- Yale Orthopaedics/Musculoskeletal OncologyYale Physicians Building800 Howard Avenue, Ste 1st floorNew Haven, CT 06519
Gary Friedlaender, MD, BS
Biography
Gary E. Friedlaender, MD, is an orthopaedic surgeon who specializes in musculoskeletal oncology, or benign and malignant tumors of the bones. He leads the Sarcoma Program at Smilow Cancer Hospital, treating rare cancers that involve the bones, cartilage, muscle and other tissues in the body.
Dr. Friedlaender has achieved national recognition for his surgical innovations, including development of limb-salvaging techniques that are now considered essential to orthopaedic oncology surgery.
However, he considers his close connections with his patients to be the key element in his approach to orthopaedics. Good physicians are great communicators—skilled at discovering information that patients may be reluctant to share, or that they have misinterpreted or forgotten, Dr. Friedlaender says. He tells new doctors, “In asking what is bothering the patient, we must convey our interest in hearing what they have to say. Sit down, make eye contact, ask open-ended questions, and, whatever you do, don’t interrupt.”
Dr. Friedlaender is a professor of orthopaedics and rehabilitation at Yale School of Medicine. He was chair of the department for 30 years, and was responsible for making Yale Orthopaedics & Rehabilitation a leader in the field. He has served as president of several important professional organizations, including the American Orthopaedic Association. Connecticut Magazine has included Dr. Friedlaender in its annual lists of Top Docs in the state.
He says he decided to enter the medical field when he was a child, after watching his father, also a physician, at work. He chose to pursue orthopaedics because he admired the doctors who treated the musculoskeletal injuries he had as a child. He has seen the field change dramatically since then. When he was a resident in the 1970s, the survival rate for osteosarcoma, the most common type of bone cancer, was 15 to 20 percent; now the cure rate is 80 percent.
“I get joy from working in an environment like Yale, and even more so now with Smilow Cancer Hospital,” Dr. Friedlaender says. “There are so many capable, creative and energetic physicians and they are all under one roof. The scientists, nursing staff, and support individuals make the work in oncology not only possible, but rewarding. It’s all about the patient.”
Titles
- Wayne O. Southwick Professor of Orthopaedics and Rehabilitation and Professor of Pathology
- Chair Emeritus, Department of Orthopaedics and Rehabilitation
Education & Training
- FellowMassachusetts General Hospital (1983)
- FellowBerg-Sloat Traveling Fellowship (Karolinska Inst,Oxford Univ,Univ Nottingham, Royal National Ortho), Sweden and England Bone Biology and Tumor Immunobiology (1976)
- ResidentYale-New Haven Hospital (1974)
- FellowNIH-Post-doctoral Research Fellowship, Yale University School of Medicine, New Haven, CT Oncology and Immunobiology (1973)
- ResidentUniversity of Michigan (1971)
- InternUniversity of Michigan Medical Center, Ann Arbor, Michigan Surgery (1970)
- MDUniversity of Michigan Medical School (1969)
- FellowFord Foundation Fellowship in Reproductive Biology, University of Michigan, Ann Arbor, Michigan Reproductive Immunobiology (1969)
- BSUniversity of Michigan, Zoology (1967)
Additional Information
- Tipton Leadership Award: American Academy of Orthopaedic Surgeons (2014)
- Distinguished Contributions to Orthopaedics: American Orthopaedic Association (2013)
- Inaugural Stefansky Visiting Professor for Communication Skills: University of Toronto (2012)
- Crawford J. Campbell Visiting Professor: Albany Medical Center (2012)
- Allen Fellowship Distinguished Visiting Professor: Case Western Reserve School of Medicine (2012)
- Alan DeForest Smith Lecturer: New York Orthopaedic Hospital/Columbia University (2011)
- President: American Orthopaedic Association (2010)
- Distinguished Achievement Award: University of Michigan Medical Alumni Association (2008)
- Edward T. Smith Visiting Professor: University of Texas (Houston) (2006)
- Fischer-Owen Lecturer: University of Louisville (2005)
- AB of Orthopaedic Surgery, Orthopaedic Surgery (1975)
- National Institutes of Health (2002 - 2003): NIH Consensus Development Conference On Total Knee Replacements Planning Committee
- American Academy of Orthopaedic Surgeons (2001 - 2002): Council of Subspecialty Societies
- National Institutes of Health (2001 - Present): Center for Scientific Review, Bone, Muscle, Connective Tissue Boundaries Study Section
- Orthopaedic Research and Education Foundation (2000 - 2005): Grant Peer Review Committee
- Journal of the American Academy of Orthopaedic Surgeons (2000 - Present): Editorial Review Board
- Journal Spine (2000 - Present): Board of Associate Editors
- National Institutes of Health (1998 - 2002): NIAMS Council
- Food and Drug Administration (1996 - 1997): FDA Panel on Blood and Blood Products
- Arthritis Association (1996 - 1997): Medical Advisory Board
- The Cancer Journal (1994 - 2007): Board of Associate Editors
- Friedlaender GE. CORR Insights®: Imposter Syndrome Among Surgeons is Associated With Intolerance of Uncertainty and Lower Confidence in Problem Solving. Clinical Orthopaedics And Related Research® 2022, 481: 672-674. PMID: 36166271, PMCID: PMC10013620, DOI: 10.1097/corr.0000000000002427.
- Friedlaender GE, Friedlaender LK. Reply to the Letter to the Editor: Art in Science: Quackery and Promises Not Kept. Clinical Orthopaedics And Related Research® 2022, 480: 2060-2060. PMID: 36001023, PMCID: PMC9473757, DOI: 10.1097/corr.0000000000002350.
- Friedlaender GE, Friedlaender LK. Art in Science: Quackery and Promises Not Kept. Clinical Orthopaedics And Related Research® 2022, 480: 1458-1460. PMID: 35767816, PMCID: PMC9278922, DOI: 10.1097/corr.0000000000002290.
- Friedlaender GE, Friedlaender LK. Art in Science: Alchemy As Seen Through The Eyes of David Teniers the Younger. Clinical Orthopaedics And Related Research® 2021, 480: 235-236. PMID: 34870955, PMCID: PMC8747614, DOI: 10.1097/corr.0000000000002069.
- Chan SM, Moran J, Friedlaender LK, Friedlaender GE. Art in Science: The Boxer at Rest. Clinical Orthopaedics And Related Research® 2021, 479: 1441-1443. PMID: 34106904, PMCID: PMC8208444, DOI: 10.1097/corr.0000000000001847.
- Flores M, Friedlaender LK, Friedlaender GE. Art in Science-Humility: As Portrayed by Pietro Lorenzetti. Clinical Orthopaedics And Related Research® 2021, 479: 458-460. PMID: 33543878, PMCID: PMC7899731, DOI: 10.1097/corr.0000000000001666.
- Chan SM, Friedlaender GE, Friedlaender LK. Art in Science-Goya to Dr. Arrieta: An Illustration of Patient-Physician Trust. Clinical Orthopaedics And Related Research® 2020, 478: 2221-2224. PMID: 32898044, PMCID: PMC7491894, DOI: 10.1097/corr.0000000000001470.
- Friedlaender GE, Friedlaender LK. Art in Science: Pieter Bruegel the Elder and the Plague. Clinical Orthopaedics And Related Research® 2020, 478: 1416-1418. PMID: 32574469, PMCID: PMC7310395, DOI: 10.1097/corr.0000000000001325.
- Jiang W, Latich I, Lindskog D, Friedlaender G, Lee F. Progression of Femoral Osteolytic Metastases after Intramedullary Nailing and Subsequent Salvage Techniques. Cancers 2024, 16: 2812. PMID: 39199585, PMCID: PMC11352437, DOI: 10.3390/cancers16162812.
- Jiang W, Caruana D, Dussik C, Conway D, Latich I, Chapiro J, Lindskog D, Friedlaender G, Lee F. Bone Mass Changes Following Percutaneous Radiofrequency Ablation, Osteoplasty, Reinforcement, and Internal Fixation of Periacetabular Osteolytic Metastases. Journal Of Clinical Medicine 2023, 12: 4613. PMID: 37510728, PMCID: PMC10380351, DOI: 10.3390/jcm12144613.
