- Yale Clinical NeurophysiologyYale New Haven Hospital20 York StreetNew Haven, CT 06510
- Yale NeurologyYale Physicians Building800 Howard Avenue, Ste Lower LevelNew Haven, CT 06519
Hal Blumenfeld, MD, PhD
Biography
Hal Blumenfeld, MD, PhD, is a neurologist at Yale Medicine specializing in epilepsy. He is also the director of the Clinical Neuroscience Imaging Center at Yale School of Medicine.
Dr. Blumenfeld’s interest in the brain and consciousness began in college, where he majored in philosophy. He then studied medicine at Columbia University and completed his neurology residency at Massachusetts General Hospital. He arrived at Yale University in 1996 for his fellowship, where he was mentored by neurologists Susan and Dennis Spencer and has remained on the faculty ever since.
As a physician, Dr. Blumenfeld has a lot of empathy for his patients. “I think that one of the most important things about medicine is really trying to understand things from the patient’s viewpoint and to really care about what our patients are feeling,” he says.
Epilepsy patients in particular face unique challenges because their seizures are unpredictable and can have a severe impact on their lives. These episodes can be frightening, and Dr. Blumenfeld views his role of a physician as one who gives people back a sense of control by reducing seizures and minimizing treatment side effects.
To that end, Dr. Blumenfeld’s focus when working with patients is on developing the right treatment plan. He understands that each patient is unique and will react differently to medications and procedures.
In addition to seeing patients, Dr. Blumenfeld conducts research on treatments to restore consciousness during and after seizures for epilepsy patients. He is also the Mark Loughridge and Michele Williams Professor of Neurology, Professor of Neuroscience and of Neurosurgery at the Yale School of Medicine.
Titles
- Mark Loughridge and Michele Williams Professor of Neurology and Professor of Neuroscience and of Neurosurgery
- Director, Yale Clinical Neuroscience Imaging Center (CNIC)
Education & Training
- Associate Research ScientistYale School of Medicine (2000)
- FellowYale School of Medicine (1998)
- ResidentMassachusetts General Hospital (1996)
- PhDColumbia University (1992)
- MDColumbia University (1990)
Languages Spoken
- English
- עברית (Hebrew)
- Español (Spanish)
Additional Information
- Research Recognition Award, Clinical Science, American Epilepsy Society: (2017)
- Javits Neuroscience Investigator Award, National Institute of Neurological Disorders and Stroke: (2017)
- Graduate Mentor Award: (2015)
- The Francis Gilman Blake Award, Yale University, School of Medicine: (2007)
- John N. Whitaker Visiting Professorship, American Neurological Association: (2005)
- Dreifuss-Penry Epilepsy Research Award, American Academy of Neurology: (2005)
- AB of Psychiatry & Neurology, Epilepsy (2017)
- AB of Psychiatry & Neurology, Neurology (1998, recertified: 2018)
- Khan W, Chopra S, Zheng X, Liu S, Paszkowski P, Valcarce-Aspegren M, Sieu L, Mcgill S, Mccafferty C, Blumenfeld H. Neuronal rhythmicity and cortical arousal in a mouse model of absence epilepsy. Experimental Neurology 2024, 381: 114925. PMID: 39151596, DOI: 10.1016/j.expneurol.2024.114925.
- Schaper F, Nordberg J, Cohen A, Lin C, Hsu J, Horn A, Ferguson M, Siddiqi S, Drew W, Soussand L, Winkler A, Simó M, Bruna J, Rheims S, Guenot M, Bucci M, Nummenmaa L, Staals J, Colon A, Ackermans L, Bubrick E, Peters J, Wu O, Rost N, Grafman J, Blumenfeld H, Temel Y, Rouhl R, Joutsa J, Fox M. Mapping Lesion-Related Epilepsy to a Human Brain Network. JAMA Neurology 2023, 80: 891-902. PMID: 37399040, PMCID: PMC10318550, DOI: 10.1001/jamaneurol.2023.1988.
- Valencia I, Alexander A, Andrade D, Arevalo-Astrada M, Rubiños C, Auer N, Bainbridge J, Baxendale S, Bartolomei F, Becker D, Berg A, Bernasconi A, Bernasconi N, Bernhardt B, Bhatnagar S, Blümcke I, Blumenfeld H, Buchanan G, Burdette D, Burneo J, Busch R, Chauvel P, Chin J, Clifford L, Conner K, Cook M, Conway J, Diaz-Arastia R, Drees C, French J, Ganguly T, Gelfand M, Glauser T, Gleichgerrcht E, Goldman A, Gonzalez-Martinez J, Gotman J, Grinspan Z, Guilfoyle S, Gupta G, Hammer M, Hartman A, Hentges K, Hogan R, Huh L, Hyslop A, Jobst B, Josephson C, Kelley S, Knupp K, Koepp M, Kothare S, Krook-Magnuson E, Kwasa J, La Vega-Talbott M, Lam A, Lee J, Lowenstein D, Maturu S, Mayor L, McDonald C, McKee H, McKhann G, Meador K, Mefford H, Michael E, Mikati M, Millichap J, Mitchell J, Myers L, Naritoku D, Neville K, Noebels J, O’Brien T, Oluigbo C, Patel A, Pavlova M, T. Paz J, Pennell P, Perry M, Perucca P, Pitkänen A, Plueger M, Pugh M, Quigg M, Reddy S, Ryan C, Reynolds T, Sajatovic M, Santana-Gomez C, Schommer L, Schuele S, Shellhaas R, Shrey D, Singh R, Sperling M, Suleman S, Templer J, Thom M, Trinka E, Varadkar S, Velez-Ruiz N, Velíšková J, Voskobiynyk Y, Wagner J, Wagnon J, Waller C, Waller J, Wang Z, Welborn M, Wirrell E, Jobst B. Highlights From the Annual Meeting of the American Epilepsy Society 2022. Epilepsy Currents 2023 DOI: 10.1177/15357597231187227.
- Krestel H, Schreier D, Sakiri E, von Allmen A, Abukhadra Y, Nirkko A, Steinlin M, Rosenow F, Markhus R, Schneider G, Jagella C, Mathis J, Blumenfeld H. Predictive Power of Interictal Epileptiform Discharges in Fitness-to-Drive Evaluation. Neurology 2023, 101: e866-e878. PMID: 37414567, PMCID: PMC10501101, DOI: 10.1212/wnl.0000000000207531.
