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Exercise as a Standard of Care for Breast Cancer

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  • 00:00 --> 00:02Funding for Yale Cancer Answers is
  • 00:02 --> 00:04provided by Smilow Cancer Hospital.
  • 00:06 --> 00:08Welcome to Yale Cancer Answers
  • 00:08 --> 00:10with Doctor Anees Chagpar.
  • 00:10 --> 00:12Yale Cancer Answers features the
  • 00:12 --> 00:13latest information on cancer
  • 00:13 --> 00:15care by welcoming oncologists and
  • 00:15 --> 00:17specialists who are on the forefront
  • 00:17 --> 00:19of the battle to fight cancer.
  • 00:19 --> 00:21This week, it's a conversation about
  • 00:21 --> 00:23the benefits of exercise in the care
  • 00:23 --> 00:25of patients with breast cancer with
  • 00:25 --> 00:27doctors Tara Sanft and Melinda Irwin.
  • 00:27 --> 00:29Doctor Sanft is an associate professor
  • 00:29 --> 00:31of medicine and medical oncology
  • 00:31 --> 00:32and Dr. Irwin
  • 00:32 --> 00:33is the Susan Dwight Bliss
  • 00:33 --> 00:35Professor of Epidemiology at the
  • 00:35 --> 00:37Yale School of Medicine,
  • 00:37 --> 00:39where Doctor Chagpar is a
  • 00:39 --> 00:40professor of surgical oncology.
  • 00:41 --> 00:43So maybe we'll start off with each
  • 00:43 --> 00:45of you telling us a little bit more
  • 00:45 --> 00:47about yourselves and what it is you do.
  • 00:47 --> 00:49Tara, can we start with you?
  • 00:49 --> 00:51So I'm a breast medical oncologist.
  • 00:51 --> 00:55I've been practicing for about 14 years.
  • 00:55 --> 00:57I see patients who are recently
  • 00:57 --> 00:59diagnosed with breast cancer,
  • 00:59 --> 01:03and I also run a survivorship program
  • 01:03 --> 01:06here where we have a multidisciplinary
  • 01:06 --> 01:08approach to cancer survivorship
  • 01:08 --> 01:11in a clinic that includes a
  • 01:11 --> 01:12physical therapist, a dietitian,
  • 01:12 --> 01:15a social worker, and a physician's assistant.
  • 01:15 --> 01:17There we see patients of all
  • 01:17 --> 01:19diagnoses after treatment.
  • 01:19 --> 01:21And Melinda, can you tell us a little
  • 01:21 --> 01:22bit more about yourself and what you do?
  • 01:23 --> 01:27Sure, happy to. So I am trained in both
  • 01:27 --> 01:30epidemiology and exercise Physiology.
  • 01:30 --> 01:33And for about the past 20 years I've
  • 01:33 --> 01:35been leading, along with colleagues such
  • 01:35 --> 01:38as Tara, clinical trials where we look
  • 01:38 --> 01:41at the effect of exercise and also
  • 01:41 --> 01:43sometimes the role of weight management
  • 01:43 --> 01:46and nutrition on various cancer outcomes.
  • 01:46 --> 01:49We've looked at this in breast cancer
  • 01:49 --> 01:51and other cancers really trying to
  • 01:51 --> 01:53figure out the role of exercise in
  • 01:53 --> 01:55mechanisms for improving prognosis,
  • 01:55 --> 01:59but also its role in patient reported
  • 01:59 --> 02:02outcomes and how exercise can improve that.
  • 02:02 --> 02:05And much of the research that we
  • 02:05 --> 02:07and others have done has informed
  • 02:07 --> 02:09guidelines that are now making its way
  • 02:09 --> 02:11into standard of care for treatment.
  • 02:12 --> 02:14And so to that point, Tara,
  • 02:14 --> 02:17can you talk a little bit about the
  • 02:17 --> 02:18role that exercise plays in the
  • 02:18 --> 02:20treatment and management
  • 02:20 --> 02:22of patients with breast cancer?
  • 02:24 --> 02:29Sure. You know exercise has been
  • 02:29 --> 02:32shown to improve many outcomes in
  • 02:32 --> 02:35survivorship and even during
  • 02:35 --> 02:37treatment there's very strong
  • 02:37 --> 02:39data that suggests that exercise
  • 02:39 --> 02:41improves cancer related fatigue,
  • 02:42 --> 02:44reduces anxiety and depression,
  • 02:44 --> 02:47improves sleep quality and helps
  • 02:47 --> 02:48patients maintain function
  • 02:48 --> 02:51both during and after treatment.
  • 02:51 --> 02:54There's also data that's emerged that
  • 02:54 --> 02:57shows that patients who have more
  • 02:57 --> 02:59physical activity in their life may
  • 02:59 --> 03:01have better long term outcomes in terms
  • 03:01 --> 03:03of reduced breast cancer recurrence
  • 03:03 --> 03:06and better overall survival.
  • 03:07 --> 03:09And I might just add to that,
  • 03:09 --> 03:11what's really exciting is the
  • 03:11 --> 03:13research that we and many others
  • 03:13 --> 03:16have done has really shown that
  • 03:16 --> 03:18even little bits of exercise or
  • 03:18 --> 03:21physical activity can have an impact.
  • 03:21 --> 03:25So it's not necessarily you know,
  • 03:25 --> 03:27high levels or high intensities or high
  • 03:27 --> 03:29amounts of exercise that are required,
  • 03:29 --> 03:31but it's pretty compelling evidence that
  • 03:31 --> 03:33doing something is better than nothing.
