranulotic dyscornification: 30 cases of a striking epithelial reaction pattern. Journal Of Cutaneous Pathology 2019, 46: 742-747. PMID: 31157457, DOI: 10.1111/cup.13522.
- Vyas NS, Charifa A, Desman GT, Goldberg M, Singh R, Phelps RG, McNiff JM. Observational Study Examining the Diagnostic Practice of Ki67 Staining for Melanocytic Lesions. American Journal Of Dermatopathology 2019, Publish Ahead of Print: &na;. PMID: 31233404, DOI: 10.1097/dad.0000000000001379.
- Roy SF, Dong D, Myung P, McNiff JM. Multinucleate cell angiohistiocytoma: A clinicopathologic study of 62 cases and proposed diagnostic criteria. Journal Of Cutaneous Pathology 2019, 46: 563-569. PMID: 30927287, DOI: 10.1111/cup.13463.
- Lim Y, Bacchiocchi A, Qiu J, Bruckner A, Bercovitch L, Narayan D, McNiff J, Ko C, Robinson-Bostom L, Antaya R, Halaban R, Choate K. 513 GNA14 somatic mutation causes congenital and sporadic vascular tumors by MAPK activation. Journal Of Investigative Dermatology 2017, 137: s88. DOI: 10.1016/j.jid.2017.02.533.
- Levinsohn J, Sugarman J, McNiff J, Freiden I, Antaya R, Choate K. 514 Somatic mutations in nevus comedonicus identify nek9 as a determinant of follicular keratinocyte cell fate. Journal Of Investigative Dermatology 2017, 137: s88. DOI: 10.1016/j.jid.2017.02.534.
- Alomari AK, Glusac EJ, McNiff JM. p40 is a more specific marker than p63 for cutaneous poorly differentiated squamous cell carcinoma. Journal Of Cutaneous Pathology 2014, 41: 839-845. PMID: 25263848, DOI: 10.1111/cup.12388.
- Alomari A, McNiff JM. The significance of eosinophils in hypertrophic lichen planus. Journal Of Cutaneous Pathology 2014, 41: 347-352. PMID: 24325780, DOI: 10.1111/cup.12275.
- Ko CJ, McNiff JM. Punctate pemphigus: an underreported direct immunofluorescence pattern. Journal Of Cutaneous Pathology 2013, 41: 293-296. PMID: 24372009, DOI: 10.1111/cup.12272.
- PD-L1 and PD-L2 Protect The Heart In a T-Cell Receptor Transgenic Model Of Graft-Versus Host DiseaseJuchem K, Anderson B, Zhang C, Sharpe A, McNiff J, Demetris A, Shlomchik M, Shlomchik W. PD-L1 and PD-L2 Protect The Heart In a T-Cell Receptor Transgenic Model Of Graft-Versus Host Disease. Blood 2013, 122: 4479. DOI: 10.1182/blood.v122.21.4479.4479.
- Jedrych J, Leffell D, McNiff JM. Desmoplastic trichoepithelioma with perineural involvement: a series of seven cases. Journal Of Cutaneous Pathology 2012, 39: 317-323. PMID: 22335590, DOI: 10.1111/j.1600-0560.2012.01876.x.
- Juchem K, Anderson B, Zhang C, McNiff J, Demetris A, Caton A, Shlomchik W, Shlomchik M. A repertoire independent and cell intrinsic defect in murine GVHD induction by effector memory T cells (169.6). The Journal Of Immunology 2011, 186: 169.6-169.6. DOI: 10.4049/jimmunol.186.supp.169.6.
- McNiff J, Kim J, Antaya R. Linear acral lesions in an infant. Journal Of The American Academy Of Dermatology 2010, 63: e67-e68. DOI: 10.1016/j.jaad.2009.08.019.
- Wilkinson K, Anderson B, McNiff J, Demetris A, Shlomchik W, Shlomchik M. A New TCR Transgenic Model of GVHD Reveals That, Independent of Repertoire, Effector Memory T Cells Are Severely Limited, and Central Memory T Cells Somewhat Limited, in Their Ability to Cause GVHD. Blood 2009, 114: 233. DOI: 10.1182/blood.v114.22.233.233.
- Wang X, Martone C, Demetris A, McNiff J, Shlomchik W. Donor APCs Promote Gvhd in MHC-Mismatched Transplants by Indirectly Presenting Host Minor Histocompatibility Antigens. Blood 2009, 114: 689. DOI: 10.1182/blood.v114.22.689.689.
- Li H, Matte-Martone C, Demetris A, McNiff J, Jain D, Shlomchik W. Redundant Mechanisms for Dendritic Cell Activation in GVHD Induction: Signalings Via TLRs, TNF-α, IL-1 and CD40 Are Not Required. Blood 2008, 112: 3509. DOI: 10.1182/blood.v112.11.3509.3509.
- Li H, Kaplan D, Demetris A, McNiff J, Shlomchik M, Shlomchik W. Recipient Langerhans Cells Are Neither Required Nor Sufficient for GVHD Induction in MHC-Matched Allogeneic BMT, but a Langerin+ Cell Is a Pivotal Regulator of Langerhans Cell Turnover Post Transplantation. Blood 2008, 112: 3511. DOI: 10.1182/blood.v112.11.3511.3511.
- Galan A, McNiff J. Reply. Journal Of Cutaneous Pathology 2008, 35: 1164-1164. DOI: 10.1111/j.1600-0560.2007.00951.x.
- Bennett J, McNiff J. Post‐Irradiation Vascular Proliferations: Potential Mimic of Kaposi’s Sarcoma. Journal Of Cutaneous Pathology 2008, 32: 76-76. DOI: 10.1111/j.0303-6987.2005.0320t.x.
- McNiff J, Subtil A, Cowper S, Lazova R, Glusac E. Reply. Journal Of Cutaneous Pathology 2006, 33: 764-764. DOI: 10.1111/j.1600-0560.2006.00547.x.
- Shiao S, McNiff J, Masunaga T, Tamura K, Pober J. IMMUNOMODULATION BY HUMANIZED ANTI-CD28 MAB FK734. Transplantation 2006, 82: 905. DOI: 10.1097/00007890-200607152-02554.
- Shlomchik W, Matte C, Liu J, Jain D, McNiff J. CD8+ but Not CD4+ T Cells Require Cognate Interactions with Target Tissues To Mediate GVHD across Only Minor H Antigens but CD4+ and CD8+ T Cells Both Require Direct Leukemic Contact for GVL. Blood 2005, 106: 580. DOI: 10.1182/blood.v106.11.580.580.
- McNiff J. Practical Immunopathology of the Skin. American Journal Of Dermatopathology 2004, 26: 514. DOI: 10.1097/00000372-200412000-00013.