- James S, Sanggaard S, Akif A, Mishra S, Sanganahalli B, Blumenfeld H, Verhagen J, Hyder F, Herman P. Spatiotemporal features of neurovascular (un)coupling with stimulus-induced activity and hypercapnia challenge in cerebral cortex and olfactory bulb. Cerebrovascular And Brain Metabolism Reviews 2023, 43: 1891-1904. PMID: 37340791, PMCID: PMC10676132, DOI: 10.1177/0271678x231183887.
- Schaper F, Nordberg J, Cohen A, Lin C, Hsu J, Horn A, Ferguson M, Siddiqi S, Drew W, Soussand L, Winkler A, Simo M, Bruna J, Rheims S, Guenot M, Bucci M, Nummenmaa L, Staals J, Colon A, Ackermans L, Bubrick E, Peters J, Wu O, Rost N, Grafman J, Blumenfeld H, Temel Y, Rouhl R, Joutsa J, Fox M. Lesion-related epilepsy maps to a common brain network (P2-1.003). Neurology 2023, 100 DOI: 10.1212/wnl.0000000000203957.
- McCafferty C, Gruenbaum B, Tung R, Li J, Zheng X, Salvino P, Vincent P, Kratochvil Z, Ryu J, Khalaf A, Swift K, Akbari R, Islam W, Antwi P, Johnson E, Vitkovskiy P, Sampognaro J, Freedman I, Kundishora A, Depaulis A, David F, Crunelli V, Sanganahalli B, Herman P, Hyder F, Blumenfeld H. Decreased but diverse activity of cortical and thalamic neurons in consciousness-impairing rodent absence seizures. Nature Communications 2023, 14: 117. PMID: 36627270, PMCID: PMC9832004, DOI: 10.1038/s41467-022-35535-4.
- Kronemer S, Aksen M, Ding J, Ryu J, Xin Q, Ding Z, Prince J, Kwon H, Khalaf A, Forman S, Jin D, Wang K, Chen K, Hu C, Agarwal A, Saberski E, Wafa S, Morgan O, Wu J, Christison-Lagay K, Hasulak N, Morrell M, Urban A, Todd Constable R, Pitts M, Mark Richardson R, Crowley M, Blumenfeld H. Human visual consciousness involves large scale cortical and subcortical networks independent of task report and eye movement activity. Nature Communications 2022, 13: 7342. PMID: 36446792, PMCID: PMC9707162, DOI: 10.1038/s41467-022-35117-4.
- Juan E, Górska U, Kozma C, Papantonatos C, Bugnon T, Denis C, Kremen V, Worrell G, Struck A, Bateman L, Merricks E, Blumenfeld H, Tononi G, Schevon C, Boly M. Distinct signatures of loss of consciousness in focal impaired awareness versus tonic-clonic seizures. Brain 2022, 146: 109-123. PMID: 36383415, PMCID: PMC10582624, DOI: 10.1093/brain/awac291.
- Chen Y, Li S, Ge W, Jing J, Chen HY, Doherty D, Herman A, Kaleem S, Ding K, Osman G, Swisher CB, Smith C, Maciel CB, Alkhachroum A, Lee JW, Dhakar MB, Gilmore EJ, Sivaraju A, Hirsch LJ, Omay SB, Blumenfeld H, Sheth KN, Struck AF, Edlow BL, Westover MB, Kim JA. Quantitative epileptiform burden and electroencephalography background features predict post-traumatic epilepsy. Journal Of Neurology Neurosurgery & Psychiatry 2022, 94: 245-249. PMID: 36241423, PMCID: PMC9931627, DOI: 10.1136/jnnp-2022-329542.
- Ramirez V, Litvinov B, Gunawardane NA, Zhao CW, Yotter C, Quraishi IH, Blumenfeld H. Evaluating consciousness and awareness during focal seizures: responsiveness testing versus recall testing. Epileptic Disorders 2022, 24: 899-905. PMID: 35904040, PMCID: PMC10042123, DOI: 10.1684/epd.2022.1472.
- Gusso MM, Christison-Lagay KL, Zuckerman D, Chandrasekaran G, Kronemer SI, Ding JZ, Freedman NC, Nohama P, Blumenfeld H. More than a feeling: Scalp EEG and eye signals in conscious tactile perception. Consciousness And Cognition 2022, 105: 103411. PMID: 36156359, DOI: 10.1016/j.concog.2022.103411.
- Springer M, Khalaf A, Vincent P, Ryu JH, Abukhadra Y, Beniczky S, Glauser T, Krestel H, Blumenfeld H. A machine‐learning approach for predicting impaired consciousness in absence epilepsy. Annals Of Clinical And Translational Neurology 2022, 9: 1538-1550. PMID: 36114696, PMCID: PMC9539371, DOI: 10.1002/acn3.51647.
- Beniczky S, Tatum WO, Blumenfeld H, Stefan H, Mani J, Maillard L, Fahoum F, Vinayan KP, Mayor LC, Vlachou M, Seeck M, Ryvlin P, Kahane P. Seizure semiology: ILAE glossary of terms and their significance. Epileptic Disorders 2022, 24: 447-495. PMID: 35770761, DOI: 10.1684/epd.2022.1430.
- Sanganahalli BG, Thompson GJ, Parent M, Verhagen JV, Blumenfeld H, Herman P, Hyder F. Thalamic activations in rat brain by fMRI during tactile (forepaw, whisker) and non-tactile (visual, olfactory) sensory stimulations. PLOS ONE 2022, 17: e0267916. PMID: 35522646, PMCID: PMC9075615, DOI: 10.1371/journal.pone.0267916.
- Sivaraju A, Hirsch L, Gaspard N, Farooque P, Gerrard J, Xu Y, Deng Y, Damisah E, Blumenfeld H, Spencer DD. Factors Predicting Outcome After Intracranial EEG Evaluation in Patients With Medically Refractory Epilepsy. Neurology 2022, 99: e1-e10. PMID: 35508395, PMCID: PMC9259091, DOI: 10.1212/wnl.0000000000200569.
- Gummadavelli A, Sanganahalli B, Herman P, Hyder F, Blumenfeld H. EEG–fMRI in Animal Models. 2022, 663-694. DOI: 10.1007/978-3-031-07121-8_27.
- Schaper F, Nordberg J, Cohen A, Hsu J, Lin C, Ferguson M, Siddiqi S, Blumenfeld H, Joutsa J, Fox M. An epilepsy network derived from human brain lesions and deep brain stimulation. Brain Stimulation 2021, 14: 1643-1644. DOI: 10.1016/j.brs.2021.10.178.