  • 03:33 --> 03:36So even if it's
  • 03:36 --> 03:38the recommended amount of physical
  • 03:38 --> 03:40activity, 2 1/2 hours per week,
  • 03:40 --> 03:41but there's evidence showing
  • 03:41 --> 03:44that even less than that amount
  • 03:44 --> 03:45is beneficial for outcomes.
  • 03:47 --> 03:50And so when should
  • 03:50 --> 03:52patients really start exercising?
  • 03:54 --> 03:57I think that when people are initially
  • 03:57 --> 03:59diagnosed with breast cancer,
  • 03:59 --> 04:00their first concept is,
  • 04:00 --> 04:04oh my God, I've got breast cancer,
  • 04:04 --> 04:06not let me see what I can
  • 04:06 --> 04:07do to increase my exercise.
  • 04:07 --> 04:10So can you talk a little bit about
  • 04:10 --> 04:14when people should start integrating
  • 04:14 --> 04:17more exercise into their lives?
  • 04:17 --> 04:18Ideally it should be before
  • 04:18 --> 04:20they ever get breast cancer.
  • 04:20 --> 04:23But how do you have that conversation
  • 04:23 --> 04:26with people and start getting
  • 04:26 --> 04:29exercise into the
  • 04:29 --> 04:31treatment algorithm if you would
  • 04:31 --> 04:33for people with breast cancer?
  • 04:34 --> 04:36Yeah, thanks for asking that.
  • 04:36 --> 04:39I find this to be one of the
  • 04:39 --> 04:42most compelling times in medical care
  • 04:42 --> 04:46which is soon after diagnosis.
  • 04:46 --> 04:49It's unusual for us as adults to
  • 04:49 --> 04:52really make major life changes sometimes
  • 04:52 --> 04:55until we have a teachable moment.
  • 04:55 --> 04:57An example is maybe becoming pregnant for
  • 04:57 --> 05:01the first time or having a heart attack
  • 05:01 --> 05:03for instance and cancer is one of
  • 05:03 --> 05:06those times when as adults we tend to be
  • 05:06 --> 05:09open and motivated to make major changes.
  • 05:09 --> 05:11So first of all we should
  • 05:11 --> 05:13all be exercising, all of us.
  • 05:13 --> 05:14But we know that the vast majority
  • 05:14 --> 05:16of us do not meet the recommended
  • 05:16 --> 05:18guidelines of 2 1/2 hours per week.
  • 05:18 --> 05:19And as Melinda said,
  • 05:19 --> 05:21something is better than nothing.
  • 05:21 --> 05:23But a lot of people are not
  • 05:23 --> 05:25meeting even close to that.
  • 05:25 --> 05:28So soon after diagnosis is this teachable
  • 05:28 --> 05:31moment where we can start to help our
  • 05:31 --> 05:33patients become a part of their care
  • 05:33 --> 05:36by giving them more control over what
  • 05:36 --> 05:38they're doing between visits,
  • 05:38 --> 05:41at home, by moving a little bit more.
  • 05:41 --> 05:42That being said,
  • 05:42 --> 05:44there are a significant number
  • 05:44 --> 05:47of patients who are overwhelmed with
  • 05:47 --> 05:48the diagnosis process,
  • 05:48 --> 05:49understandably.
  • 05:49 --> 05:51And certainly we don't want to shame
  • 05:51 --> 05:54people for not being able to adopt
  • 05:54 --> 05:56these healthy behaviors right away.
  • 05:57 --> 05:59That's where survivorship comes in after
  • 05:59 --> 06:00treatment to really encourage
  • 06:00 --> 06:02patients at that point to start to
  • 06:02 --> 06:04rethink their approach and maybe
  • 06:04 --> 06:06tweak what they're doing a little
  • 06:06 --> 06:09bit to optimize their health after
  • 06:09 --> 06:12treatment anywhere along the spectrum.
  • 06:12 --> 06:14We want to encourage patients
  • 06:14 --> 06:16do this because it has so many
  • 06:16 --> 06:18upsides and very few downsides.
  • 06:18 --> 06:20And Melinda, maybe you can
  • 06:20 --> 06:22talk a little bit about some of
  • 06:22 --> 06:24the trials that you've done
  • 06:24 --> 06:26and shed a bit of light into the research.
  • 06:26 --> 06:28Has the research been done more in the
  • 06:32 --> 06:35survivorship period when people are
  • 06:35 --> 06:37going through chemotherapy afterwards?
  • 06:37 --> 06:39And talk a little bit about
  • 06:39 --> 06:43kind of where this little bit is better,
  • 06:43 --> 06:45something is better than nothing
  • 06:45 --> 06:47comes in and whether there's
  • 06:47 --> 06:49a minimum.
  • 06:49 --> 06:52If I exercise only 10 minutes,
  • 06:52 --> 06:53is that good enough?
  • 06:53 --> 06:55Can you talk a little bit about the
  • 06:55 --> 06:57research that's been done in this area?
  • 06:58 --> 07:01Sure, yes. So for probably
  • 07:01 --> 07:03a good 10 or so years,
  • 07:03 --> 07:05most of the research looking at
  • 07:05 --> 07:07exercise after cancer diagnosis has
  • 07:07 --> 07:09been in the post treatment setting.