- Jiang W, Friedlaender G, Lindskog D, Latich I, Lee F. Comparison of Percutaneous Interventional Ablation-Osteoplasty-Reinforcement-Internal Fixation (AORIF), Long Intramedullary Nailing, and Hemiarthroplasty for the Treatment of Focal Metastatic Osteolytic Lesions in the Femoral Head and Neck. CardioVascular And Interventional Radiology 2023, 46: 649-657. PMID: 37052716, DOI: 10.1007/s00270-023-03425-x.
- Dussik C, Toombs C, Alder K, Yu K, Berson E, Ibe I, Li F, Lindskog D, Friedlaender G, Latich I, Lee F. Percutaneous Ablation, Osteoplasty, Reinforcement, and Internal Fixation for Pain and Ambulatory Function in Periacetabular Osteolytic Malignancies. Radiology 2023, 307: e221401. PMID: 36916888, DOI: 10.1148/radiol.221401.
- Pirkle S, Chen A, Samora J, Friedlaender G. What’s Important: Ortho, I Screwed Up. Journal Of Bone And Joint Surgery 2023, 105: 962-964. PMID: 36728460, DOI: 10.2106/jbjs.22.01214.
- Samuel AM, Munger AM, Lee FY, Friedlaender GE, Ibe IK, Lindskog DM. Bone Scans Have Little Utility in the Evaluation of Well-Differentiated Cartilaginous Lesions of the Humerus. Orthopedics 2020, 43: e498-e502. PMID: 32882054, DOI: 10.3928/01477447-20200827-05.
- Lee FY, Latich I, Toombs C, Mungur A, Conway D, Alder K, Ibe I, Lindskog D, Friedlaender G. Minimally Invasive Image-Guided Ablation, Osteoplasty, Reinforcement, and Internal Fixation (AORIF) for Osteolytic Lesions in the Pelvis and Periarticular Regions of Weight-Bearing Bones. Journal Of Vascular And Interventional Radiology 2020, 31: 649-658.e1. PMID: 32139256, DOI: 10.1016/j.jvir.2019.11.029.
- Miccio J, Jairam V, Gao S, Augustyn A, Oladeru O, Onderdonk B, Costa J, Han D, Khan S, Friedlaender G, Lindskog D, Deshpande H, Tara H, Osborn H, Roberts K, Patel K. Predictors of Lymph Node Involvement by Soft Tissue Sarcoma: An Analysis of the National Cancer Database (NCDB). International Journal Of Radiation Oncology • Biology • Physics 2018, 102: e335. DOI: 10.1016/j.ijrobp.2018.07.1028.
- Friedlaender G. The Cost of Innovation Roles of Industry, Regulatory Agencies, and the Clinician. Techniques In Orthopaedics 2018, 33: 132-134. DOI: 10.1097/bto.0000000000000287.
- Ibe I, Sahlstrom A, Nguyen M, Lindskog D, Friedlaender G, Lee F. Immuno-oncologic Approach to Musculoskeletal Tumors. Techniques In Orthopaedics 2018, 33: 140-147. DOI: 10.1097/bto.0000000000000305.
- Commentary: Art in Science: Mondino de' Liuzzi: The Restorer of AnatomyFriedlaender, GE, Friedlaender, LK: Commentary: Art in Science: Mondino de' Liuzzi: The Restorer of Anatomy. Di Matteo B, Tarabella V, Filardo G, Massimiliano M, Presti ML, Vigano A, Tomba P, Marcacci M. Clin Orthop and Rel Res 475:1791-1795 (2017).
- Russo GS, Rubio DR, Yacob A, Lindskog DM, Alomari AK, Friedlaender GE. Case of a Missed Giant Cell Tumor of Bone: An Opportunity to Observe its Natural History Disease. Connecticut Medicine 2016, 80: 399-403. PMID: 29782126.
- Friedlaender GE, Friedlaender LK. Saints Cosmas and Damian: Patron Saints of Medicine. Clinical Orthopaedics And Related Research® 2016, 474: 1765-1769. PMID: 27283584, PMCID: PMC4925431, DOI: 10.1007/s11999-016-4929-6.
- Friedlaender GE, Friedlaender, LK: Commentary: Art in Science: Nicolaes Tulp: The Overshadowed Subject in The Anatomy Lession of Dr. Nicolaes Tulp. Di Matteo B, Tarabella V, Filardo G, Tomba P, Vigano A, Marcacci M. Clin Orthop Rel Res 474:625-629 (2016)
- Edwards B, Jeray K, Bunta A, Macaulay W, Jones C, Tosi L, Sietsema D, Kaufman J, Murphy S, Goulet J, Saraykar S, Friedlaender G, Swiontkowski M, Dirschl D. The “Own the Bone” Site and Satisfaction Survey. Journal Of Clinical Densitometry 2014, 17: 426. DOI: 10.1016/j.jocd.2014.04.097.
- DiGiovanni C, Glazebrook M, Snel L, Beasley B, Lynch S, Friedlaender G. A review of the clinical experience with recombinant human platelet-derived growth factor-BB (rhPDGF-BB) in orthopaedic bone repair and regeneration. Current Orthopaedic Practice 2013, 24: 476-481. DOI: 10.1097/bco.0b013e3182a593e6.
- Friedlaender GE, Friedlaender LK. Art in Science: Enhancing Observational Skills. Clinical Orthopaedics And Related Research® 2013, 471: 2065-2067. PMID: 23609813, PMCID: PMC3676632, DOI: 10.1007/s11999-013-3000-0.
- Friedlaender GE, Lin S, Solchaga LA, Snel LB, Lynch SE. The role of recombinant human platelet-derived growth factor-BB (rhPDGF-BB) in orthopaedic bone repair and regeneration. Current Pharmaceutical Design 2013, 19: 3384-90. PMID: 23432673, DOI: 10.2174/1381612811319190005.
- Bible JE, Lee RS, Friedlaender GE. The Need for Increased Access to the U.S. Health-Care System. Journal Of Bone And Joint Surgery 2009, 91: 476-484. PMID: 19181995, DOI: 10.2106/jbjs.h.00735.
- Hollinger J, Schmitz J, Friedlaender G, Brown C, Boden S, Lynch S. 68 Therapeutic Opportunities for Bone Grafting. 2008, 1164-1175. DOI: 10.1016/b978-012369410-2.50070-x.
- Kusuma S, Mehta S, Sirkin M, Yates A, Miclau T, Templeton K, Friedlaender G. Measuring the Attitudes and Impact of the Eighty-Hour Workweek Rules on Orthopaedic Surgery Residents. Journal Of Bone And Joint Surgery 2007, 89: 679-685. PMID: 17332119, DOI: 10.2106/jbjs.f.00526.
- Friedlaender GE. The 80-hour Duty Week. Clinical Orthopaedics And Related Research® 2006, 449: 138-142. PMID: 16760807, DOI: 10.1097/01.blo.0000224038.31474.30.
- Turell M, Friedlaender G, Wang A, Thornhill T, Bellare A. The effect of counterface roughness on the wear of UHMWPE for rectangular wear paths. Wear 2005, 259: 984-991. DOI: 10.1016/j.wear.2005.01.050.
- Friedlaender G. Clinical experience of osteogenic protein-1 (OP-1) in the repair of bone defects and fractures of long bones. Progress In Inflammation Research 2004, 157-162. DOI: 10.1007/978-3-0348-7857-9_7.
- FRIEDLAENDER G, STRONG D, MANKIN H. 2. IMMUNOLOGY OF BONE ALLOGRAFTS: CURRENT KNOWLEDGE. 2003, 19-30. DOI: 10.1142/9789812791290_0002.
- DiCaprio MR, Friedlaender GE. Malignant bone tumors: limb sparing versus amputation. Journal Of The American Academy Of Orthopaedic Surgeons 2003, 11: 25-37. PMID: 12699369, DOI: 10.5435/00124635-200301000-00005.