- Xu J, Galardi MM, Pok B, Patel KK, Zhao CW, Andrews JP, Singla S, McCafferty CP, Feng L, Musonza ET, Kundishora AJ, Gummadavelli A, Gerrard JL, Laubach M, Schiff ND, Blumenfeld H. Thalamic Stimulation Improves Postictal Cortical Arousal and Behavior. Journal Of Neuroscience 2020, 40: 7343-7354. PMID: 32826310, PMCID: PMC7534908, DOI: 10.1523/jneurosci.1370-20.2020.
- Yue Z, Freedman IG, Vincent P, Andrews JP, Micek C, Aksen M, Martin R, Zuckerman D, Perrenoud Q, Neske GT, Sieu LA, Bo X, Cardin JA, Blumenfeld H. Up and Down States of Cortical Neurons in Focal Limbic Seizures. Cerebral Cortex 2019, 30: 3074-3086. PMID: 31800015, PMCID: PMC7197089, DOI: 10.1093/cercor/bhz295.
- Cohen E, Antwi P, Banz BC, Vincent P, Saha R, Arencibia CA, Ryu JH, Atac E, Saleem N, Tomatsu S, Swift K, Hu C, Krestel H, Farooque P, Levy S, Wu J, Crowley M, Vaca FE, Blumenfeld H. Realistic driving simulation during generalized epileptiform discharges to identify electroencephalographic features related to motor vehicle safety: Feasibility and pilot study. Epilepsia 2019, 61: 19-28. PMID: 31646628, PMCID: PMC7424790, DOI: 10.1111/epi.16356.
- Mishra A, Blumenfeld H. Prevention of Epileptogenesis in Animal Models. 2019, 135-147. DOI: 10.1017/9781316257951.014.
- Herman WX, Smith RE, Kronemer SI, Watsky RE, Chen WC, Gober LM, Touloumes GJ, Khosla M, Raja A, Horien CL, Morse EC, Botta KL, Hirsch LJ, Alkawadri R, Gerrard JL, Spencer DD, Blumenfeld H. A Switch and Wave of Neuronal Activity in the Cerebral Cortex During the First Second of Conscious Perception. Cerebral Cortex 2017, 29: 461-474. PMID: 29194517, PMCID: PMC6319177, DOI: 10.1093/cercor/bhx327.
- Englot D, Blumenfeld H. Functional MRI in Basic Epilepsy Research☆. 2017 DOI: 10.1016/b978-0-12-809324-5.00092-4.
- Guo JN, Kim R, Chen Y, Negishi M, Jhun S, Weiss S, Ryu JH, Bai X, Xiao W, Feeney E, Rodriguez-Fernandez J, Mistry H, Crunelli V, Crowley MJ, Mayes LC, Constable RT, Blumenfeld H. Impaired consciousness in patients with absence seizures investigated by functional MRI, EEG, and behavioural measures: a cross-sectional study. The Lancet Neurology 2016, 15: 1336-1345. PMID: 27839650, PMCID: PMC5504428, DOI: 10.1016/s1474-4422(16)30295-2.
- Morawo A, Pereira S, Pisani M, Blumenfeld H, Hirsch L, Sheth K, Gilmore E. Understanding the Pathophysiology of Brain Failure in Sepsis using EEG and NIRS (P1.312). Neurology 2016, 86 DOI: 10.1212/wnl.86.16_supplement.p1.312.
- Kundishora AJ, Gummadavelli A, Ma C, Liu M, McCafferty C, Schiff ND, Willie JT, Gross RE, Gerrard J, Blumenfeld H. Restoring Conscious Arousal During Focal Limbic Seizures with Deep Brain Stimulation. Cerebral Cortex 2016, 27: 1964-1975. PMID: 26941379, PMCID: PMC5964488, DOI: 10.1093/cercor/bhw035.
- Blumenfeld H. Chapter 16 Epilepsy and Consciousness. 2016, 255-270. DOI: 10.1016/b978-0-12-800948-2.00016-9.
- Blumenfeld H. Chapter 1 Neuroanatomical Basis of Consciousness. 2016, 3-29. DOI: 10.1016/b978-0-12-800948-2.00001-7.
- Motelow JE, Li W, Zhan Q, Mishra AM, Sachdev RN, Liu G, Gummadavelli A, Zayyad Z, Lee HS, Chu V, Andrews JP, Englot DJ, Herman P, Sanganahalli BG, Hyder F, Blumenfeld H. Decreased Subcortical Cholinergic Arousal in Focal Seizures. Neuron 2015, 85: 561-572. PMID: 25654258, PMCID: PMC4319118, DOI: 10.1016/j.neuron.2014.12.058.
- Kim R, Hyder F, Blumenfeld H. Physiological Basis of BOLD fMRI Decreases. Neuromethods 2014, 88: 221-236. DOI: 10.1007/978-1-4939-0724-3_11.
- Faingold C, Blumenfeld H. Chapter 1 Introduction to Neuronal Networks of the Brain. 2014, 1-10. DOI: 10.1016/b978-0-12-415804-7.00001-0.
- Faingold C, Blumenfeld H. Dedications. 2014, i. DOI: 10.1016/b978-0-12-415804-7.03001-x.
- Motelow J, Blumenfeld H. Chapter 21 Consciousness and Subcortical Arousal Systems. 2014, 277-298. DOI: 10.1016/b978-0-12-415804-7.00021-6.
- Guo J, Blumenfeld H. Chapter 6 Network Imaging. 2014, 77-89. DOI: 10.1016/b978-0-12-415804-7.00006-x.
- Faingold C, Blumenfeld H. Chapter 33 Future Trends in Neuronal Networks—Selective and Combined Targeting of Network Hubs. 2014, 467-485. DOI: 10.1016/b978-0-12-415804-7.00033-2.
- Furman M, Blumenfeld H. Temporal Lobe Seizures. 2013, 51-62. DOI: 10.1007/978-3-642-37580-4_4.
- Blumenfeld H. Impaired consciousness in epilepsy. The Lancet Neurology 2012, 11: 814-826. PMID: 22898735, PMCID: PMC3732214, DOI: 10.1016/s1474-4422(12)70188-6.
- Mishra AM, Ellens DJ, Schridde U, Motelow JE, Purcaro MJ, DeSalvo MN, Enev M, Sanganahalli BG, Hyder F, Blumenfeld H. Where fMRI and Electrophysiology Agree to Disagree: Corticothalamic and Striatal Activity Patterns in the WAG/Rij Rat. Journal Of Neuroscience 2011, 31: 15053-15064. PMID: 22016539, PMCID: PMC3432284, DOI: 10.1523/jneurosci.0101-11.2011.
- Danielson N, Guo J, Blumenfeld H. The Default Mode Network and Altered Consciousness in Epilepsy. Behavioural Neurology 2011, 24: 55-65. DOI: 10.1155/2011/912720.