- Anderson B, McNiff J, Jain D, Blazar B, Shlomchik W, Shlomchik M. Distinct Roles for Donor and Host Antigen Presenting Cells and Costimulatory Molecules in Murine Chronic Graft-Vs-Host Disease: Requirements Depend on Target Organ. Blood 2004, 104: 3059. DOI: 10.1182/blood.v104.11.3059.3059.
- Kirkiles-Smith N, Mahboubi K, Plescia J, McNiff J, Karras J, Schechner J, Altieri D, Pober J. IL-11 PROTECTS HUMAN MICROVASCULAR ENDOTHELIUM FROM ALLOINJURY IN VIVO BY INDUCTION OF SURVIVIN EXPRESSION. Cardiovascular Pathology 2004, 13: 112. DOI: 10.1016/j.carpath.2004.03.336.
- Smith BD, Glusac EJ, McNiff JM, Smith GL, Heald PW, Cooper DL, Wilson LD. Primary Cutaneous B-Cell Lymphoma Treated With Radiotherapy: A Comparison of the European Organization for Research and Treatment of Cancer and the WHO Classification Systems. Journal Of Clinical Oncology 2004, 22: 634-639. PMID: 14966086, DOI: 10.1200/jco.2004.08.044.
- Peng S, Cappadona J, Mcniff J, Madaio M, Owen M, Hayday A, Craft J. Pathogenesis of autoimmunity in αβ T cell-deficient lupus-prone mice. Clinical & Experimental Immunology 2001, 111: 107-116. PMID: 9472669, PMCID: PMC1904839, DOI: 10.1046/j.1365-2249.1998.00424.x.
- Liu J, Anderson B, Robert M, McNiff J, Emerson S, Shlomchik W, Shlomchik M. Selective T-cell subset ablation demonstrates a role for T1 and T2 cells in ongoing acute graft-versus-host disease: a model system for the reversal of disease. Blood 2001, 98: 3367-3375. PMID: 11719376, DOI: 10.1182/blood.v98.12.3367.
- Schaffer J, McNiff J, Bolognia J. Cerebral Mass Due to Neurocutaneous Melanosis: Eight Years Later. Pediatric Dermatology 2001, 18: 369-377. PMID: 11737677, DOI: 10.1046/j.1525-1470.2001.01961.x.
- Chan O, Paliwal V, McNiff J, Park S, Bendelac A, Shlomchik M. Deficiency in β2-Microglobulin, But Not CD1, Accelerates Spontaneous Lupus Skin Disease While Inhibiting Nephritis in MRL-Faslpr Mice: An Example of Disease Regulation at the Organ Level. The Journal Of Immunology 2001, 167: 2985-2990. PMID: 11509649, DOI: 10.4049/jimmunol.167.5.2985.
- Chen T, Yan W, Wells R, Rimm D, McNiff J, Leffell D, Reiss M. Novel inactivating mutations of transforming growth factor‐β type I receptor gene in head‐and‐neck cancer metastases. International Journal Of Cancer 2001, 93: 653-661. PMID: 11477574, DOI: 10.1002/ijc.1381.
- Schaffer J, Davidson D, McNiff J, Bolognia J. Perinuclear antineutrophilic cytoplasmic antibody-positive cutaneous polyarteritis nodosa associated with minocycline therapy for acne vulgaris. Journal Of The American Academy Of Dermatology 2001, 44: 198-206. PMID: 11174376, DOI: 10.1067/mjd.2001.112218.
- Lazova R, McNiff J, Glusac E. Under The Microscope Surgeons, Pathologists, and Melanocytic Nevi. Clinics In Plastic Surgery 2000, 27: 323-329. PMID: 10941556, DOI: 10.1016/s0094-1298(20)32731-0.
- Cerroni L, Arzberger E, Puütz B, Hoüfler G, Metze D, Sander C, Rose C, Wolf P, Ruütten A, McNiff J, Kerl H. Primary cutaneous follicle center cell lymphoma with follicular growth pattern. Blood 2000, 95: 3922-3928. PMID: 10845929, DOI: 10.1182/blood.v95.12.3922.
- Cerroni L, Arzberger E, Pütz B, Höfler G, Metze D, Sander C, Rose C, Wolf P, Rütten A, McNiff J, Kerl H. Primary cutaneous follicle center cell lymphoma with follicular growth pattern. Blood 2000, 95: 3922-3928. DOI: 10.1182/blood.v95.12.3922.012k08_3922_3928.
- Kirkiles-Smith N, Tereb D, Kim R, McNiff J, Schechner J, Lorber M, Pober J, Tellides G. Human TNF Can Induce Nonspecific Inflammatory and Human Immune-Mediated Microvascular Injury of Pig Skin Xenografts in Immunodeficient Mouse Hosts. The Journal Of Immunology 2000, 164: 6601-6609. PMID: 10843720, DOI: 10.4049/jimmunol.164.12.6601.
- Scaramuzzino D, McNiff J, Bessen D. Humanized In Vivo Model for Streptococcal Impetigo. Infection And Immunity 2000, 68: 2880-2887. PMID: 10768985, PMCID: PMC97500, DOI: 10.1128/iai.68.5.2880-2887.2000.
- Grossman D, McNiff J, Li F, Altieri D. Expression and Targeting of the Apoptosis Inhibitor, Survivin, in Human Melanoma. Journal Of Investigative Dermatology 1999, 113: 1076-1081. PMID: 10594755, DOI: 10.1046/j.1523-1747.1999.00776.x.
- Grossman D, McNiff J, Li F, Altieri D. Expression of the apoptosis inhibitor, survivin, in nonmelanoma skin cancer and gene targeting in a keratinocyte cell line. Laboratory Investigation 1999, 79: 1121-6. PMID: 10496530.
- McNiff J, Glusac E, Lazova R, Carroll C. Morphea Limited to the Superficial Reticular Dermis: An Underrecognized Histologic Phenomenon. American Journal Of Dermatopathology 1999, 21: 315-319. PMID: 10446770, DOI: 10.1097/00000372-199908000-00001.
- Shlomchik W, Couzens M, Tang C, McNiff J, Robert M, Liu J, Shlomchik M, Emerson S. Prevention of Graft Versus Host Disease by Inactivation of Host Antigen-Presenting Cells. Science 1999, 285: 412-415. PMID: 10411505, DOI: 10.1126/science.285.5426.412.
- Girardi M, Federman G, McNiff J. Familial Multiple Basaloid Follicular Hamartomas: A Report of Two Affected Sisters. Pediatric Dermatology 1999, 16: 281-284. PMID: 10469412, DOI: 10.1046/j.1525-1470.1999.00061.x.