- Giltaij L, Shimmin A, Friedlaender G. Osteogenic protein-1 (OP-1) in the repair of bone defects and fractures of long bones: clinical experience. Progress In Inflammation Research 2002, 193-205. DOI: 10.1007/978-3-0348-8121-0_10.
- Patel T, Erulkar J, Grauer J, Troiano N, Panjabi M, Friedlaender G. Osteogenic Protein-1 Overcomes the Inhibitory Effect of Nicotine on Posterolateral Lumbar Fusion. Spine 2001, 26: 1656-1661. PMID: 11474350, DOI: 10.1097/00007632-200108010-00004.
- Friedlaender G. OP-1 clinical studies. Journal Of Bone And Joint Surgery 2001, 83-A Suppl 1: s160-1. PMID: 11314795, DOI: 10.2106/00004623-200100002-00012.
- Grauer J, Patel T, Erulkar J, Troiano N, Panjabi M, Friedlaender G. Evaluation of OP-1 as a Graft Substitute for Intertransverse Process Lumbar Fusion. Spine 2001, 26: 127-133. PMID: 11154530, DOI: 10.1097/00007632-200101150-00004.
- Friedlaender GE, Perry CR, Cole JD, Cook SD, Cierny G, Muschler GF, Zych GA, Calhoun JH, LaForte AJ, Yin S. Osteogenic protein-1 (bone morphogenetic protein-7) in the treatment of tibial nonunions. Journal Of Bone And Joint Surgery 2001, 83-A Suppl 1: s151-8. PMID: 11314793, PMCID: PMC1425155, DOI: 10.2106/00004623-200100002-00010.
- Friedlaender G. Appropriate screening for prevention of infection transmission by musculoskeletal allografts. Instructional Course Lectures 2000, 49: 615-9. PMID: 10829217.
- Friedlaender G, Strong D, Tomford W, Mankin H. LONG-TERM FOLLOW-UP OF PATIENTS WITH OSTEOCHONDRAL ALLOGRAFTS A Correlation Between Immunologic Responses and Clinical Outcome. Orthopedic Clinics Of North America 1999, 30: 583-588. PMID: 10471763, DOI: 10.1016/s0030-5898(05)70111-5.
- Pelker R, Friedlaender G. The Nicolas Andry Award-1995 Fracture Healing; Radiation Induced Alterations. Clinical Orthopaedics And Related Research® 1997, 341: 267-282. PMID: 9269183, DOI: 10.1097/00003086-199708000-00038.
- Mankin* H, Mankin C, Akeson W, Dick H, Friedlaender G, Radin E, Simon M. A Curriculum for the Ideal Orthopaedic Residency. Clinical Orthopaedics And Related Research® 1997, 339: 270-281. PMID: 9186229, DOI: 10.1097/00003086-199706000-00036.
- 光一 石, 佳史 尾, 牧雄 太, 和人 伊, 万正 糸, Troiano N, Friedlaender G. MethotrexateおよびDoxorubicin (Adriamycin) はラット大腿骨の骨折治癒を遅延させる. Rinsho Yakuri/Japanese Journal Of Clinical Pharmacology And Therapeutics 1997, 28: 485-486. DOI: 10.3999/jscpt.28.485.
- 光一 石, 隆信 松, Troiano N, Friedlaender G. アドレアマイシンおよびメソトレキセート短期投与後の骨代謝の変化に関する実験的研究. Rinsho Yakuri/Japanese Journal Of Clinical Pharmacology And Therapeutics 1995, 26: 429-430. DOI: 10.3999/jscpt.26.429.
- Widmann R, Pelker R, Friedlaender G, Panjabi M, Peschel R. Effects of prefracture irradiation on the biomechanical parameters of fracture healing. Journal Of Orthopaedic Research® 1993, 11: 422-428. PMID: 8326449, DOI: 10.1002/jor.1100110315.
- Friedlaender G, Horowitz M. Immune responses to osteochondral allografts: nature and significance. Orthopedics 1992, 15: 1171-5. PMID: 1409127, DOI: 10.3928/0147-7447-19921001-08.
- Huo M, Friedlaender G, Salvati E. Bone graft and total hip arthroplasty A review. The Journal Of Arthroplasty 1992, 7: 109-120. PMID: 1613516, DOI: 10.1016/0883-5403(92)90003-9.
- Brown R, Pelker R, Friedlaender G, Peschel R, Panjabi M. Postfracture irradiation effects on the biomechanical and histologic parameters of fracture healing. Journal Of Orthopaedic Research® 1991, 9: 876-882. PMID: 1919851, DOI: 10.1002/jor.1100090614.
- Horowitz M, Friedlaender G. Induction of specific T-cell responsiveness to allogeneic bone. Journal Of Bone And Joint Surgery 1991, 73: 1157-68. PMID: 1716256, DOI: 10.2106/00004623-199173080-00004.
- Huo M, Troiano N, Pelker R, Gundberg C, Friedlaender G. The influence of ibuprofen on fracture repair: Biomechanical, biochemical, histologic, and histomorphometric parameters in rats. Journal Of Orthopaedic Research® 1991, 9: 383-390. PMID: 2010842, DOI: 10.1002/jor.1100090310.
- Huo M, Friedlaender G, Marsh J. Orthopaedic manifestations of sickle-cell disease. The Yale Journal Of Biology And Medicine 1990, 63: 195-207. PMID: 2238715, PMCID: PMC2589295.
- Pelker R, McKay J, Troiano N, Panjabi M, Friedlaender G. Allograft incorporation: A biomechanical evaluation in a rat model. Journal Of Orthopaedic Research® 1989, 7: 585-589. PMID: 2786956, DOI: 10.1002/jor.1100070417.
- Markbreiter L, Pelker R, Friedlaender G, Peschel R, Panjabi M. The effect of radiation on the fracture repair process. A biomechanical evaluation of a closed fracture in a rat model. Journal Of Orthopaedic Research® 1989, 7: 178-183. PMID: 2918417, DOI: 10.1002/jor.1100070204.
- Jennings T, Peterson L, Axiotis C, Friedlaender G, Cooke R, Rosai J. Angiosarcoma associated with foreign body material: A report of three cases. Cancer 1988, 62: 2436-2444. PMID: 3052791, DOI: 10.1002/1097-0142(19881201)62:11<2436::aid-cncr2820621132>3.0.co;2-j.
- Friedlaender G. Tissue transplantation: allocation and related issues. Transplantation Proceedings 1988, 20: 1017-21. PMID: 3279598.
- FRIEDLAENDER G. Bone Banking. Clinical Orthopaedics And Related Research® 1987, 225: 17-21. DOI: 10.1097/00003086-198712000-00004.
- Friedlaender G. Bone banking. In support of reconstructive surgery of the hip. Clinical Orthopaedics And Related Research® 1987, 17-21. PMID: 3119268.
- LINDSEY R, GROBMAN J, LEGGON R, PANJABI M, FRIEDLAENDER G. Effects of Bone Graft and Electrical Stimulation on the Strength of Healing Bony Defects in Dogs. Clinical Orthopaedics And Related Research® 1987, 222: 275-280. PMID: 3304757, DOI: 10.1097/00003086-198709000-00037.
- Friedlaender G. Bone grafts. The basic science rationale for clinical applications. Journal Of Bone And Joint Surgery 1987, 69: 786-90. PMID: 3298264, DOI: 10.2106/00004623-198769050-00026.
- Tomford W, Mankin H, Friedlaender G, Doppelt S, Gebhardt M. Methods of Banking Bone and Cartilage for Allograft Transplantation. Orthopedic Clinics Of North America 1987, 18: 241-247. PMID: 3550573, DOI: 10.1016/s0030-5898(20)30388-6.
- Trumble T, Friedlaender G. Allogeneic Bone in the Treatment of Tumors, Trauma, and Congenital Anomalies of the Hand. Orthopedic Clinics Of North America 1987, 18: 301-310. PMID: 3550577, DOI: 10.1016/s0030-5898(20)30393-x.