  • 07:09 --> 07:13So after chemotherapy and radiation
  • 07:13 --> 07:17treatment looking at how exercise might
  • 07:17 --> 07:19improve patient reported outcomes,
  • 07:19 --> 07:23sleep, quality of life, fatigue.
  • 07:23 --> 07:24And from the research that Tara
  • 07:24 --> 07:26and I have done as well as many
  • 07:26 --> 07:28others, has shown that some patients,
  • 07:28 --> 07:31not all but some patients, when they
  • 07:31 --> 07:33hear of the benefits of exercise in
  • 07:33 --> 07:36that post treatment time setting and
  • 07:36 --> 07:37they hear of potential benefits that
  • 07:37 --> 07:39it could have had during treatment,
  • 07:40 --> 07:42they ask, why didn't I receive this
  • 07:42 --> 07:44information sooner at diagnosis?
  • 07:44 --> 07:45And so as Tara suggested,
  • 07:45 --> 07:48some people do want that information
  • 07:48 --> 07:51earlier and assistance in adding
  • 07:51 --> 07:54exercise into their routine during treatment.
  • 07:54 --> 07:57And so Tara and I actually led a
  • 07:57 --> 07:59trial together that just completed and
  • 07:59 --> 08:02was recently published that was an
  • 08:02 --> 08:03exercise and nutrition intervention
  • 08:03 --> 08:06during chemotherapy for breast cancer.
  • 08:06 --> 08:08And when we say exercise,
  • 08:08 --> 08:10what we mean is we prescribe
  • 08:10 --> 08:12for these women primarily a brisk
  • 08:12 --> 08:14walking program that could be done
  • 08:14 --> 08:16at their home, in their neighborhood,
  • 08:16 --> 08:20as well as we developed a home based
  • 08:20 --> 08:22resistance strength training
  • 08:22 --> 08:24program in their home, and
  • 08:24 --> 08:26we create creative material to help
  • 08:26 --> 08:29them figure out which exercises to do.
  • 08:29 --> 08:31And the importance of initiating this
  • 08:31 --> 08:33during treatment is to maintain or
  • 08:33 --> 08:36even maybe increase a bit your muscle
  • 08:36 --> 08:38mass because we know that muscle
  • 08:38 --> 08:40is important for various outcomes
  • 08:40 --> 08:42and there could be adverse effects
  • 08:42 --> 08:44of chemotherapy on muscle.
  • 08:44 --> 08:46So the idea of exercising either
  • 08:46 --> 08:48with just brisk walking which is
  • 08:48 --> 08:50a weight bearing activity during
  • 08:50 --> 08:52treatment to maintain muscle mass,
  • 08:52 --> 08:55but if not then in the post treatment
  • 08:55 --> 08:57setting helping to improve other outcomes
  • 08:57 --> 08:59is really important to think about.
  • 08:59 --> 09:01And one of the approaches we had
  • 09:01 --> 09:03our study participants consider is
  • 09:03 --> 09:06that shortly after diagnosis
  • 09:06 --> 09:08friends and family and neighbors
  • 09:08 --> 09:10want to help out and often
  • 09:10 --> 09:12bringing over meals or whatnot.
  • 09:12 --> 09:15And so we recommended that if there
  • 09:15 --> 09:17was an opportunity for them to set up
  • 09:17 --> 09:19a time each week to walk with someone,
  • 09:19 --> 09:20a neighbor or a friend,
  • 09:20 --> 09:22that might be helpful as well.
  • 09:22 --> 09:23And you know,
  • 09:23 --> 09:25these walks could be for 10
  • 09:25 --> 09:28minutes or 30 minutes depending on the
  • 09:28 --> 09:30individual's ability and how they feel,
  • 09:30 --> 09:32how many days post chemotherapy it might be.
  • 09:32 --> 09:34We know that those couple
  • 09:34 --> 09:35days post chemo are a little bit
  • 09:35 --> 09:37more challenging than say the week
  • 09:37 --> 09:38or two thereafter.
  • 09:39 --> 09:43I love the idea of
  • 09:43 --> 09:46instead of bringing over a cake
  • 09:46 --> 09:49to offer to walk with somebody,
  • 09:49 --> 09:52it might actually be just as good
  • 09:52 --> 09:56for their heart and soul and
  • 09:56 --> 09:58might actually be helpful in their
  • 09:58 --> 10:00survivorship journey.
  • 10:03 --> 10:05Tara, Melinda had mentioned resistance training
  • 10:05 --> 10:08and walking. Is one better than the other?
  • 10:08 --> 10:10Do you prescribe both to your patients?
  • 10:10 --> 10:12How much of each?
  • 10:12 --> 10:14What should patients be aware of?
  • 10:15 --> 10:17Yeah, and I'll welcome
  • 10:17 --> 10:19Melinda to chime in, too.
  • 10:19 --> 10:22But you know, I have to say for a
  • 10:22 --> 10:24long time the only thing I was really
  • 10:24 --> 10:26recommending to my patients was walking.
  • 10:26 --> 10:29And that's a lot because of the
  • 10:29 --> 10:31trials leading into our most recent
  • 10:31 --> 10:34study showed the benefits of walking.
  • 10:34 --> 10:36It's free for most people.
  • 10:36 --> 10:37If you have a safe place,
  • 10:37 --> 10:39you can do it right out of your home.