- Englot DJ, Yang L, Hamid H, Danielson N, Bai X, Marfeo A, Yu L, Gordon A, Purcaro MJ, Motelow JE, Agarwal R, Ellens DJ, Golomb JD, Shamy MC, Zhang H, Carlson C, Doyle W, Devinsky O, Vives K, Spencer DD, Spencer SS, Schevon C, Zaveri HP, Blumenfeld H. Impaired consciousness in temporal lobe seizures: role of cortical slow activity. Brain 2010, 133: 3764-3777. PMID: 21081551, PMCID: PMC2995886, DOI: 10.1093/brain/awq316.
- Bai X, Vestal M, Berman R, Negishi M, Spann M, Vega C, Desalvo M, Novotny EJ, Constable RT, Blumenfeld H. Dynamic Time Course of Typical Childhood Absence Seizures: EEG, Behavior, and Functional Magnetic Resonance Imaging. Journal Of Neuroscience 2010, 30: 5884-5893. PMID: 20427649, PMCID: PMC2946206, DOI: 10.1523/jneurosci.5101-09.2010.
- Vestal M, Blumenfeld H. Pathophysiology of Absence Seizures. 2010, 225-234. DOI: 10.1007/978-1-84882-128-6_30.
- Ellens D, Blumenfeld H. EEG–fMRI in Animal Models. 2009, 485-509. DOI: 10.1007/978-3-540-87919-0_24.
- Blumenfeld H. A Clinical Guide to Epileptic Syndromes and their Treatment, second ed., C.P. Panayiotopoulos, Springer, New York, 2007. 578 pp, US$90, Hard cover and colored. ISBN: 978-1-84628-643-8. Epilepsy & Behavior 2009, 15: 263. DOI: 10.1016/j.yebeh.2009.03.023.
- Peng K, Blumenfeld H. Brain imaging and electroconvulsive therapy. 2009, 94-108. DOI: 10.1017/cbo9780511576393.006.
- Blumenfeld H. CHAPTER 2 The Neurological Examination of Consciousness. 2009, 15-30. DOI: 10.1016/b978-0-12-374168-4.00002-2.
- Englot D, Blumenfeld H. IMAGING | Functional MRI in Basic Epilepsy Research. 2009, 539-544. DOI: 10.1016/b978-012373961-2.00023-0.
- Purcaro M, Blumenfeld H. IMAGING | SPECT in Epilepsy Research. 2009, 558-564. DOI: 10.1016/b978-012373961-2.00024-2.
- Blumenfeld H. CHAPTER 19 Epilepsy and Consciousness. 2009, 247-260. DOI: 10.1016/b978-0-12-374168-4.00019-8.
- Ransom C, Blumenfeld H. 23 Acquired Epilepsy: Cellular and Molecular Mechanisms. 2007, 347-370. DOI: 10.1016/b978-012369509-3.50025-1.
- Berkovic S, Bilguvar K, Blackstone C, Bloch M, Blumenfeld H, Bredesen D, Bressman S, Brucal M, Burton E, Dalmau J, Dawson T, Dawson V, Depondt C, DiLuna M, DiMauro S, Ferrari M, Fink D, Flügel A, Frants R, Glorioso J, Goadsby P, Goldin A, Gunel M, Harel N, Helbig I, Hemmen T, Hisama F, Hyman B, Ingelsson M, Johnson D, Kamholz J, Kaul M, Kocsis J, Lammers G, Leckman J, Li J, Lipton S, Maragakis N, Mehlen P, Morimoto R, Orton K, Overeem S, Ozelius L, Pandolfo M, Pascual J, Paulson H, Peroutka S, Petroff O, Ransom C, Rao R, Rismanchi N, Rothstein J, Savitt J, Scheffer I, Schon E, Shy M, Strittmatter S, Tafti M, Tanriover G, Todi S, van den Maagdenberg A, Vance J, Vincent A, Voisine C, Waxman S, Wekerle H, Williams A, Wood J, Yang Y, Zivin J. Contributor's List. 2007, vii-ix. DOI: 10.1016/b978-012369509-3.50001-9.
- Novotny E, Scharff E, Zaveri H, Papademetris X, Blumenfeld H, Duckrow R, Hetherington H, Spencer S, Spencer D, Duncan J. CORRELATION OF MAGNETIC RESONANCE SPECTROSCOPIC IMAGING AND INTRACRANIAL EEG LOCALIZATION OF SEIZURES. Neuropediatrics 2006, 37 DOI: 10.1055/s-2006-945791.
- Blumenfeld H, Nersesyan H, Khubchandani M, Schridde U, Berman R, Rothman D, Hyder F. High resolution measurements of neuronal activity, cerebral blood flow, and fMRI during spike-wave seizures in WAG/Rij rats. Cerebrovascular And Brain Metabolism Reviews 2005, 25: s409-s409. DOI: 10.1038/sj.jcbfm.9591524.0409.
- Maandag N, Smith A, Blumenfeld H, Shulman R, Hyder F. Neural basis of localized and delocalized fMRI patterns. Cerebrovascular And Brain Metabolism Reviews 2005, 25: s383-s383. DOI: 10.1038/sj.jcbfm.9591524.0383.
- Hope O, Blumenfeld H. Cellular Physiology of Status Epilepticus. Current Clinical Neurology 2005, 159-180. DOI: 10.1385/1-59259-945-1:159.
- Hyder F, Blumenfeld H. Relationship between CMRO2 and Neuronal Activity. 2004, 173-194. DOI: 10.1002/0470020520.ch10.
- Hyder F, Kida I, Smith A, Blumenfeld H, Shulman R, Rothman D. Quantitative fMRI of rat brain by multi-modal MRI and MRS measurements. International Congress Series 2002, 1235: 57-71. DOI: 10.1016/s0531-5131(02)00173-5.
- Blumenfeld H, McCormick D. Corticothalamic Inputs Control the Pattern of Activity Generated in Thalamocortical Networks. Journal Of Neuroscience 2000, 20: 5153-5162. PMID: 10864972, PMCID: PMC6772273, DOI: 10.1523/jneurosci.20-13-05153.2000.
- Blumenfeld H, Spiral M, Kandel E, Siegelbaum S. Facilitatory and inhibitory transmitters modulate calcium influx during action potentials in Aplysia sensory neurons. Neuron 1990, 5: 487-499. PMID: 1976321, DOI: 10.1016/0896-6273(90)90088-w.