- Asgari M, Haggerty J, McNiff J, Milstone L, Schwartz P. Expression and localization of thymidine phosphorylase/platelet‐derived endothelial cell growth factor in skin and cutaneous tumors. Journal Of Cutaneous Pathology 1999, 26: 287-294. PMID: 10472757, DOI: 10.1111/j.1600-0560.1999.tb01846.x.
- Chan E, Gat U, McNiff J, Fuchs E. A common human skin tumour is caused by activating mutations in β-catenin. Nature Genetics 1999, 21: 410-413. PMID: 10192393, DOI: 10.1038/7747.
- McNiff J, Eisen R, Glusac E. Immunohistochemical comparison of cutaneous lymphadenoma, trichoblastoma, and basal cell carcinoma: support for classification of lymphadenoma as a variant of trichoblastoma. Journal Of Cutaneous Pathology 1999, 26: 119-124. PMID: 10235376, DOI: 10.1111/j.1600-0560.1999.tb01815.x.
- Girardi M, McNiff J, Heald P. Extracorporeal photochemotherapy in human and murine graft-versus-host disease. Journal Of Dermatological Science 1999, 19: 106-113. PMID: 10098701, DOI: 10.1016/s0923-1811(98)00066-8.
- Glusac E, McNiff J. Epithelioid Cell Histiocytoma: A Simulant of Vascular and Melanocytic Neoplasms. American Journal Of Dermatopathology 1999, 21: 1-7. PMID: 10027517, DOI: 10.1097/00000372-199902000-00001.
- Gasparro FP, Liao B, Foley PJ, Wang XM, McNiff J. Psoralen photochemotherapy, clinical efficacy, and photomutagenicity: The role of molecular epidemiology in minimizing risks. Environmental And Molecular Mutagenesis 1998, 31: 105-112. PMID: 9544188, DOI: 10.1002/(sici)1098-2280(1998)31:2<105::aid-em2>3.0.co;2-l.
- Murray A, Schechner J, Epperson D, Sultan P, McNiff J, Hughes C, Lorber M, Askenase P, Pober J. Dermal Microvascular Injury in the Human Peripheral Blood Lymphocyte Reconstituted-Severe Combined Immunodeficient (HuPBL-SCID) Mouse/Skin Allograft Model Is T Cell Mediated and Inhibited by a Combination of Cyclosporine and Rapamycin. American Journal Of Pathology 1998, 153: 627-638. PMID: 9708821, PMCID: PMC1852982, DOI: 10.1016/s0002-9440(10)65604-0.
- McNiff J, Schechner J, Crotty P, Glusac E. Mycosis Fungoides Palmaris et Plantaris or Acral Pagetoid Reticulosis? American Journal Of Dermatopathology 1998, 20: 271-275. PMID: 9650701, DOI: 10.1097/00000372-199806000-00009.
- Schechner J, Edelson R, McNiff J, Heald P, Pober J. Expression of integrin α4β7 on epidermotropic cutaneous T cells in cutaneous T cell lymphoma and spongiotic dermatitis. Journal Of Dermatological Science 1998, 16: s168. DOI: 10.1016/s0923-1811(98)84004-8.
- Gloor P, Kim M, McNiff J, Wolfley D. Discoid Lupus Erythematosus Presenting as Asymmetric Posterior Blepharitis. American Journal Of Ophthalmology 1997, 124: 707-709. PMID: 9372736, DOI: 10.1016/s0002-9394(14)70920-1.
- Sultan P, Murray A, McNiff J, Lorber M, Askenase P, Bothwell A, Pober J. Pig but not human interferon-γ initiates human cell-mediated rejection of pig tissue in vivo. Proceedings Of The National Academy Of Sciences Of The United States Of America 1997, 94: 8767-8772. PMID: 9238052, PMCID: PMC23121, DOI: 10.1073/pnas.94.16.8767.
- Wang X, McNiff J, Klump V, Asgari M, Gasparro F. An Unexpected Spectrum of p53 Mutations from Squamous Cell Carcinomas in Psoriasis Patients Treated with PUVA. Photochemistry And Photobiology 1997, 66: 294-299. PMID: 9277151, DOI: 10.1111/j.1751-1097.1997.tb08658.x.
- Sultan P, Schechner J, McNiff J, Hochman P, Hughes C, Lorber M, Askenase P, Pober J. Blockade of CD2-LFA-3 interactions protects human skin allografts in immunodeficient mouse/human chimeras. Nature Biotechnology 1997, 15: 759-762. PMID: 9255790, DOI: 10.1038/nbt0897-759.
- Huether MJ, Bbolognia J, Imaeda S, McNiff JM. Bullous pemphigoid associated with eosinophilic pustules. British Journal Of Dermatology 1997, 136: 641-642. PMID: 9155985, DOI: 10.1111/j.1365-2133.1997.tb02172.x.
- McNiff J, Cooper D, Howe G, Crotty P, Tallini G, Crouch J, Eisen R. Lymphomatoid granulomatosis of the skin and lung. An angiocentric T-cell-rich B-cell lymphoproliferative disorder. JAMA Dermatology 1996, 132: 1464-70. PMID: 8961876, DOI: 10.1001/archderm.132.12.1464.
- McNiff J, Cooper D, Howe G, Crotty P, Tallini G, Crouch J, Eisen R. Lymphomatoid Granulomatosis of the Skin and Lung: An Angiocentric T-Cell-Rich B-Cell Lymphoproliferative Disorder. JAMA Dermatology 1996, 132: 1464-1470. DOI: 10.1001/archderm.1996.03890360054010.
Biography
Accuracy is everything for dermatopathologist Jennifer McNiff, MD, who is the medical director of Dermatopathology at Yale Medicine. As a doctor who is highly trained in both dermatology and pathology, she runs a lab where skin samples from all over the world are sent for diagnoses. “We are trained to recognize every skin condition—from rashes to tumors,” says Dr. McNiff.
She and her team work very closely together in the lab, giving patients the benefit of more than one specialist’s expertise. “Our team of dermatopathologists reviews complex and challenging cases together daily, in a consensus conference at a multi-headed microscope,” Dr. McNiff says.
Dr. McNiff enjoys both helping patients and their treating physicians by using her experience to identify even subtle cell changes that are indicators of disease. Often the identifying features of skin diseases, including cancers, are so slight that it takes the know-how of leading experts to make the right diagnosis so that patients can receive the care they need.
“For me, it is all about the patient and the knowledge that we are positioned to help both patients and their treating physicians by generating accurate and timely diagnoses,” she says.
The past President of the American Society of Dermatopathology, Dr. McNiff is frequently invited to speak at national and international meetings.