  • 10:39 --> 10:42I have to say that the evidence is
  • 10:42 --> 10:44emerging that also strength training
  • 10:44 --> 10:47is extremely beneficial and I
  • 10:47 --> 10:49feel like it's been undervalued
  • 10:49 --> 10:53socially because at least in the
  • 10:53 --> 10:54female population that I take care of,
  • 10:54 --> 10:56very few women are strength
  • 10:56 --> 10:58training on a routine basis.
  • 11:00 --> 11:01I think it points towards
  • 11:01 --> 11:03easier treatment completion.
  • 11:03 --> 11:05There's some data that suggests
  • 11:05 --> 11:07that when strength training is added,
  • 11:07 --> 11:09so cardiovascular and strength
  • 11:09 --> 11:11training are both two parts
  • 11:11 --> 11:14of a Ying and a Yang to
  • 11:14 --> 11:16exercise that I think we need to
  • 11:16 --> 11:18really be enforcing both of them.
  • 11:18 --> 11:18And Melinda,
  • 11:18 --> 11:21I'd love to hear your opinion on that.
  • 11:21 --> 11:22Yeah, I agree with that.
  • 11:22 --> 11:24I mean first and foremost if we
  • 11:24 --> 11:27just get people going from not
  • 11:27 --> 11:29very much to doing something and
  • 11:29 --> 11:31if they choose walking and are
  • 11:31 --> 11:33not able to or they're not really
  • 11:33 --> 11:34enjoying the strength training,
  • 11:34 --> 11:35then that's better than not
  • 11:35 --> 11:37doing either or vice versa.
  • 11:37 --> 11:39We have found that some of our
  • 11:39 --> 11:40participants have really appreciated
  • 11:40 --> 11:43the home based strength training program
  • 11:43 --> 11:45and that was easier for them to do
  • 11:45 --> 11:47than to get outside and go walking.
  • 11:47 --> 11:50And the nice thing is nowadays if
  • 11:50 --> 11:52someone has an iPhone or an iPad,
  • 11:52 --> 11:54there's so many apps that they
  • 11:54 --> 11:57can download for free that do
  • 11:57 --> 11:58a different daily workout.
  • 11:59 --> 12:01Whether it be a Pilates or a
  • 12:01 --> 12:02resistance strength training program,
  • 12:02 --> 12:05we've developed one as well for participants.
  • 12:07 --> 12:10But I encourage walking and or strength
  • 12:10 --> 12:12training and while both are fantastic,
  • 12:12 --> 12:15just doing something that really
  • 12:15 --> 12:17makes them feel good and it's
  • 12:17 --> 12:18easier for them to initiate is
  • 12:18 --> 12:20probably a good place to start.
  • 12:21 --> 12:24And one of the things that you
  • 12:24 --> 12:27mentioned was that it's free and
  • 12:27 --> 12:30doesn't really require a lot of equipment.
  • 12:30 --> 12:32So even the strength training, Tara,
  • 12:32 --> 12:35can you talk a little
  • 12:35 --> 12:38bit about what you are advocating?
  • 12:38 --> 12:40I mean some people when they hear
  • 12:40 --> 12:42strength training, they think, jeez,
  • 12:42 --> 12:43I'm going to need to go to the gym.
  • 12:43 --> 12:45I'm going to need to
  • 12:45 --> 12:47pick up heavy weights,
  • 12:47 --> 12:49but other people might say,
  • 12:49 --> 12:51you know, what if I have a couple
  • 12:51 --> 12:53of jugs of laundry detergent,
  • 12:53 --> 12:55I can do a bit of strength
  • 12:55 --> 12:56training in my own home.
  • 12:56 --> 12:58Can you talk a little bit about that?
  • 12:59 --> 13:01Yeah, you're reminding me that I used to
  • 13:01 --> 13:03tell my 80 year old grandmother to just
  • 13:03 --> 13:07you know, bicep curl a soup can
  • 13:07 --> 13:09because she wasn't doing
  • 13:09 --> 13:12anything and she would do this in
  • 13:12 --> 13:14her kitchen while she was cooking.
  • 13:14 --> 13:16I think we overlook
  • 13:16 --> 13:19body weight strength training, right?
  • 13:19 --> 13:23So there are simple moves that can
  • 13:23 --> 13:26place a load on certain parts of your
  • 13:26 --> 13:30body like a plank or a squat that
  • 13:30 --> 13:33again requires no equipment at all.
  • 13:33 --> 13:35And there's also resistance bands
  • 13:35 --> 13:38that you can buy on the Internet or
  • 13:38 --> 13:40or at your local department stores.
  • 13:40 --> 13:43And those also provide
  • 13:43 --> 13:45some just natural resistance that
  • 13:45 --> 13:48don't require massive number of
  • 13:48 --> 13:49weights and dumbbells.
  • 13:49 --> 13:52I think we're really evolving with
  • 13:52 --> 13:54how we talk about strength training.
  • 13:54 --> 13:56It's no longer just beefing up
  • 13:56 --> 13:57to get big muscles.
  • 13:57 --> 13:58Well, that's great information.
  • 13:58 --> 14:01We are going to take a short
  • 14:01 --> 14:02break for a medical minute.
  • 14:02 --> 14:04Please stay tuned to learn
  • 14:04 --> 14:05more about exercise and breast
  • 14:05 --> 14:07cancer with my guests Dr.
  • 14:07 --> 14:09Tara Sanft and Melinda Irwin.