- Yale Clinical NeurophysiologyYale New Haven Hospital20 York StreetNew Haven, CT 06510
- Yale NeurologyYale Physicians Building800 Howard Avenue, Ste Lower LevelNew Haven, CT 06519
Biography
Hal Blumenfeld, MD, PhD, is a neurologist at Yale Medicine specializing in epilepsy. He is also the director of the Clinical Neuroscience Imaging Center at Yale School of Medicine.
Dr. Blumenfeld’s interest in the brain and consciousness began in college, where he majored in philosophy. He then studied medicine at Columbia University and completed his neurology residency at Massachusetts General Hospital. He arrived at Yale University in 1996 for his fellowship, where he was mentored by neurologists Susan and Dennis Spencer and has remained on the faculty ever since.
As a physician, Dr. Blumenfeld has a lot of empathy for his patients. “I think that one of the most important things about medicine is really trying to understand things from the patient’s viewpoint and to really care about what our patients are feeling,” he says.
Epilepsy patients in particular face unique challenges because their seizures are unpredictable and can have a severe impact on their lives. These episodes can be frightening, and Dr. Blumenfeld views his role of a physician as one who gives people back a sense of control by reducing seizures and minimizing treatment side effects.
To that end, Dr. Blumenfeld’s focus when working with patients is on developing the right treatment plan. He understands that each patient is unique and will react differently to medications and procedures.
In addition to seeing patients, Dr. Blumenfeld conducts research on treatments to restore consciousness during and after seizures for epilepsy patients. He is also the Mark Loughridge and Michele Williams Professor of Neurology, Professor of Neuroscience and of Neurosurgery at the Yale School of Medicine.
Titles
- Mark Loughridge and Michele Williams Professor of Neurology and Professor of Neuroscience and of Neurosurgery
- Director, Yale Clinical Neuroscience Imaging Center (CNIC)
Education & Training
- Associate Research ScientistYale School of Medicine (2000)
- FellowYale School of Medicine (1998)
- ResidentMassachusetts General Hospital (1996)
- PhDColumbia University (1992)
- MDColumbia University (1990)
Languages Spoken
- English
- עברית (Hebrew)
- Español (Spanish)
Additional Information
- Research Recognition Award, Clinical Science, American Epilepsy Society: (2017)
- Javits Neuroscience Investigator Award, National Institute of Neurological Disorders and Stroke: (2017)
- Graduate Mentor Award: (2015)
- The Francis Gilman Blake Award, Yale University, School of Medicine: (2007)
- John N. Whitaker Visiting Professorship, American Neurological Association: (2005)
- Dreifuss-Penry Epilepsy Research Award, American Academy of Neurology: (2005)
- AB of Psychiatry & Neurology, Epilepsy (2017)
- AB of Psychiatry & Neurology, Neurology (1998, recertified: 2018)
- Khan W, Chopra S, Zheng X, Liu S, Paszkowski P, Valcarce-Aspegren M, Sieu L, Mcgill S, Mccafferty C, Blumenfeld H. Neuronal rhythmicity and cortical arousal in a mouse model of absence epilepsy. Experimental Neurology 2024, 381: 114925. PMID: 39151596, DOI: 10.1016/j.expneurol.2024.114925.
- Schaper F, Nordberg J, Cohen A, Lin C, Hsu J, Horn A, Ferguson M, Siddiqi S, Drew W, Soussand L, Winkler A, Simó M, Bruna J, Rheims S, Guenot M, Bucci M, Nummenmaa L, Staals J, Colon A, Ackermans L, Bubrick E, Peters J, Wu O, Rost N, Grafman J, Blumenfeld H, Temel Y, Rouhl R, Joutsa J, Fox M. Mapping Lesion-Related Epilepsy to a Human Brain Network. JAMA Neurology 2023, 80: 891-902. PMID: 37399040, PMCID: PMC10318550, DOI: 10.1001/jamaneurol.2023.1988.
- Valencia I, Alexander A, Andrade D, Arevalo-Astrada M, Rubiños C, Auer N, Bainbridge J, Baxendale S, Bartolomei F, Becker D, Berg A, Bernasconi A, Bernasconi N, Bernhardt B, Bhatnagar S, Blümcke I, Blumenfeld H, Buchanan G, Burdette D, Burneo J, Busch R, Chauvel P, Chin J, Clifford L, Conner K, Cook M, Conway J, Diaz-Arastia R, Drees C, French J, Ganguly T, Gelfand M, Glauser T, Gleichgerrcht E, Goldman A, Gonzalez-Martinez J, Gotman J, Grinspan Z, Guilfoyle S, Gupta G, Hammer M, Hartman A, Hentges K, Hogan R, Huh L, Hyslop A, Jobst B, Josephson C, Kelley S, Knupp K, Koepp M, Kothare S, Krook-Magnuson E, Kwasa J, La Vega-Talbott M, Lam A, Lee J, Lowenstein D, Maturu S, Mayor L, McDonald C, McKee H, McKhann G, Meador K, Mefford H, Michael E, Mikati M, Millichap J, Mitchell J, Myers L, Naritoku D, Neville K, Noebels J, O’Brien T, Oluigbo C, Patel A, Pavlova M, T. Paz J, Pennell P, Perry M, Perucca P, Pitkänen A, Plueger M, Pugh M, Quigg M, Reddy S, Ryan C, Reynolds T, Sajatovic M, Santana-Gomez C, Schommer L, Schuele S, Shellhaas R, Shrey D, Singh R, Sperling M, Suleman S, Templer J, Thom M, Trinka E, Varadkar S, Velez-Ruiz N, Velíšková J, Voskobiynyk Y, Wagner J, Wagnon J, Waller C, Waller J, Wang Z, Welborn M, Wirrell E, Jobst B. Highlights From the Annual Meeting of the American Epilepsy Society 2022. Epilepsy Currents 2023 DOI: 10.1177/15357597231187227.
- Krestel H, Schreier D, Sakiri E, von Allmen A, Abukhadra Y, Nirkko A, Steinlin M, Rosenow F, Markhus R, Schneider G, Jagella C, Mathis J, Blumenfeld H. Predictive Power of Interictal Epileptiform Discharges in Fitness-to-Drive Evaluation. Neurology 2023, 101: e866-e878. PMID: 37414567, PMCID: PMC10501101, DOI: 10.1212/wnl.0000000000207531.
- James S, Sanggaard S, Akif A, Mishra S, Sanganahalli B, Blumenfeld H, Verhagen J, Hyder F, Herman P. Spatiotemporal features of neurovascular (un)coupling with stimulus-induced activity and hypercapnia challenge in cerebral cortex and olfactory bulb. Cerebrovascular And Brain Metabolism Reviews 2023, 43: 1891-1904. PMID: 37340791, PMCID: PMC10676132, DOI: 10.1177/0271678x231183887.