- FRIEDLAENDER G. Preface. Orthopedic Clinics Of North America 1987, 18: xiii-xiv. DOI: 10.1016/s0030-5898(20)30380-1.
- Pelker R, Friedlaender G. Biomechanical Aspects of Bone Autografts and Allografts. Orthopedic Clinics Of North America 1987, 18: 235-239. PMID: 3561975, DOI: 10.1016/s0030-5898(20)30387-4.
- Horowitz M, Friedlaender G. Immunologic Aspects of Bone Transplantation A Rationale for Future Studies. Orthopedic Clinics Of North America 1987, 18: 227-233. PMID: 2951639, DOI: 10.1016/s0030-5898(20)30386-2.
- Trumble T, Friedlaender G. Use of allogenic bone in hand injuries. Techniques In Orthopaedics 1986, 1: 79-83. DOI: 10.1097/00013611-198607000-00017.
- Ezekowitz M, Pope C, Sostman H, Smith E, Glickman M, Rapoport S, Sniderman K, Friedlaender G, Pelker R, Taylor F. Indium-111 platelet scintigraphy for the diagnosis of acute venous thrombosis. Circulation 1986, 73: 668-674. PMID: 3948370, DOI: 10.1161/01.cir.73.4.668.
- Panjabi M, Summers D, Pelker R, Videman T, Friedlaender G, Southwick W. Three‐dimensional load‐displacement curves due to froces on the cervical spine. Journal Of Orthopaedic Research® 1986, 4: 152-161. PMID: 3712124, DOI: 10.1002/jor.1100040203.
- Friedlaender G. Bone banking and clinical applications. Transplantation Proceedings 1985, 17: 99-104. PMID: 3907058.
- BURWELL R, FRIEDLAENDER G, MANKIN H. Current Perspectives and Future Directions. Clinical Orthopaedics And Related Research® 1985, 197: 141-157. PMID: 3893825, DOI: 10.1097/00003086-198507000-00017.
- Gould R, Rosenfield A, Friedlaender G. Loose Body Within the Glenohumeral Joint in Recurrent Anterior Dislocation. Journal Of Computer Assisted Tomography 1985, 9: 404-406. PMID: 3973177, DOI: 10.1097/00004728-198503000-00040.
- Warren S, Pelker R, Friedlaender G. Effects of short‐term Cyclosporin‐A on biomechanical properties of intact and fractured bone in the rat. Journal Of Orthopaedic Research® 1985, 3: 96-100. PMID: 3981300, DOI: 10.1002/jor.1100030112.
- Pelker R, Friedlaender G, Panjabi M, Markham T, Hausman M, Doganis A, McKay J. Chemotherapy‐induced alterations in the biomechanics of rat bone. Journal Of Orthopaedic Research® 1985, 3: 91-95. PMID: 3981299, DOI: 10.1002/jor.1100030111.
- Friedlaender G, Tross R, Doganis A, Kirkwood J, Baron R. Effects of chemotherapeutic agents on bone. I. Short-term methotrexate and doxorubicin (adriamycin) treatment in a rat model. Journal Of Bone And Joint Surgery 1984, 66: 602-7. PMID: 6707039, DOI: 10.2106/00004623-198466040-00016.
- Friedlaender G, Mankin H. Transplantation of Osteochondral Allografts. Annual Review Of Medicine 1984, 35: 311-324. PMID: 6372659, DOI: 10.1146/annurev.me.35.020184.001523.
- Friedlaender G, Strong D, Sell K. Studies on the antigenicity of bone. II. Donor-specific anti-HLA antibodies in human recipients of freeze-dried allografts. Journal Of Bone And Joint Surgery 1984, 66: 107-12. PMID: 6361041, DOI: 10.2106/00004623-198466010-00014.
- Pelker R, Friedlaender G, Panjabi M, Kapp D, Doganis A. Radiation‐induced alterations of fracture healing biomechanics. Journal Of Orthopaedic Research® 1984, 2: 90-96. PMID: 6491804, DOI: 10.1002/jor.1100020114.
- Friedlaender G. Editorial Comment. Clinical Orthopaedics And Related Research® 1983, 174: 2-4. DOI: 10.1097/00003086-198304000-00001.
- Tomford W, Doppelt S, Mankin H, Friedlaender G. 1983 Bone Bank Procedures. Clinical Orthopaedics And Related Research® 1983, 174: 15-21. PMID: 6339136, DOI: 10.1097/00003086-198304000-00003.
- Friedlaender G. Immune responses to osteochondral allografts. Current knowledge and future directions. Clinical Orthopaedics And Related Research® 1983, 58-68. PMID: 6339143.
- PELKER R, FRIEDLAENDER G, MARKHAM T. FROZEN AND FREEZE-DRIED BONE GRAFTS. Clinical Orthopaedics And Related Research® 1983, 174: 36-42. PMID: 6339142, DOI: 10.1097/00003086-198304000-00007.
- Pelker R, Friedlaender G, Markham T. Biomechanical Properties of Bone Allografts. Clinical Orthopaedics And Related Research® 1983, 174: 54-57. PMID: 6339144, DOI: 10.1097/00003086-198304000-00009.
- Pelker R, Friedlaender G, Markham T, Panjabi M, Moen C. Effects of freezing and freeze‐drying on the biomechanical properties of rat bone. Journal Of Orthopaedic Research® 1983, 1: 405-411. PMID: 6387075, DOI: 10.1002/jor.1100010409.
- Prosnitz L, Lawson J, Friedlaender G, Farber L, Pezzimenti J. Avascular necrosis of bone in Hodgkin's disease patients treated with combined modality therapy. Cancer 1981, 47: 2793-2797. PMID: 7260869, DOI: 10.1002/1097-0142(19810615)47:12<2793::aid-cncr2820471206>3.0.co;2-a.
- Friedlaender G, Mankin H. Bone banking: current methods and suggested guidelines. Instructional Course Lectures 1981, 30: 36-55. PMID: 6763618.
- Sepe W, Bowers G, Lawrence J, Friedlaender G, Koch R. Clinical Evaluation of Freezedried Bone Allografts in Periodontal Osseous Defects‐Part II. Journal Of Periodontology 1978, 49: 9-14. PMID: 340637, DOI: 10.1902/jop.1978.49.1.9.
- Panjabi M, White A, Keller D, Southwick W, Friedlaender G. Stability of the cervical spine under tension. Journal Of Biomechanics 1978, 11: 189-197. PMID: 690154, DOI: 10.1016/0021-9290(78)90012-x.
- Friedlaender G, Sell K, Bond J. The Impact of Tissue Banking on the Treatment of Musculoskeletal System Trauma. Military Medicine 1977, 142: 858-861. PMID: 412124, DOI: 10.1093/milmed/142.11.858.
- Friedlaender G, Sell K, Bond J. Role of Preserved Allografts in Neurosurgical Procedures. Military Medicine 1977, 142: 685-686. PMID: 408755, DOI: 10.1093/milmed/142.9.685.
- Bright R, Friedlaender G, Sell K. Tissue Banking: The United States Navy Tissue Bank. Military Medicine 1977, 142: 503-510. PMID: 407498, DOI: 10.1093/milmed/142.7.503.
- Epker B, Friedlaender G, Wolford L, West R. The use of freeze-dried bone in middle-third face advancements. Oral Surgery Oral Medicine Oral Pathology And Oral Radiology 1976, 42: 278-289. PMID: 787861, DOI: 10.1016/0030-4220(76)90161-4.
- Friedlaender G, Johnson R, Brand R, Southwick W. Treatment of pathological fractures. Connecticut Medicine 1975, 39: 765-72. PMID: 1204339.
- Friedlaender G, Mitchell M. A laboratory model for the study of the immunobiology of osteosarcoma. Cancer 1975, 36: 1631-1639. PMID: 172215, DOI: 10.1002/1097-0142(197511)36:5<1631::aid-cncr2820360516>3.0.co;2-w.