  • 14:10 --> 14:12Funding for Yale Cancer Answers
  • 14:12 --> 14:14comes from Smilow Cancer Hospital,
  • 14:14 --> 14:16where spiritual care offers support
  • 14:16 --> 14:18to patients seeking peace in the
  • 14:18 --> 14:19midst of their cancer journey,
  • 14:19 --> 14:21while respecting the unique
  • 14:21 --> 14:22philosophies, spiritualities,
  • 14:22 --> 14:25and religions of patients and caregivers.
  • 14:25 --> 14:28Smilowcancerhospital.org.
  • 14:30 --> 14:32The American Cancer Society
  • 14:32 --> 14:34estimates that more than 65,000
  • 14:34 --> 14:36Americans will be diagnosed with
  • 14:36 --> 14:38head and neck cancer this year,
  • 14:38 --> 14:41making up about 4% of all cancers
  • 14:41 --> 14:43diagnosed. When detected early,
  • 14:43 --> 14:45however, head and neck cancers are
  • 14:45 --> 14:47easily treated and highly curable.
  • 14:47 --> 14:49Clinical trials are currently
  • 14:49 --> 14:51underway at federally designated
  • 14:51 --> 14:53Comprehensive Cancer Centers,
  • 14:53 --> 14:56such as Yale Cancer Center and Smilow
  • 14:56 --> 14:58Cancer Hospital to test innovative new
  • 14:58 --> 15:01treatments for head and neck cancers.
  • 15:01 --> 15:03Yale Cancer Center was recently
  • 15:03 --> 15:04awarded grants from the National
  • 15:04 --> 15:07Institutes of Health to fund the
  • 15:07 --> 15:09Yale Head and Neck Cancer Specialized
  • 15:09 --> 15:11Program of Research Excellence,
  • 15:11 --> 15:12or SPORE,
  • 15:12 --> 15:14to address critical barriers to
  • 15:14 --> 15:17treatment of head and neck squamous cell
  • 15:17 --> 15:19carcinoma due to resistance to immune
  • 15:19 --> 15:22DNA damaging and targeted therapy.
  • 15:22 --> 15:24More information is available
  • 15:24 --> 15:25at yalecancercenter.org.
  • 15:25 --> 15:28You're listening to Connecticut Public Radio.
  • 15:29 --> 15:31Welcome back to Yale Cancer Answers.
  • 15:31 --> 15:33This is Doctor Anees Chagpar and
  • 15:33 --> 15:35I'm joined tonight by my guests, Dr.
  • 15:35 --> 15:37Tara Sanft and Melinda Irwin.
  • 15:37 --> 15:40We're talking about exercise as a standard
  • 15:40 --> 15:42of care for women with breast cancer.
  • 15:42 --> 15:43Now before the break,
  • 15:43 --> 15:46we were talking about the value of
  • 15:46 --> 15:48exercise and how there have been a
  • 15:48 --> 15:50number of studies that have demonstrated
  • 15:50 --> 15:53that it improves quality of life,
  • 15:53 --> 15:57it can improve chemotherapy completion rates.
  • 15:57 --> 15:59Overall, it's just good for us.
  • 15:59 --> 16:01And so Tara, maybe you can talk
  • 16:01 --> 16:04a little bit about how it is now
  • 16:04 --> 16:06becoming a standard of care.
  • 16:07 --> 16:11I'm so excited to see exercise
  • 16:11 --> 16:15become a part of the treatment plan.
  • 16:15 --> 16:17And you know, one way that we see this
  • 16:17 --> 16:20is in program standards as you mentioned.
  • 16:20 --> 16:23And the national accreditation
  • 16:23 --> 16:26program for breast centers is one
  • 16:26 --> 16:29of those programs that's been in
  • 16:29 --> 16:30existence for quite some time.
  • 16:30 --> 16:33And their goal is really
  • 16:33 --> 16:36to make sure that NAPBC accredited
  • 16:36 --> 16:39programs are offering all the components
  • 16:39 --> 16:42of care that make care excellent.
  • 16:42 --> 16:45And recently they've just revamped
  • 16:45 --> 16:46their standards.
  • 16:46 --> 16:48And I'm just going to read one of
  • 16:48 --> 16:50the lines from the standard and to
  • 16:50 --> 16:52me this as a patient experience
  • 16:52 --> 16:54officer speaks volumes.
  • 16:54 --> 16:57They say that patients must be viewed
  • 16:57 --> 17:02in the context of their entire personhood.
  • 17:02 --> 17:05And I just think that is what we
  • 17:05 --> 17:06should all be doing across medicine.
  • 17:06 --> 17:09And I love to see that in writing
  • 17:09 --> 17:11and part of that personhood
  • 17:11 --> 17:13includes how someone is functioning.
  • 17:13 --> 17:16So really starting at diagnosis and
  • 17:16 --> 17:17spanning throughout the treatment
  • 17:17 --> 17:19trajectory and into survivorship.
  • 17:19 --> 17:22All patients must be considered
  • 17:22 --> 17:24for functional assessment and
  • 17:24 --> 17:27the program standards want to see
  • 17:27 --> 17:29documentation of exercise therapy
  • 17:29 --> 17:30recommendations.
  • 17:31 --> 17:33Melinda, I want to go back to you.
  • 17:33 --> 17:35What are the recommendations
  • 17:35 --> 17:38that based on the evidence
  • 17:38 --> 17:39doctors should be suggesting?