Titles
- Professor of Dermatology and Pathology
- Director, Yale Dermatopathology Laboratory
- Section Chief, Dermatopathology
Education & Training
- FellowMedical College of Virginia, Richmond, VA (1992)
- Chief ResidentUniversity of Virginia Health Services Center, Charlottesville, VA (1991)
- ResidentUniversity of Virginia Health Services Center, Charlottesville, VA (1990)
- MDUniversity of Vermont (1986)
Additional Information
- Founder's Award: American Society of Dermatopathology (2024)
- University of Vermont Award for Academic Achievement: University of Vermont College of Medicine (2021)
- Walter R Nickel Award for Excellence in Teaching Dermatopathology: American Society of Dermatopathology (2011)
- AB of Pathology, Dermatopathology (1993)
- AB of Pathology, Anatomic & Clinical Pathology (1991)
- Yale University School of Medicine (2020): Interim Chair, Pathology
- American Society of Dermatopathology (2012 - 2016): Committee Member
- American Society of Dermatopathology (2011 - 2012): President
- International Society of Dermatopathology (2009 - 2013): Executive Committee Member
- American Society of Dermatopathology (2008 - 2013): Board of Directors
- American Society of Dermatopathology (2004 - 2009): Program Director for National Meeting 2009, in charge of all content for meeting
- Vesely M, Garritano J, Damsky W, McNiff J, Chen L. 748 PD-1H/VISTA agonism as a potential therapy for cutaneous lupus. Journal Of Investigative Dermatology 2024, 144: s131. DOI: 10.1016/j.jid.2024.06.764.
- Tang H, Laskin W, Luan Y, McNiff J, Zhan H. Adenocarcinoma of anogenital mammary gland type arising from encapsulated papillary carcinoma: A rare vulvar tumor mimicking breast carcinoma. Journal Of Cutaneous Pathology 2024, 51: 604-608. PMID: 38711196, DOI: 10.1111/cup.14639.
- Turner N, Ko C, McNiff J, Galan A. Pitfalls of PRAME Immunohistochemistry in a Large Series of Melanocytic and Nonmelanocytic Lesions With Literature Review. American Journal Of Dermatopathology 2024, 46: 21-30. PMID: 37982498, DOI: 10.1097/dad.0000000000002584.
- Johnston A, Roy S, McNiff J, Petrazzuoli M. Granulomatous secondary syphilis with pulmonary involvement. JAAD Case Reports 2023, 44: 23-26. PMID: 38292581, PMCID: PMC10824677, DOI: 10.1016/j.jdcr.2023.11.017.
- Wong J, Roy S, McNiff J, Xu M. IRF8 in Conjunction With CD123 and CD20 to Distinguish Lupus Erythematosus Panniculitis From Subcutaneous Panniculitis-like T-Cell Lymphoma. The American Journal Of Surgical Pathology 2023, 47: 1425-1431. PMID: 37767989, DOI: 10.1097/pas.0000000000002133.
- Little A, Chen P, Vesely M, Khan R, Fiedler J, Garritano J, Islam F, McNiff J, Craft J. HIF-1 regulates pathogenic cytotoxic T cells in lupus skin disease. JCI Insight 2023, 8: e166076. PMID: 37526979, PMCID: PMC10543720, DOI: 10.1172/jci.insight.166076.
- Tang H, McNiff J, Glusac E, Ko C. PRAME‐negativity in sclerosing nevi with pseudomelanomatous features supports classification as an indolent lesion. Journal Of Cutaneous Pathology 2023, 50: 1001-1005. PMID: 37565491, DOI: 10.1111/cup.14505.
- Seli D, Ellis K, Goldust M, Shah K, Hu R, Zhou J, McNiff J, Choate K. Association of Somatic ATP2A2 Damaging Variants With Grover Disease. JAMA Dermatology 2023, 159: 745-749. PMID: 37195706, PMCID: PMC10193258, DOI: 10.1001/jamadermatol.2023.1139.
- Tang H, Panse G, Braddock D, Perincheri S, Xu M, McNiff J. IRF8 may be a useful marker for blastic plasmacytoid dendritic cell neoplasm, especially with weak CD123 expression. Journal Of Cutaneous Pathology 2023, 50: 595-600. PMID: 37082914, DOI: 10.1111/cup.14439.
- Roy S, Panse G, McNiff J. PRAME immunohistochemistry can distinguish melanocytic pseudonests of lichenoid reactions from melanoma in situ. Journal Of Cutaneous Pathology 2023, 50: 450-454. PMID: 36789669, DOI: 10.1111/cup.14407.
- Choi R, Bhullar S, McNiff J, Persico J, Leventhal J. A rare case of viral-associated trichodysplasia spinulosa in a patient with chronic lymphocytic leukemia. International Journal Of Women's Dermatology 2023, 9: e069. PMID: 36846188, PMCID: PMC9949812, DOI: 10.1097/jw9.0000000000000069.
- Sacirbegovic F, Günther M, Greco A, Zhao D, Wang X, Zhou M, Rosenberger S, Oberbarnscheidt M, Held W, McNiff J, Jain D, Höfer T, Shlomchik W. Graft-versus-host disease is locally maintained in target tissues by resident progenitor-like T cells. Immunity 2023, 56: 369-385.e6. PMID: 36720219, PMCID: PMC10182785, DOI: 10.1016/j.immuni.2023.01.003.
- Tsang M, McNiff J. Interface change in early mycosis fungoides: A potential mimicker of benign dermatoses. Journal Of Cutaneous Pathology 2022, 50: 266-274. PMID: 36444501, DOI: 10.1111/cup.14369.
- Roy S, Sarhan J, Liu X, Murphy M, Bunick C, Choate K, Damsky W, McNiff J. Inguinal patch in mpox (monkeypox) virus infection and eccrine syringometaplasia: report of two cases with in situ hybridization and electron microscopy findings. British Journal Of Dermatology 2022, 188: 574-576. PMID: 36763786, DOI: 10.1093/bjd/ljac146.
- A case of eosinophilic dermatosis of hematologic malignancy with tissue-based Th2 cytokine profilingXu S, Singh K, McNiff J, Damsky W, Gehlhausen J. A case of eosinophilic dermatosis of hematologic malignancy with tissue-based Th2 cytokine profiling. JAAD Case Reports 2022, 30: 5-7. PMID: 36345409, PMCID: PMC9636011, DOI: 10.1016/j.jdcr.2022.09.020.
- Choi R, Garritano J, Laird M, Johnston M, Tkachenko E, Damsky W, Little AJ, McNiff J, Girardi M, Nelson CA. Treatment of toxic epidermal necrolysis and concurrent COVID-19-associated hyperinflammatory syndrome with systemic corticosteroids and etanercept. JAAD Case Reports 2022, 29: 139-141. PMID: 36160836, PMCID: PMC9485430, DOI: 10.1016/j.jdcr.2022.09.009.