- Yale Orthopaedics/Musculoskeletal OncologyYale Physicians Building800 Howard Avenue, Ste 1st floorNew Haven, CT 06519
Biography
Gary E. Friedlaender, MD, is an orthopaedic surgeon who specializes in musculoskeletal oncology, or benign and malignant tumors of the bones. He leads the Sarcoma Program at Smilow Cancer Hospital, treating rare cancers that involve the bones, cartilage, muscle and other tissues in the body.
Dr. Friedlaender has achieved national recognition for his surgical innovations, including development of limb-salvaging techniques that are now considered essential to orthopaedic oncology surgery.
However, he considers his close connections with his patients to be the key element in his approach to orthopaedics. Good physicians are great communicators—skilled at discovering information that patients may be reluctant to share, or that they have misinterpreted or forgotten, Dr. Friedlaender says. He tells new doctors, “In asking what is bothering the patient, we must convey our interest in hearing what they have to say. Sit down, make eye contact, ask open-ended questions, and, whatever you do, don’t interrupt.”
Dr. Friedlaender is a professor of orthopaedics and rehabilitation at Yale School of Medicine. He was chair of the department for 30 years, and was responsible for making Yale Orthopaedics & Rehabilitation a leader in the field. He has served as president of several important professional organizations, including the American Orthopaedic Association. Connecticut Magazine has included Dr. Friedlaender in its annual lists of Top Docs in the state.
He says he decided to enter the medical field when he was a child, after watching his father, also a physician, at work. He chose to pursue orthopaedics because he admired the doctors who treated the musculoskeletal injuries he had as a child. He has seen the field change dramatically since then. When he was a resident in the 1970s, the survival rate for osteosarcoma, the most common type of bone cancer, was 15 to 20 percent; now the cure rate is 80 percent.
“I get joy from working in an environment like Yale, and even more so now with Smilow Cancer Hospital,” Dr. Friedlaender says. “There are so many capable, creative and energetic physicians and they are all under one roof. The scientists, nursing staff, and support individuals make the work in oncology not only possible, but rewarding. It’s all about the patient.”
Titles
- Wayne O. Southwick Professor of Orthopaedics and Rehabilitation and Professor of Pathology
- Chair Emeritus, Department of Orthopaedics and Rehabilitation
Education & Training
- FellowMassachusetts General Hospital (1983)
- FellowBerg-Sloat Traveling Fellowship (Karolinska Inst,Oxford Univ,Univ Nottingham, Royal National Ortho), Sweden and England Bone Biology and Tumor Immunobiology (1976)
- ResidentYale-New Haven Hospital (1974)
- FellowNIH-Post-doctoral Research Fellowship, Yale University School of Medicine, New Haven, CT Oncology and Immunobiology (1973)
- ResidentUniversity of Michigan (1971)
- InternUniversity of Michigan Medical Center, Ann Arbor, Michigan Surgery (1970)
- MDUniversity of Michigan Medical School (1969)
- FellowFord Foundation Fellowship in Reproductive Biology, University of Michigan, Ann Arbor, Michigan Reproductive Immunobiology (1969)
- BSUniversity of Michigan, Zoology (1967)
Additional Information
- Tipton Leadership Award: American Academy of Orthopaedic Surgeons (2014)
- Distinguished Contributions to Orthopaedics: American Orthopaedic Association (2013)
- Inaugural Stefansky Visiting Professor for Communication Skills: University of Toronto (2012)
- Crawford J. Campbell Visiting Professor: Albany Medical Center (2012)
- Allen Fellowship Distinguished Visiting Professor: Case Western Reserve School of Medicine (2012)
- Alan DeForest Smith Lecturer: New York Orthopaedic Hospital/Columbia University (2011)
- President: American Orthopaedic Association (2010)
- Distinguished Achievement Award: University of Michigan Medical Alumni Association (2008)
- Edward T. Smith Visiting Professor: University of Texas (Houston) (2006)
- Fischer-Owen Lecturer: University of Louisville (2005)
- AB of Orthopaedic Surgery, Orthopaedic Surgery (1975)
- National Institutes of Health (2002 - 2003): NIH Consensus Development Conference On Total Knee Replacements Planning Committee
- American Academy of Orthopaedic Surgeons (2001 - 2002): Council of Subspecialty Societies
- National Institutes of Health (2001 - Present): Center for Scientific Review, Bone, Muscle, Connective Tissue Boundaries Study Section
- Orthopaedic Research and Education Foundation (2000 - 2005): Grant Peer Review Committee
- Journal of the American Academy of Orthopaedic Surgeons (2000 - Present): Editorial Review Board
- Journal Spine (2000 - Present): Board of Associate Editors
- National Institutes of Health (1998 - 2002): NIAMS Council
- Food and Drug Administration (1996 - 1997): FDA Panel on Blood and Blood Products
- Arthritis Association (1996 - 1997): Medical Advisory Board
- The Cancer Journal (1994 - 2007): Board of Associate Editors
- Friedlaender GE. CORR Insights®: Imposter Syndrome Among Surgeons is Associated With Intolerance of Uncertainty and Lower Confidence in Problem Solving. Clinical Orthopaedics And Related Research® 2022, 481: 672-674. PMID: 36166271, PMCID: PMC10013620, DOI: 10.1097/corr.0000000000002427.
- Friedlaender GE, Friedlaender LK. Reply to the Letter to the Editor: Art in Science: Quackery and Promises Not Kept. Clinical Orthopaedics And Related Research® 2022, 480: 2060-2060. PMID: 36001023, PMCID: PMC9473757, DOI: 10.1097/corr.0000000000002350.
- Friedlaender GE, Friedlaender LK. Art in Science: Quackery and Promises Not Kept. Clinical Orthopaedics And Related Research® 2022, 480: 1458-1460. PMID: 35767816, PMCID: PMC9278922, DOI: 10.1097/corr.0000000000002290.
- Friedlaender GE, Friedlaender LK. Art in Science: Alchemy As Seen Through The Eyes of David Teniers the Younger. Clinical Orthopaedics And Related Research® 2021, 480: 235-236. PMID: 34870955, PMCID: PMC8747614, DOI: 10.1097/corr.0000000000002069.
- Chan SM, Moran J, Friedlaender LK, Friedlaender GE. Art in Science: The Boxer at Rest. Clinical Orthopaedics And Related Research® 2021, 479: 1441-1443. PMID: 34106904, PMCID: PMC8208444, DOI: 10.1097/corr.0000000000001847.
- Flores M, Friedlaender LK, Friedlaender GE. Art in Science-Humility: As Portrayed by Pietro Lorenzetti. Clinical Orthopaedics And Related Research® 2021, 479: 458-460. PMID: 33543878, PMCID: PMC7899731, DOI: 10.1097/corr.0000000000001666.
- Chan SM, Friedlaender GE, Friedlaender LK. Art in Science-Goya to Dr. Arrieta: An Illustration of Patient-Physician Trust. Clinical Orthopaedics And Related Research® 2020, 478: 2221-2224. PMID: 32898044, PMCID: PMC7491894, DOI: 10.1097/corr.0000000000001470.
- Friedlaender GE, Friedlaender LK. Art in Science: Pieter Bruegel the Elder and the Plague. Clinical Orthopaedics And Related Research® 2020, 478: 1416-1418. PMID: 32574469, PMCID: PMC7310395, DOI: 10.1097/corr.0000000000001325.
- Jiang W, Latich I, Lindskog D, Friedlaender G, Lee F. Progression of Femoral Osteolytic Metastases after Intramedullary Nailing and Subsequent Salvage Techniques. Cancers 2024, 16: 2812. PMID: 39199585, PMCID: PMC11352437, DOI: 10.3390/cancers16162812.
- Jiang W, Caruana D, Dussik C, Conway D, Latich I, Chapiro J, Lindskog D, Friedlaender G, Lee F. Bone Mass Changes Following Percutaneous Radiofrequency Ablation, Osteoplasty, Reinforcement, and Internal Fixation of Periacetabular Osteolytic Metastases. Journal Of Clinical Medicine 2023, 12: 4613. PMID: 37510728, PMCID: PMC10380351, DOI: 10.3390/jcm12144613.