  • 17:39 --> 17:41I mean, we talked about the 2 1/2
  • 17:41 --> 17:43hours being the current guidelines but
  • 17:43 --> 17:46something being better than nothing.
  • 17:46 --> 17:48Can you talk a little bit about,
  • 17:48 --> 17:52you know what you would suggest as
  • 17:52 --> 17:54an initial recommendation both from
  • 17:54 --> 17:56the walking standpoint as well as
  • 17:56 --> 17:59from a strength training standpoint,
  • 17:59 --> 18:01where should patients
  • 18:01 --> 18:03and doctors start?
  • 18:03 --> 18:04I'd like to just first
  • 18:04 --> 18:06make two quick comments.
  • 18:06 --> 18:08I really appreciate what Tara just
  • 18:08 --> 18:10read and the importance of
  • 18:10 --> 18:13focusing on the whole person.
  • 18:13 --> 18:14And I'm reminded of one
  • 18:14 --> 18:16of our study participants.
  • 18:16 --> 18:18In fact, there were many study
  • 18:18 --> 18:20participants in our trial that was
  • 18:20 --> 18:22of exercise during chemotherapy where
  • 18:22 --> 18:25these women reported at the end of
  • 18:25 --> 18:27the intervention which was at the
  • 18:27 --> 18:28end of their chemotherapy that they
  • 18:28 --> 18:32felt stronger and physically more fit
  • 18:32 --> 18:36at the end of chemotherapy than before.
  • 18:36 --> 18:38And the program we offered them was
  • 18:38 --> 18:40a primarily brisk walking upwards
  • 18:40 --> 18:43of 2 1/2 hours per week and twice a
  • 18:43 --> 18:46week the at home resistance
  • 18:46 --> 18:47strength training program with
  • 18:47 --> 18:50dumbbells that were 2 lbs and 5
  • 18:50 --> 18:53lbs and also resistance bands.
  • 18:53 --> 18:56The other thing to note is that exercise
  • 18:56 --> 18:59has benefits also for other outcomes
  • 18:59 --> 19:01including cardiovascular disease and
  • 19:01 --> 19:04hypertension and cholesterol and diabetes.
  • 19:04 --> 19:06So while it's improving cancer outcomes,
  • 19:06 --> 19:08it's also improving other outcomes
  • 19:08 --> 19:10we know that are important
  • 19:10 --> 19:12to patients with breast cancer.
  • 19:12 --> 19:14I also think it's important that
  • 19:14 --> 19:17the research and the focus shift
  • 19:17 --> 19:21on helping providers be able
  • 19:21 --> 19:24to not just recommend exercise,
  • 19:24 --> 19:26but who to refer them to.
  • 19:26 --> 19:27There's survivorship clinics
  • 19:27 --> 19:30and programs at cancer centers,
  • 19:30 --> 19:32cancer hospitals and community
  • 19:32 --> 19:33based organizations.
  • 19:33 --> 19:35So it's important that we
  • 19:35 --> 19:36just don't recommend it,
  • 19:37 --> 19:39but we follow up with who to refer
  • 19:39 --> 19:43them to and are writing them a
  • 19:43 --> 19:45prescription that meets
  • 19:46 --> 19:48what they're able to do in their
  • 19:48 --> 19:49neighborhood or in their home.
  • 19:49 --> 19:52If they just leave being told to walk
  • 19:52 --> 19:54more and maybe do some resistance training,
  • 19:54 --> 19:57that's probably a little bit more
  • 19:57 --> 19:58challenging for the patient to
  • 19:58 --> 20:01understand how much when and where.
  • 20:01 --> 20:03So if we can get even more specific
  • 20:03 --> 20:05with the referral process and or
  • 20:05 --> 20:08writing a prescription that would be
  • 20:08 --> 20:10really important to take these standards of
  • 20:10 --> 20:12incorporating physical
  • 20:12 --> 20:13activity into clinical care.
  • 20:13 --> 20:16And one of the things,
  • 20:17 --> 20:19Tara, in the studies,
  • 20:19 --> 20:22there was somebody kind of
  • 20:22 --> 20:24presumably checking in on these patients.
  • 20:24 --> 20:25How are you doing?
  • 20:25 --> 20:28Did you do your walking?
  • 20:28 --> 20:32What are the resources available to
  • 20:32 --> 20:35patients in the community in terms
  • 20:35 --> 20:38of having someone check in on them
  • 20:38 --> 20:40and provide this kind of ongoing
  • 20:40 --> 20:43support in terms of their exercise?
  • 20:43 --> 20:45I'm glad you asked this.
  • 20:46 --> 20:49I do want to mention that
  • 20:49 --> 20:51in addition to prescribing let's say
  • 20:51 --> 20:54a walking program or again if
  • 20:54 --> 20:57there's something you like to do
  • 20:57 --> 21:00because that's the best form of exercise.
  • 21:00 --> 21:04There is also a movement towards more
  • 21:04 --> 21:07formal assessments and prescriptions
  • 21:07 --> 21:08through professionally trained
  • 21:08 --> 21:10physical therapists for instance.
  • 21:10 --> 21:13And many places label this
  • 21:13 --> 21:15an oncology rehab program.
  • 21:15 --> 21:18And often if it's instilled sort of at
  • 21:18 --> 21:20diagnosis before all your treatments
  • 21:20 --> 21:23get started, we call it prehab.