- Vesely M, Martinez-Morilla S, Gehlhausen JR, McNiff JM, Whang PG, Rimm D, Ko CJ. Not all well-differentiated cutaneous squamous cell carcinomas are equal: Tumors with disparate biologic behavior have differences in protein expression via digital spatial profiling. Journal Of The American Academy Of Dermatology 2022, 87: 695-698. PMID: 35398219, DOI: 10.1016/j.jaad.2022.03.057.
- Belzer A, McNiff JM, Leventhal JS. Skin eruption involving bilateral breasts following radiation therapy for invasive ductal carcinoma of the left breast. International Journal Of Women's Dermatology 2022, 8: e016. PMID: 35619675, PMCID: PMC9112382, DOI: 10.1097/jw9.0000000000000016.
- Choi R, Ring N, McNiff JM, Wilson LD, Martin K, Leventhal J. Treatment of multifocal cutaneous Rosai-Dorfman disease with radiotherapy. JAAD Case Reports 2022, 23: 106-108. PMID: 35495976, PMCID: PMC9039858, DOI: 10.1016/j.jdcr.2022.03.027.
- Dehner CA, Ruff WE, Greiling T, Pereira MS, Redanz S, McNiff J, Girardi M, Kriegel MA. Malignant T Cell Activation by a Bacillus Species Isolated from Cutaneous T-Cell Lymphoma Lesions. JID Innovations 2021, 2: 100084. PMID: 35199089, PMCID: PMC8844718, DOI: 10.1016/j.xjidi.2021.100084.
- Kim SR, McNiff JM, Ko CJ. Clustered intraepidermal lymphocytes and Langerhans cell microgranulomas are consistently observed in hyperkeratotic palmoplantar eczema compared with palmoplantar psoriasis and mycosis fungoides palmaris et plantaris. Journal Of The American Academy Of Dermatology 2021, 87: 884-886. PMID: 34883152, DOI: 10.1016/j.jaad.2021.11.057.
- Xie CB, Ring N, Damsky W, McNiff JM, Olino K, Odell I. Squamous cell carcinoma arising in long-standing necrobiosis lipoidica treated with radical resection and split-thickness skin graft. JAAD Case Reports 2021, 19: 90-93. PMID: 35024397, PMCID: PMC8724883, DOI: 10.1016/j.jdcr.2021.11.005.
- Li P, Panse G, Singh S, Krivda SJ, McNiff JM. Cutaneous involvement by plasma cell myeloma with aberrant CD4 expression. Journal Of Cutaneous Pathology 2021, 49: 921-924. PMID: 36222211, DOI: 10.1111/cup.14141.
- Wang JX, Yu SH, Hall RR, McNiff J, Leffell DJ, Kibbi N. Verrucous candidiasis of the lip: A harbinger of squamous cell carcinoma. JAAD Case Reports 2021, 16: 168-170. PMID: 34646926, PMCID: PMC8498090, DOI: 10.1016/j.jdcr.2021.08.015.
- Li P, Barbieri A, Walther Z, McNiff J, Panse G. Epidermotropic metastasis of squamous cell carcinoma of the tonsil: A case report with molecular confirmation. Journal Of Cutaneous Pathology 2021, 48: 1514-1519. PMID: 34302376, DOI: 10.1111/cup.14108.
- Leasure A, Cowper S, McNiff J, Cohen J. Generalized eczematous reactions to the Pfizer‐BioNTech COVID‐19 vaccine. Journal Of The European Academy Of Dermatology And Venereology 2021, 35: e716-e717. PMID: 34236729, PMCID: PMC8447468, DOI: 10.1111/jdv.17494.
- Mendoza H, Goodwin J, Gehlhausen J, Odell I, McNiff J, Gnanapandithan K. New bullous lesions in a 72-year-old woman. Cleveland Clinic Journal Of Medicine 2021, 88: 319-324. PMID: 34078615, DOI: 10.3949/ccjm.88a.20180.
- Wang A, Fogel AL, Murphy MJ, Panse G, McGeary MK, McNiff JM, Bosenberg M, Vesely MD, Cohen JM, Ko CJ, King BA, Damsky W. Cytokine RNA In Situ Hybridization Permits Individualized Molecular Phenotyping in Biopsies of Psoriasis and Atopic Dermatitis. JID Innovations 2021, 1: 100021. PMID: 34909719, PMCID: PMC8659380, DOI: 10.1016/j.xjidi.2021.100021.
- Ko CJ, Gehlhausen JR, McNiff JM. Leukocytoclastic Vasculitis and Microvascular Occlusion Key Concepts for the Working Pathologist. Surgical Pathology Clinics 2021, 14: 309-325. PMID: 34023108, DOI: 10.1016/j.path.2021.01.006.
- Wang MZ, McNiff JM, McCalmont TH, LeBoit PE. Desmoplastic Trichoepithelioma With Pseudocarcinomatous Hyperplasia: A Folliculosebaceous Neoplasm in Young Persons. American Journal Of Dermatopathology 2021, 43: 788-793. PMID: 33899770, DOI: 10.1097/dad.0000000000001922.
- Totonchy MB, McNiff JM, Suozzi KC, Leffell DJ, Christensen SR. A Histopathologic Scoring System for Perineural Invasion Correlates With Adverse Outcomes in Patients With Cutaneous Squamous Cell Carcinoma. Dermatologic Surgery 2021, 47: 445-451. PMID: 33795563, DOI: 10.1097/dss.0000000000002923.
- Panse G, McNiff JM. Lichenoid dermatoses with pseudomelanocytic nests vs inflamed melanoma in situ: A comparative study. Journal Of Cutaneous Pathology 2021, 48: 745-749. PMID: 33350494, DOI: 10.1111/cup.13945.
- Singh K, Wang A, Heald P, McNiff JM, Suozzi K, King B, Leventhal J, Damsky W. Treatment of angiolupoid sarcoidosis with tofacitinib ointment 2% and pulsed dye laser therapy. JAAD Case Reports 2020, 7: 122-124. PMID: 33426249, PMCID: PMC7777455, DOI: 10.1016/j.jdcr.2020.11.016.
- Ko CJ, Harigopal M, Gehlhausen JR, Bosenberg M, McNiff JM, Damsky W. Discordant anti‐SARS‐CoV‐2 spike protein and RNA staining in cutaneous perniotic lesions suggests endothelial deposition of cleaved spike protein. Journal Of Cutaneous Pathology 2020, 48: 47-52. PMID: 32895985, DOI: 10.1111/cup.13866.