- Schaper F, Nordberg J, Cohen A, Lin C, Hsu J, Horn A, Ferguson M, Siddiqi S, Drew W, Soussand L, Winkler A, Simo M, Bruna J, Rheims S, Guenot M, Bucci M, Nummenmaa L, Staals J, Colon A, Ackermans L, Bubrick E, Peters J, Wu O, Rost N, Grafman J, Blumenfeld H, Temel Y, Rouhl R, Joutsa J, Fox M. Lesion-related epilepsy maps to a common brain network (P2-1.003). Neurology 2023, 100 DOI: 10.1212/wnl.0000000000203957.
- McCafferty C, Gruenbaum B, Tung R, Li J, Zheng X, Salvino P, Vincent P, Kratochvil Z, Ryu J, Khalaf A, Swift K, Akbari R, Islam W, Antwi P, Johnson E, Vitkovskiy P, Sampognaro J, Freedman I, Kundishora A, Depaulis A, David F, Crunelli V, Sanganahalli B, Herman P, Hyder F, Blumenfeld H. Decreased but diverse activity of cortical and thalamic neurons in consciousness-impairing rodent absence seizures. Nature Communications 2023, 14: 117. PMID: 36627270, PMCID: PMC9832004, DOI: 10.1038/s41467-022-35535-4.
- Kronemer S, Aksen M, Ding J, Ryu J, Xin Q, Ding Z, Prince J, Kwon H, Khalaf A, Forman S, Jin D, Wang K, Chen K, Hu C, Agarwal A, Saberski E, Wafa S, Morgan O, Wu J, Christison-Lagay K, Hasulak N, Morrell M, Urban A, Todd Constable R, Pitts M, Mark Richardson R, Crowley M, Blumenfeld H. Human visual consciousness involves large scale cortical and subcortical networks independent of task report and eye movement activity. Nature Communications 2022, 13: 7342. PMID: 36446792, PMCID: PMC9707162, DOI: 10.1038/s41467-022-35117-4.
- Juan E, Górska U, Kozma C, Papantonatos C, Bugnon T, Denis C, Kremen V, Worrell G, Struck A, Bateman L, Merricks E, Blumenfeld H, Tononi G, Schevon C, Boly M. Distinct signatures of loss of consciousness in focal impaired awareness versus tonic-clonic seizures. Brain 2022, 146: 109-123. PMID: 36383415, PMCID: PMC10582624, DOI: 10.1093/brain/awac291.
- Chen Y, Li S, Ge W, Jing J, Chen HY, Doherty D, Herman A, Kaleem S, Ding K, Osman G, Swisher CB, Smith C, Maciel CB, Alkhachroum A, Lee JW, Dhakar MB, Gilmore EJ, Sivaraju A, Hirsch LJ, Omay SB, Blumenfeld H, Sheth KN, Struck AF, Edlow BL, Westover MB, Kim JA. Quantitative epileptiform burden and electroencephalography background features predict post-traumatic epilepsy. Journal Of Neurology Neurosurgery & Psychiatry 2022, 94: 245-249. PMID: 36241423, PMCID: PMC9931627, DOI: 10.1136/jnnp-2022-329542.
- Ramirez V, Litvinov B, Gunawardane NA, Zhao CW, Yotter C, Quraishi IH, Blumenfeld H. Evaluating consciousness and awareness during focal seizures: responsiveness testing versus recall testing. Epileptic Disorders 2022, 24: 899-905. PMID: 35904040, PMCID: PMC10042123, DOI: 10.1684/epd.2022.1472.
- Gusso MM, Christison-Lagay KL, Zuckerman D, Chandrasekaran G, Kronemer SI, Ding JZ, Freedman NC, Nohama P, Blumenfeld H. More than a feeling: Scalp EEG and eye signals in conscious tactile perception. Consciousness And Cognition 2022, 105: 103411. PMID: 36156359, DOI: 10.1016/j.concog.2022.103411.
- Springer M, Khalaf A, Vincent P, Ryu JH, Abukhadra Y, Beniczky S, Glauser T, Krestel H, Blumenfeld H. A machine‐learning approach for predicting impaired consciousness in absence epilepsy. Annals Of Clinical And Translational Neurology 2022, 9: 1538-1550. PMID: 36114696, PMCID: PMC9539371, DOI: 10.1002/acn3.51647.
- Beniczky S, Tatum WO, Blumenfeld H, Stefan H, Mani J, Maillard L, Fahoum F, Vinayan KP, Mayor LC, Vlachou M, Seeck M, Ryvlin P, Kahane P. Seizure semiology: ILAE glossary of terms and their significance. Epileptic Disorders 2022, 24: 447-495. PMID: 35770761, DOI: 10.1684/epd.2022.1430.
- Sanganahalli BG, Thompson GJ, Parent M, Verhagen JV, Blumenfeld H, Herman P, Hyder F. Thalamic activations in rat brain by fMRI during tactile (forepaw, whisker) and non-tactile (visual, olfactory) sensory stimulations. PLOS ONE 2022, 17: e0267916. PMID: 35522646, PMCID: PMC9075615, DOI: 10.1371/journal.pone.0267916.
- Sivaraju A, Hirsch L, Gaspard N, Farooque P, Gerrard J, Xu Y, Deng Y, Damisah E, Blumenfeld H, Spencer DD. Factors Predicting Outcome After Intracranial EEG Evaluation in Patients With Medically Refractory Epilepsy. Neurology 2022, 99: e1-e10. PMID: 35508395, PMCID: PMC9259091, DOI: 10.1212/wnl.0000000000200569.
- Gummadavelli A, Sanganahalli B, Herman P, Hyder F, Blumenfeld H. EEG–fMRI in Animal Models. 2022, 663-694. DOI: 10.1007/978-3-031-07121-8_27.
- Schaper F, Nordberg J, Cohen A, Hsu J, Lin C, Ferguson M, Siddiqi S, Blumenfeld H, Joutsa J, Fox M. An epilepsy network derived from human brain lesions and deep brain stimulation. Brain Stimulation 2021, 14: 1643-1644. DOI: 10.1016/j.brs.2021.10.178.
- Xu J, Galardi MM, Pok B, Patel KK, Zhao CW, Andrews JP, Singla S, McCafferty CP, Feng L, Musonza ET, Kundishora AJ, Gummadavelli A, Gerrard JL, Laubach M, Schiff ND, Blumenfeld H. Thalamic Stimulation Improves Postictal Cortical Arousal and Behavior. Journal Of Neuroscience 2020, 40: 7343-7354. PMID: 32826310, PMCID: PMC7534908, DOI: 10.1523/jneurosci.1370-20.2020.