  • 21:23 --> 21:27So rehab and prehab and for extensive
  • 21:27 --> 21:30surgeries or extensive treatments or
  • 21:30 --> 21:34an individual who has a lot of
  • 21:34 --> 21:36issues going on that may impact their
  • 21:36 --> 21:39safety as it relates to exercise,
  • 21:39 --> 21:42a physical therapist or an ANC rehab
  • 21:42 --> 21:45program is definitely the way to go.
  • 21:45 --> 21:47And again not every place is fortunate
  • 21:47 --> 21:49to enjoy these resources,
  • 21:49 --> 21:51but I think putting them into the
  • 21:51 --> 21:54standards will ensure that institutions
  • 21:54 --> 21:57who want to be accredited will spend
  • 21:57 --> 21:59more investment in getting
  • 21:59 --> 22:01these programs up and running.
  • 22:01 --> 22:03In terms of the coaching
  • 22:03 --> 22:05or having someone check in,
  • 22:05 --> 22:07we had our trained interventionist
  • 22:07 --> 22:09check in with the patients 11
  • 22:09 --> 22:12times over the course of the year.
  • 22:12 --> 22:15So again it wasn't a daily check in process.
  • 22:15 --> 22:17It was more intense at
  • 22:17 --> 22:19the beginning and then spaced out
  • 22:19 --> 22:21over the following months.
  • 22:21 --> 22:24There are other wonderful community programs.
  • 22:24 --> 22:26One that comes to mind that my patients
  • 22:26 --> 22:29love is the LIVESTRONG program,
  • 22:29 --> 22:31which is a national program offered
  • 22:31 --> 22:35at many YMCAS that is specific to
  • 22:35 --> 22:38cancer patients and the programming
  • 22:38 --> 22:39allows for more of a community feel.
  • 22:39 --> 22:41So if you like to exercise with
  • 22:41 --> 22:43a group of people who have been
  • 22:43 --> 22:45through something that is
  • 22:45 --> 22:47not exactly your experience,
  • 22:47 --> 22:49but maybe close to it because of
  • 22:49 --> 22:51the common thread of being a
  • 22:51 --> 22:53cancer patient or a cancer survivor,
  • 22:53 --> 22:55this is really something that I
  • 22:55 --> 22:57encourage people to take advantage of.
  • 22:57 --> 22:59And then of course,
  • 22:59 --> 23:01there's other supervised programs at,
  • 23:01 --> 23:02you know,
  • 23:02 --> 23:04community centers and things where
  • 23:04 --> 23:07you can do not as intense exercise maybe,
  • 23:07 --> 23:10but also build a community and whatever
  • 23:10 --> 23:12exercise that feels right for you.
  • 23:13 --> 23:15Yeah, Melinda, I'm just thinking
  • 23:15 --> 23:18about people who may be listening
  • 23:18 --> 23:20to this and thinking, you know,
  • 23:20 --> 23:23I was diagnosed whatever last year,
  • 23:23 --> 23:27last month, a decade ago, and wasn't
  • 23:27 --> 23:29really provided this recommendation.
  • 23:29 --> 23:33But in hearing about the benefits of
  • 23:33 --> 23:36exercise, it may be helpful for me to start,
  • 23:36 --> 23:39even though I didn't start at the
  • 23:39 --> 23:41time of diagnosis. Two questions, first,
  • 23:41 --> 23:45is it still valuable to start a week,
  • 23:45 --> 23:48a month, a decade after diagnosis?
  • 23:48 --> 23:51And 2nd, where can people get resources
  • 23:51 --> 23:54if they're finished their cancer journey,
  • 23:54 --> 23:56at least their acute cancer journey?
  • 23:56 --> 24:00Are the recommendations that you had
  • 24:00 --> 24:03provided to patients available in
  • 24:03 --> 24:07an online accessible kind of
  • 24:07 --> 24:10platform where survivors can access that?
  • 24:11 --> 24:12Yeah, really important questions.
  • 24:12 --> 24:13And I would say yes,
  • 24:13 --> 24:16it's never too late to start a
  • 24:16 --> 24:18program whether they were diagnosed
  • 24:18 --> 24:21yesterday or 10-20 years ago.
  • 24:21 --> 24:25I would say the the first stop could
  • 24:25 --> 24:28be outreach to if they're still
  • 24:28 --> 24:29regularly seeing their oncologist
  • 24:29 --> 24:32reaching out to them or to their
  • 24:32 --> 24:35primary care doctor and asking them
  • 24:35 --> 24:38about resources that might be available
  • 24:38 --> 24:40at the hospital or in the community.
  • 24:40 --> 24:43They might have documents available that
  • 24:43 --> 24:46list resources if they're just diagnosed
  • 24:46 --> 24:49or just recently completing treatment.
  • 24:49 --> 24:53I would like to see hospitals think about
  • 24:53 --> 24:55their cardiovascular rehab programs,
  • 24:55 --> 24:58cardiac rehab programs that are
  • 24:58 --> 25:00available and thinking about how to
  • 25:00 --> 25:02share resources either to broaden it
  • 25:02 --> 25:06to include a cancer rehab program.
  • 25:06 --> 25:08And many times those are offered
  • 25:08 --> 25:10at least cardiac rehab is offered
  • 25:10 --> 25:12right after a cardiovascular event
  • 25:12 --> 25:14and maybe not years later.
  • 25:14 --> 25:18But I know for example survivorship programs,
  • 25:18 --> 25:20they might see patients anytime
  • 25:20 --> 25:22after diagnosis upward to 10-20
  • 25:22 --> 25:23years after diagnosis.