- Ko CJ, Harigopal M, Damsky W, Gehlhausen JR, Bosenberg M, Patrignelli R, McNiff JM. Perniosis during the COVID‐19 pandemic: Negative anti‐SARS‐CoV‐2 immunohistochemistry in six patients and comparison to perniosis before the emergence of SARS‐CoV‐2. Journal Of Cutaneous Pathology 2020, 47: 997-1002. PMID: 32745281, PMCID: PMC7436569, DOI: 10.1111/cup.13830.
- Panse G, Subtil A, McNiff JM, Glusac EJ, Ko CJ, Galan A, Myung P, Xu ML. Cutaneous Involvement in Plasma Cell Myeloma. American Journal Of Clinical Pathology 2020, 155: 106-116. PMID: 32885235, DOI: 10.1093/ajcp/aqaa122.
- Roy SF, McNiff JM. Epidermolytic Acanthoma: Findings of a Large Retrospective Study. International Journal Of Gynecological Pathology 2020, 40: e4-e4. PMID: 33290356, DOI: 10.1097/pgp.0000000000000672.
- Roy SF, Ko CJ, Moeckel GW, Mcniff JM. Hypergranulotic dyscornification: 30 cases of a striking epithelial reaction pattern. Journal Of Cutaneous Pathology 2019, 46: 742-747. PMID: 31157457, DOI: 10.1111/cup.13522.
- Vyas NS, Charifa A, Desman GT, Goldberg M, Singh R, Phelps RG, McNiff JM. Observational Study Examining the Diagnostic Practice of Ki67 Staining for Melanocytic Lesions. American Journal Of Dermatopathology 2019, Publish Ahead of Print: &na;. PMID: 31233404, DOI: 10.1097/dad.0000000000001379.
- Roy SF, Dong D, Myung P, McNiff JM. Multinucleate cell angiohistiocytoma: A clinicopathologic study of 62 cases and proposed diagnostic criteria. Journal Of Cutaneous Pathology 2019, 46: 563-569. PMID: 30927287, DOI: 10.1111/cup.13463.
- Lim Y, Bacchiocchi A, Qiu J, Bruckner A, Bercovitch L, Narayan D, McNiff J, Ko C, Robinson-Bostom L, Antaya R, Halaban R, Choate K. 513 GNA14 somatic mutation causes congenital and sporadic vascular tumors by MAPK activation. Journal Of Investigative Dermatology 2017, 137: s88. DOI: 10.1016/j.jid.2017.02.533.
- Levinsohn J, Sugarman J, McNiff J, Freiden I, Antaya R, Choate K. 514 Somatic mutations in nevus comedonicus identify nek9 as a determinant of follicular keratinocyte cell fate. Journal Of Investigative Dermatology 2017, 137: s88. DOI: 10.1016/j.jid.2017.02.534.
- Alomari AK, Glusac EJ, McNiff JM. p40 is a more specific marker than p63 for cutaneous poorly differentiated squamous cell carcinoma. Journal Of Cutaneous Pathology 2014, 41: 839-845. PMID: 25263848, DOI: 10.1111/cup.12388.
- Alomari A, McNiff JM. The significance of eosinophils in hypertrophic lichen planus. Journal Of Cutaneous Pathology 2014, 41: 347-352. PMID: 24325780, DOI: 10.1111/cup.12275.
- Ko CJ, McNiff JM. Punctate pemphigus: an underreported direct immunofluorescence pattern. Journal Of Cutaneous Pathology 2013, 41: 293-296. PMID: 24372009, DOI: 10.1111/cup.12272.
- PD-L1 and PD-L2 Protect The Heart In a T-Cell Receptor Transgenic Model Of Graft-Versus Host DiseaseJuchem K, Anderson B, Zhang C, Sharpe A, McNiff J, Demetris A, Shlomchik M, Shlomchik W. PD-L1 and PD-L2 Protect The Heart In a T-Cell Receptor Transgenic Model Of Graft-Versus Host Disease. Blood 2013, 122: 4479. DOI: 10.1182/blood.v122.21.4479.4479.
- Jedrych J, Leffell D, McNiff JM. Desmoplastic trichoepithelioma with perineural involvement: a series of seven cases. Journal Of Cutaneous Pathology 2012, 39: 317-323. PMID: 22335590, DOI: 10.1111/j.1600-0560.2012.01876.x.
- Juchem K, Anderson B, Zhang C, McNiff J, Demetris A, Caton A, Shlomchik W, Shlomchik M. A repertoire independent and cell intrinsic defect in murine GVHD induction by effector memory T cells (169.6). The Journal Of Immunology 2011, 186: 169.6-169.6. DOI: 10.4049/jimmunol.186.supp.169.6.
- McNiff J, Kim J, Antaya R. Linear acral lesions in an infant. Journal Of The American Academy Of Dermatology 2010, 63: e67-e68. DOI: 10.1016/j.jaad.2009.08.019.
- Wilkinson K, Anderson B, McNiff J, Demetris A, Shlomchik W, Shlomchik M. A New TCR Transgenic Model of GVHD Reveals That, Independent of Repertoire, Effector Memory T Cells Are Severely Limited, and Central Memory T Cells Somewhat Limited, in Their Ability to Cause GVHD. Blood 2009, 114: 233. DOI: 10.1182/blood.v114.22.233.233.
- Wang X, Martone C, Demetris A, McNiff J, Shlomchik W. Donor APCs Promote Gvhd in MHC-Mismatched Transplants by Indirectly Presenting Host Minor Histocompatibility Antigens. Blood 2009, 114: 689. DOI: 10.1182/blood.v114.22.689.689.
- Li H, Matte-Martone C, Demetris A, McNiff J, Jain D, Shlomchik W. Redundant Mechanisms for Dendritic Cell Activation in GVHD Induction: Signalings Via TLRs, TNF-α, IL-1 and CD40 Are Not Required. Blood 2008, 112: 3509. DOI: 10.1182/blood.v112.11.3509.3509.
- Li H, Kaplan D, Demetris A, McNiff J, Shlomchik M, Shlomchik W. Recipient Langerhans Cells Are Neither Required Nor Sufficient for GVHD Induction in MHC-Matched Allogeneic BMT, but a Langerin+ Cell Is a Pivotal Regulator of Langerhans Cell Turnover Post Transplantation. Blood 2008, 112: 3511. DOI: 10.1182/blood.v112.11.3511.3511.
- Galan A, McNiff J. Reply. Journal Of Cutaneous Pathology 2008, 35: 1164-1164. DOI: 10.1111/j.1600-0560.2007.00951.x.