- Jiang W, Friedlaender G, Lindskog D, Latich I, Lee F. Comparison of Percutaneous Interventional Ablation-Osteoplasty-Reinforcement-Internal Fixation (AORIF), Long Intramedullary Nailing, and Hemiarthroplasty for the Treatment of Focal Metastatic Osteolytic Lesions in the Femoral Head and Neck. CardioVascular And Interventional Radiology 2023, 46: 649-657. PMID: 37052716, DOI: 10.1007/s00270-023-03425-x.
- Dussik C, Toombs C, Alder K, Yu K, Berson E, Ibe I, Li F, Lindskog D, Friedlaender G, Latich I, Lee F. Percutaneous Ablation, Osteoplasty, Reinforcement, and Internal Fixation for Pain and Ambulatory Function in Periacetabular Osteolytic Malignancies. Radiology 2023, 307: e221401. PMID: 36916888, DOI: 10.1148/radiol.221401.
- Pirkle S, Chen A, Samora J, Friedlaender G. What’s Important: Ortho, I Screwed Up. Journal Of Bone And Joint Surgery 2023, 105: 962-964. PMID: 36728460, DOI: 10.2106/jbjs.22.01214.
- Samuel AM, Munger AM, Lee FY, Friedlaender GE, Ibe IK, Lindskog DM. Bone Scans Have Little Utility in the Evaluation of Well-Differentiated Cartilaginous Lesions of the Humerus. Orthopedics 2020, 43: e498-e502. PMID: 32882054, DOI: 10.3928/01477447-20200827-05.
- Lee FY, Latich I, Toombs C, Mungur A, Conway D, Alder K, Ibe I, Lindskog D, Friedlaender G. Minimally Invasive Image-Guided Ablation, Osteoplasty, Reinforcement, and Internal Fixation (AORIF) for Osteolytic Lesions in the Pelvis and Periarticular Regions of Weight-Bearing Bones. Journal Of Vascular And Interventional Radiology 2020, 31: 649-658.e1. PMID: 32139256, DOI: 10.1016/j.jvir.2019.11.029.
- Miccio J, Jairam V, Gao S, Augustyn A, Oladeru O, Onderdonk B, Costa J, Han D, Khan S, Friedlaender G, Lindskog D, Deshpande H, Tara H, Osborn H, Roberts K, Patel K. Predictors of Lymph Node Involvement by Soft Tissue Sarcoma: An Analysis of the National Cancer Database (NCDB). International Journal Of Radiation Oncology • Biology • Physics 2018, 102: e335. DOI: 10.1016/j.ijrobp.2018.07.1028.
- Friedlaender G. The Cost of Innovation Roles of Industry, Regulatory Agencies, and the Clinician. Techniques In Orthopaedics 2018, 33: 132-134. DOI: 10.1097/bto.0000000000000287.
- Ibe I, Sahlstrom A, Nguyen M, Lindskog D, Friedlaender G, Lee F. Immuno-oncologic Approach to Musculoskeletal Tumors. Techniques In Orthopaedics 2018, 33: 140-147. DOI: 10.1097/bto.0000000000000305.
- Commentary: Art in Science: Mondino de' Liuzzi: The Restorer of AnatomyFriedlaender, GE, Friedlaender, LK: Commentary: Art in Science: Mondino de' Liuzzi: The Restorer of Anatomy. Di Matteo B, Tarabella V, Filardo G, Massimiliano M, Presti ML, Vigano A, Tomba P, Marcacci M. Clin Orthop and Rel Res 475:1791-1795 (2017).
- Russo GS, Rubio DR, Yacob A, Lindskog DM, Alomari AK, Friedlaender GE. Case of a Missed Giant Cell Tumor of Bone: An Opportunity to Observe its Natural History Disease. Connecticut Medicine 2016, 80: 399-403. PMID: 29782126.
- Friedlaender GE, Friedlaender LK. Saints Cosmas and Damian: Patron Saints of Medicine. Clinical Orthopaedics And Related Research® 2016, 474: 1765-1769. PMID: 27283584, PMCID: PMC4925431, DOI: 10.1007/s11999-016-4929-6.
- Friedlaender GE, Friedlaender, LK: Commentary: Art in Science: Nicolaes Tulp: The Overshadowed Subject in The Anatomy Lession of Dr. Nicolaes Tulp. Di Matteo B, Tarabella V, Filardo G, Tomba P, Vigano A, Marcacci M. Clin Orthop Rel Res 474:625-629 (2016)
- Edwards B, Jeray K, Bunta A, Macaulay W, Jones C, Tosi L, Sietsema D, Kaufman J, Murphy S, Goulet J, Saraykar S, Friedlaender G, Swiontkowski M, Dirschl D. The “Own the Bone” Site and Satisfaction Survey. Journal Of Clinical Densitometry 2014, 17: 426. DOI: 10.1016/j.jocd.2014.04.097.
- DiGiovanni C, Glazebrook M, Snel L, Beasley B, Lynch S, Friedlaender G. A review of the clinical experience with recombinant human platelet-derived growth factor-BB (rhPDGF-BB) in orthopaedic bone repair and regeneration. Current Orthopaedic Practice 2013, 24: 476-481. DOI: 10.1097/bco.0b013e3182a593e6.
- Friedlaender GE, Friedlaender LK. Art in Science: Enhancing Observational Skills. Clinical Orthopaedics And Related Research® 2013, 471: 2065-2067. PMID: 23609813, PMCID: PMC3676632, DOI: 10.1007/s11999-013-3000-0.
- Friedlaender GE, Lin S, Solchaga LA, Snel LB, Lynch SE. The role of recombinant human platelet-derived growth factor-BB (rhPDGF-BB) in orthopaedic bone repair and regeneration. Current Pharmaceutical Design 2013, 19: 3384-90. PMID: 23432673, DOI: 10.2174/1381612811319190005.
- Bible JE, Lee RS, Friedlaender GE. The Need for Increased Access to the U.S. Health-Care System. Journal Of Bone And Joint Surgery 2009, 91: 476-484. PMID: 19181995, DOI: 10.2106/jbjs.h.00735.
- Hollinger J, Schmitz J, Friedlaender G, Brown C, Boden S, Lynch S. 68 Therapeutic Opportunities for Bone Grafting. 2008, 1164-1175. DOI: 10.1016/b978-012369410-2.50070-x.
- Kusuma S, Mehta S, Sirkin M, Yates A, Miclau T, Templeton K, Friedlaender G. Measuring the Attitudes and Impact of the Eighty-Hour Workweek Rules on Orthopaedic Surgery Residents. Journal Of Bone And Joint Surgery 2007, 89: 679-685. PMID: 17332119, DOI: 10.2106/jbjs.f.00526.
- Friedlaender GE. The 80-hour Duty Week. Clinical Orthopaedics And Related Research® 2006, 449: 138-142. PMID: 16760807, DOI: 10.1097/01.blo.0000224038.31474.30.
- Turell M, Friedlaender G, Wang A, Thornhill T, Bellare A. The effect of counterface roughness on the wear of UHMWPE for rectangular wear paths. Wear 2005, 259: 984-991. DOI: 10.1016/j.wear.2005.01.050.
- Friedlaender G. Clinical experience of osteogenic protein-1 (OP-1) in the repair of bone defects and fractures of long bones. Progress In Inflammation Research 2004, 157-162. DOI: 10.1007/978-3-0348-7857-9_7.
- FRIEDLAENDER G, STRONG D, MANKIN H. 2. IMMUNOLOGY OF BONE ALLOGRAFTS: CURRENT KNOWLEDGE. 2003, 19-30. DOI: 10.1142/9789812791290_0002.
- DiCaprio MR, Friedlaender GE. Malignant bone tumors: limb sparing versus amputation. Journal Of The American Academy Of Orthopaedic Surgeons 2003, 11: 25-37. PMID: 12699369, DOI: 10.5435/00124635-200301000-00005.
- Giltaij L, Shimmin A, Friedlaender G. Osteogenic protein-1 (OP-1) in the repair of bone defects and fractures of long bones: clinical experience. Progress In Inflammation Research 2002, 193-205. DOI: 10.1007/978-3-0348-8121-0_10.