  • 25:23 --> 25:26And so that's a really good first
  • 25:26 --> 25:29stop as well to to reach out
  • 25:29 --> 25:30to those survivorship programs.
  • 25:30 --> 25:33Also Tara mentioned the YMCA and
  • 25:33 --> 25:35the Livestrong program.
  • 25:35 --> 25:38Many YMCA's also offer related programs,
  • 25:38 --> 25:40not necessarily specific to cancer,
  • 25:40 --> 25:42but for example,
  • 25:42 --> 25:45the Diabetes Prevention program is
  • 25:45 --> 25:47open that focuses on exercise and nutrition.
  • 25:47 --> 25:49Those are at YMCA's there's
  • 25:49 --> 25:51programs called the Silver Sneakers
  • 25:51 --> 25:53Exercise programs at the Y.
  • 25:53 --> 25:56For people of a certain age,
  • 25:56 --> 25:58Medicare reimburses programs that
  • 25:58 --> 26:01are more weight management focused
  • 26:01 --> 26:03that includes exercise.
  • 26:03 --> 26:05So definitely talking to the primary
  • 26:05 --> 26:07care physician and the oncologist
  • 26:07 --> 26:09can provide some information
  • 26:09 --> 26:11and is a good starting point.
  • 26:14 --> 26:15If I could add into that,
  • 26:15 --> 26:18you know we do see patients long
  • 26:18 --> 26:21after treatment has ended in our
  • 26:21 --> 26:23multidisciplinary clinic and
  • 26:23 --> 26:25we always reminisce or say that
  • 26:25 --> 26:27patients find us when they need us
  • 26:27 --> 26:29and then our other mantra is
  • 26:29 --> 26:31that we meet them where they're at.
  • 26:31 --> 26:33So you know there are people who used
  • 26:33 --> 26:35to run marathons and then maybe had
  • 26:35 --> 26:37extensive cancer treatment and thought,
  • 26:37 --> 26:39I don't think I could ever do that again.
  • 26:39 --> 26:41But eventually they want to
  • 26:41 --> 26:43know if they could and so you know
  • 26:43 --> 26:46I think it's never too late to
  • 26:46 --> 26:48reevaluate goals and hopes
  • 26:48 --> 26:51and dreams and that can come
  • 26:51 --> 26:52anytime after cancer treatment.
  • 26:54 --> 26:58Yeah. One of the questions
  • 26:58 --> 27:01that I'm thinking about is that
  • 27:01 --> 27:03there must be some barriers right
  • 27:03 --> 27:05to getting patients to exercise.
  • 27:05 --> 27:08One might be I'm too tired.
  • 27:08 --> 27:11One might be I don't have enough time.
  • 27:11 --> 27:13One might be I'm too stressed out.
  • 27:13 --> 27:17How do you counsel patients
  • 27:17 --> 27:22about getting over those barriers, Tara?
  • 27:23 --> 27:25Yeah, I think these are
  • 27:25 --> 27:28really good points and so true.
  • 27:30 --> 27:33Our culture, our work culture in this
  • 27:33 --> 27:36country is one of exhaustion, time limited
  • 27:36 --> 27:39resources and a lot of stress.
  • 27:39 --> 27:41So I think validating that is
  • 27:41 --> 27:43really important.
  • 27:43 --> 27:47And then we try to encourage
  • 27:47 --> 27:50patients that whatever they're doing,
  • 27:50 --> 27:53is there a way to do a little bit
  • 27:53 --> 27:56more or to make certain trade-offs so
  • 27:56 --> 27:58that you're still meeting your goals?
  • 27:58 --> 28:02You know, and I've had the privilege of
  • 28:02 --> 28:04working with the physical therapist who does
  • 28:04 --> 28:06all of our exercise counseling and you know,
  • 28:06 --> 28:09he has a little tip sheet on ways
  • 28:09 --> 28:11to get in a little bit more movement.
  • 28:11 --> 28:13And I think everyone
  • 28:13 --> 28:15understands the concept of parking
  • 28:15 --> 28:17in the furthest away parking spot.
  • 28:17 --> 28:19But that counts and
  • 28:19 --> 28:20are we doing that?
  • 28:20 --> 28:22I would love to see the stairways,
  • 28:22 --> 28:23even in our hospitals,
  • 28:23 --> 28:25be the central focus
  • 28:25 --> 28:27rather than the elevator banks.
  • 28:27 --> 28:30Doctor Tara Sanft is an associate professor
  • 28:30 --> 28:33of Medicine and Medical oncology, and Dr.
  • 28:33 --> 28:35Melinda Irwin is the Susan Dwight
  • 28:35 --> 28:36Bliss Professor of Epidemiology
  • 28:36 --> 28:38at the Yale School of Medicine.
  • 28:38 --> 28:40If you have questions,
  • 28:40 --> 28:42the address is canceranswers@yale.edu,
  • 28:42 --> 28:45and past additions of the program
  • 28:45 --> 28:47are available in audio and written
  • 28:47 --> 28:48form at yalecancercenter.org.
  • 28:48 --> 28:51We hope you'll join us next week to
  • 28:51 --> 28:53learn more about the fight against
  • 28:53 --> 28:54cancer here on Connecticut Public Radio.
  • 28:54 --> 28:57Funding for Yale Cancer Answers is
  • 28:57 --> 29:00provided by Smilow Cancer Hospital.