- Bennett J, McNiff J. Post‐Irradiation Vascular Proliferations: Potential Mimic of Kaposi’s Sarcoma. Journal Of Cutaneous Pathology 2008, 32: 76-76. DOI: 10.1111/j.0303-6987.2005.0320t.x.
- McNiff J, Subtil A, Cowper S, Lazova R, Glusac E. Reply. Journal Of Cutaneous Pathology 2006, 33: 764-764. DOI: 10.1111/j.1600-0560.2006.00547.x.
- Shiao S, McNiff J, Masunaga T, Tamura K, Pober J. IMMUNOMODULATION BY HUMANIZED ANTI-CD28 MAB FK734. Transplantation 2006, 82: 905. DOI: 10.1097/00007890-200607152-02554.
- Shlomchik W, Matte C, Liu J, Jain D, McNiff J. CD8+ but Not CD4+ T Cells Require Cognate Interactions with Target Tissues To Mediate GVHD across Only Minor H Antigens but CD4+ and CD8+ T Cells Both Require Direct Leukemic Contact for GVL. Blood 2005, 106: 580. DOI: 10.1182/blood.v106.11.580.580.
- McNiff J. Practical Immunopathology of the Skin. American Journal Of Dermatopathology 2004, 26: 514. DOI: 10.1097/00000372-200412000-00013.
- Anderson B, McNiff J, Jain D, Blazar B, Shlomchik W, Shlomchik M. Distinct Roles for Donor and Host Antigen Presenting Cells and Costimulatory Molecules in Murine Chronic Graft-Vs-Host Disease: Requirements Depend on Target Organ. Blood 2004, 104: 3059. DOI: 10.1182/blood.v104.11.3059.3059.
- Kirkiles-Smith N, Mahboubi K, Plescia J, McNiff J, Karras J, Schechner J, Altieri D, Pober J. IL-11 PROTECTS HUMAN MICROVASCULAR ENDOTHELIUM FROM ALLOINJURY IN VIVO BY INDUCTION OF SURVIVIN EXPRESSION. Cardiovascular Pathology 2004, 13: 112. DOI: 10.1016/j.carpath.2004.03.336.
- Smith BD, Glusac EJ, McNiff JM, Smith GL, Heald PW, Cooper DL, Wilson LD. Primary Cutaneous B-Cell Lymphoma Treated With Radiotherapy: A Comparison of the European Organization for Research and Treatment of Cancer and the WHO Classification Systems. Journal Of Clinical Oncology 2004, 22: 634-639. PMID: 14966086, DOI: 10.1200/jco.2004.08.044.
- Peng S, Cappadona J, Mcniff J, Madaio M, Owen M, Hayday A, Craft J. Pathogenesis of autoimmunity in αβ T cell-deficient lupus-prone mice. Clinical & Experimental Immunology 2001, 111: 107-116. PMID: 9472669, PMCID: PMC1904839, DOI: 10.1046/j.1365-2249.1998.00424.x.
- Liu J, Anderson B, Robert M, McNiff J, Emerson S, Shlomchik W, Shlomchik M. Selective T-cell subset ablation demonstrates a role for T1 and T2 cells in ongoing acute graft-versus-host disease: a model system for the reversal of disease. Blood 2001, 98: 3367-3375. PMID: 11719376, DOI: 10.1182/blood.v98.12.3367.
- Schaffer J, McNiff J, Bolognia J. Cerebral Mass Due to Neurocutaneous Melanosis: Eight Years Later. Pediatric Dermatology 2001, 18: 369-377. PMID: 11737677, DOI: 10.1046/j.1525-1470.2001.01961.x.
- Chan O, Paliwal V, McNiff J, Park S, Bendelac A, Shlomchik M. Deficiency in β2-Microglobulin, But Not CD1, Accelerates Spontaneous Lupus Skin Disease While Inhibiting Nephritis in MRL-Faslpr Mice: An Example of Disease Regulation at the Organ Level. The Journal Of Immunology 2001, 167: 2985-2990. PMID: 11509649, DOI: 10.4049/jimmunol.167.5.2985.
- Chen T, Yan W, Wells R, Rimm D, McNiff J, Leffell D, Reiss M. Novel inactivating mutations of transforming growth factor‐β type I receptor gene in head‐and‐neck cancer metastases. International Journal Of Cancer 2001, 93: 653-661. PMID: 11477574, DOI: 10.1002/ijc.1381.
- Schaffer J, Davidson D, McNiff J, Bolognia J. Perinuclear antineutrophilic cytoplasmic antibody-positive cutaneous polyarteritis nodosa associated with minocycline therapy for acne vulgaris. Journal Of The American Academy Of Dermatology 2001, 44: 198-206. PMID: 11174376, DOI: 10.1067/mjd.2001.112218.
- Lazova R, McNiff J, Glusac E. Under The Microscope Surgeons, Pathologists, and Melanocytic Nevi. Clinics In Plastic Surgery 2000, 27: 323-329. PMID: 10941556, DOI: 10.1016/s0094-1298(20)32731-0.
- Cerroni L, Arzberger E, Puütz B, Hoüfler G, Metze D, Sander C, Rose C, Wolf P, Ruütten A, McNiff J, Kerl H. Primary cutaneous follicle center cell lymphoma with follicular growth pattern. Blood 2000, 95: 3922-3928. PMID: 10845929, DOI: 10.1182/blood.v95.12.3922.
- Cerroni L, Arzberger E, Pütz B, Höfler G, Metze D, Sander C, Rose C, Wolf P, Rütten A, McNiff J, Kerl H. Primary cutaneous follicle center cell lymphoma with follicular growth pattern. Blood 2000, 95: 3922-3928. DOI: 10.1182/blood.v95.12.3922.012k08_3922_3928.
- Kirkiles-Smith N, Tereb D, Kim R, McNiff J, Schechner J, Lorber M, Pober J, Tellides G. Human TNF Can Induce Nonspecific Inflammatory and Human Immune-Mediated Microvascular Injury of Pig Skin Xenografts in Immunodeficient Mouse Hosts. The Journal Of Immunology 2000, 164: 6601-6609. PMID: 10843720, DOI: 10.4049/jimmunol.164.12.6601.
- Scaramuzzino D, McNiff J, Bessen D. Humanized In Vivo Model for Streptococcal Impetigo. Infection And Immunity 2000, 68: 2880-2887. PMID: 10768985, PMCID: PMC97500, DOI: 10.1128/iai.68.5.2880-2887.2000.
- Grossman D, McNiff J, Li F, Altieri D. Expression and Targeting of the Apoptosis Inhibitor, Survivin, in Human Melanoma. Journal Of Investigative Dermatology 1999, 113: 1076-1081. PMID: 10594755, DOI: 10.1046/j.1523-1747.1999.00776.x.
