Screening In Anticipation of Future Research

This screening protocol proposes to test blood samples for HIV, hepatitis B and hepatitis C infection status of patients consenting to participate in the Yale Liver Center Patient Registry and Serum/Tissue Bank (HIC protocol # 0603001208). Subjects are selected for having or being at risk for rare liver disease or liver disorder genetically caused (e.g., cystic fibrosis) or involving altered immunity or for their willingness to serve as healthy controls. 

The Yale Liver Center Patient Registry and Specimen Bank is hereafter referred to as the Registry and Bank.

Healthy adults to act as controls (comparison to others who do have a medical issue). Also, children 2 to 17 years old and adults who are at risk of or have any of the following rare liver disease or liver disorders genetically caused or involving altered immunity including  primary sclerosing cholangitis, primary biliary cholangiopathy, cystic fibrosis, progressive familial intrahepatic cholestasis, Wilson's disease, biliary atresia, congenital hepatic fibrosis, Caroli disease, polycystic liver diseases or other congenital/metabolic liver disease including undiagnosed biliary disease.