- Patel T, Erulkar J, Grauer J, Troiano N, Panjabi M, Friedlaender G. Osteogenic Protein-1 Overcomes the Inhibitory Effect of Nicotine on Posterolateral Lumbar Fusion. Spine 2001, 26: 1656-1661. PMID: 11474350, DOI: 10.1097/00007632-200108010-00004.
- Friedlaender G. OP-1 clinical studies. Journal Of Bone And Joint Surgery 2001, 83-A Suppl 1: s160-1. PMID: 11314795, DOI: 10.2106/00004623-200100002-00012.
- Grauer J, Patel T, Erulkar J, Troiano N, Panjabi M, Friedlaender G. Evaluation of OP-1 as a Graft Substitute for Intertransverse Process Lumbar Fusion. Spine 2001, 26: 127-133. PMID: 11154530, DOI: 10.1097/00007632-200101150-00004.
- Friedlaender GE, Perry CR, Cole JD, Cook SD, Cierny G, Muschler GF, Zych GA, Calhoun JH, LaForte AJ, Yin S. Osteogenic protein-1 (bone morphogenetic protein-7) in the treatment of tibial nonunions. Journal Of Bone And Joint Surgery 2001, 83-A Suppl 1: s151-8. PMID: 11314793, PMCID: PMC1425155, DOI: 10.2106/00004623-200100002-00010.
- Friedlaender G. Appropriate screening for prevention of infection transmission by musculoskeletal allografts. Instructional Course Lectures 2000, 49: 615-9. PMID: 10829217.
- Friedlaender G, Strong D, Tomford W, Mankin H. LONG-TERM FOLLOW-UP OF PATIENTS WITH OSTEOCHONDRAL ALLOGRAFTS A Correlation Between Immunologic Responses and Clinical Outcome. Orthopedic Clinics Of North America 1999, 30: 583-588. PMID: 10471763, DOI: 10.1016/s0030-5898(05)70111-5.
- Pelker R, Friedlaender G. The Nicolas Andry Award-1995 Fracture Healing; Radiation Induced Alterations. Clinical Orthopaedics And Related Research® 1997, 341: 267-282. PMID: 9269183, DOI: 10.1097/00003086-199708000-00038.
- Mankin* H, Mankin C, Akeson W, Dick H, Friedlaender G, Radin E, Simon M. A Curriculum for the Ideal Orthopaedic Residency. Clinical Orthopaedics And Related Research® 1997, 339: 270-281. PMID: 9186229, DOI: 10.1097/00003086-199706000-00036.
- 光一 石, 佳史 尾, 牧雄 太, 和人 伊, 万正 糸, Troiano N, Friedlaender G. MethotrexateおよびDoxorubicin (Adriamycin) はラット大腿骨の骨折治癒を遅延させる. Rinsho Yakuri/Japanese Journal Of Clinical Pharmacology And Therapeutics 1997, 28: 485-486. DOI: 10.3999/jscpt.28.485.
- 光一 石, 隆信 松, Troiano N, Friedlaender G. アドレアマイシンおよびメソトレキセート短期投与後の骨代謝の変化に関する実験的研究. Rinsho Yakuri/Japanese Journal Of Clinical Pharmacology And Therapeutics 1995, 26: 429-430. DOI: 10.3999/jscpt.26.429.
- Widmann R, Pelker R, Friedlaender G, Panjabi M, Peschel R. Effects of prefracture irradiation on the biomechanical parameters of fracture healing. Journal Of Orthopaedic Research® 1993, 11: 422-428. PMID: 8326449, DOI: 10.1002/jor.1100110315.
- Friedlaender G, Horowitz M. Immune responses to osteochondral allografts: nature and significance. Orthopedics 1992, 15: 1171-5. PMID: 1409127, DOI: 10.3928/0147-7447-19921001-08.
- Huo M, Friedlaender G, Salvati E. Bone graft and total hip arthroplasty A review. The Journal Of Arthroplasty 1992, 7: 109-120. PMID: 1613516, DOI: 10.1016/0883-5403(92)90003-9.
- Brown R, Pelker R, Friedlaender G, Peschel R, Panjabi M. Postfracture irradiation effects on the biomechanical and histologic parameters of fracture healing. Journal Of Orthopaedic Research® 1991, 9: 876-882. PMID: 1919851, DOI: 10.1002/jor.1100090614.
- Horowitz M, Friedlaender G. Induction of specific T-cell responsiveness to allogeneic bone. Journal Of Bone And Joint Surgery 1991, 73: 1157-68. PMID: 1716256, DOI: 10.2106/00004623-199173080-00004.
- Huo M, Troiano N, Pelker R, Gundberg C, Friedlaender G. The influence of ibuprofen on fracture repair: Biomechanical, biochemical, histologic, and histomorphometric parameters in rats. Journal Of Orthopaedic Research® 1991, 9: 383-390. PMID: 2010842, DOI: 10.1002/jor.1100090310.
- Huo M, Friedlaender G, Marsh J. Orthopaedic manifestations of sickle-cell disease. The Yale Journal Of Biology And Medicine 1990, 63: 195-207. PMID: 2238715, PMCID: PMC2589295.
- Pelker R, McKay J, Troiano N, Panjabi M, Friedlaender G. Allograft incorporation: A biomechanical evaluation in a rat model. Journal Of Orthopaedic Research® 1989, 7: 585-589. PMID: 2786956, DOI: 10.1002/jor.1100070417.
- Markbreiter L, Pelker R, Friedlaender G, Peschel R, Panjabi M. The effect of radiation on the fracture repair process. A biomechanical evaluation of a closed fracture in a rat model. Journal Of Orthopaedic Research® 1989, 7: 178-183. PMID: 2918417, DOI: 10.1002/jor.1100070204.
- Jennings T, Peterson L, Axiotis C, Friedlaender G, Cooke R, Rosai J. Angiosarcoma associated with foreign body material: A report of three cases. Cancer 1988, 62: 2436-2444. PMID: 3052791, DOI: 10.1002/1097-0142(19881201)62:11<2436::aid-cncr2820621132>3.0.co;2-j.
- Friedlaender G. Tissue transplantation: allocation and related issues. Transplantation Proceedings 1988, 20: 1017-21. PMID: 3279598.
- FRIEDLAENDER G. Bone Banking. Clinical Orthopaedics And Related Research® 1987, 225: 17-21. DOI: 10.1097/00003086-198712000-00004.
- Friedlaender G. Bone banking. In support of reconstructive surgery of the hip. Clinical Orthopaedics And Related Research® 1987, 17-21. PMID: 3119268.
- LINDSEY R, GROBMAN J, LEGGON R, PANJABI M, FRIEDLAENDER G. Effects of Bone Graft and Electrical Stimulation on the Strength of Healing Bony Defects in Dogs. Clinical Orthopaedics And Related Research® 1987, 222: 275-280. PMID: 3304757, DOI: 10.1097/00003086-198709000-00037.
- Friedlaender G. Bone grafts. The basic science rationale for clinical applications. Journal Of Bone And Joint Surgery 1987, 69: 786-90. PMID: 3298264, DOI: 10.2106/00004623-198769050-00026.
- Tomford W, Mankin H, Friedlaender G, Doppelt S, Gebhardt M. Methods of Banking Bone and Cartilage for Allograft Transplantation. Orthopedic Clinics Of North America 1987, 18: 241-247. PMID: 3550573, DOI: 10.1016/s0030-5898(20)30388-6.
- Trumble T, Friedlaender G. Allogeneic Bone in the Treatment of Tumors, Trauma, and Congenital Anomalies of the Hand. Orthopedic Clinics Of North America 1987, 18: 301-310. PMID: 3550577, DOI: 10.1016/s0030-5898(20)30393-x.
- FRIEDLAENDER G. Preface. Orthopedic Clinics Of North America 1987, 18: xiii-xiv. DOI: 10.1016/s0030-5898(20)30380-1.