- Grossman D, McNiff J, Li F, Altieri D. Expression of the apoptosis inhibitor, survivin, in nonmelanoma skin cancer and gene targeting in a keratinocyte cell line. Laboratory Investigation 1999, 79: 1121-6. PMID: 10496530.
- McNiff J, Glusac E, Lazova R, Carroll C. Morphea Limited to the Superficial Reticular Dermis: An Underrecognized Histologic Phenomenon. American Journal Of Dermatopathology 1999, 21: 315-319. PMID: 10446770, DOI: 10.1097/00000372-199908000-00001.
- Shlomchik W, Couzens M, Tang C, McNiff J, Robert M, Liu J, Shlomchik M, Emerson S. Prevention of Graft Versus Host Disease by Inactivation of Host Antigen-Presenting Cells. Science 1999, 285: 412-415. PMID: 10411505, DOI: 10.1126/science.285.5426.412.
- Girardi M, Federman G, McNiff J. Familial Multiple Basaloid Follicular Hamartomas: A Report of Two Affected Sisters. Pediatric Dermatology 1999, 16: 281-284. PMID: 10469412, DOI: 10.1046/j.1525-1470.1999.00061.x.
- Asgari M, Haggerty J, McNiff J, Milstone L, Schwartz P. Expression and localization of thymidine phosphorylase/platelet‐derived endothelial cell growth factor in skin and cutaneous tumors. Journal Of Cutaneous Pathology 1999, 26: 287-294. PMID: 10472757, DOI: 10.1111/j.1600-0560.1999.tb01846.x.
- Chan E, Gat U, McNiff J, Fuchs E. A common human skin tumour is caused by activating mutations in β-catenin. Nature Genetics 1999, 21: 410-413. PMID: 10192393, DOI: 10.1038/7747.
- McNiff J, Eisen R, Glusac E. Immunohistochemical comparison of cutaneous lymphadenoma, trichoblastoma, and basal cell carcinoma: support for classification of lymphadenoma as a variant of trichoblastoma. Journal Of Cutaneous Pathology 1999, 26: 119-124. PMID: 10235376, DOI: 10.1111/j.1600-0560.1999.tb01815.x.
- Girardi M, McNiff J, Heald P. Extracorporeal photochemotherapy in human and murine graft-versus-host disease. Journal Of Dermatological Science 1999, 19: 106-113. PMID: 10098701, DOI: 10.1016/s0923-1811(98)00066-8.
- Glusac E, McNiff J. Epithelioid Cell Histiocytoma: A Simulant of Vascular and Melanocytic Neoplasms. American Journal Of Dermatopathology 1999, 21: 1-7. PMID: 10027517, DOI: 10.1097/00000372-199902000-00001.
- Gasparro FP, Liao B, Foley PJ, Wang XM, McNiff J. Psoralen photochemotherapy, clinical efficacy, and photomutagenicity: The role of molecular epidemiology in minimizing risks. Environmental And Molecular Mutagenesis 1998, 31: 105-112. PMID: 9544188, DOI: 10.1002/(sici)1098-2280(1998)31:2<105::aid-em2>3.0.co;2-l.
- Murray A, Schechner J, Epperson D, Sultan P, McNiff J, Hughes C, Lorber M, Askenase P, Pober J. Dermal Microvascular Injury in the Human Peripheral Blood Lymphocyte Reconstituted-Severe Combined Immunodeficient (HuPBL-SCID) Mouse/Skin Allograft Model Is T Cell Mediated and Inhibited by a Combination of Cyclosporine and Rapamycin. American Journal Of Pathology 1998, 153: 627-638. PMID: 9708821, PMCID: PMC1852982, DOI: 10.1016/s0002-9440(10)65604-0.
- McNiff J, Schechner J, Crotty P, Glusac E. Mycosis Fungoides Palmaris et Plantaris or Acral Pagetoid Reticulosis? American Journal Of Dermatopathology 1998, 20: 271-275. PMID: 9650701, DOI: 10.1097/00000372-199806000-00009.
- Schechner J, Edelson R, McNiff J, Heald P, Pober J. Expression of integrin α4β7 on epidermotropic cutaneous T cells in cutaneous T cell lymphoma and spongiotic dermatitis. Journal Of Dermatological Science 1998, 16: s168. DOI: 10.1016/s0923-1811(98)84004-8.
- Gloor P, Kim M, McNiff J, Wolfley D. Discoid Lupus Erythematosus Presenting as Asymmetric Posterior Blepharitis. American Journal Of Ophthalmology 1997, 124: 707-709. PMID: 9372736, DOI: 10.1016/s0002-9394(14)70920-1.
- Sultan P, Murray A, McNiff J, Lorber M, Askenase P, Bothwell A, Pober J. Pig but not human interferon-γ initiates human cell-mediated rejection of pig tissue in vivo. Proceedings Of The National Academy Of Sciences Of The United States Of America 1997, 94: 8767-8772. PMID: 9238052, PMCID: PMC23121, DOI: 10.1073/pnas.94.16.8767.
- Wang X, McNiff J, Klump V, Asgari M, Gasparro F. An Unexpected Spectrum of p53 Mutations from Squamous Cell Carcinomas in Psoriasis Patients Treated with PUVA. Photochemistry And Photobiology 1997, 66: 294-299. PMID: 9277151, DOI: 10.1111/j.1751-1097.1997.tb08658.x.
- Sultan P, Schechner J, McNiff J, Hochman P, Hughes C, Lorber M, Askenase P, Pober J. Blockade of CD2-LFA-3 interactions protects human skin allografts in immunodeficient mouse/human chimeras. Nature Biotechnology 1997, 15: 759-762. PMID: 9255790, DOI: 10.1038/nbt0897-759.
- Huether MJ, Bbolognia J, Imaeda S, McNiff JM. Bullous pemphigoid associated with eosinophilic pustules. British Journal Of Dermatology 1997, 136: 641-642. PMID: 9155985, DOI: 10.1111/j.1365-2133.1997.tb02172.x.
- McNiff J, Cooper D, Howe G, Crotty P, Tallini G, Crouch J, Eisen R. Lymphomatoid granulomatosis of the skin and lung. An angiocentric T-cell-rich B-cell lymphoproliferative disorder. JAMA Dermatology 1996, 132: 1464-70. PMID: 8961876, DOI: 10.1001/archderm.132.12.1464.
- McNiff J, Cooper D, Howe G, Crotty P, Tallini G, Crouch J, Eisen R. Lymphomatoid Granulomatosis of the Skin and Lung: An Angiocentric T-Cell-Rich B-Cell Lymphoproliferative Disorder. JAMA Dermatology 1996, 132: 1464-1470. DOI: 10.1001/archderm.1996.03890360054010.