- Yue Z, Freedman IG, Vincent P, Andrews JP, Micek C, Aksen M, Martin R, Zuckerman D, Perrenoud Q, Neske GT, Sieu LA, Bo X, Cardin JA, Blumenfeld H. Up and Down States of Cortical Neurons in Focal Limbic Seizures. Cerebral Cortex 2019, 30: 3074-3086. PMID: 31800015, PMCID: PMC7197089, DOI: 10.1093/cercor/bhz295.
- Cohen E, Antwi P, Banz BC, Vincent P, Saha R, Arencibia CA, Ryu JH, Atac E, Saleem N, Tomatsu S, Swift K, Hu C, Krestel H, Farooque P, Levy S, Wu J, Crowley M, Vaca FE, Blumenfeld H. Realistic driving simulation during generalized epileptiform discharges to identify electroencephalographic features related to motor vehicle safety: Feasibility and pilot study. Epilepsia 2019, 61: 19-28. PMID: 31646628, PMCID: PMC7424790, DOI: 10.1111/epi.16356.
- Mishra A, Blumenfeld H. Prevention of Epileptogenesis in Animal Models. 2019, 135-147. DOI: 10.1017/9781316257951.014.
- Herman WX, Smith RE, Kronemer SI, Watsky RE, Chen WC, Gober LM, Touloumes GJ, Khosla M, Raja A, Horien CL, Morse EC, Botta KL, Hirsch LJ, Alkawadri R, Gerrard JL, Spencer DD, Blumenfeld H. A Switch and Wave of Neuronal Activity in the Cerebral Cortex During the First Second of Conscious Perception. Cerebral Cortex 2017, 29: 461-474. PMID: 29194517, PMCID: PMC6319177, DOI: 10.1093/cercor/bhx327.
- Englot D, Blumenfeld H. Functional MRI in Basic Epilepsy Research☆. 2017 DOI: 10.1016/b978-0-12-809324-5.00092-4.
- Guo JN, Kim R, Chen Y, Negishi M, Jhun S, Weiss S, Ryu JH, Bai X, Xiao W, Feeney E, Rodriguez-Fernandez J, Mistry H, Crunelli V, Crowley MJ, Mayes LC, Constable RT, Blumenfeld H. Impaired consciousness in patients with absence seizures investigated by functional MRI, EEG, and behavioural measures: a cross-sectional study. The Lancet Neurology 2016, 15: 1336-1345. PMID: 27839650, PMCID: PMC5504428, DOI: 10.1016/s1474-4422(16)30295-2.
- Morawo A, Pereira S, Pisani M, Blumenfeld H, Hirsch L, Sheth K, Gilmore E. Understanding the Pathophysiology of Brain Failure in Sepsis using EEG and NIRS (P1.312). Neurology 2016, 86 DOI: 10.1212/wnl.86.16_supplement.p1.312.
- Kundishora AJ, Gummadavelli A, Ma C, Liu M, McCafferty C, Schiff ND, Willie JT, Gross RE, Gerrard J, Blumenfeld H. Restoring Conscious Arousal During Focal Limbic Seizures with Deep Brain Stimulation. Cerebral Cortex 2016, 27: 1964-1975. PMID: 26941379, PMCID: PMC5964488, DOI: 10.1093/cercor/bhw035.
- Blumenfeld H. Chapter 16 Epilepsy and Consciousness. 2016, 255-270. DOI: 10.1016/b978-0-12-800948-2.00016-9.
- Blumenfeld H. Chapter 1 Neuroanatomical Basis of Consciousness. 2016, 3-29. DOI: 10.1016/b978-0-12-800948-2.00001-7.
- Motelow JE, Li W, Zhan Q, Mishra AM, Sachdev RN, Liu G, Gummadavelli A, Zayyad Z, Lee HS, Chu V, Andrews JP, Englot DJ, Herman P, Sanganahalli BG, Hyder F, Blumenfeld H. Decreased Subcortical Cholinergic Arousal in Focal Seizures. Neuron 2015, 85: 561-572. PMID: 25654258, PMCID: PMC4319118, DOI: 10.1016/j.neuron.2014.12.058.
- Kim R, Hyder F, Blumenfeld H. Physiological Basis of BOLD fMRI Decreases. Neuromethods 2014, 88: 221-236. DOI: 10.1007/978-1-4939-0724-3_11.
- Faingold C, Blumenfeld H. Chapter 1 Introduction to Neuronal Networks of the Brain. 2014, 1-10. DOI: 10.1016/b978-0-12-415804-7.00001-0.
- Faingold C, Blumenfeld H. Dedications. 2014, i. DOI: 10.1016/b978-0-12-415804-7.03001-x.
- Motelow J, Blumenfeld H. Chapter 21 Consciousness and Subcortical Arousal Systems. 2014, 277-298. DOI: 10.1016/b978-0-12-415804-7.00021-6.
- Guo J, Blumenfeld H. Chapter 6 Network Imaging. 2014, 77-89. DOI: 10.1016/b978-0-12-415804-7.00006-x.
- Faingold C, Blumenfeld H. Chapter 33 Future Trends in Neuronal Networks—Selective and Combined Targeting of Network Hubs. 2014, 467-485. DOI: 10.1016/b978-0-12-415804-7.00033-2.
- Furman M, Blumenfeld H. Temporal Lobe Seizures. 2013, 51-62. DOI: 10.1007/978-3-642-37580-4_4.
- Blumenfeld H. Impaired consciousness in epilepsy. The Lancet Neurology 2012, 11: 814-826. PMID: 22898735, PMCID: PMC3732214, DOI: 10.1016/s1474-4422(12)70188-6.
- Mishra AM, Ellens DJ, Schridde U, Motelow JE, Purcaro MJ, DeSalvo MN, Enev M, Sanganahalli BG, Hyder F, Blumenfeld H. Where fMRI and Electrophysiology Agree to Disagree: Corticothalamic and Striatal Activity Patterns in the WAG/Rij Rat. Journal Of Neuroscience 2011, 31: 15053-15064. PMID: 22016539, PMCID: PMC3432284, DOI: 10.1523/jneurosci.0101-11.2011.
- Danielson N, Guo J, Blumenfeld H. The Default Mode Network and Altered Consciousness in Epilepsy. Behavioural Neurology 2011, 24: 55-65. DOI: 10.1155/2011/912720.