- Pelker R, Friedlaender G. Biomechanical Aspects of Bone Autografts and Allografts. Orthopedic Clinics Of North America 1987, 18: 235-239. PMID: 3561975, DOI: 10.1016/s0030-5898(20)30387-4.
- Horowitz M, Friedlaender G. Immunologic Aspects of Bone Transplantation A Rationale for Future Studies. Orthopedic Clinics Of North America 1987, 18: 227-233. PMID: 2951639, DOI: 10.1016/s0030-5898(20)30386-2.
- Trumble T, Friedlaender G. Use of allogenic bone in hand injuries. Techniques In Orthopaedics 1986, 1: 79-83. DOI: 10.1097/00013611-198607000-00017.
- Ezekowitz M, Pope C, Sostman H, Smith E, Glickman M, Rapoport S, Sniderman K, Friedlaender G, Pelker R, Taylor F. Indium-111 platelet scintigraphy for the diagnosis of acute venous thrombosis. Circulation 1986, 73: 668-674. PMID: 3948370, DOI: 10.1161/01.cir.73.4.668.
- Panjabi M, Summers D, Pelker R, Videman T, Friedlaender G, Southwick W. Three‐dimensional load‐displacement curves due to froces on the cervical spine. Journal Of Orthopaedic Research® 1986, 4: 152-161. PMID: 3712124, DOI: 10.1002/jor.1100040203.
- Friedlaender G. Bone banking and clinical applications. Transplantation Proceedings 1985, 17: 99-104. PMID: 3907058.
- BURWELL R, FRIEDLAENDER G, MANKIN H. Current Perspectives and Future Directions. Clinical Orthopaedics And Related Research® 1985, 197: 141-157. PMID: 3893825, DOI: 10.1097/00003086-198507000-00017.
- Gould R, Rosenfield A, Friedlaender G. Loose Body Within the Glenohumeral Joint in Recurrent Anterior Dislocation. Journal Of Computer Assisted Tomography 1985, 9: 404-406. PMID: 3973177, DOI: 10.1097/00004728-198503000-00040.
- Warren S, Pelker R, Friedlaender G. Effects of short‐term Cyclosporin‐A on biomechanical properties of intact and fractured bone in the rat. Journal Of Orthopaedic Research® 1985, 3: 96-100. PMID: 3981300, DOI: 10.1002/jor.1100030112.
- Pelker R, Friedlaender G, Panjabi M, Markham T, Hausman M, Doganis A, McKay J. Chemotherapy‐induced alterations in the biomechanics of rat bone. Journal Of Orthopaedic Research® 1985, 3: 91-95. PMID: 3981299, DOI: 10.1002/jor.1100030111.
- Friedlaender G, Tross R, Doganis A, Kirkwood J, Baron R. Effects of chemotherapeutic agents on bone. I. Short-term methotrexate and doxorubicin (adriamycin) treatment in a rat model. Journal Of Bone And Joint Surgery 1984, 66: 602-7. PMID: 6707039, DOI: 10.2106/00004623-198466040-00016.
- Friedlaender G, Mankin H. Transplantation of Osteochondral Allografts. Annual Review Of Medicine 1984, 35: 311-324. PMID: 6372659, DOI: 10.1146/annurev.me.35.020184.001523.
- Friedlaender G, Strong D, Sell K. Studies on the antigenicity of bone. II. Donor-specific anti-HLA antibodies in human recipients of freeze-dried allografts. Journal Of Bone And Joint Surgery 1984, 66: 107-12. PMID: 6361041, DOI: 10.2106/00004623-198466010-00014.
- Pelker R, Friedlaender G, Panjabi M, Kapp D, Doganis A. Radiation‐induced alterations of fracture healing biomechanics. Journal Of Orthopaedic Research® 1984, 2: 90-96. PMID: 6491804, DOI: 10.1002/jor.1100020114.
- Friedlaender G. Editorial Comment. Clinical Orthopaedics And Related Research® 1983, 174: 2-4. DOI: 10.1097/00003086-198304000-00001.
- Tomford W, Doppelt S, Mankin H, Friedlaender G. 1983 Bone Bank Procedures. Clinical Orthopaedics And Related Research® 1983, 174: 15-21. PMID: 6339136, DOI: 10.1097/00003086-198304000-00003.
- Friedlaender G. Immune responses to osteochondral allografts. Current knowledge and future directions. Clinical Orthopaedics And Related Research® 1983, 58-68. PMID: 6339143.
- PELKER R, FRIEDLAENDER G, MARKHAM T. FROZEN AND FREEZE-DRIED BONE GRAFTS. Clinical Orthopaedics And Related Research® 1983, 174: 36-42. PMID: 6339142, DOI: 10.1097/00003086-198304000-00007.
- Pelker R, Friedlaender G, Markham T. Biomechanical Properties of Bone Allografts. Clinical Orthopaedics And Related Research® 1983, 174: 54-57. PMID: 6339144, DOI: 10.1097/00003086-198304000-00009.
- Pelker R, Friedlaender G, Markham T, Panjabi M, Moen C. Effects of freezing and freeze‐drying on the biomechanical properties of rat bone. Journal Of Orthopaedic Research® 1983, 1: 405-411. PMID: 6387075, DOI: 10.1002/jor.1100010409.
- Prosnitz L, Lawson J, Friedlaender G, Farber L, Pezzimenti J. Avascular necrosis of bone in Hodgkin's disease patients treated with combined modality therapy. Cancer 1981, 47: 2793-2797. PMID: 7260869, DOI: 10.1002/1097-0142(19810615)47:12<2793::aid-cncr2820471206>3.0.co;2-a.
- Friedlaender G, Mankin H. Bone banking: current methods and suggested guidelines. Instructional Course Lectures 1981, 30: 36-55. PMID: 6763618.
- Sepe W, Bowers G, Lawrence J, Friedlaender G, Koch R. Clinical Evaluation of Freezedried Bone Allografts in Periodontal Osseous Defects‐Part II. Journal Of Periodontology 1978, 49: 9-14. PMID: 340637, DOI: 10.1902/jop.1978.49.1.9.
- Panjabi M, White A, Keller D, Southwick W, Friedlaender G. Stability of the cervical spine under tension. Journal Of Biomechanics 1978, 11: 189-197. PMID: 690154, DOI: 10.1016/0021-9290(78)90012-x.
- Friedlaender G, Sell K, Bond J. The Impact of Tissue Banking on the Treatment of Musculoskeletal System Trauma. Military Medicine 1977, 142: 858-861. PMID: 412124, DOI: 10.1093/milmed/142.11.858.
- Friedlaender G, Sell K, Bond J. Role of Preserved Allografts in Neurosurgical Procedures. Military Medicine 1977, 142: 685-686. PMID: 408755, DOI: 10.1093/milmed/142.9.685.
- Bright R, Friedlaender G, Sell K. Tissue Banking: The United States Navy Tissue Bank. Military Medicine 1977, 142: 503-510. PMID: 407498, DOI: 10.1093/milmed/142.7.503.
- Epker B, Friedlaender G, Wolford L, West R. The use of freeze-dried bone in middle-third face advancements. Oral Surgery Oral Medicine Oral Pathology And Oral Radiology 1976, 42: 278-289. PMID: 787861, DOI: 10.1016/0030-4220(76)90161-4.
- Friedlaender G, Johnson R, Brand R, Southwick W. Treatment of pathological fractures. Connecticut Medicine 1975, 39: 765-72. PMID: 1204339.
- Friedlaender G, Mitchell M. A laboratory model for the study of the immunobiology of osteosarcoma. Cancer 1975, 36: 1631-1639. PMID: 172215, DOI: 10.1002/1097-0142(197511)36:5<1631::aid-cncr2820360516>3.0.co;2-w.
- Yale Orthopaedics/Musculoskeletal OncologyYale Physicians Building800 Howard Avenue, Ste 1st floorNew Haven, CT 06519
- Yale Orthopaedics/Musculoskeletal OncologyYale Physicians Building800 Howard Avenue, Ste 1st floorNew Haven, CT 06519