- Englot DJ, Yang L, Hamid H, Danielson N, Bai X, Marfeo A, Yu L, Gordon A, Purcaro MJ, Motelow JE, Agarwal R, Ellens DJ, Golomb JD, Shamy MC, Zhang H, Carlson C, Doyle W, Devinsky O, Vives K, Spencer DD, Spencer SS, Schevon C, Zaveri HP, Blumenfeld H. Impaired consciousness in temporal lobe seizures: role of cortical slow activity. Brain 2010, 133: 3764-3777. PMID: 21081551, PMCID: PMC2995886, DOI: 10.1093/brain/awq316.
- Bai X, Vestal M, Berman R, Negishi M, Spann M, Vega C, Desalvo M, Novotny EJ, Constable RT, Blumenfeld H. Dynamic Time Course of Typical Childhood Absence Seizures: EEG, Behavior, and Functional Magnetic Resonance Imaging. Journal Of Neuroscience 2010, 30: 5884-5893. PMID: 20427649, PMCID: PMC2946206, DOI: 10.1523/jneurosci.5101-09.2010.
- Vestal M, Blumenfeld H. Pathophysiology of Absence Seizures. 2010, 225-234. DOI: 10.1007/978-1-84882-128-6_30.
- Ellens D, Blumenfeld H. EEG–fMRI in Animal Models. 2009, 485-509. DOI: 10.1007/978-3-540-87919-0_24.
- Blumenfeld H. A Clinical Guide to Epileptic Syndromes and their Treatment, second ed., C.P. Panayiotopoulos, Springer, New York, 2007. 578 pp, US$90, Hard cover and colored. ISBN: 978-1-84628-643-8. Epilepsy & Behavior 2009, 15: 263. DOI: 10.1016/j.yebeh.2009.03.023.
- Peng K, Blumenfeld H. Brain imaging and electroconvulsive therapy. 2009, 94-108. DOI: 10.1017/cbo9780511576393.006.
- Blumenfeld H. CHAPTER 2 The Neurological Examination of Consciousness. 2009, 15-30. DOI: 10.1016/b978-0-12-374168-4.00002-2.
- Englot D, Blumenfeld H. IMAGING | Functional MRI in Basic Epilepsy Research. 2009, 539-544. DOI: 10.1016/b978-012373961-2.00023-0.
- Purcaro M, Blumenfeld H. IMAGING | SPECT in Epilepsy Research. 2009, 558-564. DOI: 10.1016/b978-012373961-2.00024-2.
- Blumenfeld H. CHAPTER 19 Epilepsy and Consciousness. 2009, 247-260. DOI: 10.1016/b978-0-12-374168-4.00019-8.
- Ransom C, Blumenfeld H. 23 Acquired Epilepsy: Cellular and Molecular Mechanisms. 2007, 347-370. DOI: 10.1016/b978-012369509-3.50025-1.
- Berkovic S, Bilguvar K, Blackstone C, Bloch M, Blumenfeld H, Bredesen D, Bressman S, Brucal M, Burton E, Dalmau J, Dawson T, Dawson V, Depondt C, DiLuna M, DiMauro S, Ferrari M, Fink D, Flügel A, Frants R, Glorioso J, Goadsby P, Goldin A, Gunel M, Harel N, Helbig I, Hemmen T, Hisama F, Hyman B, Ingelsson M, Johnson D, Kamholz J, Kaul M, Kocsis J, Lammers G, Leckman J, Li J, Lipton S, Maragakis N, Mehlen P, Morimoto R, Orton K, Overeem S, Ozelius L, Pandolfo M, Pascual J, Paulson H, Peroutka S, Petroff O, Ransom C, Rao R, Rismanchi N, Rothstein J, Savitt J, Scheffer I, Schon E, Shy M, Strittmatter S, Tafti M, Tanriover G, Todi S, van den Maagdenberg A, Vance J, Vincent A, Voisine C, Waxman S, Wekerle H, Williams A, Wood J, Yang Y, Zivin J. Contributor's List. 2007, vii-ix. DOI: 10.1016/b978-012369509-3.50001-9.
- Novotny E, Scharff E, Zaveri H, Papademetris X, Blumenfeld H, Duckrow R, Hetherington H, Spencer S, Spencer D, Duncan J. CORRELATION OF MAGNETIC RESONANCE SPECTROSCOPIC IMAGING AND INTRACRANIAL EEG LOCALIZATION OF SEIZURES. Neuropediatrics 2006, 37 DOI: 10.1055/s-2006-945791.
- Blumenfeld H, Nersesyan H, Khubchandani M, Schridde U, Berman R, Rothman D, Hyder F. High resolution measurements of neuronal activity, cerebral blood flow, and fMRI during spike-wave seizures in WAG/Rij rats. Cerebrovascular And Brain Metabolism Reviews 2005, 25: s409-s409. DOI: 10.1038/sj.jcbfm.9591524.0409.
- Maandag N, Smith A, Blumenfeld H, Shulman R, Hyder F. Neural basis of localized and delocalized fMRI patterns. Cerebrovascular And Brain Metabolism Reviews 2005, 25: s383-s383. DOI: 10.1038/sj.jcbfm.9591524.0383.
- Hope O, Blumenfeld H. Cellular Physiology of Status Epilepticus. Current Clinical Neurology 2005, 159-180. DOI: 10.1385/1-59259-945-1:159.
- Hyder F, Blumenfeld H. Relationship between CMRO2 and Neuronal Activity. 2004, 173-194. DOI: 10.1002/0470020520.ch10.
- Hyder F, Kida I, Smith A, Blumenfeld H, Shulman R, Rothman D. Quantitative fMRI of rat brain by multi-modal MRI and MRS measurements. International Congress Series 2002, 1235: 57-71. DOI: 10.1016/s0531-5131(02)00173-5.
- Blumenfeld H, McCormick D. Corticothalamic Inputs Control the Pattern of Activity Generated in Thalamocortical Networks. Journal Of Neuroscience 2000, 20: 5153-5162. PMID: 10864972, PMCID: PMC6772273, DOI: 10.1523/jneurosci.20-13-05153.2000.
- Blumenfeld H, Spiral M, Kandel E, Siegelbaum S. Facilitatory and inhibitory transmitters modulate calcium influx during action potentials in Aplysia sensory neurons. Neuron 1990, 5: 487-499. PMID: 1976321, DOI: 10.1016/0896-6273(90)90088-w.
- Yale Clinical NeurophysiologyYale New Haven Hospital20 York StreetNew Haven, CT 06510
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- Yale Clinical NeurophysiologyYale New Haven Hospital20 York StreetNew Haven, CT 06510
- Yale NeurologyYale Physicians Building800 Howard Avenue, Ste Lower LevelNew Haven, CT 06519